Danio rerio

27 known processes

hoxb8a

homeo box B8a

(Aliases: gp-8,wu:fj67g02,hoxb8,fj67g02,zgc:64159)

hoxb8a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
posterior lateral line neuromast primordium migrationGO:0048920120.999
neuromast primordium migrationGO:0048883120.998
endocrine pancreas developmentGO:0031018270.996
Zebrafish
pancreas developmentGO:0031016840.983
Zebrafish
posterior lateral line system developmentGO:0048915460.978
posterior lateral line developmentGO:0048916380.968
mechanosensory lateral line system developmentGO:0048881490.956
cell fate specificationGO:0001708680.952
Zebrafish
lateral line developmentGO:0048882660.947
exocrine pancreas developmentGO:0031017280.945
Zebrafish
lateral line system developmentGO:0048925760.927
digestive system developmentGO:00551232890.893
Zebrafish
endocrine system developmentGO:0035270650.893
Zebrafish
pectoral fin developmentGO:0033339500.892
Zebrafish
sensory system developmentGO:0048880760.876
nucleobase containing compound biosynthetic processGO:00346542050.863
pectoral fin morphogenesisGO:0035138290.828
Zebrafish
fin morphogenesisGO:0033334530.778
Zebrafish
central nervous system developmentGO:00074173870.721
Zebrafish Mouse
locomotionGO:00400113130.695
cell migrationGO:00164772370.684
cell fate commitmentGO:0045165990.650
Zebrafish
localization of cellGO:00516742440.595
cardiocyte differentiationGO:0035051440.591
Zebrafish
exocrine system developmentGO:0035272280.585
Zebrafish
stem cell differentiationGO:00488631170.579
Zebrafish
appendage morphogenesisGO:0035107560.547
Zebrafish
fin developmentGO:0033333770.532
Zebrafish
embryonic appendage morphogenesisGO:0035113300.504
Zebrafish
organic substance biosynthetic processGO:19015762890.496
cellular component movementGO:00069283350.490
anterior posterior pattern specificationGO:00099521520.476
Mouse
regulation of rna metabolic processGO:00512522240.445
cell motilityGO:00488702440.437
embryonic pectoral fin morphogenesisGO:0035118240.401
Zebrafish
branching morphogenesis of an epithelial tubeGO:0048754150.383
appendage developmentGO:0048736800.376
Zebrafish
rna metabolic processGO:00160702190.371
head developmentGO:00603223030.371
Zebrafish
heterocycle metabolic processGO:00464832900.357
brain developmentGO:00074202930.349
Zebrafish
organic cyclic compound metabolic processGO:19013603010.328
regulation of nucleobase containing compound metabolic processGO:00192192500.325
nucleic acid templated transcriptionGO:00976591810.308
regulation of cellular biosynthetic processGO:00313262450.282
cellular macromolecule biosynthetic processGO:00346452240.251
heterocycle biosynthetic processGO:00181302150.240
rna biosynthetic processGO:00327741810.226
cellular nitrogen compound metabolic processGO:00346412900.215
negative regulation of cellular biosynthetic processGO:0031327550.210
transcription dna templatedGO:00063511810.202
regulation of cellular metabolic processGO:00313233200.194
regulation of nitrogen compound metabolic processGO:00511712510.192
cerebellar granular layer formationGO:002168430.191
pancreatic a cell developmentGO:000332220.183
nitrogen compound metabolic processGO:00068073190.179
regulation of macromolecule biosynthetic processGO:00105562250.176
epidermal cell fate specificationGO:000995740.174
cardioblast differentiationGO:001000290.173
Zebrafish
organic cyclic compound biosynthetic processGO:19013622230.170
cellular nitrogen compound biosynthetic processGO:00442712180.169
gene expressionGO:00104672520.165
regulation of epithelial cell proliferationGO:005067830.165
cerebellar granular layer morphogenesisGO:002168330.163
chordate embryonic developmentGO:00430092710.163
Mouse
embryo development ending in birth or egg hatchingGO:00097922710.152
Mouse
glial cell migrationGO:000834730.146
regulation of cellular macromolecule biosynthetic processGO:20001122220.144
tube morphogenesisGO:00352393490.138
cellular macromolecule metabolic processGO:00442603910.130
positive regulation of epithelial cell proliferationGO:005067910.125
embryonic organ developmentGO:00485683810.124
Mouse
neuromast developmentGO:0048884460.123
regulation of biosynthetic processGO:00098892500.120
heart developmentGO:00075073130.116
Zebrafish
pharyngeal muscle developmentGO:004328240.111
erythrocyte differentiationGO:0030218540.111
pancreatic d cell differentiationGO:000331120.109
nucleic acid metabolic processGO:00903042440.104
negative regulation of myeloid cell differentiationGO:004563810.103
Mouse
renal tubule morphogenesisGO:006133310.102
cell proliferationGO:0008283800.102
immune system processGO:00023762410.101
Mouse
cerebellar granule cell differentiationGO:002170730.101
regulation of stem cell proliferationGO:007209120.100
mesodermal cell fate specificationGO:0007501120.097
negative regulation of biological processGO:00485193040.093
Mouse
regulation of gene expressionGO:00104682650.093
regulation of cell fate specificationGO:0042659200.090
regulation of macromolecule metabolic processGO:00602553170.090
photoreceptor cell fate specificationGO:004370410.088
cellular ketone metabolic processGO:0042180110.087
skeletal system morphogenesisGO:00487051020.086
Mouse
regulation of transcription dna templatedGO:00063552130.083
homeostasis of number of cellsGO:0048872620.083
eye morphogenesisGO:00485921440.082
nucleobase containing compound metabolic processGO:00061392740.081
cellular biosynthetic processGO:00442492860.080
larval developmentGO:000216420.080
transcription from rna polymerase ii promoterGO:0006366800.079
somatic stem cell maintenanceGO:003501910.077
type b pancreatic cell developmentGO:000332340.076
regulation of mesodermal cell fate specificationGO:004266190.074
negative regulation of rna biosynthetic processGO:1902679450.073
single organism metabolic processGO:00447102170.073
negative regulation of cellular processGO:00485232830.072
Mouse
cellular aromatic compound metabolic processGO:00067252950.072
cell fate specification involved in pattern specificationGO:006057330.072
midbrain hindbrain boundary developmentGO:0030917230.070
regulation of rna biosynthetic processGO:20011412130.068
agingGO:000756820.064
cellular amine metabolic processGO:004410620.064
ventral spinal cord interneuron fate commitmentGO:006057930.063
epithelial cell differentiationGO:00308551160.061
positive regulation of jak stat cascadeGO:004642720.061
apoptotic process involved in developmentGO:190274220.060
morphogenesis of a branching structureGO:0001763210.060
neuron fate specificationGO:0048665200.058
regulation of metabolic processGO:00192223590.056
mesodermal cell differentiationGO:0048333210.056
ventral spinal cord interneuron specificationGO:002152130.055
nephron epithelium morphogenesisGO:007208810.055
negative regulation of nitrogen compound metabolic processGO:0051172590.055
regionalizationGO:00030022740.055
Mouse
generation of neuronsGO:00486993850.055
astrocyte differentiationGO:004870810.054
regulation of transcription from rna polymerase ii promoterGO:00063571140.053
aromatic compound biosynthetic processGO:00194382170.053
hindbrain developmentGO:0030902910.052
myeloid cell differentiationGO:0030099860.051
Mouse
regulation of nucleic acid templated transcriptionGO:19035062130.050
development of primary female sexual characteristicsGO:004654540.048
central nervous system myelinationGO:002201020.048
forebrain anterior posterior pattern specificationGO:002179730.047
stem cell proliferationGO:007208940.047
regulation of multicellular organismal processGO:00512392770.047
Mouse
carboxylic acid metabolic processGO:0019752220.046
keratinocyte differentiationGO:003021600.045
mesodermal cell fate commitmentGO:0001710140.045
cellular amino acid metabolic processGO:000652070.045
neuron fate determinationGO:004866420.045
negative regulation of biosynthetic processGO:0009890550.044
response to glucocorticoidGO:005138410.044
regulation of jak stat cascadeGO:004642530.044
regulation of vasculogenesisGO:200121210.043
epithelial cell morphogenesisGO:000338220.041
negative regulation of gene expressionGO:0010629650.041
blood vessel developmentGO:00015682460.041
cell migration in hindbrainGO:002153570.041
vestibular receptor cell developmentGO:006011830.040
peptide transportGO:001583310.040
regulation of primary metabolic processGO:00800903110.040
regulation of cell proliferation involved in heart morphogenesisGO:200013620.040
positive regulation of cell fate commitmentGO:001045510.040
regulation of organ morphogenesisGO:2000027350.040
neuroblast proliferationGO:000740520.039
peripheral nervous system developmentGO:0007422550.039
erythrocyte homeostasisGO:0034101550.039
nephron developmentGO:0072006310.039
response to ketoneGO:190165410.038
regulation of cellular ketone metabolic processGO:001056570.038
embryonic organ morphogenesisGO:00485622740.037
Mouse
cerebellar granular layer developmentGO:002168130.037
hemopoiesisGO:00300971830.037
Mouse
positive regulation of nitrogen compound metabolic processGO:0051173690.037
epithelial tube morphogenesisGO:00605621480.037
sensory organ developmentGO:00074233930.036
positive regulation of metabolic processGO:00098931080.036
organelle organizationGO:00069962270.035
cell proliferation involved in heart morphogenesisGO:006132320.035
endothelial cell differentiationGO:0045446200.034
negative regulation of macromolecule biosynthetic processGO:0010558480.034
apoptotic process involved in morphogenesisGO:006056120.034
morphogenesis of an epithelial sheetGO:0002011490.033
epithelial cell morphogenesis involved in gastrulationGO:000338110.033
morphogenesis of a branching epitheliumGO:0061138160.032
biosynthetic processGO:00090582940.032
somatic muscle developmentGO:000752540.032
positive regulation of cell cycleGO:004578730.032
nephron tubule morphogenesisGO:007207810.031
neural crest cell migrationGO:0001755420.031
negative regulation of transcription dna templatedGO:0045892450.031
endothelium developmentGO:0003158250.031
macromolecule biosynthetic processGO:00090592270.031
cell differentiation in hindbrainGO:002153350.031
somitogenesisGO:0001756870.031
negative regulation of signal transduction in absence of ligandGO:190109910.031
retina development in camera type eyeGO:00600411460.030
response to hormoneGO:0009725480.030
regulation of neurogenesisGO:0050767870.030
neural keel formationGO:001402510.030
fertilizationGO:000956630.030
regulation of cell fate commitmentGO:0010453220.030
positive regulation of nucleobase containing compound metabolic processGO:0045935690.029
positive regulation of cellular processGO:00485222010.029
regulation of neural precursor cell proliferationGO:200017730.029
negative regulation of epithelial to mesenchymal transitionGO:001071910.029
embryonic retina morphogenesis in camera type eyeGO:0060059220.029
diterpenoid biosynthetic processGO:001610270.029
intracellular signal transductionGO:0035556850.029
developmental programmed cell deathGO:001062340.029
spinal cord oligodendrocyte cell fate specificationGO:002153020.029
mesoderm morphogenesisGO:0048332510.028
regulation of glial cell differentiationGO:004568540.028
regulation of inner ear receptor cell differentiationGO:200098010.028
female sex differentiationGO:004666040.028
olfactory placode developmentGO:0071698120.028
cardiac chamber formationGO:000320740.028
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.027
positive regulation of cellular amino acid metabolic processGO:004576400.027
negative regulation of metabolic processGO:0009892860.027
camera type eye morphogenesisGO:00485931080.026
regulation of gastrulationGO:0010470240.026
blood circulationGO:0008015870.026
ventricular system developmentGO:0021591120.026
cell cycle g1 s phase transitionGO:004484310.026
rhombomere 4 morphogenesisGO:002166150.025
epithelial cell developmentGO:0002064420.025
skin developmentGO:0043588540.025
hormone transportGO:000991420.025
regulation of mechanoreceptor differentiationGO:004563110.024
regulation of cell developmentGO:00602841000.024
embryonic skeletal system developmentGO:0048706970.023
Mouse
response to corticosteroidGO:003196010.023
digestive tract morphogenesisGO:00485462310.023
amine metabolic processGO:000930820.023
organic acid metabolic processGO:0006082310.022
negative regulation of rna metabolic processGO:0051253480.022
positive regulation of cellular amine metabolic processGO:003324000.022
lymphangiogenesisGO:0001946250.022
positive regulation of canonical wnt signaling pathwayGO:009026340.022
negative regulation of nucleobase containing compound metabolic processGO:0045934590.021
cranial ganglion developmentGO:006155030.021
cellular response to starvationGO:000926710.021
entrainment of circadian clockGO:000964920.021
ventral spinal cord interneuron differentiationGO:0021514120.021
positive regulation of neural precursor cell proliferationGO:200017910.021
neural tube patterningGO:0021532330.021
positive regulation of stem cell proliferationGO:200064810.021
regulation of cellular amino acid metabolic processGO:000652100.021
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.021
hematopoietic or lymphoid organ developmentGO:00485341910.021
Mouse
regulation of cell differentiationGO:00455951420.021
Mouse
peripheral nervous system neuron developmentGO:0048935220.021
neuromuscular process controlling balanceGO:005088530.020
vasculature developmentGO:00019442780.020
nose developmentGO:004358430.020
single organism organelle organizationGO:19025891990.020
specification of organ identityGO:001009220.020
positive regulation of cellular metabolic processGO:0031325940.020
innervationGO:006038430.020
kidney developmentGO:0001822920.020
positive regulation of rna metabolic processGO:0051254590.020
regulation of tyrosine phosphorylation of stat3 proteinGO:004251610.020
blood vessel morphogenesisGO:00485142160.020
liver developmentGO:0001889960.020
positive regulation of tyrosine phosphorylation of stat3 proteinGO:004251710.020
regulation of stem cell differentiationGO:200073640.019
peptide metabolic processGO:000651810.019
gabaergic neuron differentiationGO:009715420.019
olfactory placode formationGO:003091010.019
regulation of anatomical structure morphogenesisGO:00226031300.019
embryonic skeletal system morphogenesisGO:0048704930.019
Mouse
stem cell maintenanceGO:001982740.019
gastrulationGO:00073692080.018
regulation of cardiac chamber formationGO:190121020.018
cardiac atrium morphogenesisGO:000320920.018
negative regulation of endothelial cell migrationGO:001059610.018
muscle cell differentiationGO:00426921390.018
regulation of apoptotic processGO:0042981980.018
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.018
hepaticobiliary system developmentGO:0061008980.017
positive regulation of mesenchymal cell proliferationGO:000205310.017
regulation of peptidyl tyrosine phosphorylationGO:005073010.017
cell morphogenesisGO:00009022890.017
regulation of cellular amine metabolic processGO:003323800.016
regulation of erythrocyte differentiationGO:004564620.016
rhombomere 4 developmentGO:002157050.016
immune system developmentGO:00025201910.016
Mouse
neuron differentiationGO:00301823530.016
pharynx developmentGO:006046550.016
retina morphogenesis in camera type eyeGO:0060042790.016
regulation of signalingGO:00230512350.016
negative regulation of cellular metabolic processGO:0031324770.016
wnt signaling pathway involved in somitogenesisGO:009024420.016
g1 s transition of mitotic cell cycleGO:000008210.015
stem cell divisionGO:001714510.015
extrinsic apoptotic signaling pathwayGO:009719130.015
establishment of localizationGO:00512342440.015
regulation of extrinsic apoptotic signaling pathwayGO:200123630.015
proximal distal pattern formationGO:000995410.015
positive regulation of notch signaling pathwayGO:004574730.015
single fertilizationGO:000733830.015
cerebellar cortex formationGO:002169750.015
regulation of cell migrationGO:0030334400.015
positive regulation of rna biosynthetic processGO:1902680570.015
endothelial cell fate commitmentGO:006083930.015
cell cycleGO:0007049930.015
positive regulation of macromolecule metabolic processGO:0010604930.015
positive regulation of jnk cascadeGO:004633030.015
endothelial cell proliferationGO:0001935110.015
canonical wnt signaling pathwayGO:0060070480.015
programmed cell deathGO:00125011190.015
type b pancreatic cell differentiationGO:000330980.014
muscle cell migrationGO:001481240.014
mesenchymal cell developmentGO:0014031780.014
transcription from rna polymerase iii promoterGO:000638310.014
skeletal system developmentGO:00015011810.014
Mouse
hypochord developmentGO:005501630.014
negative regulation of mesodermal cell fate specificationGO:004266230.014
cellular response to extracellular stimulusGO:003166820.014
regulation of mesoderm developmentGO:2000380110.014
cellular amide metabolic processGO:004360340.014
patterning of lymph vesselsGO:006085410.014
skeletal muscle organ developmentGO:0060538780.014
dendrite guidanceGO:007098300.013
posterior lateral line neuromast developmentGO:0048919200.013
positive regulation of cellular biosynthetic processGO:0031328680.013
negative regulation of nucleic acid templated transcriptionGO:1903507450.013
regulation of neuron migrationGO:200122220.013
angiogenesisGO:00015251580.013
kidney morphogenesisGO:0060993150.013
definitive hemopoiesisGO:0060216180.013
regulation of epithelial to mesenchymal transitionGO:001071730.013
blood vessel endothelial cell proliferation involved in sprouting angiogenesisGO:000204340.013
embryonic viscerocranium morphogenesisGO:0048703520.013
neuroblast differentiationGO:001401610.013
embryonic camera type eye morphogenesisGO:0048596190.013
otolith developmentGO:0048840320.013
compound eye developmentGO:004874920.013
aorta developmentGO:003590440.013
pigment cell differentiationGO:0050931380.013
regulation of isoprenoid metabolic processGO:001974760.013
regulation of canonical wnt signaling pathwayGO:0060828340.013
negative regulation of response to cytokine stimulusGO:006076120.012
myotome developmentGO:006105510.012
ectoderm formationGO:000170520.012
rostrocaudal neural tube patterningGO:0021903290.012
sensory organ morphogenesisGO:00905962000.012
glomerulus vasculature morphogenesisGO:007210310.012
eye developmentGO:00016542770.012
striated muscle cell differentiationGO:00511461290.012
hematopoietic stem cell differentiationGO:0060218200.012
notch signaling pathwayGO:0007219350.012
activation of mapk activityGO:000018730.012
regulation of biological qualityGO:00650082630.012
regulation of alternative mrna splicing via spliceosomeGO:000038110.012
negative regulation of macromolecule metabolic processGO:0010605760.012
positive regulation of glial cell differentiationGO:004568710.012
cell proliferation in forebrainGO:002184630.012
regulation of hormone secretionGO:004688320.012
olfactory bulb developmentGO:002177240.012
embryonic eye morphogenesisGO:0048048300.012
neuron developmentGO:00486662620.012
regulation of programmed cell deathGO:00430671010.012
pancreatic d cell developmentGO:000332410.012
regenerationGO:0031099910.012
oxoacid metabolic processGO:0043436310.012
neuromast hair cell differentiationGO:0048886120.012
glomerulus developmentGO:0032835270.012
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.012
pancreatic a cell differentiationGO:000331060.012
intracellular estrogen receptor signaling pathwayGO:003052030.012
neuroblast fate commitmentGO:001401710.011
cellular response to nutrient levelsGO:003166920.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.011
posterior lateral line neuromast mantle cell differentiationGO:004892410.011
inner ear receptor cell differentiationGO:0060113290.011
glucose homeostasisGO:004259310.011
fourth ventricle developmentGO:002159280.011
homeostatic processGO:00425921420.011
mesenchyme developmentGO:00604851270.011
peripheral nervous system neuron differentiationGO:0048934280.011
carbohydrate homeostasisGO:003350010.011
glial cell fate specificationGO:002178040.011
primitive hemopoiesisGO:0060215270.011
neuron migrationGO:0001764220.011
regulation of endothelial cell proliferationGO:000193610.011
neural tube developmentGO:0021915620.011
forebrain developmentGO:0030900960.011
lipid storageGO:001991510.011
hormone secretionGO:004687920.011
commissural neuron axon guidanceGO:007167930.011
ventricular cardiac muscle tissue developmentGO:000322930.011
multicellular organism growthGO:003526440.011
photoreceptor cell fate commitmentGO:004655210.011
membrane fusionGO:006102520.011
regulation of multicellular organismal developmentGO:20000262230.011
Mouse
olfactory lobe developmentGO:002198840.011
cardiac atrium developmentGO:000323040.011
axon developmentGO:00615641660.011
positive regulation of myeloid cell differentiationGO:004563920.011
regulation of neural retina developmentGO:006107420.011
thyroid gland developmentGO:0030878120.010
positive regulation of gene expressionGO:0010628710.010
positive regulation of stress activated mapk cascadeGO:003287430.010
inner ear developmentGO:00488391260.010
proepicardium developmentGO:000334240.010
regulation of retina development in camera type eyeGO:190286620.010
cell morphogenesis involved in differentiationGO:00009041950.010
cell deathGO:00082191210.010
forebrain regionalizationGO:002187140.010
regulation of tyrosine phosphorylation of stat proteinGO:004250910.010
lymph vessel developmentGO:0001945270.010
embryonic heart tube developmentGO:00350501330.010
epidermis morphogenesisGO:004873040.010
eye photoreceptor cell differentiationGO:0001754450.010
tissue regenerationGO:0042246740.010

hoxb8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.035
cancerDOID:16200.035
gastrointestinal system cancerDOID:311900.035
intestinal cancerDOID:1015500.035
colon cancerDOID:21900.035
large intestine cancerDOID:567200.035
colon carcinomaDOID:152000.035
colorectal cancerDOID:925600.035
organ system cancerDOID:005068600.035
nonsyndromic deafnessDOID:005056300.032
disease of anatomical entityDOID:700.032
auditory system diseaseDOID:274200.032
sensory system diseaseDOID:005015500.032
autosomal dominant nonsyndromic deafnessDOID:005056400.032
nervous system diseaseDOID:86300.032
musculoskeletal system diseaseDOID:1700.011