Danio rerio

0 known processes

rheb

ras homolog enriched in brain

(Aliases: MGC153231,zgc:153231,im:7161941)

rheb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.101
agingGO:000756820.068
nitrogen compound metabolic processGO:00068073190.047
Human Fly
proteolysis involved in cellular protein catabolic processGO:005160330.045
cellular protein catabolic processGO:004425740.044
positive regulation of transportGO:005105020.043
nuclear transportGO:005116940.042
nucleocytoplasmic transportGO:000691340.041
gene expressionGO:00104672520.041
Human Fly
ubiquitin dependent protein catabolic processGO:000651130.040
establishment of protein localization to organelleGO:007259440.040
organic substance biosynthetic processGO:19015762890.039
Human Fly
cellular aromatic compound metabolic processGO:00067252950.039
Human Fly
negative regulation of biological processGO:00485193040.038
Fly
modification dependent protein catabolic processGO:001994130.038
meiotic nuclear divisionGO:000712640.037
cellular macromolecule metabolic processGO:00442603910.037
Human Fly
cellular nitrogen compound metabolic processGO:00346412900.036
Human Fly
maintenance of locationGO:005123540.035
modification dependent macromolecule catabolic processGO:004363230.035
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.035
proteasomal protein catabolic processGO:001049820.034
protein localization to nucleusGO:003450430.033
positive regulation of cell cycleGO:004578730.033
organic cyclic compound metabolic processGO:19013603010.032
Human Fly
negative regulation of protein phosphorylationGO:000193340.032
regulation of metabolic processGO:00192223590.031
Human Fly
regulation of macromolecule metabolic processGO:00602553170.031
Human Fly
nucleic acid metabolic processGO:00903042440.031
Human
regulation of multicellular organism growthGO:004001440.031
nucleobase containing compound metabolic processGO:00061392740.031
Human Fly
single organism nuclear importGO:190259330.030
regulation of protein transportGO:005122330.030
cognitionGO:005089010.030
heterocycle metabolic processGO:00464832900.030
Human Fly
phagocytosisGO:000690930.030
mitochondrion organizationGO:000700540.030
protein importGO:001703830.030
regulation of protein localization to nucleusGO:190018020.029
multicellular organism growthGO:003526440.029
Fly
regulation of cellular metabolic processGO:00313233200.029
Human Fly
regulation of cytokine productionGO:000181730.029
regulation of nucleocytoplasmic transportGO:004682220.028
stem cell maintenanceGO:001982740.028
autophagyGO:000691440.028
Fly
amine metabolic processGO:000930820.028
protein acetylationGO:000647320.028
regulation of establishment of protein localizationGO:007020140.028
protein import into nucleusGO:000660630.028
protein targeting to nucleusGO:004474430.028
nuclear importGO:005117030.027
positive regulation of catabolic processGO:000989640.027
lipid storageGO:001991510.027
cellular amine metabolic processGO:004410620.026
i kappab kinase nf kappab signalingGO:000724940.026
cellular response to external stimulusGO:007149620.026
regulation of intracellular protein transportGO:003315730.026
response to stressGO:00069502630.026
Fly
regulation of cytoplasmic transportGO:190364940.025
cellular response to nutrient levelsGO:003166920.025
regulation of meiotic cell cycleGO:005144510.025
protein metabolic processGO:00195381830.025
Fly
tube morphogenesisGO:00352393490.025
regulation of protein import into nucleusGO:004230620.025
regulation of protein targetingGO:190353320.025
regulation of i kappab kinase nf kappab signalingGO:004312240.025
regulation of autophagyGO:001050630.025
Fly
gtp metabolic processGO:004603940.024
Fly
regulation of nitrogen compound metabolic processGO:00511712510.024
Human
negative regulation of cellular processGO:00485232830.024
Fly
extrinsic apoptotic signaling pathwayGO:009719130.024
regulation of gene expressionGO:00104682650.024
Human Fly
cytokinesisGO:000091030.024
signal transductionGO:00071654550.024
Human Fly
cellular biosynthetic processGO:00442492860.024
Human Fly
peptidyl lysine acetylationGO:001839420.024
rna metabolic processGO:00160702190.024
Human
regulation of mrna processingGO:005068430.023
compound eye developmentGO:004874920.023
guanosine containing compound metabolic processGO:190106840.023
Fly
rna localizationGO:000640340.023
heterocycle biosynthetic processGO:00181302150.023
Human
regulation of protein catabolic processGO:004217610.023
ribonucleoside monophosphate catabolic processGO:000915840.023
morphogenesis of an epitheliumGO:00020093330.023
single organism metabolic processGO:00447102170.023
Fly
meiotic cell cycle processGO:190304630.023
response to monosaccharideGO:003428430.022
organelle organizationGO:00069962270.022
regulation of cellular biosynthetic processGO:00313262450.022
Human Fly
membrane fusionGO:006102520.022
cell surface receptor signaling pathwayGO:00071663250.022
internal protein amino acid acetylationGO:000647520.022
gtp catabolic processGO:000618420.022
Fly
regulation of cellular amino acid metabolic processGO:000652100.022
female sex differentiationGO:004666040.022
positive regulation of cellular catabolic processGO:003133130.022
regulation of protein modification by small protein conjugation or removalGO:190332030.022
regulation of primary metabolic processGO:00800903110.021
Human Fly
neuron differentiationGO:00301823530.021
Fly
protein acylationGO:004354330.021
regulation of protein ubiquitinationGO:003139630.021
guanosine containing compound catabolic processGO:190106920.021
Fly
aromatic compound biosynthetic processGO:00194382170.021
Human
positive regulation of cellular component biogenesisGO:004408930.021
Fly
biosynthetic processGO:00090582940.021
Human Fly
regulation of cell shapeGO:000836010.021
regulation of developmental processGO:00507932470.021
regulation of mrna splicing via spliceosomeGO:004802430.021
sensory organ developmentGO:00074233930.021
internal peptidyl lysine acetylationGO:001839320.021
regulation of cellular amine metabolic processGO:003323800.021
regulation of cell activationGO:005086510.021
regulation of multicellular organismal processGO:00512392770.021
organic acid metabolic processGO:0006082310.020
cellular response to extracellular stimulusGO:003166820.020
regulation of cellular ketone metabolic processGO:001056570.020
regulation of nucleobase containing compound metabolic processGO:00192192500.020
Human
positive regulation of biological processGO:00485182530.020
Human Fly
cell substrate adhesionGO:003158940.020
nuclear exportGO:005116810.020
leukocyte proliferationGO:007066110.020
macromolecule biosynthetic processGO:00090592270.020
Human Fly
atp catabolic processGO:000620040.020
organonitrogen compound metabolic processGO:1901564740.020
Fly
cellular component morphogenesisGO:00329893360.020
Fly
regulation of metal ion transportGO:001095940.020
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.020
female gonad developmentGO:000858540.020
single fertilizationGO:000733830.020
cellular nitrogen compound biosynthetic processGO:00442712180.020
Human
regulation of signalingGO:00230512350.020
Fly
stem cell proliferationGO:007208940.019
organic cyclic compound biosynthetic processGO:19013622230.019
Human
regulation of cellular protein catabolic processGO:190336210.019
single organism membrane fusionGO:004480120.019
oxoacid metabolic processGO:0043436310.019
carboxylic acid catabolic processGO:004639530.019
regulation of neural precursor cell proliferationGO:200017730.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.019
regulation of bindingGO:005109830.019
regulation of protein complex assemblyGO:004325430.019
protein polyubiquitinationGO:000020940.019
carboxylic acid metabolic processGO:0019752220.019
cellular ketone metabolic processGO:0042180110.019
response to drugGO:004249330.019
antimicrobial humoral responseGO:001973020.019
organelle fusionGO:004828430.019
regulation of reproductive processGO:200024140.019
cellular amino acid metabolic processGO:000652070.019
cell projection morphogenesisGO:00488582440.019
Fly
cell part morphogenesisGO:00329902460.019
Fly
response to hexoseGO:000974630.019
cellular protein metabolic processGO:00442671290.019
Fly
eye developmentGO:00016542770.019
purine ribonucleoside monophosphate catabolic processGO:000916940.019
regulation of biological qualityGO:00650082630.019
Fly
regulation of signal transductionGO:00099662250.018
Fly
cellular response to biotic stimulusGO:007121630.018
small molecule catabolic processGO:004428230.018
negative regulation of protein kinase activityGO:000646940.018
regulation of synapse organizationGO:005080730.018
primary neural tube formationGO:001402010.018
immune system processGO:00023762410.018
positive regulation of immune effector processGO:000269930.018
mitotic dna integrity checkpointGO:004477440.018
cellular response to lipopolysaccharideGO:007122230.018
negative regulation of kinase activityGO:003367340.018
cellular response to starvationGO:000926710.018
regulation of rna metabolic processGO:00512522240.018
Human
mononuclear cell proliferationGO:003294310.018
exocytosisGO:000688710.018
response to chemicalGO:00422213200.018
Fly
erk1 and erk2 cascadeGO:007037140.018
positive regulation of dna metabolic processGO:005105410.018
cell morphogenesisGO:00009022890.018
Fly
digestive system developmentGO:00551232890.018
cellular macromolecule biosynthetic processGO:00346452240.018
Human Fly
positive regulation of cell activationGO:005086710.018
regulation of multicellular organismal developmentGO:20000262230.017
regulation of cell communicationGO:00106462320.017
Fly
fertilizationGO:000956630.017
production of molecular mediator of immune responseGO:000244020.017
positive regulation of jnk cascadeGO:004633030.017
positive regulation of i kappab kinase nf kappab signalingGO:004312330.017
regulation of nucleotide catabolic processGO:003081120.017
nucleoside monophosphate catabolic processGO:000912540.017
response to glucoseGO:000974930.017
b cell activationGO:004211320.017
regulation of nucleoside metabolic processGO:000911820.017
cellular amide metabolic processGO:004360340.017
regulation of response to stimulusGO:00485832690.017
Fly
secondary metabolic processGO:001974830.017
central nervous system developmentGO:00074173870.017
regulation of biosynthetic processGO:00098892500.017
Human Fly
localization of cellGO:00516742440.017
cellular component movementGO:00069283350.017
Fly
endosomal transportGO:001619720.017
Yeast
meiotic chromosome segregationGO:004513230.017
embryo development ending in birth or egg hatchingGO:00097922710.017
regulation of production of molecular mediator of immune responseGO:000270010.017
rna biosynthetic processGO:00327741810.017
Human
negative regulation of catabolic processGO:000989530.017
Fly
single organism organelle organizationGO:19025891990.017
lymphocyte proliferationGO:004665110.017
positive regulation of secretionGO:005104710.016
digestive tract morphogenesisGO:00485462310.016
synaptic growth at neuromuscular junctionGO:005112420.016
Fly
symbiosis encompassing mutualism through parasitismGO:004440340.016
response to uvGO:000941130.016
mitotic dna damage checkpointGO:004477340.016
regulation of alternative mrna splicing via spliceosomeGO:000038110.016
generation of neuronsGO:00486993850.016
Fly
tissue remodelingGO:004877140.016
nucleic acid templated transcriptionGO:00976591810.016
Human
cellular component assemblyGO:00226071700.016
Fly
positive regulation of protein complex assemblyGO:003133420.016
regulation of dna replicationGO:000627530.016
neuron developmentGO:00486662620.016
Fly
positive regulation of cellular amine metabolic processGO:003324000.016
locomotionGO:00400113130.016
Fly
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.016
intracellular mrna localizationGO:000829810.016
negative regulation of nuclear divisionGO:005178430.016
peptide transportGO:001583310.016
rna modificationGO:000945120.016
regulation of purine nucleotide catabolic processGO:003312120.016
regulation of synapse assemblyGO:005196330.016
establishment of localizationGO:00512342440.016
Yeast
negative regulation of mapk cascadeGO:004340940.016
spermatid developmentGO:000728620.016
cell migrationGO:00164772370.016
single organism transportGO:00447652060.016
Yeast
peptidyl serine phosphorylationGO:001810510.016
cell matrix adhesionGO:000716040.016
positive regulation of cytokine productionGO:000181920.016
cellular component disassemblyGO:002241110.016
cellular response to chemical stimulusGO:00708871570.015
regulation of gtp catabolic processGO:003312420.015
cellular response to molecule of bacterial originGO:007121930.015
negative regulation of cytokine productionGO:000181810.015
cytoskeleton dependent cytokinesisGO:006164030.015
cellular response to oxygen levelsGO:007145310.015
blood vessel developmentGO:00015682460.015
developmental programmed cell deathGO:001062340.015
transcription dna templatedGO:00063511810.015
Human
negative regulation of protein transportGO:005122430.015
gastrulationGO:00073692080.015
glucose homeostasisGO:004259310.015
regulation of cellular macromolecule biosynthetic processGO:20001122220.015
Human Fly
regulation of macromolecule biosynthetic processGO:00105562250.015
Human Fly
double strand break repair via homologous recombinationGO:000072410.015
blood vessel morphogenesisGO:00485142160.015
nucleic acid transportGO:005065720.015
regulation of erk1 and erk2 cascadeGO:007037240.015
regulation of nucleic acid templated transcriptionGO:19035062130.015
Human
small molecule metabolic processGO:0044281770.015
Fly
development of primary female sexual characteristicsGO:004654540.015
cell motilityGO:00488702440.015
regionalizationGO:00030022740.015
phagocytosis engulfmentGO:000691110.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
vasculature developmentGO:00019442780.015
alternative mrna splicing via spliceosomeGO:000038010.015
adult behaviorGO:003053420.015
membrane invaginationGO:001032410.015
protein localization to plasma membraneGO:007265910.015
organic acid catabolic processGO:001605430.015
cell projection organizationGO:00300302840.015
Fly
cellular component biogenesisGO:00440851780.015
Fly
interspecies interaction between organismsGO:004441940.014
adherens junction organizationGO:003433240.014
regulation of dendrite developmentGO:005077330.014
rna transportGO:005065820.014
negative regulation of cellular catabolic processGO:003133030.014
Fly
positive regulation of erk1 and erk2 cascadeGO:007037420.014
cellular carbohydrate metabolic processGO:004426240.014
g2 dna damage checkpointGO:003157230.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
camera type eye developmentGO:00430102220.014
regulation of gtpase activityGO:004308720.014
positive regulation of stress activated mapk cascadeGO:003287430.014
positive regulation of secretion by cellGO:190353210.014
head developmentGO:00603223030.014
tube closureGO:006060610.014
carbohydrate homeostasisGO:003350010.014
protein heterooligomerizationGO:005129110.014
protein secretionGO:000930610.014
spermatid differentiationGO:004851520.014
regulation of response to biotic stimulusGO:000283120.014
sleepGO:003043110.014
lipid catabolic processGO:001604240.014
positive regulation of chromosome organizationGO:200125210.014
transcription from rna polymerase ii promoterGO:0006366800.014
positive regulation of nucleoside metabolic processGO:004597910.014
transportGO:00068102200.014
Yeast
response to external stimulusGO:00096052640.014
Fly
positive regulation of lymphocyte mediated immunityGO:000270810.014
lateral inhibitionGO:004633110.014
macromolecule modificationGO:00434121110.014
dna templated transcription elongationGO:000635430.014
nucleobase containing compound biosynthetic processGO:00346542050.014
Human
locomotor rhythmGO:004547530.014
neuron neuron synaptic transmissionGO:000727010.014
negative regulation of cytoplasmic transportGO:190365020.014
peptidyl serine modificationGO:001820920.014
peptide metabolic processGO:000651810.014
negative regulation of metabolic processGO:0009892860.014
Fly
positive regulation of cellular processGO:00485222010.014
Fly
hemopoiesisGO:00300971830.013
stem cell divisionGO:001714510.013
regulation of stem cell proliferationGO:007209120.013
response to organic substanceGO:00100331530.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
mitochondrial transportGO:000683920.013
sequestering of calcium ionGO:005120830.013
protein polymerizationGO:005125840.013
cellular response to radiationGO:007147840.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
transcription elongation from rna polymerase ii promoterGO:000636830.013
rna 3 end processingGO:003112320.013
centrosome cycleGO:000709810.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.013
positive regulation of map kinase activityGO:004340630.013
centrosome duplicationGO:005129810.013
regulation of rna biosynthetic processGO:20011412130.013
Human
cell cycle g1 s phase transitionGO:004484310.013
Fly
determination of left right symmetryGO:00073681790.013
embryonic organ developmentGO:00485683810.013
positive regulation of gtp catabolic processGO:003312610.013
dorsal ventral pattern formationGO:00099531250.013
positive regulation of nucleotide catabolic processGO:003081310.013
cellular response to decreased oxygen levelsGO:003629410.013
intracellular signal transductionGO:0035556850.013
Human Fly
chemosensory behaviorGO:000763510.013
signal transduction in absence of ligandGO:003803410.013
retina development in camera type eyeGO:00600411460.013
regulation of calcium ion transportGO:005192420.013
regulation of transporter activityGO:003240920.013
chordate embryonic developmentGO:00430092710.013
neuroblast proliferationGO:000740520.013
heart developmentGO:00075073130.013
g1 s transition of mitotic cell cycleGO:000008210.013
Fly
negative regulation of protein serine threonine kinase activityGO:007190120.013
response to nutrientGO:000758430.013
protein dephosphorylationGO:000647030.013
sequestering of metal ionGO:005123830.013
positive regulation of chromatin modificationGO:190331010.013
protein stabilizationGO:005082120.013
somatic muscle developmentGO:000752540.012
system processGO:00030081850.012
protein complex disassemblyGO:004324110.012
specification of symmetryGO:00097992040.012
post embryonic organ developmentGO:004856940.012
negative regulation of protein localization to nucleusGO:190018120.012
positive regulation of cytoskeleton organizationGO:005149530.012
purine nucleoside monophosphate catabolic processGO:000912840.012
single organism localizationGO:19025782250.012
Yeast
vacuolar transportGO:000703420.012
cell cycleGO:0007049930.012
Fly
regulation of inflammatory responseGO:005072720.012
regulation of synaptic plasticityGO:004816710.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
convergent extensionGO:00600261180.012
multi organism processGO:00517041340.012
toll like receptor signaling pathwayGO:000222440.012
negative regulation of secretionGO:005104820.012
golgi vesicle transportGO:004819330.012
multi organism cellular processGO:004476420.012
angiogenesisGO:00015251580.012
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
positive regulation of small gtpase mediated signal transductionGO:005105710.012
homeostatic processGO:00425921420.012
establishment of rna localizationGO:005123630.012
regulation of neurotransmitter transportGO:005158810.012
regulation of dna templated transcription elongationGO:003278430.012
negative regulation of small gtpase mediated signal transductionGO:005105810.012
somatic stem cell maintenanceGO:003501910.012
negative regulation of sequestering of calcium ionGO:005128340.012
regulation of chromosome segregationGO:005198310.012
neurotransmitter transportGO:000683620.012
regulation of organ growthGO:004662030.012
regulation of stem cell differentiationGO:200073640.012
protein homooligomerizationGO:005126030.012
macroautophagyGO:001623610.012
regulation of transcription dna templatedGO:00063552130.012
Human
muscle structure developmentGO:00610611960.012
regulation of sequestering of calcium ionGO:005128240.012
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.012
negative regulation of cell communicationGO:0010648960.012
nucleobase containing compound transportGO:001593120.012
negative regulation of stem cell differentiationGO:200073720.011
cellular lipid catabolic processGO:004424230.011
response to corticosteroidGO:003196010.011
response to carbohydrateGO:000974330.011
positive regulation of translationGO:004572710.011
Fly
cellular response to light stimulusGO:007148240.011
negative regulation of intracellular transportGO:003238730.011
rna export from nucleusGO:000640510.011
cell morphogenesis involved in differentiationGO:00009041950.011
Fly
positive regulation of cell divisionGO:005178120.011
digestive tract developmentGO:00485652650.011
mitotic g2 m transition checkpointGO:004481830.011
cellular response to hypoxiaGO:007145610.011
cellular protein modification processGO:00064641000.011
phosphate containing compound metabolic processGO:00067961080.011
Fly
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
positive regulation of canonical wnt signaling pathwayGO:009026340.011
mitotic g2 dna damage checkpointGO:000709530.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
negative regulation of secretion by cellGO:190353120.011
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.011
negative regulation of defense responseGO:003134820.011
phosphorus metabolic processGO:00067931090.011
Fly
brain developmentGO:00074202930.011
mitotic cytokinesisGO:000028130.011
peptidyl threonine phosphorylationGO:001810710.011
ovulation cycle processGO:002260220.011
negative regulation of protein import into nucleusGO:004230820.011
regulation of blood pressureGO:000821710.011
viral processGO:001603210.011
osteoclast differentiationGO:003031610.011
negative regulation of signal transductionGO:0009968940.011
growthGO:00400071740.011
Fly
positive regulation of gtpase activityGO:004354710.011
monocarboxylic acid catabolic processGO:007232930.011
multicellular organismal metabolic processGO:004423620.011
negative regulation of intracellular protein transportGO:009031730.011
regulation of jak stat cascadeGO:004642530.011
regulation of rho protein signal transductionGO:003502320.011
translational initiationGO:000641330.011
cytoplasm organizationGO:000702840.011
cell substrate junction assemblyGO:000704420.011
double strand break repairGO:000630230.011
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.011
negative regulation of ras protein signal transductionGO:004658010.011
cytosolic calcium ion transportGO:006040130.011
epithelial tube morphogenesisGO:00605621480.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
negative regulation of signalingGO:0023057960.011
negative regulation of response to stimulusGO:00485851040.011
lipid homeostasisGO:005508830.011
somite developmentGO:0061053960.011
germ line stem cell maintenanceGO:003071820.011
regulation of cell substrate adhesionGO:001081010.011
lipid oxidationGO:003444010.011
meiosis iGO:000712710.011
cellular respirationGO:004533330.011
positive regulation of multi organism processGO:004390230.010
cell deathGO:00082191210.010
protein modification processGO:00362111000.010
anterior posterior pattern specificationGO:00099521520.010
phosphatidylinositol mediated signalingGO:004801520.010
macromolecular complex disassemblyGO:003298410.010
regulation of dendrite morphogenesisGO:004881430.010
release of sequestered calcium ion into cytosolGO:005120930.010
negative regulation of map kinase activityGO:004340720.010
negative regulation of multi organism processGO:004390130.010
fatty acid catabolic processGO:000906210.010
rna polyadenylationGO:004363120.010
positive regulation of cell adhesionGO:004578510.010
negative regulation of mitosisGO:004583930.010
sensory organ morphogenesisGO:00905962000.010
positive regulation of histone modificationGO:003105810.010
b cell differentiationGO:003018310.010
determination of bilateral symmetryGO:00098552040.010
negative regulation of translationGO:001714810.010
developmental growthGO:00485891660.010
Fly
regulation of anatomical structure morphogenesisGO:00226031300.010
actin filament polymerizationGO:003004120.010
muscle cell differentiationGO:00426921390.010
ovulation cycleGO:004269820.010
organism emergence from protective structureGO:007168440.010
positive regulation of neuron apoptotic processGO:004352510.010

rheb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
nervous system diseaseDOID:86300.023
cancerDOID:16200.020
disease of cellular proliferationDOID:1456600.020
musculoskeletal system diseaseDOID:1700.020
inherited metabolic disorderDOID:65500.019
disease of metabolismDOID:001466700.019
organ system cancerDOID:005068600.014
immune system diseaseDOID:291400.012
connective tissue diseaseDOID:6500.012
muscle tissue diseaseDOID:6600.012
muscular diseaseDOID:008000000.012
myopathyDOID:42300.011
cardiovascular system diseaseDOID:128700.010
heart diseaseDOID:11400.010
cardiomyopathyDOID:005070000.010