Danio rerio

0 known processes

plekha8

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8

(Aliases: wu:fc68b04,zgc:101886)

plekha8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.066
agingGO:000756820.051
organelle fusionGO:004828430.047
endosomal transportGO:001619720.045
phagocytosisGO:000690930.042
positive regulation of transportGO:005105020.039
cognitionGO:005089010.039
multicellular organism growthGO:003526440.037
cytokinesisGO:000091030.036
exocytosisGO:000688710.034
establishment of protein localization to organelleGO:007259440.033
single organism membrane fusionGO:004480120.031
regulation of multicellular organism growthGO:004001440.031
ubiquitin dependent protein catabolic processGO:000651130.031
cellular macromolecule metabolic processGO:00442603910.030
membrane fusionGO:006102520.030
modification dependent macromolecule catabolic processGO:004363230.030
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.030
modification dependent protein catabolic processGO:001994130.029
golgi vesicle transportGO:004819330.029
proteolysis involved in cellular protein catabolic processGO:005160330.028
meiotic nuclear divisionGO:000712640.028
nucleocytoplasmic transportGO:000691340.027
amine metabolic processGO:000930820.027
maintenance of locationGO:005123540.027
proteasomal protein catabolic processGO:001049820.027
regulation of metal ion transportGO:001095940.027
autophagyGO:000691440.026
cellular response to external stimulusGO:007149620.026
cellular protein catabolic processGO:004425740.026
cellular amine metabolic processGO:004410620.025
signal transductionGO:00071654550.025
nuclear transportGO:005116940.025
synaptic growth at neuromuscular junctionGO:005112420.025
guanosine containing compound metabolic processGO:190106840.024
cytoskeleton dependent cytokinesisGO:006164030.024
heterocycle metabolic processGO:00464832900.024
regulation of cytokine productionGO:000181730.024
regulation of protein complex assemblyGO:004325430.024
nitrogen compound metabolic processGO:00068073190.023
mitochondrion organizationGO:000700540.023
response to chemicalGO:00422213200.023
positive regulation of cellular component biogenesisGO:004408930.023
regulation of metabolic processGO:00192223590.023
positive regulation of cell cycleGO:004578730.023
regulation of bindingGO:005109830.023
neuron differentiationGO:00301823530.022
guanosine containing compound catabolic processGO:190106920.022
positive regulation of catabolic processGO:000989640.022
regulation of synapse organizationGO:005080730.022
negative regulation of cellular processGO:00485232830.022
neuron neuron synaptic transmissionGO:000727010.022
cellular response to nutrient levelsGO:003166920.022
generation of neuronsGO:00486993850.022
regulation of protein transportGO:005122330.022
regulation of cellular amino acid metabolic processGO:000652100.022
protein localization to nucleusGO:003450430.021
regulation of cellular amine metabolic processGO:003323800.021
gtp metabolic processGO:004603940.021
rna localizationGO:000640340.021
lipid storageGO:001991510.021
gene expressionGO:00104672520.021
extrinsic apoptotic signaling pathwayGO:009719130.021
meiotic cell cycle processGO:190304630.021
protein acetylationGO:000647320.021
response to stressGO:00069502630.021
response to drugGO:004249330.021
adult behaviorGO:003053420.021
gtp catabolic processGO:000618420.020
positive regulation of cellular catabolic processGO:003133130.020
cellular component morphogenesisGO:00329893360.020
transportGO:00068102200.020
Human
regulation of establishment of protein localizationGO:007020140.020
negative regulation of protein phosphorylationGO:000193340.020
protein importGO:001703830.020
lateral inhibitionGO:004633110.020
morphogenesis of an epitheliumGO:00020093330.020
cellular biosynthetic processGO:00442492860.020
cell part morphogenesisGO:00329902460.020
protein localization to plasma membraneGO:007265910.020
regulation of synaptic plasticityGO:004816710.020
stem cell proliferationGO:007208940.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
cellular nitrogen compound metabolic processGO:00346412900.020
i kappab kinase nf kappab signalingGO:000724940.020
regulation of synapse assemblyGO:005196330.019
cellular amide metabolic processGO:004360340.019
single organism nuclear importGO:190259330.019
regulation of macromolecule metabolic processGO:00602553170.019
regulation of protein ubiquitinationGO:003139630.019
cellular amino acid metabolic processGO:000652070.019
synaptic vesicle localizationGO:009747910.019
negative regulation of biological processGO:00485193040.019
cellular response to extracellular stimulusGO:003166820.019
regulation of dendrite developmentGO:005077330.019
regulation of cellular ketone metabolic processGO:001056570.019
establishment of localizationGO:00512342440.019
Human
regulation of cellular biosynthetic processGO:00313262450.019
regulation of primary metabolic processGO:00800903110.019
regulation of cell shapeGO:000836010.019
single organism transportGO:00447652060.019
Human
nucleic acid metabolic processGO:00903042440.019
regulation of cytoplasmic transportGO:190364940.019
nucleobase containing compound metabolic processGO:00061392740.019
cellular component movementGO:00069283350.019
synaptic vesicle transportGO:004848910.019
ribonucleoside monophosphate catabolic processGO:000915840.019
cell substrate adhesionGO:003158940.018
stem cell maintenanceGO:001982740.018
regulation of cellular metabolic processGO:00313233200.018
regulation of synaptic growth at neuromuscular junctionGO:000858210.018
cellular carbohydrate metabolic processGO:004426240.018
neuroblast proliferationGO:000740520.018
protein acylationGO:004354330.018
single organism metabolic processGO:00447102170.018
immune system processGO:00023762410.018
macromolecule biosynthetic processGO:00090592270.018
peptidyl lysine acetylationGO:001839420.018
cell morphogenesisGO:00009022890.018
neurotransmitter transportGO:000683620.018
protein targeting to nucleusGO:004474430.018
organic substance biosynthetic processGO:19015762890.018
biosynthetic processGO:00090582940.018
carboxylic acid metabolic processGO:0019752220.018
regulation of response to stimulusGO:00485832690.018
organic cyclic compound metabolic processGO:19013603010.018
central nervous system developmentGO:00074173870.018
cell projection morphogenesisGO:00488582440.018
internal protein amino acid acetylationGO:000647520.017
organonitrogen compound metabolic processGO:1901564740.017
compound eye developmentGO:004874920.017
cellular ketone metabolic processGO:0042180110.017
peptidyl serine modificationGO:001820920.017
regulation of signalingGO:00230512350.017
negative regulation of protein kinase activityGO:000646940.017
regulation of intracellular protein transportGO:003315730.017
regulation of purine nucleotide catabolic processGO:003312120.017
rna metabolic processGO:00160702190.017
organic acid metabolic processGO:0006082310.017
cell surface receptor signaling pathwayGO:00071663250.017
cell projection organizationGO:00300302840.017
regulation of reproductive processGO:200024140.017
nucleoside monophosphate catabolic processGO:000912540.017
purine ribonucleoside monophosphate catabolic processGO:000916940.017
establishment of synaptic vesicle localizationGO:009748010.017
negative regulation of catabolic processGO:000989530.017
regulation of nucleotide catabolic processGO:003081120.017
response to external stimulusGO:00096052640.017
single organism localizationGO:19025782250.017
Human
negative regulation of kinase activityGO:003367340.017
regulation of cell activationGO:005086510.017
sensory organ developmentGO:00074233930.017
protein metabolic processGO:00195381830.017
nuclear importGO:005117030.017
chordate embryonic developmentGO:00430092710.017
organelle organizationGO:00069962270.017
tube morphogenesisGO:00352393490.017
regulation of sequestering of calcium ionGO:005128240.017
sequestering of calcium ionGO:005120830.017
oxoacid metabolic processGO:0043436310.017
regulation of protein catabolic processGO:004217610.017
regulation of cell communicationGO:00106462320.016
embryonic organ developmentGO:00485683810.016
positive regulation of immune effector processGO:000269930.016
regulation of autophagyGO:001050630.016
tissue remodelingGO:004877140.016
protein secretionGO:000930610.016
regulation of nucleoside metabolic processGO:000911820.016
regulation of erk1 and erk2 cascadeGO:007037240.016
cell migrationGO:00164772370.016
regulation of mrna processingGO:005068430.016
chemosensory behaviorGO:000763510.016
cellular component disassemblyGO:002241110.016
positive regulation of secretion by cellGO:190353210.016
organic acid catabolic processGO:001605430.016
internal peptidyl lysine acetylationGO:001839320.016
microtubule organizing center organizationGO:003102310.016
regulation of i kappab kinase nf kappab signalingGO:004312240.016
cellular aromatic compound metabolic processGO:00067252950.016
peptidyl serine phosphorylationGO:001810510.016
regulation of protein targetingGO:190353320.016
atp catabolic processGO:000620040.016
spermatid differentiationGO:004851520.016
regulation of nitrogen compound metabolic processGO:00511712510.016
spermatid developmentGO:000728620.016
locomotor rhythmGO:004547530.016
cellular response to starvationGO:000926710.016
carboxylic acid catabolic processGO:004639530.016
regulation of stem cell proliferationGO:007209120.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
positive regulation of protein complex assemblyGO:003133420.016
cellular response to biotic stimulusGO:007121630.016
positive regulation of cellular amine metabolic processGO:003324000.016
negative regulation of sequestering of calcium ionGO:005128340.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
nucleobase containing compound biosynthetic processGO:00346542050.015
positive regulation of secretionGO:005104710.015
transcription dna templatedGO:00063511810.015
single fertilizationGO:000733830.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.015
leukocyte proliferationGO:007066110.015
peptide metabolic processGO:000651810.015
heterocycle biosynthetic processGO:00181302150.015
regulation of multicellular organismal processGO:00512392770.015
organic cyclic compound biosynthetic processGO:19013622230.015
positive regulation of cytokine productionGO:000181920.015
small molecule metabolic processGO:0044281770.015
cytoplasm organizationGO:000702840.015
meiotic chromosome segregationGO:004513230.015
regulation of gene expressionGO:00104682650.015
regulation of biosynthetic processGO:00098892500.015
secondary metabolic processGO:001974830.015
regulation of nucleocytoplasmic transportGO:004682220.015
immune system developmentGO:00025201910.015
positive regulation of nucleoside metabolic processGO:004597910.015
protein dephosphorylationGO:000647030.015
regulation of extrinsic apoptotic signaling pathwayGO:200123630.015
cell motilityGO:00488702440.015
regulation of biological qualityGO:00650082630.015
response to uvGO:000941130.015
purine nucleoside monophosphate catabolic processGO:000912840.015
erk1 and erk2 cascadeGO:007037140.015
neurotransmitter secretionGO:000726920.015
regulation of developmental processGO:00507932470.015
regulation of neurotransmitter transportGO:005158810.014
negative regulation of cellular catabolic processGO:003133030.014
nucleic acid templated transcriptionGO:00976591810.014
regulation of signal transductionGO:00099662250.014
cellular nitrogen compound biosynthetic processGO:00442712180.014
response to monosaccharideGO:003428430.014
neuron developmentGO:00486662620.014
calcium ion transport into cytosolGO:006040230.014
sequestering of metal ionGO:005123830.014
protein polyubiquitinationGO:000020940.014
production of molecular mediator of immune responseGO:000244020.014
phagocytosis engulfmentGO:000691110.014
positive regulation of cytosolic calcium ion concentrationGO:000720440.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
hemopoiesisGO:00300971830.014
regulation of protein localization to nucleusGO:190018020.014
cortical cytoskeleton organizationGO:003086510.014
alcohol biosynthetic processGO:004616520.014
primary neural tube formationGO:001402010.014
regulation of dendrite morphogenesisGO:004881430.014
adherens junction organizationGO:003433240.014
positive regulation of purine nucleotide catabolic processGO:003312310.014
head developmentGO:00603223030.014
aromatic compound biosynthetic processGO:00194382170.014
regulation of rna metabolic processGO:00512522240.014
response to alkaloidGO:004327920.014
growthGO:00400071740.014
positive regulation of i kappab kinase nf kappab signalingGO:004312330.014
cellular response to molecule of bacterial originGO:007121930.014
eye developmentGO:00016542770.014
tube closureGO:006060610.014
negative regulation of protein transportGO:005122430.014
macromolecular complex disassemblyGO:003298410.014
regulation of gtpase activityGO:004308720.014
protein import into nucleusGO:000660630.014
vacuolar transportGO:000703420.014
intracellular mrna localizationGO:000829810.014
positive regulation of dna metabolic processGO:005105410.013
regulation of transporter activityGO:003240920.013
establishment of protein localization to plasma membraneGO:009000210.013
regulation of neurotransmitter secretionGO:004692810.013
vasculature developmentGO:00019442780.013
positive regulation of cytoskeleton organizationGO:005149530.013
response to topologically incorrect proteinGO:003596620.013
cell morphogenesis involved in neuron differentiationGO:00486671630.013
positive regulation of cell activationGO:005086710.013
positive regulation of nucleotide catabolic processGO:003081310.013
release of sequestered calcium ion into cytosolGO:005120930.013
cellular macromolecule biosynthetic processGO:00346452240.013
cellular response to chemical stimulusGO:00708871570.013
negative regulation of intracellular transportGO:003238730.013
actin polymerization or depolymerizationGO:000815420.013
small molecule catabolic processGO:004428230.013
cellular response to lipopolysaccharideGO:007122230.013
interspecies interaction between organismsGO:004441940.013
regulation of ion transmembrane transporter activityGO:003241220.013
single organism organelle organizationGO:19025891990.013
fertilizationGO:000956630.013
post golgi vesicle mediated transportGO:000689210.013
heart developmentGO:00075073130.013
lipid catabolic processGO:001604240.013
cellular protein metabolic processGO:00442671290.013
negative regulation of cytoplasmic transportGO:190365020.013
regulation of macromolecule biosynthetic processGO:00105562250.013
neuron projection morphogenesisGO:00488121610.013
protein complex disassemblyGO:004324110.013
locomotionGO:00400113130.013
nucleic acid transportGO:005065720.013
mitotic cytokinesisGO:000028130.013
specification of symmetryGO:00097992040.013
cytosolic calcium ion transportGO:006040130.013
stem cell divisionGO:001714510.013
cellular transition metal ion homeostasisGO:004691630.013
response to organic substanceGO:00100331530.013
membrane invaginationGO:001032410.013
nuclear exportGO:005116810.013
developmental growthGO:00485891660.013
regulation of epithelial cell proliferationGO:005067830.013
positive regulation of apoptotic signaling pathwayGO:200123510.012
positive regulation of erk1 and erk2 cascadeGO:007037420.012
negative regulation of intracellular protein transportGO:009031730.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
regulation of protein import into nucleusGO:004230620.012
neuron projection developmentGO:00311751800.012
digestive system developmentGO:00551232890.012
blood vessel developmentGO:00015682460.012
regulation of meiotic cell cycleGO:005144510.012
positive regulation of biological processGO:00485182530.012
system processGO:00030081850.012
negative regulation of cytokine productionGO:000181810.012
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
homeostatic processGO:00425921420.012
regulation of jak stat cascadeGO:004642530.012
developmental programmed cell deathGO:001062340.012
development of primary female sexual characteristicsGO:004654540.012
positive regulation of gtpase activityGO:004354710.012
mitotic dna damage checkpointGO:004477340.012
regulation of exocytosisGO:001715710.012
cell cycle arrestGO:000705010.012
protein heterooligomerizationGO:005129110.012
mononuclear cell proliferationGO:003294310.012
regulation of neuronal synaptic plasticityGO:004816810.012
response to hydrogen peroxideGO:004254230.012
regulation of gtp catabolic processGO:003312420.012
cell matrix adhesionGO:000716040.012
antimicrobial humoral responseGO:001973020.012
cellular response to radiationGO:007147840.012
positive regulation of gtp catabolic processGO:003312610.012
cellular response to hypoxiaGO:007145610.012
mitotic dna integrity checkpointGO:004477440.012
positive regulation of stress activated mapk cascadeGO:003287430.012
cellular response to decreased oxygen levelsGO:003629410.012
rna biosynthetic processGO:00327741810.012
b cell activationGO:004211320.012
blood vessel morphogenesisGO:00485142160.012
regulation of multicellular organismal developmentGO:20000262230.012
macroautophagyGO:001623610.012
female sex differentiationGO:004666040.012
axon developmentGO:00615641660.012
cellular component biogenesisGO:00440851780.012
camera type eye developmentGO:00430102220.012
female meiotic divisionGO:000714320.012
response to carbohydrateGO:000974330.012
cellular response to oxygen levelsGO:007145310.012
determination of left right symmetryGO:00073681790.012
axonogenesisGO:00074091520.012
cellular component assemblyGO:00226071700.012
digestive tract developmentGO:00485652650.012
viral processGO:001603210.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
regulation of neural precursor cell proliferationGO:200017730.012
regulation of calcium ion transportGO:005192420.012
cellular respirationGO:004533330.012
regulation of response to biotic stimulusGO:000283120.012
centrosome organizationGO:005129710.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
actin filament based movementGO:003004810.011
multi organism cellular processGO:004476420.011
positive regulation of lymphocyte mediated immunityGO:000270810.011
protein polymerizationGO:005125840.011
neuromuscular synaptic transmissionGO:000727420.011
germ line stem cell maintenanceGO:003071820.011
positive regulation of leukocyte mediated immunityGO:000270510.011
positive regulation of cellular processGO:00485222010.011
cellular protein modification processGO:00064641000.011
double strand break repairGO:000630230.011
double strand break repair via homologous recombinationGO:000072410.011
signal transduction in absence of ligandGO:003803410.011
regulation of nucleobase containing compound metabolic processGO:00192192500.011
nucleobase containing compound transportGO:001593120.011
regulation of dna replicationGO:000627530.011
regulation of cellular protein catabolic processGO:190336210.011
lymphocyte proliferationGO:004665110.011
determination of bilateral symmetryGO:00098552040.011
lipid oxidationGO:003444010.011
protein homooligomerizationGO:005126030.011
fatty acid catabolic processGO:000906210.011
regulation of rna biosynthetic processGO:20011412130.011
digestive tract morphogenesisGO:00485462310.011
cell cycle g1 s phase transitionGO:004484310.011
cilium morphogenesisGO:0060271850.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
actin filament polymerizationGO:003004120.011
phosphatidylinositol mediated signalingGO:004801520.011
organism emergence from protective structureGO:007168440.011
gastrulationGO:00073692080.011
regulation of nucleic acid templated transcriptionGO:19035062130.011
somatic stem cell maintenanceGO:003501910.011
somatic muscle developmentGO:000752540.011
cellular lipid catabolic processGO:004424230.011
muscle structure developmentGO:00610611960.011
negative regulation of mapk cascadeGO:004340940.011
g2 dna damage checkpointGO:003157230.011
centrosome cycleGO:000709810.011
regulation of production of molecular mediator of immune responseGO:000270010.011
regulation of anatomical structure morphogenesisGO:00226031300.011
sleepGO:003043110.011
carbohydrate homeostasisGO:003350010.011
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.011
positive regulation of canonical wnt signaling pathwayGO:009026340.011
response to hexoseGO:000974630.011
localization of cellGO:00516742440.011
regulation of inflammatory responseGO:005072720.011
peptide transportGO:001583310.011
cortical actin cytoskeleton organizationGO:003086610.010
response to abiotic stimulusGO:00096281220.010
regionalizationGO:00030022740.010
multi organism processGO:00517041340.010
establishment of rna localizationGO:005123630.010
retina development in camera type eyeGO:00600411460.010
mitochondrial transportGO:000683920.010
regulation of mrna splicing via spliceosomeGO:004802430.010
rna 3 end processingGO:003112320.010
regulation of cell developmentGO:00602841000.010
response to nutrientGO:000758430.010
regulation of carbohydrate metabolic processGO:000610940.010
protein targeting to membraneGO:000661210.010
er to golgi vesicle mediated transportGO:000688810.010
golgi organizationGO:000703010.010
liver developmentGO:0001889960.010
oocyte anterior posterior axis specificationGO:000731440.010
regulation of cellular carbohydrate metabolic processGO:001067540.010
regulation of cell substrate adhesionGO:001081010.010
embryo development ending in birth or egg hatchingGO:00097922710.010
positive regulation of ras protein signal transductionGO:004657910.010
peptidyl threonine phosphorylationGO:001810710.010
positive regulation of cell adhesionGO:004578510.010
negative regulation of multi organism processGO:004390130.010
cellular modified amino acid metabolic processGO:000657530.010
positive regulation of chromosome organizationGO:200125210.010
response to unfolded proteinGO:000698620.010
positive regulation of map kinase activityGO:004340630.010
female gonad developmentGO:000858540.010
epithelial tube morphogenesisGO:00605621480.010
transcription from rna polymerase ii promoterGO:0006366800.010
macromolecule modificationGO:00434121110.010
cell substrate junction assemblyGO:000704420.010
regulation of circadian rhythmGO:004275240.010
glucose homeostasisGO:004259310.010
monocarboxylic acid catabolic processGO:007232930.010
regulation of stem cell differentiationGO:200073640.010
ion transportGO:00068111140.010
mitotic g2 m transition checkpointGO:004481830.010

plekha8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.047
nervous system diseaseDOID:86300.025
inherited metabolic disorderDOID:65500.021
disease of metabolismDOID:001466700.021
musculoskeletal system diseaseDOID:1700.016
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
organ system cancerDOID:005068600.014
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011
myopathyDOID:42300.011
immune system diseaseDOID:291400.011