Danio rerio

60 known processes

fto

fat mass and obesity associated

fto biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.059
agingGO:000756820.054
maintenance of locationGO:005123540.042
cellular protein catabolic processGO:004425740.039
signal transductionGO:00071654550.037
positive regulation of transportGO:005105020.034
phagocytosisGO:000690930.033
autophagyGO:000691440.032
proteolysis involved in cellular protein catabolic processGO:005160330.032
regulation of multicellular organism growthGO:004001440.031
regulation of neural precursor cell proliferationGO:200017730.031
positive regulation of cellular component biogenesisGO:004408930.030
protein localization to nucleusGO:003450430.030
stem cell maintenanceGO:001982740.030
positive regulation of cell cycleGO:004578730.030
lipid storageGO:001991510.029
nucleocytoplasmic transportGO:000691340.029
i kappab kinase nf kappab signalingGO:000724940.029
response to drugGO:004249330.029
gtp metabolic processGO:004603940.029
regulation of autophagyGO:001050630.029
multicellular organism growthGO:003526440.029
negative regulation of protein phosphorylationGO:000193340.028
cellular response to external stimulusGO:007149620.028
response to chemicalGO:00422213200.028
nuclear transportGO:005116940.028
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.028
modification dependent protein catabolic processGO:001994130.028
negative regulation of biological processGO:00485193040.027
ubiquitin dependent protein catabolic processGO:000651130.027
sensory organ developmentGO:00074233930.027
modification dependent macromolecule catabolic processGO:004363230.027
proteasomal protein catabolic processGO:001049820.027
nitrogen compound metabolic processGO:00068073190.027
protein targeting to nucleusGO:004474430.027
cell surface receptor signaling pathwayGO:00071663250.026
tube morphogenesisGO:00352393490.026
stem cell proliferationGO:007208940.026
establishment of protein localization to organelleGO:007259440.026
cellular nitrogen compound metabolic processGO:00346412900.026
embryonic organ developmentGO:00485683810.026
regulation of protein transportGO:005122330.025
positive regulation of catabolic processGO:000989640.025
embryonic organ morphogenesisGO:00485622740.025
regulation of establishment of protein localizationGO:007020140.025
regulation of cytoplasmic transportGO:190364940.025
regulation of protein catabolic processGO:004217610.025
amine metabolic processGO:000930820.025
digestive system developmentGO:00551232890.024
cell substrate adhesionGO:003158940.024
single organism nuclear importGO:190259330.024
vasculature developmentGO:00019442780.024
regulation of metal ion transportGO:001095940.024
regulation of synaptic plasticityGO:004816710.024
regulation of protein complex assemblyGO:004325430.024
regulation of cytokine productionGO:000181730.023
positive regulation of cellular catabolic processGO:003133130.023
digestive tract developmentGO:00485652650.023
negative regulation of protein kinase activityGO:000646940.023
regulation of cell activationGO:005086510.023
single organism metabolic processGO:00447102170.023
central nervous system developmentGO:00074173870.023
positive regulation of cytoskeleton organizationGO:005149530.023
regulation of i kappab kinase nf kappab signalingGO:004312240.023
neuron neuron synaptic transmissionGO:000727010.022
cellular response to nutrient levelsGO:003166920.022
mitochondrion organizationGO:000700540.022
morphogenesis of an epitheliumGO:00020093330.022
cellular amine metabolic processGO:004410620.022
gtp catabolic processGO:000618420.022
cellular component movementGO:00069283350.022
regulation of multicellular organismal processGO:00512392770.022
heart developmentGO:00075073130.022
response to carbohydrateGO:000974330.022
guanosine containing compound metabolic processGO:190106840.022
extrinsic apoptotic signaling pathwayGO:009719130.022
protein import into nucleusGO:000660630.022
nuclear importGO:005117030.022
biosynthetic processGO:00090582940.021
blood vessel morphogenesisGO:00485142160.021
leukocyte proliferationGO:007066110.021
regulation of cellular amine metabolic processGO:003323800.021
head developmentGO:00603223030.021
guanosine containing compound catabolic processGO:190106920.021
oxoacid metabolic processGO:0043436310.021
regulation of nucleocytoplasmic transportGO:004682220.021
regulation of intracellular protein transportGO:003315730.021
organic acid metabolic processGO:0006082310.021
brain developmentGO:00074202930.021
regulation of cellular metabolic processGO:00313233200.021
heterocycle biosynthetic processGO:00181302150.021
cellular macromolecule metabolic processGO:00442603910.020
protein importGO:001703830.020
antimicrobial humoral responseGO:001973020.020
cellular biosynthetic processGO:00442492860.020
response to organic substanceGO:00100331530.020
blood vessel developmentGO:00015682460.020
gastrulationGO:00073692080.020
regulation of cellular amino acid metabolic processGO:000652100.020
regulation of synapse organizationGO:005080730.020
positive regulation of protein complex assemblyGO:003133420.020
heterocycle metabolic processGO:00464832900.020
cellular aromatic compound metabolic processGO:00067252950.020
negative regulation of cellular processGO:00485232830.019
nucleobase containing compound metabolic processGO:00061392740.019
cellular response to extracellular stimulusGO:003166820.019
cellular response to starvationGO:000926710.019
response to uvGO:000941130.019
regulation of protein localization to nucleusGO:190018020.019
response to stressGO:00069502630.019
cognitionGO:005089010.019
response to monosaccharideGO:003428430.019
meiotic cell cycle processGO:190304630.019
neurotransmitter transportGO:000683620.019
regulation of cell shapeGO:000836010.019
negative regulation of kinase activityGO:003367340.019
immune system processGO:00023762410.019
regulation of response to stimulusGO:00485832690.019
peptide transportGO:001583310.019
phagocytosis engulfmentGO:000691110.019
response to external stimulusGO:00096052640.019
carboxylic acid metabolic processGO:0019752220.019
centrosome organizationGO:005129710.019
organonitrogen compound metabolic processGO:1901564740.019
regulation of stem cell proliferationGO:007209120.019
organelle fusionGO:004828430.019
single organism organelle organizationGO:19025891990.019
cellular ketone metabolic processGO:0042180110.019
cytokinesisGO:000091030.019
regulation of metabolic processGO:00192223590.019
meiotic nuclear divisionGO:000712640.019
eye developmentGO:00016542770.019
locomotionGO:00400113130.018
membrane fusionGO:006102520.018
female gonad developmentGO:000858540.018
cell projection morphogenesisGO:00488582440.018
regulation of cellular ketone metabolic processGO:001056570.018
response to hexoseGO:000974630.018
cell matrix adhesionGO:000716040.018
cellular response to chemical stimulusGO:00708871570.018
nucleic acid metabolic processGO:00903042440.018
organic substance biosynthetic processGO:19015762890.018
cellular response to oxygen levelsGO:007145310.018
regulation of synapse assemblyGO:005196330.018
cell part morphogenesisGO:00329902460.018
regulation of protein modification by small protein conjugation or removalGO:190332030.018
compound eye developmentGO:004874920.018
digestive tract morphogenesisGO:00485462310.018
organic cyclic compound metabolic processGO:19013603010.018
regulation of protein import into nucleusGO:004230620.018
protein acetylationGO:000647320.018
actin polymerization or depolymerizationGO:000815420.018
peptidyl lysine acetylationGO:001839420.018
exocytosisGO:000688710.018
gene expressionGO:00104672520.018
macromolecule biosynthetic processGO:00090592270.017
regulation of protein ubiquitinationGO:003139630.017
membrane invaginationGO:001032410.017
positive regulation of i kappab kinase nf kappab signalingGO:004312330.017
chordate embryonic developmentGO:00430092710.017
nucleobase containing compound biosynthetic processGO:00346542050.017
cellular nitrogen compound biosynthetic processGO:00442712180.017
cellular carbohydrate metabolic processGO:004426240.017
tissue remodelingGO:004877140.017
negative regulation of catabolic processGO:000989530.017
regulation of bindingGO:005109830.017
single organism membrane fusionGO:004480120.017
regulation of peptidyl tyrosine phosphorylationGO:005073010.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
cellular amino acid metabolic processGO:000652070.017
regulation of protein targetingGO:190353320.017
cell morphogenesisGO:00009022890.017
generation of neuronsGO:00486993850.017
adult behaviorGO:003053420.017
cellular component morphogenesisGO:00329893360.017
system processGO:00030081850.017
regulation of multicellular organismal developmentGO:20000262230.017
regulation of reproductive processGO:200024140.017
cellular amide metabolic processGO:004360340.017
locomotor rhythmGO:004547530.017
neurotransmitter secretionGO:000726920.017
regulation of circadian rhythmGO:004275240.017
female sex differentiationGO:004666040.017
small molecule metabolic processGO:0044281770.017
positive regulation of secretionGO:005104710.017
cell migrationGO:00164772370.016
microtubule organizing center organizationGO:003102310.016
regulation of primary metabolic processGO:00800903110.016
b cell activationGO:004211320.016
synaptic growth at neuromuscular junctionGO:005112420.016
internal peptidyl lysine acetylationGO:001839320.016
regulation of extrinsic apoptotic signaling pathwayGO:200123630.016
cell projection organizationGO:00300302840.016
cellular component assembly involved in morphogenesisGO:00109271070.016
secondary metabolic processGO:001974830.016
protein dephosphorylationGO:000647030.016
peptidyl serine phosphorylationGO:001810510.016
hormone secretionGO:004687920.016
regulation of meiotic cell cycleGO:005144510.016
neuroblast proliferationGO:000740520.016
negative regulation of cellular catabolic processGO:003133030.016
adherens junction organizationGO:003433240.016
angiogenesisGO:00015251580.016
carbohydrate homeostasisGO:003350010.016
internal protein amino acid acetylationGO:000647520.016
mononuclear cell proliferationGO:003294310.016
response to alkaloidGO:004327920.016
localization of cellGO:00516742440.016
cellular response to biotic stimulusGO:007121630.016
rna localizationGO:000640340.016
cellular response to hypoxiaGO:007145610.016
hormone transportGO:000991420.016
negative regulation of protein transportGO:005122430.016
regulation of wound healingGO:006104120.016
regulation of reactive oxygen species metabolic processGO:200037720.016
cilium assemblyGO:0042384580.016
protein localization to plasma membraneGO:007265910.016
regionalizationGO:00030022740.015
positive regulation of dna metabolic processGO:005105410.015
regulation of biosynthetic processGO:00098892500.015
regulation of signal transductionGO:00099662250.015
single fertilizationGO:000733830.015
protein metabolic processGO:00195381830.015
lipid catabolic processGO:001604240.015
peptidyl serine modificationGO:001820920.015
regulation of macromolecule metabolic processGO:00602553170.015
cellular response to radiationGO:007147840.015
regulation of cell communicationGO:00106462320.015
regulation of neuronal synaptic plasticityGO:004816810.015
positive regulation of cytokine productionGO:000181920.015
regulation of blood pressureGO:000821710.015
production of molecular mediator of immune responseGO:000244020.015
protein acylationGO:004354330.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
positive regulation of secretion by cellGO:190353210.015
neuron differentiationGO:00301823530.015
cellular response to molecule of bacterial originGO:007121930.015
synaptic vesicle localizationGO:009747910.015
regulation of purine nucleotide catabolic processGO:003312120.015
regulation of signalingGO:00230512350.015
organelle organizationGO:00069962270.015
lymphocyte proliferationGO:004665110.015
response to corticosteroidGO:003196010.015
protein polymerizationGO:005125840.015
regulation of mrna processingGO:005068430.015
muscle structure developmentGO:00610611960.015
regulation of stem cell differentiationGO:200073640.015
transportGO:00068102200.015
rna metabolic processGO:00160702190.015
regulation of inflammatory responseGO:005072720.014
regulation of nitrogen compound metabolic processGO:00511712510.014
post embryonic organ developmentGO:004856940.014
single organism localizationGO:19025782250.014
cellular response to light stimulusGO:007148240.014
camera type eye developmentGO:00430102220.014
sleepGO:003043110.014
embryo development ending in birth or egg hatchingGO:00097922710.014
glucose homeostasisGO:004259310.014
peptide metabolic processGO:000651810.014
development of primary female sexual characteristicsGO:004654540.014
regulation of cell substrate adhesionGO:001081010.014
positive regulation of cell activationGO:005086710.014
gland developmentGO:00487321430.014
aromatic compound biosynthetic processGO:00194382170.014
establishment of localizationGO:00512342440.014
synaptic vesicle transportGO:004848910.014
regulation of nucleoside metabolic processGO:000911820.014
regulation of dendrite morphogenesisGO:004881430.014
regulation of gene expressionGO:00104682650.014
stem cell divisionGO:001714510.014
intracellular signal transductionGO:0035556850.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
regulation of dna replicationGO:000627530.014
negative regulation of protein serine threonine kinase activityGO:007190120.014
cellular response to decreased oxygen levelsGO:003629410.014
liver developmentGO:0001889960.014
actin filament polymerizationGO:003004120.014
somatic muscle developmentGO:000752540.014
regulation of protein polymerizationGO:003227120.014
establishment of synaptic vesicle localizationGO:009748010.014
cellular macromolecule biosynthetic processGO:00346452240.014
cell motilityGO:00488702440.014
regulation of cellular biosynthetic processGO:00313262450.014
regulation of cellular protein catabolic processGO:190336210.014
endosomal transportGO:001619720.014
determination of bilateral symmetryGO:00098552040.013
positive regulation of cellular amine metabolic processGO:003324000.013
regulation of muscle contractionGO:000693730.013
sensory organ morphogenesisGO:00905962000.013
nuclear exportGO:005116810.013
hemopoiesisGO:00300971830.013
regulation of ion transmembrane transporter activityGO:003241220.013
regulation of organ growthGO:004662030.013
cellular response to lipopolysaccharideGO:007122230.013
nuclear migrationGO:000709730.013
cellular response to xenobiotic stimulusGO:0071466350.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
regulation of sequestering of calcium ionGO:005128240.013
golgi vesicle transportGO:004819330.013
regulation of tube sizeGO:003515020.013
macroautophagyGO:001623610.013
actin filament based movementGO:003004810.013
purine nucleoside monophosphate catabolic processGO:000912840.013
cellular response to organic substanceGO:00713101050.013
specification of symmetryGO:00097992040.013
regulation of developmental processGO:00507932470.013
homeostatic processGO:00425921420.013
regulation of calcium ion transportGO:005192420.013
cellular component disassemblyGO:002241110.013
regulation of dendrite developmentGO:005077330.013
organic cyclic compound biosynthetic processGO:19013622230.013
regulation of biological qualityGO:00650082630.013
protein secretionGO:000930610.013
regulation of erk1 and erk2 cascadeGO:007037240.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
sequestering of metal ionGO:005123830.013
neuron developmentGO:00486662620.013
regulation of nucleotide catabolic processGO:003081120.013
positive regulation of translationGO:004572710.013
positive regulation of protein polymerizationGO:003227320.013
carbohydrate biosynthetic processGO:001605110.013
cellular protein metabolic processGO:00442671290.013
immune system developmentGO:00025201910.013
symbiosis encompassing mutualism through parasitismGO:004440340.012
nucleoside monophosphate catabolic processGO:000912540.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
sequestering of calcium ionGO:005120830.012
chemosensory behaviorGO:000763510.012
meiotic chromosome segregationGO:004513230.012
regulation of production of molecular mediator of immune responseGO:000270010.012
regulation of cell projection assemblyGO:006049140.012
synaptic transmission cholinergicGO:000727140.012
cellular component assemblyGO:00226071700.012
multi organism processGO:00517041340.012
response to glucoseGO:000974930.012
negative regulation of epithelial cell proliferationGO:005068010.012
fertilizationGO:000956630.012
interspecies interaction between organismsGO:004441940.012
regulation of neurotransmitter transportGO:005158810.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
cilium organizationGO:0044782710.012
response to other organismGO:0051707970.012
pigment granule localizationGO:0051875250.012
negative regulation of defense responseGO:003134820.012
hepaticobiliary system developmentGO:0061008980.012
negative regulation of map kinase activityGO:004340720.012
transcription dna templatedGO:00063511810.012
negative regulation of intracellular transportGO:003238730.012
response to external biotic stimulusGO:0043207970.012
positive regulation of cell adhesionGO:004578510.012
regulation of carbohydrate metabolic processGO:000610940.012
negative regulation of nucleocytoplasmic transportGO:004682320.012
purine ribonucleoside monophosphate catabolic processGO:000916940.012
positive regulation of nucleoside metabolic processGO:004597910.012
skeletal system developmentGO:00015011810.012
cellular pigmentationGO:0033059300.012
negative regulation of mapk cascadeGO:004340940.012
cellular component biogenesisGO:00440851780.012
negative regulation of dna metabolic processGO:005105340.012
regulation of organelle assemblyGO:190211540.012
regulation of dna templated transcription in response to stressGO:004362000.012
positive regulation of nucleotide catabolic processGO:003081310.012
response to nutrientGO:000758430.012
negative regulation of cytoplasmic transportGO:190365020.012
atp catabolic processGO:000620040.011
translational initiationGO:000641330.011
cilium morphogenesisGO:0060271850.011
tube closureGO:006060610.011
somatic stem cell maintenanceGO:003501910.011
regulation of response to biotic stimulusGO:000283120.011
regulation of neurotransmitter secretionGO:004692810.011
regulation of blood vessel sizeGO:005088020.011
nucleic acid templated transcriptionGO:00976591810.011
response to glucocorticoidGO:005138410.011
small molecule catabolic processGO:004428230.011
erk1 and erk2 cascadeGO:007037140.011
rna biosynthetic processGO:00327741810.011
developmental growthGO:00485891660.011
response to abiotic stimulusGO:00096281220.011
negative regulation of protein complex assemblyGO:003133310.011
regulation of cellular carbohydrate metabolic processGO:001067540.011
response to endogenous stimulusGO:0009719830.011
negative regulation of intracellular protein transportGO:009031730.011
cell substrate junction assemblyGO:000704420.011
regulation of gtp catabolic processGO:003312420.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
xenobiotic metabolic processGO:000680540.011
regulation of transmembrane transporter activityGO:002289820.011
b cell differentiationGO:003018310.011
regulation of protein bindingGO:004339330.011
positive regulation of immune effector processGO:000269930.011
negative regulation of synapse assemblyGO:005196420.011
cellular lipid catabolic processGO:004424230.011
signal transduction in absence of ligandGO:003803410.011
inner ear developmentGO:00488391260.011
response to biotic stimulusGO:0009607970.011
cilium movementGO:0003341260.011
negative regulation of cytokine productionGO:000181810.011
regulation of epithelial cell proliferationGO:005067830.011
regulation of gtpase activityGO:004308720.011
melanosome localizationGO:0032400210.011
lateral inhibitionGO:004633110.011
regulation of transporter activityGO:003240920.011
positive regulation of biological processGO:00485182530.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
sensory perception of painGO:001923310.011
protein homooligomerizationGO:005126030.011
cytoskeleton dependent cytokinesisGO:006164030.011
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.011
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.011
establishment of pigment granule localizationGO:0051905220.011
negative regulation of protein import into nucleusGO:004230820.011
inositol lipid mediated signalingGO:004801720.011
ear developmentGO:00435831270.011
spermatid differentiationGO:004851520.011
retina development in camera type eyeGO:00600411460.011
dorsal ventral pattern formationGO:00099531250.010
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.010
protein complex disassemblyGO:004324110.010
convergent extensionGO:00600261180.010
heart morphogenesisGO:00030071560.010
nucleic acid transportGO:005065720.010
positive regulation of myeloid cell differentiationGO:004563920.010
cellular transition metal ion homeostasisGO:004691630.010
spermatid developmentGO:000728620.010
regulation of macromolecule biosynthetic processGO:00105562250.010
negative regulation of macromolecule metabolic processGO:0010605760.010
regulation of localizationGO:00328791040.010
striated muscle cell developmentGO:00550021080.010
mitochondrial transportGO:000683920.010
mitotic dna integrity checkpointGO:004477440.010
startle responseGO:000196440.010
g protein coupled receptor signaling pathwayGO:0007186740.010
superoxide metabolic processGO:000680120.010
ribonucleoside monophosphate catabolic processGO:000915840.010
growthGO:00400071740.010
regulation of hormone secretionGO:004688320.010
developmental programmed cell deathGO:001062340.010
regulation of rna metabolic processGO:00512522240.010
hematopoietic or lymphoid organ developmentGO:00485341910.010
determination of left right symmetryGO:00073681790.010
blood circulationGO:0008015870.010
energy reserve metabolic processGO:000611220.010
macromolecular complex disassemblyGO:003298410.010
cell cycle g1 s phase transitionGO:004484310.010
positive regulation of leukocyte mediated immunityGO:000270510.010
positive regulation of canonical wnt signaling pathwayGO:009026340.010
positive regulation of leukocyte differentiationGO:190210710.010
regulation of mrna splicing via spliceosomeGO:004802430.010
response to woundingGO:00096111160.010

fto disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.038
nervous system diseaseDOID:86300.023
musculoskeletal system diseaseDOID:1700.019
cardiovascular system diseaseDOID:128700.017
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.014
disease of metabolismDOID:001466700.014
organ system cancerDOID:005068600.014
sensory system diseaseDOID:005015500.011
myopathyDOID:42300.011
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011
immune system diseaseDOID:291400.011
eye and adnexa diseaseDOID:149200.011
eye diseaseDOID:561400.011
inherited metabolic disorderDOID:65500.011