Danio rerio

0 known processes

ptplb

protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b

(Aliases: zgc:55421,wu:fi32c08)

ptplb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lipid catabolic processGO:001604240.124
maintenance of locationGO:005123540.118
regulation of protein complex assemblyGO:004325430.099
protein polymerizationGO:005125840.093
cellular lipid catabolic processGO:004424230.083
negative regulation of biological processGO:00485193040.067
lipid storageGO:001991510.064
modification dependent protein catabolic processGO:001994130.062
proteolysis involved in cellular protein catabolic processGO:005160330.061
protein polyubiquitinationGO:000020940.060
agingGO:000756820.058
cellular protein catabolic processGO:004425740.057
negative regulation of protein complex assemblyGO:003133310.057
modification dependent macromolecule catabolic processGO:004363230.050
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.048
regulation of protein catabolic processGO:004217610.046
meiotic nuclear divisionGO:000712640.045
positive regulation of catabolic processGO:000989640.044
proteasomal protein catabolic processGO:001049820.042
small molecule metabolic processGO:0044281770.041
actin polymerization or depolymerizationGO:000815420.041
phagocytosisGO:000690930.041
larval developmentGO:000216420.040
Worm
positive regulation of cell cycleGO:004578730.040
fatty acid catabolic processGO:000906210.039
regulation of protein transportGO:005122330.039
nitrogen compound metabolic processGO:00068073190.038
regulation of biological qualityGO:00650082630.038
multicellular organism growthGO:003526440.036
ubiquitin dependent protein catabolic processGO:000651130.036
cellular ketone metabolic processGO:0042180110.035
actin filament polymerizationGO:003004120.035
carboxylic acid catabolic processGO:004639530.033
single organism organelle organizationGO:19025891990.033
regulation of establishment of protein localizationGO:007020140.033
negative regulation of cellular processGO:00485232830.032
response to chemicalGO:00422213200.032
small molecule catabolic processGO:004428230.031
stem cell maintenanceGO:001982740.031
protein complex disassemblyGO:004324110.031
organelle organizationGO:00069962270.031
positive regulation of transportGO:005105020.031
cellular respirationGO:004533330.030
regulation of multicellular organism growthGO:004001440.030
lipid oxidationGO:003444010.030
regulation of carbohydrate metabolic processGO:000610940.030
cellular carbohydrate metabolic processGO:004426240.030
fatty acid beta oxidationGO:000663510.030
regulation of bindingGO:005109830.029
energy reserve metabolic processGO:000611220.029
negative regulation of catabolic processGO:000989530.029
regulation of cellular ketone metabolic processGO:001056570.029
response to organic substanceGO:00100331530.029
cellular component disassemblyGO:002241110.028
protein metabolic processGO:00195381830.028
amine metabolic processGO:000930820.028
monocarboxylic acid catabolic processGO:007232930.028
rna localizationGO:000640340.028
cellular nitrogen compound metabolic processGO:00346412900.027
cellular amine metabolic processGO:004410620.027
regulation of oocyte developmentGO:006028130.026
organic acid metabolic processGO:0006082310.026
regulation of nitrogen compound metabolic processGO:00511712510.026
nucleoside monophosphate catabolic processGO:000912540.026
single organism localizationGO:19025782250.025
Worm
response to stressGO:00069502630.025
single organism metabolic processGO:00447102170.025
regulation of metal ion transportGO:001095940.025
signal transductionGO:00071654550.025
cellular response to external stimulusGO:007149620.025
positive regulation of cellular catabolic processGO:003133130.024
regulation of response to stimulusGO:00485832690.024
response to drugGO:004249330.024
cellular macromolecule biosynthetic processGO:00346452240.024
ribonucleoside monophosphate catabolic processGO:000915840.024
peptidyl threonine phosphorylationGO:001810710.024
regulation of cellular carbohydrate metabolic processGO:001067540.023
protein secretionGO:000930610.023
positive regulation of cellular component biogenesisGO:004408930.023
positive regulation of cytoskeleton organizationGO:005149530.023
cellular component assemblyGO:00226071700.022
biosynthetic processGO:00090582940.022
carboxylic acid metabolic processGO:0019752220.022
heterocycle metabolic processGO:00464832900.022
regulation of reproductive processGO:200024140.022
cellular macromolecule metabolic processGO:00442603910.022
regulation of cellular biosynthetic processGO:00313262450.022
establishment of rna localizationGO:005123630.021
cellular biosynthetic processGO:00442492860.021
oocyte maturationGO:000155640.021
regulation of intracellular protein transportGO:003315730.021
organic substance biosynthetic processGO:19015762890.021
extrinsic apoptotic signaling pathwayGO:009719130.021
rna transportGO:005065820.021
cellular response to chemical stimulusGO:00708871570.021
protein localization to plasma membraneGO:007265910.021
regulation of circadian rhythmGO:004275240.021
cellular response to starvationGO:000926710.021
regulation of cytoplasmic transportGO:190364940.020
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.020
regulation of chromosome segregationGO:005198310.020
protein localization to nucleusGO:003450430.020
cellular nitrogen compound biosynthetic processGO:00442712180.019
regulation of protein complex disassemblyGO:004324410.019
regulation of primary metabolic processGO:00800903110.019
negative regulation of protein phosphorylationGO:000193340.019
oxoacid metabolic processGO:0043436310.019
regulation of cellular protein catabolic processGO:190336210.019
cellular component biogenesisGO:00440851780.019
macromolecular complex disassemblyGO:003298410.019
regulation of cell shapeGO:000836010.019
positive regulation of secretion by cellGO:190353210.019
growthGO:00400071740.019
single organism biosynthetic processGO:0044711710.019
protein importGO:001703830.019
nucleic acid transportGO:005065720.019
response to other organismGO:0051707970.019
protein import into nucleusGO:000660630.018
fatty acid oxidationGO:001939510.018
cellular response to nutrient levelsGO:003166920.018
positive regulation of apoptotic signaling pathwayGO:200123510.018
membrane invaginationGO:001032410.018
deathGO:00162651210.018
regulation of cytokine productionGO:000181730.018
meiosis iGO:000712710.018
regulation of protein ubiquitinationGO:003139630.018
system processGO:00030081850.018
oxidation reduction processGO:0055114410.018
regulation of signalingGO:00230512350.018
purine ribonucleoside monophosphate catabolic processGO:000916940.018
positive regulation of canonical wnt signaling pathwayGO:009026340.018
regulation of cellular amino acid metabolic processGO:000652100.017
regulation of developmental processGO:00507932470.017
regulation of organ growthGO:004662030.017
pronuclear migrationGO:003504610.017
endoplasmic reticulum unfolded protein responseGO:003096820.017
cognitionGO:005089010.017
single organism transportGO:00447652060.017
Worm
lipid metabolic processGO:0006629520.017
cellular protein modification processGO:00064641000.017
response to topologically incorrect proteinGO:003596620.017
organic acid catabolic processGO:001605430.017
nucleocytoplasmic transportGO:000691340.017
regulation of cellular component organizationGO:0051128860.017
purine nucleoside monophosphate catabolic processGO:000912840.017
regulation of organelle assemblyGO:190211540.016
cellular aromatic compound metabolic processGO:00067252950.016
atp catabolic processGO:000620040.016
response to endogenous stimulusGO:0009719830.016
nuclear transportGO:005116940.016
phagocytosis engulfmentGO:000691110.016
germ line stem cell maintenanceGO:003071820.016
guanosine containing compound metabolic processGO:190106840.016
establishment of protein localization to organelleGO:007259440.016
mitotic dna integrity checkpointGO:004477440.016
positive regulation of cell divisionGO:005178120.016
nuclear importGO:005117030.016
regulation of protein polymerizationGO:003227120.016
signal transduction in absence of ligandGO:003803410.016
regulation of gene expressionGO:00104682650.016
gtp metabolic processGO:004603940.015
cellular response to extracellular stimulusGO:003166820.015
regulation of cellular macromolecule biosynthetic processGO:20001122220.015
locomotionGO:00400113130.015
Worm
cellular amino acid metabolic processGO:000652070.015
apoptotic processGO:00069151160.015
nucleobase containing compound transportGO:001593120.015
negative regulation of cellular component organizationGO:0051129160.015
single organism nuclear importGO:190259330.015
negative regulation of chromosome organizationGO:200125110.015
secondary metabolic processGO:001974830.015
cell deathGO:00082191210.015
nucleic acid metabolic processGO:00903042440.015
regulation of metabolic processGO:00192223590.015
cation transmembrane transportGO:0098655650.015
regulation of reactive oxygen species metabolic processGO:200037720.015
heterocycle biosynthetic processGO:00181302150.015
gtp catabolic processGO:000618420.015
nucleobase containing compound metabolic processGO:00061392740.015
tube morphogenesisGO:00352393490.015
nucleobase containing compound biosynthetic processGO:00346542050.015
positive regulation of secretionGO:005104710.015
digestive system developmentGO:00551232890.015
pole plasm assemblyGO:000731540.015
regulation of protein bindingGO:004339330.015
homeostatic processGO:00425921420.015
cation transportGO:0006812810.014
cellular lipid metabolic processGO:0044255360.014
lamellipodium organizationGO:009758110.014
centrosome organizationGO:005129710.014
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.014
programmed cell deathGO:00125011190.014
regulation of multicellular organismal processGO:00512392770.014
regulation of protein depolymerizationGO:190187910.014
cytoskeleton organizationGO:0007010960.014
carbohydrate biosynthetic processGO:001605110.014
regulation of cell communicationGO:00106462320.014
negative regulation of cellular catabolic processGO:003133030.014
regulation of synapse assemblyGO:005196330.014
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.014
regulation of mrna processingGO:005068430.014
stem cell proliferationGO:007208940.014
regulation of biosynthetic processGO:00098892500.014
morphogenesis of an epitheliumGO:00020093330.014
synaptic growth at neuromuscular junctionGO:005112420.014
apoptotic process involved in morphogenesisGO:006056120.014
regulation of nucleocytoplasmic transportGO:004682220.014
regulation of localizationGO:00328791040.014
adherens junction organizationGO:003433240.014
establishment of localizationGO:00512342440.014
Worm
response to external biotic stimulusGO:0043207970.013
fertilizationGO:000956630.013
cell substrate adhesionGO:003158940.013
meiotic chromosome segregationGO:004513230.013
regulation of protein modification by small protein conjugation or removalGO:190332030.013
regulation of cell deathGO:00109411030.013
guanosine containing compound catabolic processGO:190106920.013
regulation of nucleobase containing compound metabolic processGO:00192192500.013
trabecula morphogenesisGO:006138320.013
regulation of cellular metabolic processGO:00313233200.013
regulation of cell maturationGO:190342910.013
peptidyl threonine modificationGO:001821010.013
microtubule organizing center organizationGO:003102310.013
macromolecule biosynthetic processGO:00090592270.013
intracellular signal transductionGO:0035556850.013
protein homooligomerizationGO:005126030.013
single fertilizationGO:000733830.013
macromolecule modificationGO:00434121110.013
regulation of response to biotic stimulusGO:000283120.013
electron transport chainGO:002290020.013
negative regulation of metabolic processGO:0009892860.013
protein stabilizationGO:005082120.013
transmission of nerve impulseGO:0019226190.013
regulation of epithelial cell proliferationGO:005067830.013
meiotic cell cycle processGO:190304630.013
regulation of microtubule cytoskeleton organizationGO:007050730.013
leukocyte proliferationGO:007066110.013
negative regulation of nuclear divisionGO:005178430.013
response to uvGO:000941130.013
long chain fatty acid metabolic processGO:000167610.013
cellular transition metal ion homeostasisGO:004691630.013
cellular response to endogenous stimulusGO:0071495680.013
macromolecular complex assemblyGO:0065003350.013
regulation of cell activationGO:005086510.013
regulation of macromolecule metabolic processGO:00602553170.013
mitotic g2 m transition checkpointGO:004481830.013
somatic muscle developmentGO:000752540.013
developmental maturationGO:0021700340.013
striated muscle cell differentiationGO:00511461290.013
organic cyclic compound metabolic processGO:19013603010.012
transmembrane transportGO:00550851200.012
regulation of protein localization to plasma membraneGO:190307610.012
response to abiotic stimulusGO:00096281220.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
regulation of apoptotic processGO:0042981980.012
regulation of protein import into nucleusGO:004230620.012
regulation of rna metabolic processGO:00512522240.012
gene expressionGO:00104672520.012
respiratory electron transport chainGO:002290420.012
regulation of meiotic cell cycleGO:005144510.012
negative regulation of cytokine productionGO:000181810.012
rna biosynthetic processGO:00327741810.012
nucleic acid templated transcriptionGO:00976591810.012
negative regulation of dna metabolic processGO:005105340.012
positive regulation of ras protein signal transductionGO:004657910.012
protein targeting to nucleusGO:004474430.012
negative regulation of synapse assemblyGO:005196420.012
alcohol biosynthetic processGO:004616520.012
maternal determination of anterior posterior axis embryoGO:000835840.012
cell substrate junction assemblyGO:000704420.012
regulation of response to extracellular stimulusGO:003210410.012
negative regulation of intracellular transportGO:003238730.012
positive regulation of myeloid cell differentiationGO:004563920.012
macromolecule deacylationGO:009873230.012
sensory perception of chemical stimulusGO:000760630.012
cytosolic calcium ion transportGO:006040130.012
membrane fusionGO:006102520.012
cellular macromolecular complex assemblyGO:0034622240.012
regulation of response to nutrient levelsGO:003210710.012
germ line stem cell divisionGO:004207810.012
neuronal action potentialGO:0019228180.012
response to unfolded proteinGO:000698620.012
positive regulation of cellular amine metabolic processGO:003324000.012
cellular amide metabolic processGO:004360340.012
transportGO:00068102200.012
Worm
regulation of protein targetingGO:190353320.012
monoamine transportGO:001584410.012
positive regulation of cell adhesionGO:004578510.012
protein depolymerizationGO:005126110.011
negative regulation of macromolecule metabolic processGO:0010605760.011
cellular response to organic substanceGO:00713101050.011
embryonic organ morphogenesisGO:00485622740.011
developmental programmed cell deathGO:001062340.011
compound eye developmentGO:004874920.011
positive regulation of cell activationGO:005086710.011
aromatic compound biosynthetic processGO:00194382170.011
spindle assemblyGO:005122520.011
negative regulation of reproductive processGO:200024230.011
mitochondrion organizationGO:000700540.011
lateral inhibitionGO:004633110.011
phosphorus metabolic processGO:00067931090.011
mononuclear cell proliferationGO:003294310.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
adult behaviorGO:003053420.011
regulation of cellular amine metabolic processGO:003323800.011
locomotor rhythmGO:004547530.011
regulation of macromolecule biosynthetic processGO:00105562250.011
immune system processGO:00023762410.011
cellular protein metabolic processGO:00442671290.011
cell projection organizationGO:00300302840.011
regulation of calcium ion transportGO:005192420.011
cellular component maintenanceGO:004395430.011
regulation of nucleoside metabolic processGO:000911820.011
regulation of synapse organizationGO:005080730.011
negative regulation of multi organism processGO:004390130.011
regulation of protein localization to nucleusGO:190018020.011
negative regulation of protein transportGO:005122430.011
organelle fusionGO:004828430.011
regulation of mrna splicing via spliceosomeGO:004802430.011
cell morphogenesisGO:00009022890.011
positive regulation of map kinase activityGO:004340630.011
cellular response to biotic stimulusGO:007121630.011
regulation of organelle organizationGO:0033043290.011
multi organism processGO:00517041340.011
positive regulation of protein polymerizationGO:003227320.011
hemopoiesisGO:00300971830.011
cellular response to topologically incorrect proteinGO:003596720.011
response to hexoseGO:000974630.011
regulation of purine nucleotide catabolic processGO:003312120.011
i kappab kinase nf kappab signalingGO:000724940.010
epithelial cell morphogenesisGO:000338220.010
regulation of transcription dna templatedGO:00063552130.010
regulation of membrane potentialGO:0042391230.010
hormone secretionGO:004687920.010
inositol lipid mediated signalingGO:004801720.010
cell proliferationGO:0008283800.010
regulation of transporter activityGO:003240920.010
positive regulation of chromosome organizationGO:200125210.010
positive regulation of nucleotide catabolic processGO:003081310.010
regulation of cell substrate adhesionGO:001081010.010
cell cycle g2 m phase transitionGO:004483940.010
muscle structure developmentGO:00610611960.010
regulation of extrinsic apoptotic signaling pathwayGO:200123630.010
peptide transportGO:001583310.010
stem cell divisionGO:001714510.010
cell cycleGO:0007049930.010
regulation of programmed cell deathGO:00430671010.010
response to biotic stimulusGO:0009607970.010
cranial ganglion developmentGO:006155030.010
tube closureGO:006060610.010
response to corticosteroidGO:003196010.010
chordate embryonic developmentGO:00430092710.010
apoptotic process involved in developmentGO:190274220.010
type b pancreatic cell developmentGO:000332340.010
regulation of wound healingGO:006104120.010
positive regulation of protein complex assemblyGO:003133420.010

ptplb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.039
nervous system diseaseDOID:86300.017
disease of metabolismDOID:001466700.017
musculoskeletal system diseaseDOID:1700.017
cancerDOID:16200.016
disease of cellular proliferationDOID:1456600.016
organ system cancerDOID:005068600.014
inherited metabolic disorderDOID:65500.012