Danio rerio

24 known processes

atr

ataxia telangiectasia and Rad3 related

(Aliases: si:dkey-231j24.1)

atr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.074
signal transductionGO:00071654550.072
larval developmentGO:000216420.063
aromatic compound biosynthetic processGO:00194382170.047
heterocycle metabolic processGO:00464832900.047
positive regulation of transportGO:005105020.046
immune system processGO:00023762410.045
morphogenesis of an epitheliumGO:00020093330.044
nuclear transportGO:005116940.043
nitrogen compound metabolic processGO:00068073190.042
maintenance of locationGO:005123540.042
cell surface receptor signaling pathwayGO:00071663250.042
central nervous system developmentGO:00074173870.041
organic substance biosynthetic processGO:19015762890.040
neuron differentiationGO:00301823530.040
regulation of metabolic processGO:00192223590.040
cellular macromolecule metabolic processGO:00442603910.039
negative regulation of biological processGO:00485193040.038
response to chemicalGO:00422213200.038
sensory organ developmentGO:00074233930.038
head developmentGO:00603223030.038
negative regulation of cellular processGO:00485232830.038
cellular nitrogen compound metabolic processGO:00346412900.038
regulation of response to stimulusGO:00485832690.037
nucleocytoplasmic transportGO:000691340.037
regulation of intracellular protein transportGO:003315730.037
protein localization to nucleusGO:003450430.037
digestive tract morphogenesisGO:00485462310.036
regulation of establishment of protein localizationGO:007020140.036
establishment of protein localization to organelleGO:007259440.035
multicellular organism growthGO:003526440.035
regulation of cellular metabolic processGO:00313233200.035
heterocycle biosynthetic processGO:00181302150.035
positive regulation of cellular component biogenesisGO:004408930.034
gene expressionGO:00104672520.034
generation of neuronsGO:00486993850.034
organic cyclic compound metabolic processGO:19013603010.034
regulation of signal transductionGO:00099662250.033
regulation of macromolecule metabolic processGO:00602553170.033
nucleic acid metabolic processGO:00903042440.033
regulation of protein transportGO:005122330.033
single organism nuclear importGO:190259330.033
cellular protein catabolic processGO:004425740.033
protein targeting to nucleusGO:004474430.033
nucleobase containing compound metabolic processGO:00061392740.033
tube morphogenesisGO:00352393490.032
cell projection organizationGO:00300302840.032
regulation of synapse assemblyGO:005196330.032
response to drugGO:004249330.031
regulation of synapse organizationGO:005080730.031
protein import into nucleusGO:000660630.031
locomotionGO:00400113130.031
nucleobase containing compound biosynthetic processGO:00346542050.031
digestive system developmentGO:00551232890.031
cell part morphogenesisGO:00329902460.031
positive regulation of cell cycleGO:004578730.031
biosynthetic processGO:00090582940.031
cellular aromatic compound metabolic processGO:00067252950.031
cellular component movementGO:00069283350.030
embryonic organ developmentGO:00485683810.030
organic cyclic compound biosynthetic processGO:19013622230.030
regulation of multicellular organism growthGO:004001440.030
regulation of cellular amine metabolic processGO:003323800.030
negative regulation of protein phosphorylationGO:000193340.030
stem cell maintenanceGO:001982740.030
modification dependent protein catabolic processGO:001994130.030
guanosine containing compound metabolic processGO:190106840.030
cellular component morphogenesisGO:00329893360.030
regulation of cytoplasmic transportGO:190364940.029
regulation of protein targetingGO:190353320.029
phagocytosisGO:000690930.029
cellular nitrogen compound biosynthetic processGO:00442712180.029
brain developmentGO:00074202930.028
regulation of protein localization to nucleusGO:190018020.028
regulation of protein import into nucleusGO:004230620.028
eye developmentGO:00016542770.028
single organism metabolic processGO:00447102170.028
cellular macromolecule biosynthetic processGO:00346452240.028
cell projection morphogenesisGO:00488582440.028
regulation of developmental processGO:00507932470.028
stem cell proliferationGO:007208940.028
macromolecule biosynthetic processGO:00090592270.028
cellular ketone metabolic processGO:0042180110.028
regulation of cytokine productionGO:000181730.028
rna metabolic processGO:00160702190.028
regulation of signalingGO:00230512350.027
amine metabolic processGO:000930820.027
regulation of cellular ketone metabolic processGO:001056570.027
regulation of gene expressionGO:00104682650.027
mononuclear cell proliferationGO:003294310.027
protein importGO:001703830.027
lipid storageGO:001991510.027
regulation of cell communicationGO:00106462320.027
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.026
blood vessel developmentGO:00015682460.026
leukocyte proliferationGO:007066110.026
regulation of epithelial cell proliferationGO:005067830.026
mitochondrion organizationGO:000700540.026
regulation of biological qualityGO:00650082630.026
modification dependent macromolecule catabolic processGO:004363230.026
regulation of cellular amino acid metabolic processGO:000652100.026
regionalizationGO:00030022740.026
transcription dna templatedGO:00063511810.026
regulation of metal ion transportGO:001095940.026
regulation of nitrogen compound metabolic processGO:00511712510.026
regulation of primary metabolic processGO:00800903110.025
response to external stimulusGO:00096052640.025
regulation of nucleocytoplasmic transportGO:004682220.025
proteasomal protein catabolic processGO:001049820.025
regulation of multicellular organismal processGO:00512392770.025
extrinsic apoptotic signaling pathwayGO:009719130.025
cellular amine metabolic processGO:004410620.025
retina development in camera type eyeGO:00600411460.025
positive regulation of cellular amino acid metabolic processGO:004576400.025
proteolysis involved in cellular protein catabolic processGO:005160330.025
guanosine containing compound catabolic processGO:190106920.025
rna biosynthetic processGO:00327741810.024
regulation of protein modification by small protein conjugation or removalGO:190332030.024
ubiquitin dependent protein catabolic processGO:000651130.024
nuclear importGO:005117030.024
cell migrationGO:00164772370.024
gtp metabolic processGO:004603940.024
localization of cellGO:00516742440.024
protein metabolic processGO:00195381830.024
cell morphogenesisGO:00009022890.024
gtp catabolic processGO:000618420.024
regulation of multicellular organismal developmentGO:20000262230.024
embryonic organ morphogenesisGO:00485622740.024
positive regulation of epithelial cell proliferationGO:005067910.024
cell substrate adhesionGO:003158940.023
regulation of protein ubiquitinationGO:003139630.023
regulation of transcription dna templatedGO:00063552130.023
nucleic acid templated transcriptionGO:00976591810.023
cellular biosynthetic processGO:00442492860.023
positive regulation of cellular catabolic processGO:003133130.023
digestive tract developmentGO:00485652650.023
heart developmentGO:00075073130.023
transportGO:00068102200.023
protein acetylationGO:000647320.023
positive regulation of cellular amine metabolic processGO:003324000.023
immune system developmentGO:00025201910.022
gastrulationGO:00073692080.022
positive regulation of cellular processGO:00485222010.022
cell motilityGO:00488702440.022
cell matrix adhesionGO:000716040.022
adherens junction organizationGO:003433240.022
hemopoiesisGO:00300971830.022
cellular component disassemblyGO:002241110.022
regulation of protein catabolic processGO:004217610.022
chordate embryonic developmentGO:00430092710.022
synaptic growth at neuromuscular junctionGO:005112420.022
regulation of bindingGO:005109830.022
neuron developmentGO:00486662620.022
regulation of cell activationGO:005086510.022
regulation of cellular macromolecule biosynthetic processGO:20001122220.022
autophagyGO:000691440.022
determination of left right symmetryGO:00073681790.021
cellular response to lipopolysaccharideGO:007122230.021
regulation of cellular biosynthetic processGO:00313262450.021
hematopoietic or lymphoid organ developmentGO:00485341910.021
sensory organ morphogenesisGO:00905962000.021
vasculature developmentGO:00019442780.021
regulation of stem cell differentiationGO:200073640.021
female gonad developmentGO:000858540.021
cell deathGO:00082191210.021
positive regulation of catabolic processGO:000989640.021
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.021
response to monosaccharideGO:003428430.021
response to carbohydrateGO:000974330.021
positive regulation of jnk cascadeGO:004633030.021
regulation of rna metabolic processGO:00512522240.021
regulation of peptidyl tyrosine phosphorylationGO:005073010.020
positive regulation of biological processGO:00485182530.020
regulation of stem cell proliferationGO:007209120.020
regulation of reproductive processGO:200024140.020
intracellular signal transductionGO:0035556850.020
organelle organizationGO:00069962270.020
regulation of macromolecule biosynthetic processGO:00105562250.020
internal protein amino acid acetylationGO:000647520.020
small molecule metabolic processGO:0044281770.020
lymphocyte proliferationGO:004665110.020
cellular response to nutrient levelsGO:003166920.020
regulation of rna biosynthetic processGO:20011412130.020
peptidyl lysine acetylationGO:001839420.020
regulation of purine nucleotide catabolic processGO:003312120.020
rna localizationGO:000640340.020
peptide transportGO:001583310.020
organonitrogen compound metabolic processGO:1901564740.020
single organism organelle organizationGO:19025891990.020
microtubule organizing center organizationGO:003102310.020
cellular component biogenesisGO:00440851780.019
determination of bilateral symmetryGO:00098552040.019
carboxylic acid metabolic processGO:0019752220.019
establishment of localizationGO:00512342440.019
camera type eye developmentGO:00430102220.019
regulation of biosynthetic processGO:00098892500.019
positive regulation of immune effector processGO:000269930.019
b cell activationGO:004211320.019
neuron projection developmentGO:00311751800.019
meiotic nuclear divisionGO:000712640.019
response to stressGO:00069502630.019
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.019
cellular protein metabolic processGO:00442671290.019
oxoacid metabolic processGO:0043436310.019
regulation of cell shapeGO:000836010.019
deathGO:00162651210.019
negative regulation of protein kinase activityGO:000646940.019
cellular response to starvationGO:000926710.019
adult behaviorGO:003053420.019
single fertilizationGO:000733830.019
protein acylationGO:004354330.019
post embryonic organ developmentGO:004856940.018
cellular response to biotic stimulusGO:007121630.018
positive regulation of cytokine productionGO:000181920.018
regulation of nucleotide catabolic processGO:003081120.018
regulation of cell deathGO:00109411030.018
negative regulation of cytoplasmic transportGO:190365020.018
regulation of protein complex assemblyGO:004325430.018
organic acid metabolic processGO:0006082310.018
cellular response to external stimulusGO:007149620.018
positive regulation of stress activated mapk cascadeGO:003287430.018
cellular amino acid metabolic processGO:000652070.018
response to organic substanceGO:00100331530.018
negative regulation of protein transportGO:005122430.018
internal peptidyl lysine acetylationGO:001839320.018
negative regulation of catabolic processGO:000989530.018
response to glucoseGO:000974930.018
regulation of neural precursor cell proliferationGO:200017730.018
regulation of synaptic growth at neuromuscular junctionGO:000858210.018
convergent extensionGO:00600261180.018
cellular response to extracellular stimulusGO:003166820.018
response to uvGO:000941130.018
somatic muscle developmentGO:000752540.018
female sex differentiationGO:004666040.018
single organism membrane fusionGO:004480120.018
single organism localizationGO:19025782250.018
regulation of extrinsic apoptotic signaling pathwayGO:200123630.018
cellular response to molecule of bacterial originGO:007121930.017
neuron projection morphogenesisGO:00488121610.017
monocyte differentiationGO:003022420.017
single organism transportGO:00447652060.017
negative regulation of nucleocytoplasmic transportGO:004682320.017
regulation of i kappab kinase nf kappab signalingGO:004312240.017
embryo development ending in birth or egg hatchingGO:00097922710.017
specification of symmetryGO:00097992040.017
eye morphogenesisGO:00485921440.017
blood vessel morphogenesisGO:00485142160.017
angiogenesisGO:00015251580.017
regulation of cell differentiationGO:00455951420.017
dorsal ventral pattern formationGO:00099531250.017
somitogenesisGO:0001756870.017
negative regulation of cellular catabolic processGO:003133030.017
i kappab kinase nf kappab signalingGO:000724940.017
muscle structure developmentGO:00610611960.017
negative regulation of intracellular transportGO:003238730.017
germ line stem cell maintenanceGO:003071820.017
regulation of nucleobase containing compound metabolic processGO:00192192500.017
regulation of endothelial cell proliferationGO:000193610.017
positive regulation of secretionGO:005104710.016
exocytosisGO:000688710.016
response to hexoseGO:000974630.016
transcription from rna polymerase ii promoterGO:0006366800.016
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.016
ribonucleoside monophosphate catabolic processGO:000915840.016
cellular response to chemical stimulusGO:00708871570.016
anterior posterior pattern specificationGO:00099521520.016
regulation of autophagyGO:001050630.016
positive regulation of translationGO:004572710.016
negative regulation of kinase activityGO:003367340.016
b cell differentiationGO:003018310.016
tissue remodelingGO:004877140.016
negative regulation of cytokine productionGO:000181810.016
macromolecule modificationGO:00434121110.016
developmental growthGO:00485891660.016
membrane fusionGO:006102520.016
positive regulation of cytoskeleton organizationGO:005149530.016
regulation of dendrite developmentGO:005077330.016
positive regulation of protein complex assemblyGO:003133420.016
wnt signaling pathwayGO:0016055800.016
actin polymerization or depolymerizationGO:000815420.016
endosomal transportGO:001619720.016
peptidyl serine phosphorylationGO:001810510.016
production of molecular mediator of immune responseGO:000244020.016
regulation of protein bindingGO:004339330.015
cytokinesisGO:000091030.015
organelle fusionGO:004828430.015
atp catabolic processGO:000620040.015
regulation of mrna processingGO:005068430.015
response to nutrientGO:000758430.015
protein modification processGO:00362111000.015
axon developmentGO:00615641660.015
cellular response to radiationGO:007147840.015
regulation of cell matrix adhesionGO:000195210.015
protein localization to plasma membraneGO:007265910.015
regulation of apoptotic processGO:0042981980.015
regulation of gtp catabolic processGO:003312420.015
membrane invaginationGO:001032410.015
regulation of nucleic acid templated transcriptionGO:19035062130.015
phagocytosis engulfmentGO:000691110.015
interspecies interaction between organismsGO:004441940.015
regulation of nucleoside metabolic processGO:000911820.015
lateral inhibitionGO:004633110.015
positive regulation of nucleoside metabolic processGO:004597910.015
system processGO:00030081850.015
regulation of blood pressureGO:000821710.015
positive regulation of secretion by cellGO:190353210.015
regulation of cell substrate adhesionGO:001081010.015
protein homooligomerizationGO:005126030.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
secondary metabolic processGO:001974830.015
negative regulation of metabolic processGO:0009892860.015
cell morphogenesis involved in differentiationGO:00009041950.015
negative regulation of epithelial cell proliferationGO:005068010.015
regulation of programmed cell deathGO:00430671010.015
development of primary female sexual characteristicsGO:004654540.015
peptidyl serine modificationGO:001820920.015
somatic stem cell maintenanceGO:003501910.015
negative regulation of protein localization to nucleusGO:190018120.015
cellular component assemblyGO:00226071700.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
meiotic cell cycle processGO:190304630.014
nucleoside monophosphate catabolic processGO:000912540.014
compound eye developmentGO:004874920.014
regulation of reactive oxygen species metabolic processGO:200037720.014
sensory perception of chemical stimulusGO:000760630.014
programmed cell deathGO:00125011190.014
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018440.014
apoptotic processGO:00069151160.014
regulation of production of molecular mediator of immune responseGO:000270010.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
regulation of dna replicationGO:000627530.014
axonogenesisGO:00074091520.014
fertilizationGO:000956630.014
heart morphogenesisGO:00030071560.014
hormone transportGO:000991420.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
tube closureGO:006060610.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.014
regulation of erk1 and erk2 cascadeGO:007037240.014
locomotor rhythmGO:004547530.014
ear developmentGO:00435831270.014
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.014
negative regulation of protein import into nucleusGO:004230820.014
cellular response to oxygen levelsGO:007145310.014
pancreas developmentGO:0031016840.014
erk1 and erk2 cascadeGO:007037140.014
hormone secretionGO:004687920.014
protein dephosphorylationGO:000647030.014
negative regulation of dna metabolic processGO:005105340.014
response to alkaloidGO:004327920.014
macroautophagyGO:001623610.014
positive regulation of nucleotide catabolic processGO:003081310.014
response to corticosteroidGO:003196010.014
stem cell differentiationGO:00488631170.014
regulation of hormone secretionGO:004688320.013
negative regulation of chromosome organizationGO:200125110.013
gland developmentGO:00487321430.013
cilium morphogenesisGO:0060271850.013
cellular protein modification processGO:00064641000.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
positive regulation of cell adhesionGO:004578510.013
liver developmentGO:0001889960.013
homeostatic processGO:00425921420.013
cell morphogenesis involved in neuron differentiationGO:00486671630.013
positive regulation of epithelial cell differentiationGO:003085820.013
protein complex disassemblyGO:004324110.013
positive regulation of map kinase activityGO:004340630.013
primary neural tube formationGO:001402010.013
enzyme linked receptor protein signaling pathwayGO:00071671060.013
embryonic heart tube developmentGO:00350501330.013
regulation of meiotic cell cycleGO:005144510.013
negative regulation of cell communicationGO:0010648960.013
regulation of gtpase activityGO:004308720.013
cellular response to organic substanceGO:00713101050.013
immunoglobulin mediated immune responseGO:001606430.013
glucose homeostasisGO:004259310.013
nuclear exportGO:005116810.013
ovulation cycle processGO:002260220.013
protein stabilizationGO:005082120.013
protein secretionGO:000930610.013
skeletal system developmentGO:00015011810.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
growthGO:00400071740.013
positive regulation of nitrogen compound metabolic processGO:0051173690.013
determination of heart left right asymmetryGO:00613711170.013
positive regulation of cell divisionGO:005178120.013
camera type eye morphogenesisGO:00485931080.013
cellular response to stressGO:0033554620.013
connective tissue developmentGO:0061448990.013
macromolecular complex disassemblyGO:003298410.013
positive regulation of dna metabolic processGO:005105410.013
regulation of response to extracellular stimulusGO:003210410.013
regulation of inflammatory responseGO:005072720.013
regulation of mesenchymal cell proliferationGO:001046410.013
negative regulation of signal transductionGO:0009968940.013
carbohydrate homeostasisGO:003350010.013
regulation of dendrite morphogenesisGO:004881430.012
regulation of cellular protein catabolic processGO:190336210.012
somite developmentGO:0061053960.012
positive regulation of gtpase activityGO:004354710.012
negative regulation of mapk cascadeGO:004340940.012
retina morphogenesis in camera type eyeGO:0060042790.012
phosphate containing compound metabolic processGO:00067961080.012
negative regulation of ras protein signal transductionGO:004658010.012
phosphorus metabolic processGO:00067931090.012
positive regulation of muscle cell differentiationGO:005114910.012
antimicrobial humoral responseGO:001973020.012
cilium organizationGO:0044782710.012
positive regulation of neuron apoptotic processGO:004352510.012
negative regulation of intracellular protein transportGO:009031730.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
chemotaxisGO:00069351040.012
purine nucleoside monophosphate catabolic processGO:000912840.012
hepaticobiliary system developmentGO:0061008980.012
regulation of organelle assemblyGO:190211540.012
positive regulation of cell activationGO:005086710.012
ameboidal type cell migrationGO:00016671430.012
regulation of nervous system developmentGO:0051960900.012
negative regulation of gene expressionGO:0010629650.012
lipid catabolic processGO:001604240.012
cognitionGO:005089010.012
peptidyl threonine phosphorylationGO:001810710.012
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
stem cell divisionGO:001714510.012
neuroblast proliferationGO:000740520.012
muscle cell differentiationGO:00426921390.012
protein polymerizationGO:005125840.012
regulation of jak stat cascadeGO:004642530.012
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.012
regulation of response to biotic stimulusGO:000283120.012
mesenchyme developmentGO:00604851270.012
taxisGO:00423301090.012
cell substrate junction assemblyGO:000704420.012
positive regulation of epithelial cell migrationGO:001063420.012
zymogen activationGO:003163830.012
pigmentationGO:0043473850.012
cellular carbohydrate metabolic processGO:004426240.012
negative regulation of response to stimulusGO:00485851040.012
regulation of calcium ion transportGO:005192420.011
phosphatidylinositol mediated signalingGO:004801520.011
negative regulation of macromolecule metabolic processGO:0010605760.011
epithelial tube morphogenesisGO:00605621480.011
negative regulation of synapse assemblyGO:005196420.011
cell proliferationGO:0008283800.011
positive regulation of chromosome organizationGO:200125210.011
lateral line system developmentGO:0048925760.011
g1 s transition of mitotic cell cycleGO:000008210.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
negative regulation of signalingGO:0023057960.011
regulation of anatomical structure morphogenesisGO:00226031300.011
regenerationGO:0031099910.011
positive regulation of gtp catabolic processGO:003312610.011
positive regulation of erk1 and erk2 cascadeGO:007037420.011
negative regulation of biosynthetic processGO:0009890550.011
urogenital system developmentGO:0001655970.011
negative regulation of apoptotic processGO:0043066550.011
regulation of cell developmentGO:00602841000.011
response to woundingGO:00096111160.011
negative regulation of cellular metabolic processGO:0031324770.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
recombinational repairGO:000072510.011
regulation of cellular component organizationGO:0051128860.011
inositol lipid mediated signalingGO:004801720.011
b cell mediated immunityGO:001972430.011
cellular response to hypoxiaGO:007145610.011
cellular amide metabolic processGO:004360340.011
negative regulation of defense responseGO:003134820.011
embryonic skeletal system developmentGO:0048706970.011
signal transduction in absence of ligandGO:003803410.011
regulation of blood vessel sizeGO:005088020.011
cytosolic calcium ion transportGO:006040130.011
regulation of carbohydrate metabolic processGO:000610940.011
positive regulation of ras protein signal transductionGO:004657910.011
regulation of tube sizeGO:003515020.011
positive regulation of neuron deathGO:190121610.011
sequestering of calcium ionGO:005120830.011
renal system developmentGO:0072001940.011
toll like receptor signaling pathwayGO:000222440.011
cellular localizationGO:0051641970.011
inner ear developmentGO:00488391260.011

atr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
disease of metabolismDOID:001466700.021
musculoskeletal system diseaseDOID:1700.020
immune system diseaseDOID:291400.019
nervous system diseaseDOID:86300.018
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
organ system cancerDOID:005068600.016
muscle tissue diseaseDOID:6600.013
myopathyDOID:42300.013
muscular diseaseDOID:008000000.013
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.012
eye diseaseDOID:561400.012
inherited metabolic disorderDOID:65500.012