Danio rerio

72 known processes

tob1a

transducer of ERBB2, 1a

(Aliases: tob1)

tob1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
hepatocyte proliferationGO:007257420.669
signal transductionGO:00071654550.504
digestive tract morphogenesisGO:00485462310.393
epithelial cell proliferation involved in liver morphogenesisGO:007257520.381
gastrulationGO:00073692080.363
macromolecule biosynthetic processGO:00090592270.363
regulation of cell communicationGO:00106462320.334
Mouse
gene expressionGO:00104672520.290
regulation of macromolecule metabolic processGO:00602553170.283
regulation of multicellular organism growthGO:004001440.223
multicellular organism growthGO:003526440.213
establishment of protein localization to organelleGO:007259440.209
Mouse
negative regulation of signal transductionGO:0009968940.203
Mouse
negative regulation of protein kinase activityGO:000646940.185
cellular response to extracellular stimulusGO:003166820.184
regulation of signal transductionGO:00099662250.172
Mouse
regionalizationGO:00030022740.169
digestive system developmentGO:00551232890.169
positive regulation of catabolic processGO:000989640.166
hematopoietic or lymphoid organ developmentGO:00485341910.160
negative regulation of autophagyGO:001050710.160
wnt signaling pathwayGO:0016055800.150
positive regulation of map kinase activityGO:004340630.149
central nervous system developmentGO:00074173870.142
cellular response to nutrient levelsGO:003166920.142
maintenance of locationGO:005123540.138
organic cyclic compound metabolic processGO:19013603010.137
insulin like growth factor receptor signaling pathwayGO:004800940.132
agingGO:000756820.127
regulation of signalingGO:00230512350.125
Mouse
digestive tract developmentGO:00485652650.125
positive regulation of cell deathGO:0010942290.123
deathGO:00162651210.118
regulation of response to stimulusGO:00485832690.117
Mouse
regulation of rna biosynthetic processGO:20011412130.115
transcription dna templatedGO:00063511810.115
immune system developmentGO:00025201910.114
cell surface receptor signaling pathwayGO:00071663250.113
alpha amino acid metabolic processGO:190160530.113
ectoderm developmentGO:000739890.112
epithalamus developmentGO:0021538100.106
single organism transportGO:00447652060.105
Mouse
immune system processGO:00023762410.105
habenula developmentGO:002198690.101
protein targeting to nucleusGO:004474430.095
Mouse
metal ion transportGO:0030001580.093
cell migrationGO:00164772370.091
cell projection organizationGO:00300302840.089
regulation of fibroblast growth factor receptor signaling pathwayGO:0040036200.089
cell morphogenesisGO:00009022890.089
eye developmentGO:00016542770.089
negative regulation of signalingGO:0023057960.088
Mouse
activation of mapk activityGO:000018730.088
brain developmentGO:00074202930.086
aromatic compound biosynthetic processGO:00194382170.084
tube morphogenesisGO:00352393490.084
establishment of localizationGO:00512342440.083
Mouse
regulation of metabolic processGO:00192223590.082
hindbrain developmentGO:0030902910.082
regulation of cellular response to growth factor stimulusGO:0090287350.080
negative regulation of response to stimulusGO:00485851040.079
Mouse
enzyme linked receptor protein signaling pathwayGO:00071671060.079
heterocycle biosynthetic processGO:00181302150.078
cell deathGO:00082191210.078
proteasomal protein catabolic processGO:001049820.077
extrinsic apoptotic signaling pathwayGO:009719130.075
positive regulation of canonical wnt signaling pathwayGO:009026340.075
estrogen metabolic processGO:000821020.075
cellular component morphogenesisGO:00329893360.074
modification dependent protein catabolic processGO:001994130.074
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.074
microtubule organizing center organizationGO:003102310.073
nuclear importGO:005117030.072
Mouse
primitive hemopoiesisGO:0060215270.071
negative regulation of cell communicationGO:0010648960.071
Mouse
positive regulation of cellular catabolic processGO:003133130.070
regulation of macromolecule biosynthetic processGO:00105562250.070
skeletal system morphogenesisGO:00487051020.069
regulation of cell deathGO:00109411030.068
single organism metabolic processGO:00447102170.068
programmed cell deathGO:00125011190.068
microtubule based processGO:0007017600.067
phagocytosisGO:000690930.066
hemopoiesisGO:00300971830.065
cellular protein catabolic processGO:004425740.064
thrombocyte differentiationGO:000257440.062
ubiquitin dependent protein catabolic processGO:000651130.060
adherens junction organizationGO:003433240.060
alcohol biosynthetic processGO:004616520.059
rna biosynthetic processGO:00327741810.059
mitotic cell cycleGO:0000278640.059
endoderm developmentGO:0007492490.059
cellular response to starvationGO:000926710.058
cell projection morphogenesisGO:00488582440.056
regulation of cell fate commitmentGO:0010453220.055
cellular macromolecule biosynthetic processGO:00346452240.054
single organism localizationGO:19025782250.053
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.053
Mouse
autophagyGO:000691440.053
locomotionGO:00400113130.053
cartilage developmentGO:0051216960.053
organic cyclic compound biosynthetic processGO:19013622230.050
single organism organelle organizationGO:19025891990.049
camera type eye developmentGO:00430102220.049
cellular macromolecule metabolic processGO:00442603910.049
ribosomal small subunit biogenesisGO:004227420.049
ameboidal type cell migrationGO:00016671430.049
response to corticosteroidGO:003196010.048
pyruvate metabolic processGO:000609010.048
cellular carbohydrate metabolic processGO:004426240.048
homeostatic processGO:00425921420.048
phosphorylationGO:0016310690.047
neuron differentiationGO:00301823530.047
regulation of apoptotic processGO:0042981980.046
lipid storageGO:001991510.046
larval developmentGO:000216420.046
positive regulation of transportGO:005105020.045
proteolysis involved in cellular protein catabolic processGO:005160330.045
central nervous system neuron differentiationGO:0021953740.045
positive regulation of programmed cell deathGO:0043068290.045
cellular response to external stimulusGO:007149620.044
cellular aromatic compound metabolic processGO:00067252950.044
cellular response to steroid hormone stimulusGO:0071383310.044
melanin metabolic processGO:000658220.043
negative regulation of intracellular signal transductionGO:1902532220.042
cellular nitrogen compound metabolic processGO:00346412900.042
regulation of cell cycleGO:0051726520.042
optic placode formationGO:000174340.042
generation of neuronsGO:00486993850.042
skeletal system developmentGO:00015011810.041
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.041
regulation of production of molecular mediator of immune responseGO:000270010.041
mesenchyme developmentGO:00604851270.041
formation of primary germ layerGO:0001704620.041
cellular amino acid metabolic processGO:000652070.041
regulation of programmed cell deathGO:00430671010.041
endoderm formationGO:0001706290.041
nucleic acid metabolic processGO:00903042440.040
response to growth factorGO:0070848390.040
ion transmembrane transportGO:0034220910.040
cellular biosynthetic processGO:00442492860.040
nucleobase containing compound metabolic processGO:00061392740.040
phagocytosis engulfmentGO:000691110.040
membrane invaginationGO:001032410.039
head developmentGO:00603223030.039
embryo development ending in birth or egg hatchingGO:00097922710.039
cell cycle g1 s phase transitionGO:004484310.039
fat soluble vitamin metabolic processGO:000677540.039
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.039
tube closureGO:006060610.039
sphingolipid biosynthetic processGO:003014820.038
single organism nuclear importGO:190259330.038
Mouse
regulation of p38mapk cascadeGO:190074410.038
protein modification processGO:00362111000.038
proteolysisGO:0006508380.038
regulation of wnt signaling pathway involved in digestive tract morphogenesisGO:200005620.038
negative regulation of protein phosphorylationGO:000193340.037
myeloid cell differentiationGO:0030099860.037
cellular response to fibroblast growth factor stimulusGO:0044344220.037
regulation of mapk cascadeGO:0043408140.037
positive regulation of response to stimulusGO:0048584800.036
negative regulation of bmp signaling pathwayGO:0030514130.036
Mouse
negative regulation of programmed cell deathGO:0043069580.035
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathwayGO:002200210.035
rna metabolic processGO:00160702190.035
positive regulation of biological processGO:00485182530.034
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.033
mesoderm formationGO:0001707430.033
protein metabolic processGO:00195381830.032
response to glucocorticoidGO:005138410.032
embryonic neurocranium morphogenesisGO:0048702150.032
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.031
hypothalamus cell differentiationGO:002197940.031
single organism cellular localizationGO:1902580460.031
Mouse
epithelial cell migrationGO:0010631250.031
tissue migrationGO:0090130370.031
positive regulation of cell adhesionGO:004578510.031
membrane organizationGO:0061024210.031
protein import into nucleusGO:000660630.030
Mouse
nucleocytoplasmic transportGO:000691340.030
Mouse
microtubule cytoskeleton organizationGO:0000226330.030
cell growthGO:0016049570.030
peptidyl serine modificationGO:001820920.030
nitrogen compound metabolic processGO:00068073190.030
transportGO:00068102200.030
Mouse
carbohydrate biosynthetic processGO:001605110.029
amine metabolic processGO:000930820.029
apoptotic signaling pathwayGO:0097190230.029
tissue regenerationGO:0042246740.029
establishment of spindle localizationGO:0051293120.029
fibroblast growth factor receptor signaling pathwayGO:0008543220.029
mesodermal cell differentiationGO:0048333210.028
homologous chromosome segregationGO:004514310.028
negative regulation of mapk cascadeGO:004340940.028
regulation of multicellular organismal developmentGO:20000262230.027
regulation of glucose transportGO:001082710.027
gland developmentGO:00487321430.027
er to golgi vesicle mediated transportGO:000688810.027
positive regulation of cellular amino acid metabolic processGO:004576400.027
myeloid cell homeostasisGO:0002262560.027
optic placode formation involved in camera type eye formationGO:004661930.027
convergent extension involved in gastrulationGO:0060027710.027
establishment or maintenance of apical basal cell polarityGO:0035088120.027
hypothalamus developmentGO:0021854140.026
regulation of protein catabolic processGO:004217610.026
regulation of biological qualityGO:00650082630.026
morphogenesis of an epitheliumGO:00020093330.025
embryonic heart tube morphogenesisGO:00031431080.025
cellular protein localizationGO:0034613200.025
Mouse
mesoderm morphogenesisGO:0048332510.025
ion transportGO:00068111140.025
cell part morphogenesisGO:00329902460.025
neuron deathGO:0070997210.025
cellular protein modification processGO:00064641000.025
regulation of cellular biosynthetic processGO:00313262450.024
positive regulation of transcription dna templatedGO:0045893570.024
signal transduction by phosphorylationGO:0023014180.024
apoptotic processGO:00069151160.024
regulation of chromosome segregationGO:005198310.024
developmental growthGO:00485891660.024
organonitrogen compound metabolic processGO:1901564740.024
modulation by virus of host morphology or physiologyGO:001904810.024
determination of heart left right asymmetryGO:00613711170.024
positive regulation of signal transductionGO:0009967560.024
symbiosis encompassing mutualism through parasitismGO:004440340.024
modification of morphology or physiology of other organismGO:003582140.023
macromolecule localizationGO:0033036540.023
Mouse
regulation of skeletal muscle fiber developmentGO:004874220.023
cellular component disassemblyGO:002241110.023
epithelium migrationGO:0090132250.022
regulation of gtpase activityGO:004308720.022
heart loopingGO:0001947940.022
protein targeting to membraneGO:000661210.022
nuclear transportGO:005116940.022
Mouse
positive regulation of cellular processGO:00485222010.022
cation transportGO:0006812810.022
organelle organizationGO:00069962270.022
bmp signaling pathwayGO:0030509520.022
response to copper ionGO:0046688130.022
regulation of ectodermal cell fate specificationGO:004266520.022
regulation of cellular metabolic processGO:00313233200.022
growthGO:00400071740.022
cellular amino acid biosynthetic processGO:000865220.021
negative regulation of phosphate metabolic processGO:0045936130.021
convergent extensionGO:00600261180.021
female sex differentiationGO:004666040.021
cellular localizationGO:0051641970.021
Mouse
spindle localizationGO:0051653120.021
regulation of cell substrate adhesionGO:001081010.021
negative regulation of biological processGO:00485193040.021
Mouse
regulation of protein metabolic processGO:0051246560.021
cellular protein metabolic processGO:00442671290.021
interaction with hostGO:005170140.021
hepaticobiliary system developmentGO:0061008980.021
modification dependent macromolecule catabolic processGO:004363230.021
regulation of biosynthetic processGO:00098892500.020
forebrain developmentGO:0030900960.020
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.020
Mouse
cytoskeleton organizationGO:0007010960.020
regulation of nucleic acid templated transcriptionGO:19035062130.020
regulation of metal ion transportGO:001095940.020
response to external stimulusGO:00096052640.020
centrosome organizationGO:005129710.020
negative regulation of cellular processGO:00485232830.020
Mouse
signal transduction in absence of ligandGO:003803410.020
regulation of epithelial cell proliferationGO:005067830.020
nephron epithelium morphogenesisGO:007208810.020
receptor internalizationGO:003162320.020
response to alkaloidGO:004327920.019
negative chemotaxisGO:005091910.019
positive regulation of immune effector processGO:000269930.019
connective tissue developmentGO:0061448990.019
liver developmentGO:0001889960.019
regulation of autophagyGO:001050630.019
adherens junction assemblyGO:003433310.019
intracellular transportGO:0046907320.019
Mouse
divalent inorganic anion homeostasisGO:007250550.019
sensory organ developmentGO:00074233930.019
macromolecule modificationGO:00434121110.019
biosynthetic processGO:00090582940.019
regulation of transcription from rna polymerase ii promoterGO:00063571140.019
cellular response to growth factor stimulusGO:0071363390.019
spinal cord anterior posterior patterningGO:002151210.019
taurine metabolic processGO:001953010.019
cellular response to chemical stimulusGO:00708871570.019
regulation of developmental processGO:00507932470.019
Mouse
regulation of anterior head developmentGO:200074220.018
regulation of dendrite developmentGO:005077330.018
negative regulation of wnt signaling pathwayGO:0030178300.018
macromolecular complex disassemblyGO:003298410.018
positive regulation of signalingGO:0023056560.018
non canonical wnt signaling pathway involved in heart developmentGO:006134120.018
response to fibroblast growth factorGO:0071774220.018
secondary metabolic processGO:001974830.018
iron ion transmembrane transportGO:003475530.018
heterocycle metabolic processGO:00464832900.017
determination of bilateral symmetryGO:00098552040.017
cell cycle processGO:0022402530.017
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.017
regulation of purine nucleotide catabolic processGO:003312120.017
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.017
response to organic substanceGO:00100331530.017
sequestering of metal ionGO:005123830.017
chordate embryonic developmentGO:00430092710.017
regulation of intracellular signal transductionGO:1902531570.017
negative regulation of fibroblast growth factor receptor signaling pathwayGO:004003760.017
organic acid metabolic processGO:0006082310.017
cellular response to estrogen stimulusGO:0071391240.017
carboxylic acid metabolic processGO:0019752220.017
epithelial cell morphogenesisGO:000338220.017
regulation of molecular functionGO:0065009700.017
anterior head developmentGO:009706520.017
single organism intracellular transportGO:1902582250.016
Mouse
muscle tissue developmentGO:00605371100.016
phenol containing compound biosynthetic processGO:004618940.016
stem cell differentiationGO:00488631170.016
positive regulation of cell divisionGO:005178120.016
negative regulation of sequestering of calcium ionGO:005128340.016
response to nutrientGO:000758430.016
organelle localizationGO:0051640490.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
negative regulation of kinase activityGO:003367340.016
male meiosisGO:000714020.016
kupffer s vesicle developmentGO:0070121500.016
cellular response to stressGO:0033554620.016
positive regulation of nucleobase containing compound metabolic processGO:0045935690.016
positive regulation of muscle cell differentiationGO:005114910.016
negative regulation of cell deathGO:0060548600.016
smooth muscle tissue developmentGO:004874510.016
mapk cascadeGO:0000165180.016
homeostasis of number of cellsGO:0048872620.015
meiotic chromosome segregationGO:004513230.015
regulation of carbohydrate metabolic processGO:000610940.015
regulation of nucleoside metabolic processGO:000911820.015
positive regulation of macromolecule biosynthetic processGO:0010557590.015
positive regulation of multi organism processGO:004390230.015
cell projection assemblyGO:0030031640.015
multicellular organismal metabolic processGO:004423620.015
regulation of bone mineralizationGO:003050020.015
protein phosphorylationGO:0006468470.015
embryonic organ morphogenesisGO:00485622740.015
gall bladder developmentGO:006101010.015
release of sequestered calcium ion into cytosolGO:005120930.015
ovulation cycleGO:004269820.015
gtp metabolic processGO:004603940.015
positive regulation of nucleic acid templated transcriptionGO:1903508570.015
regulation of stem cell differentiationGO:200073640.015
peptidyl serine phosphorylationGO:001810510.015
cellular nitrogen compound biosynthetic processGO:00442712180.015
cell fate specificationGO:0001708680.015
regulation of epithelial to mesenchymal transitionGO:001071730.014
meiotic nuclear divisionGO:000712640.014
viral processGO:001603210.014
lateral line developmentGO:0048882660.014
mitotic cell cycle processGO:1903047480.014
epiboly involved in gastrulation with mouth forming secondGO:0055113350.014
regulation of cellular protein metabolic processGO:0032268520.014
regulation of multicellular organismal processGO:00512392770.014
Mouse
response to steroid hormoneGO:0048545350.014
meiosis iGO:000712710.014
regulation of nucleotide catabolic processGO:003081120.014
negative regulation of cellular metabolic processGO:0031324770.014
Mouse
organic substance biosynthetic processGO:19015762890.014
positive regulation of nucleoside metabolic processGO:004597910.014
negative regulation of protein serine threonine kinase activityGO:007190120.014
regulation of primary metabolic processGO:00800903110.014
nucleic acid templated transcriptionGO:00976591810.014
ovarian follicle developmentGO:000154120.014
negative regulation of synapse assemblyGO:005196420.014
zymogen activationGO:003163830.014
regulation of response to nutrient levelsGO:003210710.014
regulation of endocrine processGO:004406020.014
regulation of mitotic cell cycleGO:0007346250.014
cell substrate adhesionGO:003158940.013
embryonic hemopoiesisGO:0035162530.013
organism emergence from protective structureGO:007168440.013
regulation of cellular amine metabolic processGO:003323800.013
cell cycleGO:0007049930.013
transcription from rna polymerase ii promoterGO:0006366800.013
wound healingGO:0042060900.013
synaptic growth at neuromuscular junctionGO:005112420.013
positive regulation of rna biosynthetic processGO:1902680570.013
hepatic duct developmentGO:006101120.013
regulation of myeloid leukocyte differentiationGO:000276150.013
cerebellum morphogenesisGO:0021587100.013
branched chain amino acid metabolic processGO:000908110.013
energy reserve metabolic processGO:000611220.013
cellular modified amino acid metabolic processGO:000657530.013
intracellular signal transductionGO:0035556850.013
hatchingGO:003518840.013
positive regulation of cellular carbohydrate metabolic processGO:001067610.013
gastrulation with mouth forming secondGO:0001702440.013
regulation of cellular carbohydrate metabolic processGO:001067540.013
regulation of lipid transportGO:003236840.013
mitotic nuclear divisionGO:0007067180.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.013
positive regulation of protein complex assemblyGO:003133420.013
regulation of rna metabolic processGO:00512522240.013
positive regulation of carbohydrate metabolic processGO:004591310.012
regenerationGO:0031099910.012
cell morphogenesis involved in differentiationGO:00009041950.012
protein importGO:001703830.012
Mouse
cellular component movementGO:00069283350.012
negative regulation of epithelial cell proliferationGO:005068010.012
oxoacid metabolic processGO:0043436310.012
erythrocyte homeostasisGO:0034101550.012
protein localizationGO:0008104400.012
Mouse
limbic system developmentGO:0021761160.012
negative regulation of cellular catabolic processGO:003133030.012
nephron tubule morphogenesisGO:007207810.012
protein polyubiquitinationGO:000020940.012
cell junction maintenanceGO:003433120.012
neuron developmentGO:00486662620.012
rhombomere 6 developmentGO:002157240.012
regulation of nitrogen compound metabolic processGO:00511712510.012
regulation of circadian rhythmGO:004275240.012
steroid hormone secretionGO:003592910.012
cell matrix adhesionGO:000716040.012
multicellular organismal response to stressGO:003355520.011
localization of cellGO:00516742440.011
cellular amine metabolic processGO:004410620.011
spinal cord developmentGO:0021510460.011
regulation of proteolysisGO:0030162240.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
superoxide metabolic processGO:000680120.011
regulation of canonical wnt signaling pathwayGO:0060828340.011
positive regulation of cellular metabolic processGO:0031325940.011
rhombomere 5 developmentGO:002157140.011
establishment of localization in cellGO:0051649770.011
Mouse
meiotic cell cycle processGO:190304630.011
negative regulation of apoptotic processGO:0043066550.011
intestinal cholesterol absorptionGO:003029920.011
regulation of wnt signaling pathway calcium modulating pathwayGO:000859130.011
regulation of jun kinase activityGO:004350630.011
regulation of cell growthGO:0001558290.011
organic hydroxy compound biosynthetic processGO:190161760.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
positive regulation of cytoskeleton organizationGO:005149530.011
carbohydrate homeostasisGO:003350010.011
positive regulation of epithelial cell proliferationGO:005067910.011
establishment of cell polarityGO:0030010180.011
mitochondrial transportGO:000683920.011
blood vessel developmentGO:00015682460.011
response to carbohydrateGO:000974330.011
chromosome segregationGO:0007059120.011
response to chemicalGO:00422213200.011
spindle assemblyGO:005122520.011
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.011
protein localization to plasma membraneGO:007265910.011
pathway restricted smad protein phosphorylationGO:006038910.011
specification of axis polarityGO:006500140.011
non canonical wnt signaling pathwayGO:0035567130.011
endodermal cell fate specificationGO:0001714170.011
cell fate commitmentGO:0045165990.011
heart developmentGO:00075073130.011
positive regulation of cellular component biogenesisGO:004408930.011
regulation of establishment of planar polarityGO:009017540.011
telomere organizationGO:003220010.011
embryonic organ developmentGO:00485683810.011
somitogenesisGO:0001756870.011
regulation of protein phosphorylationGO:0001932180.010
negative regulation of dna metabolic processGO:005105340.010
adult behaviorGO:003053420.010
fat soluble vitamin biosynthetic processGO:004236220.010
female germ line stem cell maintenanceGO:003609910.010
response to stressGO:00069502630.010
skin developmentGO:0043588540.010
positive regulation of biosynthetic processGO:0009891680.010
intrahepatic bile duct developmentGO:0035622110.010
response to light stimulusGO:0009416460.010
developmental maturationGO:0021700340.010
positive regulation of cell cycleGO:004578730.010
atrioventricular valve developmentGO:0003171110.010
small molecule metabolic processGO:0044281770.010
epithelial cell differentiationGO:00308551160.010
cellular sodium ion homeostasisGO:000688310.010
positive regulation of production of molecular mediator of immune responseGO:000270210.010
negative regulation of metabolic processGO:0009892860.010
Mouse
cell substrate junction assemblyGO:000704420.010
cell aggregationGO:009874330.010

tob1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.085
disease of metabolismDOID:001466700.085
musculoskeletal system diseaseDOID:1700.021
connective tissue diseaseDOID:6500.021
disease of anatomical entityDOID:700.021
bone diseaseDOID:008000100.018
disease of mental healthDOID:15000.015
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011