Danio rerio

0 known processes

ttr

transthyretin (prealbumin, amyloidosis type I)

(Aliases: zgc:103583)

ttr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.055
positive regulation of transportGO:005105020.049
agingGO:000756820.042
maintenance of locationGO:005123540.041
multicellular organism growthGO:003526440.039
regulation of multicellular organism growthGO:004001440.038
lipid storageGO:001991510.036
regulation of cytokine productionGO:000181730.035
signal transductionGO:00071654550.032
phagocytosisGO:000690930.031
adult behaviorGO:003053420.030
regulation of cellular amine metabolic processGO:003323800.030
oxoacid metabolic processGO:0043436310.029
cellular amine metabolic processGO:004410620.029
cellular ketone metabolic processGO:0042180110.028
establishment of protein localization to organelleGO:007259440.028
response to chemicalGO:00422213200.028
dicarboxylic acid transportGO:000683510.028
amine metabolic processGO:000930820.027
regulation of biological qualityGO:00650082630.026
heterocycle metabolic processGO:00464832900.026
cellular macromolecule metabolic processGO:00442603910.026
regulation of metabolic processGO:00192223590.025
response to drugGO:004249330.025
cellular nitrogen compound metabolic processGO:00346412900.025
single organism metabolic processGO:00447102170.025
regulation of cellular amino acid metabolic processGO:000652100.024
nitrogen compound metabolic processGO:00068073190.024
regulation of blood pressureGO:000821710.024
embryonic organ developmentGO:00485683810.024
stem cell proliferationGO:007208940.024
regulation of tube sizeGO:003515020.024
mitochondrion organizationGO:000700540.023
organic substance biosynthetic processGO:19015762890.023
small molecule metabolic processGO:0044281770.023
positive regulation of cellular component biogenesisGO:004408930.023
regulation of circadian rhythmGO:004275240.022
hormone transportGO:000991420.022
response to stressGO:00069502630.022
organic acid metabolic processGO:0006082310.022
protein localization to nucleusGO:003450430.022
nuclear transportGO:005116940.022
regulation of blood vessel sizeGO:005088020.022
aromatic compound biosynthetic processGO:00194382170.022
internal peptidyl lysine acetylationGO:001839320.022
regulation of signalingGO:00230512350.022
organic cyclic compound metabolic processGO:19013603010.022
positive regulation of cell cycleGO:004578730.021
autophagyGO:000691440.021
response to carbohydrateGO:000974330.021
cellular aromatic compound metabolic processGO:00067252950.021
biosynthetic processGO:00090582940.021
nucleobase containing compound metabolic processGO:00061392740.021
hormone secretionGO:004687920.021
regulation of establishment of protein localizationGO:007020140.021
regulation of cellular ketone metabolic processGO:001056570.021
stem cell maintenanceGO:001982740.021
protein targeting to nucleusGO:004474430.020
synaptic vesicle transportGO:004848910.020
protein localization to plasma membraneGO:007265910.020
protein acetylationGO:000647320.020
cellular response to external stimulusGO:007149620.020
protein import into nucleusGO:000660630.020
protein importGO:001703830.020
heterocycle biosynthetic processGO:00181302150.020
cellular response to nutrient levelsGO:003166920.020
cognitionGO:005089010.020
peptidyl lysine acetylationGO:001839420.020
regulation of protein transportGO:005122330.020
gene expressionGO:00104672520.020
regulation of cytoplasmic transportGO:190364940.020
central nervous system developmentGO:00074173870.020
positive regulation of catabolic processGO:000989640.020
positive regulation of secretionGO:005104710.020
positive regulation of cytokine productionGO:000181920.020
response to nutrientGO:000758430.020
single organism nuclear importGO:190259330.020
nuclear importGO:005117030.020
cellular response to extracellular stimulusGO:003166820.019
positive regulation of secretion by cellGO:190353210.019
cellular component movementGO:00069283350.019
nucleocytoplasmic transportGO:000691340.019
positive regulation of cellular catabolic processGO:003133130.019
carboxylic acid metabolic processGO:0019752220.019
regulation of macromolecule metabolic processGO:00602553170.019
regulation of protein targetingGO:190353320.019
regulation of protein complex assemblyGO:004325430.019
synaptic growth at neuromuscular junctionGO:005112420.019
response to hexoseGO:000974630.019
rna metabolic processGO:00160702190.019
regulation of cell activationGO:005086510.019
locomotionGO:00400113130.019
response to monosaccharideGO:003428430.019
transportGO:00068102200.019
system processGO:00030081850.019
nucleic acid metabolic processGO:00903042440.019
regulation of nucleocytoplasmic transportGO:004682220.019
cellular protein catabolic processGO:004425740.019
cellular component morphogenesisGO:00329893360.019
sensory perception of chemical stimulusGO:000760630.019
peptide transportGO:001583310.018
amino acid transportGO:000686520.018
regulation of nitrogen compound metabolic processGO:00511712510.018
neurotransmitter transportGO:000683620.018
tissue remodelingGO:004877140.018
response to hydrogen peroxideGO:004254230.018
regulation of mrna processingGO:005068430.018
regulation of gene expressionGO:00104682650.018
ubiquitin dependent protein catabolic processGO:000651130.018
sensory organ developmentGO:00074233930.018
establishment of synaptic vesicle localizationGO:009748010.018
positive regulation of cellular amino acid metabolic processGO:004576400.018
secondary metabolic processGO:001974830.018
positive regulation of immune effector processGO:000269930.018
internal protein amino acid acetylationGO:000647520.018
cellular carbohydrate metabolic processGO:004426240.018
regulation of peptidyl tyrosine phosphorylationGO:005073010.018
synaptic vesicle localizationGO:009747910.018
neuron differentiationGO:00301823530.018
regulation of synaptic plasticityGO:004816710.018
regulation of cellular metabolic processGO:00313233200.018
macromolecule biosynthetic processGO:00090592270.017
protein acylationGO:004354330.017
regulation of cell communicationGO:00106462320.017
cellular response to lipopolysaccharideGO:007122230.017
regulation of multicellular organismal processGO:00512392770.017
somatic muscle developmentGO:000752540.017
phagocytosis engulfmentGO:000691110.017
cell projection organizationGO:00300302840.017
modification dependent macromolecule catabolic processGO:004363230.017
organonitrogen compound metabolic processGO:1901564740.017
response to external stimulusGO:00096052640.017
regulation of intracellular protein transportGO:003315730.017
immune system processGO:00023762410.017
meiotic nuclear divisionGO:000712640.017
response to amino acidGO:004320020.017
glucose homeostasisGO:004259310.017
regulation of metal ion transportGO:001095940.017
regulation of dendrite developmentGO:005077330.017
positive regulation of cellular amine metabolic processGO:003324000.017
vasculature developmentGO:00019442780.017
cellular response to starvationGO:000926710.017
liver developmentGO:0001889960.017
regulation of reproductive processGO:200024140.017
exocytosisGO:000688710.017
single organism transportGO:00447652060.017
compound eye developmentGO:004874920.017
response to glucoseGO:000974930.016
regulation of inflammatory responseGO:005072720.016
guanosine containing compound metabolic processGO:190106840.016
single organism localizationGO:19025782250.016
organic cyclic compound biosynthetic processGO:19013622230.016
regulation of transporter activityGO:003240920.016
determination of bilateral symmetryGO:00098552040.016
nucleobase containing compound biosynthetic processGO:00346542050.016
meiotic cell cycle processGO:190304630.016
smooth muscle contractionGO:000693920.016
guanosine containing compound catabolic processGO:190106920.016
symbiosis encompassing mutualism through parasitismGO:004440340.016
regulation of response to stimulusGO:00485832690.016
regulation of macromolecule biosynthetic processGO:00105562250.016
gtp metabolic processGO:004603940.016
regulation of primary metabolic processGO:00800903110.016
establishment of localizationGO:00512342440.016
b cell activationGO:004211320.016
eye developmentGO:00016542770.016
hepaticobiliary system developmentGO:0061008980.016
protein metabolic processGO:00195381830.016
regulation of protein import into nucleusGO:004230620.016
proteolysis involved in cellular protein catabolic processGO:005160330.016
morphogenesis of an epitheliumGO:00020093330.016
regulation of sodium ion transportGO:000202820.016
lipid catabolic processGO:001604240.016
proteasomal protein catabolic processGO:001049820.016
positive regulation of biological processGO:00485182530.016
rna localizationGO:000640340.016
regulation of signal transductionGO:00099662250.016
cytokinesisGO:000091030.016
regulation of bindingGO:005109830.015
cellular response to chemical stimulusGO:00708871570.015
cortical cytoskeleton organizationGO:003086510.015
regulation of cellular biosynthetic processGO:00313262450.015
gtp catabolic processGO:000618420.015
regulation of synapse organizationGO:005080730.015
golgi vesicle transportGO:004819330.015
membrane invaginationGO:001032410.015
circulatory system processGO:0003013870.015
regulation of phGO:000688530.015
response to topologically incorrect proteinGO:003596620.015
regulation of stem cell proliferationGO:007209120.015
modification dependent protein catabolic processGO:001994130.015
neuron developmentGO:00486662620.015
chemosensory behaviorGO:000763510.015
neuroblast proliferationGO:000740520.015
cellular amino acid metabolic processGO:000652070.015
positive regulation of protein complex assemblyGO:003133420.015
regulation of synapse assemblyGO:005196330.015
regulation of nucleobase containing compound metabolic processGO:00192192500.015
i kappab kinase nf kappab signalingGO:000724940.015
positive regulation of cytoskeleton organizationGO:005149530.015
immune system developmentGO:00025201910.015
sensory organ morphogenesisGO:00905962000.015
carbohydrate homeostasisGO:003350010.015
sequestering of metal ionGO:005123830.015
regulation of developmental processGO:00507932470.015
negative regulation of protein kinase activityGO:000646940.015
neurotransmitter secretionGO:000726920.015
embryonic organ morphogenesisGO:00485622740.015
regulation of rna metabolic processGO:00512522240.015
cellular response to molecule of bacterial originGO:007121930.015
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.015
negative regulation of protein phosphorylationGO:000193340.014
inositol lipid mediated signalingGO:004801720.014
cellular nitrogen compound biosynthetic processGO:00442712180.014
endosomal transportGO:001619720.014
neuron neuron synaptic transmissionGO:000727010.014
cellular component biogenesisGO:00440851780.014
skeletal system developmentGO:00015011810.014
endocrine processGO:005088620.014
cellular lipid catabolic processGO:004424230.014
atp catabolic processGO:000620040.014
cellular macromolecule biosynthetic processGO:00346452240.014
membrane fusionGO:006102520.014
positive regulation of cytosolic calcium ion concentrationGO:000720440.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
ribonucleoside monophosphate catabolic processGO:000915840.014
regulation of autophagyGO:001050630.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
response to vitaminGO:003327330.014
regulation of systemic arterial blood pressureGO:000307310.014
positive regulation of cell activationGO:005086710.014
organism emergence from protective structureGO:007168440.014
purine nucleoside monophosphate catabolic processGO:000912840.014
rna biosynthetic processGO:00327741810.014
cell substrate adhesionGO:003158940.014
regulation of carbohydrate metabolic processGO:000610940.014
sequestering of calcium ionGO:005120830.014
nucleoside monophosphate catabolic processGO:000912540.014
mononuclear cell proliferationGO:003294310.014
tube morphogenesisGO:00352393490.014
regulation of transmembrane transporter activityGO:002289820.014
organelle organizationGO:00069962270.014
generation of neuronsGO:00486993850.014
cellular biosynthetic processGO:00442492860.014
cellular amide metabolic processGO:004360340.014
negative regulation of sequestering of calcium ionGO:005128340.014
regulation of epithelial cell proliferationGO:005067830.014
response to uvGO:000941130.014
spermatid developmentGO:000728620.014
protein dephosphorylationGO:000647030.014
regulation of meiotic cell cycleGO:005144510.014
synaptic transmission cholinergicGO:000727140.014
leukocyte proliferationGO:007066110.014
cell surface receptor signaling pathwayGO:00071663250.014
response to alkaloidGO:004327920.014
negative regulation of catabolic processGO:000989530.014
regulation of endocrine processGO:004406020.014
response to organic substanceGO:00100331530.014
regulation of alternative mrna splicing via spliceosomeGO:000038110.014
post embryonic organ developmentGO:004856940.014
hatchingGO:003518840.013
regulation of biosynthetic processGO:00098892500.013
regulation of protein modification by small protein conjugation or removalGO:190332030.013
blood circulationGO:0008015870.013
positive regulation of lymphocyte mediated immunityGO:000270810.013
regulation of protein catabolic processGO:004217610.013
negative regulation of kinase activityGO:003367340.013
establishment of protein localization to plasma membraneGO:009000210.013
regulation of cell shapeGO:000836010.013
ion transportGO:00068111140.013
regulation of hormone secretionGO:004688320.013
regulation of neurotransmitter transportGO:005158810.013
cytoskeleton dependent cytokinesisGO:006164030.013
endocrine hormone secretionGO:006098620.013
regulation of ion transmembrane transporter activityGO:003241220.013
regulation of dendrite morphogenesisGO:004881430.013
negative regulation of biological processGO:00485193040.013
camera type eye developmentGO:00430102220.013
heart developmentGO:00075073130.013
positive regulation of blood circulationGO:190352420.013
mechanosensory behaviorGO:000763820.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
production of molecular mediator of immune responseGO:000244020.013
digestive tract developmentGO:00485652650.013
vacuolar transportGO:000703420.013
regulation of rna biosynthetic processGO:20011412130.013
digestive system developmentGO:00551232890.013
locomotor rhythmGO:004547530.013
carbohydrate biosynthetic processGO:001605110.013
interspecies interaction between organismsGO:004441940.013
regulation of stem cell differentiationGO:200073640.013
specification of symmetryGO:00097992040.013
entrainment of circadian clockGO:000964920.013
actin filament based movementGO:003004810.013
alcohol biosynthetic processGO:004616520.013
intracellular mrna localizationGO:000829810.013
negative regulation of cytoplasmic transportGO:190365020.013
regulation of reactive oxygen species metabolic processGO:200037720.013
transmembrane transportGO:00550851200.013
regulation of protein localization to nucleusGO:190018020.013
cell part morphogenesisGO:00329902460.013
single organism organelle organizationGO:19025891990.013
protein polymerizationGO:005125840.013
lymphocyte proliferationGO:004665110.013
protein stabilizationGO:005082120.013
positive regulation of dna metabolic processGO:005105410.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.013
transcription from rna polymerase ii promoterGO:0006366800.013
protein homooligomerizationGO:005126030.013
growthGO:00400071740.013
actin polymerization or depolymerizationGO:000815420.013
sleepGO:003043110.013
single organism membrane fusionGO:004480120.013
cellular component disassemblyGO:002241110.013
homeostatic processGO:00425921420.013
regulation of neurotransmitter secretionGO:004692810.013
cellular response to organic substanceGO:00713101050.013
developmental growthGO:00485891660.013
cytoplasm organizationGO:000702840.012
regulation of production of molecular mediator of immune responseGO:000270010.012
positive regulation of protein polymerizationGO:003227320.012
cell morphogenesisGO:00009022890.012
small molecule catabolic processGO:004428230.012
cellular response to biotic stimulusGO:007121630.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
cell projection morphogenesisGO:00488582440.012
ion transmembrane transportGO:0034220910.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
positive regulation of leukocyte mediated immunityGO:000270510.012
cell migrationGO:00164772370.012
regulation of nucleic acid templated transcriptionGO:19035062130.012
spermatid differentiationGO:004851520.012
protein secretionGO:000930610.012
regulation of sequestering of calcium ionGO:005128240.012
macromolecular complex disassemblyGO:003298410.012
lateral inhibitionGO:004633110.012
negative regulation of protein transportGO:005122430.012
calcium ion transport into cytosolGO:006040230.012
negative regulation of mapk cascadeGO:004340940.012
gastrulationGO:00073692080.012
positive regulation of map kinase activityGO:004340630.012
localization of cellGO:00516742440.012
regulation of protein ubiquitinationGO:003139630.012
response to unfolded proteinGO:000698620.012
extrinsic apoptotic signaling pathwayGO:009719130.012
regulation of purine nucleotide catabolic processGO:003312120.012
regulation of mrna splicing via spliceosomeGO:004802430.012
long chain fatty acid metabolic processGO:000167610.012
cell matrix adhesionGO:000716040.012
cell motilityGO:00488702440.012
negative regulation of nucleocytoplasmic transportGO:004682320.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
regulation of dna replicationGO:000627530.012
female gonad developmentGO:000858540.012
response to amphetamineGO:000197510.012
leukocyte mediated cytotoxicityGO:000190910.012
protein complex disassemblyGO:004324110.012
cellular component assemblyGO:00226071700.012
heart morphogenesisGO:00030071560.012
regulation of nucleoside metabolic processGO:000911820.012
multi organism processGO:00517041340.012
regulation of neuronal synaptic plasticityGO:004816810.012
gland developmentGO:00487321430.011
organelle fusionGO:004828430.011
regulation of response to extracellular stimulusGO:003210410.011
negative regulation of cellular catabolic processGO:003133030.011
cellular response to reactive oxygen speciesGO:003461420.011
protein heterooligomerizationGO:005129110.011
regulation of transcription dna templatedGO:00063552130.011
superoxide metabolic processGO:000680120.011
nucleic acid templated transcriptionGO:00976591810.011
cartilage developmentGO:0051216960.011
phosphatidylinositol mediated signalingGO:004801520.011
cellular protein metabolic processGO:00442671290.011
development of primary female sexual characteristicsGO:004654540.011
digestive tract morphogenesisGO:00485462310.011
response to amineGO:001407510.011
regulation of protein polymerizationGO:003227120.011
cytosolic calcium ion transportGO:006040130.011
regulation of membrane potentialGO:0042391230.011
single fertilizationGO:000733830.011
blood vessel developmentGO:00015682460.011
cellular monovalent inorganic cation homeostasisGO:003000420.011
regulation of lipid transportGO:003236840.011
release of sequestered calcium ion into cytosolGO:005120930.011
retina development in camera type eyeGO:00600411460.011
regulation of nucleotide catabolic processGO:003081120.011
negative regulation of cellular processGO:00485232830.011
phosphatidylinositol 3 kinase signalingGO:001406520.011
negative regulation of intracellular transportGO:003238730.011
positive regulation of leukocyte differentiationGO:190210710.011
regulation of cellular carbohydrate metabolic processGO:001067540.011
inorganic ion transmembrane transportGO:0098660570.011
determination of left right symmetryGO:00073681790.011
multicellular organismal response to stressGO:003355520.011
neuromuscular synaptic transmissionGO:000727420.011
female sex differentiationGO:004666040.011
transcription dna templatedGO:00063511810.011
hemopoiesisGO:00300971830.011
regulation of jak stat cascadeGO:004642530.011
regulation of myotube differentiationGO:001083020.011
carboxylic acid catabolic processGO:004639530.011
regulation of leukocyte mediated immunityGO:000270310.011
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.011
angiogenesisGO:00015251580.011
actin filament polymerizationGO:003004120.011
germ line stem cell maintenanceGO:003071820.011
negative regulation of dna metabolic processGO:005105340.011
positive regulation of notch signaling pathwayGO:004574730.011
energy reserve metabolic processGO:000611220.011
lipid homeostasisGO:005508830.011
organic acid catabolic processGO:001605430.011
regionalizationGO:00030022740.011
positive regulation of cell adhesionGO:004578510.011
positive regulation of jnk cascadeGO:004633030.011
regulation of i kappab kinase nf kappab signalingGO:004312240.011
catechol containing compound metabolic processGO:000971220.011
regulation of gtpase activityGO:004308720.011
regulation of response to nutrient levelsGO:003210710.011
cellular response to oxygen levelsGO:007145310.010
negative regulation of secretionGO:005104820.010
adherens junction organizationGO:003433240.010
antimicrobial humoral responseGO:001973020.010
maternal determination of anterior posterior axis embryoGO:000835840.010
cortical actin cytoskeleton organizationGO:003086610.010
calcium mediated signalingGO:001972220.010
tube closureGO:006060610.010
fatty acid transportGO:001590810.010
cell morphogenesis involved in differentiationGO:00009041950.010
inorganic cation transmembrane transportGO:0098662500.010
negative regulation of defense responseGO:003134820.010
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.010
centrosome organizationGO:005129710.010
intracellular signal transductionGO:0035556850.010
neuron projection developmentGO:00311751800.010
cell killingGO:000190620.010
neuron projection morphogenesisGO:00488121610.010
startle responseGO:000196440.010
erk1 and erk2 cascadeGO:007037140.010
cell cycle g1 s phase transitionGO:004484310.010

ttr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.029
disease of metabolismDOID:001466700.020
nervous system diseaseDOID:86300.018
inherited metabolic disorderDOID:65500.015
cancerDOID:16200.014
disease of cellular proliferationDOID:1456600.014
organ system cancerDOID:005068600.013
cardiovascular system diseaseDOID:128700.011
musculoskeletal system diseaseDOID:1700.011