Danio rerio

0 known processes

pigl

phosphatidylinositol glycan anchor biosynthesis, class L

(Aliases: si:ch211-202a12.6,im:6902701)

pigl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.104
agingGO:000756820.057
positive regulation of transportGO:005105020.050
maintenance of locationGO:005123540.044
proteolysis involved in cellular protein catabolic processGO:005160330.044
meiotic nuclear divisionGO:000712640.041
modification dependent protein catabolic processGO:001994130.040
ubiquitin dependent protein catabolic processGO:000651130.038
cellular protein catabolic processGO:004425740.038
proteasomal protein catabolic processGO:001049820.038
modification dependent macromolecule catabolic processGO:004363230.035
lipid storageGO:001991510.035
multicellular organism growthGO:003526440.034
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.034
positive regulation of catabolic processGO:000989640.031
nuclear transportGO:005116940.030
nucleocytoplasmic transportGO:000691340.030
regulation of cytokine productionGO:000181730.030
positive regulation of cellular catabolic processGO:003133130.030
amine metabolic processGO:000930820.030
establishment of protein localization to organelleGO:007259440.030
regulation of establishment of protein localizationGO:007020140.029
protein importGO:001703830.029
phagocytosisGO:000690930.029
mitochondrion organizationGO:000700540.028
autophagyGO:000691440.028
cellular macromolecule metabolic processGO:00442603910.028
cellular response to external stimulusGO:007149620.028
nitrogen compound metabolic processGO:00068073190.028
regulation of multicellular organism growthGO:004001440.027
cellular amine metabolic processGO:004410620.027
regulation of bindingGO:005109830.027
positive regulation of cell cycleGO:004578730.027
regulation of protein transportGO:005122330.027
single organism nuclear importGO:190259330.027
meiotic cell cycle processGO:190304630.027
regulation of metabolic processGO:00192223590.027
signal transductionGO:00071654550.026
nucleobase containing compound metabolic processGO:00061392740.025
regulation of intracellular protein transportGO:003315730.025
regulation of mrna processingGO:005068430.024
regulation of protein catabolic processGO:004217610.024
regulation of protein complex assemblyGO:004325430.024
nuclear importGO:005117030.024
gtp metabolic processGO:004603940.024
biosynthetic processGO:00090582940.024
cellular nitrogen compound metabolic processGO:00346412900.024
regulation of protein localization to nucleusGO:190018020.024
response to drugGO:004249330.024
guanosine containing compound metabolic processGO:190106840.023
endosomal transportGO:001619720.023
regulation of protein targetingGO:190353320.023
guanosine containing compound catabolic processGO:190106920.023
negative regulation of protein phosphorylationGO:000193340.023
heterocycle metabolic processGO:00464832900.023
positive regulation of cellular component biogenesisGO:004408930.023
gtp catabolic processGO:000618420.023
regulation of macromolecule metabolic processGO:00602553170.023
protein localization to nucleusGO:003450430.022
organic substance biosynthetic processGO:19015762890.022
protein import into nucleusGO:000660630.022
regulation of cellular amine metabolic processGO:003323800.022
regulation of nitrogen compound metabolic processGO:00511712510.022
cellular nitrogen compound biosynthetic processGO:00442712180.022
response to chemicalGO:00422213200.022
peptidyl lysine acetylationGO:001839420.022
regulation of nucleocytoplasmic transportGO:004682220.022
protein acetylationGO:000647320.022
regulation of protein import into nucleusGO:004230620.022
cellular response to extracellular stimulusGO:003166820.022
regulation of cellular amino acid metabolic processGO:000652100.022
protein localization to plasma membraneGO:007265910.022
cellular component disassemblyGO:002241110.022
regulation of cytoplasmic transportGO:190364940.022
regulation of biological qualityGO:00650082630.022
regulation of nucleotide catabolic processGO:003081120.021
cellular aromatic compound metabolic processGO:00067252950.021
cellular response to nutrient levelsGO:003166920.021
regulation of cell shapeGO:000836010.021
response to stressGO:00069502630.021
gene expressionGO:00104672520.021
single organism membrane fusionGO:004480120.021
membrane fusionGO:006102520.021
cellular response to starvationGO:000926710.021
rna metabolic processGO:00160702190.021
single organism metabolic processGO:00447102170.021
rna localizationGO:000640340.021
regulation of primary metabolic processGO:00800903110.021
regulation of cellular metabolic processGO:00313233200.020
cytokinesisGO:000091030.020
regulation of protein ubiquitinationGO:003139630.020
protein acylationGO:004354330.020
regulation of meiotic cell cycleGO:005144510.020
organelle fusionGO:004828430.020
protein targeting to nucleusGO:004474430.020
regulation of cell activationGO:005086510.020
organic cyclic compound metabolic processGO:19013603010.020
internal protein amino acid acetylationGO:000647520.020
multi organism cellular processGO:004476420.019
central nervous system developmentGO:00074173870.019
stem cell maintenanceGO:001982740.019
positive regulation of protein complex assemblyGO:003133420.019
transportGO:00068102200.019
regulation of protein modification by small protein conjugation or removalGO:190332030.019
establishment of localizationGO:00512342440.019
development of primary female sexual characteristicsGO:004654540.019
protein polymerizationGO:005125840.019
meiotic chromosome segregationGO:004513230.019
heterocycle biosynthetic processGO:00181302150.019
positive regulation of cytokine productionGO:000181920.018
regulation of mrna splicing via spliceosomeGO:004802430.018
cellular amino acid metabolic processGO:000652070.018
regulation of purine nucleotide catabolic processGO:003312120.018
regulation of gene expressionGO:00104682650.018
positive regulation of cellular amine metabolic processGO:003324000.018
nucleic acid metabolic processGO:00903042440.018
negative regulation of biological processGO:00485193040.018
oxoacid metabolic processGO:0043436310.018
protein polyubiquitinationGO:000020940.018
regulation of nucleoside metabolic processGO:000911820.018
regulation of alternative mrna splicing via spliceosomeGO:000038110.018
organic acid metabolic processGO:0006082310.018
positive regulation of secretionGO:005104710.018
morphogenesis of an epitheliumGO:00020093330.018
organic cyclic compound biosynthetic processGO:19013622230.018
i kappab kinase nf kappab signalingGO:000724940.018
cellular ketone metabolic processGO:0042180110.018
protein metabolic processGO:00195381830.018
aromatic compound biosynthetic processGO:00194382170.018
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.018
response to uvGO:000941130.018
internal peptidyl lysine acetylationGO:001839320.018
organelle organizationGO:00069962270.018
stem cell proliferationGO:007208940.018
positive regulation of secretion by cellGO:190353210.018
cellular biosynthetic processGO:00442492860.018
cognitionGO:005089010.018
protein complex disassemblyGO:004324110.018
organonitrogen compound metabolic processGO:1901564740.017
regulation of synaptic plasticityGO:004816710.017
protein secretionGO:000930610.017
sensory organ developmentGO:00074233930.017
regulation of cellular ketone metabolic processGO:001056570.017
response to topologically incorrect proteinGO:003596620.017
carboxylic acid metabolic processGO:0019752220.017
macromolecule biosynthetic processGO:00090592270.017
g1 s transition of mitotic cell cycleGO:000008210.017
symbiosis encompassing mutualism through parasitismGO:004440340.017
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.017
negative regulation of kinase activityGO:003367340.017
centrosome organizationGO:005129710.017
membrane invaginationGO:001032410.017
regulation of nucleobase containing compound metabolic processGO:00192192500.017
immune system processGO:00023762410.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
transcription dna templatedGO:00063511810.017
spermatid developmentGO:000728620.017
positive regulation of biological processGO:00485182530.017
regulation of cell communicationGO:00106462320.017
positive regulation of cell activationGO:005086710.017
regulation of i kappab kinase nf kappab signalingGO:004312240.017
single organism localizationGO:19025782250.016
rna biosynthetic processGO:00327741810.016
small molecule catabolic processGO:004428230.016
small molecule metabolic processGO:0044281770.016
generation of neuronsGO:00486993850.016
peptide transportGO:001583310.016
single organism transportGO:00447652060.016
regulation of gtp catabolic processGO:003312420.016
phagocytosis engulfmentGO:000691110.016
regulation of cellular biosynthetic processGO:00313262450.016
cellular response to lipopolysaccharideGO:007122230.016
cellular response to biotic stimulusGO:007121630.016
actin polymerization or depolymerizationGO:000815420.016
cell surface receptor signaling pathwayGO:00071663250.016
cell migrationGO:00164772370.016
extrinsic apoptotic signaling pathwayGO:009719130.016
cellular component movementGO:00069283350.016
nucleobase containing compound biosynthetic processGO:00346542050.016
positive regulation of cell adhesionGO:004578510.016
positive regulation of purine nucleotide catabolic processGO:003312310.016
regulation of response to stimulusGO:00485832690.016
regulation of neural precursor cell proliferationGO:200017730.016
tube morphogenesisGO:00352393490.016
cell motilityGO:00488702440.016
golgi vesicle transportGO:004819330.016
alternative mrna splicing via spliceosomeGO:000038010.016
cellular macromolecule biosynthetic processGO:00346452240.016
regulation of synapse organizationGO:005080730.016
nucleic acid templated transcriptionGO:00976591810.016
cell cycle g1 s phase transitionGO:004484310.016
peptidyl serine modificationGO:001820920.016
regulation of autophagyGO:001050630.015
microtubule organizing center organizationGO:003102310.015
macroautophagyGO:001623610.015
cellular component morphogenesisGO:00329893360.015
regulation of gtpase activityGO:004308720.015
cellular response to radiationGO:007147840.015
translational initiationGO:000641330.015
synaptic vesicle transportGO:004848910.015
negative regulation of protein kinase activityGO:000646940.015
ribonucleoside monophosphate catabolic processGO:000915840.015
female gonad developmentGO:000858540.015
positive regulation of stress activated mapk cascadeGO:003287430.015
mitotic dna integrity checkpointGO:004477440.015
female sex differentiationGO:004666040.015
cellular response to molecule of bacterial originGO:007121930.015
locomotionGO:00400113130.015
head developmentGO:00603223030.015
positive regulation of gtpase activityGO:004354710.015
regulation of rna biosynthetic processGO:20011412130.015
production of molecular mediator of immune responseGO:000244020.015
interspecies interaction between organismsGO:004441940.015
meiosis iGO:000712710.015
cellular component biogenesisGO:00440851780.015
secondary metabolic processGO:001974830.015
nuclear exportGO:005116810.015
regulation of rna metabolic processGO:00512522240.015
system processGO:00030081850.015
response to external stimulusGO:00096052640.015
locomotor rhythmGO:004547530.015
neuron differentiationGO:00301823530.015
double strand break repairGO:000630230.015
compound eye developmentGO:004874920.015
cellular carbohydrate metabolic processGO:004426240.015
peptidyl serine phosphorylationGO:001810510.015
negative regulation of catabolic processGO:000989530.015
exocytosisGO:000688710.014
positive regulation of nucleoside metabolic processGO:004597910.014
positive regulation of nucleotide catabolic processGO:003081310.014
single organism organelle organizationGO:19025891990.014
spermatid differentiationGO:004851520.014
leukocyte proliferationGO:007066110.014
macromolecular complex disassemblyGO:003298410.014
cellular response to topologically incorrect proteinGO:003596720.014
regulation of macromolecule biosynthetic processGO:00105562250.014
regulation of reactive oxygen species metabolic processGO:200037720.014
stem cell divisionGO:001714510.014
cell substrate adhesionGO:003158940.014
positive regulation of dna metabolic processGO:005105410.014
adult behaviorGO:003053420.014
positive regulation of gtp catabolic processGO:003312610.014
atp catabolic processGO:000620040.014
actin filament polymerizationGO:003004120.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
regulation of cellular protein catabolic processGO:190336210.014
cellular response to chemical stimulusGO:00708871570.014
regulation of signalingGO:00230512350.014
cell matrix adhesionGO:000716040.014
lateral inhibitionGO:004633110.014
regulation of organelle assemblyGO:190211540.014
embryo development ending in birth or egg hatchingGO:00097922710.014
negative regulation of cytokine productionGO:000181810.014
viral processGO:001603210.014
regulation of production of molecular mediator of immune responseGO:000270010.014
neuroblast proliferationGO:000740520.014
regulation of stem cell differentiationGO:200073640.014
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.014
tissue remodelingGO:004877140.014
fertilizationGO:000956630.014
regulation of biosynthetic processGO:00098892500.014
rna transportGO:005065820.014
post embryonic organ developmentGO:004856940.014
response to carbohydrateGO:000974330.014
mononuclear cell proliferationGO:003294310.014
cytoplasm organizationGO:000702840.014
single fertilizationGO:000733830.013
eye developmentGO:00016542770.013
regulation of circadian rhythmGO:004275240.013
cellular component assemblyGO:00226071700.013
mitotic dna damage checkpointGO:004477340.013
positive regulation of i kappab kinase nf kappab signalingGO:004312330.013
homeostatic processGO:00425921420.013
brain developmentGO:00074202930.013
cell morphogenesisGO:00009022890.013
nucleobase containing compound transportGO:001593120.013
dna templated transcription elongationGO:000635430.013
negative regulation of protein complex assemblyGO:003133310.013
vacuolar transportGO:000703420.013
negative regulation of nucleocytoplasmic transportGO:004682320.013
cell projection organizationGO:00300302840.013
regulation of reproductive processGO:200024140.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
synaptic growth at neuromuscular junctionGO:005112420.013
cellular protein metabolic processGO:00442671290.013
regulation of developmental processGO:00507932470.013
regulation of signal transductionGO:00099662250.013
regulation of metal ion transportGO:001095940.013
digestive system developmentGO:00551232890.013
negative regulation of cellular catabolic processGO:003133030.013
regulation of multicellular organismal processGO:00512392770.013
positive regulation of map kinase activityGO:004340630.013
cell part morphogenesisGO:00329902460.013
regulation of dna replicationGO:000627530.013
transcription elongation from rna polymerase ii promoterGO:000636830.013
response to hydrogen peroxideGO:004254230.013
regulation of transcription dna templatedGO:00063552130.013
positive regulation of cellular processGO:00485222010.013
positive regulation of cytoskeleton organizationGO:005149530.013
negative regulation of cellular processGO:00485232830.013
response to monosaccharideGO:003428430.013
positive regulation of immune effector processGO:000269930.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
protein stabilizationGO:005082120.013
localization of cellGO:00516742440.012
neuron developmentGO:00486662620.012
embryonic organ morphogenesisGO:00485622740.012
regulation of protein polymerizationGO:003227120.012
cellular amide metabolic processGO:004360340.012
b cell activationGO:004211320.012
digestive tract morphogenesisGO:00485462310.012
regulation of nucleic acid templated transcriptionGO:19035062130.012
hemopoiesisGO:00300971830.012
regulation of protein complex disassemblyGO:004324410.012
protein dephosphorylationGO:000647030.012
negative regulation of mapk cascadeGO:004340940.012
regulation of blood pressureGO:000821710.012
carboxylic acid catabolic processGO:004639530.012
female meiotic divisionGO:000714320.012
nucleoside monophosphate catabolic processGO:000912540.012
regulation of stem cell proliferationGO:007209120.012
positive regulation of canonical wnt signaling pathwayGO:009026340.012
response to organic substanceGO:00100331530.012
developmental programmed cell deathGO:001062340.012
establishment of rna localizationGO:005123630.012
intracellular signal transductionGO:0035556850.012
cellular respirationGO:004533330.012
negative regulation of cytoplasmic transportGO:190365020.012
regulation of transporter activityGO:003240920.012
regulation of response to biotic stimulusGO:000283120.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
embryonic organ developmentGO:00485683810.012
regulation of dna templated transcription elongationGO:003278430.012
response to glucoseGO:000974930.012
somatic stem cell maintenanceGO:003501910.012
chemosensory behaviorGO:000763510.012
macromolecule modificationGO:00434121110.012
antimicrobial humoral responseGO:001973020.012
cellular protein modification processGO:00064641000.012
erk1 and erk2 cascadeGO:007037140.012
response to nutrientGO:000758430.012
centrosome cycleGO:000709810.012
positive regulation of chromosome organizationGO:200125210.012
negative regulation of nuclear divisionGO:005178430.012
lamellipodium assemblyGO:003003210.012
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.012
regulation of synapse assemblyGO:005196330.012
sequestering of calcium ionGO:005120830.012
carbohydrate homeostasisGO:003350010.011
blood vessel developmentGO:00015682460.011
negative regulation of intracellular transportGO:003238730.011
cell projection morphogenesisGO:00488582440.011
mitochondrial transportGO:000683920.011
xenobiotic metabolic processGO:000680540.011
cytoskeleton dependent cytokinesisGO:006164030.011
digestive tract developmentGO:00485652650.011
cellular response to light stimulusGO:007148240.011
intracellular mrna localizationGO:000829810.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
positive regulation of jnk cascadeGO:004633030.011
synaptic vesicle localizationGO:009747910.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
hormone secretionGO:004687920.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
transcription from rna polymerase ii promoterGO:0006366800.011
mitotic g2 dna damage checkpointGO:000709530.011
establishment of synaptic vesicle localizationGO:009748010.011
heart developmentGO:00075073130.011
hormone transportGO:000991420.011
regulation of inflammatory responseGO:005072720.011
response to abiotic stimulusGO:00096281220.011
startle responseGO:000196440.011
regulation of exocytosisGO:001715710.011
response to alkaloidGO:004327920.011
phosphate containing compound metabolic processGO:00067961080.011
lymphocyte proliferationGO:004665110.011
purine nucleoside monophosphate catabolic processGO:000912840.011
regulation of erk1 and erk2 cascadeGO:007037240.011
gastrulationGO:00073692080.011
sequestering of metal ionGO:005123830.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
regulation of carbohydrate metabolic processGO:000610940.011
specification of symmetryGO:00097992040.011
negative regulation of map kinase activityGO:004340720.011
rna export from nucleusGO:000640510.011
g2 dna damage checkpointGO:003157230.011
nucleic acid transportGO:005065720.011
positive regulation of translationGO:004572710.011
response to unfolded proteinGO:000698620.011
primary neural tube formationGO:001402010.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
regulation of jak stat cascadeGO:004642530.011
apoptotic processGO:00069151160.011
organic acid catabolic processGO:001605430.011
cell deathGO:00082191210.011
mitotic cell cycle embryonicGO:004544820.011
cell substrate junction assemblyGO:000704420.011
regulation of jun kinase activityGO:004350630.011
growthGO:00400071740.011
multi organism processGO:00517041340.011
er to golgi vesicle mediated transportGO:000688810.010
regulation of rho protein signal transductionGO:003502320.010
cellular localizationGO:0051641970.010
hematopoietic or lymphoid organ developmentGO:00485341910.010
protein modification processGO:00362111000.010
deathGO:00162651210.010
negative regulation of multi organism processGO:004390130.010
spindle assemblyGO:005122520.010
cellular response to organic substanceGO:00713101050.010
regionalizationGO:00030022740.010
muscle structure developmentGO:00610611960.010
immune system developmentGO:00025201910.010
regulation of hormone secretionGO:004688320.010
regulation of chromosome segregationGO:005198310.010
negative regulation of synapse assemblyGO:005196420.010
positive regulation of multi organism processGO:004390230.010
somatic muscle developmentGO:000752540.010
peptidyl threonine phosphorylationGO:001810710.010
negative regulation of protein localization to nucleusGO:190018120.010
chordate embryonic developmentGO:00430092710.010
determination of bilateral symmetryGO:00098552040.010
positive regulation of chromatin modificationGO:190331010.010
negative regulation of defense responseGO:003134820.010
cytosolic calcium ion transportGO:006040130.010
tube closureGO:006060610.010
mrna transportGO:005102820.010
positive regulation of cell divisionGO:005178120.010
regulation of organ growthGO:004662030.010
neurotransmitter transportGO:000683620.010
regulation of filopodium assemblyGO:005148920.010

pigl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.021
musculoskeletal system diseaseDOID:1700.015
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
organ system cancerDOID:005068600.013
disease of metabolismDOID:001466700.012
sensory system diseaseDOID:005015500.011
eye and adnexa diseaseDOID:149200.011
myopathyDOID:42300.010
muscular diseaseDOID:008000000.010
heart diseaseDOID:11400.010
cardiomyopathyDOID:005070000.010
intrinsic cardiomyopathyDOID:006003600.010
muscle tissue diseaseDOID:6600.010
cardiovascular system diseaseDOID:128700.010
inherited metabolic disorderDOID:65500.010