IMP: Integrative Multi-species Prediction

Danio rerio

0 known processes

dvr1

decapentaplegic and Vg-related 1

(Aliases: cb556,zDVR1,zDVR-1,VG1,zgc:103542,DVR-1)

Entrez: 30125
ZFIN: ZDB-GENE-980526-389
Ensembl: ENSDARG00000037995
UniProtKB: P35621

Process Predictions
Disease Predictions

dvr1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
organic substance biosynthetic process	GO:1901576	289	0.206	Zebrafish Fly
cellular nitrogen compound metabolic process	GO:0034641	290	0.201	Zebrafish Fly
oocyte maturation	GO:0001556	4	0.178
nucleic acid metabolic process	GO:0090304	244	0.172	Zebrafish Fly
regulation of multicellular organismal process	GO:0051239	277	0.169	Human Zebrafish Mouse Fly
specification of symmetry	GO:0009799	204	0.149	Zebrafish
heterocycle metabolic process	GO:0046483	290	0.145	Zebrafish Fly
regulation of metabolic process	GO:0019222	359	0.141	Human Zebrafish Fly
regulation of cellular biosynthetic process	GO:0031326	245	0.141	Human Zebrafish Fly
regulation of cellular metabolic process	GO:0031323	320	0.136	Human Zebrafish Fly
rna metabolic process	GO:0016070	219	0.129	Zebrafish Fly
response to external stimulus	GO:0009605	264	0.129	Mouse Fly
negative regulation of cellular process	GO:0048523	283	0.124	Human Zebrafish Mouse Fly
regulation of developmental process	GO:0050793	247	0.121	Human Zebrafish Mouse Fly
determination of left right symmetry	GO:0007368	179	0.121	Zebrafish
cellular aromatic compound metabolic process	GO:0006725	295	0.117	Zebrafish Fly
regulation of nucleic acid templated transcription	GO:1903506	213	0.115	Human Zebrafish Fly
oocyte development	GO:0048599	14	0.114	Fly
organic cyclic compound metabolic process	GO:1901360	301	0.109	Zebrafish Fly
cellular macromolecule metabolic process	GO:0044260	391	0.105	Zebrafish Fly
regulation of reproductive process	GO:2000241	4	0.104
regulation of primary metabolic process	GO:0080090	311	0.102	Human Zebrafish Fly
striated muscle cell differentiation	GO:0051146	129	0.101	Zebrafish Mouse
skeletal muscle organ development	GO:0060538	78	0.098	Mouse
regulation of macromolecule biosynthetic process	GO:0010556	225	0.096	Human Zebrafish Fly
signal transduction	GO:0007165	455	0.092	Human Zebrafish Mouse Fly
cellular biosynthetic process	GO:0044249	286	0.091	Zebrafish Fly
striated muscle tissue development	GO:0014706	110	0.085	Zebrafish Mouse
aromatic compound biosynthetic process	GO:0019438	217	0.085	Zebrafish Fly
single organism metabolic process	GO:0044710	217	0.085
neuron development	GO:0048666	262	0.076
regulation of nitrogen compound metabolic process	GO:0051171	251	0.074	Human Zebrafish Fly
digestive tract morphogenesis	GO:0048546	231	0.074	Zebrafish Mouse Fly
regulation of oocyte development	GO:0060281	3	0.070
chordate embryonic development	GO:0043009	271	0.070	Mouse
response to nutrient	GO:0007584	3	0.069
regulation of transcription dna templated	GO:0006355	213	0.067	Human Zebrafish Fly
regulation of nucleobase containing compound metabolic process	GO:0019219	250	0.066	Human Zebrafish Fly
heterocycle biosynthetic process	GO:0018130	215	0.066	Zebrafish Fly
maintenance of location	GO:0051235	4	0.065
rna biosynthetic process	GO:0032774	181	0.062	Zebrafish Fly
nucleobase containing compound metabolic process	GO:0006139	274	0.062	Zebrafish Fly
single fertilization	GO:0007338	3	0.060
regulation of rna biosynthetic process	GO:2001141	213	0.059	Human Zebrafish Fly
determination of bilateral symmetry	GO:0009855	204	0.057	Zebrafish
heart morphogenesis	GO:0003007	156	0.056	Zebrafish
cellular component biogenesis	GO:0044085	178	0.056	Zebrafish
heart development	GO:0007507	313	0.055	Zebrafish Fly
tube morphogenesis	GO:0035239	349	0.054	Zebrafish Mouse Fly
gene expression	GO:0010467	252	0.054	Zebrafish Fly
cellular macromolecule biosynthetic process	GO:0034645	224	0.053	Zebrafish Fly
multi organism process	GO:0051704	134	0.052	Fly
positive regulation of cellular catabolic process	GO:0031331	3	0.052
nitrogen compound metabolic process	GO:0006807	319	0.051	Zebrafish Fly
blood vessel development	GO:0001568	246	0.049
positive regulation of cellular metabolic process	GO:0031325	94	0.048
response to chemical	GO:0042221	320	0.048	Fly
response to monosaccharide	GO:0034284	3	0.047
positive regulation of cell cycle	GO:0045787	3	0.047
embryo development ending in birth or egg hatching	GO:0009792	271	0.046	Mouse Fly
regulation of signaling	GO:0023051	235	0.046	Human
positive regulation of nucleobase containing compound metabolic process	GO:0045935	69	0.044
negative regulation of biological process	GO:0048519	304	0.043	Human Zebrafish Mouse Fly
meiotic cell cycle process	GO:1903046	3	0.043
muscle tissue development	GO:0060537	110	0.043	Zebrafish Mouse
vasculature development	GO:0001944	278	0.042
regulation of gene expression	GO:0010468	265	0.042	Human Zebrafish Fly
digestive tract development	GO:0048565	265	0.042	Zebrafish Mouse Fly
lipid storage	GO:0019915	1	0.042
regulation of response to stimulus	GO:0048583	269	0.042	Human
myotube cell development	GO:0014904	35	0.041	Mouse
nucleobase containing compound biosynthetic process	GO:0034654	205	0.041	Zebrafish Fly
larval development	GO:0002164	2	0.040	Fly
angiogenesis	GO:0001525	158	0.040
organonitrogen compound metabolic process	GO:1901564	74	0.039
regulation of biosynthetic process	GO:0009889	250	0.039	Human Zebrafish Fly
digestive system development	GO:0055123	289	0.038	Zebrafish Mouse Fly
maternal determination of anterior posterior axis embryo	GO:0008358	4	0.037
cell cell recognition	GO:0009988	1	0.037
positive regulation of reproductive process	GO:2000243	2	0.037
pole plasm assembly	GO:0007315	4	0.036
regulation of protein complex assembly	GO:0043254	3	0.036
negative regulation of macromolecule metabolic process	GO:0010605	76	0.036	Fly
positive regulation of biological process	GO:0048518	253	0.036	Zebrafish Fly
regulation of cell communication	GO:0010646	232	0.036	Human
cellular nitrogen compound biosynthetic process	GO:0044271	218	0.035	Zebrafish Fly
biosynthetic process	GO:0009058	294	0.035	Zebrafish Fly
positive regulation of cellular process	GO:0048522	201	0.035	Zebrafish
muscle fiber development	GO:0048747	52	0.035	Mouse
regulation of endodermal cell fate specification	GO:0042663	15	0.035	Zebrafish
cellular component assembly	GO:0022607	170	0.034	Zebrafish
locomotion	GO:0040011	313	0.034	Zebrafish Fly
morphogenesis of an epithelium	GO:0002009	333	0.034	Zebrafish Fly
positive regulation of metabolic process	GO:0009893	108	0.034
determination of ventral identity	GO:0048264	21	0.034	Zebrafish
mitochondrion organization	GO:0007005	4	0.033
oocyte anterior posterior axis specification	GO:0007314	4	0.033
regulation of alternative mrna splicing via spliceosome	GO:0000381	1	0.032
heart looping	GO:0001947	94	0.032	Zebrafish
positive regulation of transport	GO:0051050	2	0.032
positive regulation of gene expression	GO:0010628	71	0.031
negative regulation of reproductive process	GO:2000242	3	0.031
regulation of biological quality	GO:0065008	263	0.030	Fly
negative regulation of gene expression	GO:0010629	65	0.030	Fly
embryonic heart tube morphogenesis	GO:0003143	108	0.029	Zebrafish
formation of primary germ layer	GO:0001704	62	0.029	Zebrafish
cellular ketone metabolic process	GO:0042180	11	0.029
blood vessel morphogenesis	GO:0048514	216	0.029
embryonic organ development	GO:0048568	381	0.029	Zebrafish Mouse
meiotic nuclear division	GO:0007126	4	0.029
positive regulation of secretion by cell	GO:1903532	1	0.028
phagocytosis	GO:0006909	3	0.028
female gamete generation	GO:0007292	14	0.028	Fly
small molecule metabolic process	GO:0044281	77	0.028
endoderm development	GO:0007492	49	0.028	Zebrafish Mouse
positive regulation of macromolecule metabolic process	GO:0010604	93	0.028
neuron differentiation	GO:0030182	353	0.028
embryonic organ morphogenesis	GO:0048562	274	0.028	Zebrafish
immune system process	GO:0002376	241	0.027	Zebrafish Fly
protein complex biogenesis	GO:0070271	30	0.027	Zebrafish
striated muscle cell development	GO:0055002	108	0.027	Zebrafish Mouse
muscle cell differentiation	GO:0042692	139	0.027	Zebrafish Mouse
response to stress	GO:0006950	263	0.027
autophagy	GO:0006914	4	0.026
cell migration	GO:0016477	237	0.026	Zebrafish Fly
heart jogging	GO:0003146	40	0.026	Zebrafish
dorsal ventral pattern formation	GO:0009953	125	0.025	Zebrafish Fly
lipid metabolic process	GO:0006629	52	0.025
small molecule catabolic process	GO:0044282	3	0.025
segmentation	GO:0035282	97	0.025	Mouse
stem cell division	GO:0017145	1	0.025	Fly
regulation of rna metabolic process	GO:0051252	224	0.024	Human Zebrafish Fly
cellular response to chemical stimulus	GO:0070887	157	0.024	Fly
single organism transport	GO:0044765	206	0.024
regulation of neurotransmitter transport	GO:0051588	1	0.024
response to external biotic stimulus	GO:0043207	97	0.024
apoptotic process involved in development	GO:1902742	2	0.023
oxoacid metabolic process	GO:0043436	31	0.023
regulation of transcription from rna polymerase ii promoter	GO:0006357	114	0.023	Human Zebrafish Fly
muscle cell development	GO:0055001	115	0.023	Zebrafish Mouse
gastrulation	GO:0007369	208	0.023	Zebrafish Mouse
regulation of macromolecule metabolic process	GO:0060255	317	0.023	Human Zebrafish Fly
regulation of signal transduction	GO:0009966	225	0.023	Human
positive regulation of cell activation	GO:0050867	1	0.023
positive regulation of catabolic process	GO:0009896	4	0.023
organonitrogen compound biosynthetic process	GO:1901566	47	0.022
macroautophagy	GO:0016236	1	0.022
response to corticosteroid	GO:0031960	1	0.022
organic cyclic compound biosynthetic process	GO:1901362	223	0.022	Zebrafish Fly
cell morphogenesis involved in differentiation	GO:0000904	195	0.022
cell motility	GO:0048870	244	0.022	Zebrafish Fly
regulation of metal ion transport	GO:0010959	4	0.022
brain development	GO:0007420	293	0.021
phosphorus metabolic process	GO:0006793	109	0.021
cellular response to oxygen levels	GO:0071453	1	0.021
protein complex assembly	GO:0006461	30	0.021	Zebrafish
camera type eye development	GO:0043010	222	0.021
leukocyte proliferation	GO:0070661	1	0.021
positive regulation of lipid metabolic process	GO:0045834	1	0.021
cellular response to xenobiotic stimulus	GO:0071466	35	0.021
organic acid metabolic process	GO:0006082	31	0.021
epithelial cell differentiation	GO:0030855	116	0.021	Human Fly
axis specification	GO:0009798	43	0.020	Zebrafish Mouse Fly
neuron projection development	GO:0031175	180	0.020
cellular hormone metabolic process	GO:0034754	19	0.020
positive regulation of biosynthetic process	GO:0009891	68	0.020
regulation of transcription from rna polymerase ii promoter involved in heart development	GO:1901213	15	0.020	Zebrafish
growth	GO:0040007	174	0.020	Fly
spemann organizer formation at the embryonic shield	GO:0060063	2	0.019
epithelial tube morphogenesis	GO:0060562	148	0.019	Zebrafish Fly
single organism organelle organization	GO:1902589	199	0.019
synaptic growth at neuromuscular junction	GO:0051124	2	0.019
sensory organ development	GO:0007423	393	0.019	Human Zebrafish Fly
central nervous system development	GO:0007417	387	0.019
regulation of embryonic development	GO:0045995	47	0.019	Zebrafish
oogenesis	GO:0048477	14	0.019	Fly
single organism biosynthetic process	GO:0044711	71	0.019
fertilization	GO:0009566	3	0.019
response to lipid	GO:0033993	60	0.018
positive regulation of cellular component biogenesis	GO:0044089	3	0.018
morphogenesis of an epithelial sheet	GO:0002011	49	0.018
positive regulation of secretion	GO:0051047	1	0.018
muscle structure development	GO:0061061	196	0.018	Zebrafish Mouse Fly
establishment of localization	GO:0051234	244	0.018
response to vitamin	GO:0033273	3	0.018
cytoplasm organization	GO:0007028	4	0.018
response to hexose	GO:0009746	3	0.017
reactive nitrogen species metabolic process	GO:2001057	0	0.017
cell fate commitment	GO:0045165	99	0.017	Human Zebrafish Fly
regulation of mrna processing	GO:0050684	3	0.017
negative regulation of signaling	GO:0023057	96	0.017	Human
developmental growth	GO:0048589	166	0.017	Fly
cellular response to extracellular stimulus	GO:0031668	2	0.017
regulation of skeletal muscle tissue development	GO:0048641	4	0.017	Mouse
somite development	GO:0061053	96	0.017	Mouse
transmembrane transport	GO:0055085	120	0.017
positive regulation of nitrogen compound metabolic process	GO:0051173	69	0.017
phosphate containing compound metabolic process	GO:0006796	108	0.016
cell morphogenesis involved in neuron differentiation	GO:0048667	163	0.016
protein metabolic process	GO:0019538	183	0.016
positive regulation of molecular function	GO:0044093	33	0.016
negative regulation of protein complex assembly	GO:0031333	1	0.016
eye photoreceptor cell differentiation	GO:0001754	45	0.016
adult behavior	GO:0030534	2	0.016
oocyte differentiation	GO:0009994	14	0.016	Fly
response to carbohydrate	GO:0009743	3	0.016
carboxylic acid metabolic process	GO:0019752	22	0.016
regulation of circadian rhythm	GO:0042752	4	0.016
generation of neurons	GO:0048699	385	0.015
regulation of endodermal cell differentiation	GO:1903224	15	0.015	Zebrafish
olfactory bulb development	GO:0021772	4	0.015
cell death	GO:0008219	121	0.015
cellular amine metabolic process	GO:0044106	2	0.015
calcium ion import	GO:0070509	4	0.015
cell migration involved in gastrulation	GO:0042074	79	0.015	Zebrafish
organelle organization	GO:0006996	227	0.015	Fly
positive regulation of muscle organ development	GO:0048636	1	0.015	Fly
germ cell development	GO:0007281	22	0.015	Fly
organelle fission	GO:0048285	23	0.015
response to other organism	GO:0051707	97	0.015
regulation of autophagy	GO:0010506	3	0.015
somitogenesis	GO:0001756	87	0.015	Mouse
cellular component movement	GO:0006928	335	0.015	Zebrafish Fly
macromolecule biosynthetic process	GO:0009059	227	0.015	Zebrafish Fly
response to organic substance	GO:0010033	153	0.015
regulation of response to nutrient levels	GO:0032107	1	0.015
meiotic chromosome segregation	GO:0045132	3	0.015
meiosis i	GO:0007127	1	0.014
developmental process involved in reproduction	GO:0003006	27	0.014	Fly
response to xenobiotic stimulus	GO:0009410	45	0.014
gland development	GO:0048732	143	0.014	Zebrafish Fly
head development	GO:0060322	303	0.014
3 utr mediated mrna stabilization	GO:0070935	3	0.014
camera type eye photoreceptor cell differentiation	GO:0060219	19	0.014
cell part morphogenesis	GO:0032990	246	0.014
cell projection organization	GO:0030030	284	0.014
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	1	0.014
retina morphogenesis in camera type eye	GO:0060042	79	0.014
eye morphogenesis	GO:0048592	144	0.014	Fly
anterior posterior pattern specification	GO:0009952	152	0.014	Mouse Fly
regulation of cell activation	GO:0050865	1	0.014
regulation of cellular amine metabolic process	GO:0033238	0	0.014
female gonad development	GO:0008585	4	0.014
inositol lipid mediated signaling	GO:0048017	2	0.014
regulation of programmed cell death	GO:0043067	101	0.014
determination of heart left right asymmetry	GO:0061371	117	0.014	Zebrafish
septum transversum development	GO:0003343	4	0.013	Zebrafish
cellular response to hypoxia	GO:0071456	1	0.013
cell recognition	GO:0008037	19	0.013
negative regulation of nucleobase containing compound metabolic process	GO:0045934	59	0.013
cell surface receptor signaling pathway	GO:0007166	325	0.013	Human Zebrafish Fly
intracellular receptor signaling pathway	GO:0030522	30	0.013
ion transport	GO:0006811	114	0.013
regulation of cell cycle	GO:0051726	52	0.013
apoptotic process involved in morphogenesis	GO:0060561	2	0.013
skeletal muscle fiber development	GO:0048741	35	0.013	Mouse
positive regulation of rna biosynthetic process	GO:1902680	57	0.013
positive regulation of response to stimulus	GO:0048584	80	0.013
amine metabolic process	GO:0009308	2	0.013
photoreceptor cell differentiation	GO:0046530	55	0.013
female meiotic division	GO:0007143	2	0.013
nucleic acid templated transcription	GO:0097659	181	0.013	Zebrafish Fly
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	1	0.013
negative regulation of cell death	GO:0060548	60	0.013
regulation of protein polymerization	GO:0032271	2	0.012
localization of cell	GO:0051674	244	0.012	Zebrafish Fly
positive regulation of multi organism process	GO:0043902	3	0.012
regulation of binding	GO:0051098	3	0.012
response to abiotic stimulus	GO:0009628	122	0.012
anterior posterior axis specification	GO:0009948	20	0.012	Mouse
regulation of synapse assembly	GO:0051963	3	0.012
negative regulation of metabolic process	GO:0009892	86	0.012	Fly
multi organism reproductive process	GO:0044703	36	0.012	Fly
positive regulation of cytoskeleton organization	GO:0051495	3	0.012
negative regulation of multi organism process	GO:0043901	3	0.012
water homeostasis	GO:0030104	4	0.012
mitotic cell cycle	GO:0000278	64	0.012
aging	GO:0007568	2	0.012
protein polymerization	GO:0051258	4	0.012
regulation of cytokine production	GO:0001817	3	0.012
transcription dna templated	GO:0006351	181	0.012	Zebrafish Fly
exocytosis	GO:0006887	1	0.012
transcription from rna polymerase ii promoter	GO:0006366	80	0.012	Zebrafish Fly
endodermal cell fate specification	GO:0001714	17	0.012	Zebrafish
axon development	GO:0061564	166	0.012
phagocytosis engulfment	GO:0006911	1	0.011
cellular response to decreased oxygen levels	GO:0036294	1	0.011
death	GO:0016265	121	0.011
negative regulation of programmed cell death	GO:0043069	58	0.011
regulation of neurotransmitter secretion	GO:0046928	1	0.011
macromolecular complex subunit organization	GO:0043933	74	0.011	Zebrafish
cell matrix adhesion	GO:0007160	4	0.011
neurotransmitter secretion	GO:0007269	2	0.011
neuroblast proliferation	GO:0007405	2	0.011
cellular protein metabolic process	GO:0044267	129	0.011
cell morphogenesis	GO:0000902	289	0.011
olfactory lobe development	GO:0021988	4	0.011
stem cell maintenance	GO:0019827	4	0.011	Fly
regulation of multicellular organismal development	GO:2000026	223	0.011	Human Zebrafish Mouse Fly
positive regulation of gtpase activity	GO:0043547	1	0.011
regulation of sodium ion transport	GO:0002028	2	0.011
lymphocyte proliferation	GO:0046651	1	0.011
cell substrate adhesion	GO:0031589	4	0.011
negative regulation of endodermal cell differentiation	GO:1903225	8	0.011	Zebrafish
long chain fatty acid biosynthetic process	GO:0042759	1	0.011
dicarboxylic acid metabolic process	GO:0043648	1	0.011
multicellular organism growth	GO:0035264	4	0.011
gliogenesis	GO:0042063	45	0.011
neural retina development	GO:0003407	49	0.011
regionalization	GO:0003002	274	0.011	Zebrafish Mouse Fly
transport	GO:0006810	220	0.011
negative regulation of nuclear division	GO:0051784	3	0.011
cellular response to antibiotic	GO:0071236	1	0.011
response to antibiotic	GO:0046677	1	0.011
mononuclear cell proliferation	GO:0032943	1	0.011
cellular component morphogenesis	GO:0032989	336	0.011	Fly
eye development	GO:0001654	277	0.011	Human Fly
spermatid development	GO:0007286	2	0.011
regulation of blood vessel size	GO:0050880	2	0.011
cellular protein modification process	GO:0006464	100	0.011
guanosine containing compound metabolic process	GO:1901068	4	0.011
muscle organ development	GO:0007517	101	0.011	Mouse Fly
chemotaxis	GO:0006935	104	0.011	Fly
response to amino acid	GO:0043200	2	0.010
meiosis ii	GO:0007135	1	0.010
neuron projection guidance	GO:0097485	86	0.010
modification dependent macromolecule catabolic process	GO:0043632	3	0.010
epiboly	GO:0090504	41	0.010
production of molecular mediator of immune response	GO:0002440	2	0.010
retinal rod cell development	GO:0046548	4	0.010
skeletal system development	GO:0001501	181	0.010	Human
proteolysis involved in cellular protein catabolic process	GO:0051603	3	0.010
regulation of purine nucleotide catabolic process	GO:0033121	2	0.010
cellular response to starvation	GO:0009267	1	0.010
proteasomal protein catabolic process	GO:0010498	2	0.010
response to hydrogen peroxide	GO:0042542	3	0.010
axonogenesis	GO:0007409	152	0.010

dvr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.033	Human

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