Danio rerio

22 known processes

plce1

phospholipase C, epsilon 1

plce1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pronephric nephron developmentGO:0039019140.443
cell surface receptor signaling pathwayGO:00071663250.370
neuron differentiationGO:00301823530.360
regulation of macromolecule metabolic processGO:00602553170.326
digestive tract developmentGO:00485652650.322
pronephric glomerulus developmentGO:0039021130.266
blood vessel developmentGO:00015682460.225
cellular nitrogen compound metabolic processGO:00346412900.221
morphogenesis of a branching structureGO:0001763210.210
localization of cellGO:00516742440.210
regulation of multicellular organismal processGO:00512392770.210
nephron developmentGO:0072006310.209
cell motilityGO:00488702440.205
striated muscle cell developmentGO:00550021080.204
chemotaxisGO:00069351040.196
blood vessel morphogenesisGO:00485142160.194
glomerulus developmentGO:0032835270.193
striated muscle tissue developmentGO:00147061100.192
locomotionGO:00400113130.191
striated muscle cell differentiationGO:00511461290.189
response to abiotic stimulusGO:00096281220.178
epithelial cell differentiationGO:00308551160.173
nucleobase containing compound biosynthetic processGO:00346542050.172
ameboidal type cell migrationGO:00016671430.171
pronephros developmentGO:0048793690.164
post embryonic organ developmentGO:004856940.161
cellular component assemblyGO:00226071700.158
organic substance biosynthetic processGO:19015762890.156
cellular aromatic compound metabolic processGO:00067252950.154
embryonic skeletal system morphogenesisGO:0048704930.152
cellular macromolecule biosynthetic processGO:00346452240.150
glomerular basement membrane developmentGO:003283650.146
signal transductionGO:00071654550.140
cellular component movementGO:00069283350.134
muscle fiber developmentGO:0048747520.133
single organism metabolic processGO:00447102170.133
synaptic target recognitionGO:000803910.130
muscle cell differentiationGO:00426921390.129
positive regulation of cellular component biogenesisGO:004408930.126
regulation of rna biosynthetic processGO:20011412130.125
regulation of rna metabolic processGO:00512522240.122
embryonic viscerocranium morphogenesisGO:0048703520.122
epithelial cell developmentGO:0002064420.121
regulation of cellular biosynthetic processGO:00313262450.121
regulation of anatomical structure sizeGO:0090066330.120
positive regulation of cellular processGO:00485222010.120
tube morphogenesisGO:00352393490.117
multicellular organismal reproductive processGO:0048609350.115
transcription dna templatedGO:00063511810.114
cellular macromolecule metabolic processGO:00442603910.109
heterocycle biosynthetic processGO:00181302150.108
regulation of synapse assemblyGO:005196330.105
muscle structure developmentGO:00610611960.102
response to chemicalGO:00422213200.101
extracellular structure organizationGO:0043062270.100
larval developmentGO:000216420.099
regulation of metabolic processGO:00192223590.098
kidney developmentGO:0001822920.098
muscle cell developmentGO:00550011150.097
cognitionGO:005089010.093
heterocycle metabolic processGO:00464832900.093
response to light stimulusGO:0009416460.091
gastrulationGO:00073692080.091
regulation of anatomical structure morphogenesisGO:00226031300.089
single organismal cell cell adhesionGO:0016337290.089
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.089
nephric duct developmentGO:0072176130.088
epithelial tube morphogenesisGO:00605621480.087
single organism cell adhesionGO:0098602290.086
regulation of synapse organizationGO:005080730.085
cell adhesionGO:0007155400.085
regulation of nucleic acid templated transcriptionGO:19035062130.084
nephron tubule morphogenesisGO:007207810.083
nitrogen compound metabolic processGO:00068073190.081
membrane lipid biosynthetic processGO:004646720.081
vasculature developmentGO:00019442780.080
cell migrationGO:00164772370.080
small molecule metabolic processGO:0044281770.079
macromolecule biosynthetic processGO:00090592270.078
regulation of cellular metabolic processGO:00313233200.078
biological adhesionGO:0022610400.077
cell substrate adhesionGO:003158940.076
retinal ganglion cell axon guidanceGO:0031290350.074
positive regulation of biological processGO:00485182530.073
cellular nitrogen compound biosynthetic processGO:00442712180.069
cellular component biogenesisGO:00440851780.069
organic cyclic compound biosynthetic processGO:19013622230.069
axon guidanceGO:0007411860.069
agingGO:000756820.067
cell matrix adhesionGO:000716040.066
generation of neuronsGO:00486993850.066
phosphate containing compound metabolic processGO:00067961080.066
myotube cell developmentGO:0014904350.064
cellular biosynthetic processGO:00442492860.064
morphogenesis of an epitheliumGO:00020093330.064
regulation of cellular macromolecule biosynthetic processGO:20001122220.064
regulation of protein complex assemblyGO:004325430.063
regulation of primary metabolic processGO:00800903110.062
biosynthetic processGO:00090582940.062
regulation of cell migrationGO:0030334400.062
regulation of synaptic growth at neuromuscular junctionGO:000858210.061
regulation of locomotionGO:0040012550.060
regulation of macromolecule biosynthetic processGO:00105562250.060
heart developmentGO:00075073130.059
response to external stimulusGO:00096052640.057
regulation of biological qualityGO:00650082630.057
system processGO:00030081850.057
female gonad developmentGO:000858540.056
regulation of cellular component movementGO:0051270550.056
cell growthGO:0016049570.055
neuron developmentGO:00486662620.054
positive regulation of response to stimulusGO:0048584800.054
nucleic acid templated transcriptionGO:00976591810.053
muscle tissue developmentGO:00605371100.053
convergent extensionGO:00600261180.052
nephron epithelium developmentGO:0072009160.051
connective tissue developmentGO:0061448990.051
organonitrogen compound metabolic processGO:1901564740.051
response to carbohydrateGO:000974330.050
taxisGO:00423301090.050
response to alkaloidGO:004327920.049
central nervous system developmentGO:00074173870.049
development of primary female sexual characteristicsGO:004654540.049
cellular component morphogenesisGO:00329893360.048
guanosine containing compound metabolic processGO:190106840.048
regulation of transcription dna templatedGO:00063552130.047
regionalizationGO:00030022740.047
regulation of cell substrate adhesionGO:001081010.047
angiogenesisGO:00015251580.047
digestive system developmentGO:00551232890.046
synaptic growth at neuromuscular junctionGO:005112420.046
spermatid developmentGO:000728620.046
positive regulation of gene expressionGO:0010628710.046
multi organism processGO:00517041340.046
protein metabolic processGO:00195381830.045
brain developmentGO:00074202930.045
membrane lipid metabolic processGO:0006643100.045
regulation of cell differentiationGO:00455951420.044
branching morphogenesis of an epithelial tubeGO:0048754150.043
syncytium formationGO:0006949120.043
gamete generationGO:0007276330.043
sphingolipid metabolic processGO:000666590.042
embryo development ending in birth or egg hatchingGO:00097922710.042
erk1 and erk2 cascadeGO:007037140.042
head developmentGO:00603223030.042
actin filament polymerizationGO:003004120.041
enzyme linked receptor protein signaling pathwayGO:00071671060.041
rna metabolic processGO:00160702190.041
dorsal ventral pattern formationGO:00099531250.041
nucleobase containing compound metabolic processGO:00061392740.041
visual behaviorGO:0007632100.041
regulation of embryonic developmentGO:0045995470.040
regulation of nitrogen compound metabolic processGO:00511712510.040
cellular response to oxygen levelsGO:007145310.040
embryonic cranial skeleton morphogenesisGO:0048701900.040
skeletal muscle organ developmentGO:0060538780.040
regulation of erk1 and erk2 cascadeGO:007037240.039
cell differentiation involved in kidney developmentGO:0061005130.039
pronephric duct developmentGO:0039022130.039
negative regulation of protein phosphorylationGO:000193340.038
regulation of multicellular organismal developmentGO:20000262230.038
lipid catabolic processGO:001604240.038
embryonic organ developmentGO:00485683810.038
negative regulation of cellular processGO:00485232830.038
cellular component assembly involved in morphogenesisGO:00109271070.038
regulation of cell shapeGO:000836010.037
positive regulation of macromolecule metabolic processGO:0010604930.037
extrinsic apoptotic signaling pathwayGO:009719130.037
female sex differentiationGO:004666040.036
mechanosensory behaviorGO:000763820.036
organic cyclic compound metabolic processGO:19013603010.036
protein import into nucleusGO:000660630.036
developmental growthGO:00485891660.036
cell projection organizationGO:00300302840.036
single organism reproductive processGO:0044702400.036
eye developmentGO:00016542770.036
negative regulation of cell adhesionGO:000716260.036
epithelial cell morphogenesisGO:000338220.035
protein polymerizationGO:005125840.035
reproductive processGO:0022414400.035
chemosensory behaviorGO:000763510.034
extracellular matrix organizationGO:0030198270.033
skeletal system morphogenesisGO:00487051020.033
organonitrogen compound biosynthetic processGO:1901566470.033
branching morphogenesis of a nerveGO:004875540.033
immune system developmentGO:00025201910.032
regulation of developmental processGO:00507932470.032
skeletal muscle fiber developmentGO:0048741350.032
synaptic transmission cholinergicGO:000727140.032
epithelial cell differentiation involved in kidney developmentGO:0035850130.032
multi organism reproductive processGO:0044703360.032
response to hexoseGO:000974630.031
response to radiationGO:0009314510.031
negative chemotaxisGO:005091910.031
hormone secretionGO:004687920.031
neuron recognitionGO:0008038180.031
response to monosaccharideGO:003428430.030
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.030
response to stressGO:00069502630.029
regulation of signal transductionGO:00099662250.029
morphogenesis of an epithelial sheetGO:0002011490.029
cell fate commitmentGO:0045165990.029
positive regulation of signal transductionGO:0009967560.029
cellular response to hypoxiaGO:007145610.029
growthGO:00400071740.029
regulation of cellular carbohydrate metabolic processGO:001067540.029
negative regulation of biological processGO:00485193040.028
cell morphogenesisGO:00009022890.028
actin cytoskeleton organizationGO:0030036630.028
symbiosis encompassing mutualism through parasitismGO:004440340.028
gene expressionGO:00104672520.028
endosomal transportGO:001619720.028
regulation of cytokine productionGO:000181730.027
nucleic acid metabolic processGO:00903042440.027
axonogenesisGO:00074091520.026
chordate embryonic developmentGO:00430092710.026
spermatid differentiationGO:004851520.026
regulation of cell morphogenesisGO:0022604420.026
cellular carbohydrate metabolic processGO:004426240.026
mesoderm developmentGO:0007498880.026
positive regulation of erk1 and erk2 cascadeGO:007037420.026
skeletal muscle tissue developmentGO:0007519670.026
cellular response to chemical stimulusGO:00708871570.026
synapse organizationGO:0050808210.025
developmental cell growthGO:0048588520.025
motor neuron axon guidanceGO:0008045230.025
golgi vesicle transportGO:004819330.025
regulation of cell matrix adhesionGO:000195210.025
cellular response to decreased oxygen levelsGO:003629410.025
myoblast fusionGO:0007520100.025
convergent extension involved in gastrulationGO:0060027710.024
positive regulation of cell adhesionGO:004578510.024
macromolecular complex assemblyGO:0065003350.024
positive regulation of cellular metabolic processGO:0031325940.024
developmental process involved in reproductionGO:0003006270.024
cellular amide metabolic processGO:004360340.024
regulation of reproductive processGO:200024140.024
nuclear transportGO:005116940.024
cell morphogenesis involved in neuron differentiationGO:00486671630.024
adherens junction assemblyGO:003433310.024
vasculogenesisGO:0001570410.024
apoptotic process involved in developmentGO:190274220.024
negative regulation of protein kinase activityGO:000646940.024
regulation of response to stimulusGO:00485832690.023
positive regulation of biosynthetic processGO:0009891680.023
positive regulation of metabolic processGO:00098931080.023
regulation of biosynthetic processGO:00098892500.023
gtp metabolic processGO:004603940.023
negative regulation of kinase activityGO:003367340.023
cellular response to organic substanceGO:00713101050.023
viral processGO:001603210.023
skeletal system developmentGO:00015011810.023
regulation of organ morphogenesisGO:2000027350.023
pronephros morphogenesisGO:0072114140.023
cellular response to external stimulusGO:007149620.023
endochondral bone growthGO:000341620.022
adherens junction organizationGO:003433240.022
regulation of lymphangiogenesisGO:190149040.022
positive regulation of leukocyte chemotaxisGO:000269010.022
rna biosynthetic processGO:00327741810.022
reproductionGO:0000003400.022
regulation of meiotic cell cycleGO:005144510.022
lymph vessel developmentGO:0001945270.022
regulation of cell cell adhesionGO:0022407130.022
carbohydrate derivative biosynthetic processGO:1901137430.022
multicellular organism reproductionGO:0032504350.022
positive regulation of protein polymerizationGO:003227320.022
positive regulation of protein complex assemblyGO:003133420.022
regulation of cell communicationGO:00106462320.022
sleepGO:003043110.022
gland developmentGO:00487321430.021
regulation of protein polymerizationGO:003227120.021
single organism localizationGO:19025782250.021
sensory organ developmentGO:00074233930.021
urogenital system developmentGO:0001655970.021
renal system processGO:0003014140.021
glomerular epithelium developmentGO:0072010120.021
er to golgi vesicle mediated transportGO:000688810.021
neuron projection extensionGO:1990138450.021
positive regulation of nucleic acid templated transcriptionGO:1903508570.021
glomerular epithelial cell fate commitmentGO:007231440.020
cellular lipid metabolic processGO:0044255360.020
protein targeting to nucleusGO:004474430.020
ovulation cycle processGO:002260220.020
cartilage developmentGO:0051216960.020
positive regulation of rna biosynthetic processGO:1902680570.020
carbohydrate derivative metabolic processGO:1901135610.020
carboxylic acid metabolic processGO:0019752220.019
cellular response to starvationGO:000926710.019
response to organic substanceGO:00100331530.019
protein localization to nucleusGO:003450430.019
regulation of protein metabolic processGO:0051246560.019
cell morphogenesis involved in differentiationGO:00009041950.019
guanosine containing compound catabolic processGO:190106920.019
mesoderm formationGO:0001707430.019
hormone transportGO:000991420.019
regulation of cell motilityGO:2000145460.019
regulation of gene expressionGO:00104682650.018
single organism organelle organizationGO:19025891990.018
anatomical structure arrangementGO:004853220.018
mitochondrion organizationGO:000700540.018
positive regulation of transcription dna templatedGO:0045893570.018
positive regulation of cellular amine metabolic processGO:003324000.018
cell agingGO:000756920.018
interspecies interaction between organismsGO:004441940.018
cell projection morphogenesisGO:00488582440.018
cytokinesisGO:000091030.018
organic acid metabolic processGO:0006082310.018
meiotic nuclear divisionGO:000712640.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.018
ceramide metabolic processGO:000667250.018
negative regulation of reproductive processGO:200024230.018
organelle organizationGO:00069962270.017
cellular protein metabolic processGO:00442671290.017
actin polymerization or depolymerizationGO:000815420.017
regulation of organ growthGO:004662030.017
regulation of signalingGO:00230512350.017
dendrite guidanceGO:007098300.017
stem cell proliferationGO:007208940.017
response to glucoseGO:000974930.017
adrenal gland developmentGO:0030325100.016
cell cell signalingGO:0007267520.016
cardiac muscle tissue developmentGO:0048738480.016
leukocyte proliferationGO:007066110.016
regulation of cell adhesionGO:0030155150.016
positive regulation of cell activationGO:005086710.016
eye photoreceptor cell differentiationGO:0001754450.016
myotube differentiationGO:0014902450.016
kidney epithelium developmentGO:0072073230.016
somatic muscle developmentGO:000752540.016
regulation of protein glycosylationGO:006004930.016
regulation of synaptic plasticityGO:004816710.016
compound eye developmentGO:004874920.016
hemopoiesisGO:00300971830.016
regulation of carbohydrate metabolic processGO:000610940.016
actin filament based processGO:0030029640.016
regulation of cell developmentGO:00602841000.015
sexual reproductionGO:0019953360.015
nephron morphogenesisGO:007202820.015
oxoacid metabolic processGO:0043436310.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015
intracellular signal transductionGO:0035556850.015
dicarboxylic acid transportGO:000683510.015
positive regulation of cell substrate adhesionGO:001081110.015
axon extensionGO:0048675450.015
gtp catabolic processGO:000618420.015
neutrophil migrationGO:1990266100.015
glycoprotein metabolic processGO:0009100230.015
peptidyl serine phosphorylationGO:001810510.015
leukocyte chemotaxisGO:0030595120.015
mononuclear cell proliferationGO:003294310.015
regulation of cell projection assemblyGO:006049140.014
response to nicotineGO:003509420.014
amine metabolic processGO:000930820.014
actin mediated cell contractionGO:007025210.014
cell projection assemblyGO:0030031640.014
morphogenesis of a branching epitheliumGO:0061138160.014
transcription from rna polymerase ii promoterGO:0006366800.014
positive regulation of signalingGO:0023056560.014
renal system developmentGO:0072001940.014
negative regulation of mapk cascadeGO:004340940.014
embryonic skeletal system developmentGO:0048706970.014
response to hypoxiaGO:0001666250.014
macromolecule modificationGO:00434121110.014
immune system processGO:00023762410.014
lymphocyte proliferationGO:004665110.014
regulation of ion transmembrane transporter activityGO:003241220.014
lateral line system developmentGO:0048925760.014
phagocytosisGO:000690930.014
convergent extension involved in organogenesisGO:0060029100.014
regulation of cysteine type endopeptidase activityGO:2000116210.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.014
regulation of cellular amino acid metabolic processGO:000652100.014
establishment of localizationGO:00512342440.014
hematopoietic or lymphoid organ developmentGO:00485341910.014
phosphorus metabolic processGO:00067931090.013
amino acid transportGO:000686520.013
negative regulation of catabolic processGO:000989530.013
lateral inhibitionGO:004633110.013
commissural neuron axon guidanceGO:007167930.013
regulation of production of molecular mediator of immune responseGO:000270010.013
positive regulation of cellular component movementGO:0051272110.013
transportGO:00068102200.013
negative regulation of macromolecule biosynthetic processGO:0010558480.013
protein modification processGO:00362111000.013
establishment of protein localization to organelleGO:007259440.013
neuron neuron synaptic transmissionGO:000727010.013
regulation of protein catabolic processGO:004217610.013
positive regulation of transportGO:005105020.013
regulation of nucleotide catabolic processGO:003081120.013
regulation of localizationGO:00328791040.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
developmental growth involved in morphogenesisGO:0060560860.013
neuron projection guidanceGO:0097485860.013
regulation of system processGO:0044057400.012
regulation of transmembrane transporter activityGO:002289820.012
muscle organ developmentGO:00075171010.012
cellular response to radiationGO:007147840.012
sensory system developmentGO:0048880760.012
kidney morphogenesisGO:0060993150.012
neural retina developmentGO:0003407490.012
cellular amine metabolic processGO:004410620.012
response to foodGO:003209410.012
cellular lipid catabolic processGO:004424230.012
regulation of neural precursor cell proliferationGO:200017730.012
neural tube formationGO:0001841160.012
positive regulation of macromolecule biosynthetic processGO:0010557590.012
chondrocyte developmentGO:000206340.012
positive regulation of cytoskeleton organizationGO:005149530.012
camera type eye developmentGO:00430102220.012
gliogenesisGO:0042063450.012
regulation of wnt signaling pathwayGO:0030111530.012
signal transduction by phosphorylationGO:0023014180.012
peptidyl threonine modificationGO:001821010.012
negative regulation of gene expressionGO:0010629650.012
neuron projection morphogenesisGO:00488121610.012
positive regulation of locomotionGO:0040017140.012
regulation of phospholipase activityGO:001051720.012
nerve developmentGO:0021675450.012
cellular amino acid metabolic processGO:000652070.012
cellular protein catabolic processGO:004425740.012
renal tubule morphogenesisGO:006133310.011
regenerationGO:0031099910.011
aromatic compound biosynthetic processGO:00194382170.011
nephron epithelium morphogenesisGO:007208810.011
regulation of molecular functionGO:0065009700.011
cellular response to extracellular stimulusGO:003166820.011
neural crest cell migrationGO:0001755420.011
fertilizationGO:000956630.011
eye morphogenesisGO:00485921440.011
lymphangiogenesisGO:0001946250.011
regulation of proteolysisGO:0030162240.011
proteolysisGO:0006508380.011
positive regulation of endothelial cell migrationGO:001059520.011
growth plate cartilage developmentGO:000341720.011
regulation of neuronal synaptic plasticityGO:004816810.011
protein glycosylationGO:000648690.011
regulation of stem cell proliferationGO:007209120.011
neuromuscular synaptic transmissionGO:000727420.011
actomyosin structure organizationGO:0031032530.011
single organism transportGO:00447652060.011
endocrine system developmentGO:0035270650.011
response to growth factorGO:0070848390.011
nuclear importGO:005117030.011
positive regulation of developmental processGO:0051094500.011
neural crest cell developmentGO:0014032620.011
cytoskeleton organizationGO:0007010960.011
positive regulation of lipid metabolic processGO:004583410.011
epibolyGO:0090504410.011
positive regulation of rna metabolic processGO:0051254590.010
bmp signaling pathwayGO:0030509520.010
negative regulation of protein serine threonine kinase activityGO:007190120.010
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.010
proteolysis involved in cellular protein catabolic processGO:005160330.010
b cell activationGO:004211320.010
determination of left right symmetryGO:00073681790.010
leukocyte migrationGO:0050900150.010
cytokine mediated signaling pathwayGO:001922170.010
adult behaviorGO:003053420.010
sex determinationGO:000753010.010
rhombomere formationGO:0021594120.010
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.010
neurological system processGO:0050877620.010
glycolipid biosynthetic processGO:000924710.010
regulation of dendrite developmentGO:005077330.010
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.010
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.010
deathGO:00162651210.010
positive regulation of catabolic processGO:000989640.010
g1 s transition of mitotic cell cycleGO:000008210.010
endocrine processGO:005088620.010
formation of primary germ layerGO:0001704620.010
positive regulation of multi organism processGO:004390230.010
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:000718750.010
regulation of nucleobase containing compound metabolic processGO:00192192500.010

plce1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.133
kidney diseaseDOID:55700.113
urinary system diseaseDOID:1800.113
disease of cellular proliferationDOID:1456600.066
cancerDOID:16200.066
organ system cancerDOID:005068600.056
muscle tissue diseaseDOID:6600.052
musculoskeletal system diseaseDOID:1700.052
muscular diseaseDOID:008000000.052
myopathyDOID:42300.052