Danio rerio

0 known processes

mep1b

meprin A, beta

(Aliases: si:ch211-191a24.6,zgc:153272,MGC153272)

mep1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.095
agingGO:000756820.071
Worm
establishment of localizationGO:00512342440.071
Mouse
transmembrane transportGO:00550851200.068
lipid storageGO:001991510.064
Worm
maintenance of locationGO:005123540.061
Worm
multicellular organism growthGO:003526440.054
regulation of biological qualityGO:00650082630.053
Worm
positive regulation of transportGO:005105020.052
cell surface receptor signaling pathwayGO:00071663250.052
Zebrafish
regulation of protein transportGO:005122330.049
regulation of multicellular organism growthGO:004001440.048
single organism localizationGO:19025782250.047
cellular biosynthetic processGO:00442492860.047
regulation of establishment of protein localizationGO:007020140.045
immune system processGO:00023762410.045
Zebrafish
transportGO:00068102200.044
Mouse
biosynthetic processGO:00090582940.042
regulation of multicellular organismal processGO:00512392770.042
Zebrafish
signal transductionGO:00071654550.041
Zebrafish
establishment of protein localization to organelleGO:007259440.039
nucleocytoplasmic transportGO:000691340.039
organic substance biosynthetic processGO:19015762890.038
protein localization to nucleusGO:003450430.037
transcription dna templatedGO:00063511810.037
single organism transportGO:00447652060.036
response to stressGO:00069502630.036
blood vessel morphogenesisGO:00485142160.036
Zebrafish
heterocycle biosynthetic processGO:00181302150.035
regulation of cytokine productionGO:000181730.035
g protein coupled receptor signaling pathwayGO:0007186740.035
regulation of nucleobase containing compound metabolic processGO:00192192500.035
Zebrafish
ion transportGO:00068111140.034
ion transmembrane transportGO:0034220910.034
vasculature developmentGO:00019442780.034
Zebrafish
positive regulation of cytokine productionGO:000181920.034
regulation of inflammatory responseGO:005072720.033
cellular macromolecule metabolic processGO:00442603910.033
regulation of metal ion transportGO:001095940.032
amine metabolic processGO:000930820.032
regulation of cellular biosynthetic processGO:00313262450.032
Zebrafish
nuclear importGO:005117030.032
nucleobase containing compound biosynthetic processGO:00346542050.032
cellular response to molecule of bacterial originGO:007121930.032
cellular amine metabolic processGO:004410620.031
response to external stimulusGO:00096052640.031
regulation of cell communicationGO:00106462320.031
Zebrafish
cognitionGO:005089010.030
regulation of tube sizeGO:003515020.030
adult behaviorGO:003053420.030
protein importGO:001703830.029
protein import into nucleusGO:000660630.029
single organism metabolic processGO:00447102170.029
regulation of nitrogen compound metabolic processGO:00511712510.029
Zebrafish
protein secretionGO:000930610.029
nitrogen compound metabolic processGO:00068073190.029
regionalizationGO:00030022740.029
Zebrafish
nuclear transportGO:005116940.029
response to chemicalGO:00422213200.029
compound eye developmentGO:004874920.028
regulation of primary metabolic processGO:00800903110.028
Zebrafish
regulation of gene expressionGO:00104682650.028
Zebrafish
sensory perception of chemical stimulusGO:000760630.028
positive regulation of secretion by cellGO:190353210.027
positive regulation of biological processGO:00485182530.027
Zebrafish
organic cyclic compound biosynthetic processGO:19013622230.027
cellular response to external stimulusGO:007149620.027
cellular carbohydrate metabolic processGO:004426240.026
cellular response to lipopolysaccharideGO:007122230.026
blood vessel developmentGO:00015682460.026
Zebrafish
response to monosaccharideGO:003428430.026
embryonic organ developmentGO:00485683810.026
Zebrafish
mitochondrion organizationGO:000700540.026
cellular response to extracellular stimulusGO:003166820.026
response to organic substanceGO:00100331530.026
cellular ketone metabolic processGO:0042180110.026
positive regulation of cellular catabolic processGO:003133130.026
regulation of sodium ion transportGO:000202820.026
response to hexoseGO:000974630.026
response to carbohydrateGO:000974330.025
carboxylic acid metabolic processGO:0019752220.025
oxoacid metabolic processGO:0043436310.025
phagocytosisGO:000690930.025
regulation of macromolecule metabolic processGO:00602553170.025
Zebrafish
neuron neuron synaptic transmissionGO:000727010.024
regulation of cellular metabolic processGO:00313233200.024
Zebrafish
regulation of cellular amine metabolic processGO:003323800.024
organic acid metabolic processGO:0006082310.024
regulation of cellular amino acid metabolic processGO:000652100.024
regulation of cell activationGO:005086510.024
regulation of synaptic plasticityGO:004816710.024
regulation of phGO:000688530.024
protein targeting to nucleusGO:004474430.023
regulation of cytoplasmic transportGO:190364940.023
positive regulation of catabolic processGO:000989640.023
peptide transportGO:001583310.023
inorganic anion transportGO:0015698250.023
small molecule metabolic processGO:0044281770.023
cellular nitrogen compound metabolic processGO:00346412900.023
nucleobase containing compound metabolic processGO:00061392740.023
regulation of cellular ketone metabolic processGO:001056570.023
dorsal ventral pattern formationGO:00099531250.022
Zebrafish
hemopoiesisGO:00300971830.022
Zebrafish
stem cell proliferationGO:007208940.022
system processGO:00030081850.022
response to drugGO:004249330.022
sodium ion transmembrane transportGO:0035725210.022
synaptic growth at neuromuscular junctionGO:005112420.022
regulation of cellular macromolecule biosynthetic processGO:20001122220.022
Zebrafish
response to glucoseGO:000974930.022
heterocycle metabolic processGO:00464832900.022
positive regulation of cell cycleGO:004578730.022
organonitrogen compound metabolic processGO:1901564740.022
inorganic ion transmembrane transportGO:0098660570.022
regulation of protein ubiquitinationGO:003139630.021
regulation of blood pressureGO:000821710.021
locomotionGO:00400113130.021
Worm
single organism nuclear importGO:190259330.021
regulation of blood vessel sizeGO:005088020.021
macromolecule biosynthetic processGO:00090592270.021
hematopoietic or lymphoid organ developmentGO:00485341910.021
Zebrafish
organic substance transportGO:0071702580.021
rna metabolic processGO:00160702190.021
peptide metabolic processGO:000651810.020
cellular nitrogen compound biosynthetic processGO:00442712180.020
leukocyte proliferationGO:007066110.020
complement activationGO:000695630.020
response to other organismGO:0051707970.020
positive regulation of secretionGO:005104710.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
regulation of protein localization to nucleusGO:190018020.020
gene expressionGO:00104672520.020
neurotransmitter transportGO:000683620.020
regulation of signalingGO:00230512350.020
Zebrafish
cytokinesisGO:000091030.020
cation transportGO:0006812810.019
regulation of metabolic processGO:00192223590.019
Zebrafish
cellular response to biotic stimulusGO:007121630.019
positive regulation of cellular amine metabolic processGO:003324000.019
cellular response to chemical stimulusGO:00708871570.019
proteolysis involved in cellular protein catabolic processGO:005160330.019
sensory perception of smellGO:000760820.019
cellular amino acid metabolic processGO:000652070.019
negative regulation of protein transportGO:005122430.019
regulation of macromolecule biosynthetic processGO:00105562250.019
Zebrafish
regulation of developmental processGO:00507932470.019
Zebrafish
regulation of protein import into nucleusGO:004230620.019
hatchingGO:003518840.019
Zebrafish
positive regulation of inflammatory responseGO:005072910.019
fatty acid transportGO:001590810.019
growthGO:00400071740.019
response to woundingGO:00096111160.019
inorganic cation transmembrane transportGO:0098662500.019
cellular macromolecule biosynthetic processGO:00346452240.019
alcohol biosynthetic processGO:004616520.019
regulation of nucleocytoplasmic transportGO:004682220.018
female sex differentiationGO:004666040.018
regulation of intracellular protein transportGO:003315730.018
gastrulationGO:00073692080.018
Zebrafish
response to biotic stimulusGO:0009607970.018
positive regulation of cellular component biogenesisGO:004408930.018
negative regulation of protein phosphorylationGO:000193340.018
cellular response to nutrient levelsGO:003166920.018
lipid homeostasisGO:005508830.018
regulation of ion transmembrane transporter activityGO:003241220.018
regulation of peptidyl tyrosine phosphorylationGO:005073010.018
angiogenesisGO:00015251580.018
Zebrafish
cation transmembrane transportGO:0098655650.018
regulation of epithelial cell proliferationGO:005067830.018
regulation of response to stimulusGO:00485832690.018
Zebrafish
organism emergence from protective structureGO:007168440.018
Zebrafish
regulation of biosynthetic processGO:00098892500.018
Zebrafish
nucleic acid templated transcriptionGO:00976591810.018
cellular aromatic compound metabolic processGO:00067252950.018
chordate embryonic developmentGO:00430092710.018
regulation of protein complex assemblyGO:004325430.017
eye developmentGO:00016542770.017
protein metabolic processGO:00195381830.017
Zebrafish Worm
digestive system developmentGO:00551232890.017
Zebrafish
positive regulation of immune effector processGO:000269930.017
hormone secretionGO:004687920.017
regulation of muscle contractionGO:000693730.017
regulation of protein targetingGO:190353320.017
regulation of bindingGO:005109830.017
sensory organ developmentGO:00074233930.017
regulation of nucleic acid templated transcriptionGO:19035062130.017
Zebrafish
monovalent inorganic cation transportGO:0015672420.017
regulation of transporter activityGO:003240920.017
negative regulation of biological processGO:00485193040.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.017
establishment of protein localization to plasma membraneGO:009000210.017
nucleic acid metabolic processGO:00903042440.017
response to bacteriumGO:0009617580.017
regulation of dna replicationGO:000627530.017
response to nutrientGO:000758430.017
cellular protein catabolic processGO:004425740.017
negative regulation of secretionGO:005104820.017
negative regulation of cellular processGO:00485232830.017
dicarboxylic acid transportGO:000683510.017
regulation of circadian rhythmGO:004275240.017
autophagyGO:000691440.017
cellular response to starvationGO:000926710.016
neurotransmitter secretionGO:000726920.016
determination of bilateral symmetryGO:00098552040.016
Zebrafish
tube morphogenesisGO:00352393490.016
Zebrafish
positive regulation of lymphocyte mediated immunityGO:000270810.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
brain developmentGO:00074202930.016
hormone transportGO:000991420.016
endocrine processGO:005088620.016
negative regulation of secretion by cellGO:190353120.016
regulation of response to nutrient levelsGO:003210710.016
regulation of synapse assemblyGO:005196330.016
positive regulation of cell activationGO:005086710.016
response to vitaminGO:003327330.016
response to external biotic stimulusGO:0043207970.016
mononuclear cell proliferationGO:003294310.016
modification dependent protein catabolic processGO:001994130.016
regulation of protein catabolic processGO:004217610.016
guanosine containing compound metabolic processGO:190106840.016
sodium ion transportGO:0006814240.016
g1 s transition of mitotic cell cycleGO:000008210.015
embryo development ending in birth or egg hatchingGO:00097922710.015
Worm
carbohydrate homeostasisGO:003350010.015
specification of symmetryGO:00097992040.015
Zebrafish
negative regulation of defense responseGO:003134820.015
cellular component disassemblyGO:002241110.015
generation of neuronsGO:00486993850.015
regulation of synapse organizationGO:005080730.015
modification dependent macromolecule catabolic processGO:004363230.015
aromatic compound biosynthetic processGO:00194382170.015
regulation of reproductive processGO:200024140.015
positive regulation of dna metabolic processGO:005105410.015
regulation of calcium ion transportGO:005192420.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015
internal peptidyl lysine acetylationGO:001839320.015
negative regulation of catabolic processGO:000989530.015
energy reserve metabolic processGO:000611220.015
positive regulation of blood circulationGO:190352420.015
transcription from rna polymerase ii promoterGO:0006366800.015
regulation of nucleotide catabolic processGO:003081120.015
tissue remodelingGO:004877140.014
ubiquitin dependent protein catabolic processGO:000651130.014
peptidyl lysine acetylationGO:001839420.014
multi organism processGO:00517041340.014
stem cell maintenanceGO:001982740.014
regulation of autophagyGO:001050630.014
germ line stem cell maintenanceGO:003071820.014
leukocyte mediated cytotoxicityGO:000190910.014
regulation of purine nucleotide catabolic processGO:003312120.014
lipid catabolic processGO:001604240.014
regulation of nucleoside metabolic processGO:000911820.014
gtp catabolic processGO:000618420.014
regulation of signal transductionGO:00099662250.014
Zebrafish
immunoglobulin mediated immune responseGO:001606430.014
female gonad developmentGO:000858540.014
secondary metabolic processGO:001974830.014
multi organism cellular processGO:004476420.014
response to abiotic stimulusGO:00096281220.014
morphogenesis of an epitheliumGO:00020093330.014
meiotic cell cycle processGO:190304630.014
organic cyclic compound metabolic processGO:19013603010.014
developmental growthGO:00485891660.014
i kappab kinase nf kappab signalingGO:000724940.014
inositol lipid mediated signalingGO:004801720.014
carbohydrate biosynthetic processGO:001605110.014
regulation of localizationGO:00328791040.014
homeostatic processGO:00425921420.014
spermatid developmentGO:000728620.014
positive regulation of leukocyte mediated cytotoxicityGO:000191210.014
regulation of systemic arterial blood pressureGO:000307310.014
response to endogenous stimulusGO:0009719830.014
regulation of stem cell proliferationGO:007209120.014
cytoskeleton dependent cytokinesisGO:006164030.014
gtp metabolic processGO:004603940.014
negative regulation of protein kinase activityGO:000646940.014
response to alkaloidGO:004327920.014
single organism biosynthetic processGO:0044711710.014
lymphocyte proliferationGO:004665110.014
glucose homeostasisGO:004259310.013
positive regulation of map kinase activityGO:004340630.013
negative regulation of intracellular transportGO:003238730.013
chemosensory behaviorGO:000763510.013
regulation of gtpase activityGO:004308720.013
localization of cellGO:00516742440.013
metal ion transportGO:0030001580.013
positive regulation of glucose transportGO:001082810.013
protein localization to plasma membraneGO:007265910.013
head developmentGO:00603223030.013
b cell activationGO:004211320.013
neuroblast proliferationGO:000740520.013
cellular component biogenesisGO:00440851780.013
response to amino acidGO:004320020.013
exocytosisGO:000688710.013
regulation of striated muscle contractionGO:000694220.013
apoptotic processGO:00069151160.013
antimicrobial humoral responseGO:001973020.013
positive regulation of epithelial cell proliferationGO:005067910.013
multicellular organismal metabolic processGO:004423620.013
epithelial cell differentiationGO:00308551160.013
Zebrafish
defense responseGO:0006952470.013
regulation of transcription dna templatedGO:00063552130.013
Zebrafish
cellular amide metabolic processGO:004360340.013
smooth muscle contractionGO:000693920.013
pyruvate metabolic processGO:000609010.013
atp catabolic processGO:000620040.013
protein activation cascadeGO:007237660.013
positive regulation of cellular processGO:00485222010.013
Zebrafish
post embryonic organ developmentGO:004856940.013
cell morphogenesisGO:00009022890.012
negative regulation of nucleocytoplasmic transportGO:004682320.012
protein stabilizationGO:005082120.012
gland developmentGO:00487321430.012
macromolecule localizationGO:0033036540.012
Worm
spermatid differentiationGO:004851520.012
positive regulation of nucleotide catabolic processGO:003081310.012
cellular component morphogenesisGO:00329893360.012
production of molecular mediator of immune responseGO:000244020.012
cellular response to organic substanceGO:00713101050.012
regulation of hormone secretionGO:004688320.012
regulation of i kappab kinase nf kappab signalingGO:004312240.012
rna localizationGO:000640340.012
regulation of transmembrane transporter activityGO:002289820.012
neuron differentiationGO:00301823530.012
digestive tract developmentGO:00485652650.012
Zebrafish
anion transportGO:0006820380.012
negative regulation of cytoplasmic transportGO:190365020.012
protein acetylationGO:000647320.012
cellular response to reactive oxygen speciesGO:003461420.012
cell deathGO:00082191210.012
regulation of production of molecular mediator of immune responseGO:000270010.012
rna biosynthetic processGO:00327741810.012
regulation of neural precursor cell proliferationGO:200017730.012
phagocytosis engulfmentGO:000691110.012
positive regulation of response to stimulusGO:0048584800.012
Zebrafish
amino acid transportGO:000686520.012
neurological system processGO:0050877620.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
digestive tract morphogenesisGO:00485462310.012
Zebrafish
positive regulation of gtpase activityGO:004354710.012
response to oxygen containing compoundGO:1901700550.012
embryonic hemopoiesisGO:0035162530.012
Zebrafish
neuromuscular process controlling balanceGO:005088530.012
cell motilityGO:00488702440.012
protein heterooligomerizationGO:005129110.012
b cell mediated immunityGO:001972430.012
multicellular organismal response to stressGO:003355520.012
somatic muscle developmentGO:000752540.012
somite developmentGO:0061053960.012
epithelial tube morphogenesisGO:00605621480.012
cell substrate adhesionGO:003158940.012
chloride transmembrane transportGO:190247640.011
cellular component movementGO:00069283350.011
negative regulation of kinase activityGO:003367340.011
negative regulation of response to stimulusGO:00485851040.011
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.011
cell cycle g1 s phase transitionGO:004484310.011
actin filament based movementGO:003004810.011
regulation of cellular protein catabolic processGO:190336210.011
internal protein amino acid acetylationGO:000647520.011
synaptic vesicle localizationGO:009747910.011
development of primary female sexual characteristicsGO:004654540.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
Zebrafish
positive regulation of nucleoside metabolic processGO:004597910.011
negative regulation of cellular catabolic processGO:003133030.011
bmp signaling pathwayGO:0030509520.011
Zebrafish
nitric oxide biosynthetic processGO:000680920.011
membrane invaginationGO:001032410.011
negative regulation of cytokine productionGO:000181810.011
liver developmentGO:0001889960.011
protein dephosphorylationGO:000647030.011
fat soluble vitamin metabolic processGO:000677540.011
reactive oxygen species biosynthetic processGO:190340910.011
guanosine containing compound catabolic processGO:190106920.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
heart developmentGO:00075073130.011
sensory perception of painGO:001923310.011
negative regulation of protein import into nucleusGO:004230820.011
regulation of cellular phGO:003064110.011
organelle organizationGO:00069962270.011
neuron developmentGO:00486662620.011
protein acylationGO:004354330.011
regulation of reactive oxygen species metabolic processGO:200037720.011
regulation of dendrite developmentGO:005077330.011
stem cell divisionGO:001714510.011
single fertilizationGO:000733830.011
phosphatidylinositol 3 kinase signalingGO:001406520.011
positive regulation of multi organism processGO:004390230.011
regulation of rna biosynthetic processGO:20011412130.011
Zebrafish
embryonic organ morphogenesisGO:00485622740.011
regulation of lipid transportGO:003236840.011
positive regulation of cell killingGO:003134320.011
negative regulation of neural precursor cell proliferationGO:200017810.011
regulation of anatomical structure morphogenesisGO:00226031300.011
Zebrafish
stem cell fate commitmentGO:004886510.011
golgi vesicle transportGO:004819330.011
synaptic vesicle transportGO:004848910.011
regulation of carbohydrate metabolic processGO:000610940.011
centrosome organizationGO:005129710.011
establishment of synaptic vesicle localizationGO:009748010.011
macromolecular complex disassemblyGO:003298410.011
ribonucleoside monophosphate catabolic processGO:000915840.010
monoamine transportGO:001584410.010
regulation of gtp catabolic processGO:003312420.010
heart processGO:0003015710.010
circulatory system processGO:0003013870.010
cell migrationGO:00164772370.010
central nervous system developmentGO:00074173870.010
regulation of multicellular organismal developmentGO:20000262230.010
Zebrafish
hepaticobiliary system developmentGO:0061008980.010
regulation of synaptic growth at neuromuscular junctionGO:000858210.010
regulation of rna metabolic processGO:00512522240.010
Zebrafish
regulation of membrane potentialGO:0042391230.010
response to topologically incorrect proteinGO:003596620.010
extrinsic apoptotic signaling pathwayGO:009719130.010
positive regulation of stem cell proliferationGO:200064810.010
positive regulation of lipase activityGO:006019310.010
somitogenesisGO:0001756870.010
determination of dorsal ventral asymmetryGO:0048262340.010
Zebrafish
phosphorus metabolic processGO:00067931090.010
toll like receptor signaling pathwayGO:000222440.010
endosomal transportGO:001619720.010
positive regulation of purine nucleotide catabolic processGO:003312310.010
positive regulation of apoptotic signaling pathwayGO:200123510.010
membrane hyperpolarizationGO:006008110.010
humoral immune response mediated by circulating immunoglobulinGO:000245530.010
chemical homeostasisGO:0048878490.010

mep1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
nervous system diseaseDOID:86300.023
disease of metabolismDOID:001466700.017
musculoskeletal system diseaseDOID:1700.013
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013
organ system cancerDOID:005068600.012
cardiovascular system diseaseDOID:128700.011
eye diseaseDOID:561400.011
eye and adnexa diseaseDOID:149200.011
sensory system diseaseDOID:005015500.011
inherited metabolic disorderDOID:65500.010