Danio rerio

0 known processes

unc50

unc-50 homolog (C. elegans)

(Aliases: MGC56114,zgc:56114)

unc50 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
golgi vesicle transportGO:004819330.128
larval developmentGO:000216420.061
ubiquitin dependent protein catabolic processGO:000651130.061
agingGO:000756820.053
homeostatic processGO:00425921420.051
organelle fusionGO:004828430.048
cellular macromolecule metabolic processGO:00442603910.043
modification dependent protein catabolic processGO:001994130.042
proteolysis involved in cellular protein catabolic processGO:005160330.042
cellular response to starvationGO:000926710.040
regulation of biological qualityGO:00650082630.040
membrane fusionGO:006102520.039
cellular response to external stimulusGO:007149620.037
modification dependent macromolecule catabolic processGO:004363230.034
response to stressGO:00069502630.034
cellular protein catabolic processGO:004425740.033
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.032
cellular response to nutrient levelsGO:003166920.032
er nucleus signaling pathwayGO:000698420.032
single organism transportGO:00447652060.031
negative regulation of biological processGO:00485193040.031
proteasomal protein catabolic processGO:001049820.029
single organism localizationGO:19025782250.028
positive regulation of apoptotic signaling pathwayGO:200123510.027
positive regulation of catabolic processGO:000989640.026
transportGO:00068102200.026
positive regulation of protein complex assemblyGO:003133420.025
cellular response to extracellular stimulusGO:003166820.025
multicellular organism growthGO:003526440.025
protein localization to plasma membraneGO:007265910.025
regulation of i kappab kinase nf kappab signalingGO:004312240.025
regulation of protein catabolic processGO:004217610.025
synaptic vesicle recyclingGO:003646510.025
maintenance of locationGO:005123540.025
cellular biosynthetic processGO:00442492860.024
negative regulation of cellular catabolic processGO:003133030.024
endosomal transportGO:001619720.024
response to unfolded proteinGO:000698620.023
chemical homeostasisGO:0048878490.023
synaptic vesicle localizationGO:009747910.023
regulation of cytokine productionGO:000181730.023
cytoskeleton dependent cytokinesisGO:006164030.023
deathGO:00162651210.023
meiotic nuclear divisionGO:000712640.022
regulation of protein complex assemblyGO:004325430.022
phagocytosisGO:000690930.022
autophagyGO:000691440.022
macromolecule modificationGO:00434121110.022
synaptic vesicle transportGO:004848910.021
establishment of localizationGO:00512342440.021
establishment of protein localization to organelleGO:007259440.021
lipid storageGO:001991510.021
regulation of intracellular phGO:005145310.021
response to topologically incorrect proteinGO:003596620.021
cellular monovalent inorganic cation homeostasisGO:003000420.020
meiotic cell cycle processGO:190304630.020
cell deathGO:00082191210.020
negative regulation of catabolic processGO:000989530.020
macroautophagyGO:001623610.020
organonitrogen compound metabolic processGO:1901564740.019
single organism metabolic processGO:00447102170.019
protein importGO:001703830.019
regulation of cytoplasmic transportGO:190364940.019
programmed cell deathGO:00125011190.019
response to chemicalGO:00422213200.019
protein polyubiquitinationGO:000020940.018
heterocycle metabolic processGO:00464832900.018
regulation of multicellular organism growthGO:004001440.018
regulation of nucleocytoplasmic transportGO:004682220.018
locomotionGO:00400113130.018
regulation of cellular ketone metabolic processGO:001056570.018
stem cell divisionGO:001714510.018
negative regulation of cell deathGO:0060548600.018
positive regulation of cytosolic calcium ion concentrationGO:000720440.018
guanosine containing compound metabolic processGO:190106840.018
er to golgi vesicle mediated transportGO:000688810.018
cellular response to unfolded proteinGO:003462020.017
synaptic vesicle endocytosisGO:004848810.017
establishment of synaptic vesicle localizationGO:009748010.017
regulation of cellular amino acid metabolic processGO:000652100.017
cellular transition metal ion homeostasisGO:004691630.017
tube morphogenesisGO:00352393490.017
extrinsic apoptotic signaling pathwayGO:009719130.017
gland developmentGO:00487321430.017
cell surface receptor signaling pathwayGO:00071663250.017
protein metabolic processGO:00195381830.017
regulation of carbohydrate metabolic processGO:000610940.017
regulation of hormone secretionGO:004688320.017
i kappab kinase nf kappab signalingGO:000724940.017
compound eye developmentGO:004874920.016
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.016
lipid catabolic processGO:001604240.016
regulation of bindingGO:005109830.016
organelle organizationGO:00069962270.016
regulation of phGO:000688530.016
biosynthetic processGO:00090582940.016
protein n linked glycosylationGO:000648710.016
establishment of protein localization to plasma membraneGO:009000210.016
negative regulation of cellular processGO:00485232830.016
regulation of apoptotic processGO:0042981980.016
xenobiotic metabolic processGO:000680540.016
regulation of nucleotide catabolic processGO:003081120.016
apoptotic processGO:00069151160.016
cellular protein modification processGO:00064641000.016
embryo development ending in birth or egg hatchingGO:00097922710.016
protein secretionGO:000930610.015
regulation of extrinsic apoptotic signaling pathwayGO:200123630.015
golgi organizationGO:000703010.015
morphogenesis of an epitheliumGO:00020093330.015
regulation of macromolecule metabolic processGO:00602553170.015
cell motilityGO:00488702440.015
nucleocytoplasmic transportGO:000691340.015
cation homeostasisGO:0055080330.015
regulation of programmed cell deathGO:00430671010.015
positive regulation of cellular catabolic processGO:003133130.015
endoplasmic reticulum unfolded protein responseGO:003096820.015
regulation of cellular carbohydrate metabolic processGO:001067540.015
positive regulation of transportGO:005105020.015
organic cyclic compound metabolic processGO:19013603010.014
amine metabolic processGO:000930820.014
specification of symmetryGO:00097992040.014
hemopoiesisGO:00300971830.014
organic substance biosynthetic processGO:19015762890.014
regulation of cellular amine metabolic processGO:003323800.014
cellular carbohydrate metabolic processGO:004426240.014
regulation of protein transportGO:005122330.014
erythrocyte homeostasisGO:0034101550.014
interspecies interaction between organismsGO:004441940.014
cellular ketone metabolic processGO:0042180110.014
ion homeostasisGO:0050801410.014
oxoacid metabolic processGO:0043436310.013
regulation of intracellular protein transportGO:003315730.013
notch signaling pathwayGO:0007219350.013
embryonic organ developmentGO:00485683810.013
cellular amine metabolic processGO:004410620.013
regulation of cellular metabolic processGO:00313233200.013
determination of left right symmetryGO:00073681790.013
nuclear importGO:005117030.013
cellular modified amino acid metabolic processGO:000657530.013
single organism nuclear importGO:190259330.013
ion transmembrane transportGO:0034220910.012
cellular amino acid metabolic processGO:000652070.012
lipoprotein metabolic processGO:004215740.012
pole plasm assemblyGO:000731540.012
positive regulation of map kinase activityGO:004340630.012
regulation of cellular protein catabolic processGO:190336210.012
cell cycle g2 m phase transitionGO:004483940.012
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.012
guanosine containing compound catabolic processGO:190106920.012
secondary metabolic processGO:001974830.012
negative regulation of protein complex assemblyGO:003133310.012
cell death in response to oxidative stressGO:003647320.012
organic acid metabolic processGO:0006082310.012
response to drugGO:004249330.012
regulation of cell deathGO:00109411030.012
nephron epithelium morphogenesisGO:007208810.012
spindle assembly involved in mitosisGO:009030710.012
nucleobase containing compound metabolic processGO:00061392740.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
cell part morphogenesisGO:00329902460.012
negative regulation of programmed cell deathGO:0043069580.012
nucleic acid transportGO:005065720.012
regulation of protein modification by small protein conjugation or removalGO:190332030.012
positive regulation of cell cycleGO:004578730.012
regulation of protein ubiquitinationGO:003139630.012
growthGO:00400071740.012
cellular response to topologically incorrect proteinGO:003596720.012
cellular respirationGO:004533330.012
heart morphogenesisGO:00030071560.012
primary neural tube formationGO:001402010.012
single organism membrane fusionGO:004480120.012
regulation of reproductive processGO:200024140.012
cellular component morphogenesisGO:00329893360.012
hormone transportGO:000991420.011
regulation of nucleoside metabolic processGO:000911820.011
regulation of synaptic plasticityGO:004816710.011
determination of bilateral symmetryGO:00098552040.011
sensory organ developmentGO:00074233930.011
nitrogen compound metabolic processGO:00068073190.011
negative regulation of nuclear divisionGO:005178430.011
regulation of metal ion transportGO:001095940.011
aromatic compound biosynthetic processGO:00194382170.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
cellular component movementGO:00069283350.011
regulation of response to oxidative stressGO:190288220.011
meiotic chromosome segregationGO:004513230.011
small molecule metabolic processGO:0044281770.011
head developmentGO:00603223030.011
mitochondrion organizationGO:000700540.011
lytic vacuole organizationGO:008017110.011
rna biosynthetic processGO:00327741810.011
spermatid differentiationGO:004851520.011
protein polymerizationGO:005125840.011
heart developmentGO:00075073130.011
multi organism processGO:00517041340.011
positive regulation of cytokine productionGO:000181920.011
regulation of metabolic processGO:00192223590.011
regulation of jun kinase activityGO:004350630.011
regulation of protein import into nucleusGO:004230620.011
atp catabolic processGO:000620040.011
cell projection organizationGO:00300302840.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
ion transportGO:00068111140.011
hepaticobiliary system developmentGO:0061008980.011
antimicrobial humoral responseGO:001973020.011
glial cell migrationGO:000834730.011
rna localizationGO:000640340.011
activation of mapk activityGO:000018730.011
olfactory lobe developmentGO:002198840.010
somatic stem cell maintenanceGO:003501910.010
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.010
cell migrationGO:00164772370.010
type b pancreatic cell developmentGO:000332340.010
regulation of protein targetingGO:190353320.010
symbiosis encompassing mutualism through parasitismGO:004440340.010
blood vessel developmentGO:00015682460.010
single organism organelle organizationGO:19025891990.010
gtp catabolic processGO:000618420.010
regulation of epithelial cell proliferationGO:005067830.010
mitotic cytokinesisGO:000028130.010
regulation of meiotic cell cycleGO:005144510.010
cellular cation homeostasisGO:0030003170.010
brain developmentGO:00074202930.010
exocytosisGO:000688710.010
response to alkaloidGO:004327920.010
regulation of primary metabolic processGO:00800903110.010
cellular response to molecule of bacterial originGO:007121930.010
cellular protein metabolic processGO:00442671290.010
adult behaviorGO:003053420.010
negative regulation of apoptotic processGO:0043066550.010
ribonucleoside monophosphate catabolic processGO:000915840.010
regulation of purine nucleotide catabolic processGO:003312120.010
negative regulation of multi organism processGO:004390130.010
protein k48 linked ubiquitinationGO:007093610.010

unc50 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.028
disease of anatomical entityDOID:700.028
disease of cellular proliferationDOID:1456600.023
disease of metabolismDOID:001466700.020
inherited metabolic disorderDOID:65500.018
lysosomal storage diseaseDOID:321100.016
cancerDOID:16200.014
organ system cancerDOID:005068600.013
musculoskeletal system diseaseDOID:1700.011