Danio rerio

14 known processes

npm4

nucleophosmin/nucleoplasmin, 4

(Aliases: npm1b)

npm4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immune system processGO:00023762410.351
hemopoiesisGO:00300971830.214
response to transition metal nanoparticleGO:1990267280.148
ameboidal type cell migrationGO:00016671430.147
response to nutrientGO:000758430.130
t cell differentiationGO:003021760.122
digestive tract morphogenesisGO:00485462310.112
transmembrane transportGO:00550851200.104
response to chemicalGO:00422213200.102
Human
single organism transportGO:00447652060.097
Mouse
locomotionGO:00400113130.087
negative regulation of protein kinase activityGO:000646940.085
Human
maintenance of locationGO:005123540.084
hematopoietic or lymphoid organ developmentGO:00485341910.080
tube morphogenesisGO:00352393490.076
cellular response to chemical stimulusGO:00708871570.076
Human
negative regulation of cellular processGO:00485232830.072
Human Mouse
cellular component movementGO:00069283350.071
agingGO:000756820.069
Human
translational initiationGO:000641330.069
gastrulationGO:00073692080.067
ion transportGO:00068111140.066
immune system developmentGO:00025201910.064
positive regulation of transportGO:005105020.063
female sex differentiationGO:004666040.063
establishment of localizationGO:00512342440.058
Human Mouse
transportGO:00068102200.057
Human Mouse
positive regulation of map kinase activityGO:004340630.055
generation of neuronsGO:00486993850.055
sensory system developmentGO:0048880760.053
negative regulation of kinase activityGO:003367340.052
Human
response to corticosteroidGO:003196010.051
sensory organ developmentGO:00074233930.050
regulation of translational initiationGO:000644610.050
Human
neuromast developmentGO:0048884460.049
response to organic substanceGO:00100331530.049
Human
central nervous system developmentGO:00074173870.049
cell projection organizationGO:00300302840.048
nucleic acid transportGO:005065720.047
Mouse
protein complex localizationGO:003150310.046
digestive system developmentGO:00551232890.046
sprouting angiogenesisGO:0002040530.046
rna export from nucleusGO:000640510.046
Mouse
response to ketoneGO:190165410.046
cellular protein modification processGO:00064641000.044
Human Mouse
regulation of extrinsic apoptotic signaling pathwayGO:200123630.044
cell part morphogenesisGO:00329902460.044
muscle cell developmentGO:00550011150.043
stem cell maintenanceGO:001982740.041
Mouse
regulation of protein bindingGO:004339330.041
response to external biotic stimulusGO:0043207970.040
skeletal muscle tissue developmentGO:0007519670.040
angiogenesisGO:00015251580.040
actin cytoskeleton organizationGO:0030036630.039
retina layer formationGO:0010842240.039
intracellular signal transductionGO:0035556850.039
Mouse
protein dephosphorylationGO:000647030.038
cell agingGO:000756920.037
Human
centrosome duplicationGO:005129810.037
Human Mouse
regulation of wound healingGO:006104120.037
cognitionGO:005089010.036
mesoderm developmentGO:0007498880.036
Mouse
cell motilityGO:00488702440.036
cell migration involved in gastrulationGO:0042074790.036
regulation of protein transportGO:005122330.035
positive regulation of cell cycleGO:004578730.035
Mouse
small molecule metabolic processGO:0044281770.035
single organism localizationGO:19025782250.035
Mouse
regulation of multicellular organismal processGO:00512392770.035
organelle organizationGO:00069962270.034
Human Mouse
organic acid metabolic processGO:0006082310.034
regulation of cellular ketone metabolic processGO:001056570.034
metal ion transportGO:0030001580.034
regulation of bindingGO:005109830.033
stem cell differentiationGO:00488631170.033
Mouse
regulation of biological qualityGO:00650082630.033
Mouse
neuron projection morphogenesisGO:00488121610.033
cellular response to dsrnaGO:007135910.033
Human
cation transportGO:0006812810.033
multicellular organism growthGO:003526440.033
striated muscle cell developmentGO:00550021080.032
positive regulation of myeloid cell differentiationGO:004563920.032
regulation of localizationGO:00328791040.032
localization of cellGO:00516742440.032
nucleocytoplasmic transportGO:000691340.032
Human Mouse
cell morphogenesisGO:00009022890.032
signal transductionGO:00071654550.031
Mouse
positive regulation of translationGO:004572710.031
Human
amine metabolic processGO:000930820.031
nitrogen compound metabolic processGO:00068073190.031
Human Mouse
negative regulation of protein phosphorylationGO:000193340.031
Human
cell migrationGO:00164772370.031
response to amino acidGO:004320020.030
regulation of cellular amino acid metabolic processGO:000652100.030
lipid storageGO:001991510.030
b cell differentiationGO:003018310.030
regulation of dna catabolic processGO:190362410.030
Human
regulation of metal ion transportGO:001095940.029
cellular response to organic substanceGO:00713101050.029
Human
heart contractionGO:0060047710.029
morphogenesis of an epitheliumGO:00020093330.029
regulation of establishment of protein localizationGO:007020140.029
protein modification processGO:00362111000.028
Human Mouse
lateral line developmentGO:0048882660.028
rna transportGO:005065820.028
Mouse
protein localization to nucleusGO:003450430.028
extrinsic apoptotic signaling pathwayGO:009719130.028
head developmentGO:00603223030.028
positive regulation of dna metabolic processGO:005105410.028
t cell differentiation in thymusGO:003307760.028
exocrine pancreas developmentGO:0031017280.028
ribosomal small subunit biogenesisGO:004227420.028
Mouse
leukocyte proliferationGO:007066110.027
convergent extension involved in gastrulationGO:0060027710.027
regulation of protein modification by small protein conjugation or removalGO:190332030.027
regulation of synapse assemblyGO:005196330.027
cell morphogenesis involved in neuron differentiationGO:00486671630.027
homeostatic processGO:00425921420.027
Mouse
protein metabolic processGO:00195381830.026
Human Mouse
digestive tract developmentGO:00485652650.026
vasculature developmentGO:00019442780.026
cellular response to stressGO:0033554620.026
Human Mouse
lateral inhibitionGO:004633110.026
cellular component assembly involved in morphogenesisGO:00109271070.026
muscle structure developmentGO:00610611960.026
cellular transition metal ion homeostasisGO:004691630.025
chemical homeostasisGO:0048878490.025
regulation of organelle assemblyGO:190211540.025
Human
sequestering of metal ionGO:005123830.025
rna localizationGO:000640340.025
Mouse
retina morphogenesis in camera type eyeGO:0060042790.025
response to glucocorticoidGO:005138410.025
cellular ketone metabolic processGO:0042180110.025
regulation of cellular component movementGO:0051270550.025
cellular amine metabolic processGO:004410620.024
macromolecule modificationGO:00434121110.024
Human Mouse
programmed cell deathGO:00125011190.024
Human
regulation of cytoplasmic transportGO:190364940.024
peptidyl lysine acetylationGO:001839420.024
somitogenesisGO:0001756870.024
negative regulation of biological processGO:00485193040.024
Human Mouse
regulation of epithelial cell proliferationGO:005067830.024
regulation of signalingGO:00230512350.024
Mouse
negative regulation of mrna metabolic processGO:190331230.024
Mouse
brain developmentGO:00074202930.024
regulation of cellular amine metabolic processGO:003323800.024
inorganic ion transmembrane transportGO:0098660570.024
stem cell proliferationGO:007208940.023
neuromast depositionGO:004888590.023
eye developmentGO:00016542770.023
neuron projection developmentGO:00311751800.023
centrosome organizationGO:005129710.023
Human Mouse
cellular carbohydrate metabolic processGO:004426240.023
somite developmentGO:0061053960.023
lateral line system developmentGO:0048925760.023
retina development in camera type eyeGO:00600411460.023
regulation of response to cytokine stimulusGO:006075930.023
dna catabolic processGO:000630810.023
Human
regulation of calcium ion transportGO:005192420.023
single organism metabolic processGO:00447102170.023
Human
regulation of macromolecule biosynthetic processGO:00105562250.022
Human
cortical cytoskeleton organizationGO:003086510.022
regulation of endothelial cell proliferationGO:000193610.022
negative regulation of cytokine productionGO:000181810.022
oxoacid metabolic processGO:0043436310.022
mitochondrion organizationGO:000700540.022
positive regulation of cytoskeleton organizationGO:005149530.022
Mouse
positive regulation of cell activationGO:005086710.022
protein acetylationGO:000647320.022
transcription dna templatedGO:00063511810.022
Human
chemosensory behaviorGO:000763510.022
autophagyGO:000691440.022
positive regulation of response to stimulusGO:0048584800.021
embryo development ending in birth or egg hatchingGO:00097922710.021
negative regulation of protein transportGO:005122430.021
regulation of mrna splicing via spliceosomeGO:004802430.021
Mouse
cellular protein metabolic processGO:00442671290.021
Human Mouse
regulation of dna damage response signal transduction by p53 class mediatorGO:004351640.021
Mouse
regulation of multicellular organism growthGO:004001440.021
antimicrobial humoral responseGO:001973020.021
regulation of peptidyl tyrosine phosphorylationGO:005073010.021
axon developmentGO:00615641660.021
regulation of intracellular protein transportGO:003315730.021
regulation of molecular functionGO:0065009700.021
Human Mouse
development of primary female sexual characteristicsGO:004654540.021
regulation of protein complex assemblyGO:004325430.020
regulation of cellular metabolic processGO:00313233200.020
Human Mouse
regulation of protein metabolic processGO:0051246560.020
Human Mouse
protein targeting to nucleusGO:004474430.020
response to external stimulusGO:00096052640.020
growthGO:00400071740.020
Mouse
camera type eye developmentGO:00430102220.020
nuclear transportGO:005116940.020
Human Mouse
protein importGO:001703830.020
blood vessel developmentGO:00015682460.020
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.020
regulation of cellular carbohydrate metabolic processGO:001067540.020
regulation of protein ubiquitinationGO:003139630.020
nuclear exportGO:005116810.020
Mouse
phagocytosisGO:000690930.019
regulation of autophagyGO:001050630.019
positive regulation of secretion by cellGO:190353210.019
organic cyclic compound metabolic processGO:19013603010.019
Human Mouse
negative regulation of mrna splicing via spliceosomeGO:004802510.019
Mouse
secondary metabolic processGO:001974830.019
glucose homeostasisGO:004259310.019
lymphocyte proliferationGO:004665110.019
i kappab kinase nf kappab signalingGO:000724940.019
cell volume homeostasisGO:000688410.019
Mouse
actomyosin structure organizationGO:0031032530.019
myeloid cell differentiationGO:0030099860.019
response to biotic stimulusGO:0009607970.019
establishment of protein localization to organelleGO:007259440.019
cell morphogenesis involved in differentiationGO:00009041950.019
protein polymerizationGO:005125840.019
b cell activationGO:004211320.018
neuron projection guidanceGO:0097485860.018
cellular component morphogenesisGO:00329893360.018
regulation of nuclease activityGO:003206910.018
Human
neuron developmentGO:00486662620.018
mononuclear cell proliferationGO:003294310.018
melanocyte migrationGO:009732440.018
heart morphogenesisGO:00030071560.018
regulation of nitrogen compound metabolic processGO:00511712510.018
Human Mouse
positive regulation of molecular functionGO:0044093330.018
Human Mouse
cellular amino acid metabolic processGO:000652070.018
activation of mapk activityGO:000018730.018
response to metal ionGO:0010038340.018
meiotic cell cycle processGO:190304630.018
striated muscle tissue developmentGO:00147061100.018
regulation of reproductive processGO:200024140.018
response to other organismGO:0051707970.018
microtubule organizing center organizationGO:003102310.018
Human Mouse
regulation of cell activationGO:005086510.017
regulation of cell migrationGO:0030334400.017
positive regulation of wound healingGO:009030310.017
heterocycle metabolic processGO:00464832900.017
Human Mouse
single organism nuclear importGO:190259330.017
guanosine containing compound metabolic processGO:190106840.017
eye morphogenesisGO:00485921440.017
cellular response to endogenous stimulusGO:0071495680.017
blood vessel morphogenesisGO:00485142160.017
regulation of primary metabolic processGO:00800903110.017
Human Mouse
regulation of cytokine productionGO:000181730.017
positive regulation of epithelial cell proliferationGO:005067910.017
positive regulation of leukocyte differentiationGO:190210710.017
positive regulation of apoptotic signaling pathwayGO:200123510.017
gtp metabolic processGO:004603940.017
regulation of intracellular signal transductionGO:1902531570.017
Mouse
positive regulation of endothelial cell proliferationGO:000193810.016
regulation of metabolic processGO:00192223590.016
Human Mouse
pancreas developmentGO:0031016840.016
regulation of signal transductionGO:00099662250.016
Mouse
regulation of histone methylationGO:003106030.016
negative regulation of mrna processingGO:005068610.016
Mouse
regulation of immune system processGO:0002682340.016
internal peptidyl lysine acetylationGO:001839320.016
positive regulation of cellular catabolic processGO:003133130.016
regulation of i kappab kinase nf kappab signalingGO:004312240.016
mesenchyme developmentGO:00604851270.016
regulation of programmed cell deathGO:00430671010.016
Human
positive regulation of stem cell proliferationGO:200064810.016
convergent extensionGO:00600261180.016
multi organism processGO:00517041340.016
regulation of cellular protein metabolic processGO:0032268520.015
Human Mouse
organelle assemblyGO:00709251100.015
Human
regulation of developmental processGO:00507932470.015
Mouse
phosphorus metabolic processGO:00067931090.015
Human Mouse
negative regulation of chromosome organizationGO:200125110.015
negative regulation of protein complex assemblyGO:003133310.015
stem cell developmentGO:0048864820.015
Mouse
behaviorGO:0007610740.015
neural retina developmentGO:0003407490.015
cortical actin cytoskeleton organizationGO:003086610.015
positive regulation of catabolic processGO:000989640.015
tissue remodelingGO:004877140.015
system processGO:00030081850.015
response to drugGO:004249330.015
carboxylic acid metabolic processGO:0019752220.015
actin polymerization or depolymerizationGO:000815420.015
regulation of erythrocyte differentiationGO:004564620.015
embryonic organ developmentGO:00485683810.015
response to zinc ionGO:001004360.015
regulation of tyrosine phosphorylation of stat proteinGO:004250910.015
response to bacteriumGO:0009617580.015
regulation of cytokine mediated signaling pathwayGO:000195930.014
homeostasis of number of cells within a tissueGO:004887340.014
ion transmembrane transportGO:0034220910.014
regulation of cell communicationGO:00106462320.014
Mouse
regulation of cell shapeGO:000836010.014
adult behaviorGO:003053420.014
negative regulation of histone modificationGO:003105710.014
regulation of tube sizeGO:003515020.014
biosynthetic processGO:00090582940.014
Human Mouse
striated muscle cell differentiationGO:00511461290.014
regulation of neurological system processGO:003164420.014
female gonad developmentGO:000858540.014
pharyngeal muscle developmentGO:004328240.014
nuclear importGO:005117030.014
muscle organ developmentGO:00075171010.014
regulation of microtubule cytoskeleton organizationGO:007050730.014
Human Mouse
positive regulation of epithelial cell migrationGO:001063420.014
cell projection morphogenesisGO:00488582440.014
negative regulation of cellular component movementGO:0051271180.014
cellular component disassemblyGO:002241110.014
regulation of macromolecule metabolic processGO:00602553170.014
Human Mouse
regulation of locomotionGO:0040012550.014
protein acylationGO:004354330.014
protein import into nucleusGO:000660630.014
regulation of response to stimulusGO:00485832690.014
Human Mouse
regulation of cell deathGO:00109411030.014
Human
cell projection assemblyGO:0030031640.014
neuroblast proliferationGO:000740520.014
regulation of ion transmembrane transporter activityGO:003241220.014
calcium ion transport into cytosolGO:006040230.014
positive regulation of catalytic activityGO:0043085250.014
Mouse
nucleobase containing compound metabolic processGO:00061392740.014
Human Mouse
cell deathGO:00082191210.014
Human
positive regulation of secretionGO:005104710.014
protein destabilizationGO:003164810.014
Mouse
leukocyte differentiationGO:0002521250.013
regulation of protein targetingGO:190353320.013
carbohydrate biosynthetic processGO:001605110.013
axonogenesisGO:00074091520.013
negative regulation of myeloid cell differentiationGO:004563810.013
cation transmembrane transportGO:0098655650.013
positive regulation of nitrogen compound metabolic processGO:0051173690.013
negative regulation of metabolic processGO:0009892860.013
Human Mouse
regulation of blood vessel sizeGO:005088020.013
cellular biosynthetic processGO:00442492860.013
Human Mouse
regulation of transporter activityGO:003240920.013
response to vitaminGO:003327330.013
chordate embryonic developmentGO:00430092710.013
cellular response to external stimulusGO:007149620.013
regulation of cell differentiationGO:00455951420.013
Mouse
negative regulation of epithelial cell proliferationGO:005068010.013
cilium morphogenesisGO:0060271850.013
positive regulation of chromatin modificationGO:190331010.013
centrosome cycleGO:000709810.013
Human Mouse
negative regulation of sequestering of calcium ionGO:005128340.013
regulation of cellular component sizeGO:0032535300.013
cellular response to decreased oxygen levelsGO:003629410.013
nucleic acid metabolic processGO:00903042440.013
Human Mouse
cellular nitrogen compound metabolic processGO:00346412900.013
Human Mouse
regulation of organ growthGO:004662030.013
muscle cell differentiationGO:00426921390.013
positive regulation of cellular amine metabolic processGO:003324000.013
erythrocyte differentiationGO:0030218540.013
regulation of cellular biosynthetic processGO:00313262450.013
Human Mouse
cellular component biogenesisGO:00440851780.013
Human Mouse
histone h3 k9 methylationGO:005156750.013
positive regulation of canonical wnt signaling pathwayGO:009026340.012
positive regulation of epithelial cell differentiationGO:003085820.012
leukocyte homeostasisGO:000177620.012
sarcomere organizationGO:0045214260.012
defense responseGO:0006952470.012
rna metabolic processGO:00160702190.012
Human Mouse
positive regulation of nucleoside metabolic processGO:004597910.012
cellular nitrogen compound biosynthetic processGO:00442712180.012
Human
cellular response to oxygen levelsGO:007145310.012
regulation of neurogenesisGO:0050767870.012
aorta developmentGO:003590440.012
positive regulation of nucleotide catabolic processGO:003081310.012
protein complex disassemblyGO:004324110.012
axon guidanceGO:0007411860.012
gtp catabolic processGO:000618420.012
synaptic growth at neuromuscular junctionGO:005112420.012
post embryonic organ developmentGO:004856940.012
response to endogenous stimulusGO:0009719830.012
guanosine containing compound catabolic processGO:190106920.012
regulation of cell projection assemblyGO:006049140.012
tyrosine phosphorylation of stat proteinGO:000726010.012
lymphocyte differentiationGO:003009890.012
endodermal cell fate determinationGO:000749320.012
keratinocyte differentiationGO:003021600.012
negative regulation of intracellular transportGO:003238730.012
regulation of apoptotic processGO:0042981980.012
Human
muscle tissue developmentGO:00605371100.012
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
regulation of erk1 and erk2 cascadeGO:007037240.012
embryonic hemopoiesisGO:0035162530.011
regulation of rna metabolic processGO:00512522240.011
Human Mouse
positive regulation of small gtpase mediated signal transductionGO:005105710.011
negative regulation of cytokine mediated signaling pathwayGO:000196020.011
zinc ion transmembrane transportGO:007157710.011
protein phosphorylationGO:0006468470.011
Human Mouse
sequestering of calcium ionGO:005120830.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
positive regulation of immune effector processGO:000269930.011
positive regulation of jnk cascadeGO:004633030.011
t cell activationGO:004211060.011
positive regulation of protein complex assemblyGO:003133420.011
regulation of dna templated transcription in response to stressGO:004362000.011
adherens junction assemblyGO:003433310.011
macromolecular complex disassemblyGO:003298410.011
regulation of nucleotide catabolic processGO:003081120.011
response to lipidGO:0033993600.011
muscle cell migrationGO:001481240.011
pericardium developmentGO:006003910.011
regulation of circadian rhythmGO:004275240.011
regulation of catalytic activityGO:0050790550.011
Human Mouse
positive regulation of cellular processGO:00485222010.011
Human Mouse
carbohydrate homeostasisGO:003350010.011
regulation of neurotransmitter transportGO:005158810.011
chemotaxisGO:00069351040.011
homeostasis of number of cellsGO:0048872620.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
spermatid differentiationGO:004851520.011
actin filament polymerizationGO:003004120.011
rna polyadenylationGO:004363120.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
negative regulation of cell differentiationGO:0045596460.011
Mouse
modification dependent protein catabolic processGO:001994130.011
positive regulation of multi organism processGO:004390230.011
regulation of cellular protein catabolic processGO:190336210.011
regulation of nucleocytoplasmic transportGO:004682220.011
regulation of stem cell differentiationGO:200073640.011
odontogenesis of dentin containing toothGO:004247510.011
response to woundingGO:00096111160.011
regulation of myotube differentiationGO:001083020.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
negative regulation of chromatin modificationGO:190330910.011
macromolecule biosynthetic processGO:00090592270.011
Human
heterocycle biosynthetic processGO:00181302150.011
Human
dorsal ventral pattern formationGO:00099531250.011
cartilage developmentGO:0051216960.011
positive regulation of signalingGO:0023056560.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.011
larval developmentGO:000216420.011
phosphatidylinositol mediated signalingGO:004801520.011
positive regulation of jak stat cascadeGO:004642720.010
adherens junction organizationGO:003433240.010
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.010
regulation of epidermis developmentGO:004568220.010
protein o linked glycosylationGO:000649340.010
cranial nerve developmentGO:0021545420.010
epidermal cell fate specificationGO:000995740.010
negative regulation of nucleocytoplasmic transportGO:004682320.010
definitive hemopoiesisGO:0060216180.010
neuron differentiationGO:00301823530.010
somatic muscle developmentGO:000752540.010
ovarian follicle developmentGO:000154120.010
regulation of transcription dna templatedGO:00063552130.010
Human
regulation of protein localization to nucleusGO:190018020.010
regulation of mrna processingGO:005068430.010
Mouse
meiotic nuclear divisionGO:000712640.010
response to uvGO:000941130.010
negative regulation of defense responseGO:003134820.010
regionalizationGO:00030022740.010
phagocytosis engulfmentGO:000691110.010
erk1 and erk2 cascadeGO:007037140.010
ras protein signal transductionGO:000726570.010
positive regulation of reproductive processGO:200024320.010
lymph vessel developmentGO:0001945270.010

npm4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.055
hematopoietic system diseaseDOID:7400.026
bone marrow diseaseDOID:496100.026
immune system diseaseDOID:291400.026
musculoskeletal system diseaseDOID:1700.019
muscular diseaseDOID:008000000.015
muscle tissue diseaseDOID:6600.015
myopathyDOID:42300.015
organ system cancerDOID:005068600.013
Human
leukemiaDOID:124000.013
Human
hematologic cancerDOID:253100.013
Human
immune system cancerDOID:006008300.013
Human
cancerDOID:16200.013
Human
myeloid leukemiaDOID:869200.013
Human
disease of cellular proliferationDOID:1456600.013
Human
anemiaDOID:235500.011
congenital hypoplastic anemiaDOID:134200.011
aplastic anemiaDOID:1244900.011
disease of metabolismDOID:001466700.011
nervous system diseaseDOID:86300.010