Danio rerio

11 known processes

sesn1

sestrin 1

(Aliases: zgc:91970)

sesn1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular macromolecule biosynthetic processGO:20001122220.943
regulation of gene expressionGO:00104682650.903
specification of symmetryGO:00097992040.893
cellular macromolecule biosynthetic processGO:00346452240.878
regulation of transcription dna templatedGO:00063552130.860
aromatic compound biosynthetic processGO:00194382170.836
regulation of rna biosynthetic processGO:20011412130.833
nucleic acid metabolic processGO:00903042440.825
regulation of rna metabolic processGO:00512522240.809
gene expressionGO:00104672520.784
regulation of cellular biosynthetic processGO:00313262450.777
determination of bilateral symmetryGO:00098552040.769
regulation of macromolecule biosynthetic processGO:00105562250.756
signal transductionGO:00071654550.724
organic substance biosynthetic processGO:19015762890.714
regulation of nucleic acid templated transcriptionGO:19035062130.714
transcription dna templatedGO:00063511810.686
regulation of cellular metabolic processGO:00313233200.635
cellular biosynthetic processGO:00442492860.630
regulation of nitrogen compound metabolic processGO:00511712510.626
cellular nitrogen compound biosynthetic processGO:00442712180.624
nucleobase containing compound biosynthetic processGO:00346542050.616
heterocycle metabolic processGO:00464832900.598
regulation of metabolic processGO:00192223590.593
regulation of nucleobase containing compound metabolic processGO:00192192500.580
rna biosynthetic processGO:00327741810.571
cellular macromolecule metabolic processGO:00442603910.564
digestive tract developmentGO:00485652650.562
regulation of biosynthetic processGO:00098892500.560
cellular nitrogen compound metabolic processGO:00346412900.529
regulation of primary metabolic processGO:00800903110.504
organic cyclic compound biosynthetic processGO:19013622230.496
nephron tubule morphogenesisGO:007207810.493
negative regulation of gene expressionGO:0010629650.476
nucleobase containing compound metabolic processGO:00061392740.470
macromolecule biosynthetic processGO:00090592270.463
nucleic acid templated transcriptionGO:00976591810.452
somitogenesisGO:0001756870.452
cellular aromatic compound metabolic processGO:00067252950.423
rna metabolic processGO:00160702190.399
determination of left right symmetryGO:00073681790.396
heterocycle biosynthetic processGO:00181302150.392
digestive system developmentGO:00551232890.379
cell surface receptor signaling pathwayGO:00071663250.373
nitrogen compound metabolic processGO:00068073190.370
regulation of macromolecule metabolic processGO:00602553170.355
somite developmentGO:0061053960.347
erythrocyte maturationGO:004324980.343
convergent extensionGO:00600261180.321
positive regulation of epithelial cell differentiationGO:003085820.296
negative regulation of transcription dna templatedGO:0045892450.293
central nervous system developmentGO:00074173870.287
compound eye developmentGO:004874920.280
biosynthetic processGO:00090582940.259
somite rostral caudal axis specificationGO:003252550.248
brain developmentGO:00074202930.243
regionalizationGO:00030022740.230
transcription from rna polymerase ii promoterGO:0006366800.216
organic cyclic compound metabolic processGO:19013603010.214
embryonic organ morphogenesisGO:00485622740.210
negative regulation of rna biosynthetic processGO:1902679450.208
positive regulation of gene expressionGO:0010628710.205
positive regulation of nucleic acid templated transcriptionGO:1903508570.204
digestive tract morphogenesisGO:00485462310.198
gastrulationGO:00073692080.192
negative regulation of nucleic acid templated transcriptionGO:1903507450.192
neuron developmentGO:00486662620.187
negative regulation of biosynthetic processGO:0009890550.185
midbrain hindbrain boundary developmentGO:0030917230.184
cardiac chamber formationGO:000320740.184
negative regulation of rna metabolic processGO:0051253480.179
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.166
regulation of transcription from rna polymerase ii promoterGO:00063571140.164
positive regulation of biological processGO:00485182530.158
negative regulation of biological processGO:00485193040.156
regulation of cell differentiationGO:00455951420.156
bmp signaling pathwayGO:0030509520.155
hematopoietic or lymphoid organ developmentGO:00485341910.154
immune system developmentGO:00025201910.153
cell migration involved in gastrulationGO:0042074790.152
segmentationGO:0035282970.149
pronephros developmentGO:0048793690.149
localization of cellGO:00516742440.143
heart developmentGO:00075073130.143
negative regulation of cellular processGO:00485232830.135
notch signaling pathwayGO:0007219350.134
generation of neuronsGO:00486993850.132
chordate embryonic developmentGO:00430092710.129
muscle structure developmentGO:00610611960.128
muscle tissue developmentGO:00605371100.127
negative regulation of macromolecule biosynthetic processGO:0010558480.126
cell morphogenesis involved in neuron differentiationGO:00486671630.125
negative regulation of nitrogen compound metabolic processGO:0051172590.117
heart field specificationGO:000312810.116
negative regulation of multicellular organismal processGO:0051241690.115
radial glial cell differentiationGO:006001920.111
cellular component movementGO:00069283350.107
hemopoiesisGO:00300971830.105
positive regulation of transcription dna templatedGO:0045893570.103
negative regulation of cellular biosynthetic processGO:0031327550.103
regulation of bmp signaling pathwayGO:0030510390.103
anterior posterior pattern specificationGO:00099521520.102
homeostasis of number of cellsGO:0048872620.102
negative regulation of nucleobase containing compound metabolic processGO:0045934590.100
convergent extension involved in organogenesisGO:0060029100.100
morphogenesis of an epitheliumGO:00020093330.096
cardiac conduction system developmentGO:000316110.095
negative regulation of macromolecule metabolic processGO:0010605760.093
positive regulation of rna metabolic processGO:0051254590.092
enzyme linked receptor protein signaling pathwayGO:00071671060.091
renal system developmentGO:0072001940.087
regulation of notch signaling pathwayGO:0008593160.087
gastrulation with mouth forming secondGO:0001702440.086
cell motilityGO:00488702440.085
nephron epithelium morphogenesisGO:007208810.084
positive regulation of striated muscle cell differentiationGO:005115510.083
aorta developmentGO:003590440.083
cilium morphogenesisGO:0060271850.083
skeletal system developmentGO:00015011810.078
striated muscle cell differentiationGO:00511461290.078
limb bud formationGO:006017420.077
embryonic organ developmentGO:00485683810.076
epithelial tube morphogenesisGO:00605621480.076
hepatocyte differentiationGO:007036510.073
heart loopingGO:0001947940.072
positive regulation of nitrogen compound metabolic processGO:0051173690.072
skeletal muscle organ developmentGO:0060538780.071
neuron differentiationGO:00301823530.070
positive regulation of cellular biosynthetic processGO:0031328680.070
cell migrationGO:00164772370.070
skeletal system morphogenesisGO:00487051020.068
epibolyGO:0090504410.067
somite specificationGO:0001757120.067
locomotionGO:00400113130.066
negative regulation of cellular metabolic processGO:0031324770.065
head developmentGO:00603223030.064
negative regulation of mesoderm developmentGO:200038150.064
positive regulation of notch signaling pathwayGO:004574730.062
regulation of signal transductionGO:00099662250.062
positive regulation of rna biosynthetic processGO:1902680570.060
striated muscle tissue developmentGO:00147061100.059
negative regulation of cell differentiationGO:0045596460.059
formation of primary germ layerGO:0001704620.059
regulation of multicellular organismal developmentGO:20000262230.058
response to stressGO:00069502630.058
sensory organ developmentGO:00074233930.056
vasculature developmentGO:00019442780.056
negative regulation of mesodermal cell fate specificationGO:004266230.055
cellular component assemblyGO:00226071700.055
proepicardium developmentGO:000334240.055
renal tubule morphogenesisGO:006133310.055
maintenance of locationGO:005123540.054
nephron developmentGO:0072006310.053
auditory receptor cell fate commitmentGO:000991240.053
myeloid cell differentiationGO:0030099860.053
positive regulation of nucleobase containing compound metabolic processGO:0045935690.053
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.053
regulation of myotube differentiationGO:001083020.053
regulation of signalingGO:00230512350.052
tube morphogenesisGO:00352393490.052
developmental growthGO:00485891660.051
regulation of reproductive processGO:200024140.051
inner ear developmentGO:00488391260.051
glomerulus developmentGO:0032835270.049
biological adhesionGO:0022610400.048
nephron morphogenesisGO:007202820.048
hepaticobiliary system developmentGO:0061008980.048
positive regulation of bmp signaling pathwayGO:0030513100.048
regulation of inner ear receptor cell differentiationGO:200098010.048
larval developmentGO:000216420.048
epidermis developmentGO:0008544480.047
negative regulation of metabolic processGO:0009892860.047
oocyte maturationGO:000155640.046
positive regulation of cell fate commitmentGO:001045510.046
positive regulation of transportGO:005105020.046
epithelial cell differentiationGO:00308551160.045
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.045
ectodermal placode morphogenesisGO:0071697320.045
regulation of wnt signaling pathwayGO:0030111530.044
cardiac atrium morphogenesisGO:000320920.043
positive regulation of macromolecule metabolic processGO:0010604930.043
ossificationGO:0001503230.043
post anal tail morphogenesisGO:0036342190.042
blood vessel developmentGO:00015682460.041
bone morphogenesisGO:0060349110.041
female gonad developmentGO:000858540.041
response to monosaccharideGO:003428430.041
cell projection organizationGO:00300302840.041
protein metabolic processGO:00195381830.040
morphogenesis of an epithelial sheetGO:0002011490.040
endoderm developmentGO:0007492490.040
response to abiotic stimulusGO:00096281220.040
cell morphogenesisGO:00009022890.039
positive regulation of metabolic processGO:00098931080.039
regulation of hematopoietic progenitor cell differentiationGO:190153210.037
atrial ventricular junction remodelingGO:000329420.037
mesoderm formationGO:0001707430.036
macromolecular complex subunit organizationGO:0043933740.036
retina morphogenesis in camera type eyeGO:0060042790.036
glomerular basement membrane developmentGO:003283650.036
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.036
anterior posterior axis specificationGO:0009948200.036
endothelial cell fate commitmentGO:006083930.035
blood vessel morphogenesisGO:00485142160.035
positive regulation of response to stimulusGO:0048584800.035
mesodermal to mesenchymal transition involved in gastrulationGO:006080910.035
negative regulation of embryonic developmentGO:0045992110.034
erythrocyte differentiationGO:0030218540.034
negative regulation of reproductive processGO:200024230.034
positive regulation of tyrosine phosphorylation of stat3 proteinGO:004251710.034
dorsal ventral pattern formationGO:00099531250.033
positive regulation of macromolecule biosynthetic processGO:0010557590.033
cellular component biogenesisGO:00440851780.033
wnt signaling pathwayGO:0016055800.033
neuron projection developmentGO:00311751800.032
segment specificationGO:0007379120.031
circulatory system processGO:0003013870.031
cell migration involved in heart formationGO:0060974100.031
regulation of response to stimulusGO:00485832690.031
regulation of canonical wnt signaling pathwayGO:0060828340.031
kidney epithelium developmentGO:0072073230.031
immune system processGO:00023762410.031
heart joggingGO:0003146400.030
embryo development ending in birth or egg hatchingGO:00097922710.030
lymphatic endothelial cell differentiationGO:006083610.030
regulation of heart growthGO:006042020.030
pharyngeal muscle developmentGO:004328240.030
cardioblast migrationGO:000326070.030
erythrocyte homeostasisGO:0034101550.029
response to glucoseGO:000974930.029
lymphatic endothelial cell fate commitmentGO:006083810.029
skin developmentGO:0043588540.028
invagination involved in gastrulation with mouth forming secondGO:005510910.028
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.028
embryonic axis specificationGO:0000578120.028
cellular response to nutrient levelsGO:003166920.028
urogenital system developmentGO:0001655970.027
proximal distal pattern formationGO:000995410.027
notochord developmentGO:0030903540.026
myotube cell developmentGO:0014904350.026
regulation of establishment of protein localizationGO:007020140.025
fin developmentGO:0033333770.025
positive regulation of muscle tissue developmentGO:190186310.025
regulation of cell communicationGO:00106462320.025
positive regulation of muscle cell differentiationGO:005114910.025
regulation of stem cell proliferationGO:007209120.024
positive regulation of biosynthetic processGO:0009891680.024
developmental maturationGO:0021700340.023
regulation of neural precursor cell proliferationGO:200017730.023
cell fate commitmentGO:0045165990.023
neuronal stem cell maintenanceGO:009715020.023
regulation of collateral sprouting of intact axon in response to injuryGO:004868320.023
positive regulation of cellular metabolic processGO:0031325940.023
cell surface receptor signaling pathway involved in heart developmentGO:0061311200.023
ear morphogenesisGO:0042471640.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.022
negative regulation of signal transductionGO:0009968940.022
stem cell maintenanceGO:001982740.022
ventricular cardiac muscle tissue developmentGO:000322930.022
cardiac cell fate commitmentGO:006091110.022
response to chemicalGO:00422213200.022
determination of heart left right asymmetryGO:00613711170.022
positive regulation of canonical wnt signaling pathwayGO:009026340.022
regulation of gene expression epigeneticGO:0040029110.021
regulation of transcription from rna polymerase iii promoterGO:000635910.021
astrocyte differentiationGO:004870810.021
cell proliferationGO:0008283800.021
regulation of developmental processGO:00507932470.021
kidney developmentGO:0001822920.021
regulation of protein transportGO:005122330.020
rhombomere boundary formationGO:0021654100.020
regulation of epidermis developmentGO:004568220.020
nephron epithelium developmentGO:0072009160.020
ear developmentGO:00435831270.020
regulation of biological qualityGO:00650082630.020
cardiac ventricle formationGO:000321110.020
positive regulation of cell cycleGO:004578730.020
skeletal muscle tissue developmentGO:0007519670.020
cell morphogenesis involved in differentiationGO:00009041950.019
positive regulation of embryonic developmentGO:004001930.019
regulation of nervous system developmentGO:0051960900.019
intermediate mesoderm developmentGO:004838920.019
cell part morphogenesisGO:00329902460.019
stem cell differentiationGO:00488631170.019
negative regulation of gliogenesisGO:001401410.019
mesenchyme developmentGO:00604851270.019
regulation of cardiac muscle tissue developmentGO:005502410.019
regulation of synapse assemblyGO:005196330.019
cell migration to the midline involved in heart developmentGO:0003318120.019
cellular protein metabolic processGO:00442671290.019
muscle cell developmentGO:00550011150.019
extracellular matrix assemblyGO:008502910.019
regulation of blood vessel sizeGO:005088020.018
development of primary female sexual characteristicsGO:004654540.018
blood vessel endothelial cell differentiationGO:006083720.018
striated muscle cell developmentGO:00550021080.018
inner ear morphogenesisGO:0042472630.018
response to organic substanceGO:00100331530.018
arterial endothelial cell differentiationGO:006084220.018
regulation of protein complex assemblyGO:004325430.018
negative regulation of wnt signaling pathway involved in heart developmentGO:000330820.018
response to hexoseGO:000974630.018
negative regulation of protein complex assemblyGO:003133310.018
epithelial to mesenchymal transitionGO:0001837210.018
regulation of endodermal cell differentiationGO:1903224150.018
deathGO:00162651210.018
specification of organ positionGO:001015930.017
negative chemotaxisGO:005091910.017
positive regulation of cell communicationGO:0010647560.017
convergent extension involved in gastrulationGO:0060027710.017
negative regulation of protein transportGO:005122430.017
endothelial cell differentiationGO:0045446200.017
response to external stimulusGO:00096052640.017
negative regulation of developmental processGO:0051093650.017
septum transversum developmentGO:000334340.017
regulation of protein import into nucleusGO:004230620.017
cilium organizationGO:0044782710.017
tyrosine phosphorylation of stat3 proteinGO:004250310.017
female sex differentiationGO:004666040.017
negative regulation of cell communicationGO:0010648960.016
regulation of protein targetingGO:190353320.016
cardiac atrium developmentGO:000323040.016
neuron projection morphogenesisGO:00488121610.016
myotube differentiationGO:0014902450.016
single organism metabolic processGO:00447102170.016
pectoral fin morphogenesisGO:0035138290.016
somatic muscle developmentGO:000752540.016
optic placode formation involved in camera type eye formationGO:004661930.016
negative regulation of endodermal cell fate specificationGO:004266480.016
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.016
appendage morphogenesisGO:0035107560.016
negative regulation of canonical wnt signaling pathwayGO:0090090210.016
regulation of cellular amine metabolic processGO:003323800.016
positive regulation of neuron migrationGO:200122420.016
protein import into nucleusGO:000660630.015
growthGO:00400071740.015
centrosome cycleGO:000709810.015
endothelium developmentGO:0003158250.015
mesendoderm developmentGO:0048382100.015
cellular response to stressGO:0033554620.015
multicellular organism growthGO:003526440.015
single organism organelle organizationGO:19025891990.015
organelle assemblyGO:00709251100.015
determination of dorsal ventral asymmetryGO:0048262340.015
primitive hemopoiesisGO:0060215270.015
cilium assemblyGO:0042384580.015
regulation of skeletal muscle tissue developmentGO:004864140.015
eye photoreceptor cell developmentGO:0042462300.015
cellular component morphogenesisGO:00329893360.014
nuclear transportGO:005116940.014
positive regulation of stem cell proliferationGO:200064810.014
specification of organ identityGO:001009220.014
negative regulation of endodermal cell differentiationGO:190322580.014
centrosome organizationGO:005129710.014
axon ensheathment in central nervous systemGO:003229120.014
cell projection assemblyGO:0030031640.014
forebrain neuron differentiationGO:0021879140.014
myeloid cell homeostasisGO:0002262560.014
positive regulation of striated muscle tissue developmentGO:004584410.014
regulation of tyrosine phosphorylation of stat proteinGO:004250910.014
aorta morphogenesisGO:003590930.014
positive regulation of jak stat cascadeGO:004642720.014
protein importGO:001703830.014
b cell activationGO:004211320.014
negative regulation of gastrulationGO:2000542110.014
embryonic cranial skeleton morphogenesisGO:0048701900.014
negative regulation of nodal signaling pathwayGO:190010840.013
nephric duct developmentGO:0072176130.013
heart valve formationGO:000318840.013
embryonic pattern specificationGO:0009880440.013
regulation of anatomical structure morphogenesisGO:00226031300.013
cellular process involved in reproduction in multicellular organismGO:0022412280.013
non canonical wnt signaling pathway involved in heart developmentGO:006134120.013
cell fate commitment involved in formation of primary germ layerGO:0060795260.013
lymph vessel developmentGO:0001945270.013
germ cell developmentGO:0007281220.013
regulation of jak stat cascadeGO:004642530.013
spinal cord developmentGO:0021510460.013
muscle cell differentiationGO:00426921390.013
regulation of syncytium formation by plasma membrane fusionGO:006014220.012
pronephric duct developmentGO:0039022130.012
response to oxygen containing compoundGO:1901700550.012
regulation of circadian rhythmGO:004275240.012
regulation of cell proliferation involved in heart morphogenesisGO:200013620.012
regulation of gastrulationGO:0010470240.012
cell proliferation in forebrainGO:002184630.012
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.012
intra s dna damage checkpointGO:003157310.012
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.012
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.012
positive regulation of skeletal muscle tissue developmentGO:004864310.012
cardioblast migration to the midline involved in heart field formationGO:006097570.012
determination of left right asymmetry in diencephalonGO:003546240.012
spermatid differentiationGO:004851520.012
regulation of mechanoreceptor differentiationGO:004563110.012
system processGO:00030081850.012
regulation of oocyte developmentGO:006028130.012
spemann organizer formation at the embryonic shieldGO:006006320.012
thyroid gland developmentGO:0030878120.012
cell proliferation involved in heart morphogenesisGO:006132320.012
cell projection morphogenesisGO:00488582440.012
germ line stem cell maintenanceGO:003071820.012
regulation of retina development in camera type eyeGO:190286620.012
regulation of myelinationGO:003164110.012
cell migration involved in heart developmentGO:0060973220.011
microtubule organizing center organizationGO:003102310.011
foregut morphogenesisGO:000744040.011
muscle organ developmentGO:00075171010.011
olfactory bulb developmentGO:002177240.011
wnt signaling pathway involved in heart developmentGO:000330650.011
negative regulation of multi organism processGO:004390130.011
epiboly involved in gastrulation with mouth forming secondGO:0055113350.011
photoreceptor cell fate commitmentGO:004655210.011
regulation of organ morphogenesisGO:2000027350.011
positive regulation of protein metabolic processGO:0051247230.011
embryonic digestive tract developmentGO:004856640.011
homeostasis of number of cells within a tissueGO:004887340.011
cellular amide metabolic processGO:004360340.011
positive regulation of signalingGO:0023056560.011
regulation of membrane potentialGO:0042391230.011
protein targeting to nucleusGO:004474430.011
regulation of calcium ion transportGO:005192420.011
nucleocytoplasmic transportGO:000691340.011
brain morphogenesisGO:0048854180.011
positive regulation of neural precursor cell proliferationGO:200017910.011
lipid biosynthetic processGO:0008610220.011
stem cell developmentGO:0048864820.011
adult behaviorGO:003053420.011
single organism nuclear importGO:190259330.011
pronephric nephron tubule developmentGO:003902020.010
regulation of protein deacetylationGO:009031120.010
negative regulation of collateral sprouting of intact axon in response to injuryGO:004868520.010
establishment of protein localization to organelleGO:007259440.010
regulation of metal ion transportGO:001095940.010
regulation of histone deacetylationGO:003106320.010
spermatid developmentGO:000728620.010
organism emergence from protective structureGO:007168440.010
embryonic heart tube morphogenesisGO:00031431080.010
negative regulation of response to stimulusGO:00485851040.010
spinal cord radial glial cell differentiationGO:002153120.010
left right pattern formationGO:0060972190.010
multicellular organismal signalingGO:0035637220.010
liver developmentGO:0001889960.010
positive regulation of tyrosine phosphorylation of stat proteinGO:004253110.010
ectodermal placode developmentGO:0071696370.010

sesn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.041
cancerDOID:16200.041
disease of anatomical entityDOID:700.029
musculoskeletal system diseaseDOID:1700.029
connective tissue diseaseDOID:6500.024
dysostosisDOID:193400.023
bone development diseaseDOID:008000600.023
bone diseaseDOID:008000100.023
organ system cancerDOID:005068600.017