Danio rerio

0 known processes

jak2b

Janus kinase 2b

(Aliases: JAK2bCA,jak2)

jak2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.116
protein localization to nucleusGO:003450430.087
nucleocytoplasmic transportGO:000691340.084
larval developmentGO:000216420.081
cellular macromolecule metabolic processGO:00442603910.077
cellular biosynthetic processGO:00442492860.076
single organism localizationGO:19025782250.075
nitrogen compound metabolic processGO:00068073190.074
digestive tract developmentGO:00485652650.071
modification dependent macromolecule catabolic processGO:004363230.071
nuclear transportGO:005116940.070
establishment of localizationGO:00512342440.069
embryonic organ developmentGO:00485683810.068
sensory organ developmentGO:00074233930.065
single organism transportGO:00447652060.064
single organism nuclear importGO:190259330.064
protein targeting to nucleusGO:004474430.064
eye developmentGO:00016542770.062
regulation of protein import into nucleusGO:004230620.059
generation of neuronsGO:00486993850.058
negative regulation of protein transportGO:005122430.058
establishment of protein localization to organelleGO:007259440.057
regulation of nucleocytoplasmic transportGO:004682220.057
regulation of protein targetingGO:190353320.056
locomotionGO:00400113130.056
cognitionGO:005089010.055
regulation of macromolecule metabolic processGO:00602553170.054
response to chemicalGO:00422213200.054
response to external stimulusGO:00096052640.052
nuclear importGO:005117030.052
regulation of establishment of protein localizationGO:007020140.050
protein import into nucleusGO:000660630.049
regulation of cellular metabolic processGO:00313233200.049
protein importGO:001703830.048
ubiquitin dependent protein catabolic processGO:000651130.048
regulation of nitrogen compound metabolic processGO:00511712510.048
organic cyclic compound metabolic processGO:19013603010.047
embryo development ending in birth or egg hatchingGO:00097922710.046
positive regulation of transportGO:005105020.046
positive regulation of cell cycleGO:004578730.046
cellular protein catabolic processGO:004425740.045
modification dependent protein catabolic processGO:001994130.044
adult behaviorGO:003053420.044
head developmentGO:00603223030.044
cell morphogenesisGO:00009022890.043
central nervous system developmentGO:00074173870.043
neuron developmentGO:00486662620.043
heterocycle metabolic processGO:00464832900.042
negative regulation of intracellular protein transportGO:009031730.042
cellular modified amino acid metabolic processGO:000657530.042
hormone transportGO:000991420.041
regulation of protein localization to nucleusGO:190018020.040
regulation of cellular macromolecule biosynthetic processGO:20001122220.040
camera type eye developmentGO:00430102220.039
positive regulation of cellular catabolic processGO:003133130.039
negative regulation of cytoplasmic transportGO:190365020.039
rna metabolic processGO:00160702190.039
neuron differentiationGO:00301823530.039
dicarboxylic acid transportGO:000683510.038
regulation of cytoplasmic transportGO:190364940.038
proteolysis involved in cellular protein catabolic processGO:005160330.038
system processGO:00030081850.038
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.038
regulation of intracellular protein transportGO:003315730.037
regulation of signalingGO:00230512350.037
protein metabolic processGO:00195381830.037
heart developmentGO:00075073130.037
autophagyGO:000691440.036
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.036
chordate embryonic developmentGO:00430092710.036
maintenance of locationGO:005123540.036
heterocycle biosynthetic processGO:00181302150.036
digestive system developmentGO:00551232890.036
single organism metabolic processGO:00447102170.035
rna localizationGO:000640340.035
vasculature developmentGO:00019442780.035
stem cell proliferationGO:007208940.035
peptide transportGO:001583310.035
multicellular organism growthGO:003526440.035
organic cyclic compound biosynthetic processGO:19013622230.035
regulation of protein catabolic processGO:004217610.035
phagocytosisGO:000690930.034
synaptic growth at neuromuscular junctionGO:005112420.034
regulation of synapse assemblyGO:005196330.034
regulation of multicellular organismal processGO:00512392770.034
organelle organizationGO:00069962270.034
cellular component morphogenesisGO:00329893360.034
neuroblast proliferationGO:000740520.033
protein polymerizationGO:005125840.033
positive regulation of biological processGO:00485182530.033
cellular nitrogen compound metabolic processGO:00346412900.033
regulation of nucleic acid templated transcriptionGO:19035062130.033
cell morphogenesis involved in differentiationGO:00009041950.033
signal transductionGO:00071654550.033
regulation of circadian rhythmGO:004275240.033
positive regulation of catabolic processGO:000989640.033
regulation of protein transportGO:005122330.032
morphogenesis of an epitheliumGO:00020093330.032
cellular response to starvationGO:000926710.032
regulation of multicellular organism growthGO:004001440.032
dicarboxylic acid metabolic processGO:004364810.031
organic substance biosynthetic processGO:19015762890.031
regulation of synaptic growth at neuromuscular junctionGO:000858210.031
single organism organelle organizationGO:19025891990.031
apoptotic processGO:00069151160.030
cellular response to nutrient levelsGO:003166920.030
biosynthetic processGO:00090582940.030
regulation of synapse organizationGO:005080730.030
negative regulation of cellular processGO:00485232830.030
regulation of synaptic plasticityGO:004816710.030
organelle assemblyGO:00709251100.030
regulation of cell communicationGO:00106462320.029
cell surface receptor signaling pathwayGO:00071663250.029
guanosine containing compound catabolic processGO:190106920.029
negative regulation of protein complex assemblyGO:003133310.029
cell projection morphogenesisGO:00488582440.029
cellular nitrogen compound biosynthetic processGO:00442712180.029
transportGO:00068102200.029
negative regulation of nucleocytoplasmic transportGO:004682320.028
cellular aromatic compound metabolic processGO:00067252950.028
nucleic acid metabolic processGO:00903042440.028
regulation of transcription dna templatedGO:00063552130.028
cellular response to external stimulusGO:007149620.028
cell projection organizationGO:00300302840.028
cellular component disassemblyGO:002241110.027
nucleobase containing compound metabolic processGO:00061392740.027
lipid storageGO:001991510.027
locomotor rhythmGO:004547530.027
response to glucoseGO:000974930.027
brain developmentGO:00074202930.027
cellular response to extracellular stimulusGO:003166820.027
macromolecule biosynthetic processGO:00090592270.026
homeostatic processGO:00425921420.026
negative regulation of synapse assemblyGO:005196420.026
regulation of developmental processGO:00507932470.026
regulation of autophagyGO:001050630.026
muscle structure developmentGO:00610611960.026
guanosine containing compound metabolic processGO:190106840.026
response to nutrientGO:000758430.026
regulation of reproductive processGO:200024140.026
cellular protein metabolic processGO:00442671290.026
cell migrationGO:00164772370.026
proteasomal protein catabolic processGO:001049820.026
neurotransmitter transportGO:000683620.026
regulation of protein complex assemblyGO:004325430.026
response to hexoseGO:000974630.025
negative regulation of protein phosphorylationGO:000193340.025
determination of left right symmetryGO:00073681790.025
regulation of biosynthetic processGO:00098892500.025
cellular localizationGO:0051641970.025
cellular component assemblyGO:00226071700.025
negative regulation of protein import into nucleusGO:004230820.025
neurotransmitter secretionGO:000726920.025
stem cell divisionGO:001714510.025
transcription dna templatedGO:00063511810.025
regulation of blood vessel sizeGO:005088020.025
response to stressGO:00069502630.025
cell part morphogenesisGO:00329902460.024
negative regulation of biological processGO:00485193040.024
extrinsic apoptotic signaling pathwayGO:009719130.024
regulation of biological qualityGO:00650082630.024
nucleic acid templated transcriptionGO:00976591810.024
blood vessel morphogenesisGO:00485142160.024
alpha amino acid metabolic processGO:190160530.024
glucose importGO:004632320.024
regulation of purine nucleotide catabolic processGO:003312120.023
mitochondrion organizationGO:000700540.023
meiotic nuclear divisionGO:000712640.023
gene expressionGO:00104672520.023
positive regulation of blood circulationGO:190352420.023
cytoskeleton dependent cytokinesisGO:006164030.023
response to carbohydrateGO:000974330.023
regulation of rna metabolic processGO:00512522240.023
tube morphogenesisGO:00352393490.023
protein complex disassemblyGO:004324110.023
regulation of signal transductionGO:00099662250.023
gtp metabolic processGO:004603940.023
cell morphogenesis involved in neuron differentiationGO:00486671630.023
regulation of bindingGO:005109830.023
actin polymerization or depolymerizationGO:000815420.023
growthGO:00400071740.023
regulation of organ growthGO:004662030.023
enzyme linked receptor protein signaling pathwayGO:00071671060.023
retina development in camera type eyeGO:00600411460.023
protein modification processGO:00362111000.022
response to drugGO:004249330.022
regulation of nucleotide catabolic processGO:003081120.022
regulation of response to stimulusGO:00485832690.022
nucleic acid transportGO:005065720.022
cytoplasm organizationGO:000702840.022
cellular component biogenesisGO:00440851780.022
cellular amine metabolic processGO:004410620.022
gtp catabolic processGO:000618420.022
cell agingGO:000756920.022
liver developmentGO:0001889960.022
hormone secretionGO:004687920.022
programmed cell deathGO:00125011190.022
rna biosynthetic processGO:00327741810.022
deathGO:00162651210.022
negative regulation of response to stimulusGO:00485851040.022
anterior posterior pattern specificationGO:00099521520.021
organonitrogen compound metabolic processGO:1901564740.021
determination of bilateral symmetryGO:00098552040.021
regulation of stem cell proliferationGO:007209120.021
neuron projection morphogenesisGO:00488121610.021
macromolecular complex disassemblyGO:003298410.021
regulation of wound healingGO:006104120.021
specification of symmetryGO:00097992040.021
negative regulation of intracellular transportGO:003238730.021
regulation of macromolecule biosynthetic processGO:00105562250.021
cellular amino acid metabolic processGO:000652070.021
pancreas developmentGO:0031016840.021
response to monosaccharideGO:003428430.021
negative regulation of cellular catabolic processGO:003133030.021
centrosome organizationGO:005129710.021
regulation of glucose importGO:004632410.021
regulation of rna biosynthetic processGO:20011412130.021
cellular response to chemical stimulusGO:00708871570.021
endosomal transportGO:001619720.021
negative regulation of protein localization to nucleusGO:190018120.021
lateral inhibitionGO:004633110.020
cellular response to organic substanceGO:00713101050.020
amine metabolic processGO:000930820.020
sleepGO:003043110.020
protein polyubiquitinationGO:000020940.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
compound eye developmentGO:004874920.020
axon developmentGO:00615641660.020
aromatic compound biosynthetic processGO:00194382170.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.019
cell substrate adhesionGO:003158940.019
stem cell maintenanceGO:001982740.019
synaptic vesicle transportGO:004848910.019
regulation of gene expressionGO:00104682650.019
response to corticosteroidGO:003196010.019
multi organism processGO:00517041340.019
regulation of primary metabolic processGO:00800903110.019
membrane fusionGO:006102520.019
negative regulation of catabolic processGO:000989530.019
regulation of tube sizeGO:003515020.019
circulatory system processGO:0003013870.019
regulation of nucleoside metabolic processGO:000911820.019
lipid catabolic processGO:001604240.019
regulation of cellular amino acid metabolic processGO:000652100.019
digestive tract morphogenesisGO:00485462310.018
regulation of glucose transportGO:001082710.018
regulation of cellular amine metabolic processGO:003323800.018
tissue remodelingGO:004877140.018
regulation of nucleobase containing compound metabolic processGO:00192192500.018
regulation of protein ubiquitinationGO:003139630.018
hepaticobiliary system developmentGO:0061008980.018
regulation of carbohydrate metabolic processGO:000610940.018
response to alkaloidGO:004327920.018
macroautophagyGO:001623610.018
amino acid transportGO:000686520.018
regulation of cellular biosynthetic processGO:00313262450.018
phosphate containing compound metabolic processGO:00067961080.018
xenobiotic metabolic processGO:000680540.018
female gonad developmentGO:000858540.018
regulation of protein polymerizationGO:003227120.017
regulation of response to nutrient levelsGO:003210710.017
regulation of cell differentiationGO:00455951420.017
regulation of metabolic processGO:00192223590.017
zymogen activationGO:003163830.017
cartilage developmentGO:0051216960.017
response to glucocorticoidGO:005138410.017
segmentationGO:0035282970.017
regulation of programmed cell deathGO:00430671010.017
regulation of jak stat cascadeGO:004642530.017
cellular component movementGO:00069283350.017
regulation of cell deathGO:00109411030.017
regulation of dendrite developmentGO:005077330.017
small molecule metabolic processGO:0044281770.017
sensory organ morphogenesisGO:00905962000.017
regulation of dendrite morphogenesisGO:004881430.017
golgi vesicle transportGO:004819330.017
nucleobase containing compound biosynthetic processGO:00346542050.017
positive regulation of metabolic processGO:00098931080.017
negative regulation of small gtpase mediated signal transductionGO:005105810.017
organic acid metabolic processGO:0006082310.017
actin filament polymerizationGO:003004120.017
regulation of cell developmentGO:00602841000.017
negative regulation of map kinase activityGO:004340720.016
behaviorGO:0007610740.016
positive regulation of cell divisionGO:005178120.016
regulation of response to extracellular stimulusGO:003210410.016
phosphorus metabolic processGO:00067931090.016
endocrine processGO:005088620.016
myeloid cell differentiationGO:0030099860.016
spermatid developmentGO:000728620.016
negative regulation of mapk cascadeGO:004340940.016
regulation of transcription from rna polymerase ii promoterGO:00063571140.016
regulation of embryonic developmentGO:0045995470.016
interspecies interaction between organismsGO:004441940.016
regulation of cell activationGO:005086510.016
response to vitaminGO:003327330.016
oocyte anterior posterior axis specificationGO:000731440.016
ribonucleoside monophosphate catabolic processGO:000915840.016
mesoderm developmentGO:0007498880.016
nuclear exportGO:005116810.016
peptidyl threonine phosphorylationGO:001810710.016
centrosome cycleGO:000709810.016
forebrain developmentGO:0030900960.016
embryonic organ morphogenesisGO:00485622740.016
glial cell proliferationGO:001400940.016
mesenchyme developmentGO:00604851270.016
cortical cytoskeleton organizationGO:003086510.016
cytokinesisGO:000091030.016
negative regulation of gene expressionGO:0010629650.016
nuclear migrationGO:000709730.016
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.015
response to organic substanceGO:00100331530.015
regulation of hormone secretionGO:004688320.015
positive regulation of dna metabolic processGO:005105410.015
negative regulation of ras protein signal transductionGO:004658010.015
negative regulation of cellular metabolic processGO:0031324770.015
immune system processGO:00023762410.015
Zebrafish
regulation of cellular carbohydrate metabolic processGO:001067540.015
symbiosis encompassing mutualism through parasitismGO:004440340.015
post embryonic organ developmentGO:004856940.015
epithelial tube morphogenesisGO:00605621480.015
negative regulation of kinase activityGO:003367340.015
blood circulationGO:0008015870.015
cellular lipid catabolic processGO:004424230.015
regulation of localizationGO:00328791040.015
positive regulation of stress activated mapk cascadeGO:003287430.015
negative regulation of reproductive processGO:200024230.015
glucose homeostasisGO:004259310.015
locomotory behaviorGO:0007626340.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
negative regulation of protein serine threonine kinase activityGO:007190120.015
establishment of synaptic vesicle localizationGO:009748010.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015
positive regulation of nucleotide catabolic processGO:003081310.015
negative regulation of protein kinase activityGO:000646940.015
meiotic cell cycle processGO:190304630.015
regulation of cytokine productionGO:000181730.015
determination of heart left right asymmetryGO:00613711170.015
regulation of endocrine processGO:004406020.015
negative regulation of programmed cell deathGO:0043069580.015
cell motilityGO:00488702440.015
carbohydrate biosynthetic processGO:001605110.015
gland developmentGO:00487321430.015
protein dephosphorylationGO:000647030.015
organelle localizationGO:0051640490.015
gastrulationGO:00073692080.015
cellular macromolecule biosynthetic processGO:00346452240.014
single organism membrane fusionGO:004480120.014
negative regulation of metabolic processGO:0009892860.014
apoptotic process involved in developmentGO:190274220.014
heart contractionGO:0060047710.014
regulation of myotube differentiationGO:001083020.014
regulation of multicellular organismal developmentGO:20000262230.014
monoamine transportGO:001584410.014
positive regulation of glucose importGO:004632610.014
adherens junction organizationGO:003433240.014
positive regulation of cellular component biogenesisGO:004408930.014
intracellular mrna localizationGO:000829810.014
spermatid differentiationGO:004851520.014
positive regulation of canonical wnt signaling pathwayGO:009026340.014
cell deathGO:00082191210.014
neural tube developmentGO:0021915620.014
cellular response to decreased oxygen levelsGO:003629410.014
protein localization to plasma membraneGO:007265910.014
cortical actin cytoskeleton organizationGO:003086610.014
positive regulation of gtpase activityGO:004354710.014
mechanosensory behaviorGO:000763820.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
nucleoside monophosphate catabolic processGO:000912540.014
localization of cellGO:00516742440.014
purine nucleoside monophosphate catabolic processGO:000912840.014
angiogenesisGO:00015251580.014
carboxylic acid metabolic processGO:0019752220.014
synaptic vesicle localizationGO:009747910.014
cellular ketone metabolic processGO:0042180110.014
organelle fusionGO:004828430.014
heart morphogenesisGO:00030071560.014
regulation of stem cell differentiationGO:200073640.014
regulation of inflammatory responseGO:005072720.014
peptidyl lysine acetylationGO:001839420.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
regulation of gtpase activityGO:004308720.014
response to external biotic stimulusGO:0043207970.013
regulation of blood pressureGO:000821710.013
internal protein amino acid acetylationGO:000647520.013
positive regulation of cell adhesionGO:004578510.013
positive regulation of map kinase activityGO:004340630.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
negative regulation of signal transductionGO:0009968940.013
rna transportGO:005065820.013
internal peptidyl lysine acetylationGO:001839320.013
chemical homeostasisGO:0048878490.013
carbohydrate homeostasisGO:003350010.013
steroid hormone secretionGO:003592910.013
striated muscle cell developmentGO:00550021080.013
regulation of epithelial cell proliferationGO:005067830.013
endocrine hormone secretionGO:006098620.013
positive regulation of protein kinase b signalingGO:005189710.013
regulation of apoptotic processGO:0042981980.013
somatic muscle developmentGO:000752540.013
establishment of rna localizationGO:005123630.013
calcium ion transport into cytosolGO:006040230.013
protein acetylationGO:000647320.013
microtubule cytoskeleton organization involved in mitosisGO:190285010.013
regulation of gtp catabolic processGO:003312420.013
skeletal system developmentGO:00015011810.013
regulation of metal ion transportGO:001095940.013
muscle cell developmentGO:00550011150.013
muscle fiber developmentGO:0048747520.013
microtubule polymerization or depolymerizationGO:003110930.013
chemosensory behaviorGO:000763510.013
pole plasm assemblyGO:000731540.013
regulation of protein bindingGO:004339330.013
macromolecule localizationGO:0033036540.013
cellular carbohydrate metabolic processGO:004426240.013
blood vessel developmentGO:00015682460.013
transcription from rna polymerase ii promoterGO:0006366800.013
circadian sleep wake cycle processGO:002241020.013
maternal determination of anterior posterior axis embryoGO:000835840.013
neuron projection guidanceGO:0097485860.013
neurological system processGO:0050877620.013
cellular protein modification processGO:00064641000.013
muscle organ developmentGO:00075171010.013
axonogenesisGO:00074091520.013
atp catabolic processGO:000620040.013
tube closureGO:006060610.013
erythrocyte homeostasisGO:0034101550.013
regulation of cell projection assemblyGO:006049140.013
immune system developmentGO:00025201910.013
Zebrafish
meiotic chromosome segregationGO:004513230.013
erk1 and erk2 cascadeGO:007037140.013
neuron projection developmentGO:00311751800.012
regulation of neurotransmitter transportGO:005158810.012
positive regulation of striated muscle cell differentiationGO:005115510.012
regulation of neurogenesisGO:0050767870.012
multicellular organismal response to stressGO:003355520.012
embryonic cranial skeleton morphogenesisGO:0048701900.012
sensory perception of chemical stimulusGO:000760630.012
olfactory lobe developmentGO:002198840.012
protein depolymerizationGO:005126110.012
regulation of cellular ketone metabolic processGO:001056570.012
cellular response to hypoxiaGO:007145610.012
negative regulation of signalingGO:0023057960.012
regulation of systemic arterial blood pressureGO:000307310.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
reactive nitrogen species metabolic processGO:200105700.012
macromolecule modificationGO:00434121110.012
regionalizationGO:00030022740.012
carbon dioxide transportGO:001567030.012
heart processGO:0003015710.012
regulation of nervous system developmentGO:0051960900.012
positive regulation of neuron deathGO:190121610.012
positive regulation of gliogenesisGO:001401520.012
phototransductionGO:000760220.012
sensory perception of smellGO:000760820.012
regulation of cell shapeGO:000836010.012
erythrocyte differentiationGO:0030218540.012
iron ion homeostasisGO:005507240.012
response to hydrogen peroxideGO:004254230.012
hydrogen peroxide metabolic processGO:004274320.012
urogenital system developmentGO:0001655970.012
cellular response to hormone stimulusGO:0032870390.012
positive regulation of stem cell proliferationGO:200064810.012
medulla oblongata developmentGO:002155040.012
positive regulation of cellular amine metabolic processGO:003324000.012
axon guidanceGO:0007411860.012
vacuolar transportGO:000703420.012
multicellular organismal metabolic processGO:004423620.012
regulation of protein depolymerizationGO:190187910.012
actin filament based movementGO:003004810.012
regulation of response to cytokine stimulusGO:006075930.012
primary neural tube formationGO:001402010.012
membrane invaginationGO:001032410.012
neuromuscular process controlling balanceGO:005088530.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
negative regulation of macromolecule metabolic processGO:0010605760.011
positive regulation of muscle organ developmentGO:004863610.011
positive regulation of protein complex assemblyGO:003133420.011
cation transportGO:0006812810.011
peptidyl threonine modificationGO:001821010.011
negative regulation of cell deathGO:0060548600.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.011
regulation of anatomical structure morphogenesisGO:00226031300.011
hemopoiesisGO:00300971830.011
Zebrafish
cellular component assembly involved in morphogenesisGO:00109271070.011
rna 3 end processingGO:003112320.011
negative regulation of cell communicationGO:0010648960.011
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.011

jak2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
organ system cancerDOID:005068600.023
disease of cellular proliferationDOID:1456600.023
cancerDOID:16200.023
nervous system diseaseDOID:86300.017
disease of metabolismDOID:001466700.014
inherited metabolic disorderDOID:65500.013
musculoskeletal system diseaseDOID:1700.012