Danio rerio

0 known processes

hgd

homogentisate 1,2-dioxygenase

(Aliases: hgo)

hgd biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.485
organic acid catabolic processGO:001605430.445
organic acid metabolic processGO:0006082310.441
Mouse
multicellular organism growthGO:003526440.437
small molecule catabolic processGO:004428230.356
agingGO:000756820.269
growthGO:00400071740.261
sensory organ developmentGO:00074233930.225
cellular response to estrogen stimulusGO:0071391240.204
regulation of multicellular organism growthGO:004001440.202
carboxylic acid catabolic processGO:004639530.179
developmental growthGO:00485891660.172
nitrogen compound metabolic processGO:00068073190.163
Mouse
sensory organ morphogenesisGO:00905962000.162
regulation of nitrogen compound metabolic processGO:00511712510.151
central nervous system developmentGO:00074173870.145
nucleic acid templated transcriptionGO:00976591810.139
cellular nitrogen compound biosynthetic processGO:00442712180.138
regulation of multicellular organismal processGO:00512392770.130
positive regulation of transportGO:005105020.127
embryonic organ developmentGO:00485683810.118
heart developmentGO:00075073130.117
oxidation reduction processGO:0055114410.117
biosynthetic processGO:00090582940.111
cellular amine metabolic processGO:004410620.110
single organism localizationGO:19025782250.110
heterocycle biosynthetic processGO:00181302150.110
maintenance of locationGO:005123540.110
response to ketoneGO:190165410.107
cellular aromatic compound metabolic processGO:00067252950.106
embryonic organ morphogenesisGO:00485622740.105
transcription from rna polymerase ii promoterGO:0006366800.104
cognitionGO:005089010.101
organic cyclic compound metabolic processGO:19013603010.099
neurotransmitter transportGO:000683620.098
skeletal system developmentGO:00015011810.096
establishment of protein localization to organelleGO:007259440.096
amine metabolic processGO:000930820.094
regulation of biosynthetic processGO:00098892500.094
enzyme linked receptor protein signaling pathwayGO:00071671060.094
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.092
cellular ketone metabolic processGO:0042180110.091
cell migrationGO:00164772370.090
aromatic compound biosynthetic processGO:00194382170.090
alpha amino acid metabolic processGO:190160530.089
nucleobase containing compound biosynthetic processGO:00346542050.089
response to woundingGO:00096111160.088
oxoacid metabolic processGO:0043436310.081
Mouse
regulation of establishment of protein localizationGO:007020140.079
alcohol biosynthetic processGO:004616520.075
protein targeting to nucleusGO:004474430.075
single organism transportGO:00447652060.074
cellular nitrogen compound metabolic processGO:00346412900.074
heterocycle metabolic processGO:00464832900.073
wound healingGO:0042060900.073
rna metabolic processGO:00160702190.072
small molecule metabolic processGO:0044281770.072
Mouse
regulation of cell shapeGO:000836010.070
generation of neuronsGO:00486993850.069
organic cyclic compound biosynthetic processGO:19013622230.068
negative regulation of synapse assemblyGO:005196420.067
macromolecule biosynthetic processGO:00090592270.066
response to alkaloidGO:004327920.064
cellular localizationGO:0051641970.064
negative regulation of biological processGO:00485193040.064
single organism organelle organizationGO:19025891990.063
Worm
reproductionGO:0000003400.063
regulation of nucleic acid templated transcriptionGO:19035062130.062
regulation of rna metabolic processGO:00512522240.062
cellular response to chemical stimulusGO:00708871570.060
cellular biosynthetic processGO:00442492860.060
regulation of macromolecule biosynthetic processGO:00105562250.059
cellular response to organic cyclic compoundGO:0071407380.058
carboxylic acid metabolic processGO:0019752220.057
Mouse
regulation of biological qualityGO:00650082630.057
regulation of response to stimulusGO:00485832690.057
nucleic acid metabolic processGO:00903042440.057
regulation of rna biosynthetic processGO:20011412130.057
regulation of gene expressionGO:00104682650.055
regulation of protein targetingGO:190353320.055
lipid storageGO:001991510.055
carbohydrate biosynthetic processGO:001605110.053
pancreas developmentGO:0031016840.053
response to chemicalGO:00422213200.053
neuron differentiationGO:00301823530.051
positive regulation of signalingGO:0023056560.051
embryo development ending in birth or egg hatchingGO:00097922710.051
organonitrogen compound metabolic processGO:1901564740.051
Mouse
nuclear transportGO:005116940.051
eye morphogenesisGO:00485921440.050
gene expressionGO:00104672520.050
regulation of developmental processGO:00507932470.049
cell morphogenesisGO:00009022890.049
regulation of cell communicationGO:00106462320.048
positive regulation of developmental processGO:0051094500.048
regulation of cellular biosynthetic processGO:00313262450.047
protein importGO:001703830.045
cellular response to organic substanceGO:00713101050.045
muscle structure developmentGO:00610611960.045
Worm
macromolecular complex subunit organizationGO:0043933740.045
Worm
single organism metabolic processGO:00447102170.044
Mouse
transcription dna templatedGO:00063511810.043
establishment of localizationGO:00512342440.043
response to foodGO:003209410.041
regulation of cellular amine metabolic processGO:003323800.041
positive regulation of transcription dna templatedGO:0045893570.041
regulation of transcription from rna polymerase ii promoterGO:00063571140.041
regulation of macromolecule metabolic processGO:00602553170.041
gland developmentGO:00487321430.040
localization of cellGO:00516742440.040
protein import into nucleusGO:000660630.040
regulation of metabolic processGO:00192223590.040
cellular response to steroid hormone stimulusGO:0071383310.040
fatty acid transportGO:001590810.039
regulation of protein transportGO:005122330.039
cellular macromolecule biosynthetic processGO:00346452240.039
positive regulation of biological processGO:00485182530.039
liver developmentGO:0001889960.039
protein localization to plasma membraneGO:007265910.038
locomotionGO:00400113130.038
transportGO:00068102200.038
cellular component movementGO:00069283350.038
positive regulation of cell substrate adhesionGO:001081110.037
eye developmentGO:00016542770.037
regulation of organ growthGO:004662030.037
digestive system developmentGO:00551232890.037
cellular amino acid metabolic processGO:000652070.037
Mouse
protein metabolic processGO:00195381830.037
regulation of cellular macromolecule biosynthetic processGO:20001122220.036
cellular component morphogenesisGO:00329893360.035
Worm
stem cell differentiationGO:00488631170.035
regulation of chemotaxisGO:0050920180.035
regulation of transcription dna templatedGO:00063552130.035
morphogenesis of an epitheliumGO:00020093330.035
stem cell proliferationGO:007208940.035
response to stressGO:00069502630.035
cell projection morphogenesisGO:00488582440.035
cellular amino acid biosynthetic processGO:000865220.034
catechol containing compound biosynthetic processGO:000971320.034
regulation of cellular metabolic processGO:00313233200.034
cell substrate adhesionGO:003158940.034
regulation of reactive oxygen species metabolic processGO:200037720.034
chemotaxisGO:00069351040.034
cellular response to lipidGO:0071396390.034
cellular catabolic processGO:0044248270.033
signal transductionGO:00071654550.033
regulation of growthGO:0040008420.033
peptidyl serine modificationGO:001820920.033
bmp signaling pathwayGO:0030509520.033
nucleobase containing compound metabolic processGO:00061392740.032
regulation of glucose importGO:004632410.032
response to organic substanceGO:00100331530.032
positive regulation of cell adhesionGO:004578510.032
regulation of nucleobase containing compound metabolic processGO:00192192500.032
protein homooligomerizationGO:005126030.032
positive regulation of catabolic processGO:000989640.032
cell motilityGO:00488702440.031
hormone transportGO:000991420.031
regulation of primary metabolic processGO:00800903110.031
organic substance biosynthetic processGO:19015762890.030
cartilage developmentGO:0051216960.030
response to endogenous stimulusGO:0009719830.030
negative regulation of nitrogen compound metabolic processGO:0051172590.030
rna biosynthetic processGO:00327741810.030
negative regulation of cellular processGO:00485232830.029
ear developmentGO:00435831270.029
regulation of signalingGO:00230512350.029
positive regulation of response to stimulusGO:0048584800.029
insulin like growth factor receptor signaling pathwayGO:004800940.028
regulation of synaptic growth at neuromuscular junctionGO:000858210.028
cell morphogenesis involved in neuron differentiationGO:00486671630.028
intracellular transportGO:0046907320.028
camera type eye developmentGO:00430102220.028
regulation of stem cell proliferationGO:007209120.027
nuclear importGO:005117030.027
response to external stimulusGO:00096052640.027
response to drugGO:004249330.027
cellular response to hormone stimulusGO:0032870390.026
rhythmic processGO:0048511210.026
neuroblast proliferationGO:000740520.026
regulation of sodium ion transportGO:000202820.026
striated muscle cell differentiationGO:00511461290.026
Worm
response to estrogenGO:0043627270.026
positive regulation of map kinase activityGO:004340630.026
endocardial cushion formationGO:000327220.025
cellular respirationGO:004533330.025
response to abiotic stimulusGO:00096281220.025
protein localization to nucleusGO:003450430.025
craniofacial suture morphogenesisGO:009709420.025
blood vessel morphogenesisGO:00485142160.025
brain developmentGO:00074202930.025
negative regulation of macromolecule metabolic processGO:0010605760.025
single organism nuclear importGO:190259330.025
response to vitaminGO:003327330.025
regulation of signal transductionGO:00099662250.025
cellular response to xenobiotic stimulusGO:0071466350.025
regulation of cellular amino acid metabolic processGO:000652100.025
regulation of dna replicationGO:000627530.025
reactive oxygen species biosynthetic processGO:190340910.024
axonogenesisGO:00074091520.024
regulation of metal ion transportGO:001095940.024
dopamine metabolic processGO:004241720.024
digestive tract developmentGO:00485652650.023
positive regulation of cell communicationGO:0010647560.023
positive regulation of cellular catabolic processGO:003133130.023
regulation of circadian rhythmGO:004275240.023
long chain fatty acid transportGO:001590910.023
regulation of cell substrate adhesionGO:001081010.023
nitric oxide metabolic processGO:004620920.023
serotonin metabolic processGO:004242810.023
embryonic heart tube developmentGO:00350501330.023
head developmentGO:00603223030.023
regulation of dendrite developmentGO:005077330.023
phagocytosisGO:000690930.023
adult behaviorGO:003053420.023
nucleocytoplasmic transportGO:000691340.023
regulation of developmental growthGO:0048638380.022
negative regulation of small gtpase mediated signal transductionGO:005105810.022
cellular component maintenanceGO:004395430.022
cell surface receptor signaling pathwayGO:00071663250.022
autophagyGO:000691440.022
regulation of behaviorGO:0050795240.022
cell proliferationGO:0008283800.021
secondary metabolic processGO:001974830.021
tube morphogenesisGO:00352393490.021
catecholamine biosynthetic processGO:004242320.021
fatty acid beta oxidationGO:000663510.021
muscle organ developmentGO:00075171010.021
peptidyl serine phosphorylationGO:001810510.021
regulation of response to external stimulusGO:0032101310.021
tissue migrationGO:0090130370.021
protein complex subunit organizationGO:0071822460.021
Worm
pathway restricted smad protein phosphorylationGO:006038910.021
primary amino compound metabolic processGO:190116010.021
cell matrix adhesionGO:000716040.021
ear morphogenesisGO:0042471640.021
vestibular receptor cell differentiationGO:006011430.021
hatchingGO:003518840.021
hindbrain developmentGO:0030902910.020
cellular protein metabolic processGO:00442671290.020
neuron projection extensionGO:1990138450.020
organism emergence from protective structureGO:007168440.020
secondary metabolite biosynthetic processGO:004455010.020
regulation of cell differentiationGO:00455951420.020
axon developmentGO:00615641660.020
guanosine containing compound metabolic processGO:190106840.020
cellular component biogenesisGO:00440851780.020
Worm
positive regulation of cellular metabolic processGO:0031325940.020
regulation of localizationGO:00328791040.020
negative regulation of ras protein signal transductionGO:004658010.019
cell growthGO:0016049570.019
regulation of glucose transportGO:001082710.019
multi organism processGO:00517041340.019
extracellular structure organizationGO:0043062270.019
positive regulation of gene expressionGO:0010628710.019
response to xenobiotic stimulusGO:0009410450.019
regulation of biomineral tissue developmentGO:007016720.019
positive regulation of biosynthetic processGO:0009891680.019
regulation of cell motilityGO:2000145460.019
cellular aldehyde metabolic processGO:000608140.019
behaviorGO:0007610740.019
positive regulation of cellular component biogenesisGO:004408930.019
extracellular matrix assemblyGO:008502910.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.018
cellular macromolecule metabolic processGO:00442603910.018
cell cycle g1 s phase transitionGO:004484310.018
regulation of reproductive processGO:200024140.018
negative regulation of neural precursor cell proliferationGO:200017810.018
neuron projection developmentGO:00311751800.018
ion transportGO:00068111140.018
regulation of cellular ketone metabolic processGO:001056570.018
cell deathGO:00082191210.018
positive regulation of nucleobase containing compound metabolic processGO:0045935690.018
lipid catabolic processGO:001604240.017
angiogenesisGO:00015251580.017
positive regulation of glucose importGO:004632610.017
melanin metabolic processGO:000658220.017
activation of mapk activityGO:000018730.017
hard palate developmentGO:006002240.017
blood coagulationGO:0007596120.017
regulation of cell projection organizationGO:0031344440.017
response to organic cyclic compoundGO:0014070510.017
chordate embryonic developmentGO:00430092710.017
cell projection organizationGO:00300302840.016
positive regulation of nucleic acid templated transcriptionGO:1903508570.016
fin developmentGO:0033333770.016
negative regulation of dna metabolic processGO:005105340.016
negative regulation of developmental processGO:0051093650.016
positive regulation of nitrogen compound metabolic processGO:0051173690.016
protein complex biogenesisGO:0070271300.016
Worm
positive regulation of lipid metabolic processGO:004583410.016
organ regenerationGO:003110010.016
internal peptidyl lysine acetylationGO:001839320.016
negative regulation of apoptotic processGO:0043066550.016
gtp metabolic processGO:004603940.016
exocrine system developmentGO:0035272280.016
response to steroid hormoneGO:0048545350.016
neutrophil migrationGO:1990266100.016
indole containing compound metabolic processGO:004243020.016
regulation of insulin like growth factor receptor signaling pathwayGO:004356710.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
interspecies interaction between organismsGO:004441940.016
respiratory electron transport chainGO:002290420.016
regulation of nucleocytoplasmic transportGO:004682220.016
neuron developmentGO:00486662620.016
vitamin a biosynthetic processGO:003523810.015
embryonic camera type eye developmentGO:0031076290.015
response to glucocorticoidGO:005138410.015
inner ear developmentGO:00488391260.015
response to hormoneGO:0009725480.015
positive regulation of protein kinase b signalingGO:005189710.015
negative regulation of bmp signaling pathwayGO:0030514130.015
negative regulation of protein phosphorylationGO:000193340.015
endocrine pancreas developmentGO:0031018270.015
immune system processGO:00023762410.015
oocyte maturationGO:000155640.015
cardiac muscle tissue developmentGO:0048738480.015
isoprenoid biosynthetic processGO:000829970.015
branched chain amino acid metabolic processGO:000908110.015
determination of bilateral symmetryGO:00098552040.015
lateral line system developmentGO:0048925760.015
regulation of intracellular protein transportGO:003315730.015
epithelial cell migrationGO:0010631250.015
regulation of cell migrationGO:0030334400.015
cellular biogenic amine metabolic processGO:000657620.015
positive regulation of chemotaxisGO:005092150.015
negative regulation of cell differentiationGO:0045596460.014
gtp catabolic processGO:000618420.014
cation transportGO:0006812810.014
specification of symmetryGO:00097992040.014
oxidative demethylationGO:007098910.014
neuron projection morphogenesisGO:00488121610.014
response to light stimulusGO:0009416460.014
response to lipidGO:0033993600.014
vasculature developmentGO:00019442780.014
regulation of positive chemotaxisGO:005092640.014
regulation of hormone secretionGO:004688320.014
chondroitin sulfate proteoglycan metabolic processGO:005065480.014
synaptic growth at neuromuscular junctionGO:005112420.014
negative regulation of dna replicationGO:000815620.014
mitochondrial transportGO:000683920.014
positive regulation of signal transductionGO:0009967560.014
retina morphogenesis in camera type eyeGO:0060042790.014
regulation of gtpase activityGO:004308720.014
negative regulation of cell developmentGO:0010721260.013
immune system developmentGO:00025201910.013
pharyngeal system developmentGO:0060037180.013
nuclear migrationGO:000709730.013
retina development in camera type eyeGO:00600411460.013
circadian rhythmGO:0007623190.013
regenerationGO:0031099910.013
positive regulation of cellular amine metabolic processGO:003324000.013
otic vesicle formationGO:0030916270.013
regulation of cellular component movementGO:0051270550.013
stem cell maintenanceGO:001982740.013
tissue regenerationGO:0042246740.013
cellular response to estradiol stimulusGO:007139210.013
positive regulation of multicellular organismal processGO:0051240520.013
positive regulation of cellular biosynthetic processGO:0031328680.013
dopamine biosynthetic processGO:004241620.013
trabecula morphogenesisGO:006138320.013
positive regulation of cell divisionGO:005178120.013
regulation of purine nucleotide catabolic processGO:003312120.013
taxisGO:00423301090.013
establishment of blood brain barrierGO:006085620.013
lateral line developmentGO:0048882660.013
cell morphogenesis involved in differentiationGO:00009041950.013
phenol containing compound biosynthetic processGO:004618940.013
positive regulation of macromolecule biosynthetic processGO:0010557590.013
semicircular canal formationGO:006087640.013
fin regenerationGO:0031101510.013
regulation of apoptotic processGO:0042981980.013
positive regulation of rna metabolic processGO:0051254590.013
positive regulation of programmed cell deathGO:0043068290.013
positive regulation of cellular carbohydrate metabolic processGO:001067610.013
lateral inhibitionGO:004633110.013
single organism cellular localizationGO:1902580460.013
positive regulation of locomotionGO:0040017140.013
regulation of synapse assemblyGO:005196330.013
glial cell migrationGO:000834730.012
regulation of carbohydrate biosynthetic processGO:004325510.012
fat soluble vitamin metabolic processGO:000677540.012
lipid oxidationGO:003444010.012
camera type eye morphogenesisGO:00485931080.012
mesenchyme developmentGO:00604851270.012
neurotransmitter secretionGO:000726920.012
regulation of stem cell differentiationGO:200073640.012
negative regulation of cell communicationGO:0010648960.012
epidermis developmentGO:0008544480.012
hormone biosynthetic processGO:004244630.012
positive regulation of nucleotide catabolic processGO:003081310.012
blood vessel developmentGO:00015682460.012
establishment of localization in cellGO:0051649770.012
somatic muscle developmentGO:000752540.012
endocrine system developmentGO:0035270650.012
regulation of bmp signaling pathwayGO:0030510390.012
negative regulation of metabolic processGO:0009892860.012
ameboidal type cell migrationGO:00016671430.012
positive regulation of glucose transportGO:001082810.012
ion transmembrane transportGO:0034220910.012
cell fate commitmentGO:0045165990.012
actin filament organizationGO:0007015150.011
renal tubule morphogenesisGO:006133310.011
deathGO:00162651210.011
cellular hormone metabolic processGO:0034754190.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
regulation of nucleotide catabolic processGO:003081120.011
hydrogen peroxide metabolic processGO:004274320.011
regulation of protein bindingGO:004339330.011
peptidyl lysine acetylationGO:001839420.011
organelle fusionGO:004828430.011
fatty acid catabolic processGO:000906210.011
detection of stimulus involved in sensory perceptionGO:0050906210.011
reproductive processGO:0022414400.011
guanosine containing compound catabolic processGO:190106920.011
cellular protein modification processGO:00064641000.011
multicellular organismal response to stressGO:003355520.011
heart morphogenesisGO:00030071560.011
cytoskeleton organizationGO:0007010960.011
Worm
melanin biosynthetic processGO:004243810.011
diterpenoid metabolic processGO:0016101150.011
retinoid metabolic processGO:0001523150.011
programmed cell deathGO:00125011190.011
mitotic cell cycleGO:0000278640.011
positive regulation of secretionGO:005104710.011
peptidyl threonine phosphorylationGO:001810710.011
regulation of cellular carbohydrate metabolic processGO:001067540.011
cell cell signalingGO:0007267520.011
single organism membrane organizationGO:0044802200.011
oogenesisGO:0048477140.011
positive regulation of cell cycleGO:004578730.011
organic substance catabolic processGO:1901575280.011
intracellular signal transductionGO:0035556850.011
cellular carbohydrate metabolic processGO:004426240.011
regulation of wound healingGO:006104120.011
regulation of cell morphogenesisGO:0022604420.011
collagen fibril organizationGO:003019910.010
hepaticobiliary system developmentGO:0061008980.010
retinal metabolic processGO:004257430.010
skin developmentGO:0043588540.010
cellular response to endogenous stimulusGO:0071495680.010
negative regulation of response to stimulusGO:00485851040.010
exocrine pancreas developmentGO:0031017280.010
tissue remodelingGO:004877140.010
developmental cell growthGO:0048588520.010
cell part morphogenesisGO:00329902460.010
carboxylic acid biosynthetic processGO:0046394120.010
response to glucoseGO:000974930.010
negative regulation of feeding behaviorGO:200025220.010
embryonic pectoral fin morphogenesisGO:0035118240.010
cellular amide metabolic processGO:004360340.010

hgd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.188
disease of metabolismDOID:001466700.188
disease of anatomical entityDOID:700.029
nervous system diseaseDOID:86300.029
bone diseaseDOID:008000100.019
musculoskeletal system diseaseDOID:1700.019
connective tissue diseaseDOID:6500.019
physical disorderDOID:008001500.015
acquired metabolic diseaseDOID:006015800.010