Danio rerio

34 known processes

nfe2

nuclear factor, erythroid-derived 2

nfe2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immune system processGO:00023762410.588
larval developmentGO:000216420.420
regulation of biological qualityGO:00650082630.300
cellular nitrogen compound metabolic processGO:00346412900.291
response to stressGO:00069502630.279
response to abiotic stimulusGO:00096281220.264
regulation of response to stimulusGO:00485832690.257
hematopoietic or lymphoid organ developmentGO:00485341910.254
gland developmentGO:00487321430.251
homeostatic processGO:00425921420.244
organic cyclic compound metabolic processGO:19013603010.208
regulation of metabolic processGO:00192223590.198
tube morphogenesisGO:00352393490.184
regulation of protein complex assemblyGO:004325430.165
cell surface receptor signaling pathwayGO:00071663250.158
nitrogen compound metabolic processGO:00068073190.150
regulation of multicellular organismal processGO:00512392770.139
brain developmentGO:00074202930.130
erythrocyte differentiationGO:0030218540.129
cellular component movementGO:00069283350.128
gastrulationGO:00073692080.125
positive regulation of cellular processGO:00485222010.120
regulation of multicellular organism growthGO:004001440.114
negative regulation of response to stimulusGO:00485851040.109
hemopoiesisGO:00300971830.108
regulation of cellular metabolic processGO:00313233200.107
biosynthetic processGO:00090582940.103
regulation of establishment of protein localizationGO:007020140.102
immune system developmentGO:00025201910.100
negative regulation of cellular processGO:00485232830.100
response to external stimulusGO:00096052640.096
regulation of nitrogen compound metabolic processGO:00511712510.093
cellular amine metabolic processGO:004410620.093
growthGO:00400071740.092
regulation of cytokine productionGO:000181730.092
heart developmentGO:00075073130.089
cell adhesionGO:0007155400.089
negative regulation of biological processGO:00485193040.087
positive regulation of cellular amino acid metabolic processGO:004576400.085
regulation of cellular biosynthetic processGO:00313262450.084
positive regulation of protein complex assemblyGO:003133420.083
protein importGO:001703830.082
protein import into nucleusGO:000660630.082
single organism nuclear importGO:190259330.081
protein secretionGO:000930610.080
regulation of macromolecule metabolic processGO:00602553170.078
digestive tract morphogenesisGO:00485462310.078
signal transductionGO:00071654550.076
heterocycle metabolic processGO:00464832900.075
nuclear transportGO:005116940.075
innate immune responseGO:0045087130.074
positive regulation of cellular amine metabolic processGO:003324000.074
homeostasis of number of cellsGO:0048872620.072
regulation of cellular amino acid metabolic processGO:000652100.071
liver developmentGO:0001889960.070
primitive erythrocyte differentiationGO:006031950.069
cellular nitrogen compound biosynthetic processGO:00442712180.068
regulation of anatomical structure morphogenesisGO:00226031300.068
myeloid cell homeostasisGO:0002262560.067
establishment of protein localization to organelleGO:007259440.067
head developmentGO:00603223030.064
regulation of peptidyl tyrosine phosphorylationGO:005073010.062
response to woundingGO:00096111160.062
axonogenesisGO:00074091520.062
regulation of bindingGO:005109830.062
embryonic hemopoiesisGO:0035162530.062
taxisGO:00423301090.058
positive regulation of biological processGO:00485182530.057
nucleobase containing compound biosynthetic processGO:00346542050.057
pericardium developmentGO:006003910.056
nuclear importGO:005117030.056
mitochondrion organizationGO:000700540.055
cell part morphogenesisGO:00329902460.054
regulation of protein targetingGO:190353320.052
embryonic organ developmentGO:00485683810.052
negative regulation of cytokine productionGO:000181810.052
protein targeting to nucleusGO:004474430.051
macromolecular complex subunit organizationGO:0043933740.050
axon developmentGO:00615641660.050
positive regulation of nitrogen compound metabolic processGO:0051173690.049
organonitrogen compound metabolic processGO:1901564740.049
regulation of protein import into nucleusGO:004230620.048
cellular ketone metabolic processGO:0042180110.048
hepaticobiliary system developmentGO:0061008980.048
striated muscle tissue developmentGO:00147061100.048
small molecule metabolic processGO:0044281770.047
protein metabolic processGO:00195381830.046
regulation of intracellular protein transportGO:003315730.046
myeloid cell differentiationGO:0030099860.046
maintenance of locationGO:005123540.046
response to external biotic stimulusGO:0043207970.046
vasculature developmentGO:00019442780.044
cranial nerve developmentGO:0021545420.044
branching morphogenesis of a nerveGO:004875540.043
antimicrobial humoral responseGO:001973020.043
nucleobase containing compound metabolic processGO:00061392740.043
renal system process involved in regulation of blood volumeGO:000197710.043
phagocytosisGO:000690930.042
erythrocyte homeostasisGO:0034101550.042
sensory organ developmentGO:00074233930.042
response to molecule of bacterial originGO:0002237140.041
energy homeostasisGO:009700930.041
stem cell maintenanceGO:001982740.041
regulation of signal transductionGO:00099662250.041
muscle organ developmentGO:00075171010.041
cellular biosynthetic processGO:00442492860.041
primitive hemopoiesisGO:0060215270.040
endocrine system developmentGO:0035270650.040
regulation of cellular protein metabolic processGO:0032268520.040
regulation of protein transportGO:005122330.040
negative regulation of developmental processGO:0051093650.040
organic cyclic compound biosynthetic processGO:19013622230.039
negative regulation of cell differentiationGO:0045596460.038
generation of neuronsGO:00486993850.038
protein localization to nucleusGO:003450430.038
digestive system developmentGO:00551232890.037
regulation of developmental processGO:00507932470.037
tetrapyrrole metabolic processGO:0033013100.036
protein polymerizationGO:005125840.036
organism emergence from protective structureGO:007168440.036
regulation of nucleobase containing compound metabolic processGO:00192192500.035
agingGO:000756820.035
regulation of erythrocyte differentiationGO:004564620.035
central nervous system developmentGO:00074173870.035
organic substance biosynthetic processGO:19015762890.035
cell substrate adhesionGO:003158940.035
mesoderm developmentGO:0007498880.034
negative regulation of protein phosphorylationGO:000193340.034
erythrocyte developmentGO:0048821240.034
locomotionGO:00400113130.034
epithelial tube morphogenesisGO:00605621480.033
formation of primary germ layerGO:0001704620.033
positive regulation of myeloid cell differentiationGO:004563920.033
regulation of translational initiationGO:000644610.033
amine metabolic processGO:000930820.032
regulation of protein polymerizationGO:003227120.032
regulation of nucleotide biosynthetic processGO:0030808150.032
regulation of gene expressionGO:00104682650.032
cell matrix adhesionGO:000716040.032
regulation of mitochondrion organizationGO:001082110.031
positive regulation of protein polymerizationGO:003227320.031
phosphorus metabolic processGO:00067931090.031
regulation of stem cell differentiationGO:200073640.031
regulation of protein bindingGO:004339330.031
muscle structure developmentGO:00610611960.031
neuron developmentGO:00486662620.030
neuron differentiationGO:00301823530.030
negative regulation of signal transductionGO:0009968940.030
camera type eye developmentGO:00430102220.030
nucleocytoplasmic transportGO:000691340.030
single organism localizationGO:19025782250.030
eye developmentGO:00016542770.030
regulation of primary metabolic processGO:00800903110.030
membrane organizationGO:0061024210.030
single organism membrane fusionGO:004480120.030
regulation of signalingGO:00230512350.030
rna biosynthetic processGO:00327741810.029
ammonia homeostasisGO:009727230.029
muscle tissue developmentGO:00605371100.029
regulation of response to stressGO:0080134360.029
cellular component morphogenesisGO:00329893360.029
chemotaxisGO:00069351040.029
translational initiationGO:000641330.029
positive regulation of camp biosynthetic processGO:003081920.029
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.029
regulation of inflammatory responseGO:005072720.029
cellular macromolecule metabolic processGO:00442603910.028
regulation of cell deathGO:00109411030.028
regulation of biosynthetic processGO:00098892500.028
response to ketoneGO:190165410.028
mesodermal cell differentiationGO:0048333210.028
cellular amino acid metabolic processGO:000652070.027
positive regulation of cytokine productionGO:000181920.027
regulation of protein localization to nucleusGO:190018020.027
lipid storageGO:001991510.026
regulation of purine nucleotide biosynthetic processGO:1900371150.026
olfactory lobe developmentGO:002198840.026
protein phosphorylationGO:0006468470.026
cellular macromolecule biosynthetic processGO:00346452240.026
blood coagulationGO:0007596120.026
positive regulation of cell adhesionGO:004578510.026
protein modification processGO:00362111000.026
positive regulation of transportGO:005105020.026
single organism metabolic processGO:00447102170.026
cell fate commitment involved in formation of primary germ layerGO:0060795260.026
positive regulation of cellular component biogenesisGO:004408930.026
protein complex subunit organizationGO:0071822460.026
macromolecule biosynthetic processGO:00090592270.025
peptidyl serine phosphorylationGO:001810510.025
regulation of cell communicationGO:00106462320.025
transcription dna templatedGO:00063511810.025
regulation of cell differentiationGO:00455951420.025
phosphorylationGO:0016310690.025
regulation of cellular ketone metabolic processGO:001056570.025
hatchingGO:003518840.025
digestive tract developmentGO:00485652650.025
positive regulation of response to stimulusGO:0048584800.025
cellular response to biotic stimulusGO:007121630.025
biological adhesionGO:0022610400.024
cellular response to stressGO:0033554620.024
blood vessel developmentGO:00015682460.024
organelle organizationGO:00069962270.024
cellular protein metabolic processGO:00442671290.024
ventricular cardiac muscle tissue morphogenesisGO:005501020.024
cellular amide metabolic processGO:004360340.024
defense response to fungusGO:005083220.023
defense responseGO:0006952470.023
carboxylic acid metabolic processGO:0019752220.023
blood vessel morphogenesisGO:00485142160.023
primary neural tube formationGO:001402010.023
cellular response to molecule of bacterial originGO:007121930.023
organic acid metabolic processGO:0006082310.023
cellular response to external stimulusGO:007149620.023
embryo development ending in birth or egg hatchingGO:00097922710.023
i kappab kinase nf kappab signalingGO:000724940.023
response to other organismGO:0051707970.023
multi organism processGO:00517041340.023
regulation of synaptic plasticityGO:004816710.023
developmental growth involved in morphogenesisGO:0060560860.022
oxoacid metabolic processGO:0043436310.022
peptidyl serine modificationGO:001820920.022
positive regulation of nucleobase containing compound metabolic processGO:0045935690.022
multicellular organism growthGO:003526440.022
macromolecule modificationGO:00434121110.022
organ regenerationGO:003110010.021
determination of left right symmetryGO:00073681790.021
regulation of cellular macromolecule biosynthetic processGO:20001122220.021
regulation of multicellular organismal developmentGO:20000262230.021
b cell activationGO:004211320.021
response to lipidGO:0033993600.021
response to chemicalGO:00422213200.021
positive regulation of metabolic processGO:00098931080.021
heterocycle biosynthetic processGO:00181302150.021
phagocytosis engulfmentGO:000691110.021
positive regulation of cytoskeleton organizationGO:005149530.021
regulation of phosphorus metabolic processGO:0051174430.021
transcription from rna polymerase ii promoterGO:0006366800.021
positive regulation of endothelial cell proliferationGO:000193810.021
oocyte maturationGO:000155640.021
macromolecular complex assemblyGO:0065003350.020
regulation of heart growthGO:006042020.020
heart morphogenesisGO:00030071560.020
regulation of cell activationGO:005086510.020
melanin metabolic processGO:000658220.020
positive regulation of gtp catabolic processGO:003312610.020
transportGO:00068102200.020
regulation of phosphate metabolic processGO:0019220430.020
phosphate containing compound metabolic processGO:00067961080.020
cellular protein modification processGO:00064641000.020
organonitrogen compound biosynthetic processGO:1901566470.019
skeletal muscle organ developmentGO:0060538780.019
gene expressionGO:00104672520.019
regulation of transcription from rna polymerase ii promoterGO:00063571140.019
regulation of rna biosynthetic processGO:20011412130.019
secondary metabolic processGO:001974830.019
wound healingGO:0042060900.019
response to bacteriumGO:0009617580.019
guanosine containing compound catabolic processGO:190106920.019
positive regulation of cellular metabolic processGO:0031325940.019
positive regulation of immune effector processGO:000269930.019
regulation of camp metabolic processGO:003081490.019
morphogenesis of an epitheliumGO:00020093330.019
forebrain cell migrationGO:002188510.019
kupffer s vesicle developmentGO:0070121500.019
regulation of reproductive processGO:200024140.019
myeloid cell developmentGO:0061515320.019
positive regulation of jak stat cascadeGO:004642720.018
regulation of cell motilityGO:2000145460.018
cell adhesion mediated by integrinGO:003362710.018
cellular component biogenesisGO:00440851780.018
regulation of gtpase activityGO:004308720.018
regulation of nucleocytoplasmic transportGO:004682220.018
developmental growthGO:00485891660.018
exocytosisGO:000688710.018
cell cell recognitionGO:000998810.018
mesoderm formationGO:0001707430.018
ventricular cardiac muscle tissue developmentGO:000322930.018
single organism cell adhesionGO:0098602290.018
cell deathGO:00082191210.018
intracellular signal transductionGO:0035556850.018
negative regulation of multicellular organismal processGO:0051241690.018
actin filament polymerizationGO:003004120.018
production of molecular mediator of immune responseGO:000244020.018
ameboidal type cell migrationGO:00016671430.017
axon extensionGO:0048675450.017
neuron projection morphogenesisGO:00488121610.017
angiogenesisGO:00015251580.017
multicellular organismal homeostasisGO:0048871290.017
regulation of localizationGO:00328791040.017
cell morphogenesis involved in neuron differentiationGO:00486671630.017
ribose phosphate biosynthetic processGO:0046390200.017
muscle cell differentiationGO:00426921390.017
regulation of jak stat cascadeGO:004642530.017
regulation of cell projection assemblyGO:006049140.017
purine nucleotide biosynthetic processGO:0006164200.017
regulation of i kappab kinase nf kappab signalingGO:004312240.016
positive regulation of macromolecule metabolic processGO:0010604930.016
positive regulation of secretion by cellGO:190353210.016
regulation of cellular amine metabolic processGO:003323800.016
positive regulation of secretionGO:005104710.016
regulation of filopodium assemblyGO:005148920.016
response to monosaccharideGO:003428430.016
regulation of neurogenesisGO:0050767870.016
ubiquitin dependent protein catabolic processGO:000651130.016
determination of bilateral symmetryGO:00098552040.016
cellular response to organic substanceGO:00713101050.016
cell proliferationGO:0008283800.016
organic substance transportGO:0071702580.016
coagulationGO:0050817130.016
regulation of cytoplasmic transportGO:190364940.016
cell motilityGO:00488702440.015
erythrocyte maturationGO:004324980.015
osteoclast differentiationGO:003031610.015
cellular response to lipidGO:0071396390.015
cofactor biosynthetic processGO:0051188100.015
single organism organelle organizationGO:19025891990.015
negative regulation of protein complex assemblyGO:003133310.015
gtp catabolic processGO:000618420.015
skeletal system developmentGO:00015011810.015
muscle organ morphogenesisGO:004864480.015
regulation of cell shapeGO:000836010.015
tetrapyrrole biosynthetic processGO:003301480.015
single organism transportGO:00447652060.015
purine containing compound biosynthetic processGO:0072522200.015
axonal defasciculationGO:000741420.015
cell fate specificationGO:0001708680.015
immune responseGO:0006955280.015
neuroblast proliferationGO:000740520.015
sensory organ morphogenesisGO:00905962000.015
cranial nerve morphogenesisGO:0021602150.015
g1 s transition of mitotic cell cycleGO:000008210.015
tissue remodelingGO:004877140.014
regulation of cellular component organizationGO:0051128860.014
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:007005930.014
extrinsic apoptotic signaling pathwayGO:009719130.014
erk1 and erk2 cascadeGO:007037140.014
cellular aromatic compound metabolic processGO:00067252950.014
synaptic target recognitionGO:000803910.014
response to corticosteroidGO:003196010.014
anatomical structure homeostasisGO:0060249360.014
negative regulation of metabolic processGO:0009892860.014
response to biotic stimulusGO:0009607970.014
optic nerve morphogenesisGO:002163160.014
regulation of growthGO:0040008420.014
regulation of reactive oxygen species metabolic processGO:200037720.014
response to dexamethasoneGO:007154810.014
negative regulation of protein import into nucleusGO:004230820.014
membrane invaginationGO:001032410.014
cranial nerve formationGO:0021603130.014
regulation of dna replicationGO:000627530.014
regulation of macromolecule biosynthetic processGO:00105562250.014
innervationGO:006038430.013
negative regulation of macromolecule metabolic processGO:0010605760.013
aromatic compound biosynthetic processGO:00194382170.013
cellular macromolecular complex assemblyGO:0034622240.013
regionalizationGO:00030022740.013
regulation of protein metabolic processGO:0051246560.013
protein depolymerizationGO:005126110.013
pancreas developmentGO:0031016840.013
multicellular organismal metabolic processGO:004423620.013
negative regulation of cell communicationGO:0010648960.013
neuron projection guidanceGO:0097485860.013
negative regulation of intracellular protein transportGO:009031730.013
regulation of multicellular organismal metabolic processGO:004424620.013
collagen metabolic processGO:003296320.013
actin filament based processGO:0030029640.013
regulation of cellular component movementGO:0051270550.013
cell cycle g1 s phase transitionGO:004484310.013
positive regulation of purine nucleotide biosynthetic processGO:190037380.013
regulation of cell substrate adhesionGO:001081010.013
regulation of organelle organizationGO:0033043290.013
gtp metabolic processGO:004603940.013
cytoskeleton dependent cytokinesisGO:006164030.013
negative regulation of intracellular transportGO:003238730.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
regulation of immune responseGO:0050776140.012
multicellular organismal macromolecule metabolic processGO:004425920.012
rna metabolic processGO:00160702190.012
negative regulation of immune responseGO:005077720.012
cell fate commitmentGO:0045165990.012
regulation of calcium ion dependent exocytosisGO:001715810.012
regulation of immune system processGO:0002682340.012
protein complex biogenesisGO:0070271300.012
ribonucleotide biosynthetic processGO:0009260200.012
lateral inhibitionGO:004633110.012
regulation of biomineral tissue developmentGO:007016720.012
localization of cellGO:00516742440.012
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
regulation of apoptotic processGO:0042981980.012
negative regulation of nuclear divisionGO:005178430.012
negative regulation of signalingGO:0023057960.012
regulation of purine nucleotide catabolic processGO:003312120.012
regulation of erk1 and erk2 cascadeGO:007037240.012
negative regulation of defense responseGO:003134820.011
aorta developmentGO:003590440.011
response to acid chemicalGO:0001101170.011
single organism membrane organizationGO:0044802200.011
neuromast developmentGO:0048884460.011
cellular response to lipopolysaccharideGO:007122230.011
muscle attachmentGO:001620390.011
macromolecular complex disassemblyGO:003298410.011
chordate embryonic developmentGO:00430092710.011
peptide metabolic processGO:000651810.011
negative regulation of small gtpase mediated signal transductionGO:005105810.011
otic vesicle formationGO:0030916270.011
regulation of response to external stimulusGO:0032101310.011
regulation of locomotionGO:0040012550.011
cellular component assemblyGO:00226071700.011
long chain fatty acid transportGO:001590910.011
negative regulation of dna metabolic processGO:005105340.011
ear developmentGO:00435831270.011
cell migration involved in gastrulationGO:0042074790.011
regulation of transcription dna templatedGO:00063552130.011
negative regulation of multi organism processGO:004390130.011
positive regulation of cell substrate adhesionGO:001081110.011
hormone secretionGO:004687920.011
single organism cellular localizationGO:1902580460.011
regulation of production of molecular mediator of immune responseGO:000270010.011
negative regulation of kinase activityGO:003367340.011
actin cytoskeleton organizationGO:0030036630.011
cell projection morphogenesisGO:00488582440.011
iron ion homeostasisGO:005507240.011
negative regulation of protein transportGO:005122430.010
hindbrain developmentGO:0030902910.010
membrane fusionGO:006102520.010
axon guidanceGO:0007411860.010
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.010
negative regulation of nucleobase containing compound metabolic processGO:0045934590.010
regulation of rho protein signal transductionGO:003502320.010
tube closureGO:006060610.010
epithelial cell migrationGO:0010631250.010
endocardial cushion formationGO:000327220.010
guanosine containing compound metabolic processGO:190106840.010
cell morphogenesisGO:00009022890.010
peptide transportGO:001583310.010

nfe2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.042
disease of cellular proliferationDOID:1456600.041
cancerDOID:16200.041
organ system cancerDOID:005068600.041
immune system diseaseDOID:291400.030
musculoskeletal system diseaseDOID:1700.026
cardiovascular system diseaseDOID:128700.021
muscle tissue diseaseDOID:6600.015
muscular diseaseDOID:008000000.015
hematopoietic system diseaseDOID:7400.014
disease of metabolismDOID:001466700.013
cardiomyopathyDOID:005070000.011
heart diseaseDOID:11400.011
intrinsic cardiomyopathyDOID:006003600.011
myopathyDOID:42300.011
bone marrow diseaseDOID:496100.011
aplastic anemiaDOID:1244900.011
anemiaDOID:235500.011