Danio rerio

0 known processes

eif2b4

eukaryotic translation initiation factor 2B, subunit 4 delta

(Aliases: si:ch211-101l18.4,zgc:110790,wu:fb54a09)

eif2b4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.268
embryo development ending in birth or egg hatchingGO:00097922710.243
protein metabolic processGO:00195381830.189
Human
gene expressionGO:00104672520.119
Human
regulation of primary metabolic processGO:00800903110.084
Human
cytokinesisGO:000091030.080
locomotionGO:00400113130.073
single fertilizationGO:000733830.072
positive regulation of catabolic processGO:000989640.066
Human
cellular protein metabolic processGO:00442671290.065
Human
fertilizationGO:000956630.062
mitotic dna integrity checkpointGO:004477440.059
positive regulation of cellular component biogenesisGO:004408930.057
cellular macromolecule metabolic processGO:00442603910.056
Human
neuron differentiationGO:00301823530.056
organic cyclic compound metabolic processGO:19013603010.055
Human
establishment of localizationGO:00512342440.055
biosynthetic processGO:00090582940.054
Human
response to stressGO:00069502630.054
mitotic g2 m transition checkpointGO:004481830.053
small molecule metabolic processGO:0044281770.053
Human
cellular aromatic compound metabolic processGO:00067252950.049
Human
cellular macromolecule biosynthetic processGO:00346452240.048
Human
regulation of gene expressionGO:00104682650.047
agingGO:000756820.047
response to chemicalGO:00422213200.047
regulation of macromolecule metabolic processGO:00602553170.046
regulation of biosynthetic processGO:00098892500.046
nitrogen compound metabolic processGO:00068073190.045
Human
organonitrogen compound metabolic processGO:1901564740.045
Human
positive regulation of biological processGO:00485182530.044
Human
aromatic compound biosynthetic processGO:00194382170.044
positive regulation of nucleobase containing compound metabolic processGO:0045935690.043
Human
mitochondrion organizationGO:000700540.041
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.040
lateral inhibitionGO:004633110.038
macromolecule biosynthetic processGO:00090592270.038
Human
regulation of protein complex assemblyGO:004325430.038
regulation of protein modification by small protein conjugation or removalGO:190332030.037
protein secretionGO:000930610.036
gtp metabolic processGO:004603940.036
Human
cellular biosynthetic processGO:00442492860.036
Human
programmed cell deathGO:00125011190.035
sensory organ developmentGO:00074233930.035
regulation of nitrogen compound metabolic processGO:00511712510.034
Human
proteolysis involved in cellular protein catabolic processGO:005160330.033
tube morphogenesisGO:00352393490.033
cellular component movementGO:00069283350.033
mitotic g2 dna damage checkpointGO:000709530.033
cellular protein catabolic processGO:004425740.032
regulation of multicellular organism growthGO:004001440.032
nucleoside monophosphate catabolic processGO:000912540.031
nucleobase containing compound metabolic processGO:00061392740.031
Human
oxoacid metabolic processGO:0043436310.030
cell part morphogenesisGO:00329902460.030
regulation of rna biosynthetic processGO:20011412130.029
regulation of nucleoside metabolic processGO:000911820.029
Human
heterocycle metabolic processGO:00464832900.029
Human
sister chromatid cohesionGO:000706220.029
multicellular organism growthGO:003526440.029
response to topologically incorrect proteinGO:003596620.028
organic substance biosynthetic processGO:19015762890.028
Human
mitotic cell cycle processGO:1903047480.028
organic cyclic compound biosynthetic processGO:19013622230.028
positive regulation of cellular catabolic processGO:003133130.028
Human
regulation of metabolic processGO:00192223590.028
Human
cellular component morphogenesisGO:00329893360.028
mitotic cell cycleGO:0000278640.027
regulation of multicellular organismal processGO:00512392770.027
regulation of transcription dna templatedGO:00063552130.027
growthGO:00400071740.026
deathGO:00162651210.026
positive regulation of transportGO:005105020.026
macromolecule modificationGO:00434121110.026
guanosine containing compound metabolic processGO:190106840.026
Human
lipid storageGO:001991510.026
transportGO:00068102200.025
nucleic acid metabolic processGO:00903042440.025
nucleobase containing compound biosynthetic processGO:00346542050.025
apoptotic processGO:00069151160.025
positive regulation of protein complex assemblyGO:003133420.024
g2 dna damage checkpointGO:003157230.024
generation of neuronsGO:00486993850.024
response to external stimulusGO:00096052640.024
cellular component biogenesisGO:00440851780.024
regulation of developmental processGO:00507932470.024
negative regulation of biological processGO:00485193040.023
cell projection morphogenesisGO:00488582440.023
mitotic dna damage checkpointGO:004477340.023
protein acetylationGO:000647320.023
central nervous system developmentGO:00074173870.023
Human
heterocycle biosynthetic processGO:00181302150.023
cell cycle g1 s phase transitionGO:004484310.023
single organism transportGO:00447652060.023
regulation of macromolecule biosynthetic processGO:00105562250.023
regulation of protein catabolic processGO:004217610.022
cellular nitrogen compound metabolic processGO:00346412900.022
Human
single organism metabolic processGO:00447102170.022
Human
regulation of cellular protein catabolic processGO:190336210.022
regulation of cellular macromolecule biosynthetic processGO:20001122220.021
purine ribonucleoside monophosphate catabolic processGO:000916940.021
regulation of protein ubiquitinationGO:003139630.021
protein stabilizationGO:005082120.021
positive regulation of nucleoside metabolic processGO:004597910.021
Human
eye developmentGO:00016542770.021
cell morphogenesisGO:00009022890.021
positive regulation of cellular processGO:00485222010.021
Human
digestive tract morphogenesisGO:00485462310.020
negative regulation of cell communicationGO:0010648960.020
single organism localizationGO:19025782250.020
neuron projection morphogenesisGO:00488121610.020
muscle structure developmentGO:00610611960.020
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.020
maintenance of locationGO:005123540.020
regulation of nucleotide catabolic processGO:003081120.019
Human
multicellular organism reproductionGO:0032504350.019
Human
negative regulation of protein phosphorylationGO:000193340.019
organic acid metabolic processGO:0006082310.019
meiotic chromosome segregationGO:004513230.019
positive regulation of purine nucleotide catabolic processGO:003312310.019
Human
purine nucleotide metabolic processGO:0006163270.019
Human
carboxylic acid metabolic processGO:0019752220.019
positive regulation of nitrogen compound metabolic processGO:0051173690.018
Human
regulation of response to extracellular stimulusGO:003210410.018
regulation of purine nucleotide catabolic processGO:003312120.018
Human
ribonucleoside monophosphate catabolic processGO:000915840.018
positive regulation of gtpase activityGO:004354710.018
Human
neuron developmentGO:00486662620.017
g1 s transition of mitotic cell cycleGO:000008210.017
positive regulation of nucleotide catabolic processGO:003081310.017
Human
regulation of cellular biosynthetic processGO:00313262450.017
establishment of protein localization to organelleGO:007259440.017
protein modification by small protein removalGO:007064610.017
developmental programmed cell deathGO:001062340.017
axonogenesisGO:00074091520.017
regulation of nucleic acid templated transcriptionGO:19035062130.017
autophagyGO:000691440.017
nucleic acid templated transcriptionGO:00976591810.017
protein modification processGO:00362111000.017
single organism biosynthetic processGO:0044711710.017
cell deathGO:00082191210.017
cellular response to nutrient levelsGO:003166920.017
positive regulation of transcription dna templatedGO:0045893570.016
atp catabolic processGO:000620040.016
compound eye developmentGO:004874920.016
developmental growthGO:00485891660.016
nucleotide metabolic processGO:0009117280.016
Human
localization of cellGO:00516742440.016
cytoskeleton dependent cytokinesisGO:006164030.016
phagocytosisGO:000690930.016
gtp catabolic processGO:000618420.016
Human
female sex differentiationGO:004666040.016
Human
multi organism processGO:00517041340.015
meiotic nuclear divisionGO:000712640.015
regulation of cellular protein metabolic processGO:0032268520.015
internal protein amino acid acetylationGO:000647520.015
positive regulation of dna templated transcription elongationGO:003278610.015
response to alkaloidGO:004327920.015
cell surface receptor signaling pathwayGO:00071663250.015
regulation of synapse organizationGO:005080730.015
spindle assemblyGO:005122520.015
nuclear migrationGO:000709730.015
cellular protein modification processGO:00064641000.015
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.015
cell projection organizationGO:00300302840.015
positive regulation of cell cycleGO:004578730.015
morphogenesis of an epitheliumGO:00020093330.015
regulation of rna metabolic processGO:00512522240.015
regionalizationGO:00030022740.015
regulation of nucleobase containing compound metabolic processGO:00192192500.015
Human
cellular amino acid metabolic processGO:000652070.015
cell morphogenesis involved in neuron differentiationGO:00486671630.014
phosphorus metabolic processGO:00067931090.014
Human
cellular amine metabolic processGO:004410620.014
purine nucleoside monophosphate catabolic processGO:000912840.014
purine containing compound metabolic processGO:0072521290.014
Human
cellular response to chemical stimulusGO:00708871570.014
head developmentGO:00603223030.014
cellular nitrogen compound biosynthetic processGO:00442712180.014
protein acylationGO:004354330.014
somitogenesisGO:0001756870.014
regulation of meiotic cell cycleGO:005144510.014
regulation of gtpase activityGO:004308720.014
Human
transcription dna templatedGO:00063511810.014
negative regulation of cellular processGO:00485232830.014
regulation of mitotic cell cycleGO:0007346250.014
dna templated transcription elongationGO:000635430.014
ribonucleotide metabolic processGO:0009259270.014
Human
ncrna catabolic processGO:003466110.014
signal transductionGO:00071654550.014
amine metabolic processGO:000930820.014
modification dependent macromolecule catabolic processGO:004363230.013
multi organism reproductive processGO:0044703360.013
meiotic cell cycle processGO:190304630.013
system processGO:00030081850.013
Human
positive regulation of gene expressionGO:0010628710.013
cellular response to stressGO:0033554620.013
regulation of synapse assemblyGO:005196330.013
microtubule polymerization or depolymerizationGO:003110930.013
neuron projection developmentGO:00311751800.013
negative regulation of macromolecule metabolic processGO:0010605760.013
positive regulation of secretion by cellGO:190353210.013
cellular response to starvationGO:000926710.013
regulation of cell deathGO:00109411030.013
segmentationGO:0035282970.012
cellular response to extracellular stimulusGO:003166820.012
protein localization to plasma membraneGO:007265910.012
ubiquitin dependent protein catabolic processGO:000651130.012
translational initiationGO:000641330.012
Human
proteasomal protein catabolic processGO:001049820.012
regulation of chromosome segregationGO:005198310.012
regulation of dna templated transcription elongationGO:003278430.012
mitochondrion morphogenesisGO:007058420.012
cell cycleGO:0007049930.012
reproductionGO:0000003400.012
Human
positive regulation of secretionGO:005104710.012
regulation of programmed cell deathGO:00430671010.012
regulation of establishment of protein localizationGO:007020140.012
rna metabolic processGO:00160702190.012
negative regulation of metabolic processGO:0009892860.012
positive regulation of cellular biosynthetic processGO:0031328680.012
cellular response to external stimulusGO:007149620.012
regulation of gtp catabolic processGO:003312420.012
Human
regulation of cellular amino acid metabolic processGO:000652100.012
positive regulation of gtp catabolic processGO:003312610.012
Human
camera type eye developmentGO:00430102220.012
regulation of cell activationGO:005086510.012
organophosphate metabolic processGO:0019637370.011
Human
cellular response to oxygen levelsGO:007145310.011
cellular component disassemblyGO:002241110.011
regulation of cellular amine metabolic processGO:003323800.011
response to drugGO:004249330.011
synaptic growth at neuromuscular junctionGO:005112420.011
toxin transportGO:190199820.011
proteolysisGO:0006508380.011
multicellular organismal reproductive processGO:0048609350.011
Human
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
eye morphogenesisGO:00485921440.011
positive regulation of macromolecule metabolic processGO:0010604930.011
negative regulation of kinase activityGO:003367340.011
anterior posterior pattern specificationGO:00099521520.011
transmembrane transportGO:00550851200.011
regulation of cytokine productionGO:000181730.011
positive regulation of rna biosynthetic processGO:1902680570.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
developmental growth involved in morphogenesisGO:0060560860.011
alpha amino acid metabolic processGO:190160530.011
regulation of protein targetingGO:190353320.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
negative regulation of signalingGO:0023057960.011
mitotic nuclear divisionGO:0007067180.011
rrna catabolic processGO:001607510.011
regulation of multicellular organismal developmentGO:20000262230.011
regulation of signal transductionGO:00099662250.011
positive regulation of cellular metabolic processGO:0031325940.011
Human
regulation of protein metabolic processGO:0051246560.010
protein dephosphorylationGO:000647030.010
phosphate containing compound metabolic processGO:00067961080.010
Human
mitotic cell cycle phase transitionGO:004477290.010
cellular localizationGO:0051641970.010
somite developmentGO:0061053960.010
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.010
leukocyte proliferationGO:007066110.010
cell cell recognitionGO:000998810.010
transcription elongation from rna polymerase ii promoterGO:000636830.010
amino acid transportGO:000686520.010
sensory organ morphogenesisGO:00905962000.010
regulation of peptidyl tyrosine phosphorylationGO:005073010.010
regulation of extrinsic apoptotic signaling pathwayGO:200123630.010
intestinal absorptionGO:005089220.010
mitotic cytokinesisGO:000028130.010

eif2b4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.016
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.012
neuropathyDOID:87000.011
charcot marie tooth diseaseDOID:1059500.011
neuromuscular diseaseDOID:44000.011
musculoskeletal system diseaseDOID:1700.011