Danio rerio

0 known processes

pus1

pseudouridine synthase 1

(Aliases: zgc:103516,wu:fb98h11)

pus1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.089
agingGO:000756820.053
maintenance of locationGO:005123540.042
cellular macromolecule metabolic processGO:00442603910.042
Yeast
establishment of protein localization to organelleGO:007259440.039
nuclear transportGO:005116940.038
nucleocytoplasmic transportGO:000691340.038
nitrogen compound metabolic processGO:00068073190.037
Yeast
regulation of multicellular organism growthGO:004001440.036
multicellular organism growthGO:003526440.035
proteolysis involved in cellular protein catabolic processGO:005160330.035
gene expressionGO:00104672520.034
Yeast
protein localization to nucleusGO:003450430.033
regulation of macromolecule metabolic processGO:00602553170.033
ubiquitin dependent protein catabolic processGO:000651130.033
cellular nitrogen compound metabolic processGO:00346412900.033
Yeast
regulation of cellular metabolic processGO:00313233200.033
amine metabolic processGO:000930820.032
positive regulation of transportGO:005105020.032
mitochondrion organizationGO:000700540.032
positive regulation of cellular component biogenesisGO:004408930.031
cellular protein catabolic processGO:004425740.031
lipid storageGO:001991510.031
nucleic acid metabolic processGO:00903042440.031
Yeast
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.031
heterocycle metabolic processGO:00464832900.030
Yeast
protein importGO:001703830.030
protein import into nucleusGO:000660630.029
phagocytosisGO:000690930.029
modification dependent protein catabolic processGO:001994130.029
modification dependent macromolecule catabolic processGO:004363230.029
signal transductionGO:00071654550.029
positive regulation of cell cycleGO:004578730.029
organic cyclic compound metabolic processGO:19013603010.029
Yeast
proteasomal protein catabolic processGO:001049820.029
regulation of primary metabolic processGO:00800903110.029
regulation of gene expressionGO:00104682650.029
negative regulation of protein phosphorylationGO:000193340.029
regulation of establishment of protein localizationGO:007020140.028
regulation of metabolic processGO:00192223590.028
autophagyGO:000691440.028
rna metabolic processGO:00160702190.028
Yeast
cellular amine metabolic processGO:004410620.028
nuclear importGO:005117030.028
regulation of mrna processingGO:005068430.027
protein targeting to nucleusGO:004474430.027
regulation of protein catabolic processGO:004217610.027
cognitionGO:005089010.027
cellular aromatic compound metabolic processGO:00067252950.027
Yeast
cellular response to external stimulusGO:007149620.027
single organism nuclear importGO:190259330.027
regulation of biosynthetic processGO:00098892500.027
stem cell maintenanceGO:001982740.026
regulation of protein transportGO:005122330.026
nucleobase containing compound metabolic processGO:00061392740.026
Yeast
macromolecule biosynthetic processGO:00090592270.025
peptidyl lysine acetylationGO:001839420.025
regulation of nitrogen compound metabolic processGO:00511712510.025
regulation of cytokine productionGO:000181730.025
regulation of macromolecule biosynthetic processGO:00105562250.025
regulation of cellular amino acid metabolic processGO:000652100.025
regulation of cellular amine metabolic processGO:003323800.025
regulation of cytoplasmic transportGO:190364940.025
positive regulation of catabolic processGO:000989640.025
biosynthetic processGO:00090582940.024
cytokinesisGO:000091030.024
protein acetylationGO:000647320.024
response to drugGO:004249330.024
cellular response to nutrient levelsGO:003166920.024
regulation of cell activationGO:005086510.024
regulation of response to stimulusGO:00485832690.024
organic substance biosynthetic processGO:19015762890.024
meiotic nuclear divisionGO:000712640.024
regulation of intracellular protein transportGO:003315730.023
regulation of meiotic cell cycleGO:005144510.023
cellular response to extracellular stimulusGO:003166820.023
regulation of mrna splicing via spliceosomeGO:004802430.023
regulation of protein localization to nucleusGO:190018020.023
cellular ketone metabolic processGO:0042180110.023
guanosine containing compound metabolic processGO:190106840.023
single organism metabolic processGO:00447102170.023
regulation of biological qualityGO:00650082630.023
response to chemicalGO:00422213200.023
regulation of cellular ketone metabolic processGO:001056570.023
gtp metabolic processGO:004603940.022
organelle fusionGO:004828430.022
negative regulation of biological processGO:00485193040.022
regulation of signal transductionGO:00099662250.022
extrinsic apoptotic signaling pathwayGO:009719130.022
regulation of autophagyGO:001050630.022
morphogenesis of an epitheliumGO:00020093330.022
regulation of nucleocytoplasmic transportGO:004682220.022
aromatic compound biosynthetic processGO:00194382170.022
generation of neuronsGO:00486993850.022
tube morphogenesisGO:00352393490.022
regulation of protein targetingGO:190353320.022
heterocycle biosynthetic processGO:00181302150.021
regulation of bindingGO:005109830.021
central nervous system developmentGO:00074173870.021
organic cyclic compound biosynthetic processGO:19013622230.021
rna localizationGO:000640340.021
cell surface receptor signaling pathwayGO:00071663250.021
adherens junction organizationGO:003433240.021
female sex differentiationGO:004666040.021
cellular nitrogen compound biosynthetic processGO:00442712180.021
negative regulation of catabolic processGO:000989530.021
response to carbohydrateGO:000974330.021
positive regulation of cellular catabolic processGO:003133130.021
regulation of synapse organizationGO:005080730.021
establishment of localizationGO:00512342440.021
rna biosynthetic processGO:00327741810.020
gtp catabolic processGO:000618420.020
internal protein amino acid acetylationGO:000647520.020
nuclear exportGO:005116810.020
synaptic growth at neuromuscular junctionGO:005112420.020
response to uvGO:000941130.020
protein metabolic processGO:00195381830.020
response to stressGO:00069502630.020
transcription dna templatedGO:00063511810.020
stem cell proliferationGO:007208940.020
regulation of protein import into nucleusGO:004230620.020
immune system processGO:00023762410.020
guanosine containing compound catabolic processGO:190106920.020
cellular biosynthetic processGO:00442492860.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.020
compound eye developmentGO:004874920.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
cellular macromolecule biosynthetic processGO:00346452240.020
purine ribonucleoside monophosphate catabolic processGO:000916940.020
cell substrate adhesionGO:003158940.020
regulation of cell communicationGO:00106462320.019
regulation of metal ion transportGO:001095940.019
regulation of cellular biosynthetic processGO:00313262450.019
cell cycle g1 s phase transitionGO:004484310.019
transportGO:00068102200.019
oxoacid metabolic processGO:0043436310.019
protein acylationGO:004354330.019
cell morphogenesisGO:00009022890.019
digestive system developmentGO:00551232890.019
cellular amino acid metabolic processGO:000652070.019
regulation of nucleobase containing compound metabolic processGO:00192192500.019
neuron differentiationGO:00301823530.019
ribonucleoside monophosphate catabolic processGO:000915840.019
g1 s transition of mitotic cell cycleGO:000008210.019
regulation of protein complex assemblyGO:004325430.019
regulation of protein ubiquitinationGO:003139630.019
regulation of rna metabolic processGO:00512522240.019
cell part morphogenesisGO:00329902460.019
negative regulation of kinase activityGO:003367340.019
cellular component morphogenesisGO:00329893360.019
regulation of cellular macromolecule biosynthetic processGO:20001122220.019
negative regulation of cellular processGO:00485232830.018
single organism membrane fusionGO:004480120.018
internal peptidyl lysine acetylationGO:001839320.018
organic acid catabolic processGO:001605430.018
cell projection morphogenesisGO:00488582440.018
organic acid metabolic processGO:0006082310.018
organonitrogen compound metabolic processGO:1901564740.018
tissue remodelingGO:004877140.018
membrane fusionGO:006102520.018
cellular component movementGO:00069283350.018
negative regulation of protein kinase activityGO:000646940.018
nucleobase containing compound biosynthetic processGO:00346542050.018
embryo development ending in birth or egg hatchingGO:00097922710.018
single organism localizationGO:19025782250.018
regulation of purine nucleotide catabolic processGO:003312120.018
carboxylic acid metabolic processGO:0019752220.018
leukocyte proliferationGO:007066110.018
sensory organ developmentGO:00074233930.018
regulation of neural precursor cell proliferationGO:200017730.018
regulation of nucleoside metabolic processGO:000911820.018
nucleic acid templated transcriptionGO:00976591810.018
regulation of cellular protein catabolic processGO:190336210.018
endosomal transportGO:001619720.018
positive regulation of biological processGO:00485182530.018
regulation of synapse assemblyGO:005196330.018
positive regulation of cell activationGO:005086710.018
meiotic cell cycle processGO:190304630.018
regulation of cell shapeGO:000836010.018
nucleoside monophosphate catabolic processGO:000912540.017
organelle organizationGO:00069962270.017
positive regulation of cellular amine metabolic processGO:003324000.017
regulation of nucleotide catabolic processGO:003081120.017
regulation of signalingGO:00230512350.017
purine nucleoside monophosphate catabolic processGO:000912840.017
cellular component disassemblyGO:002241110.017
microtubule organizing center organizationGO:003102310.017
regionalizationGO:00030022740.017
cellular carbohydrate metabolic processGO:004426240.017
cellular response to starvationGO:000926710.017
cytoskeleton dependent cytokinesisGO:006164030.017
regulation of reproductive processGO:200024140.017
blood vessel developmentGO:00015682460.017
cell projection organizationGO:00300302840.017
regulation of rna biosynthetic processGO:20011412130.017
mitotic dna integrity checkpointGO:004477440.016
regulation of erk1 and erk2 cascadeGO:007037240.016
cellular response to oxygen levelsGO:007145310.016
protein secretionGO:000930610.016
meiotic chromosome segregationGO:004513230.016
regulation of gtp catabolic processGO:003312420.016
cell matrix adhesionGO:000716040.016
cell migrationGO:00164772370.016
atp catabolic processGO:000620040.016
neuron developmentGO:00486662620.016
head developmentGO:00603223030.016
positive regulation of cytokine productionGO:000181920.016
eye developmentGO:00016542770.016
hemopoiesisGO:00300971830.016
positive regulation of dna metabolic processGO:005105410.016
positive regulation of purine nucleotide catabolic processGO:003312310.016
lateral inhibitionGO:004633110.016
vasculature developmentGO:00019442780.016
positive regulation of immune effector processGO:000269930.016
digestive tract morphogenesisGO:00485462310.016
alternative mrna splicing via spliceosomeGO:000038010.016
locomotionGO:00400113130.016
regulation of alternative mrna splicing via spliceosomeGO:000038110.016
positive regulation of secretionGO:005104710.016
erk1 and erk2 cascadeGO:007037140.016
single organism transportGO:00447652060.016
positive regulation of cytoskeleton organizationGO:005149530.016
regulation of stem cell proliferationGO:007209120.016
response to glucoseGO:000974930.016
negative regulation of cellular catabolic processGO:003133030.016
mononuclear cell proliferationGO:003294310.016
viral processGO:001603210.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
regulation of nucleic acid templated transcriptionGO:19035062130.015
fertilizationGO:000956630.015
symbiosis encompassing mutualism through parasitismGO:004440340.015
negative regulation of mapk cascadeGO:004340940.015
female gonad developmentGO:000858540.015
heart developmentGO:00075073130.015
regulation of developmental processGO:00507932470.015
spermatid developmentGO:000728620.015
small molecule metabolic processGO:0044281770.015
spermatid differentiationGO:004851520.015
developmental programmed cell deathGO:001062340.015
i kappab kinase nf kappab signalingGO:000724940.015
positive regulation of protein complex assemblyGO:003133420.015
cellular response to radiationGO:007147840.015
carboxylic acid catabolic processGO:004639530.015
lymphocyte proliferationGO:004665110.015
regulation of inflammatory responseGO:005072720.015
immune system developmentGO:00025201910.015
regulation of sodium ion transportGO:000202820.015
localization of cellGO:00516742440.015
development of primary female sexual characteristicsGO:004654540.015
sequestering of metal ionGO:005123830.015
embryonic organ developmentGO:00485683810.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
secondary metabolic processGO:001974830.015
translational initiationGO:000641330.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
homeostatic processGO:00425921420.015
response to nutrientGO:000758430.015
cellular component biogenesisGO:00440851780.015
positive regulation of nucleotide catabolic processGO:003081310.015
phagocytosis engulfmentGO:000691110.015
adult behaviorGO:003053420.015
blood vessel morphogenesisGO:00485142160.015
response to organic substanceGO:00100331530.015
camera type eye developmentGO:00430102220.014
post embryonic organ developmentGO:004856940.014
locomotor rhythmGO:004547530.014
production of molecular mediator of immune responseGO:000244020.014
centrosome organizationGO:005129710.014
positive regulation of canonical wnt signaling pathwayGO:009026340.014
sequestering of calcium ionGO:005120830.014
somatic muscle developmentGO:000752540.014
cellular protein metabolic processGO:00442671290.014
response to external stimulusGO:00096052640.014
protein localization to plasma membraneGO:007265910.014
regulation of transcription dna templatedGO:00063552130.014
positive regulation of cytosolic calcium ion concentrationGO:000720440.014
positive regulation of cellular processGO:00485222010.014
regulation of gtpase activityGO:004308720.014
protein stabilizationGO:005082120.014
lipid catabolic processGO:001604240.014
positive regulation of secretion by cellGO:190353210.014
membrane invaginationGO:001032410.014
primary neural tube formationGO:001402010.014
positive regulation of gtp catabolic processGO:003312610.014
gastrulationGO:00073692080.014
cellular response to biotic stimulusGO:007121630.014
mitotic dna damage checkpointGO:004477340.014
positive regulation of erk1 and erk2 cascadeGO:007037420.014
nucleic acid transportGO:005065720.014
macromolecule modificationGO:00434121110.014
Yeast
protein heterooligomerizationGO:005129110.014
regulation of transporter activityGO:003240920.014
regulation of multicellular organismal processGO:00512392770.014
regulation of sequestering of calcium ionGO:005128240.014
release of sequestered calcium ion into cytosolGO:005120930.014
regulation of dna replicationGO:000627530.014
positive regulation of nucleoside metabolic processGO:004597910.014
convergent extensionGO:00600261180.014
negative regulation of cytokine productionGO:000181810.014
negative regulation of sequestering of calcium ionGO:005128340.014
exocytosisGO:000688710.014
positive regulation of gtpase activityGO:004354710.014
single organism organelle organizationGO:19025891990.014
protein homooligomerizationGO:005126030.014
glucose homeostasisGO:004259310.014
mitotic cell cycle embryonicGO:004544820.014
golgi vesicle transportGO:004819330.013
transcription from rna polymerase ii promoterGO:0006366800.013
brain developmentGO:00074202930.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
regulation of response to biotic stimulusGO:000283120.013
peptidyl serine modificationGO:001820920.013
peptidyl serine phosphorylationGO:001810510.013
single fertilizationGO:000733830.013
cellular component assemblyGO:00226071700.013
cellular amide metabolic processGO:004360340.013
double strand break repairGO:000630230.013
cell motilityGO:00488702440.013
germ line stem cell maintenanceGO:003071820.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
small molecule catabolic processGO:004428230.013
protein polyubiquitinationGO:000020940.013
intracellular signal transductionGO:0035556850.013
cellular response to chemical stimulusGO:00708871570.013
peptide transportGO:001583310.013
regulation of multicellular organismal developmentGO:20000262230.013
cellular response to light stimulusGO:007148240.013
negative regulation of nuclear divisionGO:005178430.013
macromolecular complex disassemblyGO:003298410.013
growthGO:00400071740.013
signal transduction in absence of ligandGO:003803410.013
carbohydrate homeostasisGO:003350010.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.013
negative regulation of protein transportGO:005122430.013
angiogenesisGO:00015251580.013
lipid homeostasisGO:005508830.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
calcium ion transport into cytosolGO:006040230.013
system processGO:00030081850.013
chordate embryonic developmentGO:00430092710.013
protein complex disassemblyGO:004324110.013
regulation of dna templated transcription elongationGO:003278430.013
regulation of calcium ion transportGO:005192420.013
rna transportGO:005065820.013
multicellular organismal metabolic processGO:004423620.013
interspecies interaction between organismsGO:004441940.013
dorsal ventral pattern formationGO:00099531250.013
regulation of blood pressureGO:000821710.013
protein dephosphorylationGO:000647030.013
cytosolic calcium ion transportGO:006040130.013
chemosensory behaviorGO:000763510.012
establishment of rna localizationGO:005123630.012
mitochondrial transportGO:000683920.012
nucleobase containing compound transportGO:001593120.012
regulation of production of molecular mediator of immune responseGO:000270010.012
rna 3 end processingGO:003112320.012
positive regulation of chromatin modificationGO:190331010.012
developmental growthGO:00485891660.012
sensory organ morphogenesisGO:00905962000.012
multi organism cellular processGO:004476420.012
regulation of jak stat cascadeGO:004642530.012
actin polymerization or depolymerizationGO:000815420.012
neuroblast proliferationGO:000740520.012
regulation of epithelial cell proliferationGO:005067830.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.012
cellular response to molecule of bacterial originGO:007121930.012
positive regulation of chromosome organizationGO:200125210.012
negative regulation of macromolecule metabolic processGO:0010605760.012
negative regulation of metabolic processGO:0009892860.012
negative regulation of ras protein signal transductionGO:004658010.012
dna templated transcription elongationGO:000635430.012
stem cell divisionGO:001714510.012
negative regulation of cytoplasmic transportGO:190365020.012
retina development in camera type eyeGO:00600411460.012
regulation of cell substrate adhesionGO:001081010.012
somatic stem cell maintenanceGO:003501910.012
negative regulation of nucleocytoplasmic transportGO:004682320.012
negative regulation of defense responseGO:003134820.012
b cell activationGO:004211320.012
response to monosaccharideGO:003428430.012
deathGO:00162651210.012
regulation of organ growthGO:004662030.011
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.011
g2 dna damage checkpointGO:003157230.011
tube closureGO:006060610.011
specification of symmetryGO:00097992040.011
toll like receptor signaling pathwayGO:000222440.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
cell deathGO:00082191210.011
ovulation cycle processGO:002260220.011
apoptotic processGO:00069151160.011
cellular protein modification processGO:00064641000.011
regulation of transmembrane transporter activityGO:002289820.011
cell morphogenesis involved in differentiationGO:00009041950.011
mitotic cytokinesisGO:000028130.011
positive regulation of epithelial cell proliferationGO:005067910.011
amino acid transportGO:000686520.011
negative regulation of protein import into nucleusGO:004230820.011
negative regulation of intracellular transportGO:003238730.011
antimicrobial humoral responseGO:001973020.011
response to corticosteroidGO:003196010.011
cilium morphogenesisGO:0060271850.011
sleepGO:003043110.011
regulation of carbohydrate metabolic processGO:000610940.011
response to alkaloidGO:004327920.011
positive regulation of cell divisionGO:005178120.011
hormone secretionGO:004687920.011
digestive tract developmentGO:00485652650.011
cellular response to hypoxiaGO:007145610.011
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.011
eye morphogenesisGO:00485921440.011
neurotransmitter transportGO:000683620.011
actin filament polymerizationGO:003004120.011
neuron neuron synaptic transmissionGO:000727010.011
protein modification processGO:00362111000.011
regulation of ion transmembrane transporter activityGO:003241220.011
peptide metabolic processGO:000651810.011
cellular lipid catabolic processGO:004424230.011
determination of left right symmetryGO:00073681790.011
muscle structure developmentGO:00610611960.011
regulation of circadian rhythmGO:004275240.011
negative regulation of protein localization to nucleusGO:190018120.011
positive regulation of cell adhesionGO:004578510.011
programmed cell deathGO:00125011190.011
determination of bilateral symmetryGO:00098552040.011
cell cycle arrestGO:000705010.011
ameboidal type cell migrationGO:00016671430.011
macroautophagyGO:001623610.011
rna modificationGO:000945120.011
Yeast
regulation of dendrite developmentGO:005077330.011
cellular response to decreased oxygen levelsGO:003629410.011
positive regulation of translationGO:004572710.011
negative regulation of gene expressionGO:0010629650.011
lipid oxidationGO:003444010.011
negative regulation of rna splicingGO:003311910.011
response to topologically incorrect proteinGO:003596620.011
monocarboxylic acid catabolic processGO:007232930.011
regulation of chromosome segregationGO:005198310.011
positive regulation of protein polymerizationGO:003227320.011
positive regulation of neuron apoptotic processGO:004352510.011
mitotic g2 dna damage checkpointGO:000709530.011
cellular localizationGO:0051641970.011
cellular respirationGO:004533330.010
regulation of extrinsic apoptotic signaling pathwayGO:200123630.010
phosphatidylinositol mediated signalingGO:004801520.010
regulation of dna templated transcription in response to stressGO:004362000.010
regulation of wound healingGO:006104120.010
myeloid cell differentiationGO:0030099860.010
negative regulation of intracellular protein transportGO:009031730.010
cell substrate junction assemblyGO:000704420.010
axonogenesisGO:00074091520.010
negative regulation of small gtpase mediated signal transductionGO:005105810.010
regulation of stem cell differentiationGO:200073640.010
positive regulation of histone modificationGO:003105810.010
peptidyl threonine phosphorylationGO:001810710.010
glial cell migrationGO:000834730.010
negative regulation of nitrogen compound metabolic processGO:0051172590.010
negative regulation of map kinase activityGO:004340720.010
anterior posterior pattern specificationGO:00099521520.010
embryonic organ morphogenesisGO:00485622740.010
centrosome duplicationGO:005129810.010
negative regulation of mitosisGO:004583930.010
osteoclast differentiationGO:003031610.010
telomere maintenanceGO:000072310.010
regulation of neurotransmitter secretionGO:004692810.010
er to golgi vesicle mediated transportGO:000688810.010
response to woundingGO:00096111160.010
immunoglobulin mediated immune responseGO:001606430.010
cellular response to organic substanceGO:00713101050.010
inositol lipid mediated signalingGO:004801720.010
b cell mediated immunityGO:001972430.010
meiosis iGO:000712710.010
neuron projection morphogenesisGO:00488121610.010
negative regulation of secretionGO:005104820.010
phosphate containing compound metabolic processGO:00067961080.010
negative regulation of multi organism processGO:004390130.010
positive regulation of lymphocyte mediated immunityGO:000270810.010

pus1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
musculoskeletal system diseaseDOID:1700.022
cancerDOID:16200.019
disease of cellular proliferationDOID:1456600.019
organ system cancerDOID:005068600.019
nervous system diseaseDOID:86300.018
disease of metabolismDOID:001466700.018
immune system diseaseDOID:291400.017
muscular diseaseDOID:008000000.013
sensory system diseaseDOID:005015500.013
eye and adnexa diseaseDOID:149200.013
eye diseaseDOID:561400.013
myopathyDOID:42300.012
muscle tissue diseaseDOID:6600.012
inherited metabolic disorderDOID:65500.012
cardiovascular system diseaseDOID:128700.011