Danio rerio

0 known processes

itk

IL2-inducible T-cell kinase

(Aliases: tec,Ptk)

itk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
aromatic compound biosynthetic processGO:00194382170.115
phagocytosisGO:000690930.106
organic cyclic compound metabolic processGO:19013603010.095
cellular component morphogenesisGO:00329893360.092
larval developmentGO:000216420.087
regulation of nitrogen compound metabolic processGO:00511712510.085
cellular nitrogen compound metabolic processGO:00346412900.085
maintenance of locationGO:005123540.083
organic cyclic compound biosynthetic processGO:19013622230.080
chordate embryonic developmentGO:00430092710.077
positive regulation of transportGO:005105020.077
stem cell proliferationGO:007208940.076
cellular aromatic compound metabolic processGO:00067252950.076
digestive system developmentGO:00551232890.075
rna biosynthetic processGO:00327741810.070
regulation of nucleobase containing compound metabolic processGO:00192192500.068
embryo development ending in birth or egg hatchingGO:00097922710.068
hormone transportGO:000991420.068
cellular macromolecule metabolic processGO:00442603910.068
cellular component movementGO:00069283350.066
heterocycle metabolic processGO:00464832900.066
transportGO:00068102200.065
heterocycle biosynthetic processGO:00181302150.062
regulation of rna biosynthetic processGO:20011412130.062
nucleic acid metabolic processGO:00903042440.062
regulation of cellular biosynthetic processGO:00313262450.062
brain developmentGO:00074202930.061
response to chemicalGO:00422213200.061
single organism localizationGO:19025782250.061
digestive tract developmentGO:00485652650.060
nucleobase containing compound biosynthetic processGO:00346542050.059
blood vessel developmentGO:00015682460.058
regionalizationGO:00030022740.057
blood vessel morphogenesisGO:00485142160.057
rna metabolic processGO:00160702190.056
head developmentGO:00603223030.056
regulation of biosynthetic processGO:00098892500.056
biosynthetic processGO:00090582940.056
immune system processGO:00023762410.056
nitrogen compound metabolic processGO:00068073190.056
establishment of localizationGO:00512342440.056
regulation of gene expressionGO:00104682650.055
regulation of rna metabolic processGO:00512522240.054
nuclear transportGO:005116940.053
embryonic organ developmentGO:00485683810.052
agingGO:000756820.051
tissue remodelingGO:004877140.050
positive regulation of cellular processGO:00485222010.050
protein localization to nucleusGO:003450430.049
regulation of developmental processGO:00507932470.047
locomotionGO:00400113130.046
positive regulation of cytosolic calcium ion concentrationGO:000720440.046
sensory perception of chemical stimulusGO:000760630.046
regulation of cell shapeGO:000836010.046
response to external stimulusGO:00096052640.046
vasculature developmentGO:00019442780.045
transcription dna templatedGO:00063511810.045
single organism transportGO:00447652060.045
nucleobase containing compound metabolic processGO:00061392740.044
positive regulation of nucleobase containing compound metabolic processGO:0045935690.043
cellular biosynthetic processGO:00442492860.043
signal transductionGO:00071654550.043
negative regulation of biological processGO:00485193040.042
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.042
regulation of macromolecule metabolic processGO:00602553170.041
heart developmentGO:00075073130.041
regulation of signalingGO:00230512350.041
regulation of cytokine productionGO:000181730.041
organic acid metabolic processGO:0006082310.040
immune system developmentGO:00025201910.040
cell motilityGO:00488702440.040
regulation of primary metabolic processGO:00800903110.040
myofibril assemblyGO:0030239480.039
regulation of circadian rhythmGO:004275240.039
somitogenesisGO:0001756870.039
cell surface receptor signaling pathwayGO:00071663250.039
gene expressionGO:00104672520.038
dorsal ventral pattern formationGO:00099531250.038
cellular nitrogen compound biosynthetic processGO:00442712180.038
multicellular organism growthGO:003526440.038
ameboidal type cell migrationGO:00016671430.037
metal ion transportGO:0030001580.037
regulation of cellular macromolecule biosynthetic processGO:20001122220.037
somite developmentGO:0061053960.036
regulation of cellular metabolic processGO:00313233200.036
peptide transportGO:001583310.036
regulation of macromolecule biosynthetic processGO:00105562250.036
regulation of metabolic processGO:00192223590.035
proteolysis involved in cellular protein catabolic processGO:005160330.035
gastrulationGO:00073692080.035
response to organic substanceGO:00100331530.034
regulation of cell communicationGO:00106462320.034
tube morphogenesisGO:00352393490.034
regulation of hormone secretionGO:004688320.034
regulation of nucleic acid templated transcriptionGO:19035062130.033
nucleic acid templated transcriptionGO:00976591810.033
regulation of reactive oxygen species metabolic processGO:200037720.033
positive regulation of biological processGO:00485182530.033
hormone secretionGO:004687920.033
growthGO:00400071740.033
determination of bilateral symmetryGO:00098552040.033
b cell activationGO:004211320.032
regulation of localizationGO:00328791040.032
response to stressGO:00069502630.032
symbiosis encompassing mutualism through parasitismGO:004440340.032
regulation of cell activationGO:005086510.032
sensory organ developmentGO:00074233930.032
macromolecule biosynthetic processGO:00090592270.031
regulation of multicellular organismal processGO:00512392770.031
regulation of response to stimulusGO:00485832690.031
convergent extensionGO:00600261180.031
cellular macromolecule biosynthetic processGO:00346452240.030
segmentationGO:0035282970.030
hemopoiesisGO:00300971830.030
sensory system developmentGO:0048880760.030
lipid storageGO:001991510.029
angiogenesisGO:00015251580.029
adherens junction organizationGO:003433240.029
regulation of anatomical structure morphogenesisGO:00226031300.029
extrinsic apoptotic signaling pathwayGO:009719130.029
negative regulation of cellular processGO:00485232830.029
hematopoietic or lymphoid organ developmentGO:00485341910.029
oxoacid metabolic processGO:0043436310.029
positive regulation of secretion by cellGO:190353210.029
response to xenobiotic stimulusGO:0009410450.028
leukocyte proliferationGO:007066110.028
ear developmentGO:00435831270.028
regulation of transcription dna templatedGO:00063552130.028
mononuclear cell proliferationGO:003294310.028
skeletal system developmentGO:00015011810.028
cell migration involved in gastrulationGO:0042074790.028
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.028
regulation of cytoplasmic transportGO:190364940.028
digestive tract morphogenesisGO:00485462310.028
cellular component biogenesisGO:00440851780.028
cellular ketone metabolic processGO:0042180110.027
regulation of stem cell proliferationGO:007209120.027
ubiquitin dependent protein catabolic processGO:000651130.027
neuron developmentGO:00486662620.027
regulation of establishment of protein localizationGO:007020140.027
protein acetylationGO:000647320.027
cellular amine metabolic processGO:004410620.027
regulation of metal ion transportGO:001095940.027
positive regulation of map kinase activityGO:004340630.026
regulation of transcription from rna polymerase ii promoterGO:00063571140.026
generation of neuronsGO:00486993850.026
sequestering of metal ionGO:005123830.026
morphogenesis of an epitheliumGO:00020093330.026
positive regulation of rna biosynthetic processGO:1902680570.026
protein importGO:001703830.026
sensory organ morphogenesisGO:00905962000.026
organonitrogen compound metabolic processGO:1901564740.026
cell migrationGO:00164772370.026
cellular amino acid metabolic processGO:000652070.026
negative regulation of macromolecule metabolic processGO:0010605760.026
central nervous system developmentGO:00074173870.025
positive regulation of translationGO:004572710.025
cell fate commitmentGO:0045165990.025
positive regulation of cytokine productionGO:000181920.025
regulation of blood vessel sizeGO:005088020.025
protein import into nucleusGO:000660630.025
negative regulation of cellular metabolic processGO:0031324770.025
epithelial cell differentiationGO:00308551160.025
peptidyl lysine acetylationGO:001839420.025
neuromast developmentGO:0048884460.025
organic substance biosynthetic processGO:19015762890.024
positive regulation of catabolic processGO:000989640.024
b cell differentiationGO:003018310.024
neuron differentiationGO:00301823530.024
phagocytosis engulfmentGO:000691110.024
proteasomal protein catabolic processGO:001049820.024
muscle cell developmentGO:00550011150.024
cell projection morphogenesisGO:00488582440.024
amine metabolic processGO:000930820.023
positive regulation of immune effector processGO:000269930.023
positive regulation of metabolic processGO:00098931080.023
cell proliferationGO:0008283800.023
transcription from rna polymerase ii promoterGO:0006366800.023
nucleocytoplasmic transportGO:000691340.023
positive regulation of leukocyte differentiationGO:190210710.023
developmental growthGO:00485891660.023
translational initiationGO:000641330.023
regulation of biological qualityGO:00650082630.023
positive regulation of rna metabolic processGO:0051254590.023
eye developmentGO:00016542770.023
positive regulation of secretionGO:005104710.023
gastrulation with mouth forming secondGO:0001702440.023
muscle tissue developmentGO:00605371100.023
single organism nuclear importGO:190259330.022
interspecies interaction between organismsGO:004441940.022
cellular response to chemical stimulusGO:00708871570.022
regulation of apoptotic processGO:0042981980.022
muscle structure developmentGO:00610611960.022
positive regulation of nitrogen compound metabolic processGO:0051173690.022
small molecule metabolic processGO:0044281770.022
anterior posterior pattern specificationGO:00099521520.022
gland developmentGO:00487321430.022
protein targeting to nucleusGO:004474430.022
positive regulation of cell activationGO:005086710.022
inner ear developmentGO:00488391260.021
negative regulation of cytokine productionGO:000181810.021
protein acylationGO:004354330.021
homeostatic processGO:00425921420.021
striated muscle tissue developmentGO:00147061100.021
glucose importGO:004632320.021
cellular modified amino acid metabolic processGO:000657530.021
positive regulation of cellular biosynthetic processGO:0031328680.021
regulation of protein localization to nucleusGO:190018020.021
regulation of cell proliferationGO:0042127370.021
carboxylic acid metabolic processGO:0019752220.021
epithelial tube morphogenesisGO:00605621480.021
autophagyGO:000691440.021
morphogenesis of an epithelial sheetGO:0002011490.021
cellular component assemblyGO:00226071700.021
regulation of signal transductionGO:00099662250.021
specification of symmetryGO:00097992040.020
modification dependent macromolecule catabolic processGO:004363230.020
negative regulation of protein phosphorylationGO:000193340.020
activation of mapk activityGO:000018730.020
striated muscle cell developmentGO:00550021080.020
production of molecular mediator of immune responseGO:000244020.020
regulation of tube sizeGO:003515020.020
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.020
positive regulation of cellular component biogenesisGO:004408930.020
internal protein amino acid acetylationGO:000647520.020
establishment of protein localization to organelleGO:007259440.020
membrane invaginationGO:001032410.020
taxisGO:00423301090.020
skeletal muscle organ developmentGO:0060538780.020
lateral line system developmentGO:0048925760.020
regulation of extrinsic apoptotic signaling pathwayGO:200123630.020
positive regulation of biosynthetic processGO:0009891680.020
synaptic growth at neuromuscular junctionGO:005112420.019
regulation of wound healingGO:006104120.019
cell morphogenesisGO:00009022890.019
internal peptidyl lysine acetylationGO:001839320.019
protein metabolic processGO:00195381830.019
cellular localizationGO:0051641970.019
detection of chemical stimulusGO:000959340.019
organelle assemblyGO:00709251100.019
regulation of protein transportGO:005122330.019
cellular component assembly involved in morphogenesisGO:00109271070.019
regulation of stem cell differentiationGO:200073640.019
positive regulation of cellular metabolic processGO:0031325940.019
regulation of synapse assemblyGO:005196330.019
response to abiotic stimulusGO:00096281220.019
embryonic organ morphogenesisGO:00485622740.018
regulation of protein complex assemblyGO:004325430.018
positive regulation of gene expressionGO:0010628710.018
stem cell maintenanceGO:001982740.018
system processGO:00030081850.018
response to carbohydrateGO:000974330.018
positive regulation of muscle organ developmentGO:004863610.018
positive regulation of macromolecule biosynthetic processGO:0010557590.018
positive regulation of leukocyte mediated cytotoxicityGO:000191210.018
regulation of skeletal muscle tissue developmentGO:004864140.018
multi organism cellular processGO:004476420.018
protein secretionGO:000930610.018
determination of dorsal ventral asymmetryGO:0048262340.018
negative regulation of biosynthetic processGO:0009890550.018
negative regulation of nitrogen compound metabolic processGO:0051172590.018
meiotic nuclear divisionGO:000712640.018
positive regulation of chromatin modificationGO:190331010.018
neuroblast proliferationGO:000740520.018
endocrine system developmentGO:0035270650.018
female sex differentiationGO:004666040.018
viral processGO:001603210.017
regulation of multicellular organismal developmentGO:20000262230.017
regulation of cellular amine metabolic processGO:003323800.017
cellular protein catabolic processGO:004425740.017
embryonic heart tube morphogenesisGO:00031431080.017
modification dependent protein catabolic processGO:001994130.017
leukocyte mediated cytotoxicityGO:000190910.017
regulation of cellular amino acid metabolic processGO:000652100.017
regulation of synaptic plasticityGO:004816710.017
positive regulation of cell killingGO:003134320.017
regulation of multicellular organism growthGO:004001440.017
sequestering of calcium ionGO:005120830.017
pancreas developmentGO:0031016840.017
regulation of muscle contractionGO:000693730.017
regulation of inflammatory responseGO:005072720.017
neuron projection morphogenesisGO:00488121610.017
regulation of translational initiationGO:000644610.017
mesoderm developmentGO:0007498880.017
lymphocyte proliferationGO:004665110.017
mesoderm morphogenesisGO:0048332510.017
neurotransmitter secretionGO:000726920.017
positive regulation of multicellular organismal processGO:0051240520.016
cell killingGO:000190620.016
defense response to other organismGO:0098542330.016
organism emergence from protective structureGO:007168440.016
neuromuscular synaptic transmissionGO:000727420.016
positive regulation of leukocyte migrationGO:000268720.016
meiotic cell cycle processGO:190304630.016
membrane repolarizationGO:008600920.016
response to monosaccharideGO:003428430.016
localization of cellGO:00516742440.016
response to hexoseGO:000974630.016
regulation of synaptic growth at neuromuscular junctionGO:000858210.016
gtp metabolic processGO:004603940.016
regulation of sequestering of calcium ionGO:005128240.016
negative regulation of sequestering of calcium ionGO:005128340.016
ribonucleoside monophosphate catabolic processGO:000915840.016
type b pancreatic cell developmentGO:000332340.016
cellular response to lipopolysaccharideGO:007122230.016
response to topologically incorrect proteinGO:003596620.016
nuclear exportGO:005116810.016
regulation of cell killingGO:003134120.016
spindle assemblyGO:005122520.016
positive regulation of nucleic acid templated transcriptionGO:1903508570.016
cell morphogenesis involved in differentiationGO:00009041950.016
regulation of intracellular protein transportGO:003315730.016
erk1 and erk2 cascadeGO:007037140.016
sensory perception of smellGO:000760820.016
eye morphogenesisGO:00485921440.016
epidermis developmentGO:0008544480.016
locomotor rhythmGO:004547530.016
regulation of cell deathGO:00109411030.015
negative regulation of metabolic processGO:0009892860.015
cellular response to external stimulusGO:007149620.015
response to antibioticGO:004667710.015
regulation of mrna processingGO:005068430.015
cytosolic calcium ion transportGO:006040130.015
regulation of dna replicationGO:000627530.015
cellular monovalent inorganic cation homeostasisGO:003000420.015
guanosine containing compound metabolic processGO:190106840.015
stem cell divisionGO:001714510.015
lateral line developmentGO:0048882660.015
cytokinesisGO:000091030.015
photoreceptor cell differentiationGO:0046530550.015
regulation of nucleocytoplasmic transportGO:004682220.015
odontogenesis of dentin containing toothGO:004247510.015
peptidyl serine phosphorylationGO:001810510.015
development of primary female sexual characteristicsGO:004654540.015
negative regulation of response to stimulusGO:00485851040.015
sleepGO:003043110.015
chemosensory behaviorGO:000763510.015
somatic muscle developmentGO:000752540.015
epibolyGO:0090504410.015
blood circulationGO:0008015870.015
toll like receptor signaling pathwayGO:000222440.015
cell cycle g1 s phase transitionGO:004484310.015
cell projection organizationGO:00300302840.015
camera type eye morphogenesisGO:00485931080.015
regulation of reproductive processGO:200024140.015
purine ribonucleoside monophosphate catabolic processGO:000916940.014
cellular response to biotic stimulusGO:007121630.014
mitochondrion organizationGO:000700540.014
response to glucocorticoidGO:005138410.014
polarized epithelial cell differentiationGO:003085940.014
circulatory system processGO:0003013870.014
nitric oxide metabolic processGO:004620920.014
positive regulation of leukocyte mediated immunityGO:000270510.014
liver developmentGO:0001889960.014
establishment of localization in cellGO:0051649770.014
stem cell differentiationGO:00488631170.014
negative regulation of gene expressionGO:0010629650.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
carbohydrate homeostasisGO:003350010.014
interaction with hostGO:005170140.014
regulation of synapse organizationGO:005080730.014
muscle organ developmentGO:00075171010.014
hatchingGO:003518840.014
nucleoside monophosphate catabolic processGO:000912540.014
regulation of programmed cell deathGO:00430671010.014
glucose homeostasisGO:004259310.014
regulation of cellular ketone metabolic processGO:001056570.014
circadian sleep wake cycle processGO:002241020.014
cartilage developmentGO:0051216960.014
regulation of myotube differentiationGO:001083020.014
regulation of cell projection assemblyGO:006049140.014
regulation of circadian sleep wake cycle sleepGO:004518710.014
camera type eye developmentGO:00430102220.014
apoptotic processGO:00069151160.014
negative regulation of secretion by cellGO:190353120.014
complement activationGO:000695630.014
negative regulation of transcription dna templatedGO:0045892450.014
regulation of jun kinase activityGO:004350630.014
positive regulation of notch signaling pathwayGO:004574730.014
regulation of autophagyGO:001050630.014
positive regulation of cellular amine metabolic processGO:003324000.013
negative regulation of protein complex assemblyGO:003133310.013
regulation of blood coagulationGO:003019310.013
negative regulation of defense responseGO:003134820.013
nuclear importGO:005117030.013
axon developmentGO:00615641660.013
cognitionGO:005089010.013
positive regulation of lymphocyte mediated immunityGO:000270810.013
g1 s transition of mitotic cell cycleGO:000008210.013
cell matrix adhesionGO:000716040.013
epithelial cell developmentGO:0002064420.013
positive regulation of canonical wnt signaling pathwayGO:009026340.013
meiosis iGO:000712710.013
axon guidanceGO:0007411860.013
regulation of mrna splicing via spliceosomeGO:004802430.013
skeletal muscle tissue developmentGO:0007519670.013
neurological system processGO:0050877620.013
single organism metabolic processGO:00447102170.013
protein polymerizationGO:005125840.013
regulation of blood pressureGO:000821710.013
regulation of production of molecular mediator of immune responseGO:000270010.013
embryonic heart tube developmentGO:00350501330.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
response to glucoseGO:000974930.013
lens fiber cell morphogenesisGO:007030930.013
regulation of protein import into nucleusGO:004230620.013
spermatid developmentGO:000728620.013
eye photoreceptor cell differentiationGO:0001754450.013
negative regulation of immune responseGO:005077720.013
fin developmentGO:0033333770.013
regulation of protein targetingGO:190353320.013
cell deathGO:00082191210.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
heart morphogenesisGO:00030071560.013
regulation of erk1 and erk2 cascadeGO:007037240.013
centrosome organizationGO:005129710.012
positive regulation of cytoskeleton organizationGO:005149530.012
calcium mediated signalingGO:001972220.012
antimicrobial humoral responseGO:001973020.012
regulation of circadian sleep wake cycleGO:004274910.012
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.012
positive regulation of macromolecule metabolic processGO:0010604930.012
negative regulation of secretionGO:005104820.012
positive regulation of cell communicationGO:0010647560.012
protein stabilizationGO:005082120.012
dna templated transcription initiationGO:000635210.012
forebrain developmentGO:0030900960.012
somatic cell dna recombinationGO:001644410.012
negative regulation of protein localization to nucleusGO:190018120.012
embryonic skeletal system developmentGO:0048706970.012
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.012
negative regulation of dna metabolic processGO:005105340.012
alpha amino acid metabolic processGO:190160530.012
circadian sleep wake cycle sleepGO:005080210.012
regulation of leukocyte mediated immunityGO:000270310.012
regulation of syncytium formation by plasma membrane fusionGO:006014220.012
response to external biotic stimulusGO:0043207970.012
regulation of bindingGO:005109830.012
retina morphogenesis in camera type eyeGO:0060042790.012
peptidyl serine modificationGO:001820920.012
regulation of transportGO:0051049450.012
programmed cell deathGO:00125011190.012
b cell mediated immunityGO:001972430.012
adult behaviorGO:003053420.012
regulation of angiogenesisGO:0045765260.012
regulation of epithelial cell proliferationGO:005067830.012
regulation of nucleoside metabolic processGO:000911820.012
monovalent inorganic cation transportGO:0015672420.012
organelle organizationGO:00069962270.012
regulation of calcium ion transportGO:005192420.012
regulation of neural precursor cell proliferationGO:200017730.012
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.012
i kappab kinase nf kappab signalingGO:000724940.012
heart processGO:0003015710.012
positive regulation of cell cycleGO:004578730.012
neurotransmitter transportGO:000683620.012
determination of heart left right asymmetryGO:00613711170.012
cell substrate adhesionGO:003158940.012
olfactory lobe developmentGO:002198840.012
negative regulation of cell communicationGO:0010648960.012
reactive oxygen species biosynthetic processGO:190340910.012
calcium ion importGO:007050940.011
developmental growth involved in morphogenesisGO:0060560860.011
central nervous system neuron differentiationGO:0021953740.011
cation transmembrane transportGO:0098655650.011
embryonic cranial skeleton morphogenesisGO:0048701900.011
regulation of protein catabolic processGO:004217610.011
spinal cord developmentGO:0021510460.011
negative regulation of multi organism processGO:004390130.011
determination of left right symmetryGO:00073681790.011
gtp catabolic processGO:000618420.011
negative regulation of chromosome organizationGO:200125110.011
tissue migrationGO:0090130370.011
astrocyte differentiationGO:004870810.011
regulation of phospholipase activityGO:001051720.011
positive regulation of cellular catabolic processGO:003133130.011
atp catabolic processGO:000620040.011
sprouting angiogenesisGO:0002040530.011
chemotaxisGO:00069351040.011
xenobiotic metabolic processGO:000680540.011
endoderm developmentGO:0007492490.011
transmission of nerve impulseGO:0019226190.011
actomyosin structure organizationGO:0031032530.011
mesenchyme developmentGO:00604851270.011
regulation of transporter activityGO:003240920.011
carbohydrate biosynthetic processGO:001605110.011
regulation of peptidyl tyrosine phosphorylationGO:005073010.011
positive regulation of dna metabolic processGO:005105410.011
cell agingGO:000756920.011
regulation of vasculature developmentGO:1901342330.011

itk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.024
musculoskeletal system diseaseDOID:1700.016
nervous system diseaseDOID:86300.015
muscular diseaseDOID:008000000.014
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012
immune system diseaseDOID:291400.011