Danio rerio

11 known processes

med23

mediator complex subunit 23

(Aliases: zgc:91979,si:ch211-272f15.2,crsp3)

med23 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.109
agingGO:000756820.092
nitrogen compound metabolic processGO:00068073190.058
cellular nitrogen compound metabolic processGO:00346412900.048
maintenance of locationGO:005123540.047
nuclear transportGO:005116940.046
guanosine containing compound metabolic processGO:190106840.046
signal transductionGO:00071654550.046
central nervous system developmentGO:00074173870.041
positive regulation of transportGO:005105020.041
negative regulation of cellular processGO:00485232830.041
establishment of protein localization to organelleGO:007259440.041
nucleocytoplasmic transportGO:000691340.039
cellular aromatic compound metabolic processGO:00067252950.039
cellular component movementGO:00069283350.039
neuron differentiationGO:00301823530.039
heterocycle metabolic processGO:00464832900.038
generation of neuronsGO:00486993850.038
regulation of establishment of protein localizationGO:007020140.038
negative regulation of biological processGO:00485193040.038
guanosine containing compound catabolic processGO:190106920.037
cell morphogenesisGO:00009022890.037
gtp metabolic processGO:004603940.037
protein import into nucleusGO:000660630.037
cellular nitrogen compound biosynthetic processGO:00442712180.036
organic cyclic compound metabolic processGO:19013603010.036
single organism nuclear importGO:190259330.036
protein targeting to nucleusGO:004474430.035
regulation of nitrogen compound metabolic processGO:00511712510.035
gene expressionGO:00104672520.035
regulation of metabolic processGO:00192223590.035
rna metabolic processGO:00160702190.035
multicellular organism growthGO:003526440.035
morphogenesis of an epitheliumGO:00020093330.034
stem cell maintenanceGO:001982740.034
positive regulation of cellular component biogenesisGO:004408930.034
response to chemicalGO:00422213200.034
heterocycle biosynthetic processGO:00181302150.033
biosynthetic processGO:00090582940.033
lipid storageGO:001991510.033
cellular response to external stimulusGO:007149620.033
cellular amine metabolic processGO:004410620.033
amine metabolic processGO:000930820.033
nuclear importGO:005117030.033
head developmentGO:00603223030.033
protein importGO:001703830.033
aromatic compound biosynthetic processGO:00194382170.033
protein localization to nucleusGO:003450430.033
post embryonic organ developmentGO:004856940.033
regulation of biological qualityGO:00650082630.033
regulation of macromolecule metabolic processGO:00602553170.033
cell part morphogenesisGO:00329902460.032
embryonic organ developmentGO:00485683810.032
regulation of synapse assemblyGO:005196330.031
regulation of signal transductionGO:00099662250.031
nucleobase containing compound metabolic processGO:00061392740.031
regulation of cellular amine metabolic processGO:003323800.031
regulation of multicellular organismal processGO:00512392770.031
regulation of primary metabolic processGO:00800903110.031
cellular protein catabolic processGO:004425740.031
macromolecule biosynthetic processGO:00090592270.031
chordate embryonic developmentGO:00430092710.031
gtp catabolic processGO:000618420.030
organonitrogen compound metabolic processGO:1901564740.030
nucleobase containing compound biosynthetic processGO:00346542050.030
organic substance biosynthetic processGO:19015762890.030
single organism metabolic processGO:00447102170.030
regulation of protein transportGO:005122330.030
tube morphogenesisGO:00352393490.030
regulation of intracellular protein transportGO:003315730.030
positive regulation of cell cycleGO:004578730.030
brain developmentGO:00074202930.030
regionalizationGO:00030022740.030
regulation of gtp catabolic processGO:003312420.030
regulation of cellular metabolic processGO:00313233200.030
positive regulation of cellular catabolic processGO:003133130.029
positive regulation of biological processGO:00485182530.029
digestive system developmentGO:00551232890.029
cellular component morphogenesisGO:00329893360.029
cellular macromolecule metabolic processGO:00442603910.029
regulation of cytoplasmic transportGO:190364940.029
regulation of purine nucleotide catabolic processGO:003312120.028
heart developmentGO:00075073130.028
modification dependent protein catabolic processGO:001994130.028
cell projection organizationGO:00300302840.028
protein metabolic processGO:00195381830.028
regulation of gene expressionGO:00104682650.028
regulation of bindingGO:005109830.028
regulation of cellular amino acid metabolic processGO:000652100.027
regulation of cytokine productionGO:000181730.027
cell surface receptor signaling pathwayGO:00071663250.027
embryo development ending in birth or egg hatchingGO:00097922710.027
blood vessel developmentGO:00015682460.027
vasculature developmentGO:00019442780.027
positive regulation of catabolic processGO:000989640.027
regulation of multicellular organism growthGO:004001440.027
cell motilityGO:00488702440.027
regulation of protein targetingGO:190353320.026
cellular ketone metabolic processGO:0042180110.026
negative regulation of protein phosphorylationGO:000193340.026
extrinsic apoptotic signaling pathwayGO:009719130.026
cell substrate adhesionGO:003158940.026
sensory organ developmentGO:00074233930.026
regulation of cellular ketone metabolic processGO:001056570.026
regulation of protein import into nucleusGO:004230620.026
phagocytosisGO:000690930.026
regulation of nucleoside metabolic processGO:000911820.025
blood vessel morphogenesisGO:00485142160.025
regulation of synapse organizationGO:005080730.025
proteasomal protein catabolic processGO:001049820.025
organic cyclic compound biosynthetic processGO:19013622230.025
cellular biosynthetic processGO:00442492860.025
modification dependent macromolecule catabolic processGO:004363230.025
synaptic growth at neuromuscular junctionGO:005112420.025
regulation of nucleotide catabolic processGO:003081120.025
rna localizationGO:000640340.025
somatic muscle developmentGO:000752540.024
regulation of signalingGO:00230512350.024
transportGO:00068102200.024
angiogenesisGO:00015251580.024
nucleic acid metabolic processGO:00903042440.024
regulation of reproductive processGO:200024140.024
regulation of protein localization to nucleusGO:190018020.024
regulation of nucleocytoplasmic transportGO:004682220.024
response to stressGO:00069502630.024
immune system processGO:00023762410.024
adult behaviorGO:003053420.024
regulation of multicellular organismal developmentGO:20000262230.024
regulation of protein catabolic processGO:004217610.023
regulation of response to stimulusGO:00485832690.023
neuron developmentGO:00486662620.023
meiotic nuclear divisionGO:000712640.023
cellular response to nutrient levelsGO:003166920.023
positive regulation of cytoskeleton organizationGO:005149530.023
eye developmentGO:00016542770.023
regulation of biosynthetic processGO:00098892500.023
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.023
transcription dna templatedGO:00063511810.022
regulation of cell communicationGO:00106462320.022
protein acetylationGO:000647320.022
regulation of developmental processGO:00507932470.022
proteolysis involved in cellular protein catabolic processGO:005160330.022
cellular response to extracellular stimulusGO:003166820.022
establishment of localizationGO:00512342440.022
mitochondrion organizationGO:000700540.022
camera type eye developmentGO:00430102220.022
regulation of stem cell differentiationGO:200073640.022
determination of bilateral symmetryGO:00098552040.021
locomotionGO:00400113130.021
muscle structure developmentGO:00610611960.021
digestive tract developmentGO:00485652650.021
positive regulation of cellular amino acid metabolic processGO:004576400.021
cellular protein metabolic processGO:00442671290.021
cellular component disassemblyGO:002241110.021
positive regulation of cellular amine metabolic processGO:003324000.021
cell projection morphogenesisGO:00488582440.021
regulation of nucleobase containing compound metabolic processGO:00192192500.021
cell morphogenesis involved in differentiationGO:00009041950.021
cell migrationGO:00164772370.021
nucleic acid templated transcriptionGO:00976591810.021
regulation of cell shapeGO:000836010.021
cellular macromolecule biosynthetic processGO:00346452240.021
autophagyGO:000691440.021
localization of cellGO:00516742440.020
regulation of peptidyl tyrosine phosphorylationGO:005073010.020
regulation of synaptic growth at neuromuscular junctionGO:000858210.020
positive regulation of purine nucleotide catabolic processGO:003312310.020
embryonic organ morphogenesisGO:00485622740.020
single organism transportGO:00447652060.020
rna biosynthetic processGO:00327741810.020
digestive tract morphogenesisGO:00485462310.020
ameboidal type cell migrationGO:00016671430.020
adherens junction organizationGO:003433240.020
regulation of gtpase activityGO:004308720.020
cellular amino acid metabolic processGO:000652070.020
cellular response to starvationGO:000926710.020
response to drugGO:004249330.020
gastrulationGO:00073692080.020
germ line stem cell maintenanceGO:003071820.020
negative regulation of catabolic processGO:000989530.019
anterior posterior pattern specificationGO:00099521520.019
ubiquitin dependent protein catabolic processGO:000651130.019
single organism localizationGO:19025782250.019
regulation of cellular biosynthetic processGO:00313262450.019
negative regulation of kinase activityGO:003367340.019
actin polymerization or depolymerizationGO:000815420.019
cellular response to lipopolysaccharideGO:007122230.019
cell matrix adhesionGO:000716040.019
positive regulation of cellular processGO:00485222010.019
positive regulation of gtp catabolic processGO:003312610.019
regulation of protein complex assemblyGO:004325430.019
exocytosisGO:000688710.019
regulation of epithelial cell proliferationGO:005067830.019
organelle organizationGO:00069962270.019
small molecule metabolic processGO:0044281770.019
negative regulation of protein kinase activityGO:000646940.018
positive regulation of nucleoside metabolic processGO:004597910.018
immune system developmentGO:00025201910.018
atp catabolic processGO:000620040.018
compound eye developmentGO:004874920.018
stem cell proliferationGO:007208940.018
regulation of transcription dna templatedGO:00063552130.018
single organism organelle organizationGO:19025891990.018
internal protein amino acid acetylationGO:000647520.018
protein complex disassemblyGO:004324110.018
microtubule organizing center organizationGO:003102310.018
hemopoiesisGO:00300971830.018
skeletal system developmentGO:00015011810.018
cytokinesisGO:000091030.018
oxoacid metabolic processGO:0043436310.018
regulation of rna metabolic processGO:00512522240.018
negative regulation of cellular catabolic processGO:003133030.018
determination of left right symmetryGO:00073681790.018
purine ribonucleoside monophosphate catabolic processGO:000916940.017
axon developmentGO:00615641660.017
regulation of cell substrate adhesionGO:001081010.017
peptidyl lysine acetylationGO:001839420.017
regulation of macromolecule biosynthetic processGO:00105562250.017
regulation of cellular macromolecule biosynthetic processGO:20001122220.017
neuron projection developmentGO:00311751800.017
muscle cell differentiationGO:00426921390.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
centrosome organizationGO:005129710.017
organic acid metabolic processGO:0006082310.017
regulation of reactive oxygen species metabolic processGO:200037720.017
axonogenesisGO:00074091520.017
protein acylationGO:004354330.017
regulation of protein ubiquitinationGO:003139630.017
neuron projection morphogenesisGO:00488121610.017
internal peptidyl lysine acetylationGO:001839320.017
regulation of cell activationGO:005086510.017
response to uvGO:000941130.017
ribonucleoside monophosphate catabolic processGO:000915840.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
regulation of endothelial cell proliferationGO:000193610.016
regulation of neurotransmitter transportGO:005158810.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
positive regulation of cytokine productionGO:000181920.016
regulation of synaptic plasticityGO:004816710.016
neurotransmitter transportGO:000683620.016
astrocyte differentiationGO:004870810.016
meiotic cell cycle processGO:190304630.016
protein localization to plasma membraneGO:007265910.016
nucleoside monophosphate catabolic processGO:000912540.016
endosomal transportGO:001619720.016
specification of symmetryGO:00097992040.016
fertilizationGO:000956630.016
positive regulation of nucleotide catabolic processGO:003081310.016
cell deathGO:00082191210.016
cilium morphogenesisGO:0060271850.016
membrane invaginationGO:001032410.016
macromolecular complex disassemblyGO:003298410.016
negative regulation of protein serine threonine kinase activityGO:007190120.016
female sex differentiationGO:004666040.016
development of primary female sexual characteristicsGO:004654540.016
mesenchyme developmentGO:00604851270.016
positive regulation of gtpase activityGO:004354710.016
response to carbohydrateGO:000974330.016
response to external stimulusGO:00096052640.016
female gonad developmentGO:000858540.016
lipid catabolic processGO:001604240.016
cognitionGO:005089010.016
somatic stem cell maintenanceGO:003501910.015
secondary metabolic processGO:001974830.015
phagocytosis engulfmentGO:000691110.015
sensory organ morphogenesisGO:00905962000.015
zymogen activationGO:003163830.015
lateral inhibitionGO:004633110.015
retina development in camera type eyeGO:00600411460.015
protein modification processGO:00362111000.015
regulation of cell deathGO:00109411030.015
cellular component biogenesisGO:00440851780.015
deathGO:00162651210.015
programmed cell deathGO:00125011190.015
regulation of rna biosynthetic processGO:20011412130.015
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.015
phosphorus metabolic processGO:00067931090.015
single fertilizationGO:000733830.015
peptidyl serine phosphorylationGO:001810510.015
mitotic dna integrity checkpointGO:004477440.015
cellular component assemblyGO:00226071700.015
protein stabilizationGO:005082120.015
regulation of dendrite developmentGO:005077330.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
cellular response to molecule of bacterial originGO:007121930.015
hematopoietic or lymphoid organ developmentGO:00485341910.015
single organism membrane fusionGO:004480120.015
cell morphogenesis involved in neuron differentiationGO:00486671630.015
cellular response to chemical stimulusGO:00708871570.015
purine nucleoside monophosphate catabolic processGO:000912840.015
regulation of neurotransmitter secretionGO:004692810.015
intracellular signal transductionGO:0035556850.015
spermatid developmentGO:000728620.015
cellular response to biotic stimulusGO:007121630.014
stem cell differentiationGO:00488631170.014
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.014
gland developmentGO:00487321430.014
somite developmentGO:0061053960.014
peptidyl serine modificationGO:001820920.014
membrane fusionGO:006102520.014
peptidyl threonine phosphorylationGO:001810710.014
macroautophagyGO:001623610.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
system processGO:00030081850.014
myeloid cell differentiationGO:0030099860.014
regulation of protein bindingGO:004339330.014
regulation of cell differentiationGO:00455951420.014
transcription from rna polymerase ii promoterGO:0006366800.014
negative regulation of nucleocytoplasmic transportGO:004682320.014
regulation of inflammatory responseGO:005072720.014
negative regulation of mapk cascadeGO:004340940.014
positive regulation of nitrogen compound metabolic processGO:0051173690.014
muscle cell developmentGO:00550011150.014
centrosome cycleGO:000709810.014
phosphate containing compound metabolic processGO:00067961080.014
establishment of protein localization to plasma membraneGO:009000210.014
apoptotic processGO:00069151160.014
cellular response to oxygen levelsGO:007145310.014
segmentationGO:0035282970.014
response to alkaloidGO:004327920.013
positive regulation of secretionGO:005104710.013
carboxylic acid metabolic processGO:0019752220.013
protein polymerizationGO:005125840.013
regulation of apoptotic processGO:0042981980.013
regulation of sequestering of calcium ionGO:005128240.013
eye morphogenesisGO:00485921440.013
cellular protein modification processGO:00064641000.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
regulation of jak stat cascadeGO:004642530.013
positive regulation of stress activated mapk cascadeGO:003287430.013
regulation of cellular protein catabolic processGO:190336210.013
negative regulation of cytoplasmic transportGO:190365020.013
positive regulation of epithelial cell proliferationGO:005067910.013
embryonic heart tube developmentGO:00350501330.013
dorsal ventral pattern formationGO:00099531250.013
growthGO:00400071740.013
response to monosaccharideGO:003428430.013
cytoplasm organizationGO:000702840.013
macromolecule modificationGO:00434121110.013
amino acid transportGO:000686520.013
regulation of microtubule cytoskeleton organizationGO:007050730.013
response to organic substanceGO:00100331530.013
cellular carbohydrate metabolic processGO:004426240.013
response to glucoseGO:000974930.013
intracellular mrna localizationGO:000829810.013
stem cell divisionGO:001714510.013
negative regulation of intracellular transportGO:003238730.013
liver developmentGO:0001889960.013
striated muscle cell differentiationGO:00511461290.013
negative regulation of macromolecule metabolic processGO:0010605760.013
myotube differentiationGO:0014902450.013
cytosolic calcium ion transportGO:006040130.013
negative regulation of cell communicationGO:0010648960.013
b cell activationGO:004211320.013
tissue remodelingGO:004877140.013
somitogenesisGO:0001756870.013
locomotor rhythmGO:004547530.013
embryonic skeletal system developmentGO:0048706970.013
developmental growthGO:00485891660.013
actin filament based movementGO:003004810.013
determination of heart left right asymmetryGO:00613711170.012
positive regulation of metabolic processGO:00098931080.012
regulation of mrna processingGO:005068430.012
spermatid differentiationGO:004851520.012
enzyme linked receptor protein signaling pathwayGO:00071671060.012
nucleobase containing compound transportGO:001593120.012
i kappab kinase nf kappab signalingGO:000724940.012
regulation of metal ion transportGO:001095940.012
positive regulation of secretion by cellGO:190353210.012
convergent extensionGO:00600261180.012
negative regulation of epithelial cell proliferationGO:005068010.012
positive regulation of neuron deathGO:190121610.012
neurotransmitter secretionGO:000726920.012
positive regulation of epithelial cell differentiationGO:003085820.012
nuclear exportGO:005116810.012
calcium ion transport into cytosolGO:006040230.012
organelle fusionGO:004828430.012
antimicrobial humoral responseGO:001973020.012
sequestering of calcium ionGO:005120830.012
positive regulation of translationGO:004572710.012
rna transportGO:005065820.012
cell cycle g1 s phase transitionGO:004484310.012
lateral line system developmentGO:0048925760.012
synaptic transmission cholinergicGO:000727140.012
negative regulation of chromosome organizationGO:200125110.012
leukocyte proliferationGO:007066110.012
mesenchymal cell developmentGO:0014031780.012
response to hexoseGO:000974630.012
regulation of anatomical structure morphogenesisGO:00226031300.012
ovulation cycleGO:004269820.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
interspecies interaction between organismsGO:004441940.012
skeletal muscle organ developmentGO:0060538780.012
positive regulation of dna metabolic processGO:005105410.012
positive regulation of myeloid cell differentiationGO:004563920.012
regulation of blood vessel sizeGO:005088020.012
cellular response to radiationGO:007147840.012
negative regulation of protein transportGO:005122430.012
small gtpase mediated signal transductionGO:000726480.012
negative regulation of synapse assemblyGO:005196420.012
g1 s transition of mitotic cell cycleGO:000008210.012
embryonic skeletal system morphogenesisGO:0048704930.012
mesenchymal cell differentiationGO:0048762870.012
negative regulation of cytokine productionGO:000181810.012
multicellular organismal signalingGO:0035637220.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
neural crest cell differentiationGO:0014033720.012
regulation of protein complex disassemblyGO:004324410.012
sleepGO:003043110.012
sensory perception of chemical stimulusGO:000760630.012
striated muscle cell developmentGO:00550021080.012
positive regulation of protein complex assemblyGO:003133420.011
regulation of autophagyGO:001050630.011
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018440.011
epithelial cell differentiationGO:00308551160.011
regulation of meiotic cell cycleGO:005144510.011
cellular localizationGO:0051641970.011
positive regulation of neuron apoptotic processGO:004352510.011
multi organism processGO:00517041340.011
startle responseGO:000196440.011
mitotic dna damage checkpointGO:004477340.011
protein dephosphorylationGO:000647030.011
regulation of carbohydrate metabolic processGO:000610940.011
positive regulation of cell adhesionGO:004578510.011
negative regulation of metabolic processGO:0009892860.011
cartilage developmentGO:0051216960.011
cellular response to organic substanceGO:00713101050.011
epithelial tube morphogenesisGO:00605621480.011
sequestering of metal ionGO:005123830.011
protein homooligomerizationGO:005126030.011
cellular lipid catabolic processGO:004424230.011
positive regulation of jnk cascadeGO:004633030.011
lymphocyte proliferationGO:004665110.011
negative regulation of signal transductionGO:0009968940.011
mononuclear cell proliferationGO:003294310.011
axon guidanceGO:0007411860.011
positive regulation of immune effector processGO:000269930.011
erk1 and erk2 cascadeGO:007037140.011
regulation of neural precursor cell proliferationGO:200017730.011
muscle fiber developmentGO:0048747520.011
negative regulation of map kinase activityGO:004340720.011
inositol lipid mediated signalingGO:004801720.011
tube closureGO:006060610.011
primary neural tube formationGO:001402010.011
stem cell developmentGO:0048864820.011
regulation of nervous system developmentGO:0051960900.011
cilium assemblyGO:0042384580.011
response to nutrientGO:000758430.011
regulation of response to extracellular stimulusGO:003210410.011
heart morphogenesisGO:00030071560.011
negative regulation of defense responseGO:003134820.011
response to corticosteroidGO:003196010.011
cytoskeleton organizationGO:0007010960.011
action potentialGO:0001508190.011
ras protein signal transductionGO:000726570.011
muscle organ developmentGO:00075171010.011
regulation of cell developmentGO:00602841000.011
negative regulation of cellular metabolic processGO:0031324770.011
negative regulation of myeloid cell differentiationGO:004563810.011
lateral line developmentGO:0048882660.011
glial cell proliferationGO:001400940.011
negative regulation of intracellular protein transportGO:009031730.011
nucleic acid transportGO:005065720.011
maternal determination of anterior posterior axis embryoGO:000835840.011
regulation of skeletal muscle tissue developmentGO:004864140.011
peptidyl threonine modificationGO:001821010.011
golgi vesicle transportGO:004819330.011
regulation of cellular carbohydrate metabolic processGO:001067540.011
olfactory lobe developmentGO:002198840.011
carbohydrate homeostasisGO:003350010.011
regulation of extrinsic apoptotic signaling pathwayGO:200123630.011
regulation of ras gtpase activityGO:003231820.011
cellular response to reactive oxygen speciesGO:003461420.011
negative regulation of protein localization to nucleusGO:190018120.011
connective tissue developmentGO:0061448990.011
xenobiotic metabolic processGO:000680540.011
negative regulation of multi organism processGO:004390130.011
negative regulation of reproductive processGO:200024230.010
meiotic chromosome segregationGO:004513230.010
negative regulation of signalingGO:0023057960.010
cellular response to hypoxiaGO:007145610.010
regulation of response to biotic stimulusGO:000283120.010
spindle assembly involved in mitosisGO:009030710.010
sensory system developmentGO:0048880760.010

med23 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.039
musculoskeletal system diseaseDOID:1700.018
immune system diseaseDOID:291400.017
disease of metabolismDOID:001466700.016
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
organ system cancerDOID:005068600.015
eye and adnexa diseaseDOID:149200.015
nervous system diseaseDOID:86300.015
sensory system diseaseDOID:005015500.015
eye diseaseDOID:561400.012
cardiovascular system diseaseDOID:128700.012