Danio rerio

17 known processes

angptl2

angiopoietin-like 2

(Aliases: wu:fc41g02)

angptl2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to external stimulusGO:00096052640.820
blood vessel developmentGO:00015682460.603
negative regulation of biological processGO:00485193040.572
locomotionGO:00400113130.463
brain developmentGO:00074202930.456
regulation of response to stimulusGO:00485832690.449
cell fate commitmentGO:0045165990.437
regionalizationGO:00030022740.427
neuron projection developmentGO:00311751800.418
defense responseGO:0006952470.414
chemotaxisGO:00069351040.413
response to stressGO:00069502630.397
Zebrafish
negative regulation of cellular processGO:00485232830.356
cellular component morphogenesisGO:00329893360.354
regulation of cellular ketone metabolic processGO:001056570.351
cell morphogenesisGO:00009022890.334
cell surface receptor signaling pathwayGO:00071663250.326
response to chemicalGO:00422213200.326
response to organic substanceGO:00100331530.321
cellular component movementGO:00069283350.303
signal transductionGO:00071654550.297
hemopoiesisGO:00300971830.289
regulation of cell differentiationGO:00455951420.285
response to nutrientGO:000758430.283
immune system processGO:00023762410.278
nitrogen compound metabolic processGO:00068073190.277
multicellular organismal metabolic processGO:004423620.261
generation of neuronsGO:00486993850.256
branched chain amino acid metabolic processGO:000908110.254
chordate embryonic developmentGO:00430092710.252
positive regulation of cellular processGO:00485222010.250
positive regulation of response to stimulusGO:0048584800.242
defense response to other organismGO:0098542330.233
cell part morphogenesisGO:00329902460.229
amine metabolic processGO:000930820.224
cellular amino acid metabolic processGO:000652070.221
neuron differentiationGO:00301823530.221
regulation of multicellular organismal processGO:00512392770.214
taurine metabolic processGO:001953010.214
skeletal system developmentGO:00015011810.213
positive regulation of cellular amino acid metabolic processGO:004576400.205
tube morphogenesisGO:00352393490.204
digestive tract morphogenesisGO:00485462310.203
axon developmentGO:00615641660.202
regulation of cellular amine metabolic processGO:003323800.199
cell projection morphogenesisGO:00488582440.191
localization of cellGO:00516742440.191
cellular amine metabolic processGO:004410620.184
negative regulation of cell growthGO:003030870.183
regulation of response to stressGO:0080134360.182
positive regulation of signalingGO:0023056560.172
regulation of macromolecule metabolic processGO:00602553170.171
head developmentGO:00603223030.165
single organism metabolic processGO:00447102170.163
Zebrafish
regulation of signalingGO:00230512350.162
cell morphogenesis involved in neuron differentiationGO:00486671630.160
cell growthGO:0016049570.158
negative regulation of cell communicationGO:0010648960.158
regulation of developmental processGO:00507932470.154
regenerationGO:0031099910.149
regulation of cellular amino acid metabolic processGO:000652100.149
cellular macromolecule metabolic processGO:00442603910.147
regulation of epithelial cell proliferationGO:005067830.144
cellular ketone metabolic processGO:0042180110.141
regulation of stem cell differentiationGO:200073640.141
epithelial tube morphogenesisGO:00605621480.137
cell projection organizationGO:00300302840.136
central nervous system developmentGO:00074173870.135
alpha amino acid metabolic processGO:190160530.134
response to woundingGO:00096111160.134
Zebrafish
organonitrogen compound metabolic processGO:1901564740.131
eye developmentGO:00016542770.130
positive regulation of biological processGO:00485182530.129
regulation of primary metabolic processGO:00800903110.128
somitogenesisGO:0001756870.126
sensory organ developmentGO:00074233930.125
larval developmentGO:000216420.124
embryonic organ developmentGO:00485683810.122
sensory organ morphogenesisGO:00905962000.122
regulation of cellular metabolic processGO:00313233200.121
cellular response to hormone stimulusGO:0032870390.121
phosphorus metabolic processGO:00067931090.120
angiogenesisGO:00015251580.118
collagen metabolic processGO:003296320.117
regulation of signal transductionGO:00099662250.116
skeletal system morphogenesisGO:00487051020.115
protein modification processGO:00362111000.114
protein metabolic processGO:00195381830.114
Zebrafish
macromolecule modificationGO:00434121110.113
regulation of cell communicationGO:00106462320.111
segmentationGO:0035282970.111
regulation of peptidyl tyrosine phosphorylationGO:005073010.109
response to lipidGO:0033993600.108
digestive system developmentGO:00551232890.108
axonogenesisGO:00074091520.106
regulation of metabolic processGO:00192223590.106
cellular protein metabolic processGO:00442671290.106
cartilage developmentGO:0051216960.104
regulation of nervous system developmentGO:0051960900.103
bone developmentGO:0060348140.103
cellular protein modification processGO:00064641000.103
organic cyclic compound metabolic processGO:19013603010.101
response to oxygen containing compoundGO:1901700550.100
regulation of synapse organizationGO:005080730.100
embryo development ending in birth or egg hatchingGO:00097922710.100
glial cell migrationGO:000834730.099
regulation of cell activationGO:005086510.097
cellular modified amino acid metabolic processGO:000657530.095
negative regulation of response to stimulusGO:00485851040.095
cell migrationGO:00164772370.091
growthGO:00400071740.090
neuron developmentGO:00486662620.089
morphogenesis of an epitheliumGO:00020093330.089
synaptic growth at neuromuscular junctionGO:005112420.089
regulation of synapse assemblyGO:005196330.088
immune responseGO:0006955280.087
regulation of reproductive processGO:200024140.087
mesenchymal cell differentiationGO:0048762870.087
leukocyte proliferationGO:007066110.087
eye morphogenesisGO:00485921440.086
organic substance biosynthetic processGO:19015762890.086
cellular component biogenesisGO:00440851780.086
positive regulation of nervous system developmentGO:0051962250.085
positive regulation of nitrogen compound metabolic processGO:0051173690.084
cell morphogenesis involved in differentiationGO:00009041950.084
activation of mapk activityGO:000018730.081
positive regulation of cellular amine metabolic processGO:003324000.076
heterocycle metabolic processGO:00464832900.075
gland developmentGO:00487321430.075
biosynthetic processGO:00090582940.074
regulation of cellular component organizationGO:0051128860.073
positive regulation of signal transductionGO:0009967560.073
response to vitaminGO:003327330.073
regulation of endothelial cell proliferationGO:000193610.073
cellular nitrogen compound metabolic processGO:00346412900.073
cell motilityGO:00488702440.072
cellular response to organic substanceGO:00713101050.072
phosphorylationGO:0016310690.072
taxisGO:00423301090.071
system processGO:00030081850.071
anterior posterior pattern specificationGO:00099521520.071
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.071
transportGO:00068102200.070
cellular component assemblyGO:00226071700.069
heart developmentGO:00075073130.066
regulation of multicellular organismal developmentGO:20000262230.066
carboxylic acid metabolic processGO:0019752220.065
intracellular signal transductionGO:0035556850.064
positive regulation of neurogenesisGO:0050769240.063
regulation of biological qualityGO:00650082630.063
Zebrafish
response to biotic stimulusGO:0009607970.063
cellular response to extracellular stimulusGO:003166820.063
embryonic skeletal system morphogenesisGO:0048704930.063
immune system developmentGO:00025201910.063
nucleobase containing compound biosynthetic processGO:00346542050.063
regulation of gene expressionGO:00104682650.063
axon guidanceGO:0007411860.062
organic acid metabolic processGO:0006082310.062
regulation of intracellular signal transductionGO:1902531570.061
outflow tract morphogenesisGO:000315110.060
negative regulation of cell differentiationGO:0045596460.060
regulation of cell developmentGO:00602841000.059
heart morphogenesisGO:00030071560.059
developmental growth involved in morphogenesisGO:0060560860.058
positive regulation of nucleic acid templated transcriptionGO:1903508570.058
regulation of localizationGO:00328791040.058
negative regulation of signalingGO:0023057960.058
negative regulation of multicellular organismal processGO:0051241690.057
negative regulation of chemotaxisGO:005092240.057
regulation of nitrogen compound metabolic processGO:00511712510.056
regulation of nucleobase containing compound metabolic processGO:00192192500.056
hepaticobiliary system developmentGO:0061008980.056
organelle organizationGO:00069962270.056
liver developmentGO:0001889960.056
response to glucocorticoidGO:005138410.055
positive regulation of macromolecule metabolic processGO:0010604930.055
determination of dorsal ventral asymmetryGO:0048262340.054
cellular response to chemical stimulusGO:00708871570.054
cellular biosynthetic processGO:00442492860.054
connective tissue developmentGO:0061448990.054
inositol lipid mediated signalingGO:004801720.054
protein phosphorylationGO:0006468470.054
bone morphogenesisGO:0060349110.053
symbiosis encompassing mutualism through parasitismGO:004440340.052
multi organism processGO:00517041340.052
oxoacid metabolic processGO:0043436310.051
receptor internalizationGO:003162320.051
mesenchyme developmentGO:00604851270.050
transmission of nerve impulseGO:0019226190.050
positive regulation of canonical wnt signaling pathwayGO:009026340.049
phosphate containing compound metabolic processGO:00067961080.049
neuron projection morphogenesisGO:00488121610.049
cellular response to endogenous stimulusGO:0071495680.048
regulation of phosphorus metabolic processGO:0051174430.048
negative regulation of leukocyte differentiationGO:190210610.048
embryonic heart tube developmentGO:00350501330.048
negative regulation of developmental processGO:0051093650.047
regulation of macromolecule biosynthetic processGO:00105562250.047
enzyme linked receptor protein signaling pathwayGO:00071671060.047
response to ketoneGO:190165410.046
regulation of cellular macromolecule biosynthetic processGO:20001122220.046
regulation of immune system processGO:0002682340.046
trabecula formationGO:006034320.046
developmental growthGO:00485891660.045
negative regulation of myeloid cell differentiationGO:004563810.045
somite developmentGO:0061053960.045
negative regulation of metabolic processGO:0009892860.045
determination of ventral identityGO:0048264210.045
cellular response to nutrient levelsGO:003166920.045
tissue remodelingGO:004877140.045
mesenchymal cell developmentGO:0014031780.045
determination of bilateral symmetryGO:00098552040.044
negative regulation of signal transductionGO:0009968940.044
gene expressionGO:00104672520.044
regulation of cytoplasmic transportGO:190364940.044
regulation of rna biosynthetic processGO:20011412130.044
defense response to fungusGO:005083220.044
response to endogenous stimulusGO:0009719830.043
bmp signaling pathwayGO:0030509520.043
agingGO:000756820.043
regulation of protein metabolic processGO:0051246560.043
regulation of biosynthetic processGO:00098892500.043
negative regulation of immune system processGO:000268370.043
cell deathGO:00082191210.042
positive regulation of cell activationGO:005086710.042
sprouting angiogenesisGO:0002040530.042
cellular response to oxygen containing compoundGO:1901701200.042
blood vessel morphogenesisGO:00485142160.041
cell fate specificationGO:0001708680.041
regulation of rna metabolic processGO:00512522240.041
positive regulation of epithelial cell proliferationGO:005067910.041
muscle cell developmentGO:00550011150.041
positive regulation of cell communicationGO:0010647560.040
regulation of epithelial to mesenchymal transitionGO:001071730.040
negative regulation of cell deathGO:0060548600.040
cellular macromolecule biosynthetic processGO:00346452240.039
regulation of protein import into nucleusGO:004230620.039
mononuclear cell proliferationGO:003294310.039
regulation of response to external stimulusGO:0032101310.039
positive regulation of metabolic processGO:00098931080.039
camera type eye morphogenesisGO:00485931080.039
positive regulation of map kinase activityGO:004340630.038
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.038
interspecies interaction between organismsGO:004441940.038
gliogenesisGO:0042063450.037
single organism nuclear importGO:190259330.037
positive regulation of intracellular signal transductionGO:1902533150.037
multicellular organism growthGO:003526440.037
determination of left right symmetryGO:00073681790.037
establishment of blood brain barrierGO:006085620.036
regulation of metal ion transportGO:001095940.036
female gonad developmentGO:000858540.036
response to organic cyclic compoundGO:0014070510.036
negative regulation of epithelial cell proliferationGO:005068010.036
stem cell differentiationGO:00488631170.036
forebrain developmentGO:0030900960.036
determination of heart left right asymmetryGO:00613711170.036
hematopoietic or lymphoid organ developmentGO:00485341910.035
positive regulation of developmental processGO:0051094500.035
response to estrogenGO:0043627270.035
rna biosynthetic processGO:00327741810.035
muscle cell migrationGO:001481240.034
organic cyclic compound biosynthetic processGO:19013622230.034
regulation of protein localization to nucleusGO:190018020.034
regulation of neurogenesisGO:0050767870.034
mesoderm developmentGO:0007498880.034
positive regulation of endothelial cell proliferationGO:000193810.034
response to steroid hormoneGO:0048545350.034
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.033
regulation of growthGO:0040008420.033
response to external biotic stimulusGO:0043207970.033
regulation of cell motilityGO:2000145460.032
retinal ganglion cell axon guidanceGO:0031290350.032
vasculature developmentGO:00019442780.032
regulation of extrinsic apoptotic signaling pathwayGO:200123630.032
phosphatidylinositol 3 kinase signalingGO:001406520.032
response to other organismGO:0051707970.032
cellular aromatic compound metabolic processGO:00067252950.032
regulation of cell growthGO:0001558290.031
protein importGO:001703830.031
negative regulation of macromolecule metabolic processGO:0010605760.031
response to monosaccharideGO:003428430.031
immune response regulating signaling pathwayGO:000276450.030
hindbrain developmentGO:0030902910.030
gastrulationGO:00073692080.030
response to corticosteroidGO:003196010.030
regulation of establishment of protein localizationGO:007020140.029
cellular nitrogen compound biosynthetic processGO:00442712180.029
negative regulation of nuclear divisionGO:005178430.029
developmental cell growthGO:0048588520.029
regulation of locomotionGO:0040012550.029
regulation of cellular protein metabolic processGO:0032268520.029
response to fatty acidGO:007054250.029
female sex differentiationGO:004666040.029
cellular response to external stimulusGO:007149620.029
leukocyte differentiationGO:0002521250.028
regulation of transcription from rna polymerase ii promoterGO:00063571140.028
action potentialGO:0001508190.028
ph reductionGO:004585110.028
stem cell maintenanceGO:001982740.028
apical junction assemblyGO:004329710.028
lymphocyte proliferationGO:004665110.028
negative regulation of biosynthetic processGO:0009890550.028
negative regulation of stem cell differentiationGO:200073720.028
skeletal muscle organ developmentGO:0060538780.028
morphogenesis of embryonic epitheliumGO:0016331300.028
regulation of developmental growthGO:0048638380.028
negative regulation of map kinase activityGO:004340720.027
axon extensionGO:0048675450.027
ameboidal type cell migrationGO:00016671430.027
establishment of protein localization to organelleGO:007259440.027
epithelial to mesenchymal transitionGO:0001837210.027
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.027
tube closureGO:006060610.027
regulation of transporter activityGO:003240920.026
rna metabolic processGO:00160702190.026
regulation of bone mineralizationGO:003050020.026
regulation of inflammatory responseGO:005072720.026
positive regulation of immune effector processGO:000269930.026
oocyte maturationGO:000155640.026
erk1 and erk2 cascadeGO:007037140.026
behaviorGO:0007610740.026
specification of symmetryGO:00097992040.026
positive regulation of catabolic processGO:000989640.026
cellular response to radiationGO:007147840.026
regulation of sodium ion transportGO:000202820.026
single organism localizationGO:19025782250.026
positive regulation of cellular metabolic processGO:0031325940.026
cellular response to lipidGO:0071396390.025
regulation of cell migrationGO:0030334400.025
regulation of bindingGO:005109830.025
maintenance of locationGO:005123540.025
deathGO:00162651210.025
positive regulation of protein metabolic processGO:0051247230.024
trabecula morphogenesisGO:006138320.024
peptidyl amino acid modificationGO:0018193160.024
stem cell developmentGO:0048864820.024
negative regulation of cytokine productionGO:000181810.024
peptide transportGO:001583310.024
positive regulation of multicellular organismal processGO:0051240520.024
positive regulation of blood circulationGO:190352420.024
embryonic cranial skeleton morphogenesisGO:0048701900.024
morphogenesis of a branching epitheliumGO:0061138160.024
skeletal muscle tissue developmentGO:0007519670.024
nucleic acid templated transcriptionGO:00976591810.024
response to glucoseGO:000974930.024
protein import into nucleusGO:000660630.024
embryonic pattern specificationGO:0009880440.024
phagocytosisGO:000690930.023
cell proliferationGO:0008283800.023
primary neural tube formationGO:001402010.023
fin regenerationGO:0031101510.023
regulation of extent of cell growthGO:0061387290.023
regulation of protein targetingGO:190353320.023
nuclear importGO:005117030.023
cellular response to prostaglandin stimulusGO:007137930.023
regulation of nucleic acid templated transcriptionGO:19035062130.023
nuclear transportGO:005116940.023
endoderm developmentGO:0007492490.023
heterocycle biosynthetic processGO:00181302150.022
neuron projection extensionGO:1990138450.022
regulation of multicellular organism growthGO:004001440.022
response to carbohydrateGO:000974330.022
dorsal ventral pattern formationGO:00099531250.022
digestive tract developmentGO:00485652650.022
synapse assemblyGO:000741690.022
negative regulation of cell morphogenesis involved in differentiationGO:001077180.022
embryonic skeletal system developmentGO:0048706970.022
peptidyl serine modificationGO:001820920.021
regulation of phosphorylationGO:0042325260.021
gtp metabolic processGO:004603940.021
negative chemotaxisGO:005091910.021
positive regulation of cellular catabolic processGO:003133130.021
skin developmentGO:0043588540.021
cell chemotaxisGO:0060326170.021
protein targeting to nucleusGO:004474430.021
negative regulation of peptidase activityGO:0010466100.021
transcription from rna polymerase ii promoterGO:0006366800.021
innate immune responseGO:0045087130.021
regulation of anatomical structure morphogenesisGO:00226031300.021
regulation of intracellular protein transportGO:003315730.021
macromolecule biosynthetic processGO:00090592270.021
regulation of cellular biosynthetic processGO:00313262450.020
camera type eye developmentGO:00430102220.020
epithelium migrationGO:0090132250.020
spinal cord developmentGO:0021510460.020
neuron projection guidanceGO:0097485860.020
regulation of jak stat cascadeGO:004642530.020
nucleocytoplasmic transportGO:000691340.020
development of primary female sexual characteristicsGO:004654540.020
negative regulation of gene expressionGO:0010629650.020
b cell activationGO:004211320.020
heart joggingGO:0003146400.020
axis specificationGO:0009798430.020
positive regulation of biosynthetic processGO:0009891680.020
regulation of protein transportGO:005122330.020
aromatic compound biosynthetic processGO:00194382170.020
regulation of hormone secretionGO:004688320.020
small molecule metabolic processGO:0044281770.020
regulation of nucleocytoplasmic transportGO:004682220.020
cellular response to lipopolysaccharideGO:007122230.020
tissue regenerationGO:0042246740.019
peptidyl tyrosine modificationGO:001821250.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.019
positive regulation of cell divisionGO:005178120.019
guanosine containing compound metabolic processGO:190106840.019
single organism organelle organizationGO:19025891990.019
regulation of biomineral tissue developmentGO:007016720.019
regulation of cellular component movementGO:0051270550.019
positive regulation of phosphate metabolic processGO:0045937210.019
cellular response to steroid hormone stimulusGO:0071383310.019
positive regulation of gtp catabolic processGO:003312610.019
negative regulation of sequestering of calcium ionGO:005128340.019
production of molecular mediator of immune responseGO:000244020.019
reactive nitrogen species metabolic processGO:200105700.019
signal transduction by phosphorylationGO:0023014180.019
multicellular organismal response to stressGO:003355520.019
response to virusGO:0009615210.019
single organism cellular localizationGO:1902580460.019
purine nucleoside monophosphate catabolic processGO:000912840.019
peptidyl tyrosine phosphorylationGO:001810850.018
pigmentationGO:0043473850.018
cellular response to oxygen levelsGO:007145310.018
mesoderm morphogenesisGO:0048332510.018
cartilage development involved in endochondral bone morphogenesisGO:006035180.018
organonitrogen compound biosynthetic processGO:1901566470.018
response to alkaloidGO:004327920.018
sympathetic nervous system developmentGO:004848530.018
odontogenesis of dentin containing toothGO:004247510.018
multicellular organismal macromolecule metabolic processGO:004425920.018
response to abiotic stimulusGO:00096281220.018
neurotransmitter transportGO:000683620.018
positive regulation of jak stat cascadeGO:004642720.018
regulation of protein modification processGO:0031399290.018
positive regulation of protein kinase b signalingGO:005189710.018
regulation of transcription dna templatedGO:00063552130.018
multicellular organismal signalingGO:0035637220.018
collagen biosynthetic processGO:003296420.017
positive regulation of stress activated mapk cascadeGO:003287430.017
negative regulation of secretion by cellGO:190353120.017
bone remodelingGO:004684920.017
multicellular organismal homeostasisGO:0048871290.017
positive regulation of i kappab kinase nf kappab signalingGO:004312330.017
stem cell proliferationGO:007208940.017
lipid storageGO:001991510.017
regulation of bmp signaling pathwayGO:0030510390.017
regulation of cell deathGO:00109411030.017
negative regulation of cell developmentGO:0010721260.017
notochord developmentGO:0030903540.017
positive regulation of translationGO:004572710.017
positive regulation of dna metabolic processGO:005105410.017
regulation of catalytic activityGO:0050790550.017
negative regulation of myeloid leukocyte differentiationGO:000276210.017
embryonic heart tube morphogenesisGO:00031431080.017
convergent extensionGO:00600261180.017
neural crest cell differentiationGO:0014033720.017
intestinal cholesterol absorptionGO:003029920.017
negative regulation of endopeptidase activityGO:0010951100.017
negative regulation of defense responseGO:003134820.017
regulation of protein bindingGO:004339330.016
peptidyl threonine modificationGO:001821010.016
endocrine system developmentGO:0035270650.016
positive regulation of cell proliferationGO:0008284150.016
modulation by virus of host morphology or physiologyGO:001904810.016
melanin metabolic processGO:000658220.016
response to extracellular stimulusGO:0009991100.016
cell matrix adhesionGO:000716040.016
regulation of nucleoside metabolic processGO:000911820.016
multi organism cellular processGO:004476420.016
regulation of chondrocyte differentiationGO:003233010.016
negative regulation of neutrophil migrationGO:190262330.016
osteoclast differentiationGO:003031610.016
positive regulation of cellular biosynthetic processGO:0031328680.016
macromolecular complex subunit organizationGO:0043933740.016
response to hormoneGO:0009725480.016
positive regulation of nucleoside metabolic processGO:004597910.016
cellular response to stressGO:0033554620.016
negative regulation of mitosisGO:004583930.016
negative regulation of immune responseGO:005077720.015
positive regulation of immune system processGO:0002684170.015
synaptic target recognitionGO:000803910.015
muscle tissue developmentGO:00605371100.015
endodermal cell differentiationGO:0035987190.015
embryonic organ morphogenesisGO:00485622740.015

angptl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
sensory system diseaseDOID:005015500.043
nervous system diseaseDOID:86300.043
eye diseaseDOID:561400.043
eye and adnexa diseaseDOID:149200.043
lipid metabolism disorderDOID:314600.026
inherited metabolic disorderDOID:65500.026
disease of metabolismDOID:001466700.026
musculoskeletal system diseaseDOID:1700.022
connective tissue diseaseDOID:6500.022
bone diseaseDOID:008000100.022