IMP: Integrative Multi-species Prediction

Danio rerio

35 known processes

crabp2a

cellular retinoic acid binding protein 2, a

(Aliases: crabp2,sb:cb434,wu:fc51a11,cb432,cb434,zgc:110496,MGC110496)

Entrez: 171480
Ensembl: ENSDARG00000040923
ZFIN: ZDB-GENE-020320-4
UniProtKB: Q801Y4

Process Predictions
Disease Predictions

crabp2a biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
embryonic organ development	GO:0048568	381	0.999	Zebrafish
hindbrain development	GO:0030902	91	0.996
chordate embryonic development	GO:0043009	271	0.993
sensory organ development	GO:0007423	393	0.990
tube morphogenesis	GO:0035239	349	0.986	Zebrafish
signal transduction	GO:0007165	455	0.984
regulation of response to stimulus	GO:0048583	269	0.982
neuron development	GO:0048666	262	0.981	Mouse
embryonic organ morphogenesis	GO:0048562	274	0.975	Zebrafish
hindbrain morphogenesis	GO:0021575	22	0.974
positive regulation of biological process	GO:0048518	253	0.972	Mouse
skeletal system development	GO:0001501	181	0.962
larval development	GO:0002164	2	0.957
intracellular receptor signaling pathway	GO:0030522	30	0.956
response to vitamin b3	GO:0033552	2	0.955	Zebrafish
morphogenesis of an epithelium	GO:0002009	333	0.952	Zebrafish
nitrogen compound metabolic process	GO:0006807	319	0.952
brain development	GO:0007420	293	0.952
regulation of multicellular organismal development	GO:2000026	223	0.944	Mouse
macromolecule biosynthetic process	GO:0009059	227	0.937
locomotion	GO:0040011	313	0.927	Worm
heart development	GO:0007507	313	0.925	Zebrafish
muscle cell differentiation	GO:0042692	139	0.925
skin development	GO:0043588	54	0.922
epidermis development	GO:0008544	48	0.922
positive regulation of biosynthetic process	GO:0009891	68	0.920
ear development	GO:0043583	127	0.905
gland development	GO:0048732	143	0.904
digestive system development	GO:0055123	289	0.903
digestive tract development	GO:0048565	265	0.902
positive regulation of cellular process	GO:0048522	201	0.899	Mouse
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	68	0.889
heart morphogenesis	GO:0003007	156	0.884	Zebrafish
positive regulation of macromolecule biosynthetic process	GO:0010557	59	0.881
transcription dna templated	GO:0006351	181	0.873
regulation of macromolecule metabolic process	GO:0060255	317	0.872
organic cyclic compound metabolic process	GO:1901360	301	0.869
regionalization	GO:0003002	274	0.858
fin development	GO:0033333	77	0.852
regulation of biological quality	GO:0065008	263	0.849	Mouse Worm
maintenance of location	GO:0051235	4	0.841	Worm
embryo development ending in birth or egg hatching	GO:0009792	271	0.835
appendage development	GO:0048736	80	0.828	Mouse
positive regulation of gene expression	GO:0010628	71	0.825
stem cell development	GO:0048864	82	0.817
regulation of cell communication	GO:0010646	232	0.812
camera type eye development	GO:0043010	222	0.811
cell part morphogenesis	GO:0032990	246	0.809	Mouse
cell surface receptor signaling pathway	GO:0007166	325	0.803
eye development	GO:0001654	277	0.796
specification of symmetry	GO:0009799	204	0.790	Zebrafish
positive regulation of cellular biosynthetic process	GO:0031328	68	0.790
embryonic cranial skeleton morphogenesis	GO:0048701	90	0.784
embryonic skeletal system development	GO:0048706	97	0.780
regulation of nucleobase containing compound metabolic process	GO:0019219	250	0.778
regulation of anatomical structure morphogenesis	GO:0022603	130	0.764	Mouse
embryonic skeletal system morphogenesis	GO:0048704	93	0.762
axon development	GO:0061564	166	0.758	Mouse
neuron projection development	GO:0031175	180	0.753	Mouse
embryonic viscerocranium morphogenesis	GO:0048703	52	0.752
regulation of transcription from rna polymerase ii promoter	GO:0006357	114	0.741
regulation of rna biosynthetic process	GO:2001141	213	0.737
appendage morphogenesis	GO:0035107	56	0.713	Mouse
retina morphogenesis in camera type eye	GO:0060042	79	0.708
regulation of signaling	GO:0023051	235	0.706
epithelial tube morphogenesis	GO:0060562	148	0.693	Zebrafish
cellular nitrogen compound metabolic process	GO:0034641	290	0.684
cellular nitrogen compound biosynthetic process	GO:0044271	218	0.682
cell morphogenesis	GO:0000902	289	0.676	Mouse
neural crest cell differentiation	GO:0014033	72	0.675
biosynthetic process	GO:0009058	294	0.670
cardiac muscle cell differentiation	GO:0055007	30	0.662
regulation of rna metabolic process	GO:0051252	224	0.659
establishment of localization	GO:0051234	244	0.649
retinoic acid receptor signaling pathway	GO:0048384	16	0.646
rhombomere development	GO:0021546	19	0.631
neuron projection guidance	GO:0097485	86	0.631
single organism localization	GO:1902578	225	0.620
response to chemical	GO:0042221	320	0.616	Zebrafish
cell migration involved in heart development	GO:0060973	22	0.613
cardiac muscle tissue development	GO:0048738	48	0.609
cellular biosynthetic process	GO:0044249	286	0.609
regulation of primary metabolic process	GO:0080090	311	0.582
striated muscle cell differentiation	GO:0051146	129	0.558
transcription from rna polymerase ii promoter	GO:0006366	80	0.556
central nervous system development	GO:0007417	387	0.548
response to lipid	GO:0033993	60	0.536	Zebrafish
cell migration	GO:0016477	237	0.532
heterocycle metabolic process	GO:0046483	290	0.528
hard palate development	GO:0060022	4	0.524
rna metabolic process	GO:0016070	219	0.519
cellular component morphogenesis	GO:0032989	336	0.519	Mouse
axonogenesis	GO:0007409	152	0.518	Mouse
neuron differentiation	GO:0030182	353	0.518	Mouse
positive regulation of cellular metabolic process	GO:0031325	94	0.517
lipid storage	GO:0019915	1	0.516	Worm
brain morphogenesis	GO:0048854	18	0.507
reproductive process	GO:0022414	40	0.505
immune system process	GO:0002376	241	0.502
positive regulation of rna metabolic process	GO:0051254	59	0.495
regulation of signal transduction	GO:0009966	225	0.494
chemotaxis	GO:0006935	104	0.481
camera type eye morphogenesis	GO:0048593	108	0.480
regulation of metabolic process	GO:0019222	359	0.479
protein secretion	GO:0009306	1	0.478
response to hormone	GO:0009725	48	0.466	Zebrafish
organonitrogen compound metabolic process	GO:1901564	74	0.464
mesenchymal cell development	GO:0014031	78	0.432
stress fiber assembly	GO:0043149	5	0.432
mechanoreceptor differentiation	GO:0042490	37	0.429
positive regulation of nucleic acid templated transcription	GO:1903508	57	0.425
embryonic appendage morphogenesis	GO:0035113	30	0.410	Mouse
blood vessel morphogenesis	GO:0048514	216	0.397
cell proliferation in forebrain	GO:0021846	3	0.396
sensory organ morphogenesis	GO:0090596	200	0.396
regulation of cellular biosynthetic process	GO:0031326	245	0.390
positive regulation of metabolic process	GO:0009893	108	0.389
regulation of cellular metabolic process	GO:0031323	320	0.386
aging	GO:0007568	2	0.386	Worm
cellular component biogenesis	GO:0044085	178	0.386
muscle structure development	GO:0061061	196	0.368
response to nutrient	GO:0007584	3	0.348	Zebrafish
pigmentation	GO:0043473	85	0.348
positive regulation of nucleobase containing compound metabolic process	GO:0045935	69	0.338
positive regulation of nitrogen compound metabolic process	GO:0051173	69	0.335
reproduction	GO:0000003	40	0.334
skeletal system morphogenesis	GO:0048705	102	0.333
anatomical structure arrangement	GO:0048532	2	0.329
nucleobase containing compound biosynthetic process	GO:0034654	205	0.316
neural crest cell development	GO:0014032	62	0.311
generation of neurons	GO:0048699	385	0.303	Mouse
mesenchyme development	GO:0060485	127	0.301
embryonic limb morphogenesis	GO:0030326	2	0.300	Mouse
embryonic heart tube development	GO:0035050	133	0.299	Zebrafish
digestive tract morphogenesis	GO:0048546	231	0.289
mesenchymal cell differentiation	GO:0048762	87	0.285
cardiocyte differentiation	GO:0035051	44	0.282
response to oxygen containing compound	GO:1901700	55	0.278	Zebrafish
regulation of multicellular organismal process	GO:0051239	277	0.271	Mouse
photoreceptor cell development	GO:0042461	40	0.271
negative regulation of cellular process	GO:0048523	283	0.269
positive regulation of transport	GO:0051050	2	0.268
rhombomere morphogenesis	GO:0021593	17	0.267
regulation of neurogenesis	GO:0050767	87	0.264	Mouse
regulation of binding	GO:0051098	3	0.264
liver development	GO:0001889	96	0.263
retina development in camera type eye	GO:0060041	146	0.260
cell fate commitment	GO:0045165	99	0.259
multicellular organism growth	GO:0035264	4	0.258
positive regulation of transcription dna templated	GO:0045893	57	0.257
epithelial tube formation	GO:0072175	19	0.254
response to fatty acid	GO:0070542	5	0.253	Zebrafish
response to external stimulus	GO:0009605	264	0.251	Zebrafish
cellular aromatic compound metabolic process	GO:0006725	295	0.251
inner ear development	GO:0048839	126	0.249
nucleic acid templated transcription	GO:0097659	181	0.246
tissue migration	GO:0090130	37	0.240
cellular response to chemical stimulus	GO:0070887	157	0.238
regulation of localization	GO:0032879	104	0.236
regulation of developmental process	GO:0050793	247	0.236	Mouse
organic substance biosynthetic process	GO:1901576	289	0.235
blood vessel development	GO:0001568	246	0.234
response to abiotic stimulus	GO:0009628	122	0.233
cell migration in hindbrain	GO:0021535	7	0.232
macromolecule catabolic process	GO:0009057	15	0.230
cellular response to estrogen stimulus	GO:0071391	24	0.219
ear morphogenesis	GO:0042471	64	0.218
response to vitamin	GO:0033273	3	0.216	Zebrafish
developmental growth	GO:0048589	166	0.214	Mouse
positive regulation of macromolecule metabolic process	GO:0010604	93	0.207
positive regulation of muscle tissue development	GO:1901863	1	0.204
organic acid metabolic process	GO:0006082	31	0.200	Mouse
determination of bilateral symmetry	GO:0009855	204	0.199	Zebrafish
tube formation	GO:0035148	25	0.199
multicellular organism reproduction	GO:0032504	35	0.199
striated muscle cell development	GO:0055002	108	0.198
peripheral nervous system development	GO:0007422	55	0.198
dendrite development	GO:0016358	9	0.196
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	50	0.195
endocrine system development	GO:0035270	65	0.194
regulation of gene expression	GO:0010468	265	0.192
aorta development	GO:0035904	4	0.192
photoreceptor cell differentiation	GO:0046530	55	0.191
epidermal cell differentiation	GO:0009913	36	0.191
determination of left right symmetry	GO:0007368	179	0.190	Zebrafish
multicellular organismal reproductive process	GO:0048609	35	0.189
inner ear receptor cell development	GO:0060119	20	0.186
neuron projection morphogenesis	GO:0048812	161	0.184	Mouse
muscle cell development	GO:0055001	115	0.183
striated muscle tissue development	GO:0014706	110	0.182
single organism metabolic process	GO:0044710	217	0.179	Mouse
cell motility	GO:0048870	244	0.178
dendrite morphogenesis	GO:0048813	5	0.178
stem cell differentiation	GO:0048863	117	0.175
nucleobase containing compound metabolic process	GO:0006139	274	0.175
regulation of protein catabolic process	GO:0042176	1	0.175
eye morphogenesis	GO:0048592	144	0.172
bmp signaling pathway	GO:0030509	52	0.169
ameboidal type cell migration	GO:0001667	143	0.169
small molecule metabolic process	GO:0044281	77	0.168	Mouse
system process	GO:0003008	185	0.168
neural tube development	GO:0021915	62	0.166
cellular response to biotic stimulus	GO:0071216	3	0.160
negative regulation of axon regeneration	GO:0048681	4	0.160
head development	GO:0060322	303	0.159
enzyme linked receptor protein signaling pathway	GO:0007167	106	0.158
endocardial cushion formation	GO:0003272	2	0.155
cellular response to hormone stimulus	GO:0032870	39	0.155
macromolecular complex subunit organization	GO:0043933	74	0.155
axon guidance	GO:0007411	86	0.154
heterocycle biosynthetic process	GO:0018130	215	0.151
regulation of establishment of protein localization	GO:0070201	4	0.150
pronephros development	GO:0048793	69	0.150
cell morphogenesis involved in differentiation	GO:0000904	195	0.147	Mouse
cranial nerve development	GO:0021545	42	0.147
midbrain development	GO:0030901	28	0.146
stem cell maintenance	GO:0019827	4	0.146
muscle tissue development	GO:0060537	110	0.145
regulation of epithelial cell proliferation	GO:0050678	3	0.141
negative regulation of cell death	GO:0060548	60	0.140
otic vesicle development	GO:0071599	42	0.139
cell death	GO:0008219	121	0.139
cellular macromolecule metabolic process	GO:0044260	391	0.132
gastrulation	GO:0007369	208	0.132
aromatic compound biosynthetic process	GO:0019438	217	0.132
cellular response to retinoic acid	GO:0071300	1	0.127
organ formation	GO:0048645	17	0.123
response to biotic stimulus	GO:0009607	97	0.123
phosphorus metabolic process	GO:0006793	109	0.121
epithelial to mesenchymal transition	GO:0001837	21	0.121
organic substance transport	GO:0071702	58	0.119
defense response to gram negative bacterium	GO:0050829	8	0.118
taxis	GO:0042330	109	0.117
keratinocyte differentiation	GO:0030216	0	0.116
muscle organ development	GO:0007517	101	0.116
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	48	0.115
oxoacid metabolic process	GO:0043436	31	0.114	Mouse
embryonic retina morphogenesis in camera type eye	GO:0060059	22	0.113
regulation of nitrogen compound metabolic process	GO:0051171	251	0.112
regulation of programmed cell death	GO:0043067	101	0.111
catabolic process	GO:0009056	32	0.109
neural tube formation	GO:0001841	16	0.109
negative regulation of nucleobase containing compound metabolic process	GO:0045934	59	0.109
wnt signaling pathway	GO:0016055	80	0.108
cellular response to endogenous stimulus	GO:0071495	68	0.106
cellular response to vitamin	GO:0071295	1	0.105
negative regulation of programmed cell death	GO:0043069	58	0.104
cell proliferation in hindbrain	GO:0021534	4	0.104
cell matrix adhesion	GO:0007160	4	0.104
epithelial cell morphogenesis	GO:0003382	2	0.102
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	22	0.099
negative regulation of biological process	GO:0048519	304	0.097
regulation of nervous system development	GO:0051960	90	0.095	Mouse
collagen metabolic process	GO:0032963	2	0.095
pancreas development	GO:0031016	84	0.093
central nervous system myelination	GO:0022010	2	0.093
carbohydrate derivative metabolic process	GO:1901135	61	0.092
pectoral fin morphogenesis	GO:0035138	29	0.092
somitogenesis	GO:0001756	87	0.090
lens development in camera type eye	GO:0002088	22	0.088
regulation of cellular component organization	GO:0051128	86	0.087	Mouse
vasculature development	GO:0001944	278	0.086
epiboly involved in gastrulation with mouth forming second	GO:0055113	35	0.084
organelle organization	GO:0006996	227	0.084
regulation of stem cell differentiation	GO:2000736	4	0.084
regulation of biosynthetic process	GO:0009889	250	0.084
regulation of cellular macromolecule biosynthetic process	GO:2000112	222	0.083
positive regulation of cytokine production	GO:0001819	2	0.083
peripheral nervous system neuron differentiation	GO:0048934	28	0.083
heart looping	GO:0001947	94	0.083	Zebrafish
positive regulation of nervous system development	GO:0051962	25	0.082	Mouse
cellular response to acid chemical	GO:0071229	8	0.082
regulation of axonogenesis	GO:0050770	32	0.081	Mouse
regulation of protein localization to nucleus	GO:1900180	2	0.080
rhombomere formation	GO:0021594	12	0.079
notochord development	GO:0030903	54	0.079
morphogenesis of embryonic epithelium	GO:0016331	30	0.079
myeloid cell differentiation	GO:0030099	86	0.078
cell morphogenesis involved in neuron differentiation	GO:0048667	163	0.078	Mouse
neuron fate commitment	GO:0048663	26	0.078
negative regulation of transcription dna templated	GO:0045892	45	0.077
positive regulation of molecular function	GO:0044093	33	0.077
morphogenesis of an epithelial sheet	GO:0002011	49	0.076
positive regulation of striated muscle tissue development	GO:0045844	1	0.075
primary neural tube formation	GO:0014020	1	0.075
cellular protein metabolic process	GO:0044267	129	0.075
regulation of anatomical structure size	GO:0090066	33	0.074	Mouse
intracellular estrogen receptor signaling pathway	GO:0030520	3	0.074
sex determination	GO:0007530	1	0.073
otic vesicle morphogenesis	GO:0071600	34	0.073
response to steroid hormone	GO:0048545	35	0.073
positive regulation of neural precursor cell proliferation	GO:2000179	1	0.073
negative regulation of signal transduction	GO:0009968	94	0.072
positive regulation of gliogenesis	GO:0014015	2	0.071
rhombomere 5 development	GO:0021571	4	0.070
mitotic cell cycle process	GO:1903047	48	0.070
fat soluble vitamin metabolic process	GO:0006775	4	0.070
immune system development	GO:0002520	191	0.069
positive regulation of rna biosynthetic process	GO:1902680	57	0.069
localization of cell	GO:0051674	244	0.069
cellular response to organic substance	GO:0071310	105	0.068
axon ensheathment in central nervous system	GO:0032291	2	0.068
regulation of transcription dna templated	GO:0006355	213	0.068
myeloid leukocyte differentiation	GO:0002573	15	0.068
regulation of protein metabolic process	GO:0051246	56	0.067
protein complex biogenesis	GO:0070271	30	0.067
cellular response to lipid	GO:0071396	39	0.066
organic substance catabolic process	GO:1901575	28	0.065
neuron recognition	GO:0008038	18	0.064
regulation of apoptotic process	GO:0042981	98	0.063
negative regulation of biosynthetic process	GO:0009890	55	0.063
stem cell division	GO:0017145	1	0.063
neural retina development	GO:0003407	49	0.063
distal tubule development	GO:0072017	1	0.063
negative regulation of collateral sprouting	GO:0048671	2	0.061
organic cyclic compound biosynthetic process	GO:1901362	223	0.061
connective tissue development	GO:0061448	99	0.061
macromolecule localization	GO:0033036	54	0.061	Worm
epithelial cell development	GO:0002064	42	0.060
regulation of cell morphogenesis involved in differentiation	GO:0010769	38	0.059	Mouse
regulation of cell shape	GO:0008360	1	0.059
negative regulation of apoptotic process	GO:0043066	55	0.058
gliogenesis	GO:0042063	45	0.058
regulation of nucleic acid templated transcription	GO:1903506	213	0.058
gamete generation	GO:0007276	33	0.058
negative regulation of macromolecule biosynthetic process	GO:0010558	48	0.058
cell projection organization	GO:0030030	284	0.058	Mouse
negative regulation of metabolic process	GO:0009892	86	0.056
positive regulation of secretion by cell	GO:1903532	1	0.056
artery development	GO:0060840	22	0.056
oxidation reduction process	GO:0055114	41	0.056
regulation of cytokine production	GO:0001817	3	0.055
response to estrogen	GO:0043627	27	0.055
otic vesicle formation	GO:0030916	27	0.054
regulation of cell morphogenesis	GO:0022604	42	0.053	Mouse
positive regulation of catabolic process	GO:0009896	4	0.053
cell cycle process	GO:0022402	53	0.053
protein modification process	GO:0036211	100	0.053
diterpenoid metabolic process	GO:0016101	15	0.053	Mouse
defense response	GO:0006952	47	0.053
response to prostaglandin	GO:0034694	5	0.052	Zebrafish
response to bacterium	GO:0009617	58	0.051
cellular amine metabolic process	GO:0044106	2	0.051
epithelial cell differentiation	GO:0030855	116	0.050
response to wounding	GO:0009611	116	0.050
body morphogenesis	GO:0010171	16	0.049
phosphorylation	GO:0016310	69	0.049
actin filament bundle assembly	GO:0051017	6	0.049
cellular response to steroid hormone stimulus	GO:0071383	31	0.049
response to acid chemical	GO:0001101	17	0.049	Zebrafish
startle response	GO:0001964	4	0.049
regulation of protein transport	GO:0051223	3	0.048
response to oxygen levels	GO:0070482	25	0.048
cellular macromolecule biosynthetic process	GO:0034645	224	0.047
growth	GO:0040007	174	0.047	Mouse
multi organism process	GO:0051704	134	0.047
axonal fasciculation	GO:0007413	11	0.047
regulation of protein modification by small protein conjugation or removal	GO:1903320	3	0.047
nerve development	GO:0021675	45	0.046
single organism reproductive process	GO:0044702	40	0.046
hair cell differentiation	GO:0035315	32	0.046
neurological system process	GO:0050877	62	0.046
renal system development	GO:0072001	94	0.045
response to external biotic stimulus	GO:0043207	97	0.045
skeletal muscle organ development	GO:0060538	78	0.045
metencephalon development	GO:0022037	27	0.045
regeneration	GO:0031099	91	0.044
negative regulation of neuron differentiation	GO:0045665	10	0.044
carboxylic acid metabolic process	GO:0019752	22	0.044	Mouse
protein localization	GO:0008104	40	0.043
positive regulation of secretion	GO:0051047	1	0.043
positive regulation of glial cell differentiation	GO:0045687	1	0.043
forebrain development	GO:0030900	96	0.043
single organismal cell cell adhesion	GO:0016337	29	0.043
eye photoreceptor cell differentiation	GO:0001754	45	0.043
retinal metabolic process	GO:0042574	3	0.042
kidney development	GO:0001822	92	0.042
behavior	GO:0007610	74	0.042
somite development	GO:0061053	96	0.042
negative regulation of cell development	GO:0010721	26	0.041
oligodendrocyte development	GO:0014003	7	0.039
dorsal ventral pattern formation	GO:0009953	125	0.039
positive regulation of locomotion	GO:0040017	14	0.039
bone development	GO:0060348	14	0.039
cellular component movement	GO:0006928	335	0.039
germ line stem cell maintenance	GO:0030718	2	0.038
regulation of epidermis development	GO:0045682	2	0.038
neuron projection extension	GO:1990138	45	0.038
homeostatic process	GO:0042592	142	0.038
regulation of protein ubiquitination	GO:0031396	3	0.038
cell cell signaling	GO:0007267	52	0.038
single organism transport	GO:0044765	206	0.038
pectoral fin development	GO:0033339	50	0.038
diencephalon development	GO:0021536	58	0.037
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	42	0.037
cell cycle	GO:0007049	93	0.036
regulation of multicellular organism growth	GO:0040014	4	0.036
response to hypoxia	GO:0001666	25	0.036
g1 s transition of mitotic cell cycle	GO:0000082	1	0.036
segmentation	GO:0035282	97	0.036
cytoskeleton organization	GO:0007010	96	0.035
single organism organelle organization	GO:1902589	199	0.035
notochord cell differentiation	GO:0060034	18	0.035
regulation of dendrite development	GO:0050773	3	0.035
positive regulation of muscle organ development	GO:0048636	1	0.035
negative regulation of macromolecule metabolic process	GO:0010605	76	0.034
inner ear receptor stereocilium organization	GO:0060122	8	0.034
regulation of retina development in camera type eye	GO:1902866	2	0.034
positive regulation of cellular component biogenesis	GO:0044089	3	0.034
positive regulation of cell fate specification	GO:0042660	1	0.033
urogenital system development	GO:0001655	97	0.033
response to extracellular stimulus	GO:0009991	10	0.033	Zebrafish
actomyosin structure organization	GO:0031032	53	0.033
spinal cord development	GO:0021510	46	0.033
establishment of localization in cell	GO:0051649	77	0.033
mesoderm development	GO:0007498	88	0.033
nucleic acid metabolic process	GO:0090304	244	0.032
epiboly	GO:0090504	41	0.032
positive regulation of developmental process	GO:0051094	50	0.031	Mouse
programmed cell death	GO:0012501	119	0.031
developmental pigmentation	GO:0048066	48	0.031
response to stress	GO:0006950	263	0.031
single organism nuclear import	GO:1902593	3	0.031
smooth muscle contraction	GO:0006939	2	0.030
regulation of cell development	GO:0060284	100	0.030	Mouse
hepaticobiliary system development	GO:0061008	98	0.030
negative regulation of cellular metabolic process	GO:0031324	77	0.029
response to organic cyclic compound	GO:0014070	51	0.029
cellular response to oxygen levels	GO:0071453	1	0.029
embryonic pectoral fin morphogenesis	GO:0035118	24	0.029
negative regulation of signaling	GO:0023057	96	0.029
regulation of cellular protein catabolic process	GO:1903362	1	0.029
protein import into nucleus	GO:0006606	3	0.028
cerebellum development	GO:0021549	17	0.028
regulation of hormone secretion	GO:0046883	2	0.028
cell cycle g1 s phase transition	GO:0044843	1	0.028
hematopoietic or lymphoid organ development	GO:0048534	191	0.028
cellular response to nutrient	GO:0031670	1	0.028
establishment of protein localization to organelle	GO:0072594	4	0.027
post embryonic development	GO:0009791	7	0.027
regulation of protein import into nucleus	GO:0042306	2	0.027
small gtpase mediated signal transduction	GO:0007264	8	0.027
cellular carbohydrate metabolic process	GO:0044262	4	0.027
cellular aldehyde metabolic process	GO:0006081	4	0.027
rna biosynthetic process	GO:0032774	181	0.027
cellular component assembly	GO:0022607	170	0.027
negative regulation of gene expression	GO:0010629	65	0.026
rho protein signal transduction	GO:0007266	5	0.026
optic nerve morphogenesis	GO:0021631	6	0.026
type b pancreatic cell proliferation	GO:0044342	1	0.026
positive regulation of stem cell proliferation	GO:2000648	1	0.025
apoptotic process	GO:0006915	116	0.025
protein complex assembly	GO:0006461	30	0.025
regulation of cell migration	GO:0030334	40	0.025
phagocytosis	GO:0006909	3	0.025
lipid localization	GO:0010876	11	0.024	Worm
neuroblast differentiation	GO:0014016	1	0.024
wound healing	GO:0042060	90	0.024
inner ear morphogenesis	GO:0042472	63	0.024
cellular response to fatty acid	GO:0071398	3	0.024
regulation of catalytic activity	GO:0050790	55	0.024
response to other organism	GO:0051707	97	0.024
eye photoreceptor cell development	GO:0042462	30	0.024
regulation of behavior	GO:0050795	24	0.024
positive regulation of neurogenesis	GO:0050769	24	0.023	Mouse
positive regulation of cell differentiation	GO:0045597	30	0.023	Mouse
negative regulation of protein transport	GO:0051224	3	0.023
establishment of cell polarity	GO:0030010	18	0.023
ventricular system development	GO:0021591	12	0.023
cellular response to molecule of bacterial origin	GO:0071219	3	0.023
cell migration to the midline involved in heart development	GO:0003318	12	0.023
response to ketone	GO:1901654	1	0.023
neural precursor cell proliferation	GO:0061351	20	0.022
axon extension	GO:0048675	45	0.022
gene expression	GO:0010467	252	0.022
regulation of blood vessel size	GO:0050880	2	0.022
adult behavior	GO:0030534	2	0.022
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	22	0.022
locus ceruleus development	GO:0021703	3	0.022
regulation of dendrite morphogenesis	GO:0048814	3	0.022
dna templated transcription initiation	GO:0006352	1	0.022
gastrulation with mouth forming second	GO:0001702	44	0.022
cellular response to extracellular stimulus	GO:0031668	2	0.022
protein complex subunit organization	GO:0071822	46	0.021
regulation of cell motility	GO:2000145	46	0.021
cerebellum formation	GO:0021588	2	0.021
regulation of locomotion	GO:0040012	55	0.021
regulation of cellular amino acid metabolic process	GO:0006521	0	0.021
inner ear receptor cell differentiation	GO:0060113	29	0.021
amine metabolic process	GO:0009308	2	0.021
glucose homeostasis	GO:0042593	1	0.021
cellular response to fluid shear stress	GO:0071498	1	0.021
cellular protein modification process	GO:0006464	100	0.021

crabp2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.149
bone disease	DOID:0080001	0.052
musculoskeletal system disease	DOID:17	0.052
connective tissue disease	DOID:65	0.052
bone development disease	DOID:0080006	0.028
osteochondrodysplasia	DOID:2256	0.028

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