Danio rerio

0 known processes

cflar

CASP8 and FADD-like apoptosis regulator

(Aliases: Clarp1)

cflar biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of metabolic processGO:00192223590.115
single organism transportGO:00447652060.107
multi organism cellular processGO:004476420.106
positive regulation of biological processGO:00485182530.092
larval developmentGO:000216420.088
single organism localizationGO:19025782250.087
protein localization to nucleusGO:003450430.087
regulation of establishment of protein localizationGO:007020140.084
regulation of extrinsic apoptotic signaling pathwayGO:200123630.083
extrinsic apoptotic signaling pathwayGO:009719130.082
regulation of cytokine productionGO:000181730.082
regulation of protein localization to nucleusGO:190018020.082
nuclear transportGO:005116940.078
hematopoietic or lymphoid organ developmentGO:00485341910.077
negative regulation of protein phosphorylationGO:000193340.076
cellular macromolecule metabolic processGO:00442603910.074
establishment of protein localization to organelleGO:007259440.073
cellular nitrogen compound metabolic processGO:00346412900.073
ubiquitin dependent protein catabolic processGO:000651130.073
regulation of macromolecule metabolic processGO:00602553170.073
chordate embryonic developmentGO:00430092710.071
negative regulation of cellular processGO:00485232830.068
regulation of biosynthetic processGO:00098892500.067
gland developmentGO:00487321430.066
modulation by virus of host morphology or physiologyGO:001904810.066
response to biotic stimulusGO:0009607970.065
protein import into nucleusGO:000660630.065
regulation of protein import into nucleusGO:004230620.065
viral processGO:001603210.064
single organism nuclear importGO:190259330.064
nuclear importGO:005117030.063
regulation of glucose transportGO:001082710.063
regulation of biological qualityGO:00650082630.059
establishment of localizationGO:00512342440.058
negative regulation of biological processGO:00485193040.058
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.058
positive regulation of transportGO:005105020.058
interaction with hostGO:005170140.057
organic cyclic compound metabolic processGO:19013603010.057
protein targeting to nucleusGO:004474430.057
nucleocytoplasmic transportGO:000691340.056
regulation of intracellular protein transportGO:003315730.056
rna biosynthetic processGO:00327741810.056
protein importGO:001703830.055
cellular aromatic compound metabolic processGO:00067252950.055
embryo development ending in birth or egg hatchingGO:00097922710.054
biosynthetic processGO:00090582940.053
regulation of protein targetingGO:190353320.053
response to abiotic stimulusGO:00096281220.053
immune system processGO:00023762410.052
regulation of cell activationGO:005086510.052
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.051
b cell activationGO:004211320.051
cellular ketone metabolic processGO:0042180110.050
regulation of cysteine type endopeptidase activityGO:2000116210.050
regulation of protein transportGO:005122330.050
immune system developmentGO:00025201910.049
response to stressGO:00069502630.048
response to external stimulusGO:00096052640.048
stem cell maintenanceGO:001982740.048
heterocycle metabolic processGO:00464832900.048
organic substance biosynthetic processGO:19015762890.048
regulation of protein complex assemblyGO:004325430.047
regulation of cytoplasmic transportGO:190364940.047
digestive system developmentGO:00551232890.047
cellular protein catabolic processGO:004425740.047
regulation of primary metabolic processGO:00800903110.046
regulation of nucleocytoplasmic transportGO:004682220.046
negative regulation of protein localization to nucleusGO:190018120.046
glucose importGO:004632320.044
mitochondrion organizationGO:000700540.044
leukocyte proliferationGO:007066110.044
autophagyGO:000691440.044
transportGO:00068102200.044
regulation of cellular metabolic processGO:00313233200.043
phagocytosisGO:000690930.042
heterocycle biosynthetic processGO:00181302150.042
gene expressionGO:00104672520.042
cellular component assemblyGO:00226071700.041
hemopoiesisGO:00300971830.041
regulation of macromolecule biosynthetic processGO:00105562250.041
centrosome organizationGO:005129710.040
multicellular organism growthGO:003526440.040
gtp metabolic processGO:004603940.040
regulation of localizationGO:00328791040.040
regulation of stem cell differentiationGO:200073640.040
establishment of protein localization to plasma membraneGO:009000210.040
proteasomal protein catabolic processGO:001049820.038
cellular biosynthetic processGO:00442492860.038
agingGO:000756820.038
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.038
regulation of response to stimulusGO:00485832690.037
cellular component morphogenesisGO:00329893360.037
nucleobase containing compound metabolic processGO:00061392740.037
positive regulation of cellular processGO:00485222010.037
organic acid metabolic processGO:0006082310.036
response to other organismGO:0051707970.036
zymogen activationGO:003163830.036
amine metabolic processGO:000930820.036
regulation of reactive oxygen species metabolic processGO:200037720.035
modification dependent protein catabolic processGO:001994130.035
modification dependent macromolecule catabolic processGO:004363230.035
regulation of multicellular organism growthGO:004001440.035
neuron developmentGO:00486662620.035
small molecule metabolic processGO:0044281770.035
positive regulation of protein complex assemblyGO:003133420.035
convergent extensionGO:00600261180.034
nucleic acid templated transcriptionGO:00976591810.034
centrosome cycleGO:000709810.034
nucleobase containing compound biosynthetic processGO:00346542050.034
positive regulation of cell activationGO:005086710.034
positive regulation of macromolecule metabolic processGO:0010604930.034
positive regulation of cytokine productionGO:000181920.034
response to organic substanceGO:00100331530.034
neuron differentiationGO:00301823530.033
regulation of cellular macromolecule biosynthetic processGO:20001122220.033
positive regulation of cell killingGO:003134320.033
membrane fusionGO:006102520.033
response to chemicalGO:00422213200.032
proteolysis involved in cellular protein catabolic processGO:005160330.032
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.032
nitrogen compound metabolic processGO:00068073190.032
liver developmentGO:0001889960.032
protein localization to plasma membraneGO:007265910.032
cell projection morphogenesisGO:00488582440.031
protein acetylationGO:000647320.031
maintenance of locationGO:005123540.031
generation of neuronsGO:00486993850.031
regulation of hormone secretionGO:004688320.031
peptide transportGO:001583310.031
regulation of peptidase activityGO:0052547230.031
cell surface receptor signaling pathwayGO:00071663250.031
cell projection organizationGO:00300302840.030
locomotor rhythmGO:004547530.030
cellular macromolecule biosynthetic processGO:00346452240.030
macromolecule biosynthetic processGO:00090592270.030
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.030
single organism membrane fusionGO:004480120.030
regulation of gene expressionGO:00104682650.030
cellular amine metabolic processGO:004410620.030
organonitrogen compound metabolic processGO:1901564740.030
mononuclear cell proliferationGO:003294310.030
interspecies interaction between organismsGO:004441940.030
positive regulation of cellular component biogenesisGO:004408930.030
regulation of developmental processGO:00507932470.030
internal peptidyl lysine acetylationGO:001839320.030
guanosine containing compound catabolic processGO:190106920.029
oxoacid metabolic processGO:0043436310.029
regulation of transcription from rna polymerase ii promoterGO:00063571140.029
regulation of apoptotic processGO:0042981980.029
regulation of synapse organizationGO:005080730.029
regulation of cellular amine metabolic processGO:003323800.029
regulation of rna metabolic processGO:00512522240.029
single organism metabolic processGO:00447102170.028
protein metabolic processGO:00195381830.028
muscle structure developmentGO:00610611960.028
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.028
aromatic compound biosynthetic processGO:00194382170.028
cellular response to external stimulusGO:007149620.028
regulation of inflammatory responseGO:005072720.027
stem cell divisionGO:001714510.027
regulation of skeletal muscle fiber developmentGO:004874220.027
regulation of cell deathGO:00109411030.027
somite developmentGO:0061053960.027
positive regulation of biosynthetic processGO:0009891680.027
response to glucocorticoidGO:005138410.027
regulation of cellular amino acid metabolic processGO:000652100.027
production of molecular mediator of immune responseGO:000244020.027
purine nucleoside monophosphate catabolic processGO:000912840.026
meiotic nuclear divisionGO:000712640.026
modification by symbiont of host morphology or physiologyGO:004400340.026
rna metabolic processGO:00160702190.026
regulation of cellular ketone metabolic processGO:001056570.026
somitogenesisGO:0001756870.026
cellular amino acid metabolic processGO:000652070.026
astrocyte differentiationGO:004870810.026
symbiosis encompassing mutualism through parasitismGO:004440340.026
regulation of glucose importGO:004632410.026
guanosine containing compound metabolic processGO:190106840.026
hormone secretionGO:004687920.026
positive regulation of cell deathGO:0010942290.026
negative regulation of macromolecule metabolic processGO:0010605760.026
response to corticosteroidGO:003196010.025
positive regulation of canonical wnt signaling pathwayGO:009026340.025
transcription dna templatedGO:00063511810.025
regulation of dna replicationGO:000627530.025
lipid storageGO:001991510.025
cytokinesisGO:000091030.025
positive regulation of myeloid cell differentiationGO:004563920.025
carbohydrate homeostasisGO:003350010.025
regulation of circadian rhythmGO:004275240.025
anterior posterior pattern specificationGO:00099521520.025
cellular nitrogen compound biosynthetic processGO:00442712180.025
deathGO:00162651210.025
negative regulation of protein kinase activityGO:000646940.025
glucose homeostasisGO:004259310.025
cellular component movementGO:00069283350.024
programmed cell deathGO:00125011190.024
response to carbohydrateGO:000974330.024
fertilizationGO:000956630.024
positive regulation of immune effector processGO:000269930.024
response to drugGO:004249330.024
multi organism processGO:00517041340.024
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.024
regulation of cell killingGO:003134120.024
female sex differentiationGO:004666040.024
regulation of protein catabolic processGO:004217610.024
lipid catabolic processGO:001604240.024
nuclear migrationGO:000709730.024
response to amino acidGO:004320020.024
neuron projection morphogenesisGO:00488121610.024
development of primary female sexual characteristicsGO:004654540.024
carboxylic acid metabolic processGO:0019752220.024
negative regulation of synapse assemblyGO:005196420.023
regulation of endopeptidase activityGO:0052548230.023
gtp catabolic processGO:000618420.023
cellular protein metabolic processGO:00442671290.023
response to external biotic stimulusGO:0043207970.023
sleepGO:003043110.023
regulation of nitrogen compound metabolic processGO:00511712510.023
negative regulation of kinase activityGO:003367340.023
renal system developmentGO:0072001940.023
protein polymerizationGO:005125840.023
hepaticobiliary system developmentGO:0061008980.023
cellular response to chemical stimulusGO:00708871570.023
positive regulation of metabolic processGO:00098931080.023
internal protein amino acid acetylationGO:000647520.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.023
segmentationGO:0035282970.022
positive regulation of cell cycleGO:004578730.022
cellular response to extracellular stimulusGO:003166820.022
cortical cytoskeleton organizationGO:003086510.022
cellular carbohydrate metabolic processGO:004426240.022
response to hexoseGO:000974630.022
positive regulation of secretionGO:005104710.022
protein heterooligomerizationGO:005129110.022
regulation of protein localization to plasma membraneGO:190307610.022
regulation of purine nucleotide catabolic processGO:003312120.022
peptidyl lysine acetylationGO:001839420.022
regulation of nucleoside metabolic processGO:000911820.022
cell matrix adhesionGO:000716040.022
regulation of rna biosynthetic processGO:20011412130.022
exocytosisGO:000688710.021
regulation of erythrocyte differentiationGO:004564620.021
modification of morphology or physiology of other organismGO:003582140.021
regulation of reproductive processGO:200024140.021
cell deathGO:00082191210.021
positive regulation of nitrogen compound metabolic processGO:0051173690.021
regulation of response to biotic stimulusGO:000283120.021
embryonic organ developmentGO:00485683810.021
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.021
regulation of synapse assemblyGO:005196330.021
negative regulation of catabolic processGO:000989530.021
proteolysisGO:0006508380.021
positive regulation of stress activated mapk cascadeGO:003287430.021
regulation of multicellular organismal processGO:00512392770.021
cell morphogenesisGO:00009022890.021
regulation of nucleobase containing compound metabolic processGO:00192192500.021
negative regulation of protein serine threonine kinase activityGO:007190120.021
mitotic dna integrity checkpointGO:004477440.020
locomotionGO:00400113130.020
regulation of autophagyGO:001050630.020
positive regulation of jun kinase activityGO:004350720.020
microtubule organizing center organizationGO:003102310.020
endocrine processGO:005088620.020
single fertilizationGO:000733830.020
morphogenesis of an epitheliumGO:00020093330.020
cell motilityGO:00488702440.020
positive regulation of secretion by cellGO:190353210.020
cellular lipid catabolic processGO:004424230.020
protein secretionGO:000930610.020
regulation of nucleotide catabolic processGO:003081120.020
cell killingGO:000190620.020
peptidyl serine phosphorylationGO:001810510.020
negative regulation of cytoplasmic transportGO:190365020.020
apoptotic processGO:00069151160.020
transcription from rna polymerase ii promoterGO:0006366800.020
negative regulation of intracellular transportGO:003238730.020
cellular response to nutrient levelsGO:003166920.019
protein acylationGO:004354330.019
response to radiationGO:0009314510.019
response to endogenous stimulusGO:0009719830.019
muscle tissue developmentGO:00605371100.019
positive regulation of apoptotic signaling pathwayGO:200123510.019
somatic muscle developmentGO:000752540.019
b cell differentiationGO:003018310.019
positive regulation of muscle cell differentiationGO:005114910.019
positive regulation of gtpase activityGO:004354710.019
organelle fusionGO:004828430.019
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.019
regulation of microtubule cytoskeleton organizationGO:007050730.019
nucleic acid metabolic processGO:00903042440.019
regulation of jak stat cascadeGO:004642530.019
protein modification processGO:00362111000.019
regulation of gtpase activityGO:004308720.019
regulation of meiotic cell cycleGO:005144510.019
cytoplasm organizationGO:000702840.019
regulation of proteolysisGO:0030162240.019
response to glucoseGO:000974930.019
system processGO:00030081850.019
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.018
cell substrate adhesionGO:003158940.018
cell part morphogenesisGO:00329902460.018
mitochondrial transportGO:000683920.018
response to uvGO:000941130.018
regulation of peptidyl tyrosine phosphorylationGO:005073010.018
regulation of production of molecular mediator of immune responseGO:000270010.018
response to nutrientGO:000758430.018
cytoskeleton dependent cytokinesisGO:006164030.018
b cell mediated immunityGO:001972430.018
purine ribonucleoside monophosphate catabolic processGO:000916940.018
regulation of protein modification by small protein conjugation or removalGO:190332030.018
regulation of organ growthGO:004662030.018
regulation of bindingGO:005109830.018
germ line stem cell maintenanceGO:003071820.018
positive regulation of neuron apoptotic processGO:004352510.018
negative regulation of metabolic processGO:0009892860.018
regulation of myotube differentiationGO:001083020.018
negative regulation of cellular catabolic processGO:003133030.017
protein complex localizationGO:003150310.017
taxisGO:00423301090.017
spindle assembly involved in mitosisGO:009030710.017
adherens junction maintenanceGO:003433420.017
cognitionGO:005089010.017
centrosome duplicationGO:005129810.017
regulation of i kappab kinase nf kappab signalingGO:004312240.017
regulation of response to oxidative stressGO:190288220.017
camera type eye developmentGO:00430102220.017
positive regulation of neuron deathGO:190121610.017
positive regulation of protein polymerizationGO:003227320.017
positive regulation of cellular catabolic processGO:003133130.017
positive regulation of cellular amine metabolic processGO:003324000.017
signal transduction in absence of ligandGO:003803410.017
regulation of fatty acid metabolic processGO:001921710.017
vacuolar transportGO:000703420.017
negative regulation of nucleocytoplasmic transportGO:004682320.017
negative regulation of small gtpase mediated signal transductionGO:005105810.017
single organism organelle organizationGO:19025891990.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
growthGO:00400071740.017
positive regulation of cytoskeleton organizationGO:005149530.017
female gonad developmentGO:000858540.017
regionalizationGO:00030022740.017
regulation of signalingGO:00230512350.016
positive regulation of catabolic processGO:000989640.016
neuroblast fate commitmentGO:001401710.016
synaptic growth at neuromuscular junctionGO:005112420.016
regulation of metal ion transportGO:001095940.016
regulation of dendrite developmentGO:005077330.016
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.016
cortical actin cytoskeleton organizationGO:003086610.016
ovulation cycleGO:004269820.016
organic substance transportGO:0071702580.016
meiotic cell cycle processGO:190304630.016
regulation of carbohydrate metabolic processGO:000610940.016
positive regulation of cell adhesionGO:004578510.016
establishment of localization in cellGO:0051649770.016
spindle assemblyGO:005122520.016
regulation of blood vessel sizeGO:005088020.016
vasculature developmentGO:00019442780.016
response to antibioticGO:004667710.016
regulation of programmed cell deathGO:00430671010.016
response to hydrogen peroxideGO:004254230.016
regulation of cellular biosynthetic processGO:00313262450.016
cellular response to starvationGO:000926710.016
regulation of tube sizeGO:003515020.016
organelle assemblyGO:00709251100.016
regulation of cellular component organizationGO:0051128860.016
p38mapk cascadeGO:003806610.015
regulation of catalytic activityGO:0050790550.015
regulation of cellular carbohydrate metabolic processGO:001067540.015
localization of cellGO:00516742440.015
peptidyl serine modificationGO:001820920.015
central nervous system developmentGO:00074173870.015
protein stabilizationGO:005082120.015
cellular component disassemblyGO:002241110.015
mitotic dna damage checkpointGO:004477340.015
entrainment of circadian clockGO:000964920.015
entrainment of circadian clock by photoperiodGO:004315310.015
negative regulation of autophagyGO:001050710.015
negative regulation of map kinase activityGO:004340720.015
phagocytosis engulfmentGO:000691110.015
skeletal system morphogenesisGO:00487051020.015
embryonic skeletal system morphogenesisGO:0048704930.015
regulation of gtp catabolic processGO:003312420.015
hormone transportGO:000991420.015
regulation of catenin import into nucleusGO:003541220.015
regulation of cell communicationGO:00106462320.015
regulation of stem cell proliferationGO:007209120.015
antimicrobial humoral responseGO:001973020.015
sensory perception of chemical stimulusGO:000760630.015
negative regulation of signalingGO:0023057960.015
regulation of organelle assemblyGO:190211540.015
rna localizationGO:000640340.015
response to monosaccharideGO:003428430.015
striated muscle cell developmentGO:00550021080.015
negative regulation of programmed cell deathGO:0043069580.015
regulation of blood pressureGO:000821710.015
somatic stem cell maintenanceGO:003501910.015
sensory organ developmentGO:00074233930.015
positive regulation of nucleoside metabolic processGO:004597910.015
cilium organizationGO:0044782710.015
circadian sleep wake cycle processGO:002241020.015
regulation of transportGO:0051049450.015
smooth muscle contractionGO:000693920.015
positive regulation of inflammatory responseGO:005072910.014
positive regulation of purine nucleotide catabolic processGO:003312310.014
negative regulation of defense responseGO:003134820.014
regulation of cell shapeGO:000836010.014
regulation of epithelial cell proliferationGO:005067830.014
regulation of protein polymerizationGO:003227120.014
regulation of cellular response to oxidative stressGO:190040720.014
regulation of response to cytokine stimulusGO:006075930.014
negative regulation of response to stimulusGO:00485851040.014
organism emergence from protective structureGO:007168440.014
germ line stem cell divisionGO:004207810.014
homeostatic processGO:00425921420.014
photoperiodismGO:0009648110.014
regulation of skeletal muscle tissue developmentGO:004864140.014
negative regulation of cell communicationGO:0010648960.014
negative regulation of cytokine productionGO:000181810.014
response to bacteriumGO:0009617580.014
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.014
protein homooligomerizationGO:005126030.014
negative regulation of intracellular protein transportGO:009031730.014
organic cyclic compound biosynthetic processGO:19013622230.014
cellular localizationGO:0051641970.014
actin polymerization or depolymerizationGO:000815420.014
i kappab kinase nf kappab signalingGO:000724940.014
developmental growthGO:00485891660.014
cellular protein modification processGO:00064641000.014
lateral inhibitionGO:004633110.014
negative regulation of cell deathGO:0060548600.014
medulla oblongata developmentGO:002155040.014
negative regulation of cellular metabolic processGO:0031324770.014
membrane invaginationGO:001032410.014
regulation of establishment of protein localization to plasma membraneGO:009000310.014
g1 s transition of mitotic cell cycleGO:000008210.014
cell cycle arrestGO:000705010.014
regulation of wound healingGO:006104120.014
reactive oxygen species metabolic processGO:007259360.013
endosomal transportGO:001619720.013
hatchingGO:003518840.013
regulation of molecular functionGO:0065009700.013
regulation of cellular protein metabolic processGO:0032268520.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
ventricular cardiac muscle tissue developmentGO:000322930.013
response to ketoneGO:190165410.013
positive regulation of dna metabolic processGO:005105410.013
cellular response to organic substanceGO:00713101050.013
positive regulation of programmed cell deathGO:0043068290.013
lymphocyte proliferationGO:004665110.013
regulation of multicellular organismal developmentGO:20000262230.013
phosphate containing compound metabolic processGO:00067961080.013
killing of cells of other organismGO:003164010.013
amino acid transportGO:000686520.013
negative regulation of epithelial cell proliferationGO:005068010.013
regulation of synaptic plasticityGO:004816710.013
negative regulation of protein transportGO:005122430.013
positive regulation of notch signaling pathwayGO:004574730.013
tissue remodelingGO:004877140.013
cellular response to lipopolysaccharideGO:007122230.013
circadian sleep wake cycle sleepGO:005080210.013
peptidyl threonine phosphorylationGO:001810710.013
regulation of cell projection assemblyGO:006049140.013
spermatid developmentGO:000728620.013
regulation of circadian sleep wake cycleGO:004274910.013
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.013
positive regulation of striated muscle cell differentiationGO:005115510.013
er nucleus signaling pathwayGO:000698420.013
cell cycle g1 s phase transitionGO:004484310.013
alpha amino acid metabolic processGO:190160530.013
glial cell migrationGO:000834730.013
carboxylic acid catabolic processGO:004639530.013
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.013
organelle organizationGO:00069962270.013
camera type eye morphogenesisGO:00485931080.013
positive regulation of multi organism processGO:004390230.013
nucleoside monophosphate catabolic processGO:000912540.013
regulation of cell differentiationGO:00455951420.013
muscle cell differentiationGO:00426921390.013
response to alkaloidGO:004327920.013

cflar disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
cardiovascular system diseaseDOID:128700.030
myopathyDOID:42300.018
muscle tissue diseaseDOID:6600.018
musculoskeletal system diseaseDOID:1700.018
muscular diseaseDOID:008000000.018
nervous system diseaseDOID:86300.017
heart diseaseDOID:11400.017
intrinsic cardiomyopathyDOID:006003600.017
cardiomyopathyDOID:005070000.017
organ system cancerDOID:005068600.015
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
immune system diseaseDOID:291400.013