Danio rerio

0 known processes

pfn2l

profilin 2 like

(Aliases: wu:fb02e10,zgc:86790,hm:zeh0341,wu:fi35b08)

pfn2l biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pronuclear migrationGO:003504610.675
larval developmentGO:000216420.475
neuron differentiationGO:00301823530.251
heterocycle metabolic processGO:00464832900.251
cell projection organizationGO:00300302840.246
regulation of gene expressionGO:00104682650.245
organic substance biosynthetic processGO:19015762890.225
organic cyclic compound metabolic processGO:19013603010.220
nuclear migrationGO:000709730.219
fertilizationGO:000956630.197
cellular biosynthetic processGO:00442492860.193
cellular component biogenesisGO:00440851780.190
Rat
gene expressionGO:00104672520.181
positive regulation of canonical wnt signaling pathwayGO:009026340.169
biosynthetic processGO:00090582940.153
central nervous system developmentGO:00074173870.152
regulation of metabolic processGO:00192223590.135
macromolecule biosynthetic processGO:00090592270.132
establishment of localizationGO:00512342440.129
autophagyGO:000691440.128
cell morphogenesisGO:00009022890.126
regulation of protein catabolic processGO:004217610.126
negative regulation of biological processGO:00485193040.124
establishment of organelle localizationGO:0051656450.120
nitrogen compound metabolic processGO:00068073190.120
single fertilizationGO:000733830.113
establishment of nucleus localizationGO:004002370.111
regulation of cell differentiationGO:00455951420.110
striated muscle cell differentiationGO:00511461290.109
cellular macromolecule biosynthetic processGO:00346452240.108
cell cycle g2 m phase transitionGO:004483940.107
cytokinesisGO:000091030.100
generation of neuronsGO:00486993850.100
endosomal transportGO:001619720.100
regulation of establishment of protein localizationGO:007020140.096
cytoskeleton dependent cytokinesisGO:006164030.093
protein secretionGO:000930610.093
positive regulation of transportGO:005105020.092
organelle localizationGO:0051640490.088
brain developmentGO:00074202930.086
small molecule metabolic processGO:0044281770.084
head developmentGO:00603223030.084
cortical cytoskeleton organizationGO:003086510.083
cellular component movementGO:00069283350.083
regulation of biosynthetic processGO:00098892500.082
nucleobase containing compound metabolic processGO:00061392740.082
cellular component assemblyGO:00226071700.082
Rat
negative regulation of cellular processGO:00485232830.079
neuron developmentGO:00486662620.078
cell deathGO:00082191210.076
response to external stimulusGO:00096052640.075
signal transductionGO:00071654550.074
taxisGO:00423301090.073
protein localization to plasma membraneGO:007265910.070
regulation of cellular biosynthetic processGO:00313262450.069
growthGO:00400071740.069
apoptotic processGO:00069151160.068
deathGO:00162651210.068
agingGO:000756820.067
cell migrationGO:00164772370.067
cell projection morphogenesisGO:00488582440.067
multi organism processGO:00517041340.066
multicellular organism growthGO:003526440.065
locomotionGO:00400113130.065
muscle structure developmentGO:00610611960.065
programmed cell deathGO:00125011190.064
regulation of cell communicationGO:00106462320.063
positive regulation of biological processGO:00485182530.062
regulation of macromolecule metabolic processGO:00602553170.062
regulation of rna biosynthetic processGO:20011412130.062
regulation of biological qualityGO:00650082630.061
Rat
regulation of nitrogen compound metabolic processGO:00511712510.061
negative regulation of gene expressionGO:0010629650.060
protein metabolic processGO:00195381830.060
ubiquitin dependent protein catabolic processGO:000651130.059
cell surface receptor signaling pathwayGO:00071663250.059
cell morphogenesis involved in neuron differentiationGO:00486671630.058
neuron projection developmentGO:00311751800.058
cellular protein metabolic processGO:00442671290.058
proteolysis involved in cellular protein catabolic processGO:005160330.057
guanosine containing compound metabolic processGO:190106840.057
ribonucleoside monophosphate catabolic processGO:000915840.057
regulation of cell developmentGO:00602841000.056
regionalizationGO:00030022740.056
developmental growthGO:00485891660.056
exocytosisGO:000688710.056
cell part morphogenesisGO:00329902460.056
cellular component morphogenesisGO:00329893360.056
regulation of cytoplasmic transportGO:190364940.055
regulation of cellular metabolic processGO:00313233200.054
regulation of protein transportGO:005122330.053
negative regulation of metabolic processGO:0009892860.052
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.052
guanosine containing compound catabolic processGO:190106920.052
regulation of cellular macromolecule biosynthetic processGO:20001122220.052
cellular protein complex assemblyGO:0043623190.051
Rat
axon developmentGO:00615641660.050
cellular protein catabolic processGO:004425740.050
specification of symmetryGO:00097992040.050
transcription dna templatedGO:00063511810.049
regulation of embryonic developmentGO:0045995470.049
positive regulation of carbohydrate metabolic processGO:004591310.049
positive regulation of secretion by cellGO:190353210.048
negative regulation of cytoplasmic transportGO:190365020.048
positive regulation of catabolic processGO:000989640.048
phagocytosisGO:000690930.048
protein modification by small protein removalGO:007064610.047
regulation of cell shapeGO:000836010.046
positive regulation of cellular component biogenesisGO:004408930.044
gtp metabolic processGO:004603940.044
regulation of developmental processGO:00507932470.044
cellular nitrogen compound biosynthetic processGO:00442712180.043
regulation of cellular carbohydrate metabolic processGO:001067540.042
protein stabilizationGO:005082120.042
regulation of protein ubiquitinationGO:003139630.042
rna metabolic processGO:00160702190.042
axon guidanceGO:0007411860.042
negative regulation of response to stimulusGO:00485851040.042
maintenance of locationGO:005123540.041
regulation of multicellular organismal processGO:00512392770.041
cellular nitrogen compound metabolic processGO:00346412900.041
positive regulation of secretionGO:005104710.041
embryo development ending in birth or egg hatchingGO:00097922710.041
single organism localizationGO:19025782250.040
gtp catabolic processGO:000618420.040
axonogenesisGO:00074091520.039
carbohydrate biosynthetic processGO:001605110.038
rna biosynthetic processGO:00327741810.037
nucleobase containing compound biosynthetic processGO:00346542050.037
cellular macromolecule metabolic processGO:00442603910.037
maternal determination of anterior posterior axis embryoGO:000835840.037
actin polymerization or depolymerizationGO:000815420.037
Rat
sexual reproductionGO:0019953360.037
g2 m transition of mitotic cell cycleGO:000008640.037
regulation of rna metabolic processGO:00512522240.036
negative regulation of cell deathGO:0060548600.036
determination of left right symmetryGO:00073681790.036
catabolic processGO:0009056320.036
protein o linked glycosylationGO:000649340.036
neuron projection regenerationGO:0031102160.035
proteasomal protein catabolic processGO:001049820.035
determination of bilateral symmetryGO:00098552040.035
negative regulation of ras protein signal transductionGO:004658010.035
modification dependent macromolecule catabolic processGO:004363230.035
digestive system developmentGO:00551232890.035
macromolecular complex assemblyGO:0065003350.035
Rat
immune system processGO:00023762410.035
actin filament based movementGO:003004810.034
regulation of chromosome segregationGO:005198310.034
cellular carbohydrate metabolic processGO:004426240.034
response to woundingGO:00096111160.034
negative regulation of multicellular organismal processGO:0051241690.034
negative regulation of signalingGO:0023057960.034
regulation of neurogenesisGO:0050767870.034
nucleoside monophosphate catabolic processGO:000912540.033
tube morphogenesisGO:00352393490.033
regulation of macromolecule biosynthetic processGO:00105562250.033
regulation of gtp catabolic processGO:003312420.033
regulation of nucleobase containing compound metabolic processGO:00192192500.033
carboxylic acid metabolic processGO:0019752220.033
regulation of primary metabolic processGO:00800903110.032
localization of cellGO:00516742440.032
regulation of carbohydrate metabolic processGO:000610940.032
mitotic cytokinesisGO:000028130.032
cellular aromatic compound metabolic processGO:00067252950.032
melanosome localizationGO:0032400210.032
positive regulation of cellular processGO:00485222010.032
centrosome organizationGO:005129710.031
meiotic cell cycle processGO:190304630.031
single organism organelle organizationGO:19025891990.031
Rat
photoreceptor cell outer segment organizationGO:003584590.031
positive regulation of cellular catabolic processGO:003133130.031
cell proliferationGO:0008283800.031
behaviorGO:0007610740.030
translational initiationGO:000641330.030
regulation of cellular ketone metabolic processGO:001056570.030
establishment of localization in cellGO:0051649770.030
cellular amine metabolic processGO:004410620.030
pole plasm assemblyGO:000731540.029
regulation of multicellular organism growthGO:004001440.029
negative regulation of catabolic processGO:000989530.029
heterocycle biosynthetic processGO:00181302150.029
transportGO:00068102200.028
negative regulation of cellular biosynthetic processGO:0031327550.028
chemotaxisGO:00069351040.028
nucleic acid metabolic processGO:00903042440.028
stem cell maintenanceGO:001982740.028
regulation of protein complex assemblyGO:004325430.028
Rat
regulation of nucleoside metabolic processGO:000911820.028
muscle cell differentiationGO:00426921390.028
digestive tract morphogenesisGO:00485462310.028
organic substance catabolic processGO:1901575280.027
cellular component assembly involved in morphogenesisGO:00109271070.027
neurological system processGO:0050877620.027
regulation of nucleic acid templated transcriptionGO:19035062130.027
positive regulation of cytoskeleton organizationGO:005149530.027
nucleus localizationGO:005164780.026
synaptic growth at neuromuscular junctionGO:005112420.026
regulation of neuron differentiationGO:0045664560.026
adult behaviorGO:003053420.026
nucleic acid templated transcriptionGO:00976591810.026
regulation of signal transductionGO:00099662250.025
organonitrogen compound metabolic processGO:1901564740.025
carbohydrate derivative metabolic processGO:1901135610.025
cell substrate adhesionGO:003158940.025
regulation of signalingGO:00230512350.025
regulation of reproductive processGO:200024140.025
macromolecule catabolic processGO:0009057150.025
actin cytoskeleton organizationGO:0030036630.025
Rat
regulation of nervous system developmentGO:0051960900.025
axis specificationGO:0009798430.024
macromolecule glycosylationGO:004341390.024
apoptotic process involved in developmentGO:190274220.024
response to chemicalGO:00422213200.024
purine ribonucleoside monophosphate catabolic processGO:000916940.024
negative regulation of intracellular transportGO:003238730.024
muscle cell developmentGO:00550011150.024
regulation of multicellular organismal developmentGO:20000262230.024
regulation of intracellular protein transportGO:003315730.024
cell motilityGO:00488702440.024
regulation of neuron projection developmentGO:0010975400.023
cellular ketone metabolic processGO:0042180110.023
positive regulation of cellular carbohydrate metabolic processGO:001067610.023
organelle organizationGO:00069962270.023
Rat
carbohydrate homeostasisGO:003350010.023
purine nucleoside monophosphate catabolic processGO:000912840.023
cellular macromolecular complex assemblyGO:0034622240.023
Rat
negative regulation of protein transportGO:005122430.023
positive regulation of translationGO:004572710.023
single organism metabolic processGO:00447102170.023
atp catabolic processGO:000620040.023
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.022
protein modification processGO:00362111000.022
positive regulation of macromolecule metabolic processGO:0010604930.022
macromolecular complex disassemblyGO:003298410.022
system processGO:00030081850.022
embryonic pattern specificationGO:0009880440.022
organic cyclic compound biosynthetic processGO:19013622230.022
cellular response to external stimulusGO:007149620.022
regulation of cellular protein catabolic processGO:190336210.022
cytoplasm organizationGO:000702840.022
mitotic cell cycleGO:0000278640.021
positive regulation of histone modificationGO:003105810.021
single organism cellular localizationGO:1902580460.021
germ line stem cell divisionGO:004207810.021
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.021
protein complex disassemblyGO:004324110.021
cytokinetic processGO:003250620.021
negative regulation of axon regenerationGO:004868140.021
regulation of canonical wnt signaling pathwayGO:0060828340.021
multi organism reproductive processGO:0044703360.021
aromatic compound biosynthetic processGO:00194382170.021
cell cycleGO:0007049930.021
double strand break repairGO:000630230.020
regenerationGO:0031099910.020
morphogenesis of an epitheliumGO:00020093330.020
negative regulation of macromolecule metabolic processGO:0010605760.020
cellular component disassemblyGO:002241110.020
cell cycle processGO:0022402530.020
wnt signaling pathwayGO:0016055800.020
positive regulation of dna metabolic processGO:005105410.020
oocyte anterior posterior axis specificationGO:000731440.020
vasculature developmentGO:00019442780.020
centrosome cycleGO:000709810.019
mitotic dna integrity checkpointGO:004477440.019
macromolecular complex subunit organizationGO:0043933740.019
Rat
actin filament based processGO:0030029640.019
Rat
positive regulation of protein complex assemblyGO:003133420.019
purine nucleotide metabolic processGO:0006163270.019
cellular amino acid metabolic processGO:000652070.019
cell morphogenesis involved in differentiationGO:00009041950.019
mitotic dna damage checkpointGO:004477340.018
actomyosin structure organizationGO:0031032530.018
organelle assemblyGO:00709251100.018
negative regulation of developmental processGO:0051093650.018
organic acid metabolic processGO:0006082310.018
skin developmentGO:0043588540.018
skeletal muscle organ developmentGO:0060538780.018
cellular response to oxygen levelsGO:007145310.018
regulation of cell projection organizationGO:0031344440.017
actin filament polymerizationGO:003004120.017
Rat
positive regulation of cell cycleGO:004578730.017
modification dependent protein catabolic processGO:001994130.017
spermatid differentiationGO:004851520.017
protein complex biogenesisGO:0070271300.017
Rat
purine containing compound metabolic processGO:0072521290.017
myofibril assemblyGO:0030239480.017
plasma membrane repairGO:000177820.017
microtubule organizing center organizationGO:003102310.017
regulation of locomotionGO:0040012550.017
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.017
spermatid developmentGO:000728620.017
single organism transportGO:00447652060.016
myosin filament organizationGO:003103360.016
striated muscle cell developmentGO:00550021080.016
regulation of developmental growthGO:0048638380.016
cellular response to extracellular stimulusGO:003166820.016
meiotic nuclear divisionGO:000712640.016
negative regulation of signal transductionGO:0009968940.016
synaptic vesicle localizationGO:009747910.016
amine metabolic processGO:000930820.016
regulation of cell deathGO:00109411030.016
protein k63 linked ubiquitinationGO:007053420.016
mitotic cell cycle processGO:1903047480.016
vesicle mediated transportGO:0016192220.015
regulation of gtpase activityGO:004308720.015
oxoacid metabolic processGO:0043436310.015
establishment of protein localization to plasma membraneGO:009000210.015
regulation of protein metabolic processGO:0051246560.015
anterior posterior pattern specificationGO:00099521520.015
cranial nerve developmentGO:0021545420.015
regulation of nucleotide catabolic processGO:003081120.015
organism emergence from protective structureGO:007168440.015
regulation of calcium ion dependent exocytosisGO:001715810.015
regulation of protein targetingGO:190353320.015
protein complex localizationGO:003150310.015
negative regulation of chromosome organizationGO:200125110.014
cell matrix adhesionGO:000716040.014
dorsal ventral pattern formationGO:00099531250.014
single organism biosynthetic processGO:0044711710.014
stem cell differentiationGO:00488631170.014
stem cell proliferationGO:007208940.014
glial cell migrationGO:000834730.014
regulation of carbohydrate biosynthetic processGO:004325510.014
protein polyubiquitinationGO:000020940.014
protein localization to nucleusGO:003450430.014
organelle fusionGO:004828430.014
positive regulation of protein polymerizationGO:003227320.014
regulation of circadian rhythmGO:004275240.014
actin filament organizationGO:0007015150.014
Rat
negative regulation of nitrogen compound metabolic processGO:0051172590.014
cellular pigmentationGO:0033059300.014
regulation of apoptotic processGO:0042981980.014
posttranscriptional regulation of gene expressionGO:0010608140.013
regulation of cellular component movementGO:0051270550.013
synaptic vesicle transportGO:004848910.013
cytoskeleton organizationGO:0007010960.013
Rat
protein polymerizationGO:005125840.013
Rat
epithelial cell differentiationGO:00308551160.013
macromolecule modificationGO:00434121110.013
regulation of oocyte developmentGO:006028130.013
neuron projection morphogenesisGO:00488121610.013
ras protein signal transductionGO:000726570.013
neuromuscular process controlling balanceGO:005088530.013
macromolecule localizationGO:0033036540.013
telomere maintenanceGO:000072310.013
epithelial cell developmentGO:0002064420.013
negative regulation of cell communicationGO:0010648960.013
purine ribonucleotide metabolic processGO:0009150270.013
convergent extensionGO:00600261180.013
negative regulation of neuron projection regenerationGO:007057140.013
reproductionGO:0000003400.013
positive regulation of cellular amine metabolic processGO:003324000.013
hatchingGO:003518840.013
regulation of purine nucleotide catabolic processGO:003312120.013
blood vessel morphogenesisGO:00485142160.013
protein importGO:001703830.013
regulation of cell activationGO:005086510.012
positive regulation of chromosome organizationGO:200125210.012
response to external biotic stimulusGO:0043207970.012
response to other organismGO:0051707970.012
cellular response to chemical stimulusGO:00708871570.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
microtubule cytoskeleton organizationGO:0000226330.012
neuroblast proliferationGO:000740520.012
regulation of purine nucleotide metabolic processGO:1900542170.012
heart developmentGO:00075073130.012
sensory perception of painGO:001923310.012
regulation of programmed cell deathGO:00430671010.012
protein complex assemblyGO:0006461300.012
Rat
regulation of cellular component organizationGO:0051128860.012
Rat
calcium ion dependent exocytosisGO:001715610.012
apoptotic process involved in morphogenesisGO:006056120.012
signal transduction in absence of ligandGO:003803410.012
regulation of wnt signaling pathwayGO:0030111530.012
single organism membrane fusionGO:004480120.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
multicellular organism reproductionGO:0032504350.012
regulation of stem cell differentiationGO:200073640.012
regulation of protein modification by small protein conjugation or removalGO:190332030.012
membrane fusionGO:006102520.012
negative regulation of nervous system developmentGO:0051961220.011
embryonic organ developmentGO:00485683810.011
positive regulation of multicellular organismal processGO:0051240520.011
response to stressGO:00069502630.011
cellular macromolecule localizationGO:0070727210.011
developmental programmed cell deathGO:001062340.011
homeostatic processGO:00425921420.011
left right pattern formationGO:0060972190.011
mechanosensory behaviorGO:000763820.011
germ line stem cell maintenanceGO:003071820.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
regulation of protein localization to nucleusGO:190018020.011
regulation of cell cycleGO:0051726520.011
establishment of endothelial barrierGO:006102830.011
regulation of anatomical structure morphogenesisGO:00226031300.011
nucleobase containing small molecule metabolic processGO:0055086320.011
action potentialGO:0001508190.011
digestive tract developmentGO:00485652650.011
golgi vesicle transportGO:004819330.011
positive regulation of wound healingGO:009030310.011
antimicrobial humoral responseGO:001973020.011
ribonucleotide metabolic processGO:0009259270.011
rna localizationGO:000640340.011
regulation of response to stimulusGO:00485832690.011
polarized epithelial cell differentiationGO:003085940.011
regulation of synapse organizationGO:005080730.011
negative regulation of cellular metabolic processGO:0031324770.010
chemosensory behaviorGO:000763510.010
mesoderm developmentGO:0007498880.010
canonical wnt signaling pathwayGO:0060070480.010
response to nutrientGO:000758430.010
adherens junction organizationGO:003433240.010
negative regulation of protein processingGO:0010955100.010
macromolecule deacylationGO:009873230.010
positive regulation of cell adhesionGO:004578510.010
regulation of anatomical structure sizeGO:0090066330.010
Rat
positive regulation of apoptotic signaling pathwayGO:200123510.010
forebrain cell migrationGO:002188510.010
mitotic g2 dna damage checkpointGO:000709530.010
endocytosisGO:0006897160.010
negative regulation of nucleocytoplasmic transportGO:004682320.010
regulation of cellular amino acid metabolic processGO:000652100.010
heterocycle catabolic processGO:0046700150.010

pfn2l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.050
nervous system diseaseDOID:86300.019
organ system cancerDOID:005068600.019
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
sensory system diseaseDOID:005015500.011
eye diseaseDOID:561400.010
eye and adnexa diseaseDOID:149200.010