Danio rerio

0 known processes

tln1

talin 1

(Aliases: wu:fb05c02,sb:cb854)

tln1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
single organism localizationGO:19025782250.280
larval developmentGO:000216420.260
Worm
positive regulation of biological processGO:00485182530.234
multicellular organism growthGO:003526440.216
agingGO:000756820.197
single organism metabolic processGO:00447102170.181
protein metabolic processGO:00195381830.180
Worm
stem cell maintenanceGO:001982740.167
digestive tract developmentGO:00485652650.161
regulation of multicellular organism growthGO:004001440.158
transportGO:00068102200.137
Worm
single organism organelle organizationGO:19025891990.125
Mouse
nucleoside monophosphate catabolic processGO:000912540.115
tube morphogenesisGO:00352393490.111
defense responseGO:0006952470.106
cognitionGO:005089010.104
vasculature developmentGO:00019442780.097
Zebrafish
neuron projection developmentGO:00311751800.096
generation of neuronsGO:00486993850.093
anion transportGO:0006820380.092
regulation of cell communicationGO:00106462320.091
regulation of signal transductionGO:00099662250.089
negative regulation of multicellular organismal processGO:0051241690.087
small molecule metabolic processGO:0044281770.086
regulation of erk1 and erk2 cascadeGO:007037240.085
heart developmentGO:00075073130.084
Zebrafish
regulation of synapse assemblyGO:005196330.083
ribonucleoside monophosphate catabolic processGO:000915840.082
cellular biosynthetic processGO:00442492860.081
digestive tract morphogenesisGO:00485462310.079
regulation of exocytosisGO:001715710.074
transmembrane transportGO:00550851200.070
blood vessel morphogenesisGO:00485142160.069
Zebrafish
heterocycle metabolic processGO:00464832900.068
regulation of cytokine productionGO:000181730.067
sensory perception of chemical stimulusGO:000760630.067
muscle tissue developmentGO:00605371100.066
Zebrafish
neuron projection regenerationGO:0031102160.066
purine nucleoside monophosphate catabolic processGO:000912840.064
signal transductionGO:00071654550.064
pole plasm assemblyGO:000731540.062
epithelial cell differentiationGO:00308551160.061
organonitrogen compound metabolic processGO:1901564740.061
neurotransmitter secretionGO:000726920.061
developmental growthGO:00485891660.059
digestive system developmentGO:00551232890.059
phagocytosisGO:000690930.059
establishment of localizationGO:00512342440.057
Worm
regulation of protein ubiquitinationGO:003139630.057
ion transmembrane transportGO:0034220910.057
synaptic growth at neuromuscular junctionGO:005112420.057
atp catabolic processGO:000620040.056
ion transportGO:00068111140.056
regulation of synapse organizationGO:005080730.055
positive regulation of cellular component biogenesisGO:004408930.055
sensory organ developmentGO:00074233930.054
axon developmentGO:00615641660.054
cell morphogenesis involved in differentiationGO:00009041950.053
meiotic nuclear divisionGO:000712640.053
angiogenesisGO:00015251580.052
Zebrafish
exocytosisGO:000688710.051
cell substrate adhesionGO:003158940.051
gastrulationGO:00073692080.050
neurological system processGO:0050877620.050
cell migrationGO:00164772370.050
Worm
regulation of signalingGO:00230512350.048
chemotaxisGO:00069351040.048
actin polymerization or depolymerizationGO:000815420.047
adult behaviorGO:003053420.045
single organism transportGO:00447652060.045
positive regulation of transportGO:005105020.044
cellular amino acid metabolic processGO:000652070.044
negative regulation of cellular processGO:00485232830.043
response to external stimulusGO:00096052640.043
immune system processGO:00023762410.043
cell part morphogenesisGO:00329902460.042
regulation of establishment of protein localizationGO:007020140.042
guanosine containing compound metabolic processGO:190106840.042
regulation of protein modification by small protein conjugation or removalGO:190332030.042
positive regulation of synapse assemblyGO:005196510.042
response to stressGO:00069502630.041
Human
response to external biotic stimulusGO:0043207970.041
negative regulation of biological processGO:00485193040.041
regulation of lipase activityGO:006019120.041
cytokinesisGO:000091030.040
taxisGO:00423301090.040
negative regulation of small gtpase mediated signal transductionGO:005105810.040
regulation of metabolic processGO:00192223590.040
cytoskeleton dependent cytokinesisGO:006164030.039
cellular component morphogenesisGO:00329893360.039
cell morphogenesis involved in neuron differentiationGO:00486671630.039
regulation of synaptic growth at neuromuscular junctionGO:000858210.039
positive regulation of cytokine productionGO:000181920.038
regulation of multicellular organismal developmentGO:20000262230.038
cell projection organizationGO:00300302840.038
regulation of neurotransmitter transportGO:005158810.037
regulation of biological qualityGO:00650082630.037
Human
organophosphate metabolic processGO:0019637370.037
multi organism processGO:00517041340.037
Worm
endothelial cell differentiationGO:0045446200.036
neurotransmitter transportGO:000683620.036
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.036
growthGO:00400071740.036
peptidyl serine modificationGO:001820920.036
gtp catabolic processGO:000618420.035
cellular amine metabolic processGO:004410620.034
cell projection morphogenesisGO:00488582440.034
response to other organismGO:0051707970.034
organic substance biosynthetic processGO:19015762890.034
response to nicotineGO:003509420.033
nitrogen compound metabolic processGO:00068073190.033
establishment of protein localization to organelleGO:007259440.033
cellular protein catabolic processGO:004425740.033
maternal determination of anterior posterior axis embryoGO:000835840.033
cortical cytoskeleton organizationGO:003086510.033
Mouse
embryonic organ developmentGO:00485683810.033
localization of cellGO:00516742440.033
Worm
cytokinetic processGO:003250620.033
response to woundingGO:00096111160.033
Human
oxidation reduction processGO:0055114410.032
oocyte anterior posterior axis specificationGO:000731440.032
peptidyl serine phosphorylationGO:001810510.032
organelle organizationGO:00069962270.032
Zebrafish Mouse
pathway restricted smad protein phosphorylationGO:006038910.032
protein import into nucleusGO:000660630.031
regulation of multicellular organismal processGO:00512392770.031
actin cytoskeleton organizationGO:0030036630.031
Mouse
proteolysis involved in cellular protein catabolic processGO:005160330.031
wound healingGO:0042060900.031
Human
positive regulation of cell cycleGO:004578730.031
neuron developmentGO:00486662620.030
regulation of cell activationGO:005086510.030
amine metabolic processGO:000930820.030
endosomal transportGO:001619720.030
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.030
macromolecular complex subunit organizationGO:0043933740.030
positive regulation of cellular catabolic processGO:003133130.030
regulation of nucleoside metabolic processGO:000911820.030
regulation of response to stimulusGO:00485832690.029
extrinsic apoptotic signaling pathwayGO:009719130.029
developmental maturationGO:0021700340.029
regulation of inflammatory responseGO:005072720.029
axonogenesisGO:00074091520.029
germ line stem cell maintenanceGO:003071820.029
regulation of bindingGO:005109830.029
adherens junction organizationGO:003433240.029
regulation of cellular amine metabolic processGO:003323800.029
purine nucleotide metabolic processGO:0006163270.028
lymphocyte proliferationGO:004665110.028
response to biotic stimulusGO:0009607970.028
neuron projection morphogenesisGO:00488121610.028
regulation of oocyte developmentGO:006028130.027
regulation of cell shapeGO:000836010.027
guanosine containing compound catabolic processGO:190106920.027
compound eye developmentGO:004874920.027
regulation of purine nucleotide catabolic processGO:003312120.027
cellular localizationGO:0051641970.027
cellular component biogenesisGO:00440851780.026
Mouse
positive regulation of erk1 and erk2 cascadeGO:007037420.026
cellular macromolecule metabolic processGO:00442603910.026
regulation of developmental processGO:00507932470.026
eye developmentGO:00016542770.026
morphogenesis of an epitheliumGO:00020093330.026
regulation of biomineral tissue developmentGO:007016720.026
regulation of cellular amino acid metabolic processGO:000652100.026
phosphate containing compound metabolic processGO:00067961080.026
negative regulation of cytokine productionGO:000181810.026
cellular ketone metabolic processGO:0042180110.025
negative regulation of signalingGO:0023057960.025
ras protein signal transductionGO:000726570.025
system processGO:00030081850.025
small gtpase mediated signal transductionGO:000726480.025
cell morphogenesisGO:00009022890.025
cellular component movementGO:00069283350.025
Worm
positive regulation of cell activationGO:005086710.025
g1 s transition of mitotic cell cycleGO:000008210.025
gtp metabolic processGO:004603940.025
negative regulation of reproductive processGO:200024230.025
cellular component assemblyGO:00226071700.025
Mouse
cell surface receptor signaling pathwayGO:00071663250.025
negative regulation of response to stimulusGO:00485851040.024
single organism biosynthetic processGO:0044711710.024
organelle fusionGO:004828430.024
regulation of hormone secretionGO:004688320.024
response to axon injuryGO:0048678140.024
macromolecule modificationGO:00434121110.024
regulation of cell projection assemblyGO:006049140.024
organic cyclic compound metabolic processGO:19013603010.024
immune responseGO:0006955280.024
axon regenerationGO:0031103140.024
regulation of peptidyl tyrosine phosphorylationGO:005073010.023
negative regulation of ras protein signal transductionGO:004658010.023
organonitrogen compound biosynthetic processGO:1901566470.023
neuron differentiationGO:00301823530.023
positive regulation of protein complex assemblyGO:003133420.023
organelle localizationGO:0051640490.023
epibolyGO:0090504410.023
positive regulation of protein kinase b signalingGO:005189710.023
regulation of dendrite developmentGO:005077330.023
oxoacid metabolic processGO:0043436310.023
positive regulation of lipase activityGO:006019310.023
positive regulation of cellular amino acid metabolic processGO:004576400.023
muscle structure developmentGO:00610611960.023
Zebrafish
epithelial cell morphogenesisGO:000338220.023
regulation of cellular ketone metabolic processGO:001056570.023
behaviorGO:0007610740.022
positive regulation of gtp catabolic processGO:003312610.022
cellular nitrogen compound metabolic processGO:00346412900.022
epithelial cell developmentGO:0002064420.022
morphogenesis of an epithelial sheetGO:0002011490.022
sensory perceptionGO:0007600390.022
regionalizationGO:00030022740.022
biosynthetic processGO:00090582940.022
post golgi vesicle mediated transportGO:000689210.022
regulation of extrinsic apoptotic signaling pathwayGO:200123630.022
cellular protein metabolic processGO:00442671290.022
response to glucoseGO:000974930.022
meiotic cell cycle processGO:190304630.022
peptide transportGO:001583310.022
erk1 and erk2 cascadeGO:007037140.022
regulation of stem cell proliferationGO:007209120.022
cell maturationGO:0048469230.021
regulation of protein transportGO:005122330.021
inner ear developmentGO:00488391260.021
regulation of protein targetingGO:190353320.021
homeostatic processGO:00425921420.021
establishment of localization in cellGO:0051649770.021
negative regulation of defense responseGO:003134820.021
nucleotide metabolic processGO:0009117280.021
cellular response to molecule of bacterial originGO:007121930.021
regulation of macromolecule metabolic processGO:00602553170.021
intracellular mrna localizationGO:000829810.021
blood vessel developmentGO:00015682460.021
Zebrafish
carboxylic acid metabolic processGO:0019752220.021
golgi vesicle transportGO:004819330.021
cell deathGO:00082191210.021
phosphorus metabolic processGO:00067931090.020
cellular response to lipopolysaccharideGO:007122230.020
cell cycleGO:0007049930.020
cell substrate junction assemblyGO:000704420.020
Mouse
positive regulation of small gtpase mediated signal transductionGO:005105710.020
lipid storageGO:001991510.020
internal peptidyl lysine acetylationGO:001839320.020
rna localizationGO:000640340.020
sensory perception of smellGO:000760820.020
regulation of rac protein signal transductionGO:003502010.020
neuroblast proliferationGO:000740520.020
negative regulation of developmental processGO:0051093650.019
phagocytosis engulfmentGO:000691110.019
anterior posterior pattern specificationGO:00099521520.019
macromolecule biosynthetic processGO:00090592270.019
cell matrix adhesionGO:000716040.019
positive regulation of secretion by cellGO:190353210.019
negative regulation of signal transductionGO:0009968940.019
cytoskeleton organizationGO:0007010960.019
Zebrafish Mouse
cell adhesion mediated by integrinGO:003362710.019
regulation of leukocyte mediated immunityGO:000270310.019
purine ribonucleoside monophosphate catabolic processGO:000916940.019
positive regulation of nucleoside metabolic processGO:004597910.019
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.019
positive regulation of endothelial cell proliferationGO:000193810.019
cell projection assemblyGO:0030031640.018
membrane invaginationGO:001032410.018
stem cell proliferationGO:007208940.018
energy reserve metabolic processGO:000611220.018
positive regulation of cellular processGO:00485222010.018
regulation of neurotransmitter secretionGO:004692810.018
maintenance of locationGO:005123540.018
regulation of meiotic cell cycleGO:005144510.018
regulation of epithelial cell proliferationGO:005067830.018
regulation of sodium ion transportGO:000202820.018
response to chemicalGO:00422213200.018
establishment of organelle localizationGO:0051656450.018
cellular extravasationGO:004512310.018
cellular aromatic compound metabolic processGO:00067252950.017
convergent extensionGO:00600261180.017
carboxylic acid catabolic processGO:004639530.017
embryonic hemopoiesisGO:0035162530.017
modification dependent macromolecule catabolic processGO:004363230.017
negative regulation of cell communicationGO:0010648960.017
cell chemotaxisGO:0060326170.017
glucose importGO:004632320.017
regulation of rho protein signal transductionGO:003502320.017
oocyte maturationGO:000155640.017
response to carbohydrateGO:000974330.017
glial cell migrationGO:000834730.017
sexual reproductionGO:0019953360.017
Worm
cellular component disassemblyGO:002241110.016
regulation of nucleotide catabolic processGO:003081120.016
rho protein signal transductionGO:000726650.016
mononuclear cell proliferationGO:003294310.016
regulation of cytoplasmic transportGO:190364940.016
carbohydrate homeostasisGO:003350010.016
cardiac ventricle morphogenesisGO:000320870.016
ventricular cardiac muscle tissue morphogenesisGO:005501020.016
establishment of synaptic vesicle localizationGO:009748010.016
peptidyl threonine phosphorylationGO:001810710.016
regenerationGO:0031099910.016
membrane lipid biosynthetic processGO:004646720.016
regulation of gtpase activityGO:004308720.016
endothelium developmentGO:0003158250.016
activation of mapk activityGO:000018730.016
single organism membrane fusionGO:004480120.016
positive regulation of metabolic processGO:00098931080.016
negative regulation of chemotaxisGO:005092240.015
ameboidal type cell migrationGO:00016671430.015
cardiac muscle tissue developmentGO:0048738480.015
Zebrafish
positive regulation of lipid metabolic processGO:004583410.015
organelle assemblyGO:00709251100.015
deathGO:00162651210.015
regulation of protein import into nucleusGO:004230620.015
regulation of developmental growthGO:0048638380.015
biological adhesionGO:0022610400.015
Human
trabecula morphogenesisGO:006138320.015
cardiac chamber developmentGO:0003205190.015
positive regulation of catabolic processGO:000989640.015
positive regulation of immune effector processGO:000269930.015
estrogen metabolic processGO:000821020.015
actin filament based movementGO:003004810.015
synaptic vesicle transportGO:004848910.015
regulation of protein complex assemblyGO:004325430.015
neuron projection guidanceGO:0097485860.015
regulation of protein kinase b signalingGO:005189680.015
protein modification processGO:00362111000.015
actin filament polymerizationGO:003004120.015
protein polymerizationGO:005125840.015
response to organic substanceGO:00100331530.015
immunoglobulin productionGO:000237710.014
regulation of cell substrate adhesionGO:001081010.014
nucleobase containing small molecule metabolic processGO:0055086320.014
protein secretionGO:000930610.014
cell migration involved in gastrulationGO:0042074790.014
macromolecule catabolic processGO:0009057150.014
Worm
proteasomal protein catabolic processGO:001049820.014
glucose homeostasisGO:004259310.014
regulation of blood vessel sizeGO:005088020.014
negative regulation of immune responseGO:005077720.014
sphingolipid biosynthetic processGO:003014820.014
carbohydrate derivative metabolic processGO:1901135610.014
amino acid transportGO:000686520.014
cellular protein modification processGO:00064641000.014
internal protein amino acid acetylationGO:000647520.014
protein targeting to nucleusGO:004474430.014
striated muscle cell developmentGO:00550021080.014
visual behaviorGO:0007632100.014
single organism nuclear importGO:190259330.014
nucleobase containing compound metabolic processGO:00061392740.014
negative regulation of synapse assemblyGO:005196420.014
urogenital system developmentGO:0001655970.014
actomyosin structure organizationGO:0031032530.014
cellular component assembly involved in morphogenesisGO:00109271070.014
regulation of wnt signaling pathwayGO:0030111530.014
wnt signaling pathwayGO:0016055800.014
regulation of hydrolase activityGO:0051336280.014
regulation of intracellular protein transportGO:003315730.014
heterocycle biosynthetic processGO:00181302150.014
collagen fibril organizationGO:003019910.014
axon guidanceGO:0007411860.013
embryo development ending in birth or egg hatchingGO:00097922710.013
Worm
ventricular cardiac muscle tissue developmentGO:000322930.013
protein complex disassemblyGO:004324110.013
proteolysisGO:0006508380.013
cell activationGO:0001775160.013
Human
organic acid metabolic processGO:0006082310.013
positive regulation of cell adhesionGO:004578510.013
cell cycle g1 s phase transitionGO:004484310.013
regulation of ras gtpase activityGO:003231820.013
response to abiotic stimulusGO:00096281220.013
establishment of endothelial barrierGO:006102830.013
defense response to other organismGO:0098542330.013
regulation of receptor recyclingGO:000191930.013
single organism cellular localizationGO:1902580460.013
peptidyl tyrosine phosphorylationGO:001810850.013
detection of stimulusGO:0051606290.013
response to drugGO:004249330.013
tissue migrationGO:0090130370.013
cardiac atrium morphogenesisGO:000320920.013
nucleocytoplasmic transportGO:000691340.013
organic anion transportGO:0015711150.013
regulation of natural killer cell mediated immunityGO:000271510.013
stem cell divisionGO:001714510.013
pyrimidine containing compound metabolic processGO:007252730.013
cation transmembrane transportGO:0098655650.013
regulation of gtp catabolic processGO:003312420.012
regulation of transportGO:0051049450.012
immune system developmentGO:00025201910.012
specification of symmetryGO:00097992040.012
regulation of gene expressionGO:00104682650.012
reactive oxygen species metabolic processGO:007259360.012
ear developmentGO:00435831270.012
positive regulation of epithelial cell differentiationGO:003085820.012
circulatory system processGO:0003013870.012
ubiquitin dependent protein catabolic processGO:000651130.012
regulation of multicellular organismal metabolic processGO:004424620.012
segmentationGO:0035282970.012
synaptic vesicle localizationGO:009747910.012
mitochondrial transportGO:000683920.012
positive regulation of gtpase activityGO:004354710.012
regulation of cell projection organizationGO:0031344440.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
cardiac cell fate commitmentGO:006091110.012
locomotionGO:00400113130.012
Worm
cellular response to biotic stimulusGO:007121630.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
regulation of receptor mediated endocytosisGO:004825940.012
positive regulation of cytoskeleton organizationGO:005149530.012
mrna 3 end processingGO:003112420.012
membrane fusionGO:006102520.012
regulation of neural precursor cell proliferationGO:200017730.012
ribonucleotide metabolic processGO:0009259270.012
cellular carbohydrate metabolic processGO:004426240.012
axon extensionGO:0048675450.012
defense response to fungusGO:005083220.012
cellular response to external stimulusGO:007149620.012
modification dependent protein catabolic processGO:001994130.012
organic substance transportGO:0071702580.012
regulation of reactive oxygen species metabolic processGO:200037720.012
carbohydrate biosynthetic processGO:001605110.012
lamellipodium organizationGO:009758110.012
embryonic pattern specificationGO:0009880440.012
response to alkaloidGO:004327920.012
neuromuscular process controlling balanceGO:005088530.012
hormone secretionGO:004687920.012
muscle cell differentiationGO:00426921390.012
protein localization to nucleusGO:003450430.012
heart joggingGO:0003146400.012
inflammatory responseGO:000695480.012
regulation of cell differentiationGO:00455951420.011
cell cycle processGO:0022402530.011
reflexGO:006000420.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
hormone transportGO:000991420.011
central nervous system developmentGO:00074173870.011
single organism behaviorGO:0044708240.011
sex determinationGO:000753010.011
regulation of reproductive processGO:200024140.011
gland developmentGO:00487321430.011
positive regulation of notch signaling pathwayGO:004574730.011
negative regulation of multi organism processGO:004390130.011
regulation of circadian rhythmGO:004275240.011
nucleoside phosphate metabolic processGO:0006753280.011
regulation of cellular protein metabolic processGO:0032268520.011
cellular component maintenanceGO:004395430.011
receptor recyclingGO:000188140.011
actin mediated cell contractionGO:007025210.011
regulation of phospholipase activityGO:001051720.011
muscle organ developmentGO:00075171010.011
Zebrafish
regulation of protein bindingGO:004339330.011
multicellular organism reproductionGO:0032504350.011
Worm
protein acylationGO:004354330.011
hormone metabolic processGO:0042445190.011
multicellular organismal macromolecule metabolic processGO:004425920.011
regulation of growth rateGO:004000910.011
positive regulation of nucleotide catabolic processGO:003081310.011
positive regulation of map kinase activityGO:004340630.011
catabolic processGO:0009056320.011
Worm
camera type eye morphogenesisGO:00485931080.011
regulation of bone mineralizationGO:003050020.011
cellular response to oxygen containing compoundGO:1901701200.011
negative regulation of cell differentiationGO:0045596460.011
receptor internalizationGO:003162320.011
positive regulation of multicellular organismal processGO:0051240520.011
secondary metabolic processGO:001974830.011
regulation of molecular functionGO:0065009700.011
organic cyclic compound biosynthetic processGO:19013622230.011
regulation of dna templated transcription in response to stressGO:004362000.011
embryonic camera type eye morphogenesisGO:0048596190.011
positive regulation of secretionGO:005104710.011
detection of abiotic stimulusGO:0009582240.010
protein localization to plasma membraneGO:007265910.010
positive regulation of neuron differentiationGO:0045666120.010
response to monosaccharideGO:003428430.010
production of molecular mediator of immune responseGO:000244020.010
response to corticosteroidGO:003196010.010
regulation of production of molecular mediator of immune responseGO:000270010.010
inorganic ion transmembrane transportGO:0098660570.010
steroid metabolic processGO:000820270.010
regulation of localizationGO:00328791040.010
cytoplasm organizationGO:000702840.010
protein dephosphorylationGO:000647030.010
regulation of vesicle mediated transportGO:006062790.010
somite developmentGO:0061053960.010
regulation of myotube differentiationGO:001083020.010
positive regulation of cell substrate adhesionGO:001081110.010
positive regulation of cellular amine metabolic processGO:003324000.010

tln1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.039
disease of metabolismDOID:001466700.028
muscular diseaseDOID:008000000.018
musculoskeletal system diseaseDOID:1700.018
connective tissue diseaseDOID:6500.014
bone diseaseDOID:008000100.014
inherited metabolic disorderDOID:65500.011