Danio rerio

0 known processes

eif2b1

eukaryotic translation initiation factor 2B, subunit 1 alpha

(Aliases: zgc:86660)

eif2b1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.096
agingGO:000756820.070
nitrogen compound metabolic processGO:00068073190.049
cellular macromolecule metabolic processGO:00442603910.046
signal transductionGO:00071654550.045
organic cyclic compound metabolic processGO:19013603010.042
cellular nitrogen compound metabolic processGO:00346412900.041
positive regulation of transportGO:005105020.041
multicellular organism growthGO:003526440.040
cellular component movementGO:00069283350.040
positive regulation of cellular component biogenesisGO:004408930.039
cellular response to external stimulusGO:007149620.038
cell surface receptor signaling pathwayGO:00071663250.037
cellular protein catabolic processGO:004425740.036
cellular component morphogenesisGO:00329893360.036
regulation of cytokine productionGO:000181730.034
establishment of protein localization to organelleGO:007259440.034
nuclear transportGO:005116940.033
nucleocytoplasmic transportGO:000691340.032
positive regulation of cellular catabolic processGO:003133130.032
heterocycle metabolic processGO:00464832900.032
regulation of establishment of protein localizationGO:007020140.032
cell motilityGO:00488702440.032
proteasomal protein catabolic processGO:001049820.032
regulation of protein transportGO:005122330.031
regulation of nitrogen compound metabolic processGO:00511712510.031
positive regulation of cell cycleGO:004578730.031
nucleobase containing compound metabolic processGO:00061392740.031
cellular response to extracellular stimulusGO:003166820.031
cell morphogenesisGO:00009022890.031
regulation of cellular metabolic processGO:00313233200.030
regulation of multicellular organism growthGO:004001440.030
locomotionGO:00400113130.030
central nervous system developmentGO:00074173870.030
single organism membrane fusionGO:004480120.030
immune system processGO:00023762410.030
regulation of biosynthetic processGO:00098892500.029
brain developmentGO:00074202930.029
regionalizationGO:00030022740.029
maintenance of locationGO:005123540.029
response to stressGO:00069502630.029
regulation of metabolic processGO:00192223590.029
cellular aromatic compound metabolic processGO:00067252950.029
stem cell maintenanceGO:001982740.029
regulation of primary metabolic processGO:00800903110.029
organelle fusionGO:004828430.028
phagocytosisGO:000690930.028
head developmentGO:00603223030.028
gtp metabolic processGO:004603940.028
internal protein amino acid acetylationGO:000647520.028
membrane fusionGO:006102520.028
regulation of nucleobase containing compound metabolic processGO:00192192500.028
protein localization to nucleusGO:003450430.028
cellular response to starvationGO:000926710.028
generation of neuronsGO:00486993850.028
response to external stimulusGO:00096052640.028
meiotic nuclear divisionGO:000712640.028
positive regulation of biological processGO:00485182530.027
biosynthetic processGO:00090582940.027
gene expressionGO:00104672520.027
regulation of macromolecule metabolic processGO:00602553170.027
cell migrationGO:00164772370.027
response to drugGO:004249330.027
immune system developmentGO:00025201910.027
mitochondrion organizationGO:000700540.027
localization of cellGO:00516742440.027
protein acetylationGO:000647320.027
regulation of gene expressionGO:00104682650.026
single organism nuclear importGO:190259330.026
nucleic acid templated transcriptionGO:00976591810.026
internal peptidyl lysine acetylationGO:001839320.026
hematopoietic or lymphoid organ developmentGO:00485341910.026
amine metabolic processGO:000930820.026
cellular response to nutrient levelsGO:003166920.026
protein acylationGO:004354330.025
rna biosynthetic processGO:00327741810.025
guanosine containing compound metabolic processGO:190106840.025
regulation of protein complex assemblyGO:004325430.025
regulation of rna metabolic processGO:00512522240.025
protein import into nucleusGO:000660630.025
protein targeting to nucleusGO:004474430.025
cell part morphogenesisGO:00329902460.025
modification dependent macromolecule catabolic processGO:004363230.025
single organism metabolic processGO:00447102170.025
cellular response to chemical stimulusGO:00708871570.025
positive regulation of catabolic processGO:000989640.025
heterocycle biosynthetic processGO:00181302150.024
gtp catabolic processGO:000618420.024
cell projection organizationGO:00300302840.024
stem cell proliferationGO:007208940.024
regulation of developmental processGO:00507932470.024
organic cyclic compound biosynthetic processGO:19013622230.024
negative regulation of biological processGO:00485193040.024
peptidyl lysine acetylationGO:001839420.024
aromatic compound biosynthetic processGO:00194382170.024
regulation of bindingGO:005109830.024
synaptic growth at neuromuscular junctionGO:005112420.023
vasculature developmentGO:00019442780.023
regulation of intracellular protein transportGO:003315730.023
regulation of cytoplasmic transportGO:190364940.023
regulation of protein localization to nucleusGO:190018020.023
regulation of response to stimulusGO:00485832690.023
proteolysis involved in cellular protein catabolic processGO:005160330.023
tube morphogenesisGO:00352393490.023
embryonic organ developmentGO:00485683810.023
regulation of nucleocytoplasmic transportGO:004682220.023
regulation of biological qualityGO:00650082630.023
nucleic acid metabolic processGO:00903042440.023
guanosine containing compound catabolic processGO:190106920.023
regulation of signalingGO:00230512350.023
regulation of cell activationGO:005086510.023
regulation of nucleoside metabolic processGO:000911820.023
regulation of protein targetingGO:190353320.023
ubiquitin dependent protein catabolic processGO:000651130.023
nuclear importGO:005117030.023
regulation of protein catabolic processGO:004217610.023
regulation of protein import into nucleusGO:004230620.023
neuron differentiationGO:00301823530.022
regulation of cell differentiationGO:00455951420.022
toll like receptor signaling pathwayGO:000222440.022
cellular amine metabolic processGO:004410620.022
positive regulation of secretionGO:005104710.022
rna localizationGO:000640340.022
cellular nitrogen compound biosynthetic processGO:00442712180.022
cellular biosynthetic processGO:00442492860.022
negative regulation of cellular processGO:00485232830.022
regulation of cellular biosynthetic processGO:00313262450.022
regulation of protein modification by small protein conjugation or removalGO:190332030.022
system processGO:00030081850.022
negative regulation of catabolic processGO:000989530.021
regulation of nucleic acid templated transcriptionGO:19035062130.021
regulation of purine nucleotide catabolic processGO:003312120.021
eye developmentGO:00016542770.021
lipid storageGO:001991510.021
organic acid metabolic processGO:0006082310.021
regulation of cellular amine metabolic processGO:003323800.021
cellular macromolecule biosynthetic processGO:00346452240.021
positive regulation of secretion by cellGO:190353210.021
regulation of nucleotide catabolic processGO:003081120.021
protein metabolic processGO:00195381830.021
regulation of cell shapeGO:000836010.021
cellular component disassemblyGO:002241110.021
determination of left right symmetryGO:00073681790.021
positive regulation of cell activationGO:005086710.021
i kappab kinase nf kappab signalingGO:000724940.021
autophagyGO:000691440.021
blood vessel developmentGO:00015682460.021
cytokinesisGO:000091030.020
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.020
regulation of multicellular organismal processGO:00512392770.020
nucleobase containing compound biosynthetic processGO:00346542050.020
neuron developmentGO:00486662620.020
regulation of transcription dna templatedGO:00063552130.020
regulation of production of molecular mediator of immune responseGO:000270010.020
determination of bilateral symmetryGO:00098552040.020
regulation of cell communicationGO:00106462320.020
rna metabolic processGO:00160702190.020
nuclear exportGO:005116810.020
regulation of cellular amino acid metabolic processGO:000652100.020
regulation of macromolecule biosynthetic processGO:00105562250.020
protein importGO:001703830.020
positive regulation of cellular processGO:00485222010.020
heart developmentGO:00075073130.020
production of molecular mediator of immune responseGO:000244020.020
regulation of organelle assemblyGO:190211540.020
cellular component biogenesisGO:00440851780.020
small molecule metabolic processGO:0044281770.020
regulation of rna biosynthetic processGO:20011412130.020
single organism organelle organizationGO:19025891990.020
phagocytosis engulfmentGO:000691110.020
meiotic cell cycle processGO:190304630.020
transcription from rna polymerase ii promoterGO:0006366800.020
response to chemicalGO:00422213200.020
cellular response to molecule of bacterial originGO:007121930.020
regulation of muscle contractionGO:000693730.020
sensory organ developmentGO:00074233930.020
retina development in camera type eyeGO:00600411460.019
cellular response to lipopolysaccharideGO:007122230.019
cell projection morphogenesisGO:00488582440.019
cell substrate adhesionGO:003158940.019
regulation of i kappab kinase nf kappab signalingGO:004312240.019
hemopoiesisGO:00300971830.019
embryonic organ morphogenesisGO:00485622740.019
regulation of cellular ketone metabolic processGO:001056570.019
establishment of localizationGO:00512342440.019
gastrulationGO:00073692080.019
exocytosisGO:000688710.019
regulation of signal transductionGO:00099662250.019
meiotic chromosome segregationGO:004513230.019
organic substance biosynthetic processGO:19015762890.019
oxoacid metabolic processGO:0043436310.019
protein secretionGO:000930610.019
membrane invaginationGO:001032410.019
dorsal ventral pattern formationGO:00099531250.018
post embryonic organ developmentGO:004856940.018
cellular protein metabolic processGO:00442671290.018
positive regulation of nucleotide catabolic processGO:003081310.018
growthGO:00400071740.018
morphogenesis of an epitheliumGO:00020093330.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.018
sensory organ morphogenesisGO:00905962000.018
response to monosaccharideGO:003428430.018
regulation of reproductive processGO:200024140.018
angiogenesisGO:00015251580.018
negative regulation of protein localization to nucleusGO:190018120.018
regulation of meiotic cell cycleGO:005144510.018
peptide transportGO:001583310.018
regulation of synapse assemblyGO:005196330.018
apical junction assemblyGO:004329710.018
blood vessel morphogenesisGO:00485142160.018
cell matrix adhesionGO:000716040.018
regulation of gtp catabolic processGO:003312420.018
transcription dna templatedGO:00063511810.018
transportGO:00068102200.018
positive regulation of cytoskeleton organizationGO:005149530.017
macromolecule modificationGO:00434121110.017
cellular ketone metabolic processGO:0042180110.017
lymphocyte proliferationGO:004665110.017
organonitrogen compound metabolic processGO:1901564740.017
positive regulation of purine nucleotide catabolic processGO:003312310.017
intracellular signal transductionGO:0035556850.017
cellular protein modification processGO:00064641000.017
cell cycle g1 s phase transitionGO:004484310.017
single organism localizationGO:19025782250.017
anterior posterior pattern specificationGO:00099521520.017
protein polymerizationGO:005125840.017
specification of symmetryGO:00097992040.017
cellular carbohydrate metabolic processGO:004426240.017
axonogenesisGO:00074091520.017
actin polymerization or depolymerizationGO:000815420.017
positive regulation of nucleoside metabolic processGO:004597910.017
regulation of cellular macromolecule biosynthetic processGO:20001122220.017
gland developmentGO:00487321430.017
digestive tract developmentGO:00485652650.017
regulation of mrna processingGO:005068430.017
macromolecule biosynthetic processGO:00090592270.017
cognitionGO:005089010.017
regulation of cell projection assemblyGO:006049140.017
neuron projection developmentGO:00311751800.017
axon developmentGO:00615641660.017
regulation of neural precursor cell proliferationGO:200017730.017
compound eye developmentGO:004874920.017
skeletal system developmentGO:00015011810.017
cellular response to biotic stimulusGO:007121630.016
carboxylic acid metabolic processGO:0019752220.016
protein complex disassemblyGO:004324110.016
chordate embryonic developmentGO:00430092710.016
regulation of alternative mrna splicing via spliceosomeGO:000038110.016
cell morphogenesis involved in differentiationGO:00009041950.016
homeostatic processGO:00425921420.016
digestive system developmentGO:00551232890.016
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.016
protein localization to plasma membraneGO:007265910.016
macromolecular complex disassemblyGO:003298410.016
centrosome organizationGO:005129710.016
camera type eye developmentGO:00430102220.016
response to carbohydrateGO:000974330.016
response to hexoseGO:000974630.016
b cell activationGO:004211320.016
negative regulation of nucleocytoplasmic transportGO:004682320.016
regulation of mrna splicing via spliceosomeGO:004802430.016
liver developmentGO:0001889960.016
regulation of protein bindingGO:004339330.016
regulation of protein ubiquitinationGO:003139630.016
purine ribonucleoside monophosphate catabolic processGO:000916940.016
digestive tract morphogenesisGO:00485462310.016
response to glucoseGO:000974930.016
cellular amino acid metabolic processGO:000652070.016
organelle organizationGO:00069962270.016
regulation of synaptic growth at neuromuscular junctionGO:000858210.016
dna templated transcription elongationGO:000635430.016
somatic muscle developmentGO:000752540.016
leukocyte proliferationGO:007066110.016
determination of heart left right asymmetryGO:00613711170.016
locomotor rhythmGO:004547530.016
multi organism processGO:00517041340.016
regulation of cell substrate adhesionGO:001081010.016
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.015
ribonucleoside monophosphate catabolic processGO:000915840.015
spermatid developmentGO:000728620.015
positive regulation of cytokine productionGO:000181920.015
regulation of blood pressureGO:000821710.015
negative regulation of cytokine productionGO:000181810.015
regulation of gtpase activityGO:004308720.015
single organism transportGO:00447652060.015
enzyme linked receptor protein signaling pathwayGO:00071671060.015
antimicrobial humoral responseGO:001973020.015
positive regulation of gtp catabolic processGO:003312610.015
negative regulation of protein phosphorylationGO:000193340.015
protein modification processGO:00362111000.015
regulation of reactive oxygen species metabolic processGO:200037720.015
tissue remodelingGO:004877140.015
neuroblast proliferationGO:000740520.015
regulation of cellular carbohydrate metabolic processGO:001067540.015
regulation of multicellular organismal developmentGO:20000262230.015
rna transportGO:005065820.015
positive regulation of muscle cell differentiationGO:005114910.015
female sex differentiationGO:004666040.015
cellular component assemblyGO:00226071700.015
smooth muscle contractionGO:000693920.015
carbohydrate biosynthetic processGO:001605110.015
mononuclear cell proliferationGO:003294310.015
macroautophagyGO:001623610.015
carbohydrate homeostasisGO:003350010.015
regulation of inflammatory responseGO:005072720.015
positive regulation of cell adhesionGO:004578510.015
positive regulation of cellular amine metabolic processGO:003324000.015
regulation of tube sizeGO:003515020.015
nucleoside monophosphate catabolic processGO:000912540.014
muscle structure developmentGO:00610611960.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
positive regulation of translationGO:004572710.014
cellular localizationGO:0051641970.014
mitotic dna integrity checkpointGO:004477440.014
adult behaviorGO:003053420.014
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.014
hepaticobiliary system developmentGO:0061008980.014
positive regulation of protein complex assemblyGO:003133420.014
positive regulation of immune effector processGO:000269930.014
regulation of dna templated transcription elongationGO:003278430.014
modification dependent protein catabolic processGO:001994130.014
atp catabolic processGO:000620040.014
stem cell divisionGO:001714510.014
inner ear developmentGO:00488391260.014
positive regulation of gtpase activityGO:004354710.014
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.014
ear developmentGO:00435831270.014
regulation of synapse organizationGO:005080730.014
regulation of carbohydrate metabolic processGO:000610940.014
negative regulation of protein import into nucleusGO:004230820.014
extrinsic apoptotic signaling pathwayGO:009719130.014
response to woundingGO:00096111160.014
response to organic substanceGO:00100331530.014
positive regulation of nitrogen compound metabolic processGO:0051173690.014
chemosensory behaviorGO:000763510.014
positive regulation of cellular amino acid metabolic processGO:004576400.013
cellular amide metabolic processGO:004360340.013
response to nutrientGO:000758430.013
regulation of metal ion transportGO:001095940.013
regulation of anatomical structure morphogenesisGO:00226031300.013
positive regulation of map kinase activityGO:004340630.013
alcohol biosynthetic processGO:004616520.013
wound healingGO:0042060900.013
developmental growthGO:00485891660.013
regulation of cellular protein catabolic processGO:190336210.013
spermatid differentiationGO:004851520.013
regulation of circadian rhythmGO:004275240.013
actin filament polymerizationGO:003004120.013
response to abiotic stimulusGO:00096281220.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
negative regulation of intracellular transportGO:003238730.013
nucleic acid transportGO:005065720.013
cytoplasm organizationGO:000702840.013
actin filament based movementGO:003004810.013
activation of mapk activityGO:000018730.013
neuron projection morphogenesisGO:00488121610.013
regulation of stem cell differentiationGO:200073640.013
negative regulation of cytoplasmic transportGO:190365020.013
action potentialGO:0001508190.013
endosomal transportGO:001619720.013
glucose homeostasisGO:004259310.013
positive regulation of dna templated transcription elongationGO:003278610.013
regulation of stem cell proliferationGO:007209120.013
negative regulation of kinase activityGO:003367340.013
segmentationGO:0035282970.013
negative regulation of protein transportGO:005122430.013
regulation of exocytosisGO:001715710.012
g1 s transition of mitotic cell cycleGO:000008210.012
interspecies interaction between organismsGO:004441940.012
peptidyl serine modificationGO:001820920.012
positive regulation of dna metabolic processGO:005105410.012
regulation of response to biotic stimulusGO:000283120.012
positive regulation of stress activated mapk cascadeGO:003287430.012
sensory perception of chemical stimulusGO:000760630.012
taxisGO:00423301090.012
phosphate containing compound metabolic processGO:00067961080.012
alternative mrna splicing via spliceosomeGO:000038010.012
regulation of wound healingGO:006104120.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
response to alkaloidGO:004327920.012
regulation of cellular component organizationGO:0051128860.012
response to uvGO:000941130.012
lipid homeostasisGO:005508830.012
regulation of rho protein signal transductionGO:003502320.012
negative regulation of response to stimulusGO:00485851040.012
cell morphogenesis involved in neuron differentiationGO:00486671630.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
regulation of protein complex disassemblyGO:004324410.012
double strand break repairGO:000630230.012
multi organism cellular processGO:004476420.012
negative regulation of protein kinase activityGO:000646940.012
negative regulation of cellular catabolic processGO:003133030.012
neurotransmitter transportGO:000683620.012
negative regulation of signal transductionGO:0009968940.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
apoptotic processGO:00069151160.012
urogenital system developmentGO:0001655970.012
regulation of localizationGO:00328791040.012
embryo development ending in birth or egg hatchingGO:00097922710.012
eye morphogenesisGO:00485921440.012
hormone transportGO:000991420.012
cellular response to oxygen levelsGO:007145310.012
regulation of autophagyGO:001050630.012
small molecule catabolic processGO:004428230.012
mesenchyme developmentGO:00604851270.011
muscle cell differentiationGO:00426921390.011
cellular component assembly involved in morphogenesisGO:00109271070.011
cell cycle arrestGO:000705010.011
cytoskeleton organizationGO:0007010960.011
organelle assemblyGO:00709251100.011
vacuolar transportGO:000703420.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
circadian sleep wake cycle processGO:002241020.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
circadian sleep wake cycle sleepGO:005080210.011
heart processGO:0003015710.011
response to ketoneGO:190165410.011
neurological system processGO:0050877620.011
startle responseGO:000196440.011
neuronal action potentialGO:0019228180.011
regulation of hormone secretionGO:004688320.011
heart morphogenesisGO:00030071560.011
cellular monovalent inorganic cation homeostasisGO:003000420.011
rna export from nucleusGO:000640510.011
positive regulation of notch signaling pathwayGO:004574730.011
single fertilizationGO:000733830.011
regenerationGO:0031099910.011
purine nucleoside monophosphate catabolic processGO:000912840.011
lateral line system developmentGO:0048925760.011
deathGO:00162651210.011
regulation of striated muscle contractionGO:000694220.011
epithelial tube morphogenesisGO:00605621480.011
ventricular cardiac muscle tissue developmentGO:000322930.011
establishment of rna localizationGO:005123630.011
cell cycle g2 m phase transitionGO:004483940.011
somatic cell dna recombinationGO:001644410.011
negative regulation of metabolic processGO:0009892860.011
g2 m transition of mitotic cell cycleGO:000008640.011
negative regulation of signalingGO:0023057960.011
epithelial cell differentiationGO:00308551160.011
female meiotic divisionGO:000714320.011
signal transduction in absence of ligandGO:003803410.011
cell deathGO:00082191210.011
regulation of cell matrix adhesionGO:000195210.011
positive regulation of canonical wnt signaling pathwayGO:009026340.011
regulation of blood coagulationGO:003019310.011
nucleobase containing compound transportGO:001593120.011
negative regulation of synapse assemblyGO:005196420.011
cell migration involved in gastrulationGO:0042074790.011
programmed cell deathGO:00125011190.011
regulation of protein polymerizationGO:003227120.011
transmission of nerve impulseGO:0019226190.011
regulation of dna replicationGO:000627530.011
small gtpase mediated signal transductionGO:000726480.011
ameboidal type cell migrationGO:00016671430.011
synaptic target recognitionGO:000803910.011
cytoskeleton dependent cytokinesisGO:006164030.011
regulation of epithelial cell proliferationGO:005067830.011
b cell mediated immunityGO:001972430.011
gastrulation with mouth forming secondGO:0001702440.011
golgi vesicle transportGO:004819330.011
stem cell differentiationGO:00488631170.011
fertilizationGO:000956630.011
regulation of blood vessel sizeGO:005088020.011
negative regulation of defense responseGO:003134820.011
regulation of systemic arterial blood pressureGO:000307310.011
positive regulation of multi organism processGO:004390230.011
protein polyubiquitinationGO:000020940.010
neuron neuron synaptic transmissionGO:000727010.010
negative regulation of nitrogen compound metabolic processGO:0051172590.010
negative regulation of dna metabolic processGO:005105340.010
regulation of synaptic plasticityGO:004816710.010
wnt signaling pathwayGO:0016055800.010
phosphorus metabolic processGO:00067931090.010
neurotransmitter secretionGO:000726920.010
kidney developmentGO:0001822920.010
regulation of circadian sleep wake cycle sleepGO:004518710.010
erk1 and erk2 cascadeGO:007037140.010
positive regulation of erk1 and erk2 cascadeGO:007037420.010
negative regulation of cell communicationGO:0010648960.010
female gonad developmentGO:000858540.010
regulation of sequestering of calcium ionGO:005128240.010

eif2b1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.073
nervous system diseaseDOID:86300.029
musculoskeletal system diseaseDOID:1700.019
muscular diseaseDOID:008000000.015
cancerDOID:16200.014
disease of cellular proliferationDOID:1456600.014
disease of metabolismDOID:001466700.013
organ system cancerDOID:005068600.013
eye diseaseDOID:561400.013
eye and adnexa diseaseDOID:149200.013
sensory system diseaseDOID:005015500.013
muscle tissue diseaseDOID:6600.012
myopathyDOID:42300.012
inherited metabolic disorderDOID:65500.011