Danio rerio

40 known processes

blm

Bloom syndrome

blm biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitotic recombinationGO:000631220.461
response to arsenic containing substanceGO:004668550.426
negative regulation of dna recombinationGO:004591020.328
regulation of dna recombinationGO:000001820.253
monoamine transportGO:001584410.195
sensory organ developmentGO:00074233930.159
eye developmentGO:00016542770.127
agingGO:000756820.115
synaptic transmission glycinergicGO:006001210.100
nucleic acid metabolic processGO:00903042440.098
transmembrane transportGO:00550851200.097
neuron neuron synaptic transmissionGO:000727010.092
amino acid transportGO:000686520.089
regulation of biological qualityGO:00650082630.080
cellular macromolecule metabolic processGO:00442603910.077
response to chemicalGO:00422213200.061
regulation of bindingGO:005109830.059
negative regulation of dna metabolic processGO:005105340.059
hematopoietic or lymphoid organ developmentGO:00485341910.056
regulation of macromolecule metabolic processGO:00602553170.056
negative regulation of cellular processGO:00485232830.055
modification dependent protein catabolic processGO:001994130.054
regulation of multicellular organismal processGO:00512392770.053
regulation of cytokine productionGO:000181730.052
multicellular organism growthGO:003526440.051
neutral amino acid transportGO:001580420.046
protein acetylationGO:000647320.046
cellular component morphogenesisGO:00329893360.045
regulation of protein bindingGO:004339330.044
negative regulation of biological processGO:00485193040.044
single organism localizationGO:19025782250.044
nitrogen compound metabolic processGO:00068073190.043
response to drugGO:004249330.042
digestive system developmentGO:00551232890.042
positive regulation of cell cycleGO:004578730.040
nucleocytoplasmic transportGO:000691340.039
erythrocyte homeostasisGO:0034101550.039
regulation of nitrogen compound metabolic processGO:00511712510.039
protein localization to nucleusGO:003450430.039
proteolysis involved in cellular protein catabolic processGO:005160330.036
system processGO:00030081850.035
cellular component movementGO:00069283350.035
g1 s transition of mitotic cell cycleGO:000008210.035
regulation of cellular metabolic processGO:00313233200.035
regulation of cellular amine metabolic processGO:003323800.035
amine metabolic processGO:000930820.034
regulation of primary metabolic processGO:00800903110.033
nuclear transportGO:005116940.033
ubiquitin dependent protein catabolic processGO:000651130.033
organic hydroxy compound transportGO:0015850140.033
single organism transportGO:00447652060.032
cellular aromatic compound metabolic processGO:00067252950.032
adult behaviorGO:003053420.032
regulation of nucleoside metabolic processGO:000911820.031
positive regulation of cytosolic calcium ion concentrationGO:000720440.031
membrane hyperpolarizationGO:006008110.031
regionalizationGO:00030022740.031
embryonic organ developmentGO:00485683810.031
cell projection assemblyGO:0030031640.031
somatic muscle developmentGO:000752540.030
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.030
regulation of signalingGO:00230512350.030
organic cyclic compound metabolic processGO:19013603010.030
muscle hypertrophyGO:001489620.030
left right pattern formationGO:0060972190.030
cell cycle g1 s phase transitionGO:004484310.030
ion transmembrane transportGO:0034220910.029
establishment of protein localization to organelleGO:007259440.029
localization of cellGO:00516742440.028
camera type eye developmentGO:00430102220.028
regulation of muscle hypertrophyGO:001474320.028
pore complex assemblyGO:004693120.028
positive regulation of cellular amino acid metabolic processGO:004576400.028
anion transmembrane transportGO:0098656120.027
regulation of synaptic plasticityGO:004816710.027
regulation of protein transportGO:005122330.027
regulation of peptidyl tyrosine phosphorylationGO:005073010.027
heterocycle metabolic processGO:00464832900.027
regulation of dna metabolic processGO:0051052110.026
regulation of membrane potentialGO:0042391230.026
leukocyte proliferationGO:007066110.026
positive regulation of small gtpase mediated signal transductionGO:005105710.026
proteasomal protein catabolic processGO:001049820.025
microtubule organizing center organizationGO:003102310.025
protein secretionGO:000930610.025
neurotransmitter secretionGO:000726920.025
developmental programmed cell deathGO:001062340.025
response to carbohydrateGO:000974330.025
regulation of nucleotide catabolic processGO:003081120.025
extrinsic apoptotic signaling pathwayGO:009719130.025
homeostasis of number of cellsGO:0048872620.025
regulation of cellular amino acid metabolic processGO:000652100.025
establishment of localizationGO:00512342440.025
cellular amine metabolic processGO:004410620.024
modification dependent macromolecule catabolic processGO:004363230.024
response to stressGO:00069502630.024
negative regulation of cellular catabolic processGO:003133030.024
nuclear importGO:005117030.024
sensory organ morphogenesisGO:00905962000.023
nucleobase containing compound metabolic processGO:00061392740.023
transportGO:00068102200.023
cellular response to oxygen levelsGO:007145310.022
cellular protein catabolic processGO:004425740.022
oxoacid metabolic processGO:0043436310.022
regulation of neurotransmitter secretionGO:004692810.022
neurotransmitter transportGO:000683620.022
positive regulation of map kinase activityGO:004340630.022
cellular ketone metabolic processGO:0042180110.022
nitrogen compound transportGO:0071705230.022
maintenance of locationGO:005123540.022
developmental growthGO:00485891660.022
liver developmentGO:0001889960.022
peptide transportGO:001583310.022
nuclear exportGO:005116810.021
cell motilityGO:00488702440.021
immune system processGO:00023762410.021
protein acylationGO:004354330.021
regulation of nucleobase containing compound metabolic processGO:00192192500.021
cell morphogenesisGO:00009022890.021
protein targeting to nucleusGO:004474430.021
cellular protein complex assemblyGO:0043623190.021
centrosome organizationGO:005129710.021
regulation of gtp catabolic processGO:003312420.021
regulation of stem cell differentiationGO:200073640.021
i kappab kinase nf kappab signalingGO:000724940.020
response to heatGO:000940860.020
regulation of protein localization to nucleusGO:190018020.020
primitive erythrocyte differentiationGO:006031950.020
ion transportGO:00068111140.020
peptidyl serine phosphorylationGO:001810510.020
negative regulation of protein kinase activityGO:000646940.020
digestive tract developmentGO:00485652650.019
response to amino acidGO:004320020.019
regulation of transporter activityGO:003240920.019
regulation of rho protein signal transductionGO:003502320.019
regulation of cytoplasmic transportGO:190364940.019
positive regulation of myeloid cell differentiationGO:004563920.019
positive regulation of catabolic processGO:000989640.019
regulation of cellular ketone metabolic processGO:001056570.019
guanosine containing compound catabolic processGO:190106920.019
immune system developmentGO:00025201910.019
protein polymerizationGO:005125840.019
centrosome cycleGO:000709810.019
protein metabolic processGO:00195381830.019
guanosine containing compound metabolic processGO:190106840.019
regulation of multicellular organism growthGO:004001440.019
positive regulation of transportGO:005105020.019
actin polymerization or depolymerizationGO:000815420.018
negative regulation of hormone secretionGO:004688820.018
locomotor rhythmGO:004547530.018
positive regulation of cellular catabolic processGO:003133130.018
positive regulation of ras protein signal transductionGO:004657910.018
regulation of purine nucleotide catabolic processGO:003312120.018
gtp metabolic processGO:004603940.018
regulation of protein complex assemblyGO:004325430.018
muscle system processGO:0003012200.018
lipid storageGO:001991510.018
homeostatic processGO:00425921420.018
regulation of cell differentiationGO:00455951420.018
gland developmentGO:00487321430.018
regulation of protein catabolic processGO:004217610.017
negative regulation of catabolic processGO:000989530.017
gtp catabolic processGO:000618420.017
response to hexoseGO:000974630.017
meiotic nuclear divisionGO:000712640.017
organic acid metabolic processGO:0006082310.017
negative regulation of kinase activityGO:003367340.017
cellular component disassemblyGO:002241110.017
positive regulation of cellular amine metabolic processGO:003324000.017
stem cell maintenanceGO:001982740.017
erythrocyte differentiationGO:0030218540.017
myeloid cell differentiationGO:0030099860.017
carboxylic acid metabolic processGO:0019752220.017
cellular amino acid metabolic processGO:000652070.017
myeloid cell homeostasisGO:0002262560.017
regulation of intracellular protein transportGO:003315730.017
regulation of cell shapeGO:000836010.017
hemopoiesisGO:00300971830.017
protein import into nucleusGO:000660630.017
cellular biosynthetic processGO:00442492860.017
locomotionGO:00400113130.017
cellular transition metal ion homeostasisGO:004691630.017
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.017
meiotic chromosome segregationGO:004513230.017
organelle localizationGO:0051640490.017
gene expressionGO:00104672520.016
positive regulation of cell deathGO:0010942290.016
response to temperature stimulusGO:0009266150.016
neuron remodelingGO:001632210.016
regulation of endocrine processGO:004406020.016
regulation of gtpase activityGO:004308720.016
hormone secretionGO:004687920.016
regulation of blood pressureGO:000821710.016
response to abiotic stimulusGO:00096281220.016
regulation of cell communicationGO:00106462320.016
regulation of nucleocytoplasmic transportGO:004682220.016
autophagyGO:000691440.016
regulation of neurotransmitter transportGO:005158810.016
growthGO:00400071740.016
regulation of cellular macromolecule biosynthetic processGO:20001122220.016
determination of left right symmetryGO:00073681790.016
positive regulation of secretionGO:005104710.016
response to hydrogen peroxideGO:004254230.015
action potentialGO:0001508190.015
small molecule metabolic processGO:0044281770.015
negative regulation of cellular metabolic processGO:0031324770.015
signal transduction in absence of ligandGO:003803410.015
cell substrate adhesionGO:003158940.015
eye morphogenesisGO:00485921440.015
embryonic hemopoiesisGO:0035162530.015
cellular response to external stimulusGO:007149620.015
fertilizationGO:000956630.015
rna localizationGO:000640340.015
response to glucoseGO:000974930.015
regulation of autophagyGO:001050630.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
cell migrationGO:00164772370.015
regulation of dendrite developmentGO:005077330.015
l amino acid transportGO:001580710.015
blood vessel developmentGO:00015682460.014
atp catabolic processGO:000620040.014
regulation of multicellular organismal developmentGO:20000262230.014
regulation of hormone secretionGO:004688320.014
hepaticobiliary system developmentGO:0061008980.014
cell part morphogenesisGO:00329902460.014
cardiac atrium developmentGO:000323040.014
organonitrogen compound metabolic processGO:1901564740.014
larval developmentGO:000216420.014
cellular response to extracellular stimulusGO:003166820.014
generation of neuronsGO:00486993850.014
regulation of mrna splicing via spliceosomeGO:004802430.014
organic substance biosynthetic processGO:19015762890.014
eye photoreceptor cell differentiationGO:0001754450.014
regulation of anatomical structure sizeGO:0090066330.014
cellular response to nutrient levelsGO:003166920.014
positive regulation of cell adhesionGO:004578510.014
single organism organelle organizationGO:19025891990.014
positive regulation of protein complex assemblyGO:003133420.014
negative regulation of metabolic processGO:0009892860.014
muscle structure developmentGO:00610611960.014
positive regulation of nucleoside metabolic processGO:004597910.014
production of molecular mediator of immune responseGO:000244020.013
single fertilizationGO:000733830.013
carbohydrate homeostasisGO:003350010.013
morphogenesis of an epitheliumGO:00020093330.013
b cell activationGO:004211320.013
transcription dna templatedGO:00063511810.013
cell projection organizationGO:00300302840.013
cytoskeleton dependent cytokinesisGO:006164030.013
negative regulation of protein phosphorylationGO:000193340.013
peptidyl serine modificationGO:001820920.013
cellular component assemblyGO:00226071700.013
phagocytosisGO:000690930.013
positive regulation of biological processGO:00485182530.013
mitochondrion organizationGO:000700540.013
single organism nuclear importGO:190259330.013
regulation of reactive oxygen species metabolic processGO:200037720.013
regulation of synaptic transmission glycinergicGO:006009210.013
regulation of extrinsic apoptotic signaling pathwayGO:200123630.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
head developmentGO:00603223030.013
response to nutrientGO:000758430.013
retina development in camera type eyeGO:00600411460.013
endocrine processGO:005088620.013
meiotic cell cycle processGO:190304630.013
dopamine metabolic processGO:004241720.013
regulation of reproductive processGO:200024140.013
cell cycle arrestGO:000705010.013
b cell mediated immunityGO:001972430.013
protein complex disassemblyGO:004324110.013
regulation of signal transductionGO:00099662250.013
reflexGO:006000420.013
cell surface receptor signaling pathwayGO:00071663250.013
regulation of calcium ion transportGO:005192420.012
regulation of cellular protein catabolic processGO:190336210.012
dna templated transcription elongationGO:000635430.012
protein localization to plasma membraneGO:007265910.012
protein importGO:001703830.012
heterocycle biosynthetic processGO:00181302150.012
regulation of establishment of protein localizationGO:007020140.012
positive regulation of gtpase activityGO:004354710.012
synaptic growth at neuromuscular junctionGO:005112420.012
positive regulation of cellular component biogenesisGO:004408930.012
chemosensory behaviorGO:000763510.012
regulation of transcription dna templatedGO:00063552130.012
cell projection morphogenesisGO:00488582440.012
small gtpase mediated signal transductionGO:000726480.012
posterior lateral line system developmentGO:0048915460.012
neuron differentiationGO:00301823530.012
negative regulation of mapk cascadeGO:004340940.012
macromolecular complex disassemblyGO:003298410.012
stem cell proliferationGO:007208940.012
regulation of developmental processGO:00507932470.012
positive regulation of nucleotide catabolic processGO:003081310.012
sequestering of metal ionGO:005123830.012
fatty acid catabolic processGO:000906210.012
positive regulation of secretion by cellGO:190353210.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
phagocytosis engulfmentGO:000691110.012
anion transportGO:0006820380.011
female sex differentiationGO:004666040.011
determination of heart left right asymmetryGO:00613711170.011
chloride transmembrane transportGO:190247640.011
membrane invaginationGO:001032410.011
b cell differentiationGO:003018310.011
cognitionGO:005089010.011
biosynthetic processGO:00090582940.011
cell morphogenesis involved in differentiationGO:00009041950.011
glucose homeostasisGO:004259310.011
regulation of response to stimulusGO:00485832690.011
regulation of protein polymerizationGO:003227120.011
positive regulation of camp biosynthetic processGO:003081920.011
nuclear pore organizationGO:000699920.011
spermatid developmentGO:000728620.011
cellular response to reactive oxygen speciesGO:003461420.011
endocrine hormone secretionGO:006098620.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
heart developmentGO:00075073130.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
establishment of localization in cellGO:0051649770.011
small molecule catabolic processGO:004428230.011
cellular component biogenesisGO:00440851780.011
regulation of protein targetingGO:190353320.011
regulation of i kappab kinase nf kappab signalingGO:004312240.011
regulation of metal ion transportGO:001095940.011
apoptotic process involved in developmentGO:190274220.011
purine nucleoside monophosphate catabolic processGO:000912840.011
determination of bilateral symmetryGO:00098552040.011
cellular lipid catabolic processGO:004424230.011
response to corticosteroidGO:003196010.011
regulation of metabolic processGO:00192223590.011
lipid oxidationGO:003444010.011
synaptic vesicle localizationGO:009747910.011
neuromuscular synaptic transmissionGO:000727420.011
response to xenobiotic stimulusGO:0009410450.011
regulation of cellular biosynthetic processGO:00313262450.011
response to external stimulusGO:00096052640.011
positive regulation of cytoskeleton organizationGO:005149530.011
regulation of cell substrate adhesionGO:001081010.011
regulation of apoptotic processGO:0042981980.011
vasculature developmentGO:00019442780.011
multicellular organismal signalingGO:0035637220.011
axon developmentGO:00615641660.011
sensory system developmentGO:0048880760.011
regulation of protein ubiquitinationGO:003139630.011
cellular response to starvationGO:000926710.011
mitotic cell cycleGO:0000278640.011
mitotic dna integrity checkpointGO:004477440.011
organic substance transportGO:0071702580.011
lymphangiogenesisGO:0001946250.011
skeletal muscle tissue developmentGO:0007519670.011
multicellular organismal metabolic processGO:004423620.011
intracellular mrna localizationGO:000829810.011
calcium ion transport into cytosolGO:006040230.011
specification of symmetryGO:00097992040.011
negative regulation of macromolecule metabolic processGO:0010605760.010
regulation of skeletal muscle tissue developmentGO:004864140.010
phosphate containing compound metabolic processGO:00067961080.010
negative regulation of reproductive processGO:200024230.010
mononuclear cell proliferationGO:003294310.010
regulation of catalytic activityGO:0050790550.010
negative regulation of cytokine productionGO:000181810.010
fatty acid transportGO:001590810.010
cytokinesisGO:000091030.010
lateral line developmentGO:0048882660.010
sensory perception of chemical stimulusGO:000760630.010
regulation of myotube differentiationGO:001083020.010
cell proliferation involved in heart morphogenesisGO:006132320.010
regulation of cellular component sizeGO:0032535300.010
ribonucleoside monophosphate catabolic processGO:000915840.010
mitotic dna damage checkpointGO:004477340.010
response to ketoneGO:190165410.010
actin filament polymerizationGO:003004120.010
negative regulation of cytoplasmic transportGO:190365020.010
regulation of organ morphogenesisGO:2000027350.010
embryonic organ morphogenesisGO:00485622740.010
cation transportGO:0006812810.010
negative regulation of protein serine threonine kinase activityGO:007190120.010
regulation of mrna processingGO:005068430.010
organic anion transportGO:0015711150.010
cellular protein metabolic processGO:00442671290.010
zinc ion homeostasisGO:005506910.010
synaptic vesicle recyclingGO:003646510.010
regulation of dna templated transcription elongationGO:003278430.010
regulation of protein import into nucleusGO:004230620.010

blm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
nervous system diseaseDOID:86300.018
immune system diseaseDOID:291400.016
organ system cancerDOID:005068600.016
cancerDOID:16200.016
disease of cellular proliferationDOID:1456600.016
musculoskeletal system diseaseDOID:1700.014
muscular diseaseDOID:008000000.013
muscle tissue diseaseDOID:6600.013
sensory system diseaseDOID:005015500.011
eye diseaseDOID:561400.011
retinal diseaseDOID:567900.011
eye and adnexa diseaseDOID:149200.011
retinal degenerationDOID:846600.010