Danio rerio

46 known processes

unc45b

unc-45 homolog B (C. elegans)

(Aliases: wu:fa10f03,wu:fb96f06,wu:fa05a03,wu:fb37f02,wu:fc10f04,cb393,unc45r)

unc45b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
muscle structure developmentGO:00610611960.999
striated muscle cell differentiationGO:00511461290.998
myofibril assemblyGO:0030239480.994
skeletal muscle organ developmentGO:0060538780.994
muscle cell differentiationGO:00426921390.989
muscle organ developmentGO:00075171010.988
muscle cell developmentGO:00550011150.987
skeletal myofibril assemblyGO:001486670.985
cellular component morphogenesisGO:00329893360.983
striated muscle cell developmentGO:00550021080.972
single organism organelle organizationGO:19025891990.967
actomyosin structure organizationGO:0031032530.965
skeletal muscle tissue developmentGO:0007519670.951
organelle assemblyGO:00709251100.946
sarcomere organizationGO:0045214260.939
Worm
myosin filament assemblyGO:003103460.937
Worm
cellular component assembly involved in morphogenesisGO:00109271070.926
skeletal muscle thin filament assemblyGO:003024040.922
regulation of multicellular organismal processGO:00512392770.909
organelle organizationGO:00069962270.897
heart morphogenesisGO:00030071560.896
muscle system processGO:0003012200.884
myosin filament organizationGO:003103360.881
Worm
heart developmentGO:00075073130.879
cardiac muscle cell differentiationGO:0055007300.878
neuron differentiationGO:00301823530.869
chordate embryonic developmentGO:00430092710.863
cytoskeleton organizationGO:0007010960.861
embryo development ending in birth or egg hatchingGO:00097922710.853
Worm
regulation of muscle contractionGO:000693730.810
skeletal muscle fiber developmentGO:0048741350.800
blood circulationGO:0008015870.790
Zebrafish
cell projection organizationGO:00300302840.773
muscle tissue developmentGO:00605371100.764
regulation of sarcomere organizationGO:006029720.762
sarcomerogenesisGO:004876940.730
muscle fiber developmentGO:0048747520.716
skeletal muscle myosin thick filament assemblyGO:003024150.716
generation of neuronsGO:00486993850.680
system processGO:00030081850.675
Zebrafish
regulation of cell differentiationGO:00455951420.670
notochord developmentGO:0030903540.662
cell morphogenesis involved in neuron differentiationGO:00486671630.641
cellular component assemblyGO:00226071700.630
striated muscle myosin thick filament assemblyGO:007168860.625
Worm
regulation of system processGO:0044057400.613
cell morphogenesis involved in differentiationGO:00009041950.609
striated muscle tissue developmentGO:00147061100.607
cell morphogenesisGO:00009022890.577
embryonic skeletal system morphogenesisGO:0048704930.561
segmentationGO:0035282970.556
neuron developmentGO:00486662620.556
larval behaviorGO:003053750.531
muscle contractionGO:0006936180.527
circadian sleep wake cycleGO:004274520.526
skeletal system developmentGO:00015011810.522
Zebrafish
circadian sleep wake cycle sleepGO:005080210.519
neuron projection developmentGO:00311751800.512
regulation of cell developmentGO:00602841000.484
heart processGO:0003015710.482
axonal fasciculationGO:0007413110.476
ventricular cardiac muscle tissue morphogenesisGO:005501020.464
circulatory system processGO:0003013870.452
Zebrafish
embryonic skeletal system developmentGO:0048706970.451
circadian sleep wake cycle processGO:002241020.451
regulation of metabolic processGO:00192223590.448
regulation of anatomical structure morphogenesisGO:00226031300.439
heart contractionGO:0060047710.430
actin filament based processGO:0030029640.420
blood vessel developmentGO:00015682460.412
Zebrafish
somatic muscle developmentGO:000752540.410
regulation of blood circulationGO:1903522320.410
larval developmentGO:000216420.407
locomotionGO:00400113130.396
Worm
central nervous system developmentGO:00074173870.385
positive regulation of skeletal muscle tissue developmentGO:004864310.376
somite developmentGO:0061053960.356
somite specificationGO:0001757120.349
regulation of synapse assemblyGO:005196330.346
cellular component biogenesisGO:00440851780.330
embryonic viscerocranium morphogenesisGO:0048703520.330
sleepGO:003043110.327
embryonic organ morphogenesisGO:00485622740.324
regulation of stem cell proliferationGO:007209120.321
positive regulation of blood circulationGO:190352420.316
embryonic pattern specificationGO:0009880440.315
cardiac muscle fiber developmentGO:004873930.312
somitogenesisGO:0001756870.308
embryonic cranial skeleton morphogenesisGO:0048701900.299
embryonic organ developmentGO:00485683810.292
establishment of localizationGO:00512342440.292
Worm
actin cytoskeleton organizationGO:0030036630.276
musculoskeletal movementGO:005088180.272
heterocycle metabolic processGO:00464832900.272
cell motilityGO:00488702440.272
cell projection morphogenesisGO:00488582440.267
regulation of biological qualityGO:00650082630.261
regulation of cell projection assemblyGO:006049140.259
cardiac muscle myosin thick filament assemblyGO:007169010.251
muscle cell migrationGO:001481240.242
behaviorGO:0007610740.242
Worm
skeletal muscle contractionGO:000300950.241
myotube differentiationGO:0014902450.233
cellular biosynthetic processGO:00442492860.228
regulation of striated muscle contractionGO:000694220.225
localization of cellGO:00516742440.223
skeletal system morphogenesisGO:00487051020.213
nitrogen compound metabolic processGO:00068073190.213
sensory organ developmentGO:00074233930.211
axonogenesisGO:00074091520.203
cardiac atrium morphogenesisGO:000320920.201
neuromuscular synaptic transmissionGO:000727420.201
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217520.200
purine nucleoside monophosphate catabolic processGO:000912840.192
regulation of response to stimulusGO:00485832690.191
cardiac muscle cell developmentGO:0055013200.186
ventricular cardiac muscle tissue developmentGO:000322930.184
cardiocyte differentiationGO:0035051440.184
digestive tract developmentGO:00485652650.184
taxisGO:00423301090.178
regulation of nervous system developmentGO:0051960900.174
protein localization to nucleusGO:003450430.173
positive regulation of heart contractionGO:004582320.170
single organism localizationGO:19025782250.165
cardiac muscle tissue morphogenesisGO:005500870.164
anterior posterior pattern specificationGO:00099521520.159
response to salt stressGO:0009651100.157
cardiac chamber morphogenesisGO:0003206120.156
cell cycleGO:0007049930.154
positive regulation of transportGO:005105020.152
cell projection assemblyGO:0030031640.151
transmembrane transportGO:00550851200.149
morphogenesis of an epitheliumGO:00020093330.149
muscle organ morphogenesisGO:004864480.143
adult behaviorGO:003053420.140
macromolecular complex subunit organizationGO:0043933740.140
Worm
regulation of skeletal muscle fiber developmentGO:004874220.139
cellular macromolecule metabolic processGO:00442603910.137
stem cell proliferationGO:007208940.133
axon guidanceGO:0007411860.131
organic substance biosynthetic processGO:19015762890.131
cardiac ventricle formationGO:000321110.130
digestive system developmentGO:00551232890.130
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.129
cation homeostasisGO:0055080330.129
regulation of myotube differentiationGO:001083020.128
macromolecule biosynthetic processGO:00090592270.128
embryonic heart tube developmentGO:00350501330.128
protein import into nucleusGO:000660630.127
regulation of cell projection organizationGO:0031344440.126
establishment of protein localization to organelleGO:007259440.126
single organism metabolic processGO:00447102170.125
homeostatic processGO:00425921420.124
outflow tract morphogenesisGO:000315110.121
regulation of cardiac muscle contractionGO:005511720.120
neuron recognitionGO:0008038180.120
regulation of synapse organizationGO:005080730.119
myotube cell developmentGO:0014904350.119
atp catabolic processGO:000620040.115
regulation of cellular component organizationGO:0051128860.115
regulation of neural precursor cell proliferationGO:200017730.115
positive regulation of biological processGO:00485182530.111
determination of left right symmetryGO:00073681790.111
regulation of synaptic growth at neuromuscular junctionGO:000858210.110
nucleoside monophosphate catabolic processGO:000912540.109
regulation of cellular metabolic processGO:00313233200.109
regulation of multicellular organismal developmentGO:20000262230.109
regulation of cellular biosynthetic processGO:00313262450.108
heart loopingGO:0001947940.108
response to chemicalGO:00422213200.107
regulation of skeletal muscle tissue developmentGO:004864140.105
actin filament organizationGO:0007015150.105
regulation of nucleoside metabolic processGO:000911820.105
cellular protein catabolic processGO:004425740.104
neurotransmitter secretionGO:000726920.102
organonitrogen compound metabolic processGO:1901564740.100
cellular aromatic compound metabolic processGO:00067252950.099
response to stressGO:00069502630.098
cilium organizationGO:0044782710.097
regulation of cellular amine metabolic processGO:003323800.097
positive regulation of cytosolic calcium ion concentrationGO:000720440.096
cognitionGO:005089010.094
gene expressionGO:00104672520.092
regulation of primary metabolic processGO:00800903110.091
cell part morphogenesisGO:00329902460.090
transportGO:00068102200.090
Worm
lipid storageGO:001991510.088
detection of mechanical stimulus involved in sensory perception of touchGO:005097620.088
regulation of cell communicationGO:00106462320.088
neuron projection morphogenesisGO:00488121610.088
nuclear importGO:005117030.088
rna localizationGO:000640340.087
locomotory behaviorGO:0007626340.086
regionalizationGO:00030022740.086
single organism cellular localizationGO:1902580460.085
response to endogenous stimulusGO:0009719830.084
regulation of behaviorGO:0050795240.084
embryonic heart tube morphogenesisGO:00031431080.081
protein importGO:001703830.081
regulation of developmental processGO:00507932470.081
cardiac chamber formationGO:000320740.081
determination of bilateral symmetryGO:00098552040.080
neuron projection guidanceGO:0097485860.079
brain developmentGO:00074202930.078
regulation of transmembrane transporter activityGO:002289820.077
cell migrationGO:00164772370.077
extraocular skeletal muscle developmentGO:000207430.076
motor neuron axon guidanceGO:0008045230.076
tube morphogenesisGO:00352393490.076
regulation of macromolecule metabolic processGO:00602553170.076
chemical homeostasisGO:0048878490.075
nitric oxide biosynthetic processGO:000680920.075
reactive nitrogen species metabolic processGO:200105700.075
epithelial cell differentiationGO:00308551160.075
extracellular structure organizationGO:0043062270.074
axoneme assemblyGO:003508290.072
nuclear transportGO:005116940.072
muscle cell fate determinationGO:000752110.070
calcium ion homeostasisGO:0055074190.069
regulation of catalytic activityGO:0050790550.068
venous blood vessel morphogenesisGO:004884530.068
cellular amino acid metabolic processGO:000652070.068
axon developmentGO:00615641660.068
chemotaxisGO:00069351040.068
cytosolic calcium ion transportGO:006040130.067
cellular component movementGO:00069283350.067
membrane repolarizationGO:008600920.066
regulation of organelle assemblyGO:190211540.065
heart valve formationGO:000318840.065
cell cell signalingGO:0007267520.064
regulation of heart contractionGO:0008016320.064
calcium ion transport into cytosolGO:006040230.063
regulation of skeletal muscle cell differentiationGO:200101410.063
nucleocytoplasmic transportGO:000691340.062
cellular macromolecule biosynthetic processGO:00346452240.061
nucleobase containing compound metabolic processGO:00061392740.061
single organism nuclear importGO:190259330.061
cellular amino acid biosynthetic processGO:000865220.060
cilium assemblyGO:0042384580.059
multicellular organismal movementGO:005087980.059
epithelial tube morphogenesisGO:00605621480.058
amine metabolic processGO:000930820.057
purine ribonucleoside monophosphate catabolic processGO:000916940.056
cellular protein localizationGO:0034613200.056
regulation of nitric oxide mediated signal transductionGO:001074910.055
regulation of circadian sleep wake cycle sleepGO:004518710.055
basement membrane assemblyGO:007083130.055
regulation of neurogenesisGO:0050767870.054
mesenchyme developmentGO:00604851270.054
endocardial cushion morphogenesisGO:000320330.054
cardiac muscle tissue developmentGO:0048738480.054
regulation of rna metabolic processGO:00512522240.053
meiotic nuclear divisionGO:000712640.053
positive regulation of cellular processGO:00485222010.053
heart valve developmentGO:0003170140.053
regulation of ion transmembrane transporter activityGO:003241220.052
positive regulation of stem cell proliferationGO:200064810.052
maintenance of locationGO:005123540.052
regulation of n methyl d aspartate selective glutamate receptor activityGO:200031010.051
inositol lipid mediated signalingGO:004801720.051
regulation of nitrogen compound metabolic processGO:00511712510.051
cellular macromolecule localizationGO:0070727210.050
spermatid differentiationGO:004851520.049
signal transductionGO:00071654550.049
voluntary skeletal muscle contractionGO:000301040.049
post embryonic morphogenesisGO:000988640.049
regulation of cytoplasmic transportGO:190364940.049
positive regulation of cell cycleGO:004578730.048
vasculature developmentGO:00019442780.048
Zebrafish
striated muscle contractionGO:0006941120.048
positive regulation of cellular component biogenesisGO:004408930.048
regulation of transporter activityGO:003240920.047
developmental growthGO:00485891660.046
cell death in response to oxidative stressGO:003647320.046
regulation of cell proliferation involved in heart morphogenesisGO:200013620.046
response to lipidGO:0033993600.046
response to woundingGO:00096111160.046
cardiac ventricle developmentGO:000323190.045
synaptic growth at neuromuscular junctionGO:005112420.044
macromolecule modificationGO:00434121110.044
3 utr mediated mrna stabilizationGO:007093530.044
protein metabolic processGO:00195381830.044
cellular nitrogen compound biosynthetic processGO:00442712180.044
specification of symmetryGO:00097992040.044
ear developmentGO:00435831270.043
regulation of extent of cell growthGO:0061387290.043
small molecule metabolic processGO:0044281770.042
cardiac chamber developmentGO:0003205190.042
agingGO:000756820.042
positive regulation of neural precursor cell proliferationGO:200017910.041
ion transmembrane transportGO:0034220910.041
cellular response to vascular endothelial growth factor stimulusGO:003592430.041
cellular nitrogen compound metabolic processGO:00346412900.041
lymphoid lineage cell migration into thymusGO:009753540.041
regulation of synapse structure and activityGO:005080350.041
single organism cell adhesionGO:0098602290.040
regulation of dendrite developmentGO:005077330.040
endocardial cushion formationGO:000327220.040
nucleic acid templated transcriptionGO:00976591810.039
heart rudiment morphogenesisGO:000331460.039
regulation of cellular component sizeGO:0032535300.038
mesenchymal cell developmentGO:0014031780.038
pharyngeal muscle developmentGO:004328240.038
response to abiotic stimulusGO:00096281220.038
myoblast fusionGO:0007520100.038
regulation of developmental growthGO:0048638380.038
spermatid developmentGO:000728620.038
negative regulation of cellular processGO:00485232830.038
regulation of axonogenesisGO:0050770320.038
protein localizationGO:0008104400.037
macromolecule localizationGO:0033036540.037
cellular response to fluid shear stressGO:007149810.037
cellular ion homeostasisGO:0006873170.037
determination of heart left right asymmetryGO:00613711170.037
negative regulation of biological processGO:00485193040.037
cellular response to hormone stimulusGO:0032870390.036
female gamete generationGO:0007292140.036
eye developmentGO:00016542770.036
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.036
heart joggingGO:0003146400.036
positive regulation of muscle cell differentiationGO:005114910.036
lymphoid lineage cell migrationGO:009753440.036
connective tissue developmentGO:0061448990.036
Zebrafish
neurotransmitter transportGO:000683620.036
regulation of circadian rhythmGO:004275240.035
intracellular signal transductionGO:0035556850.035
ion transportGO:00068111140.035
chondrocyte intercalation involved in growth plate cartilage morphogenesisGO:000342810.035
mitochondrion organizationGO:000700540.034
protein stabilizationGO:005082120.034
regulation of transportGO:0051049450.034
ribonucleoside monophosphate catabolic processGO:000915840.034
response to external stimulusGO:00096052640.034
cardiac myofibril assemblyGO:005500390.033
muscle tissue morphogenesisGO:006041570.033
cell surface receptor signaling pathwayGO:00071663250.033
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.033
myotome developmentGO:006105510.032
cell recognitionGO:0008037190.032
neuron projection regenerationGO:0031102160.031
lens fiber cell morphogenesisGO:007030930.031
pharynx developmentGO:006046550.031
vasculogenesisGO:0001570410.031
regulation of protein targetingGO:190353320.030
cellular protein metabolic processGO:00442671290.030
regulation of locomotionGO:0040012550.030
regulation of apoptotic processGO:0042981980.030
protein targeting to nucleusGO:004474430.030
regulation of cytokine productionGO:000181730.030
synaptic transmission cholinergicGO:000727140.030
endocardium formationGO:006021410.030
regulation of protein import into nucleusGO:004230620.030
regulation of tube sizeGO:003515020.030
neural crest cell differentiationGO:0014033720.029
regulation of axon extensionGO:0030516240.029
response to organic substanceGO:00100331530.029
cardiac atrium developmentGO:000323040.029
intracellular transportGO:0046907320.029
nucleic acid metabolic processGO:00903042440.029
venous blood vessel developmentGO:006084190.029
protein localization to membraneGO:007265790.029
directional locomotionGO:003305810.028
growthGO:00400071740.028
anatomical structure homeostasisGO:0060249360.028
cell proliferation involved in heart morphogenesisGO:006132320.028
heart field specificationGO:000312810.028
larval locomotory behaviorGO:000834550.028
single organism intracellular transportGO:1902582250.028
nucleoside phosphate metabolic processGO:0006753280.028
regulation of growthGO:0040008420.027
biosynthetic processGO:00090582940.027
nephron tubule epithelial cell differentiationGO:007216010.027
regulation of intracellular protein transportGO:003315730.027
response to mercury ionGO:004668910.027
cilium morphogenesisGO:0060271850.027
regulation of phosphorus metabolic processGO:0051174430.027
mrna transportGO:005102820.026
nucleic acid transportGO:005065720.026
microtubule organizing center organizationGO:003102310.026
regulation of purine nucleotide catabolic processGO:003312120.026
regulation of glutamate receptor signaling pathwayGO:190044910.026
cardiac muscle contractionGO:006004860.026
neuron migrationGO:0001764220.026
regulation of rna biosynthetic processGO:20011412130.026
nitric oxide metabolic processGO:004620920.026
mesenchymal cell differentiationGO:0048762870.026
regulation of mechanoreceptor differentiationGO:004563110.025
positive regulation of muscle organ developmentGO:004863610.025
regulation of syncytium formation by plasma membrane fusionGO:006014220.025
cellular calcium ion homeostasisGO:0006874130.025
slow twitch skeletal muscle fiber contractionGO:003144430.025
modification dependent macromolecule catabolic processGO:004363230.025
camera type eye developmentGO:00430102220.025
neural tube patterningGO:0021532330.025
regulation of biosynthetic processGO:00098892500.025
cellular response to chemical stimulusGO:00708871570.025
atrial ventricular junction remodelingGO:000329420.025
regulation of dna templated transcription elongationGO:003278430.025
cellular localizationGO:0051641970.025
sodium ion transportGO:0006814240.024
ion homeostasisGO:0050801410.024
regulation of signal transductionGO:00099662250.024
cardiac ventricle morphogenesisGO:000320870.024
regulation of protein transportGO:005122330.024
regulation of blood pressureGO:000821710.024
fin developmentGO:0033333770.024
inner ear developmentGO:00488391260.023
organic acid metabolic processGO:0006082310.023
cation transmembrane transportGO:0098655650.023
rna transportGO:005065820.023
photoreceptor cell fate commitmentGO:004655210.023
single organism transportGO:00447652060.023
body morphogenesisGO:0010171160.023
Worm
single organism reproductive processGO:0044702400.023
single organism behaviorGO:0044708240.023
tissue remodelingGO:004877140.023
regulation of blood vessel sizeGO:005088020.022
regulation of protein bindingGO:004339330.022
renal system developmentGO:0072001940.022
forebrain midbrain boundary formationGO:002190510.022
protein modification processGO:00362111000.022
optic nerve developmentGO:0021554150.022
positive regulation of striated muscle tissue developmentGO:004584410.021
branching morphogenesis of a nerveGO:004875540.021
cell matrix adhesionGO:000716040.021
wound healingGO:0042060900.021
platelet formationGO:003022010.020
head developmentGO:00603223030.020
rna metabolic processGO:00160702190.020
multicellular organismal reproductive processGO:0048609350.020
Worm
glial cell migrationGO:000834730.020
rostrocaudal neural tube patterningGO:0021903290.020
regulation of heart growthGO:006042020.020
regulation of mitotic cell cycle embryonicGO:000979420.020
heterocycle biosynthetic processGO:00181302150.020
lamellipodium organizationGO:009758110.019
regulation of cell morphogenesisGO:0022604420.019
lamellipodium assemblyGO:003003210.019
ventricular cardiac myofibril assemblyGO:005500540.019
catabolic processGO:0009056320.019
fertilizationGO:000956630.019
segment specificationGO:0007379120.019
cardiac cell developmentGO:0055006210.019
cytoskeleton dependent cytokinesisGO:006164030.019
response to growth factorGO:0070848390.019
sensory system developmentGO:0048880760.018
lateral line developmentGO:0048882660.018
cell cycle arrestGO:000705010.018
cellular response to toxic substanceGO:009723710.018
multicellular organism reproductionGO:0032504350.018
Worm
mesoderm developmentGO:0007498880.018
modification dependent protein catabolic processGO:001994130.018
dendrite developmentGO:001635890.018
endoplasmic reticulum unfolded protein responseGO:003096820.017
dorsal aorta morphogenesisGO:003591230.017
response to organonitrogen compoundGO:0010243120.017
divalent inorganic cation homeostasisGO:0072507220.017
artery developmentGO:0060840220.017
enzyme linked receptor protein signaling pathwayGO:00071671060.017
response to steroid hormoneGO:0048545350.017
ubiquitin dependent protein catabolic processGO:000651130.017
notochord morphogenesisGO:0048570170.017
positive regulation of nervous system developmentGO:0051962250.017
cellular response to organic cyclic compoundGO:0071407380.017
skin developmentGO:0043588540.017
negative regulation of striated muscle tissue developmentGO:004584320.017
developmental maturationGO:0021700340.016
establishment of localization in cellGO:0051649770.016
camera type eye morphogenesisGO:00485931080.016
blood vessel endothelial cell differentiationGO:006083720.016
reproductionGO:0000003400.016
Worm
phosphorus metabolic processGO:00067931090.016
atrial cardiac myofibril assemblyGO:005500420.016
epithelial cell developmentGO:0002064420.016
cartilage developmentGO:0051216960.016
Zebrafish
cellular aldehyde metabolic processGO:000608140.016
cation transportGO:0006812810.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016

unc45b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
muscle tissue diseaseDOID:6600.596
musculoskeletal system diseaseDOID:1700.596
myopathyDOID:42300.596
muscular diseaseDOID:008000000.596
disease of anatomical entityDOID:700.596
intrinsic cardiomyopathyDOID:006003600.214
heart diseaseDOID:11400.214
cardiovascular system diseaseDOID:128700.214
cardiomyopathyDOID:005070000.214
hypertrophic cardiomyopathyDOID:1198400.051
muscular dystrophyDOID:988400.021
limb girdle muscular dystrophyDOID:1172400.021
neuromuscular diseaseDOID:44000.017
neuropathyDOID:87000.017
charcot marie tooth diseaseDOID:1059500.017
charcot marie tooth disease type 2DOID:005053900.017
nervous system diseaseDOID:86300.017