Danio rerio

36 known processes

slc4a1a

solute carrier family 4, anion exchanger, member 1a

(Aliases: ae1,MGC152771,zgc:152771,band3,zgc:111889,si:dz180g5.1,slc4a1)

slc4a1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
primitive erythrocyte differentiationGO:006031950.999
erythrocyte maturationGO:004324980.997
erythrocyte differentiationGO:0030218540.984
erythrocyte homeostasisGO:0034101550.982
homeostasis of number of cellsGO:0048872620.931
myeloid cell homeostasisGO:0002262560.838
embryonic organ developmentGO:00485683810.803
immune system developmentGO:00025201910.784
immune system processGO:00023762410.775
cellular transition metal ion homeostasisGO:004691630.774
erythrocyte developmentGO:0048821240.762
hemopoiesisGO:00300971830.758
myeloid cell differentiationGO:0030099860.741
heme metabolic processGO:004216890.666
metal ion transportGO:0030001580.585
Zebrafish
maintenance of locationGO:005123540.576
iron ion homeostasisGO:005507240.576
cofactor biosynthetic processGO:0051188100.546
embryonic hemopoiesisGO:0035162530.544
homeostatic processGO:00425921420.489
regulation of biological qualityGO:00650082630.488
regulation of protein bindingGO:004339330.487
hematopoietic or lymphoid organ developmentGO:00485341910.417
tetrapyrrole biosynthetic processGO:003301480.409
primitive hemopoiesisGO:0060215270.378
cellular iron ion homeostasisGO:000687930.370
cellular amide metabolic processGO:004360340.360
larval developmentGO:000216420.316
iron ion transportGO:000682640.299
gas transportGO:001566930.248
positive regulation of myeloid cell differentiationGO:004563920.246
regulation of bindingGO:005109830.222
lipid storageGO:001991510.218
swimming behaviorGO:003626980.211
heart developmentGO:00075073130.209
regulation of anatomical structure morphogenesisGO:00226031300.207
regulation of cellular ph reductionGO:003284710.205
transition metal ion homeostasisGO:005507650.191
regulation of multicellular organismal developmentGO:20000262230.172
porphyrin containing compound metabolic processGO:0006778100.172
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.170
hypotonic salinity responseGO:004253950.168
cellular response to external stimulusGO:007149620.164
agingGO:000756820.164
regulation of erythrocyte differentiationGO:004564620.161
dipeptide transportGO:004293810.158
removal of superoxide radicalsGO:001943020.156
regulation of intracellular phGO:005145310.154
cell projection morphogenesisGO:00488582440.154
axonal fasciculationGO:0007413110.144
ectodermal cell fate specificationGO:000171520.143
nucleic acid metabolic processGO:00903042440.138
transition metal ion transportGO:000004160.137
positive regulation of neuron migrationGO:200122420.134
regulation of i kappab kinase nf kappab signalingGO:004312240.130
regulation of ectoderm developmentGO:200038320.129
sodium ion importGO:009736930.128
negative regulation of developmental processGO:0051093650.126
response to stressGO:00069502630.126
muscle cell differentiationGO:00426921390.122
somatic muscle developmentGO:000752540.117
regulation of translational initiationGO:000644610.113
heart morphogenesisGO:00030071560.110
neuron projection morphogenesisGO:00488121610.110
generation of neuronsGO:00486993850.108
response to salt stressGO:0009651100.108
hatching gland developmentGO:004878530.103
signal transductionGO:00071654550.102
regulation of multicellular organismal processGO:00512392770.100
actin cytoskeleton organizationGO:0030036630.098
hatchingGO:003518840.097
cell morphogenesis involved in differentiationGO:00009041950.094
regulation of ectodermal cell fate specificationGO:004266520.094
cellular biosynthetic processGO:00442492860.094
macromolecular complex assemblyGO:0065003350.094
localization of cellGO:00516742440.093
positive regulation of biological processGO:00485182530.091
cellular component movementGO:00069283350.090
positive regulation of i kappab kinase nf kappab signalingGO:004312330.088
hydrogen peroxide metabolic processGO:004274320.087
neuron developmentGO:00486662620.086
muscle structure developmentGO:00610611960.086
actin filament polymerizationGO:003004120.083
organic substance biosynthetic processGO:19015762890.082
liver developmentGO:0001889960.082
cellular response to chemical stimulusGO:00708871570.082
neuron differentiationGO:00301823530.082
single organism localizationGO:19025782250.081
carbon dioxide transportGO:001567030.081
rna biosynthetic processGO:00327741810.080
regulation of protein complex assemblyGO:004325430.079
negative regulation of biological processGO:00485193040.079
hemoglobin metabolic processGO:0020027120.078
organonitrogen compound biosynthetic processGO:1901566470.078
hemoglobin biosynthetic processGO:004254180.076
cell surface receptor signaling pathwayGO:00071663250.075
multicellular organism growthGO:003526440.073
regulation of macromolecule metabolic processGO:00602553170.073
cellular homeostasisGO:0019725260.073
endosomal transportGO:001619720.069
heme biosynthetic processGO:000678380.069
cellular response to superoxideGO:007145120.068
pancreas developmentGO:0031016840.067
cofactor metabolic processGO:0051186150.067
cellular cation homeostasisGO:0030003170.066
tube morphogenesisGO:00352393490.065
establishment of blood brain barrierGO:006085620.064
porphyrin containing compound biosynthetic processGO:000677980.063
protein complex subunit organizationGO:0071822460.062
rna metabolic processGO:00160702190.062
neuron neuron synaptic transmissionGO:000727010.062
optic nerve morphogenesisGO:002163160.060
sodium ion transportGO:0006814240.057
Zebrafish
biosynthetic processGO:00090582940.056
oligopeptide transportGO:000685710.056
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.055
multicellular organismal metabolic processGO:004423620.055
striated muscle cell differentiationGO:00511461290.055
macromolecular complex subunit organizationGO:0043933740.054
positive regulation of wound healingGO:009030310.054
lamellipodium organizationGO:009758110.052
regulation of protein depolymerizationGO:190187910.052
endocrine hormone secretionGO:006098620.052
modification dependent macromolecule catabolic processGO:004363230.051
regulation of embryonic developmentGO:0045995470.051
cellular macromolecule metabolic processGO:00442603910.051
protein metabolic processGO:00195381830.051
cellular component morphogenesisGO:00329893360.050
regulation of transmembrane transportGO:0034762180.050
positive regulation of response to stimulusGO:0048584800.050
cell recognitionGO:0008037190.049
organic cyclic compound metabolic processGO:19013603010.048
cell part morphogenesisGO:00329902460.048
cytokinesisGO:000091030.047
cellular response to extracellular stimulusGO:003166820.047
regulation of molecular functionGO:0065009700.047
cellular nitrogen compound metabolic processGO:00346412900.047
regulation of cytokine productionGO:000181730.046
muscle cell developmentGO:00550011150.046
regulation of homeostatic processGO:003284490.046
blood vessel developmentGO:00015682460.046
axon developmentGO:00615641660.046
regulation of cellular component organizationGO:0051128860.045
cell projection organizationGO:00300302840.045
regulation of metabolic processGO:00192223590.044
regulation of developmental processGO:00507932470.044
positive regulation of catabolic processGO:000989640.044
cell morphogenesisGO:00009022890.043
heart processGO:0003015710.043
nucleobase containing compound metabolic processGO:00061392740.042
axonogenesisGO:00074091520.042
positive regulation of transportGO:005105020.041
actin filament based processGO:0030029640.041
positive regulation of nitrogen compound metabolic processGO:0051173690.041
regulation of establishment of protein localizationGO:007020140.041
cellular response to lipopolysaccharideGO:007122230.041
regulation of locomotionGO:0040012550.040
vasculature developmentGO:00019442780.040
organelle assemblyGO:00709251100.039
taxisGO:00423301090.039
regulation of extrinsic apoptotic signaling pathwayGO:200123630.038
ion transmembrane transportGO:0034220910.038
Zebrafish Mouse
response to oxygen radicalGO:000030520.038
lipid digestionGO:004424130.038
tetrapyrrole metabolic processGO:0033013100.038
anatomical structure homeostasisGO:0060249360.038
cranial nerve formationGO:0021603130.037
positive regulation of map kinase activityGO:004340630.037
phagocytosisGO:000690930.037
inorganic ion transmembrane transportGO:0098660570.037
Zebrafish Mouse
neuron projection guidanceGO:0097485860.037
ion homeostasisGO:0050801410.036
glial cell differentiationGO:0010001420.036
heterocycle metabolic processGO:00464832900.036
single organism organelle organizationGO:19025891990.035
type i interferon productionGO:003260620.035
cellular protein metabolic processGO:00442671290.035
regulation of transcription dna templatedGO:00063552130.035
peptide transportGO:001583310.034
oxoacid metabolic processGO:0043436310.034
neuron projection developmentGO:00311751800.034
neuron recognitionGO:0008038180.034
organonitrogen compound metabolic processGO:1901564740.034
nitrogen compound metabolic processGO:00068073190.033
fatty acid elongationGO:003049710.033
embryo development ending in birth or egg hatchingGO:00097922710.033
cell morphogenesis involved in neuron differentiationGO:00486671630.032
ph reductionGO:004585110.032
macromolecular complex disassemblyGO:003298410.032
septum transversum developmentGO:000334340.032
cellular modified amino acid metabolic processGO:000657530.032
gastrulationGO:00073692080.032
negative regulation of protein complex assemblyGO:003133310.031
gliogenesisGO:0042063450.031
nucleic acid templated transcriptionGO:00976591810.031
cellular component assemblyGO:00226071700.031
cell motilityGO:00488702440.031
cellular ion homeostasisGO:0006873170.031
regulation of protein transportGO:005122330.031
regulation of protein polymerizationGO:003227120.030
metal ion homeostasisGO:0055065260.030
ectodermal cell differentiationGO:001066820.030
centrosome duplicationGO:005129810.030
cation homeostasisGO:0055080330.030
system processGO:00030081850.030
regulation of synapse assemblyGO:005196330.030
superoxide metabolic processGO:000680120.030
protein complex assemblyGO:0006461300.030
macromolecule biosynthetic processGO:00090592270.029
peptidyl serine modificationGO:001820920.029
regulation of cell differentiationGO:00455951420.029
response to woundingGO:00096111160.028
hepaticobiliary system developmentGO:0061008980.028
platelet formationGO:003022010.028
centrosome cycleGO:000709810.028
regulation of localizationGO:00328791040.028
striated muscle cell developmentGO:00550021080.027
regulation of hydrogen peroxide metabolic processGO:001031010.027
regulation of cellular macromolecule biosynthetic processGO:20001122220.026
response to glucocorticoidGO:005138410.026
i kappab kinase nf kappab signalingGO:000724940.026
heart loopingGO:0001947940.026
proepicardium developmentGO:000334240.026
protein heterooligomerizationGO:005129110.025
regulation of biomineral tissue developmentGO:007016720.025
myofibril assemblyGO:0030239480.025
cellular nitrogen compound biosynthetic processGO:00442712180.025
wound healingGO:0042060900.025
aromatic compound biosynthetic processGO:00194382170.025
cell migrationGO:00164772370.025
protein complex biogenesisGO:0070271300.025
cranial nerve developmentGO:0021545420.025
regulation of rna metabolic processGO:00512522240.024
epithelial cell developmentGO:0002064420.024
regulation of blood vessel sizeGO:005088020.024
actomyosin structure organizationGO:0031032530.024
tissue homeostasisGO:0001894250.024
heterocycle biosynthetic processGO:00181302150.024
hypotonic responseGO:000697150.024
regulation of tube sizeGO:003515020.024
small molecule metabolic processGO:0044281770.023
cellular response to molecule of bacterial originGO:007121930.023
organism emergence from protective structureGO:007168440.023
centrosome organizationGO:005129710.023
mesoderm formationGO:0001707430.023
response to chemicalGO:00422213200.023
Zebrafish
negative regulation of embryonic developmentGO:0045992110.023
transmembrane transportGO:00550851200.022
Zebrafish Mouse
transcription dna templatedGO:00063511810.022
regulation of apoptotic processGO:0042981980.022
cellular component biogenesisGO:00440851780.022
innate immune responseGO:0045087130.022
regulation of multicellular organism growthGO:004001440.022
ameboidal type cell migrationGO:00016671430.022
immune responseGO:0006955280.022
regulation of cell shapeGO:000836010.022
extrinsic apoptotic signaling pathwayGO:009719130.021
rna localizationGO:000640340.021
cellular component disassemblyGO:002241110.021
defense responseGO:0006952470.021
cytoplasm organizationGO:000702840.021
brain developmentGO:00074202930.021
gene expressionGO:00104672520.021
digestive tract morphogenesisGO:00485462310.021
central nervous system developmentGO:00074173870.021
protein complex disassemblyGO:004324110.021
regulation of nitrogen compound metabolic processGO:00511712510.021
positive regulation of multicellular organismal processGO:0051240520.021
regulation of cell motilityGO:2000145460.021
regulation of metal ion transportGO:001095940.020
response to bacteriumGO:0009617580.020
megakaryocyte developmentGO:003585510.020
mitochondrion organizationGO:000700540.020
dna catabolic processGO:000630810.020
ammonia homeostasisGO:009727230.020
positive regulation of cellular catabolic processGO:003133130.019
long chain fatty acid biosynthetic processGO:004275910.019
protein targeting to membraneGO:000661210.019
negative regulation of cellular processGO:00485232830.019
regulation of cellular biosynthetic processGO:00313262450.019
cellular response to oxygen radicalGO:007145020.019
regulation of cellular phGO:003064110.019
homeostasis of number of cells within a tissueGO:004887340.019
chemical homeostasisGO:0048878490.019
positive regulation of developmental processGO:0051094500.018
regulation of signalingGO:00230512350.018
regulation of signal transductionGO:00099662250.018
transportGO:00068102200.018
protein polymerizationGO:005125840.018
circulatory system processGO:0003013870.018
response to superoxideGO:000030320.018
cellular response to xenobiotic stimulusGO:0071466350.018
positive regulation of cytosolic calcium ion concentrationGO:000720440.018
epithelial cell differentiationGO:00308551160.018
negative regulation of protein phosphorylationGO:000193340.018
regulation of synapse organizationGO:005080730.018
axon guidanceGO:0007411860.017
positive regulation of rna biosynthetic processGO:1902680570.017
locomotory behaviorGO:0007626340.017
positive regulation of cell activationGO:005086710.017
olfactory bulb developmentGO:002177240.017
fin developmentGO:0033333770.017
calcium mediated signalingGO:001972220.016
nitric oxide mediated signal transductionGO:000726320.016
transcription from rna polymerase ii promoterGO:0006366800.016
negative regulation of gene expressionGO:0010629650.016
macromolecule catabolic processGO:0009057150.016
single organism transportGO:00447652060.016
regulation of protein complex disassemblyGO:004324410.016
regulation of cell communicationGO:00106462320.016
one carbon compound transportGO:0019755140.016
leukocyte proliferationGO:007066110.016
cellular protein complex disassemblyGO:004362410.015
regulation of reactive oxygen species metabolic processGO:200037720.015
negative regulation of mesodermal cell fate specificationGO:004266230.015
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.015
nuclear importGO:005117030.015
response to nutrient levelsGO:0031667100.015
protein importGO:001703830.015
cellular response to reactive oxygen speciesGO:003461420.015
enzyme linked receptor protein signaling pathwayGO:00071671060.015
fatty acid elongation unsaturated fatty acidGO:001936810.015
very long chain fatty acid biosynthetic processGO:004276140.015
reactive oxygen species metabolic processGO:007259360.015
positive regulation of cell communicationGO:0010647560.015
platelet morphogenesisGO:003634410.014
cellular response to nutrient levelsGO:003166920.014
nitric oxide metabolic processGO:004620920.014
cell adhesionGO:0007155400.014
cellular metal ion homeostasisGO:0006875160.014
response to inorganic substanceGO:0010035380.014
endocrine processGO:005088620.014
axonal defasciculationGO:000741420.014
response to amineGO:001407510.014
cellular response to biotic stimulusGO:007121630.014
programmed cell deathGO:00125011190.014
lymphocyte activationGO:0046649100.014
collagen metabolic processGO:003296320.014
mesodermal cell differentiationGO:0048333210.014
regulation of phGO:000688530.014
lymphocyte proliferationGO:004665110.014
carboxylic acid metabolic processGO:0019752220.014
osteoclast differentiationGO:003031610.014
single organism metabolic processGO:00447102170.014
response to amphetamineGO:000197510.014
regulation of carbohydrate metabolic processGO:000610940.014
positive regulation of cell adhesionGO:004578510.014
multicellular organismal macromolecule metabolic processGO:004425920.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
synaptic growth at neuromuscular junctionGO:005112420.014
cytoskeleton dependent cytokinesisGO:006164030.013
glial cell developmentGO:0021782200.013
regulation of gene expressionGO:00104682650.013
multi organism processGO:00517041340.013
divalent inorganic cation homeostasisGO:0072507220.013
positive regulation of cellular processGO:00485222010.013
nitric oxide biosynthetic processGO:000680920.013
nerve developmentGO:0021675450.013
regulation of cell migrationGO:0030334400.013
positive regulation of immune effector processGO:000269930.013
defense response to fungusGO:005083220.013
monovalent inorganic cation homeostasisGO:005506790.013
regulation of cytoplasmic transportGO:190364940.013
peptidyl serine phosphorylationGO:001810510.013
renal filtrationGO:0097205100.013
positive regulation of molecular functionGO:0044093330.013
hematopoietic stem cell migrationGO:003570140.013
nuclear transportGO:005116940.013
regulation of interferon beta productionGO:003264810.013
myeloid cell developmentGO:0061515320.013
organic acid metabolic processGO:0006082310.013
hormone transportGO:000991420.013
embryonic cranial skeleton morphogenesisGO:0048701900.012
regulation of bone mineralizationGO:003050020.012
regulation of cell activationGO:005086510.012
regulation of circadian sleep wake cycleGO:004274910.012
positive regulation of myeloid leukocyte differentiationGO:000276310.012
signal transduction in absence of ligandGO:003803410.012
endodermal cell fate determinationGO:000749320.012
negative regulation of myeloid leukocyte differentiationGO:000276210.012
response to copper ionGO:0046688130.012
endomembrane system organizationGO:0010256130.012
ectoderm formationGO:000170520.012
catecholamine metabolic processGO:000658420.012
response to axon injuryGO:0048678140.012
cellular amine metabolic processGO:004410620.012
cellular amino acid metabolic processGO:000652070.012
b cell activationGO:004211320.012
leukocyte homeostasisGO:000177620.012
regulation of autophagyGO:001050630.012
behaviorGO:0007610740.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
regulation of circadian rhythmGO:004275240.012
cellular monovalent inorganic cation homeostasisGO:003000420.012
transcription elongation from rna polymerase ii promoterGO:000636830.011
regulation of cellular component movementGO:0051270550.011
b cell differentiationGO:003018310.011
response to hydrogen peroxideGO:004254230.011
nucleobase containing compound biosynthetic processGO:00346542050.011
ammonium transmembrane transportGO:007248820.011
protein localization to nucleusGO:003450430.011
sensory perception of painGO:001923310.011
cellular carbohydrate metabolic processGO:004426240.011
positive regulation of jak stat cascadeGO:004642720.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
regulation of protein targetingGO:190353320.011
microtubule cytoskeleton organization involved in mitosisGO:190285010.011
ubiquitin dependent protein catabolic processGO:000651130.011
negative regulation of signal transduction in absence of ligandGO:190109910.011
iron ion transmembrane transportGO:003475530.011
regulation of neuronal synaptic plasticityGO:004816810.011
reactive oxygen species biosynthetic processGO:190340910.011
photoreceptor cell fate commitmentGO:004655210.011
response to carbohydrateGO:000974330.011
modification of morphology or physiology of other organismGO:003582140.011
defense response to other organismGO:0098542330.011
regulation of cell deathGO:00109411030.011
lateral ventricle developmentGO:002167010.011
dendrite guidanceGO:007098300.011
response to external stimulusGO:00096052640.011
appendage developmentGO:0048736800.011
regulation of transporter activityGO:003240920.011
positive regulation of secretionGO:005104710.010
cellular response to starvationGO:000926710.010
regulation of cellular amine metabolic processGO:003323800.010
interferon beta productionGO:003260810.010
negative regulation of intracellular transportGO:003238730.010
negative regulation of cell differentiationGO:0045596460.010
chemotaxisGO:00069351040.010
cellular chemical homeostasisGO:0055082170.010
peptidyl tyrosine dephosphorylationGO:003533510.010
symbiosis encompassing mutualism through parasitismGO:004440340.010
inorganic cation transmembrane transportGO:0098662500.010
Zebrafish
glomerular filtrationGO:000309460.010
cerebellar cortex formationGO:002169750.010
actin filament organizationGO:0007015150.010
microtubule organizing center organizationGO:003102310.010

slc4a1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.220
disease of anatomical entityDOID:700.220
hematopoietic system diseaseDOID:7400.220
cancerDOID:16200.043
disease of cellular proliferationDOID:1456600.043
organ system cancerDOID:005068600.043
endocrine gland cancerDOID:17000.036
gastrointestinal system cancerDOID:311900.023
colon cancerDOID:21900.023
colorectal cancerDOID:925600.023
intestinal cancerDOID:1015500.023
large intestine cancerDOID:567200.023
colon carcinomaDOID:152000.023