Danio rerio

0 known processes

ercc8

excision repair cross-complementing rodent repair deficiency, complementation group 8

(Aliases: zgc:103550)

ercc8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.077
agingGO:000756820.056
nitrogen compound metabolic processGO:00068073190.045
Human
positive regulation of transportGO:005105020.045
proteolysis involved in cellular protein catabolic processGO:005160330.044
Human
cellular macromolecule metabolic processGO:00442603910.042
Human
maintenance of locationGO:005123540.041
establishment of protein localization to organelleGO:007259440.039
cellular nitrogen compound metabolic processGO:00346412900.038
Human
proteasomal protein catabolic processGO:001049820.035
Human
negative regulation of protein phosphorylationGO:000193340.035
signal transductionGO:00071654550.035
cellular protein catabolic processGO:004425740.034
Human
single organism metabolic processGO:00447102170.034
Human
nuclear transportGO:005116940.034
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.033
Human
regulation of multicellular organism growthGO:004001440.033
amine metabolic processGO:000930820.033
modification dependent protein catabolic processGO:001994130.032
Human
regulation of metabolic processGO:00192223590.032
Human
multicellular organism growthGO:003526440.032
regulation of establishment of protein localizationGO:007020140.032
autophagyGO:000691440.031
nucleocytoplasmic transportGO:000691340.031
positive regulation of catabolic processGO:000989640.031
regulation of protein transportGO:005122330.031
meiotic nuclear divisionGO:000712640.030
positive regulation of cell cycleGO:004578730.030
ubiquitin dependent protein catabolic processGO:000651130.030
Human
protein localization to nucleusGO:003450430.030
regulation of cytokine productionGO:000181730.029
modification dependent macromolecule catabolic processGO:004363230.029
Human
regulation of autophagyGO:001050630.029
mitochondrion organizationGO:000700540.029
protein importGO:001703830.029
positive regulation of cellular catabolic processGO:003133130.028
organic cyclic compound metabolic processGO:19013603010.028
Human
cellular aromatic compound metabolic processGO:00067252950.028
Human
regulation of cellular metabolic processGO:00313233200.028
Human
single organism nuclear importGO:190259330.028
protein acetylationGO:000647320.027
phagocytosisGO:000690930.027
organic substance biosynthetic processGO:19015762890.027
guanosine containing compound catabolic processGO:190106920.027
cognitionGO:005089010.026
negative regulation of biological processGO:00485193040.026
heterocycle metabolic processGO:00464832900.026
Human
cellular amine metabolic processGO:004410620.026
guanosine containing compound metabolic processGO:190106840.026
cellular response to external stimulusGO:007149620.026
cellular response to nutrient levelsGO:003166920.026
lipid storageGO:001991510.026
regulation of cellular amino acid metabolic processGO:000652100.025
gtp metabolic processGO:004603940.025
regulation of nitrogen compound metabolic processGO:00511712510.025
Human
cellular response to extracellular stimulusGO:003166820.025
regulation of gene expressionGO:00104682650.025
nucleobase containing compound metabolic processGO:00061392740.025
Human
regulation of cellular amine metabolic processGO:003323800.025
regulation of cytoplasmic transportGO:190364940.025
protein targeting to nucleusGO:004474430.025
extrinsic apoptotic signaling pathwayGO:009719130.025
response to drugGO:004249330.025
response to stressGO:00069502630.025
Human
regulation of protein localization to nucleusGO:190018020.024
nucleic acid metabolic processGO:00903042440.024
Human
nuclear importGO:005117030.024
response to chemicalGO:00422213200.024
gene expressionGO:00104672520.024
cellular biosynthetic processGO:00442492860.024
protein import into nucleusGO:000660630.024
organonitrogen compound metabolic processGO:1901564740.024
gtp catabolic processGO:000618420.024
rna metabolic processGO:00160702190.024
regulation of mrna processingGO:005068430.023
regulation of intracellular protein transportGO:003315730.023
peptidyl lysine acetylationGO:001839420.023
biosynthetic processGO:00090582940.023
regulation of protein targetingGO:190353320.023
regulation of meiotic cell cycleGO:005144510.023
positive regulation of cellular component biogenesisGO:004408930.023
atp catabolic processGO:000620040.023
ribonucleoside monophosphate catabolic processGO:000915840.023
regulation of protein catabolic processGO:004217610.023
regulation of nucleocytoplasmic transportGO:004682220.023
cellular macromolecule biosynthetic processGO:00346452240.022
synaptic growth at neuromuscular junctionGO:005112420.022
cell surface receptor signaling pathwayGO:00071663250.022
regulation of metal ion transportGO:001095940.022
regulation of primary metabolic processGO:00800903110.022
Human
cellular ketone metabolic processGO:0042180110.022
single organism localizationGO:19025782250.022
regulation of nucleotide catabolic processGO:003081120.022
generation of neuronsGO:00486993850.022
small molecule metabolic processGO:0044281770.022
aromatic compound biosynthetic processGO:00194382170.022
female sex differentiationGO:004666040.022
immune system processGO:00023762410.022
purine ribonucleoside monophosphate catabolic processGO:000916940.022
nucleoside monophosphate catabolic processGO:000912540.022
regulation of bindingGO:005109830.021
organic acid metabolic processGO:0006082310.021
heterocycle biosynthetic processGO:00181302150.021
internal protein amino acid acetylationGO:000647520.021
rna localizationGO:000640340.021
internal peptidyl lysine acetylationGO:001839320.021
response to monosaccharideGO:003428430.021
morphogenesis of an epitheliumGO:00020093330.021
oxoacid metabolic processGO:0043436310.021
meiotic chromosome segregationGO:004513230.021
meiotic cell cycle processGO:190304630.021
positive regulation of secretionGO:005104710.021
cellular nitrogen compound biosynthetic processGO:00442712180.021
regulation of cellular ketone metabolic processGO:001056570.021
regulation of protein import into nucleusGO:004230620.021
tissue remodelingGO:004877140.021
single organism membrane fusionGO:004480120.021
organic cyclic compound biosynthetic processGO:19013622230.021
protein acylationGO:004354330.020
regulation of protein ubiquitinationGO:003139630.020
carboxylic acid metabolic processGO:0019752220.020
regulation of reproductive processGO:200024140.020
negative regulation of protein kinase activityGO:000646940.020
cytokinesisGO:000091030.020
regulation of macromolecule metabolic processGO:00602553170.020
Human
negative regulation of kinase activityGO:003367340.020
tube morphogenesisGO:00352393490.020
i kappab kinase nf kappab signalingGO:000724940.020
stem cell maintenanceGO:001982740.020
regulation of cell activationGO:005086510.020
regulation of synapse assemblyGO:005196330.020
erk1 and erk2 cascadeGO:007037140.020
regulation of biosynthetic processGO:00098892500.020
leukocyte proliferationGO:007066110.020
regulation of response to stimulusGO:00485832690.020
Human
regulation of purine nucleotide catabolic processGO:003312120.020
regulation of nucleoside metabolic processGO:000911820.020
membrane fusionGO:006102520.020
regulation of biological qualityGO:00650082630.019
cell substrate adhesionGO:003158940.019
organelle organizationGO:00069962270.019
protein metabolic processGO:00195381830.019
Human
regulation of multicellular organismal processGO:00512392770.019
regulation of protein modification by small protein conjugation or removalGO:190332030.019
locomotionGO:00400113130.019
negative regulation of cellular processGO:00485232830.019
g1 s transition of mitotic cell cycleGO:000008210.019
sensory organ developmentGO:00074233930.019
regulation of neural precursor cell proliferationGO:200017730.019
regulation of synapse organizationGO:005080730.019
response to uvGO:000941130.019
Human Mouse
regulation of nucleobase containing compound metabolic processGO:00192192500.019
Human
mononuclear cell proliferationGO:003294310.019
cellular component movementGO:00069283350.018
cellular response to biotic stimulusGO:007121630.018
cellular component disassemblyGO:002241110.018
positive regulation of biological processGO:00485182530.018
Human
cell cycle g1 s phase transitionGO:004484310.018
regulation of cellular biosynthetic processGO:00313262450.018
symbiosis encompassing mutualism through parasitismGO:004440340.018
cellular amino acid metabolic processGO:000652070.018
secondary metabolic processGO:001974830.018
regulation of cell communicationGO:00106462320.018
positive regulation of purine nucleotide catabolic processGO:003312310.018
mitotic dna integrity checkpointGO:004477440.018
cell part morphogenesisGO:00329902460.018
macromolecule biosynthetic processGO:00090592270.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.018
response to external stimulusGO:00096052640.018
purine nucleoside monophosphate catabolic processGO:000912840.018
cellular response to starvationGO:000926710.018
positive regulation of cellular amine metabolic processGO:003324000.018
single organism organelle organizationGO:19025891990.018
endosomal transportGO:001619720.018
neuron differentiationGO:00301823530.018
transcription dna templatedGO:00063511810.018
negative regulation of catabolic processGO:000989530.017
regulation of signal transductionGO:00099662250.017
cellular component morphogenesisGO:00329893360.017
positive regulation of secretion by cellGO:190353210.017
regulation of mrna splicing via spliceosomeGO:004802430.017
regulation of signalingGO:00230512350.017
exocytosisGO:000688710.017
response to carbohydrateGO:000974330.017
establishment of localizationGO:00512342440.017
regulation of stem cell differentiationGO:200073640.017
regulation of i kappab kinase nf kappab signalingGO:004312240.017
developmental programmed cell deathGO:001062340.017
positive regulation of immune effector processGO:000269930.017
regulation of erk1 and erk2 cascadeGO:007037240.017
organelle fusionGO:004828430.017
regulation of gtp catabolic processGO:003312420.017
positive regulation of nucleoside metabolic processGO:004597910.017
nucleobase containing compound biosynthetic processGO:00346542050.017
single organism transportGO:00447652060.017
positive regulation of cytokine productionGO:000181920.016
adult behaviorGO:003053420.016
positive regulation of cellular processGO:00485222010.016
Human
negative regulation of mapk cascadeGO:004340940.016
lateral inhibitionGO:004633110.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
cell morphogenesisGO:00009022890.016
protein secretionGO:000930610.016
production of molecular mediator of immune responseGO:000244020.016
positive regulation of dna metabolic processGO:005105410.016
Human
b cell activationGO:004211320.016
cell migrationGO:00164772370.016
positive regulation of nucleotide catabolic processGO:003081310.016
small molecule catabolic processGO:004428230.016
lymphocyte proliferationGO:004665110.016
positive regulation of cell activationGO:005086710.016
regulation of sequestering of calcium ionGO:005128240.016
regulation of reactive oxygen species metabolic processGO:200037720.016
nucleic acid templated transcriptionGO:00976591810.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
negative regulation of cellular catabolic processGO:003133030.016
compound eye developmentGO:004874920.016
sequestering of calcium ionGO:005120830.016
heart developmentGO:00075073130.016
cellular protein metabolic processGO:00442671290.016
Human
regulation of cell shapeGO:000836010.016
regulation of calcium ion transportGO:005192420.016
interspecies interaction between organismsGO:004441940.016
organic acid catabolic processGO:001605430.016
localization of cellGO:00516742440.016
peptidyl serine phosphorylationGO:001810510.016
mitotic dna damage checkpointGO:004477340.016
regulation of alternative mrna splicing via spliceosomeGO:000038110.016
regulation of multicellular organismal developmentGO:20000262230.016
regulation of dna replicationGO:000627530.016
transportGO:00068102200.016
positive regulation of gtp catabolic processGO:003312610.015
rna biosynthetic processGO:00327741810.015
regulation of macromolecule biosynthetic processGO:00105562250.015
negative regulation of nuclear divisionGO:005178430.015
regulation of production of molecular mediator of immune responseGO:000270010.015
negative regulation of cytoplasmic transportGO:190365020.015
system processGO:00030081850.015
primary neural tube formationGO:001402010.015
adherens junction organizationGO:003433240.015
protein localization to plasma membraneGO:007265910.015
development of primary female sexual characteristicsGO:004654540.015
sequestering of metal ionGO:005123830.015
head developmentGO:00603223030.015
cellular amide metabolic processGO:004360340.015
digestive system developmentGO:00551232890.015
negative regulation of cytokine productionGO:000181810.015
regulation of cellular protein catabolic processGO:190336210.015
regulation of rna biosynthetic processGO:20011412130.015
cell projection morphogenesisGO:00488582440.015
eye developmentGO:00016542770.015
stem cell proliferationGO:007208940.015
cellular response to radiationGO:007147840.015
glucose homeostasisGO:004259310.015
mitochondrial transportGO:000683920.015
digestive tract morphogenesisGO:00485462310.015
lipid catabolic processGO:001604240.015
female gonad developmentGO:000858540.015
regulation of gtpase activityGO:004308720.015
central nervous system developmentGO:00074173870.015
membrane invaginationGO:001032410.015
rna 3 end processingGO:003112320.015
intracellular signal transductionGO:0035556850.015
double strand break repairGO:000630230.015
cell matrix adhesionGO:000716040.015
response to hexoseGO:000974630.015
negative regulation of protein transportGO:005122430.015
regulation of response to biotic stimulusGO:000283120.015
negative regulation of sequestering of calcium ionGO:005128340.015
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.015
response to glucoseGO:000974930.015
positive regulation of protein complex assemblyGO:003133420.015
nucleic acid transportGO:005065720.015
regulation of cellular macromolecule biosynthetic processGO:20001122220.015
cellular response to chemical stimulusGO:00708871570.015
centrosome cycleGO:000709810.015
regulation of rna metabolic processGO:00512522240.015
peptidyl serine modificationGO:001820920.015
regulation of protein complex assemblyGO:004325430.014
cellular component assemblyGO:00226071700.014
response to nutrientGO:000758430.014
cellular response to oxygen levelsGO:007145310.014
signal transduction in absence of ligandGO:003803410.014
peptide transportGO:001583310.014
homeostatic processGO:00425921420.014
carboxylic acid catabolic processGO:004639530.014
positive regulation of gtpase activityGO:004354710.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
response to organic substanceGO:00100331530.014
cellular response to lipopolysaccharideGO:007122230.014
establishment of protein localization to plasma membraneGO:009000210.014
nuclear exportGO:005116810.014
regulation of synaptic plasticityGO:004816710.014
positive regulation of erk1 and erk2 cascadeGO:007037420.014
vasculature developmentGO:00019442780.014
cell projection organizationGO:00300302840.014
protein complex disassemblyGO:004324110.014
cellular response to molecule of bacterial originGO:007121930.014
alternative mrna splicing via spliceosomeGO:000038010.014
positive regulation of cytosolic calcium ion concentrationGO:000720440.014
regulation of transcription dna templatedGO:00063552130.014
nucleobase containing compound transportGO:001593120.014
digestive tract developmentGO:00485652650.014
positive regulation of i kappab kinase nf kappab signalingGO:004312330.014
phosphorus metabolic processGO:00067931090.013
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.013
lipid homeostasisGO:005508830.013
viral processGO:001603210.013
gastrulationGO:00073692080.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
immune system developmentGO:00025201910.013
peptide metabolic processGO:000651810.013
positive regulation of chromosome organizationGO:200125210.013
single fertilizationGO:000733830.013
dna templated transcription elongationGO:000635430.013
regulation of developmental processGO:00507932470.013
positive regulation of translationGO:004572710.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.013
regulation of extrinsic apoptotic signaling pathwayGO:200123630.013
cellular carbohydrate metabolic processGO:004426240.013
growthGO:00400071740.013
regulation of inflammatory responseGO:005072720.013
positive regulation of stress activated mapk cascadeGO:003287430.013
locomotor rhythmGO:004547530.013
toll like receptor signaling pathwayGO:000222440.013
fertilizationGO:000956630.013
embryonic organ developmentGO:00485683810.013
positive regulation of jnk cascadeGO:004633030.013
cellular component biogenesisGO:00440851780.013
antimicrobial humoral responseGO:001973020.013
chordate embryonic developmentGO:00430092710.013
phagocytosis engulfmentGO:000691110.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
cellular lipid catabolic processGO:004424230.013
protein polyubiquitinationGO:000020940.013
Human
spermatid developmentGO:000728620.013
regulation of ion transmembrane transporter activityGO:003241220.013
neuron developmentGO:00486662620.013
regulation of organ growthGO:004662030.013
hormone secretionGO:004687920.013
carbohydrate homeostasisGO:003350010.013
positive regulation of chromatin modificationGO:190331010.013
lipid oxidationGO:003444010.013
cytoskeleton dependent cytokinesisGO:006164030.013
cell motilityGO:00488702440.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
negative regulation of metabolic processGO:0009892860.013
blood vessel developmentGO:00015682460.013
regulation of rho protein signal transductionGO:003502320.013
centrosome organizationGO:005129710.013
negative regulation of protein import into nucleusGO:004230820.013
rna transportGO:005065820.013
protein stabilizationGO:005082120.013
double strand break repair via homologous recombinationGO:000072410.013
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
Human
post embryonic organ developmentGO:004856940.012
muscle structure developmentGO:00610611960.012
negative regulation of protein localization to nucleusGO:190018120.012
rna modificationGO:000945120.012
monocarboxylic acid catabolic processGO:007232930.012
spermatid differentiationGO:004851520.012
rna export from nucleusGO:000640510.012
regulation of stem cell proliferationGO:007209120.012
regulation of transporter activityGO:003240920.012
golgi vesicle transportGO:004819330.012
ion transportGO:00068111140.012
transcription from rna polymerase ii promoterGO:0006366800.012
negative regulation of intracellular transportGO:003238730.012
microtubule organizing center organizationGO:003102310.012
protein homooligomerizationGO:005126030.012
transcription elongation from rna polymerase ii promoterGO:000636830.012
regulation of dna templated transcription elongationGO:003278430.012
negative regulation of defense responseGO:003134820.012
tube closureGO:006060610.012
protein modification processGO:00362111000.012
Human
peptidyl threonine phosphorylationGO:001810710.012
cellular response to light stimulusGO:007148240.012
response to alkaloidGO:004327920.012
meiosis iGO:000712710.012
positive regulation of cytoskeleton organizationGO:005149530.012
macromolecular complex disassemblyGO:003298410.012
negative regulation of nucleocytoplasmic transportGO:004682320.012
regulation of dendrite developmentGO:005077330.012
phosphate containing compound metabolic processGO:00067961080.012
protein dephosphorylationGO:000647030.012
cytosolic calcium ion transportGO:006040130.012
response to corticosteroidGO:003196010.012
macroautophagyGO:001623610.012
apoptotic process involved in developmentGO:190274220.012
negative regulation of secretion by cellGO:190353120.012
multi organism processGO:00517041340.012
retina development in camera type eyeGO:00600411460.012
phosphatidylinositol mediated signalingGO:004801520.012
regulation of neurotransmitter transportGO:005158810.012
intracellular mrna localizationGO:000829810.012
cellular protein modification processGO:00064641000.012
Human
establishment of rna localizationGO:005123630.012
regulation of jak stat cascadeGO:004642530.012
multi organism cellular processGO:004476420.012
blood vessel morphogenesisGO:00485142160.012
negative regulation of map kinase activityGO:004340720.012
g2 dna damage checkpointGO:003157230.011
regulation of transmembrane transporter activityGO:002289820.011
calcium ion transport into cytosolGO:006040230.011
cell cycle arrestGO:000705010.011
regulation of epithelial cell proliferationGO:005067830.011
germ line stem cell maintenanceGO:003071820.011
release of sequestered calcium ion into cytosolGO:005120930.011
positive regulation of lymphocyte mediated immunityGO:000270810.011
cellular response to organic substanceGO:00713101050.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
maternal determination of anterior posterior axis embryoGO:000835840.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
convergent extensionGO:00600261180.011
positive regulation of canonical wnt signaling pathwayGO:009026340.011
angiogenesisGO:00015251580.011
negative regulation of secretionGO:005104820.011
protein heterooligomerizationGO:005129110.011
macromolecule modificationGO:00434121110.011
Human
specification of symmetryGO:00097992040.011
negative regulation of ras protein signal transductionGO:004658010.011
hemopoiesisGO:00300971830.011
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.011
oocyte anterior posterior axis specificationGO:000731440.011
developmental growthGO:00485891660.011
camera type eye developmentGO:00430102220.011
response to topologically incorrect proteinGO:003596620.011
cell deathGO:00082191210.011
sleepGO:003043110.011
chemosensory behaviorGO:000763510.011
regionalizationGO:00030022740.011
positive regulation of ras protein signal transductionGO:004657910.011
positive regulation of cell adhesionGO:004578510.011
neuroblast proliferationGO:000740520.011
cell substrate junction assemblyGO:000704420.011
cellular response to hypoxiaGO:007145610.011
negative regulation of macromolecule metabolic processGO:0010605760.011
regulation of protein bindingGO:004339330.011
b cell differentiationGO:003018310.011
positive regulation of map kinase activityGO:004340630.011
regulation of blood pressureGO:000821710.011
neurotransmitter transportGO:000683620.011
positive regulation of neuron apoptotic processGO:004352510.011
post embryonic morphogenesisGO:000988640.011
ovulation cycleGO:004269820.011
brain developmentGO:00074202930.011
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.011
cellular response to decreased oxygen levelsGO:003629410.011
embryo development ending in birth or egg hatchingGO:00097922710.011
negative regulation of signalingGO:0023057960.011
organism emergence from protective structureGO:007168440.011
regulation of carbohydrate metabolic processGO:000610940.011
neuromuscular synaptic transmissionGO:000727420.011
cell morphogenesis involved in differentiationGO:00009041950.011
mrna 3 end processingGO:003112420.011
determination of left right symmetryGO:00073681790.010
ameboidal type cell migrationGO:00016671430.010
negative regulation of multi organism processGO:004390130.010
embryonic skeletal joint developmentGO:007249830.010
cellular localizationGO:0051641970.010
xenobiotic metabolic processGO:000680540.010
protein polymerizationGO:005125840.010
recombinational repairGO:000072510.010
regulation of dendrite morphogenesisGO:004881430.010
dorsal ventral pattern formationGO:00099531250.010
sensory organ morphogenesisGO:00905962000.010
negative regulation of cell communicationGO:0010648960.010
female meiotic divisionGO:000714320.010
response to glucocorticoidGO:005138410.010
negative regulation of signal transductionGO:0009968940.010
mitotic g2 m transition checkpointGO:004481830.010
apoptotic processGO:00069151160.010
embryonic organ morphogenesisGO:00485622740.010
osteoclast differentiationGO:003031610.010
cytoplasm organizationGO:000702840.010
negative regulation of cellular metabolic processGO:0031324770.010
fatty acid catabolic processGO:000906210.010
odontogenesis of dentin containing toothGO:004247510.010
stem cell divisionGO:001714510.010
actin polymerization or depolymerizationGO:000815420.010
inositol lipid mediated signalingGO:004801720.010

ercc8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.039
nervous system diseaseDOID:86300.020
musculoskeletal system diseaseDOID:1700.017
disease of metabolismDOID:001466700.017
organ system cancerDOID:005068600.016
cancerDOID:16200.016
disease of cellular proliferationDOID:1456600.016
immune system diseaseDOID:291400.014
muscle tissue diseaseDOID:6600.012
muscular diseaseDOID:008000000.012
inherited metabolic disorderDOID:65500.012
myopathyDOID:42300.010