Danio rerio

0 known processes

ophn1

oligophrenin 1

(Aliases: zgc:92603)

ophn1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.085
agingGO:000756820.058
maintenance of locationGO:005123540.041
multicellular organism growthGO:003526440.040
signal transductionGO:00071654550.035
positive regulation of transportGO:005105020.035
lipid storageGO:001991510.034
positive regulation of catabolic processGO:000989640.034
meiotic nuclear divisionGO:000712640.033
autophagyGO:000691440.032
microtubule organizing center organizationGO:003102310.031
positive regulation of cellular component biogenesisGO:004408930.031
regulation of protein complex assemblyGO:004325430.031
ubiquitin dependent protein catabolic processGO:000651130.031
positive regulation of cellular catabolic processGO:003133130.030
regulation of multicellular organism growthGO:004001440.030
cellular response to external stimulusGO:007149620.030
establishment of protein localization to organelleGO:007259440.030
amine metabolic processGO:000930820.030
proteolysis involved in cellular protein catabolic processGO:005160330.029
cellular protein catabolic processGO:004425740.029
nuclear transportGO:005116940.029
regulation of cytokine productionGO:000181730.029
modification dependent protein catabolic processGO:001994130.028
endosomal transportGO:001619720.028
nitrogen compound metabolic processGO:00068073190.028
cellular macromolecule metabolic processGO:00442603910.028
protein importGO:001703830.028
cellular amine metabolic processGO:004410620.028
cellular nitrogen compound metabolic processGO:00346412900.028
heterocycle metabolic processGO:00464832900.027
gtp metabolic processGO:004603940.027
gtp catabolic processGO:000618420.026
stem cell maintenanceGO:001982740.026
mitochondrion organizationGO:000700540.026
regulation of protein transportGO:005122330.026
guanosine containing compound metabolic processGO:190106840.026
nucleobase containing compound metabolic processGO:00061392740.026
positive regulation of cell cycleGO:004578730.026
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.026
proteasomal protein catabolic processGO:001049820.025
organic cyclic compound metabolic processGO:19013603010.025
phagocytosisGO:000690930.025
modification dependent macromolecule catabolic processGO:004363230.025
stem cell divisionGO:001714510.025
guanosine containing compound catabolic processGO:190106920.025
nucleocytoplasmic transportGO:000691340.025
cellular response to starvationGO:000926710.025
regulation of metabolic processGO:00192223590.024
response to drugGO:004249330.024
single organism metabolic processGO:00447102170.024
cellular ketone metabolic processGO:0042180110.024
stem cell proliferationGO:007208940.024
regulation of protein catabolic processGO:004217610.024
negative regulation of biological processGO:00485193040.024
regulation of cellular amine metabolic processGO:003323800.024
organic substance biosynthetic processGO:19015762890.023
cytokinesisGO:000091030.023
organelle fusionGO:004828430.023
nucleic acid metabolic processGO:00903042440.023
cellular component disassemblyGO:002241110.023
regulation of bindingGO:005109830.023
biosynthetic processGO:00090582940.023
regulation of establishment of protein localizationGO:007020140.023
cell surface receptor signaling pathwayGO:00071663250.022
oxoacid metabolic processGO:0043436310.022
meiotic cell cycle processGO:190304630.022
regulation of cellular amino acid metabolic processGO:000652100.022
membrane fusionGO:006102520.022
cellular amino acid metabolic processGO:000652070.022
regulation of meiotic cell cycleGO:005144510.022
protein localization to nucleusGO:003450430.022
protein polymerizationGO:005125840.021
development of primary female sexual characteristicsGO:004654540.021
cellular response to extracellular stimulusGO:003166820.021
carboxylic acid metabolic processGO:0019752220.021
response to chemicalGO:00422213200.021
cellular response to nutrient levelsGO:003166920.021
organonitrogen compound metabolic processGO:1901564740.021
cellular biosynthetic processGO:00442492860.021
golgi vesicle transportGO:004819330.021
regulation of cellular ketone metabolic processGO:001056570.021
regulation of cell shapeGO:000836010.021
positive regulation of protein complex assemblyGO:003133420.021
regulation of protein modification by small protein conjugation or removalGO:190332030.021
regulation of cytoplasmic transportGO:190364940.021
rna localizationGO:000640340.020
neuroblast proliferationGO:000740520.020
cellular aromatic compound metabolic processGO:00067252950.020
rna metabolic processGO:00160702190.020
cellular response to molecule of bacterial originGO:007121930.020
small molecule metabolic processGO:0044281770.020
single organism nuclear importGO:190259330.020
regulation of cellular biosynthetic processGO:00313262450.020
nuclear importGO:005117030.020
regulation of signal transductionGO:00099662250.020
organic acid metabolic processGO:0006082310.020
gene expressionGO:00104672520.020
regulation of mrna processingGO:005068430.020
locomotor rhythmGO:004547530.020
regulation of cell activationGO:005086510.020
cognitionGO:005089010.019
regulation of protein ubiquitinationGO:003139630.019
embryo development ending in birth or egg hatchingGO:00097922710.019
peptidyl serine phosphorylationGO:001810510.019
tissue remodelingGO:004877140.019
single organism membrane fusionGO:004480120.019
ribonucleoside monophosphate catabolic processGO:000915840.019
regulation of alternative mrna splicing via spliceosomeGO:000038110.019
response to stressGO:00069502630.019
regulation of biological qualityGO:00650082630.019
regulation of cellular metabolic processGO:00313233200.019
cellular nitrogen compound biosynthetic processGO:00442712180.019
regulation of gtp catabolic processGO:003312420.019
positive regulation of cytokine productionGO:000181920.019
neuron differentiationGO:00301823530.019
regulation of nucleoside metabolic processGO:000911820.019
regulation of autophagyGO:001050630.018
protein acetylationGO:000647320.018
protein targeting to nucleusGO:004474430.018
peptidyl lysine acetylationGO:001839420.018
macroautophagyGO:001623610.018
protein metabolic processGO:00195381830.018
regulation of nucleocytoplasmic transportGO:004682220.018
nucleic acid templated transcriptionGO:00976591810.018
cellular respirationGO:004533330.018
internal protein amino acid acetylationGO:000647520.018
response to topologically incorrect proteinGO:003596620.018
adult behaviorGO:003053420.018
phagocytosis engulfmentGO:000691110.018
regulation of circadian rhythmGO:004275240.018
protein localization to plasma membraneGO:007265910.018
rna biosynthetic processGO:00327741810.018
regulation of metal ion transportGO:001095940.018
protein acylationGO:004354330.018
regulation of mrna splicing via spliceosomeGO:004802430.018
positive regulation of gtp catabolic processGO:003312610.018
internal peptidyl lysine acetylationGO:001839320.018
regulation of protein targetingGO:190353320.018
transcription dna templatedGO:00063511810.017
negative regulation of protein phosphorylationGO:000193340.017
cellular component movementGO:00069283350.017
regulation of rna metabolic processGO:00512522240.017
generation of neuronsGO:00486993850.017
positive regulation of biological processGO:00485182530.017
protein secretionGO:000930610.017
transportGO:00068102200.017
positive regulation of cellular amine metabolic processGO:003324000.017
cellular response to lipopolysaccharideGO:007122230.017
macromolecular complex disassemblyGO:003298410.017
protein import into nucleusGO:000660630.017
organic cyclic compound biosynthetic processGO:19013622230.017
central nervous system developmentGO:00074173870.017
regulation of organelle assemblyGO:190211540.017
regulation of macromolecule metabolic processGO:00602553170.017
cellular amide metabolic processGO:004360340.017
regulation of macromolecule biosynthetic processGO:00105562250.017
regulation of protein polymerizationGO:003227120.017
regulation of signalingGO:00230512350.017
regulation of nucleobase containing compound metabolic processGO:00192192500.017
protein dephosphorylationGO:000647030.017
regulation of cell communicationGO:00106462320.017
protein complex disassemblyGO:004324110.017
regulation of stem cell proliferationGO:007209120.017
female gonad developmentGO:000858540.016
regulation of intracellular protein transportGO:003315730.016
regulation of nitrogen compound metabolic processGO:00511712510.016
membrane invaginationGO:001032410.016
locomotionGO:00400113130.016
spermatid developmentGO:000728620.016
response to external stimulusGO:00096052640.016
regulation of response to stimulusGO:00485832690.016
single organism localizationGO:19025782250.016
positive regulation of stress activated mapk cascadeGO:003287430.016
response to uvGO:000941130.016
cellular response to biotic stimulusGO:007121630.016
regulation of cellular macromolecule biosynthetic processGO:20001122220.016
cellular component morphogenesisGO:00329893360.016
regulation of neural precursor cell proliferationGO:200017730.016
positive regulation of cell adhesionGO:004578510.016
cytoskeleton dependent cytokinesisGO:006164030.016
compound eye developmentGO:004874920.016
atp catabolic processGO:000620040.016
macromolecule biosynthetic processGO:00090592270.016
regulation of gtpase activityGO:004308720.016
extrinsic apoptotic signaling pathwayGO:009719130.016
actin polymerization or depolymerizationGO:000815420.016
regulation of primary metabolic processGO:00800903110.016
nucleobase containing compound biosynthetic processGO:00346542050.016
cellular carbohydrate metabolic processGO:004426240.016
protein polyubiquitinationGO:000020940.016
negative regulation of cellular processGO:00485232830.016
establishment of localizationGO:00512342440.016
positive regulation of secretionGO:005104710.015
regulation of nucleotide catabolic processGO:003081120.015
regulation of purine nucleotide catabolic processGO:003312120.015
double strand break repairGO:000630230.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
regulation of rna biosynthetic processGO:20011412130.015
carbohydrate homeostasisGO:003350010.015
positive regulation of secretion by cellGO:190353210.015
regulation of inflammatory responseGO:005072720.015
synaptic vesicle transportGO:004848910.015
synaptic vesicle localizationGO:009747910.015
cellular macromolecule biosynthetic processGO:00346452240.015
response to nutrientGO:000758430.015
positive regulation of cytoskeleton organizationGO:005149530.015
vasculature developmentGO:00019442780.015
regulation of jak stat cascadeGO:004642530.015
regulation of synaptic plasticityGO:004816710.015
regulation of gene expressionGO:00104682650.015
purine ribonucleoside monophosphate catabolic processGO:000916940.015
system processGO:00030081850.015
regulation of protein localization to nucleusGO:190018020.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
transmembrane transportGO:00550851200.015
regulation of protein import into nucleusGO:004230620.015
cell projection organizationGO:00300302840.015
regulation of biosynthetic processGO:00098892500.015
peptidyl serine modificationGO:001820920.015
aromatic compound biosynthetic processGO:00194382170.015
embryonic organ developmentGO:00485683810.015
establishment of protein localization to plasma membraneGO:009000210.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
homeostatic processGO:00425921420.015
positive regulation of immune effector processGO:000269930.015
tube morphogenesisGO:00352393490.015
response to alkaloidGO:004327920.015
regulation of nucleic acid templated transcriptionGO:19035062130.015
response to monosaccharideGO:003428430.014
cellular component biogenesisGO:00440851780.014
actin filament polymerizationGO:003004120.014
positive regulation of nucleotide catabolic processGO:003081310.014
positive regulation of cell activationGO:005086710.014
regulation of cellular protein catabolic processGO:190336210.014
female sex differentiationGO:004666040.014
sensory organ developmentGO:00074233930.014
regulation of cell projection assemblyGO:006049140.014
leukocyte proliferationGO:007066110.014
alternative mrna splicing via spliceosomeGO:000038010.014
positive regulation of map kinase activityGO:004340630.014
positive regulation of gtpase activityGO:004354710.014
chemosensory behaviorGO:000763510.014
cellular response to chemical stimulusGO:00708871570.014
single organism transportGO:00447652060.014
synaptic growth at neuromuscular junctionGO:005112420.014
single organism organelle organizationGO:19025891990.014
cell deathGO:00082191210.014
digestive system developmentGO:00551232890.014
neuron developmentGO:00486662620.014
mononuclear cell proliferationGO:003294310.014
glucose homeostasisGO:004259310.014
cellular response to topologically incorrect proteinGO:003596720.014
meiotic chromosome segregationGO:004513230.014
positive regulation of nucleoside metabolic processGO:004597910.014
cell migrationGO:00164772370.014
negative regulation of catabolic processGO:000989530.014
exocytosisGO:000688710.014
centrosome organizationGO:005129710.014
regulation of stem cell differentiationGO:200073640.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
regulation of synapse assemblyGO:005196330.013
regulation of reproductive processGO:200024140.013
purine nucleoside monophosphate catabolic processGO:000912840.013
vacuolar transportGO:000703420.013
response to hydrogen peroxideGO:004254230.013
cell motilityGO:00488702440.013
regulation of synapse organizationGO:005080730.013
single fertilizationGO:000733830.013
cell morphogenesisGO:00009022890.013
response to organic substanceGO:00100331530.013
centrosome cycleGO:000709810.013
spermatid differentiationGO:004851520.013
g1 s transition of mitotic cell cycleGO:000008210.013
regulation of organ growthGO:004662030.013
cell cycle g1 s phase transitionGO:004484310.013
symbiosis encompassing mutualism through parasitismGO:004440340.013
apoptotic processGO:00069151160.013
blood vessel developmentGO:00015682460.013
cell projection morphogenesisGO:00488582440.013
regulation of developmental processGO:00507932470.013
cellular response to light stimulusGO:007148240.013
cellular protein metabolic processGO:00442671290.013
lamellipodium assemblyGO:003003210.013
positive regulation of dna metabolic processGO:005105410.013
heterocycle biosynthetic processGO:00181302150.013
deathGO:00162651210.013
cell part morphogenesisGO:00329902460.013
cellular protein modification processGO:00064641000.013
camera type eye developmentGO:00430102220.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
cell substrate adhesionGO:003158940.013
eye developmentGO:00016542770.013
establishment of synaptic vesicle localizationGO:009748010.013
response to carbohydrateGO:000974330.013
cellular response to radiationGO:007147840.013
b cell activationGO:004211320.013
production of molecular mediator of immune responseGO:000244020.013
organelle organizationGO:00069962270.013
spindle assemblyGO:005122520.013
negative regulation of protein transportGO:005122430.013
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
regulation of programmed cell deathGO:00430671010.012
response to glucoseGO:000974930.012
morphogenesis of an epitheliumGO:00020093330.012
lipid homeostasisGO:005508830.012
peptide transportGO:001583310.012
immune system processGO:00023762410.012
regulation of transporter activityGO:003240920.012
macromolecule modificationGO:00434121110.012
regulation of transcription dna templatedGO:00063552130.012
alcohol biosynthetic processGO:004616520.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
negative regulation of sequestering of calcium ionGO:005128340.012
lymphocyte proliferationGO:004665110.012
nucleoside monophosphate catabolic processGO:000912540.012
antimicrobial humoral responseGO:001973020.012
negative regulation of protein kinase activityGO:000646940.012
sequestering of metal ionGO:005123830.012
regulation of multicellular organismal developmentGO:20000262230.012
positive regulation of cellular processGO:00485222010.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
negative regulation of cytokine productionGO:000181810.012
digestive tract developmentGO:00485652650.012
regulation of cell substrate adhesionGO:001081010.012
negative regulation of protein complex assemblyGO:003133310.012
response to abiotic stimulusGO:00096281220.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
erk1 and erk2 cascadeGO:007037140.012
regulation of apoptotic processGO:0042981980.012
interspecies interaction between organismsGO:004441940.012
regulation of carbohydrate metabolic processGO:000610940.012
brain developmentGO:00074202930.012
regionalizationGO:00030022740.012
lamellipodium organizationGO:009758110.012
cortical actin cytoskeleton organizationGO:003086610.012
negative regulation of intracellular transportGO:003238730.011
cell matrix adhesionGO:000716040.011
embryonic organ morphogenesisGO:00485622740.011
growthGO:00400071740.011
endosome organizationGO:000703220.011
localization of cellGO:00516742440.011
blood vessel morphogenesisGO:00485142160.011
positive regulation of translationGO:004572710.011
i kappab kinase nf kappab signalingGO:000724940.011
translational initiationGO:000641330.011
wnt signaling pathwayGO:0016055800.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
regulation of erk1 and erk2 cascadeGO:007037240.011
rna transportGO:005065820.011
somatic stem cell maintenanceGO:003501910.011
neuron neuron synaptic transmissionGO:000727010.011
regulation of blood pressureGO:000821710.011
cellular component assemblyGO:00226071700.011
post embryonic organ developmentGO:004856940.011
regulation of cell deathGO:00109411030.011
secondary metabolic processGO:001974830.011
negative regulation of mapk cascadeGO:004340940.011
regulation of multicellular organismal processGO:00512392770.011
response to nicotineGO:003509420.011
entrainment of circadian clockGO:000964920.011
negative regulation of kinase activityGO:003367340.011
digestive tract morphogenesisGO:00485462310.011
negative regulation of cellular catabolic processGO:003133030.011
chordate embryonic developmentGO:00430092710.011
positive regulation of jnk cascadeGO:004633030.011
protein modification processGO:00362111000.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
neuromuscular synaptic transmissionGO:000727420.011
activation of mapk activityGO:000018730.011
regulation of protein complex disassemblyGO:004324410.011
mitotic cytokinesisGO:000028130.011
positive regulation of canonical wnt signaling pathwayGO:009026340.011
lateral inhibitionGO:004633110.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
head developmentGO:00603223030.011
nuclear exportGO:005116810.011
protein homooligomerizationGO:005126030.011
sequestering of calcium ionGO:005120830.011
programmed cell deathGO:00125011190.011
negative regulation of defense responseGO:003134820.011
nucleobase containing compound transportGO:001593120.011
negative regulation of multi organism processGO:004390130.011
regulation of wnt signaling pathwayGO:0030111530.011
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.011
cellular transition metal ion homeostasisGO:004691630.011
mitochondrial transportGO:000683920.010
intracellular signal transductionGO:0035556850.010
cytokinetic processGO:003250620.010
response to woundingGO:00096111160.010
positive regulation of protein polymerizationGO:003227320.010
positive regulation of leukocyte differentiationGO:190210710.010
muscle structure developmentGO:00610611960.010
developmental growthGO:00485891660.010
liver developmentGO:0001889960.010
regulation of transmembrane transporter activityGO:002289820.010
regulation of response to biotic stimulusGO:000283120.010
carbohydrate biosynthetic processGO:001605110.010
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.010
response to hexoseGO:000974630.010
regulation of receptor mediated endocytosisGO:004825940.010
hormone secretionGO:004687920.010
mitotic dna integrity checkpointGO:004477440.010
positive regulation of myeloid cell differentiationGO:004563920.010
regulation of muscle contractionGO:000693730.010
regulation of chromosome segregationGO:005198310.010
immune system developmentGO:00025201910.010
tube closureGO:006060610.010
axon developmentGO:00615641660.010
negative regulation of response to stimulusGO:00485851040.010
sex determinationGO:000753010.010
cellular monovalent inorganic cation homeostasisGO:003000420.010
negative regulation of protein localization to nucleusGO:190018120.010
dna templated transcription elongationGO:000635430.010
multi organism processGO:00517041340.010
positive regulation of notch signaling pathwayGO:004574730.010
protein targeting to membraneGO:000661210.010
cell substrate junction assemblyGO:000704420.010
negative regulation of signalingGO:0023057960.010
post golgi vesicle mediated transportGO:000689210.010

ophn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
nervous system diseaseDOID:86300.024
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
disease of metabolismDOID:001466700.014
musculoskeletal system diseaseDOID:1700.014
eye and adnexa diseaseDOID:149200.012
sensory system diseaseDOID:005015500.012
inherited metabolic disorderDOID:65500.011
organ system cancerDOID:005068600.011