Danio rerio

0 known processes

cdkn1b

cyclin-dependent kinase inhibitor 1b (p27, kip1)

(Aliases: wu:fb64g10,wu:fb63g10,sb:cb611,wu:fe18e03)

cdkn1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.223
negative regulation of biological processGO:00485193040.169
regulation of metabolic processGO:00192223590.144
organic cyclic compound metabolic processGO:19013603010.133
signal transductionGO:00071654550.122
gene expressionGO:00104672520.119
cellular macromolecule biosynthetic processGO:00346452240.119
sensory organ developmentGO:00074233930.116
cellular nitrogen compound metabolic processGO:00346412900.114
cell motilityGO:00488702440.113
cell surface receptor signaling pathwayGO:00071663250.107
generation of neuronsGO:00486993850.105
cognitionGO:005089010.104
response to chemicalGO:00422213200.100
hematopoietic or lymphoid organ developmentGO:00485341910.092
single organism localizationGO:19025782250.090
regulation of developmental processGO:00507932470.084
regulation of biological qualityGO:00650082630.083
cellular biosynthetic processGO:00442492860.083
localization of cellGO:00516742440.083
negative regulation of cellular processGO:00485232830.082
regulation of signalingGO:00230512350.082
regulation of response to stimulusGO:00485832690.082
tube morphogenesisGO:00352393490.081
regulation of extrinsic apoptotic signaling pathwayGO:200123630.079
maintenance of locationGO:005123540.079
biosynthetic processGO:00090582940.078
cellular component morphogenesisGO:00329893360.078
response to stressGO:00069502630.077
immune system developmentGO:00025201910.077
positive regulation of transportGO:005105020.075
regulation of gene expressionGO:00104682650.073
rna metabolic processGO:00160702190.070
cell migrationGO:00164772370.069
cellular component movementGO:00069283350.069
positive regulation of map kinase activityGO:004340630.069
small molecule metabolic processGO:0044281770.068
locomotionGO:00400113130.066
single organism metabolic processGO:00447102170.065
head developmentGO:00603223030.065
regulation of primary metabolic processGO:00800903110.064
morphogenesis of an epitheliumGO:00020093330.064
multicellular organism growthGO:003526440.063
nucleobase containing compound metabolic processGO:00061392740.062
cellular amino acid metabolic processGO:000652070.062
protein localization to nucleusGO:003450430.061
brain developmentGO:00074202930.060
regulation of multicellular organismal developmentGO:20000262230.060
single organism transportGO:00447652060.060
regulation of multicellular organismal processGO:00512392770.060
agingGO:000756820.059
nitrogen compound metabolic processGO:00068073190.059
regulation of cell shapeGO:000836010.058
response to other organismGO:0051707970.057
regulation of signal transductionGO:00099662250.057
central nervous system developmentGO:00074173870.056
cellular ketone metabolic processGO:0042180110.055
regulation of biosynthetic processGO:00098892500.053
cellular macromolecule metabolic processGO:00442603910.053
regulation of cellular metabolic processGO:00313233200.052
regulation of peptidyl tyrosine phosphorylationGO:005073010.052
developmental growthGO:00485891660.051
rna biosynthetic processGO:00327741810.051
heterocycle metabolic processGO:00464832900.051
protein metabolic processGO:00195381830.050
transportGO:00068102200.050
regionalizationGO:00030022740.050
eye developmentGO:00016542770.049
eye morphogenesisGO:00485921440.049
regulation of nitrogen compound metabolic processGO:00511712510.048
regulation of multicellular organism growthGO:004001440.048
angiogenesisGO:00015251580.048
neuron differentiationGO:00301823530.048
positive regulation of biological processGO:00485182530.048
sulfur compound metabolic processGO:0006790130.047
establishment of localizationGO:00512342440.047
post embryonic organ developmentGO:004856940.046
regulation of localizationGO:00328791040.046
gland developmentGO:00487321430.046
phagocytosisGO:000690930.046
response to external stimulusGO:00096052640.045
digestive system developmentGO:00551232890.045
cell part morphogenesisGO:00329902460.045
regulation of anatomical structure morphogenesisGO:00226031300.045
apoptotic processGO:00069151160.045
cell projection morphogenesisGO:00488582440.045
regulation of cell communicationGO:00106462320.044
organic acid metabolic processGO:0006082310.044
hemopoiesisGO:00300971830.044
cellular aromatic compound metabolic processGO:00067252950.044
neuron developmentGO:00486662620.044
vasculature developmentGO:00019442780.043
nuclear transportGO:005116940.043
regulation of cellular amine metabolic processGO:003323800.043
single organism organelle organizationGO:19025891990.043
heart developmentGO:00075073130.043
programmed cell deathGO:00125011190.043
blood vessel developmentGO:00015682460.042
response to drugGO:004249330.042
cellular amine metabolic processGO:004410620.042
immune system processGO:00023762410.042
cellular protein metabolic processGO:00442671290.042
cytokinesisGO:000091030.041
organic substance biosynthetic processGO:19015762890.041
spermatid developmentGO:000728620.041
deathGO:00162651210.041
positive regulation of cellular processGO:00485222010.041
cell deathGO:00082191210.040
positive regulation of cell cycleGO:004578730.040
regulation of macromolecule metabolic processGO:00602553170.040
neuroblast proliferationGO:000740520.039
muscle structure developmentGO:00610611960.039
stem cell maintenanceGO:001982740.038
epithelial cell differentiationGO:00308551160.038
regulation of cellular biosynthetic processGO:00313262450.038
digestive tract morphogenesisGO:00485462310.038
alpha amino acid metabolic processGO:190160530.037
regulation of apoptotic processGO:0042981980.036
spermatid differentiationGO:004851520.036
regulation of cellular macromolecule biosynthetic processGO:20001122220.036
axon developmentGO:00615641660.036
regulation of cellular component organizationGO:0051128860.035
cellular component assemblyGO:00226071700.035
nucleocytoplasmic transportGO:000691340.035
multi organism processGO:00517041340.035
positive regulation of metabolic processGO:00098931080.034
positive regulation of catabolic processGO:000989640.034
regulation of cellular amino acid metabolic processGO:000652100.034
specification of symmetryGO:00097992040.033
regulation of nucleic acid templated transcriptionGO:19035062130.033
oxoacid metabolic processGO:0043436310.033
adult behaviorGO:003053420.033
positive regulation of cellular catabolic processGO:003133130.033
pigment granule transportGO:0051904190.032
regulation of nucleobase containing compound metabolic processGO:00192192500.032
extrinsic apoptotic signaling pathwayGO:009719130.032
regulation of calcium ion transportGO:005192420.032
determination of left right symmetryGO:00073681790.032
regulation of cellular ketone metabolic processGO:001056570.032
nucleobase containing compound biosynthetic processGO:00346542050.031
regulation of metal ion transportGO:001095940.031
macromolecule biosynthetic processGO:00090592270.031
stem cell differentiationGO:00488631170.031
lipid metabolic processGO:0006629520.031
regulation of reproductive processGO:200024140.031
response to carbohydrateGO:000974330.031
growthGO:00400071740.031
regulation of synapse organizationGO:005080730.031
carboxylic acid metabolic processGO:0019752220.030
neuron projection developmentGO:00311751800.030
organonitrogen compound metabolic processGO:1901564740.030
regulation of synaptic growth at neuromuscular junctionGO:000858210.030
cellular component biogenesisGO:00440851780.030
sensory organ morphogenesisGO:00905962000.030
digestive tract developmentGO:00485652650.030
aromatic compound biosynthetic processGO:00194382170.030
regulation of carbohydrate metabolic processGO:000610940.030
lipid storageGO:001991510.030
macromolecule modificationGO:00434121110.030
regulation of cell activationGO:005086510.029
striated muscle cell differentiationGO:00511461290.029
amine metabolic processGO:000930820.029
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.029
cellular response to chemical stimulusGO:00708871570.028
ameboidal type cell migrationGO:00016671430.028
b cell activationGO:004211320.028
ovulation cycleGO:004269820.028
cellular protein modification processGO:00064641000.028
response to endogenous stimulusGO:0009719830.028
regulation of cell deathGO:00109411030.028
positive regulation of cytosolic calcium ion concentrationGO:000720440.027
protein targeting to nucleusGO:004474430.027
lateral line system developmentGO:0048925760.027
cilium movementGO:0003341260.027
positive regulation of jnk cascadeGO:004633030.027
cell projection organizationGO:00300302840.027
positive regulation of cellular component biogenesisGO:004408930.027
intracellular signal transductionGO:0035556850.027
organelle localizationGO:0051640490.027
blood vessel morphogenesisGO:00485142160.026
positive regulation of cellular amino acid metabolic processGO:004576400.026
response to foodGO:003209410.026
axonogenesisGO:00074091520.026
positive regulation of cellular metabolic processGO:0031325940.026
cellular response to external stimulusGO:007149620.026
stem cell divisionGO:001714510.026
lymphocyte proliferationGO:004665110.026
single organism nuclear importGO:190259330.026
mechanosensory lateral line system developmentGO:0048881490.026
negative regulation of macromolecule metabolic processGO:0010605760.025
regulation of reactive oxygen species metabolic processGO:200037720.025
positive regulation of macromolecule metabolic processGO:0010604930.025
somatic muscle developmentGO:000752540.025
homeostatic processGO:00425921420.025
response to abiotic stimulusGO:00096281220.025
regulation of protein transportGO:005122330.025
negative regulation of metabolic processGO:0009892860.025
regulation of establishment of protein localizationGO:007020140.024
camera type eye developmentGO:00430102220.024
convergent extension involved in gastrulationGO:0060027710.024
homeostasis of number of cellsGO:0048872620.024
chemosensory behaviorGO:000763510.024
cellular nitrogen compound biosynthetic processGO:00442712180.024
segmentationGO:0035282970.024
guanosine containing compound metabolic processGO:190106840.024
organelle organizationGO:00069962270.024
positive regulation of cell activationGO:005086710.024
cell proliferationGO:0008283800.024
cellular response to organic substanceGO:00713101050.024
positive regulation of multicellular organismal processGO:0051240520.024
nucleic acid metabolic processGO:00903042440.024
nuclear importGO:005117030.024
erythrocyte homeostasisGO:0034101550.023
protein import into nucleusGO:000660630.023
regulation of macromolecule biosynthetic processGO:00105562250.023
antimicrobial humoral responseGO:001973020.023
positive regulation of cellular amine metabolic processGO:003324000.023
regulation of cellular component movementGO:0051270550.023
positive regulation of developmental processGO:0051094500.023
gtp metabolic processGO:004603940.023
negative regulation of cell deathGO:0060548600.023
positive regulation of nitrogen compound metabolic processGO:0051173690.022
regulation of cellular carbohydrate metabolic processGO:001067540.022
cellular modified amino acid metabolic processGO:000657530.022
enzyme linked receptor protein signaling pathwayGO:00071671060.022
protein importGO:001703830.022
regulation of molecular functionGO:0065009700.022
embryonic organ morphogenesisGO:00485622740.022
regulation of cytokine productionGO:000181730.022
positive regulation of signal transductionGO:0009967560.022
guanosine containing compound catabolic processGO:190106920.022
transcription dna templatedGO:00063511810.022
regulation of cell projection assemblyGO:006049140.022
regulation of purine nucleotide catabolic processGO:003312120.022
synaptic growth at neuromuscular junctionGO:005112420.022
epithelium migrationGO:0090132250.021
regulation of gtp catabolic processGO:003312420.021
response to organic substanceGO:00100331530.021
posterior lateral line developmentGO:0048916380.021
proteolysis involved in cellular protein catabolic processGO:005160330.021
cell divisionGO:0051301200.021
cellular localizationGO:0051641970.020
developmental pigmentationGO:0048066480.020
establishment of protein localization to organelleGO:007259440.020
stem cell proliferationGO:007208940.020
sensory perception of chemical stimulusGO:000760630.020
negative regulation of response to stimulusGO:00485851040.020
defense responseGO:0006952470.020
regulation of cytoplasmic transportGO:190364940.020
negative regulation of multicellular organismal processGO:0051241690.020
muscle organ developmentGO:00075171010.020
regulation of nervous system developmentGO:0051960900.020
glial cell migrationGO:000834730.020
somitogenesisGO:0001756870.020
multicellular organismal homeostasisGO:0048871290.020
regulation of synapse assemblyGO:005196330.020
exocytosisGO:000688710.020
erythrocyte differentiationGO:0030218540.020
regulation of rna metabolic processGO:00512522240.020
embryo development ending in birth or egg hatchingGO:00097922710.020
negative regulation of programmed cell deathGO:0043069580.020
heterocycle biosynthetic processGO:00181302150.020
modification dependent protein catabolic processGO:001994130.020
response to biotic stimulusGO:0009607970.019
ion homeostasisGO:0050801410.019
b cell differentiationGO:003018310.019
behaviorGO:0007610740.019
regulation of nucleotide catabolic processGO:003081120.019
embryonic pattern specificationGO:0009880440.019
system processGO:00030081850.019
epithelial cell migrationGO:0010631250.019
regulation of bindingGO:005109830.019
regulation of rna biosynthetic processGO:20011412130.019
mitotic cell cycleGO:0000278640.019
tissue migrationGO:0090130370.019
actin filament based movementGO:003004810.019
organelle assemblyGO:00709251100.019
regulation of wound healingGO:006104120.019
leukocyte proliferationGO:007066110.019
tissue regenerationGO:0042246740.019
cilium morphogenesisGO:0060271850.018
cellular response to oxygen levelsGO:007145310.018
regulation of nucleoside metabolic processGO:000911820.018
regulation of cell motilityGO:2000145460.018
negative regulation of gene expressionGO:0010629650.018
cellular protein catabolic processGO:004425740.018
positive regulation of response to stimulusGO:0048584800.018
protein localization to plasma membraneGO:007265910.018
single organism biosynthetic processGO:0044711710.018
cilium organizationGO:0044782710.018
negative regulation of signalingGO:0023057960.018
modification dependent macromolecule catabolic processGO:004363230.018
regulation of production of molecular mediator of immune responseGO:000270010.018
regenerationGO:0031099910.018
regulation of cell differentiationGO:00455951420.018
production of molecular mediator of immune responseGO:000244020.018
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.018
phosphate containing compound metabolic processGO:00067961080.018
determination of bilateral symmetryGO:00098552040.018
positive regulation of cellular biosynthetic processGO:0031328680.017
positive regulation of nucleobase containing compound metabolic processGO:0045935690.017
actin filament based processGO:0030029640.017
regulation of mrna processingGO:005068430.017
negative regulation of map kinase activityGO:004340720.017
embryonic organ developmentGO:00485683810.017
mononuclear cell proliferationGO:003294310.017
female gonad developmentGO:000858540.017
heart morphogenesisGO:00030071560.017
protein modification processGO:00362111000.017
organic cyclic compound biosynthetic processGO:19013622230.017
cellular response to molecule of bacterial originGO:007121930.017
retinal rod cell developmentGO:004654840.017
regulation of cell matrix adhesionGO:000195210.017
inner ear developmentGO:00488391260.017
notch signaling pathwayGO:0007219350.017
gliogenesisGO:0042063450.017
transcription from rna polymerase ii promoterGO:0006366800.017
cellular component assembly involved in morphogenesisGO:00109271070.017
forebrain developmentGO:0030900960.017
regulation of protein ubiquitinationGO:003139630.017
peptidyl serine phosphorylationGO:001810510.016
nucleic acid templated transcriptionGO:00976591810.016
regulation of transcription dna templatedGO:00063552130.016
regulation of protein metabolic processGO:0051246560.016
negative regulation of protein kinase activityGO:000646940.016
regulation of epithelial cell proliferationGO:005067830.016
regulation of leukocyte mediated immunityGO:000270310.016
negative regulation of apoptotic processGO:0043066550.016
cilium assemblyGO:0042384580.016
response to external biotic stimulusGO:0043207970.016
regulation of catalytic activityGO:0050790550.016
skeletal muscle tissue developmentGO:0007519670.016
cell chemotaxisGO:0060326170.016
dorsal ventral pattern formationGO:00099531250.016
cell morphogenesis involved in neuron differentiationGO:00486671630.016
neurological system processGO:0050877620.016
cellular response to decreased oxygen levelsGO:003629410.016
startle responseGO:000196440.016
sexual reproductionGO:0019953360.016
regulation of gtpase activityGO:004308720.016
vasculogenesisGO:0001570410.015
positive regulation of nucleoside metabolic processGO:004597910.015
negative regulation of cell communicationGO:0010648960.015
regulation of locomotionGO:0040012550.015
compound eye developmentGO:004874920.015
transmission of nerve impulseGO:0019226190.015
positive regulation of gtp catabolic processGO:003312610.015
pigment cell differentiationGO:0050931380.015
cartilage developmentGO:0051216960.015
positive regulation of nucleic acid templated transcriptionGO:1903508570.015
muscle cell migrationGO:001481240.015
regulation of response to nutrient levelsGO:003210710.015
cellular response to biotic stimulusGO:007121630.015
single organism cellular localizationGO:1902580460.015
somite developmentGO:0061053960.015
skeletal muscle organ developmentGO:0060538780.015
response to organic cyclic compoundGO:0014070510.015
gtp catabolic processGO:000618420.015
muscle cell developmentGO:00550011150.015
carbohydrate derivative metabolic processGO:1901135610.015
wound healingGO:0042060900.015
multi organism reproductive processGO:0044703360.015
rhythmic processGO:0048511210.015
response to virusGO:0009615210.015
glial cell differentiationGO:0010001420.015
cytoskeleton organizationGO:0007010960.015
membrane fusionGO:006102520.015
rna localizationGO:000640340.015
negative regulation of macromolecule biosynthetic processGO:0010558480.014
lamellipodium organizationGO:009758110.014
positive regulation of carbohydrate metabolic processGO:004591310.014
negative regulation of developmental processGO:0051093650.014
dicarboxylic acid metabolic processGO:004364810.014
regulation of protein complex assemblyGO:004325430.014
posterior lateral line system developmentGO:0048915460.014
positive regulation of secretionGO:005104710.014
activation of mapk activityGO:000018730.014
long chain fatty acid transportGO:001590910.014
myeloid cell homeostasisGO:0002262560.014
wnt signaling pathwayGO:0016055800.014
protein phosphorylationGO:0006468470.014
glucose importGO:004632320.014
cell projection assemblyGO:0030031640.014
response to radiationGO:0009314510.014
carbohydrate homeostasisGO:003350010.014
regulation of response to extracellular stimulusGO:003210410.014
sensory system developmentGO:0048880760.014
regulation of programmed cell deathGO:00430671010.014
gastrulationGO:00073692080.014
cellular carbohydrate metabolic processGO:004426240.014
ubiquitin dependent protein catabolic processGO:000651130.014
cellular response to dna damage stimulusGO:0006974240.014
actin mediated cell contractionGO:007025210.014
cellular response to lipopolysaccharideGO:007122230.014
development of primary female sexual characteristicsGO:004654540.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
regulation of tube sizeGO:003515020.014
positive regulation of biosynthetic processGO:0009891680.014
cell cycleGO:0007049930.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
connective tissue developmentGO:0061448990.013
negative regulation of immune responseGO:005077720.013
striated muscle cell developmentGO:00550021080.013
blood circulationGO:0008015870.013
regulation of circadian rhythmGO:004275240.013
ovulation cycle processGO:002260220.013
cell morphogenesisGO:00009022890.013
response to glucoseGO:000974930.013
reproductive processGO:0022414400.013
pigmentationGO:0043473850.013
epithelial tube morphogenesisGO:00605621480.013
regulation of cell migrationGO:0030334400.013
smooth muscle contractionGO:000693920.013
cellular response to extracellular stimulusGO:003166820.013
erk1 and erk2 cascadeGO:007037140.013
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.013
positive regulation of cytokine productionGO:000181920.013
regulation of blood vessel sizeGO:005088020.013
eye photoreceptor cell developmentGO:0042462300.013
actin cytoskeleton organizationGO:0030036630.013
response to woundingGO:00096111160.013
negative regulation of synapse assemblyGO:005196420.013
sex determinationGO:000753010.013
developmental programmed cell deathGO:001062340.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
regulation of jak stat cascadeGO:004642530.013
embryonic heart tube developmentGO:00350501330.013
tissue remodelingGO:004877140.013
positive regulation of cellular carbohydrate metabolic processGO:001067610.013
cellular response to radiationGO:007147840.012
somatic stem cell maintenanceGO:003501910.012
positive regulation of epithelial cell migrationGO:001063420.012
mitochondrion organizationGO:000700540.012
convergent extensionGO:00600261180.012
cell morphogenesis involved in differentiationGO:00009041950.012
sprouting angiogenesisGO:0002040530.012
cell adhesion mediated by integrinGO:003362710.012
reactive oxygen species metabolic processGO:007259360.012
macrophage chemotaxisGO:004824630.012
nucleoside monophosphate catabolic processGO:000912540.012
epithelial cell morphogenesisGO:000338220.012
response to hormoneGO:0009725480.012
positive regulation of lipid metabolic processGO:004583410.012
cell substrate adhesionGO:003158940.012
negative regulation of protein phosphorylationGO:000193340.012
intracellular transportGO:0046907320.012
calcium mediated signalingGO:001972220.012
single organism membrane fusionGO:004480120.012
positive regulation of cell communicationGO:0010647560.012
myeloid cell differentiationGO:0030099860.012
regulation of neurogenesisGO:0050767870.012
positive regulation of protein complex assemblyGO:003133420.012
cell matrix adhesionGO:000716040.012
fin developmentGO:0033333770.012
regulation of cell substrate adhesionGO:001081010.012
chordate embryonic developmentGO:00430092710.012
positive regulation of cell proliferationGO:0008284150.011
positive regulation of rna biosynthetic processGO:1902680570.011
negative regulation of protein complex assemblyGO:003133310.011
myeloid cell developmentGO:0061515320.011
microtubule based processGO:0007017600.011
regulation of wnt signaling pathwayGO:0030111530.011
blood vessel endothelial cell migrationGO:0043534180.011
regulation of stem cell differentiationGO:200073640.011
positive regulation of gene expressionGO:0010628710.011
superoxide metabolic processGO:000680120.011
endothelial cell migrationGO:0043542190.011
establishment of localization in cellGO:0051649770.011
protein secretionGO:000930610.011
protein localizationGO:0008104400.011
positive regulation of cell adhesionGO:004578510.011
positive regulation of dna metabolic processGO:005105410.011
anterior posterior pattern specificationGO:00099521520.011
negative regulation of kinase activityGO:003367340.011
regulation of cell developmentGO:00602841000.011
pigment granule localizationGO:0051875250.011
cellular response to stressGO:0033554620.011
lymphangiogenesisGO:0001946250.011
embryonic hemopoiesisGO:0035162530.011
positive regulation of molecular functionGO:0044093330.011
positive regulation of cell divisionGO:005178120.011
regulation of glial cell differentiationGO:004568540.011
neurotransmitter transportGO:000683620.011
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
cellular response to endogenous stimulusGO:0071495680.011
cellular response to hypoxiaGO:007145610.011

cdkn1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.057
nervous system diseaseDOID:86300.026
immune system diseaseDOID:291400.019
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
disease of metabolismDOID:001466700.015
organ system cancerDOID:005068600.014
musculoskeletal system diseaseDOID:1700.013
hematopoietic system diseaseDOID:7400.013