Danio rerio

0 known processes

plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

(Aliases: wu:fc34a05,fc57h12,zgc:55676,wu:fc57h12,fc34a05)

plekha1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
meiotic cell cycle processGO:190304630.118
meiotic nuclear divisionGO:000712640.113
cellular amine metabolic processGO:004410620.106
meiotic chromosome segregationGO:004513230.092
cellular macromolecule metabolic processGO:00442603910.089
regulation of primary metabolic processGO:00800903110.087
aromatic compound biosynthetic processGO:00194382170.086
proteolysis involved in cellular protein catabolic processGO:005160330.083
regulation of cellular metabolic processGO:00313233200.080
regulation of erk1 and erk2 cascadeGO:007037240.061
nucleocytoplasmic transportGO:000691340.054
hematopoietic or lymphoid organ developmentGO:00485341910.053
amine metabolic processGO:000930820.051
regulation of cellular amino acid metabolic processGO:000652100.051
regulation of metabolic processGO:00192223590.051
cellular nitrogen compound metabolic processGO:00346412900.051
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.049
regulation of cellular amine metabolic processGO:003323800.049
cell migrationGO:00164772370.048
regulation of macromolecule metabolic processGO:00602553170.048
hemopoiesisGO:00300971830.047
positive regulation of catabolic processGO:000989640.047
cellular ketone metabolic processGO:0042180110.047
immune system processGO:00023762410.046
proteasomal protein catabolic processGO:001049820.044
immune system developmentGO:00025201910.044
female meiotic divisionGO:000714320.044
cellular amino acid metabolic processGO:000652070.044
negative regulation of protein phosphorylationGO:000193340.043
larval developmentGO:000216420.042
positive regulation of chromatin modificationGO:190331010.042
rna metabolic processGO:00160702190.042
cellular response to external stimulusGO:007149620.042
response to chemicalGO:00422213200.041
regulation of cellular ketone metabolic processGO:001056570.041
macromolecule modificationGO:00434121110.040
positive regulation of metabolic processGO:00098931080.040
nuclear transportGO:005116940.040
cellular component movementGO:00069283350.039
cytoskeleton dependent cytokinesisGO:006164030.039
cellular response to nutrient levelsGO:003166920.039
protein localization to plasma membraneGO:007265910.038
maintenance of locationGO:005123540.038
regulation of nucleobase containing compound metabolic processGO:00192192500.038
meiotic spindle organizationGO:000021210.037
rna biosynthetic processGO:00327741810.037
cellular nitrogen compound biosynthetic processGO:00442712180.035
agingGO:000756820.035
peptidyl threonine phosphorylationGO:001810710.035
regulation of multicellular organismal processGO:00512392770.035
oxoacid metabolic processGO:0043436310.034
positive regulation of cellular amine metabolic processGO:003324000.034
locomotionGO:00400113130.034
negative regulation of biological processGO:00485193040.033
single organism organelle organizationGO:19025891990.032
erythrocyte differentiationGO:0030218540.032
macromolecule biosynthetic processGO:00090592270.032
positive regulation of cellular catabolic processGO:003133130.032
regulation of establishment of protein localizationGO:007020140.031
multicellular organism growthGO:003526440.031
erk1 and erk2 cascadeGO:007037140.031
protein metabolic processGO:00195381830.031
cellular protein modification processGO:00064641000.031
response to external stimulusGO:00096052640.031
regulation of gene expressionGO:00104682650.030
regulation of intracellular protein transportGO:003315730.030
positive regulation of cellular processGO:00485222010.030
regulation of reproductive processGO:200024140.030
peptidyl threonine modificationGO:001821010.029
regionalizationGO:00030022740.029
modification dependent macromolecule catabolic processGO:004363230.029
regulation of localizationGO:00328791040.029
cortical actin cytoskeleton organizationGO:003086610.029
positive regulation of cellular amino acid metabolic processGO:004576400.029
cellular response to starvationGO:000926710.028
positive regulation of cellular metabolic processGO:0031325940.028
establishment of protein localization to organelleGO:007259440.028
regulation of protein catabolic processGO:004217610.028
regulation of protein ubiquitinationGO:003139630.028
meiosis iGO:000712710.028
modification dependent protein catabolic processGO:001994130.028
regulation of protein modification by small protein conjugation or removalGO:190332030.028
nucleic acid metabolic processGO:00903042440.028
phosphorylationGO:0016310690.027
cellular response to extracellular stimulusGO:003166820.027
lipid storageGO:001991510.027
positive regulation of macromolecule metabolic processGO:0010604930.027
positive regulation of nitrogen compound metabolic processGO:0051173690.027
heart developmentGO:00075073130.027
regulation of protein transportGO:005122330.027
single organism metabolic processGO:00447102170.027
ubiquitin dependent protein catabolic processGO:000651130.027
response to stressGO:00069502630.026
erythrocyte homeostasisGO:0034101550.026
cytoskeleton organizationGO:0007010960.026
positive regulation of biological processGO:00485182530.026
regulation of protein targetingGO:190353320.026
regulation of response to biotic stimulusGO:000283120.026
positive regulation of map kinase activityGO:004340630.025
response to organic substanceGO:00100331530.025
regulation of nitrogen compound metabolic processGO:00511712510.025
cellular protein catabolic processGO:004425740.025
establishment of protein localization to plasma membraneGO:009000210.025
cell motilityGO:00488702440.025
signal transductionGO:00071654550.025
organic cyclic compound biosynthetic processGO:19013622230.024
localization of cellGO:00516742440.024
single organism localizationGO:19025782250.024
regulation of response to stimulusGO:00485832690.024
gene expressionGO:00104672520.023
single organism transportGO:00447652060.023
cellular aromatic compound metabolic processGO:00067252950.023
nucleobase containing compound biosynthetic processGO:00346542050.023
primary neural tube formationGO:001402010.023
organelle fissionGO:0048285230.023
positive regulation of histone modificationGO:003105810.023
positive regulation of protein complex assemblyGO:003133420.023
positive regulation of multi organism processGO:004390230.023
mitotic cytokinesisGO:000028130.023
regulation of glucose transportGO:001082710.023
regulation of biosynthetic processGO:00098892500.022
establishment of localizationGO:00512342440.022
autophagyGO:000691440.022
intracellular signal transductionGO:0035556850.022
protein targeting to nucleusGO:004474430.022
double strand break repairGO:000630230.021
peptidyl serine phosphorylationGO:001810510.021
carboxylic acid metabolic processGO:0019752220.021
regulation of cellular biosynthetic processGO:00313262450.021
protein modification processGO:00362111000.021
regulation of cellular component organizationGO:0051128860.021
cell cycle processGO:0022402530.021
regulation of rna biosynthetic processGO:20011412130.021
organelle organizationGO:00069962270.021
cellular response to chemical stimulusGO:00708871570.021
nucleic acid templated transcriptionGO:00976591810.021
odontogenesis of dentin containing toothGO:004247510.021
regulation of oocyte developmentGO:006028130.021
positive regulation of cellular component biogenesisGO:004408930.021
b cell activationGO:004211320.021
i kappab kinase nf kappab signalingGO:000724940.021
embryonic organ developmentGO:00485683810.020
positive regulation of chromosome organizationGO:200125210.020
immune effector processGO:0002252230.020
cell surface receptor signaling pathwayGO:00071663250.020
single organism nuclear importGO:190259330.020
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.020
positive regulation of transportGO:005105020.020
response to uvGO:000941130.020
negative regulation of protein complex assemblyGO:003133310.020
heterocycle biosynthetic processGO:00181302150.020
peptidyl serine modificationGO:001820920.020
organelle fusionGO:004828430.020
cellular biosynthetic processGO:00442492860.020
regulation of cytoplasmic transportGO:190364940.020
regulation of meiotic cell cycleGO:005144510.020
chromosome organizationGO:0051276310.020
regulation of i kappab kinase nf kappab signalingGO:004312240.020
stem cell divisionGO:001714510.020
histone phosphorylationGO:001657220.020
cytokinesisGO:000091030.020
regulation of stem cell proliferationGO:007209120.020
regulation of reactive oxygen species metabolic processGO:200037720.019
transcription dna templatedGO:00063511810.019
nuclear importGO:005117030.019
regulation of cellular protein catabolic processGO:190336210.019
heterocycle metabolic processGO:00464832900.019
myeloid cell differentiationGO:0030099860.019
regulation of cell communicationGO:00106462320.019
organic substance biosynthetic processGO:19015762890.019
protein importGO:001703830.019
myeloid cell homeostasisGO:0002262560.019
centrosome organizationGO:005129710.019
production of molecular mediator of immune responseGO:000244020.019
transcription from rna polymerase ii promoterGO:0006366800.019
organic cyclic compound metabolic processGO:19013603010.019
negative regulation of cellular processGO:00485232830.018
endosomal transportGO:001619720.018
negative regulation of protein kinase activityGO:000646940.018
microtubule organizing center organizationGO:003102310.018
antimicrobial humoral responseGO:001973020.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.018
tube closureGO:006060610.018
embryonic heart tube developmentGO:00350501330.017
regulation of protein complex assemblyGO:004325430.017
regulation of defense response to virus by hostGO:005069110.017
g protein coupled receptor signaling pathwayGO:0007186740.017
apoptotic processGO:00069151160.017
positive regulation of immune effector processGO:000269930.017
positive regulation of dna metabolic processGO:005105410.017
regulation of molecular functionGO:0065009700.017
nuclear exportGO:005116810.017
regulation of signal transductionGO:00099662250.017
positive regulation of epithelial cell proliferationGO:005067910.017
rna localizationGO:000640340.017
cell cycleGO:0007049930.017
phosphate containing compound metabolic processGO:00067961080.017
stem cell proliferationGO:007208940.017
tube morphogenesisGO:00352393490.016
small molecule metabolic processGO:0044281770.016
cellular component biogenesisGO:00440851780.016
regulation of biological qualityGO:00650082630.016
myeloid cell developmentGO:0061515320.016
lymphocyte proliferationGO:004665110.016
gtp metabolic processGO:004603940.016
regulation of purine nucleotide catabolic processGO:003312120.016
purine nucleoside monophosphate catabolic processGO:000912840.016
establishment of epithelial cell polarityGO:009016220.016
female sex differentiationGO:004666040.016
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.016
regulation of synapse assemblyGO:005196330.016
regulation of glucose importGO:004632410.016
cell agingGO:000756920.016
cellular response to endogenous stimulusGO:0071495680.016
regulation of cellular protein metabolic processGO:0032268520.016
positive regulation of small gtpase mediated signal transductionGO:005105710.016
reciprocal dna recombinationGO:003582510.016
activation of mapk activityGO:000018730.016
regulation of protein localization to nucleusGO:190018020.016
regulation of production of molecular mediator of immune responseGO:000270010.016
regulation of programmed cell deathGO:00430671010.016
germ line stem cell maintenanceGO:003071820.015
regulation of anatomical structure morphogenesisGO:00226031300.015
transportGO:00068102200.015
positive regulation of i kappab kinase nf kappab signalingGO:004312330.015
anterior posterior pattern specificationGO:00099521520.015
lipid catabolic processGO:001604240.015
regulation of protein metabolic processGO:0051246560.015
regulation of nucleoside metabolic processGO:000911820.015
erythrocyte developmentGO:0048821240.015
regulation of nucleocytoplasmic transportGO:004682220.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
regulation of multicellular organismal developmentGO:20000262230.015
positive regulation of cell divisionGO:005178120.015
mononuclear cell proliferationGO:003294310.015
protein complex subunit organizationGO:0071822460.015
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.015
regulation of transcription dna templatedGO:00063552130.015
regulation of carbohydrate metabolic processGO:000610940.015
transmembrane transportGO:00550851200.015
regulation of cytokine productionGO:000181730.015
regulation of nucleic acid templated transcriptionGO:19035062130.015
regulation of protein import into nucleusGO:004230620.015
organonitrogen compound metabolic processGO:1901564740.015
membrane fusionGO:006102520.014
nik nf kappab signalingGO:003806110.014
regulation of defense response to virusGO:005068820.014
carbohydrate biosynthetic processGO:001605110.014
protein phosphorylationGO:0006468470.014
regulation of blood pressureGO:000821710.014
positive regulation of camp biosynthetic processGO:003081920.014
regulation of synapse organizationGO:005080730.014
negative regulation of protein serine threonine kinase activityGO:007190120.014
internal protein amino acid acetylationGO:000647520.014
positive regulation of canonical wnt signaling pathwayGO:009026340.014
chromatin modificationGO:0016568210.014
glucose importGO:004632320.014
vasculature developmentGO:00019442780.014
positive regulation of cytokine productionGO:000181920.014
regulation of organ growthGO:004662030.014
biosynthetic processGO:00090582940.014
regulation of locomotionGO:0040012550.014
positive regulation of oocyte developmentGO:006028210.014
nitrogen compound metabolic processGO:00068073190.014
regulation of jun kinase activityGO:004350630.014
positive regulation of camp metabolic processGO:003081620.014
centrosome duplicationGO:005129810.014
exocytosisGO:000688710.014
negative regulation of map kinase activityGO:004340720.013
cell cycle g1 s phase transitionGO:004484310.013
positive regulation of embryonic developmentGO:004001930.013
rna 3 end processingGO:003112320.013
growthGO:00400071740.013
positive regulation of jun kinase activityGO:004350720.013
reactive nitrogen species metabolic processGO:200105700.013
homeostasis of number of cellsGO:0048872620.013
cellular response to light stimulusGO:007148240.013
protein polymerizationGO:005125840.013
g2 dna damage checkpointGO:003157230.013
nuclear divisionGO:0000280230.013
regulation of neural precursor cell proliferationGO:200017730.013
centrosome cycleGO:000709810.013
central nervous system developmentGO:00074173870.013
negative regulation of catabolic processGO:000989530.013
histone modificationGO:0016570200.013
cellular response to organic substanceGO:00713101050.013
regulation of systemic arterial blood pressureGO:000307310.013
negative regulation of cellular catabolic processGO:003133030.013
spermatid developmentGO:000728620.013
regulation of chromosome segregationGO:005198310.013
medulla oblongata developmentGO:002155040.013
protein import into nucleusGO:000660630.013
response to nutrientGO:000758430.013
regulation of signalingGO:00230512350.013
regulation of bindingGO:005109830.013
cellular protein metabolic processGO:00442671290.013
ion transmembrane transportGO:0034220910.013
neuroblast proliferationGO:000740520.013
negative regulation of kinase activityGO:003367340.013
response to monosaccharideGO:003428430.013
blood vessel developmentGO:00015682460.013
cellular amide metabolic processGO:004360340.012
leukocyte proliferationGO:007066110.012
regulation of cellular component movementGO:0051270550.012
positive regulation of ras protein signal transductionGO:004657910.012
head developmentGO:00603223030.012
cellular respirationGO:004533330.012
protein targeting to membraneGO:000661210.012
nephron epithelium morphogenesisGO:007208810.012
b cell differentiationGO:003018310.012
developmental programmed cell deathGO:001062340.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
negative regulation of gene expressionGO:0010629650.012
positive regulation of apoptotic processGO:0043065290.012
homeostatic processGO:00425921420.012
somatic stem cell maintenanceGO:003501910.012
polarized epithelial cell differentiationGO:003085940.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
regulation of cell shapeGO:000836010.012
apoptotic process involved in developmentGO:190274220.012
microtubule cytoskeleton organizationGO:0000226330.012
g1 s transition of mitotic cell cycleGO:000008210.012
endocrine processGO:005088620.012
telomere maintenanceGO:000072310.012
hormone transportGO:000991420.012
microtubule cytoskeleton organization involved in mitosisGO:190285010.012
nephron tubule morphogenesisGO:007207810.012
positive regulation of erk1 and erk2 cascadeGO:007037420.012
dorsal motor nucleus of vagus nerve developmentGO:002174440.012
regulation of stem cell differentiationGO:200073640.012
regulation of epithelial to mesenchymal transitionGO:001071730.012
organic acid metabolic processGO:0006082310.012
regulation of cell differentiationGO:00455951420.012
single organism membrane fusionGO:004480120.012
chemosensory behaviorGO:000763510.012
peptidyl lysine acetylationGO:001839420.012
actin filament based processGO:0030029640.012
covalent chromatin modificationGO:0016569200.012
renal tubule morphogenesisGO:006133310.012
spindle assembly involved in mitosisGO:009030710.012
regulation of macromolecule biosynthetic processGO:00105562250.012
protein polyubiquitinationGO:000020940.012
negative regulation of defense responseGO:003134820.012
hindbrain developmentGO:0030902910.012
ion transportGO:00068111140.012
nuclear migrationGO:000709730.012
regulation of hormone secretionGO:004688320.012
mrna 3 end processingGO:003112420.012
adherens junction organizationGO:003433240.012
regulation of jak stat cascadeGO:004642530.012
adherens junction maintenanceGO:003433420.011
cellular component disassemblyGO:002241110.011
positive regulation of protein polymerizationGO:003227320.011
chromatin organizationGO:0006325220.011
regulation of catalytic activityGO:0050790550.011
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.011
osteoclast differentiationGO:003031610.011
regulation of alternative mrna splicing via spliceosomeGO:000038110.011
actin cytoskeleton organizationGO:0030036630.011
macroautophagyGO:001623610.011
negative regulation of secretion by cellGO:190353120.011
programmed cell deathGO:00125011190.011
cortical cytoskeleton organizationGO:003086510.011
cell deathGO:00082191210.011
stem cell maintenanceGO:001982740.011
regulation of intracellular signal transductionGO:1902531570.011
negative regulation of nuclear divisionGO:005178430.011
cellular response to stressGO:0033554620.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
regulation of nucleotide catabolic processGO:003081120.011
negative regulation of mapk cascadeGO:004340940.011
regulation of inflammatory responseGO:005072720.011
positive regulation of cell cycleGO:004578730.011
synaptic growth at neuromuscular junctionGO:005112420.011
regulation of multicellular organism growthGO:004001440.011
regulation of apoptotic processGO:0042981980.011
generation of neuronsGO:00486993850.011
response to biotic stimulusGO:0009607970.011
positive regulation of defense response to virus by hostGO:000223000.011
gtp catabolic processGO:000618420.011
regulation of protein localization to plasma membraneGO:190307610.011
regulation of growth rateGO:004000910.011
positive regulation of nucleotide catabolic processGO:003081310.011
positive regulation of jnk cascadeGO:004633030.011
positive regulation of transcription dna templatedGO:0045893570.011
regulation of response to cytokine stimulusGO:006075930.011
telomere organizationGO:003220010.011
heart loopingGO:0001947940.011
nucleobase containing compound metabolic processGO:00061392740.011
regulation of gtpase activityGO:004308720.011
regulation of cellular macromolecule biosynthetic processGO:20001122220.011
compound eye developmentGO:004874920.011
camera type eye morphogenesisGO:00485931080.011
negative chemotaxisGO:005091910.011
protein localization to nucleusGO:003450430.011
neurotransmitter transportGO:000683620.011
negative regulation of multi organism processGO:004390130.011
cell death in response to oxidative stressGO:003647320.011
er nucleus signaling pathwayGO:000698420.010
spermatid differentiationGO:004851520.010
negative regulation of i kappab kinase nf kappab signalingGO:004312410.010
brain developmentGO:00074202930.010
regulation of developmental processGO:00507932470.010
peptide metabolic processGO:000651810.010
chordate embryonic developmentGO:00430092710.010
spindle assemblyGO:005122520.010
regulation of rna metabolic processGO:00512522240.010
organic substance transportGO:0071702580.010
nucleoside monophosphate catabolic processGO:000912540.010
cellular response to biotic stimulusGO:007121630.010
oocyte maturationGO:000155640.010
vacuolar transportGO:000703420.010
golgi vesicle transportGO:004819330.010
hormone secretionGO:004687920.010
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.010
specification of axis polarityGO:006500140.010
regulation of cytokine biosynthetic processGO:004203510.010
proteolysisGO:0006508380.010
cellular component morphogenesisGO:00329893360.010
regulation of cell motilityGO:2000145460.010

plekha1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.044
immune system diseaseDOID:291400.020
nervous system diseaseDOID:86300.018
musculoskeletal system diseaseDOID:1700.012