Danio rerio

25 known processes

unc45a

unc-45 homolog A (C. elegans)

(Aliases: zgc:112031)

unc45a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
blood vessel morphogenesisGO:00485142160.800
immune system developmentGO:00025201910.754
embryonic organ morphogenesisGO:00485622740.743
chordate embryonic developmentGO:00430092710.675
embryonic organ developmentGO:00485683810.652
vasculature developmentGO:00019442780.616
neuron differentiationGO:00301823530.543
brain developmentGO:00074202930.535
embryonic skeletal system morphogenesisGO:0048704930.518
embryonic cranial skeleton morphogenesisGO:0048701900.513
hemopoiesisGO:00300971830.455
negative regulation of biological processGO:00485193040.444
neuron developmentGO:00486662620.437
blood vessel developmentGO:00015682460.385
generation of neuronsGO:00486993850.368
digestive tract developmentGO:00485652650.359
cell projection morphogenesisGO:00488582440.359
negative regulation of cellular processGO:00485232830.343
central nervous system developmentGO:00074173870.339
hematopoietic or lymphoid organ developmentGO:00485341910.323
epidermis developmentGO:0008544480.320
neuron projection developmentGO:00311751800.319
larval developmentGO:000216420.319
inner ear developmentGO:00488391260.297
skeletal system morphogenesisGO:00487051020.295
macromolecular complex subunit organizationGO:0043933740.293
Worm
forebrain developmentGO:0030900960.291
axon developmentGO:00615641660.287
regulation of multicellular organismal developmentGO:20000262230.284
connective tissue developmentGO:0061448990.266
cell morphogenesis involved in differentiationGO:00009041950.265
epithelial cell differentiationGO:00308551160.253
embryonic viscerocranium morphogenesisGO:0048703520.245
cellular component morphogenesisGO:00329893360.241
Zebrafish Worm
maintenance of locationGO:005123540.241
cell morphogenesisGO:00009022890.223
ear developmentGO:00435831270.218
striated muscle tissue developmentGO:00147061100.215
Zebrafish
hematopoietic stem cell differentiationGO:0060218200.215
cell morphogenesis involved in neuron differentiationGO:00486671630.214
cell projection organizationGO:00300302840.214
cell surface receptor signaling pathwayGO:00071663250.213
heart developmentGO:00075073130.207
Zebrafish
skin developmentGO:0043588540.201
stem cell developmentGO:0048864820.200
cell part morphogenesisGO:00329902460.198
cell fate commitmentGO:0045165990.197
head developmentGO:00603223030.195
inorganic ion transmembrane transportGO:0098660570.195
negative regulation of epithelial cell proliferationGO:005068010.194
endothelial cell differentiationGO:0045446200.193
morphogenesis of a branching structureGO:0001763210.193
digestive tract morphogenesisGO:00485462310.190
tube morphogenesisGO:00352393490.186
regulation of anatomical structure morphogenesisGO:00226031300.184
morphogenesis of an epitheliumGO:00020093330.181
cellular component movementGO:00069283350.179
axon guidanceGO:0007411860.173
axonogenesisGO:00074091520.168
axon extensionGO:0048675450.167
digestive system developmentGO:00551232890.166
signal transductionGO:00071654550.162
inner ear receptor cell developmentGO:0060119200.161
developmental growth involved in morphogenesisGO:0060560860.156
hematopoietic progenitor cell differentiationGO:0002244230.156
regulation of cell communicationGO:00106462320.154
meiotic nuclear divisionGO:000712640.153
stem cell differentiationGO:00488631170.152
circulatory system processGO:0003013870.146
patterning of blood vesselsGO:0001569150.143
aromatic compound biosynthetic processGO:00194382170.143
regulation of neurogenesisGO:0050767870.141
eye developmentGO:00016542770.138
epithelial cell developmentGO:0002064420.136
heart morphogenesisGO:00030071560.136
mechanoreceptor differentiationGO:0042490370.134
inner ear morphogenesisGO:0042472630.131
hair cell differentiationGO:0035315320.130
immune system processGO:00023762410.130
sensory organ developmentGO:00074233930.129
regionalizationGO:00030022740.128
epithelial cell morphogenesisGO:000338220.127
regulation of vascular endothelial growth factor receptor signaling pathwayGO:003094780.126
regulation of response to stimulusGO:00485832690.124
regulation of multicellular organismal processGO:00512392770.122
embryo development ending in birth or egg hatchingGO:00097922710.120
Worm
mesenchymal cell differentiationGO:0048762870.119
embryonic skeletal system developmentGO:0048706970.118
cilium morphogenesisGO:0060271850.118
organic substance biosynthetic processGO:19015762890.113
enzyme linked receptor protein signaling pathwayGO:00071671060.113
epidermal cell differentiationGO:0009913360.111
camera type eye developmentGO:00430102220.110
inner ear receptor cell differentiationGO:0060113290.109
cartilage developmentGO:0051216960.107
regulation of epithelial cell proliferationGO:005067830.107
regulation of signalingGO:00230512350.106
cation transmembrane transportGO:0098655650.103
regulation of cell differentiationGO:00455951420.102
aorta morphogenesisGO:003590930.101
regulation of signal transductionGO:00099662250.101
stem cell maintenanceGO:001982740.100
regulation of macromolecule metabolic processGO:00602553170.100
skeletal system developmentGO:00015011810.100
ear morphogenesisGO:0042471640.096
angiogenesisGO:00015251580.096
negative regulation of signal transductionGO:0009968940.095
macromolecule biosynthetic processGO:00090592270.094
branching morphogenesis of an epithelial tubeGO:0048754150.093
establishment of localizationGO:00512342440.093
Worm
locomotionGO:00400113130.093
Worm
tissue remodelingGO:004877140.092
glomerulus developmentGO:0032835270.090
kidney developmentGO:0001822920.090
neuron projection guidanceGO:0097485860.089
venous blood vessel developmentGO:006084190.087
regulation of cellular response to growth factor stimulusGO:0090287350.087
nephron epithelium morphogenesisGO:007208810.086
cell cycleGO:0007049930.085
sequestering of calcium ionGO:005120830.085
single organism localizationGO:19025782250.083
transportGO:00068102200.083
Worm
aorta developmentGO:003590440.081
diencephalon developmentGO:0021536580.079
endothelium developmentGO:0003158250.079
urogenital system developmentGO:0001655970.076
cilium organizationGO:0044782710.076
regulation of cell morphogenesis involved in differentiationGO:0010769380.076
sensory organ morphogenesisGO:00905962000.074
photoreceptor cell differentiationGO:0046530550.074
small molecule metabolic processGO:0044281770.071
liver developmentGO:0001889960.068
neuron recognitionGO:0008038180.068
adult behaviorGO:003053420.068
response to chemicalGO:00422213200.068
response to external stimulusGO:00096052640.067
anterior posterior pattern specificationGO:00099521520.067
mitotic nuclear divisionGO:0007067180.066
neuron projection extensionGO:1990138450.065
positive regulation of biological processGO:00485182530.065
gliogenesisGO:0042063450.064
regulation of biological qualityGO:00650082630.063
neuron projection morphogenesisGO:00488121610.062
organic acid metabolic processGO:0006082310.062
auditory receptor cell developmentGO:006011780.062
regulation of programmed cell deathGO:00430671010.062
rna modificationGO:000945120.061
segmentationGO:0035282970.061
regulation of cell deathGO:00109411030.060
cellular component biogenesisGO:00440851780.059
Zebrafish Worm
skeletal muscle tissue developmentGO:0007519670.059
Zebrafish
renal system developmentGO:0072001940.058
cellular response to growth factor stimulusGO:0071363390.058
ion transmembrane transportGO:0034220910.058
cation transportGO:0006812810.058
protein metabolic processGO:00195381830.057
developmental cell growthGO:0048588520.057
embryonic pattern specificationGO:0009880440.056
cellular response to chemical stimulusGO:00708871570.056
response to growth factorGO:0070848390.055
regulation of primary metabolic processGO:00800903110.055
meiotic chromosome segregationGO:004513230.055
negative regulation of protein kinase activityGO:000646940.054
negative regulation of response to stimulusGO:00485851040.052
programmed cell deathGO:00125011190.052
ion transportGO:00068111140.052
notch signaling pathwayGO:0007219350.052
transition metal ion transportGO:000004160.052
regulation of neuron differentiationGO:0045664560.052
regulation of smoothened signaling pathwayGO:0008589180.050
endothelial cell developmentGO:0001885120.050
carboxylic acid metabolic processGO:0019752220.050
regulation of developmental processGO:00507932470.050
taxisGO:00423301090.050
response to organic substanceGO:00100331530.049
protein complex subunit organizationGO:0071822460.048
Worm
cell differentiation in spinal cordGO:0021515400.048
cellular component assembly involved in morphogenesisGO:00109271070.048
Zebrafish Worm
mesenchyme developmentGO:00604851270.048
ribosomal small subunit biogenesisGO:004227420.048
eye morphogenesisGO:00485921440.046
cell motilityGO:00488702440.046
otolith developmentGO:0048840320.046
apoptotic processGO:00069151160.046
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.045
hindbrain developmentGO:0030902910.045
gastrulationGO:00073692080.045
organelle organizationGO:00069962270.045
Zebrafish Worm
protein localization to nucleusGO:003450430.045
regulation of cell projection organizationGO:0031344440.045
organic cyclic compound biosynthetic processGO:19013622230.045
gland developmentGO:00487321430.044
auditory receptor cell differentiationGO:0042491150.044
odontogenesis of dentin containing toothGO:004247510.044
morphogenesis of a branching epitheliumGO:0061138160.044
ameboidal type cell migrationGO:00016671430.043
negative regulation of apoptotic processGO:0043066550.043
negative regulation of signalingGO:0023057960.043
determination of left right symmetryGO:00073681790.043
sequestering of metal ionGO:005123830.043
deathGO:00162651210.042
nucleic acid metabolic processGO:00903042440.042
central nervous system neuron differentiationGO:0021953740.042
negative regulation of cell communicationGO:0010648960.041
nitrogen compound metabolic processGO:00068073190.041
cellular biosynthetic processGO:00442492860.041
blood circulationGO:0008015870.041
negative regulation of metabolic processGO:0009892860.041
ventral spinal cord developmentGO:0021517350.040
lipid storageGO:001991510.040
regulation of cellular metabolic processGO:00313233200.039
retina development in camera type eyeGO:00600411460.039
regulation of notch signaling pathwayGO:0008593160.039
nucleobase containing compound biosynthetic processGO:00346542050.038
positive regulation of cellular amine metabolic processGO:003324000.038
antimicrobial humoral responseGO:001973020.038
epithelial tube morphogenesisGO:00605621480.037
camera type eye morphogenesisGO:00485931080.037
amine metabolic processGO:000930820.037
mesenchymal cell developmentGO:0014031780.037
cellular protein catabolic processGO:004425740.036
regulation of axon extensionGO:0030516240.036
oxoacid metabolic processGO:0043436310.036
cell deathGO:00082191210.035
extracellular structure organizationGO:0043062270.035
venous endothelial cell migration involved in lymph vessel developmentGO:006085540.035
negative regulation of programmed cell deathGO:0043069580.035
nephron tubule morphogenesisGO:007207810.035
regulation of nucleocytoplasmic transportGO:004682220.035
heart contractionGO:0060047710.035
axon ensheathment in central nervous systemGO:003229120.034
negative regulation of kinase activityGO:003367340.034
double strand break repairGO:000630230.034
spinal cord developmentGO:0021510460.034
ventricular cardiac muscle tissue morphogenesisGO:005501020.034
neural tube patterningGO:0021532330.034
regulation of sequestering of calcium ionGO:005128240.034
neural tube developmentGO:0021915620.034
regulation of stem cell proliferationGO:007209120.033
b cell activationGO:004211320.033
single organism organelle organizationGO:19025891990.033
Zebrafish Worm
head morphogenesisGO:006032380.033
pigment cell differentiationGO:0050931380.033
myeloid cell homeostasisGO:0002262560.033
regulation of cell developmentGO:00602841000.032
melanocyte differentiationGO:0030318260.032
neural crest cell differentiationGO:0014033720.032
inorganic cation transmembrane transportGO:0098662500.032
histone deacetylationGO:001657520.032
agingGO:000756820.031
stem cell proliferationGO:007208940.031
regulation of multicellular organism growthGO:004001440.031
cellular ketone metabolic processGO:0042180110.031
positive regulation of signal transductionGO:0009967560.031
peripheral nervous system developmentGO:0007422550.031
developmental growthGO:00485891660.031
macromolecule modificationGO:00434121110.031
spinal cord motor neuron differentiationGO:0021522260.030
immune effector processGO:0002252230.029
multicellular organism growthGO:003526440.029
dorsal ventral pattern formationGO:00099531250.029
gene expressionGO:00104672520.029
cytoskeleton organizationGO:0007010960.029
Zebrafish Worm
ventricular cardiac muscle tissue developmentGO:000322930.029
positive regulation of cell cycleGO:004578730.028
somatic stem cell maintenanceGO:003501910.028
negative regulation of sequestering of calcium ionGO:005128340.028
regulation of apoptotic processGO:0042981980.028
cellular macromolecule metabolic processGO:00442603910.028
pericardium developmentGO:006003910.028
ventral spinal cord interneuron differentiationGO:0021514120.027
regulation of embryonic developmentGO:0045995470.027
chromosome organizationGO:0051276310.027
organelle localizationGO:0051640490.027
hypochord developmentGO:005501630.027
transmembrane transportGO:00550851200.027
protein import into nucleusGO:000660630.026
regulation of nervous system developmentGO:0051960900.026
glial cell migrationGO:000834730.026
positive regulation of neural precursor cell proliferationGO:200017910.026
regulation of localizationGO:00328791040.026
behaviorGO:0007610740.026
Worm
nuclear divisionGO:0000280230.026
regulation of bindingGO:005109830.026
cardiac atrium developmentGO:000323040.026
homeostatic processGO:00425921420.025
regulation of metabolic processGO:00192223590.025
semicircular canal developmentGO:0060872240.025
neural crest cell developmentGO:0014032620.025
determination of bilateral symmetryGO:00098552040.025
negative regulation of cell proliferationGO:000828580.025
extracellular matrix organizationGO:0030198270.025
cellular protein modification processGO:00064641000.025
central nervous system myelinationGO:002201020.025
synaptic vesicle recyclingGO:003646510.025
negative regulation of epithelial cell migrationGO:001063310.025
cellular response to extracellular stimulusGO:003166820.025
establishment of protein localization to organelleGO:007259440.025
epidermal cell fate specificationGO:000995740.024
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.024
chemotaxisGO:00069351040.024
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.024
cranial nerve developmentGO:0021545420.024
regulation of axonogenesisGO:0050770320.024
pronephros developmentGO:0048793690.024
negative regulation of cell deathGO:0060548600.024
positive regulation of cytosolic calcium ion concentrationGO:000720440.024
cellular component assemblyGO:00226071700.024
Zebrafish Worm
regulation of cell sizeGO:0008361290.024
neuronal action potentialGO:0019228180.024
wnt signaling pathway planar cell polarity pathwayGO:006007140.024
catecholamine metabolic processGO:000658420.024
face morphogenesisGO:006032560.024
negative regulation of protein phosphorylationGO:000193340.023
b cell differentiationGO:003018310.023
regulation of synaptic growth at neuromuscular junctionGO:000858210.023
rhombomere 5 developmentGO:002157140.023
regulation of cellular component organizationGO:0051128860.023
somite specificationGO:0001757120.023
regulation of vasculature developmentGO:1901342330.023
cellular aromatic compound metabolic processGO:00067252950.023
regulation of neural precursor cell proliferationGO:200017730.023
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.023
regulation of protein bindingGO:004339330.023
localization of cellGO:00516742440.022
fin developmentGO:0033333770.022
metal ion transportGO:0030001580.022
pancreas developmentGO:0031016840.022
regulation of meiotic cell cycleGO:005144510.022
negative regulation of cell differentiationGO:0045596460.022
negative regulation of cellular metabolic processGO:0031324770.022
epithelial to mesenchymal transitionGO:0001837210.022
single organism metabolic processGO:00447102170.022
multi organism processGO:00517041340.022
Worm
rna polyadenylationGO:004363120.022
regulation of cellular amine metabolic processGO:003323800.022
regulation of cytoplasmic transportGO:190364940.022
negative regulation of gliogenesisGO:001401410.022
biosynthetic processGO:00090582940.022
meiotic cell cycle processGO:190304630.021
convergent extension involved in gastrulationGO:0060027710.021
cell growthGO:0016049570.021
regulation of cell activationGO:005086510.021
regulation of extent of cell growthGO:0061387290.021
chemical homeostasisGO:0048878490.021
positive regulation of neuron apoptotic processGO:004352510.021
somitogenesisGO:0001756870.021
mrna polyadenylationGO:000637820.021
response to endogenous stimulusGO:0009719830.021
cell migrationGO:00164772370.021
type b pancreatic cell developmentGO:000332340.021
peripheral nervous system neuron differentiationGO:0048934280.021
peptide metabolic processGO:000651810.021
cellular amine metabolic processGO:004410620.021
developmental programmed cell deathGO:001062340.020
alpha amino acid metabolic processGO:190160530.020
establishment of localization in cellGO:0051649770.020
vasculogenesisGO:0001570410.020
regulation of mitotic cell cycleGO:0007346250.020
negative regulation of rna biosynthetic processGO:1902679450.020
embryonic heart tube morphogenesisGO:00031431080.020
single organism transportGO:00447652060.020
iron ion transportGO:000682640.020
tube closureGO:006060610.020
cellular response to external stimulusGO:007149620.020
cell recognitionGO:0008037190.020
negative regulation of endothelial cell migrationGO:001059610.020
wnt signaling pathwayGO:0016055800.019
smoothened signaling pathwayGO:0007224300.019
pectoral fin morphogenesisGO:0035138290.019
regulation of heart contractionGO:0008016320.019
cellular macromolecule biosynthetic processGO:00346452240.019
symbiosis encompassing mutualism through parasitismGO:004440340.019
nuclear transportGO:005116940.019
peptidyl tyrosine dephosphorylationGO:003533510.019
negative regulation of macromolecule metabolic processGO:0010605760.019
nucleocytoplasmic transportGO:000691340.018
left right pattern formationGO:0060972190.018
artery developmentGO:0060840220.018
cellular response to endogenous stimulusGO:0071495680.018
negative regulation of blood vessel endothelial cell migrationGO:004353710.018
regulation of establishment of protein localizationGO:007020140.018
regulation of reproductive processGO:200024140.018
skeletal muscle fiber developmentGO:0048741350.018
cardiac atrium morphogenesisGO:000320920.018
positive regulation of cell divisionGO:005178120.018
otolith morphogenesisGO:003247480.018
protein importGO:001703830.018
protein heterooligomerizationGO:005129110.018
nuclear importGO:005117030.017
lateral inhibitionGO:004633110.017
regulation of production of molecular mediator of immune responseGO:000270010.017
embryonic camera type eye developmentGO:0031076290.017
heart processGO:0003015710.017
endocardium morphogenesisGO:000316040.017
hepaticobiliary system developmentGO:0061008980.017
negative regulation of i kappab kinase nf kappab signalingGO:004312410.017
endothelial cell fate commitmentGO:006083930.017
response to fibroblast growth factorGO:0071774220.017
mitochondrion organizationGO:000700540.017
organic substance transportGO:0071702580.017
regulation of dendrite developmentGO:005077330.017
cellular nitrogen compound metabolic processGO:00346412900.017
homologous chromosome segregationGO:004514310.017
positive regulation of synapse assemblyGO:005196510.017
catechol containing compound metabolic processGO:000971220.017
foregut morphogenesisGO:000744040.017
regulation of autophagyGO:001050630.017
heterocycle metabolic processGO:00464832900.016
face developmentGO:006032480.016
proteasomal protein catabolic processGO:001049820.016
single organism nuclear importGO:190259330.016
regulation of neurotransmitter transportGO:005158810.016
cell projection assemblyGO:0030031640.016
nephron morphogenesisGO:007202820.016
regulation of organelle organizationGO:0033043290.016
regulation of organ growthGO:004662030.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
regulation of cellular ketone metabolic processGO:001056570.016
calcium ion transport into cytosolGO:006040230.016
pectoral fin developmentGO:0033339500.016
collagen fibril organizationGO:003019910.016
chondrocyte intercalation involved in growth plate cartilage morphogenesisGO:000342810.016
negative regulation of neuron differentiationGO:0045665100.016
regulation of blood pressureGO:000821710.016
peptidyl serine phosphorylationGO:001810510.016
blood vessel endothelial cell proliferation involved in sprouting angiogenesisGO:000204340.016
multicellular organismal signalingGO:0035637220.016
determination of pancreatic left right asymmetryGO:0035469110.016
mesenchymal cell proliferationGO:001046310.015
embryonic neurocranium morphogenesisGO:0048702150.015
embryonic digestive tract developmentGO:004856640.015
cellular response to starvationGO:000926710.015
morphogenesis of follicular epitheliumGO:001633310.015
nuclear exportGO:005116810.015
cell substrate junction assemblyGO:000704420.015
cellular protein metabolic processGO:00442671290.015
regulation of neurotransmitter secretionGO:004692810.015
response to transition metal nanoparticleGO:1990267280.015
peptidyl lysine acetylationGO:001839420.015
regulation of wnt signaling pathwayGO:0030111530.015
erythrocyte differentiationGO:0030218540.015
mitotic cell cycleGO:0000278640.015
cellular nitrogen compound biosynthetic processGO:00442712180.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.015
production of molecular mediator of immune responseGO:000244020.015
muscle tissue developmentGO:00605371100.015
Zebrafish
regulation of stem cell differentiationGO:200073640.015
rna biosynthetic processGO:00327741810.015
regulation of protein import into nucleusGO:004230620.015
muscle fiber developmentGO:0048747520.015
synaptic vesicle localizationGO:009747910.015
vestibular receptor cell differentiationGO:006011430.015
cellular response to nutrient levelsGO:003166920.015
somatic muscle developmentGO:000752540.015
cartilage morphogenesisGO:0060536130.015
neural crest cell migrationGO:0001755420.015
myeloid cell differentiationGO:0030099860.015
positive regulation of immune effector processGO:000269930.015
lymph vessel developmentGO:0001945270.014
nucleobase containing compound metabolic processGO:00061392740.014
cell type specific apoptotic processGO:0097285220.014
meiosis iGO:000712710.014
notochord cell differentiationGO:0060034180.014
regulation of retina development in camera type eyeGO:190286620.014
growthGO:00400071740.014
system processGO:00030081850.014
endothelial cell proliferationGO:0001935110.014
regulation of nucleoside metabolic processGO:000911820.014
sister chromatid cohesionGO:000706220.014
protein targeting to nucleusGO:004474430.014
glial cell differentiationGO:0010001420.014
sprouting angiogenesisGO:0002040530.014
cellular amino acid metabolic processGO:000652070.014
regulation of macromolecule biosynthetic processGO:00105562250.013
primary neural tube formationGO:001402010.013
leukocyte activationGO:0045321120.013
central nervous system myelin formationGO:003228910.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
negative regulation of cell developmentGO:0010721260.013
embryonic retina morphogenesis in camera type eyeGO:0060059220.013
negative regulation of nucleobase containing compound metabolic processGO:0045934590.013
eye photoreceptor cell differentiationGO:0001754450.013
muscle structure developmentGO:00610611960.013
Zebrafish Worm
positive regulation of jnk cascadeGO:004633030.013
heparan sulfate proteoglycan metabolic processGO:003020160.013
morphogenesis of an epithelial sheetGO:0002011490.013
positive regulation of cellular processGO:00485222010.013
heart loopingGO:0001947940.013

unc45a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.041
disease of cellular proliferationDOID:1456600.041
endocrine gland cancerDOID:17000.038
organ system cancerDOID:005068600.038
disease of anatomical entityDOID:700.024
cardiovascular system diseaseDOID:128700.024
gastrointestinal system cancerDOID:311900.013