Danio rerio

0 known processes

cul1a

cullin 1a

(Aliases: zgc:77500,wu:fc13a10,Cul1,zgc:55747)

cul1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.354
Worm
regulation of metabolic processGO:00192223590.322
larval developmentGO:000216420.213
Worm
establishment of localizationGO:00512342440.208
Worm
negative regulation of biological processGO:00485193040.159
Worm Fly
er to golgi vesicle mediated transportGO:000688810.146
regulation of signalingGO:00230512350.139
Fly
cellular component movementGO:00069283350.134
Worm
positive regulation of cellular catabolic processGO:003133130.133
response to stressGO:00069502630.132
Worm Fly
positive regulation of catabolic processGO:000989640.114
positive regulation of cell cycleGO:004578730.101
heterocycle metabolic processGO:00464832900.100
macromolecular complex subunit organizationGO:0043933740.097
cytokinesisGO:000091030.093
cellular nitrogen compound metabolic processGO:00346412900.091
nitrogen compound metabolic processGO:00068073190.089
regulation of cell cycleGO:0051726520.086
Worm Fly
organelle organizationGO:00069962270.086
Worm
cellular component disassemblyGO:002241110.085
cellular component assemblyGO:00226071700.084
negative regulation of metabolic processGO:0009892860.083
regulation of primary metabolic processGO:00800903110.077
mitotic dna integrity checkpointGO:004477440.076
Fly
regulation of gene expressionGO:00104682650.075
regulation of biological qualityGO:00650082630.075
Worm
gene expressionGO:00104672520.073
response to chemicalGO:00422213200.071
Fly
response to drugGO:004249330.070
regulation of signal transductionGO:00099662250.070
Fly
cellular localizationGO:0051641970.067
nuclear transportGO:005116940.066
transportGO:00068102200.066
Worm
nuclear importGO:005117030.065
protein importGO:001703830.064
regulation of protein ubiquitinationGO:003139630.063
maintenance of locationGO:005123540.063
regulation of establishment of protein localizationGO:007020140.063
nuclear migrationGO:000709730.061
protein targeting to nucleusGO:004474430.059
regulation of protein catabolic processGO:004217610.058
positive regulation of cellular processGO:00485222010.056
Worm
cellular component biogenesisGO:00440851780.056
rna localizationGO:000640340.055
symbiosis encompassing mutualism through parasitismGO:004440340.054
locomotor rhythmGO:004547530.054
multicellular organismal macromolecule metabolic processGO:004425920.053
regulation of protein modification by small protein conjugation or removalGO:190332030.053
negative regulation of macromolecule metabolic processGO:0010605760.052
localization of cellGO:00516742440.051
Worm
ubiquitin dependent protein catabolic processGO:000651130.051
Human Mouse
single organism transportGO:00447652060.049
proteolysis involved in cellular protein catabolic processGO:005160330.049
Human Mouse
regulation of cell divisionGO:0051302120.049
negative regulation of cellular processGO:00485232830.048
Worm Fly
regenerationGO:0031099910.048
digestive system developmentGO:00551232890.047
regulation of nitrogen compound metabolic processGO:00511712510.047
nucleobase containing compound metabolic processGO:00061392740.047
regulation of protein complex assemblyGO:004325430.046
regulation of cellular metabolic processGO:00313233200.046
aromatic compound biosynthetic processGO:00194382170.046
regulation of meiotic cell cycleGO:005144510.046
cellular macromolecule metabolic processGO:00442603910.046
Human Mouse
signal transductionGO:00071654550.046
Fly
establishment of protein localization to organelleGO:007259440.045
multi organism processGO:00517041340.045
Worm
cytoskeleton organizationGO:0007010960.045
single organism localizationGO:19025782250.044
cell motilityGO:00488702440.043
Worm
protein complex disassemblyGO:004324110.043
protein modification by small protein removalGO:007064610.042
rna metabolic processGO:00160702190.042
multi organism reproductive processGO:0044703360.042
positive regulation of transportGO:005105020.042
meiotic nuclear divisionGO:000712640.041
modification dependent macromolecule catabolic processGO:004363230.041
Human Mouse
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.040
peptidyl serine phosphorylationGO:001810510.040
regulation of macromolecule metabolic processGO:00602553170.040
regulation of nucleocytoplasmic transportGO:004682220.040
regulation of intracellular protein transportGO:003315730.040
protein complex subunit organizationGO:0071822460.040
regulation of protein transportGO:005122330.040
regulation of cell shapeGO:000836010.040
locomotionGO:00400113130.039
Worm
positive regulation of biological processGO:00485182530.039
Worm
negative regulation of rna metabolic processGO:0051253480.039
dna templated transcription elongationGO:000635430.039
digestive tract developmentGO:00485652650.039
protein localization to nucleusGO:003450430.038
rna biosynthetic processGO:00327741810.038
dorsal ventral pattern formationGO:00099531250.037
single organism reproductive processGO:0044702400.036
Worm
mitotic metaphase plate congressionGO:000708010.036
single organism nuclear importGO:190259330.036
g2 dna damage checkpointGO:003157230.035
Fly
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.035
mrna metabolic processGO:0016071200.035
cellular macromolecule localizationGO:0070727210.034
regulation of cell communicationGO:00106462320.034
Fly
cell deathGO:00082191210.034
Mouse Worm Fly
positive regulation of cell divisionGO:005178120.033
regulation of response to stimulusGO:00485832690.033
Fly
stem cell divisionGO:001714510.033
negative regulation of neuron projection regenerationGO:007057140.033
negative regulation of cellular metabolic processGO:0031324770.033
single organism metabolic processGO:00447102170.033
nucleobase containing compound biosynthetic processGO:00346542050.033
heterocycle biosynthetic processGO:00181302150.033
protein import into nucleusGO:000660630.032
nucleic acid metabolic processGO:00903042440.032
extrinsic apoptotic signaling pathwayGO:009719130.032
organic substance transportGO:0071702580.032
negative regulation of signal transductionGO:0009968940.032
Fly
intracellular signal transductionGO:0035556850.031
Fly
regulation of cellular protein catabolic processGO:190336210.031
positive regulation of chromatin modificationGO:190331010.030
macromolecular complex disassemblyGO:003298410.030
regulation of extrinsic apoptotic signaling pathwayGO:200123630.030
cell surface receptor signaling pathwayGO:00071663250.030
Fly
multicellular organism growthGO:003526440.030
regulation of cellular ketone metabolic processGO:001056570.030
cellular response to external stimulusGO:007149620.030
regulation of synapse organizationGO:005080730.029
embryo development ending in birth or egg hatchingGO:00097922710.029
Worm
organic cyclic compound metabolic processGO:19013603010.029
protein metabolic processGO:00195381830.028
Human Mouse Fly
mitotic g2 m transition checkpointGO:004481830.028
Fly
spliceosomal complex assemblyGO:000024510.028
viral processGO:001603210.028
cell migrationGO:00164772370.028
Worm
nucleocytoplasmic transportGO:000691340.027
single organism organelle organizationGO:19025891990.027
Worm
sexual reproductionGO:0019953360.027
cellular protein metabolic processGO:00442671290.027
Human Mouse
regulation of nucleic acid templated transcriptionGO:19035062130.026
organic cyclic compound biosynthetic processGO:19013622230.026
cellular protein localizationGO:0034613200.026
cell cycleGO:0007049930.026
Worm Fly
gastrulationGO:00073692080.026
synaptic growth at neuromuscular junctionGO:005112420.025
multicellular organismal metabolic processGO:004423620.025
programmed cell deathGO:00125011190.025
Mouse Worm Fly
response to external stimulusGO:00096052640.024
Worm
regulation of rna metabolic processGO:00512522240.024
regulation of cellular component organizationGO:0051128860.024
cellular response to nutrient levelsGO:003166920.024
internal protein amino acid acetylationGO:000647520.024
regulation of cytoplasmic transportGO:190364940.024
meiotic cell cycle processGO:190304630.023
response to organic substanceGO:00100331530.023
Fly
protein localizationGO:0008104400.023
stem cell maintenanceGO:001982740.023
cellular component morphogenesisGO:00329893360.023
protein complex biogenesisGO:0070271300.023
tube morphogenesisGO:00352393490.023
regulation of synaptic plasticityGO:004816710.023
centrosome cycleGO:000709810.023
negative regulation of cytoplasmic transportGO:190365020.022
lipid storageGO:001991510.022
negative regulation of signalingGO:0023057960.022
Fly
spliceosomal snrnp assemblyGO:000038720.022
macromolecular complex assemblyGO:0065003350.022
heart developmentGO:00075073130.021
macromolecule modificationGO:00434121110.021
Human Mouse
protein modification by small protein conjugation or removalGO:0070647140.021
Human Mouse
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.021
Human Mouse
stem cell proliferationGO:007208940.021
cellular response to extracellular stimulusGO:003166820.021
cellular response to starvationGO:000926710.021
germ cell developmentGO:0007281220.021
ribonucleoprotein complex assemblyGO:002261850.021
regulation of protein localization to nucleusGO:190018020.021
neurotransmitter transportGO:000683620.021
protein modification processGO:00362111000.021
Human Mouse
organonitrogen compound metabolic processGO:1901564740.021
multicellular organism reproductionGO:0032504350.020
regulation of metal ion transportGO:001095940.020
interspecies interaction between organismsGO:004441940.020
phosphate containing compound metabolic processGO:00067961080.020
regulation of cellular protein metabolic processGO:0032268520.020
cellular protein modification processGO:00064641000.020
Human Mouse
negative regulation of nucleobase containing compound metabolic processGO:0045934590.020
regulation of intracellular signal transductionGO:1902531570.020
Fly
cellular biosynthetic processGO:00442492860.020
central nervous system developmentGO:00074173870.020
organic substance catabolic processGO:1901575280.020
Human Mouse Fly
small molecule metabolic processGO:0044281770.019
cation transportGO:0006812810.019
macroautophagyGO:001623610.019
regulation of circadian rhythmGO:004275240.019
deathGO:00162651210.019
Mouse Worm Fly
system processGO:00030081850.019
regulation of cell developmentGO:00602841000.019
positive regulation of apoptotic signaling pathwayGO:200123510.019
regulation of protein targetingGO:190353320.019
regulation of chromosome segregationGO:005198310.019
cell morphogenesisGO:00009022890.019
ribonucleoside monophosphate catabolic processGO:000915840.019
negative regulation of gene expressionGO:0010629650.019
transmembrane transportGO:00550851200.019
positive regulation of stress activated mapk cascadeGO:003287430.019
cellular aromatic compound metabolic processGO:00067252950.018
fertilizationGO:000956630.018
positive regulation of cellular metabolic processGO:0031325940.018
negative regulation of response to stimulusGO:00485851040.018
Fly
proteolysisGO:0006508380.017
Human Mouse
regulation of rna biosynthetic processGO:20011412130.017
mitotic g2 dna damage checkpointGO:000709530.017
Fly
growthGO:00400071740.017
Worm
regulation of protein metabolic processGO:0051246560.017
protein complex assemblyGO:0006461300.017
purine ribonucleoside monophosphate catabolic processGO:000916940.017
regulation of synaptic growth at neuromuscular junctionGO:000858210.017
negative regulation of axon regenerationGO:004868140.017
regulation of catalytic activityGO:0050790550.017
reproductive processGO:0022414400.017
Worm
negative regulation of mitosisGO:004583930.017
negative regulation of rna biosynthetic processGO:1902679450.017
response to corticosteroidGO:003196010.017
rna processingGO:0006396250.017
negative regulation of nitrogen compound metabolic processGO:0051172590.016
positive regulation of cellular amine metabolic processGO:003324000.016
pancreas developmentGO:0031016840.016
peptidyl serine modificationGO:001820920.016
mitotic sister chromatid segregationGO:000007060.016
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.016
response to uvGO:000941130.016
regulation of protein import into nucleusGO:004230620.016
chemotaxisGO:00069351040.016
regulation of nervous system developmentGO:0051960900.016
modification dependent protein catabolic processGO:001994130.016
Human Mouse
regulation of rho protein signal transductionGO:003502320.016
response to woundingGO:00096111160.016
neuron developmentGO:00486662620.016
Fly
positive regulation of chromosome organizationGO:200125210.016
embryonic limb morphogenesisGO:003032620.016
pole plasm assemblyGO:000731540.016
apoptotic processGO:00069151160.016
Mouse Worm Fly
regulation of multicellular organismal developmentGO:20000262230.016
amine metabolic processGO:000930820.015
regulation of dna templated transcription elongationGO:003278430.015
intracellular transportGO:0046907320.015
response to nutrientGO:000758430.015
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.015
regulation of cell deathGO:00109411030.015
Worm Fly
golgi vesicle transportGO:004819330.015
negative regulation of dna replicationGO:000815620.015
organic acid metabolic processGO:0006082310.015
exocrine pancreas developmentGO:0031017280.015
regulation of apoptotic processGO:0042981980.015
Worm Fly
regulation of protein complex disassemblyGO:004324410.015
macromolecule biosynthetic processGO:00090592270.015
negative regulation of small gtpase mediated signal transductionGO:005105810.015
generation of neuronsGO:00486993850.015
Fly
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.015
response to hexoseGO:000974630.015
cellular response to radiationGO:007147840.015
embryonic organ developmentGO:00485683810.015
regulation of multicellular organism growthGO:004001440.015
cellular carbohydrate metabolic processGO:004426240.015
reproductionGO:0000003400.014
Worm
cytoskeleton dependent cytokinesisGO:006164030.014
regulation of reproductive processGO:200024140.014
single organism cellular localizationGO:1902580460.014
homeostatic processGO:00425921420.014
vesicle mediated transportGO:0016192220.014
Worm
cellular response to stressGO:0033554620.014
Fly
regulation of microtubule cytoskeleton organizationGO:007050730.014
neuron projection developmentGO:00311751800.014
negative regulation of synapse assemblyGO:005196420.014
cellular response to light stimulusGO:007148240.014
regulation of i kappab kinase nf kappab signalingGO:004312240.014
negative regulation of nuclear divisionGO:005178430.014
somatic muscle developmentGO:000752540.014
meiotic chromosome segregationGO:004513230.014
cell projection organizationGO:00300302840.014
carboxylic acid metabolic processGO:0019752220.014
positive regulation of secretion by cellGO:190353210.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.014
macromolecule localizationGO:0033036540.014
regulation of molecular functionGO:0065009700.014
multi organism cellular processGO:004476420.013
chromosome localizationGO:005000020.013
digestive tract morphogenesisGO:00485462310.013
response to abiotic stimulusGO:00096281220.013
negative regulation of programmed cell deathGO:0043069580.013
Worm Fly
negative regulation of protein metabolic processGO:0051248160.013
developmental growthGO:00485891660.013
regulation of cellular amine metabolic processGO:003323800.013
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.013
transcription dna templatedGO:00063511810.013
response to oxygen containing compoundGO:1901700550.013
Fly
cellular ketone metabolic processGO:0042180110.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
regulation of hydrolase activityGO:0051336280.013
negative regulation of biosynthetic processGO:0009890550.013
autophagyGO:000691440.012
angiogenesisGO:00015251580.012
regulation of cellular amino acid metabolic processGO:000652100.012
regulation of biosynthetic processGO:00098892500.012
mitotic dna damage checkpointGO:004477340.012
Fly
oocyte anterior posterior axis specificationGO:000731440.012
cellular protein catabolic processGO:004425740.012
Human Mouse
phosphorus metabolic processGO:00067931090.012
actin filament based processGO:0030029640.012
regulation of developmental processGO:00507932470.012
cellular nitrogen compound biosynthetic processGO:00442712180.012
cell substrate junction assemblyGO:000704420.012
positive regulation of chromosome segregationGO:005198410.012
regulation of macromolecule biosynthetic processGO:00105562250.012
response to topologically incorrect proteinGO:003596620.012
response to light stimulusGO:0009416460.012
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
regulation of mitosisGO:000708890.012
oxoacid metabolic processGO:0043436310.012
organelle localizationGO:0051640490.012
regulation of transcription dna templatedGO:00063552130.011
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.011
blood circulationGO:0008015870.011
positive regulation of jnk cascadeGO:004633030.011
regulation of cellular response to oxidative stressGO:190040720.011
wnt signaling pathwayGO:0016055800.011
circulatory system processGO:0003013870.011
chromosome organizationGO:0051276310.011
regulation of response to nutrient levelsGO:003210710.011
carbohydrate biosynthetic processGO:001605110.011
regulation of response to extracellular stimulusGO:003210410.011
heart processGO:0003015710.011
3 utr mediated mrna stabilizationGO:007093530.011
catabolic processGO:0009056320.011
Human Mouse Fly
cytokinetic processGO:003250620.011
negative regulation of cellular protein metabolic processGO:0032269160.011
gabaergic neuron differentiationGO:009715420.011
establishment of vesicle localizationGO:0051650240.011
neuron projection regenerationGO:0031102160.011
modification of morphology or physiology of other organismGO:003582140.011
mesenchyme developmentGO:00604851270.011
synaptic vesicle transportGO:004848910.011
phosphorylationGO:0016310690.011
regulation of neurogenesisGO:0050767870.011
regulation of peptidyl tyrosine phosphorylationGO:005073010.011
negative regulation of intracellular transportGO:003238730.011
regulation of neuron differentiationGO:0045664560.011
regulation of protein depolymerizationGO:190187910.011
negative regulation of intracellular signal transductionGO:1902532220.011
Fly
regulation of cysteine type endopeptidase activityGO:2000116210.011
stem cell differentiationGO:00488631170.010
regulation of localizationGO:00328791040.010
negative regulation of multicellular organismal processGO:0051241690.010
regulation of calcium ion transportGO:005192420.010
alternative mrna splicing via spliceosomeGO:000038010.010
response to glucoseGO:000974930.010
multicellular organismal reproductive processGO:0048609350.010
negative regulation of cellular biosynthetic processGO:0031327550.010
regulation of cellular biosynthetic processGO:00313262450.010
single fertilizationGO:000733830.010
regulation of cell activationGO:005086510.010
negative regulation of response to dna damage stimulusGO:200102130.010
cellular protein complex disassemblyGO:004362410.010
regulation of response to stressGO:0080134360.010
transcription elongation from rna polymerase ii promoterGO:000636830.010
cellular macromolecular complex assemblyGO:0034622240.010
gene silencing by rnaGO:003104740.010
positive regulation of metabolic processGO:00098931080.010
intracellular estrogen receptor signaling pathwayGO:003052030.010
cell cycle processGO:0022402530.010
Worm Fly
microtubule polymerization or depolymerizationGO:003110930.010
positive regulation of macromolecule metabolic processGO:0010604930.010

cul1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.091
nervous system diseaseDOID:86300.031
neurodegenerative diseaseDOID:128900.011
central nervous system diseaseDOID:33100.011
muscle tissue diseaseDOID:6600.011
musculoskeletal system diseaseDOID:1700.011
muscular diseaseDOID:008000000.011