Danio rerio

0 known processes

trim8

tripartite motif-containing 8

(Aliases: si:ch211-208d15.5,wu:fc90g07,fc90g07)

trim8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immune system processGO:00023762410.432
larval developmentGO:000216420.340
nucleic acid metabolic processGO:00903042440.309
signal transductionGO:00071654550.307
heterocycle biosynthetic processGO:00181302150.291
embryonic organ developmentGO:00485683810.274
multicellular organism growthGO:003526440.235
regulation of multicellular organism growthGO:004001440.231
negative regulation of biological processGO:00485193040.208
regulation of cell differentiationGO:00455951420.207
regulation of biological qualityGO:00650082630.191
cellular nitrogen compound metabolic processGO:00346412900.185
lipid storageGO:001991510.170
regulation of cellular metabolic processGO:00313233200.169
nitrogen compound metabolic processGO:00068073190.164
protein metabolic processGO:00195381830.158
response to chemicalGO:00422213200.157
cellular macromolecule metabolic processGO:00442603910.141
cell surface receptor signaling pathwayGO:00071663250.141
transcription dna templatedGO:00063511810.137
regulation of primary metabolic processGO:00800903110.136
negative regulation of signal transductionGO:0009968940.132
regulation of transcription dna templatedGO:00063552130.131
olfactory lobe developmentGO:002198840.126
central nervous system developmentGO:00074173870.123
cellular component movementGO:00069283350.120
negative regulation of cellular processGO:00485232830.118
hematopoietic or lymphoid organ developmentGO:00485341910.117
cellular protein metabolic processGO:00442671290.116
generation of neuronsGO:00486993850.114
organic substance biosynthetic processGO:19015762890.111
regulation of multicellular organismal developmentGO:20000262230.108
nucleobase containing compound biosynthetic processGO:00346542050.105
aromatic compound biosynthetic processGO:00194382170.098
regulation of multicellular organismal processGO:00512392770.097
regulation of developmental processGO:00507932470.097
gene expressionGO:00104672520.096
protein modification processGO:00362111000.092
maintenance of locationGO:005123540.092
negative regulation of synapse assemblyGO:005196420.091
positive regulation of cellular processGO:00485222010.088
cellular aromatic compound metabolic processGO:00067252950.086
agingGO:000756820.084
myeloid cell differentiationGO:0030099860.083
regulation of neurogenesisGO:0050767870.083
regulation of nucleic acid templated transcriptionGO:19035062130.082
organic cyclic compound biosynthetic processGO:19013622230.081
regulation of metabolic processGO:00192223590.080
cellular component biogenesisGO:00440851780.079
vasculature developmentGO:00019442780.078
heterocycle metabolic processGO:00464832900.076
single organism localizationGO:19025782250.075
regulation of nitrogen compound metabolic processGO:00511712510.073
cellular macromolecule biosynthetic processGO:00346452240.072
neuron differentiationGO:00301823530.072
regulation of rna metabolic processGO:00512522240.072
single organism organelle organizationGO:19025891990.071
meiotic nuclear divisionGO:000712640.069
cellular protein modification processGO:00064641000.069
olfactory bulb developmentGO:002177240.068
negative regulation of metabolic processGO:0009892860.068
regulation of cellular protein metabolic processGO:0032268520.068
biosynthetic processGO:00090582940.066
locomotor rhythmGO:004547530.064
skeletal system developmentGO:00015011810.064
cell motilityGO:00488702440.064
rna metabolic processGO:00160702190.063
regulation of biosynthetic processGO:00098892500.063
regulation of dendrite developmentGO:005077330.062
negative regulation of cellular metabolic processGO:0031324770.060
single organism metabolic processGO:00447102170.060
regulation of peptidyl tyrosine phosphorylationGO:005073010.059
startle responseGO:000196440.059
regulation of cellular amino acid metabolic processGO:000652100.058
cell morphogenesis involved in differentiationGO:00009041950.058
cellular biosynthetic processGO:00442492860.057
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.057
establishment of protein localization to organelleGO:007259440.056
cellular nitrogen compound biosynthetic processGO:00442712180.056
regulation of rna biosynthetic processGO:20011412130.055
forebrain developmentGO:0030900960.055
regulation of macromolecule metabolic processGO:00602553170.054
localization of cellGO:00516742440.053
negative regulation of protein phosphorylationGO:000193340.052
regulation of receptor activityGO:001046920.052
negative regulation of cell communicationGO:0010648960.051
positive regulation of cell cycleGO:004578730.051
regulation of nucleobase containing compound metabolic processGO:00192192500.050
growthGO:00400071740.050
positive regulation of multicellular organismal processGO:0051240520.049
regulation of cell deathGO:00109411030.049
negative regulation of macromolecule metabolic processGO:0010605760.049
female gonad developmentGO:000858540.049
positive regulation of catabolic processGO:000989640.048
regulation of gene expressionGO:00104682650.048
morphogenesis of an epitheliumGO:00020093330.048
blood vessel developmentGO:00015682460.047
negative regulation of cytokine mediated signaling pathwayGO:000196020.047
cell morphogenesis involved in neuron differentiationGO:00486671630.046
regulation of programmed cell deathGO:00430671010.046
cellular component morphogenesisGO:00329893360.046
regulation of nervous system developmentGO:0051960900.046
cellular ketone metabolic processGO:0042180110.046
regulation of response to stimulusGO:00485832690.045
locomotionGO:00400113130.045
embryonic cranial skeleton morphogenesisGO:0048701900.044
immune system developmentGO:00025201910.044
brain developmentGO:00074202930.044
head developmentGO:00603223030.044
multi organism processGO:00517041340.044
cell substrate adhesionGO:003158940.043
thermosensory behaviorGO:004004010.043
macromolecule modificationGO:00434121110.043
lamellipodium organizationGO:009758110.043
nucleic acid templated transcriptionGO:00976591810.043
pigment cell differentiationGO:0050931380.042
cellular component assemblyGO:00226071700.042
neuron developmentGO:00486662620.042
regulation of dendrite morphogenesisGO:004881430.042
taxisGO:00423301090.041
negative regulation of nucleobase containing compound metabolic processGO:0045934590.041
cell projection assemblyGO:0030031640.041
rna biosynthetic processGO:00327741810.041
regulation of nucleocytoplasmic transportGO:004682220.040
regulation of macromolecule biosynthetic processGO:00105562250.040
hemopoiesisGO:00300971830.040
regulation of cell developmentGO:00602841000.040
response to external stimulusGO:00096052640.039
regulation of signal transductionGO:00099662250.038
protein stabilizationGO:005082120.038
regulation of cellular biosynthetic processGO:00313262450.037
regulation of cellular ketone metabolic processGO:001056570.037
axon guidanceGO:0007411860.037
regulation of cellular response to growth factor stimulusGO:0090287350.036
stem cell developmentGO:0048864820.035
nucleobase containing compound metabolic processGO:00061392740.035
regulation of protein localization to nucleusGO:190018020.035
forebrain cell migrationGO:002188510.034
digestive tract morphogenesisGO:00485462310.034
positive regulation of response to stimulusGO:0048584800.034
neuron neuron synaptic transmissionGO:000727010.033
cell migrationGO:00164772370.033
entrainment of circadian clockGO:000964920.033
modification dependent protein catabolic processGO:001994130.033
establishment of localization in cellGO:0051649770.033
development of primary female sexual characteristicsGO:004654540.033
eye developmentGO:00016542770.033
nuclear transportGO:005116940.033
cognitionGO:005089010.033
homeostatic processGO:00425921420.033
protein demethylationGO:000648220.033
synaptic growth at neuromuscular junctionGO:005112420.032
neuron projection guidanceGO:0097485860.032
axonogenesisGO:00074091520.032
cell projection morphogenesisGO:00488582440.032
negative regulation of signalingGO:0023057960.032
regulation of cell communicationGO:00106462320.032
organic cyclic compound metabolic processGO:19013603010.031
regulation of cellular amine metabolic processGO:003323800.031
negative regulation of response to stimulusGO:00485851040.030
regulation of circadian rhythmGO:004275240.030
chemotaxisGO:00069351040.030
forebrain anterior posterior pattern specificationGO:002179730.030
cilium organizationGO:0044782710.029
negative regulation of cell developmentGO:0010721260.029
erythrocyte differentiationGO:0030218540.029
circadian rhythmGO:0007623190.029
regulation of cellular macromolecule biosynthetic processGO:20001122220.029
muscle structure developmentGO:00610611960.029
macromolecule biosynthetic processGO:00090592270.029
positive regulation of map kinase activityGO:004340630.029
negative regulation of gene expressionGO:0010629650.028
axon midline choice point recognitionGO:001619940.028
sleepGO:003043110.028
regulation of protein complex assemblyGO:004325430.028
regulation of protein targetingGO:190353320.028
cellular amino acid metabolic processGO:000652070.028
positive regulation of biosynthetic processGO:0009891680.028
determination of bilateral symmetryGO:00098552040.028
cardiac cell fate commitmentGO:006091110.028
cell part morphogenesisGO:00329902460.027
regulation of protein catabolic processGO:004217610.027
regulation of biomineral tissue developmentGO:007016720.027
positive regulation of biological processGO:00485182530.027
nucleocytoplasmic transportGO:000691340.027
outflow tract morphogenesisGO:000315110.027
extrinsic apoptotic signaling pathwayGO:009719130.027
neuromuscular process controlling balanceGO:005088530.027
negative regulation of protein transportGO:005122430.027
cell morphogenesisGO:00009022890.027
positive regulation of cell adhesionGO:004578510.027
establishment of localizationGO:00512342440.026
regulation of cell substrate adhesionGO:001081010.026
carbohydrate homeostasisGO:003350010.025
rna localizationGO:000640340.025
regulation of protein import into nucleusGO:004230620.025
protein localization to nucleusGO:003450430.025
regionalizationGO:00030022740.025
negative regulation of nitrogen compound metabolic processGO:0051172590.025
regulation of intracellular signal transductionGO:1902531570.025
lamellipodium assemblyGO:003003210.024
regulation of synapse assemblyGO:005196330.024
enzyme linked receptor protein signaling pathwayGO:00071671060.024
regulation of signalingGO:00230512350.024
regulation of protein modification by small protein conjugation or removalGO:190332030.024
embryonic skeletal system developmentGO:0048706970.024
leukocyte proliferationGO:007066110.024
organic acid metabolic processGO:0006082310.024
negative regulation of kinase activityGO:003367340.024
cell projection organizationGO:00300302840.024
sensory organ morphogenesisGO:00905962000.024
positive regulation of cell substrate adhesionGO:001081110.023
myeloid cell homeostasisGO:0002262560.023
organelle assemblyGO:00709251100.023
positive regulation of apoptotic signaling pathwayGO:200123510.023
response to organic substanceGO:00100331530.023
negative regulation of protein kinase activityGO:000646940.023
zymogen activationGO:003163830.023
regulation of reactive oxygen species metabolic processGO:200037720.023
cell fate specificationGO:0001708680.023
positive regulation of cell communicationGO:0010647560.022
erk1 and erk2 cascadeGO:007037140.022
mesenchyme developmentGO:00604851270.022
axon developmentGO:00615641660.022
negative regulation of axon extension involved in axon guidanceGO:004884310.022
negative regulation of catabolic processGO:000989530.022
negative regulation of mapk cascadeGO:004340940.022
positive regulation of developmental processGO:0051094500.021
regulation of protein metabolic processGO:0051246560.021
nuclear importGO:005117030.021
central nervous system neuron axonogenesisGO:0021955180.021
ubiquitin dependent protein catabolic processGO:000651130.021
single organism nuclear importGO:190259330.021
actin polymerization or depolymerizationGO:000815420.021
regulation of cell shapeGO:000836010.021
synaptic vesicle localizationGO:009747910.021
protein dephosphorylationGO:000647030.021
carboxylic acid metabolic processGO:0019752220.021
membrane invaginationGO:001032410.020
heart developmentGO:00075073130.020
organic substance transportGO:0071702580.020
positive regulation of cellular catabolic processGO:003133130.020
positive regulation of epithelial cell differentiationGO:003085820.020
regulation of autophagyGO:001050630.020
regulation of phosphorylationGO:0042325260.020
sensory organ developmentGO:00074233930.020
positive regulation of cell differentiationGO:0045597300.020
neuron projection developmentGO:00311751800.020
neuroepithelial cell differentiationGO:0060563260.020
positive regulation of gene expressionGO:0010628710.020
telencephalon developmentGO:0021537140.020
cellular protein catabolic processGO:004425740.020
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.020
neuron projection morphogenesisGO:00488121610.020
adult behaviorGO:003053420.019
regulation of sodium ion transportGO:000202820.019
stem cell maintenanceGO:001982740.019
cytoskeleton organizationGO:0007010960.019
negative regulation of chemotaxisGO:005092240.019
protein targeting to nucleusGO:004474430.019
regulation of erk1 and erk2 cascadeGO:007037240.019
response to carbohydrateGO:000974330.019
developmental growthGO:00485891660.019
negative regulation of programmed cell deathGO:0043069580.019
embryonic organ morphogenesisGO:00485622740.019
cellular macromolecular complex assemblyGO:0034622240.019
erythrocyte homeostasisGO:0034101550.019
positive regulation of rna metabolic processGO:0051254590.019
oxoacid metabolic processGO:0043436310.019
protein localizationGO:0008104400.019
regulation of bindingGO:005109830.019
regulation of cytoplasmic transportGO:190364940.019
positive regulation of transcription dna templatedGO:0045893570.018
system processGO:00030081850.018
cellular amine metabolic processGO:004410620.018
negative regulation of gliogenesisGO:001401410.018
synaptic target recognitionGO:000803910.018
positive regulation of small gtpase mediated signal transductionGO:005105710.018
deathGO:00162651210.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.018
chemosensory behaviorGO:000763510.018
organelle organizationGO:00069962270.018
regulation of stem cell differentiationGO:200073640.018
protein secretionGO:000930610.018
peptidyl serine phosphorylationGO:001810510.018
embryonic skeletal system morphogenesisGO:0048704930.018
hatchingGO:003518840.018
transcription from rna polymerase ii promoterGO:0006366800.018
transportGO:00068102200.017
heart loopingGO:0001947940.017
regulation of cell activationGO:005086510.017
nucleic acid transportGO:005065720.017
negative regulation of multicellular organismal processGO:0051241690.017
negative regulation of developmental processGO:0051093650.017
response to alkaloidGO:004327920.017
blood vessel morphogenesisGO:00485142160.017
commissural neuron axon guidanceGO:007167930.017
cellular modified amino acid metabolic processGO:000657530.017
compound eye developmentGO:004874920.017
epithelial to mesenchymal transitionGO:0001837210.017
cellular response to growth factor stimulusGO:0071363390.017
protein polymerizationGO:005125840.017
mitotic cell cycle embryonicGO:004544820.017
positive regulation of ras protein signal transductionGO:004657910.016
insulin like growth factor receptor signaling pathwayGO:004800940.016
embryonic pattern specificationGO:0009880440.016
specification of symmetryGO:00097992040.016
negative regulation of nucleocytoplasmic transportGO:004682320.016
meiotic cell cycle processGO:190304630.016
programmed cell deathGO:00125011190.016
regulation of cytokine productionGO:000181730.016
response to hexoseGO:000974630.016
connective tissue developmentGO:0061448990.016
neurological system processGO:0050877620.016
peptidyl serine modificationGO:001820920.016
glucose homeostasisGO:004259310.016
positive regulation of cellular metabolic processGO:0031325940.016
regulation of protein transportGO:005122330.016
small gtpase mediated signal transductionGO:000726480.016
protein importGO:001703830.016
female sex differentiationGO:004666040.016
lymphocyte proliferationGO:004665110.016
positive regulation of protein complex assemblyGO:003133420.016
positive regulation of nucleobase containing compound metabolic processGO:0045935690.015
stem cell differentiationGO:00488631170.015
proteolysis involved in cellular protein catabolic processGO:005160330.015
central nervous system neuron developmentGO:0021954290.015
cellular response to endogenous stimulusGO:0071495680.015
symbiosis encompassing mutualism through parasitismGO:004440340.015
digestive system developmentGO:00551232890.015
urogenital system developmentGO:0001655970.015
modification dependent macromolecule catabolic processGO:004363230.015
negative regulation of cytoplasmic transportGO:190365020.015
positive regulation of cell activationGO:005086710.015
peripheral nervous system developmentGO:0007422550.015
regulation of reproductive processGO:200024140.015
negative regulation of cell deathGO:0060548600.015
response to drugGO:004249330.015
regulation of membrane potentialGO:0042391230.015
wnt signaling pathwayGO:0016055800.015
female meiotic divisionGO:000714320.015
positive regulation of cytoskeleton organizationGO:005149530.015
positive regulation of cellular biosynthetic processGO:0031328680.014
golgi vesicle transportGO:004819330.014
cell deathGO:00082191210.014
regulation of transcription from rna polymerase ii promoterGO:00063571140.014
lipid metabolic processGO:0006629520.014
response to stressGO:00069502630.014
microtubule based processGO:0007017600.014
response to glucoseGO:000974930.014
regulation of neuron differentiationGO:0045664560.014
autophagyGO:000691440.014
mesenchymal cell differentiationGO:0048762870.014
positive regulation of protein polymerizationGO:003227320.014
peptide transportGO:001583310.014
action potentialGO:0001508190.014
regulation of establishment of protein localizationGO:007020140.014
regulation of cellular component organizationGO:0051128860.014
positive regulation of macromolecule metabolic processGO:0010604930.014
proteasomal protein catabolic processGO:001049820.014
small molecule metabolic processGO:0044281770.014
protein import into nucleusGO:000660630.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
regulation of apoptotic processGO:0042981980.014
homeostasis of number of cellsGO:0048872620.014
macromolecular complex subunit organizationGO:0043933740.013
somatic stem cell maintenanceGO:003501910.013
regulation of synapse organizationGO:005080730.013
hormone secretionGO:004687920.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
phagocytosisGO:000690930.013
multicellular organismal response to stressGO:003355520.013
negative regulation of intracellular transportGO:003238730.013
regulation of dna recombinationGO:000001820.013
mesoderm developmentGO:0007498880.013
protein polyubiquitinationGO:000020940.013
cellular response to organic substanceGO:00713101050.013
regulation of mrna processingGO:005068430.013
negative regulation of neurogenesisGO:0050768200.013
cartilage developmentGO:0051216960.013
regulation of cellular protein catabolic processGO:190336210.013
ameboidal type cell migrationGO:00016671430.013
transmission of nerve impulseGO:0019226190.013
developmental pigmentationGO:0048066480.013
cell matrix adhesionGO:000716040.013
embryonic heart tube developmentGO:00350501330.013
regulation of neurological system processGO:003164420.013
glutamate receptor signaling pathwayGO:000721510.012
phosphate containing compound metabolic processGO:00067961080.012
phagocytosis engulfmentGO:000691110.012
establishment of synaptic vesicle localizationGO:009748010.012
photoreceptor cell morphogenesisGO:000859410.012
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.012
negative regulation of cell differentiationGO:0045596460.012
response to monosaccharideGO:003428430.012
amine metabolic processGO:000930820.012
apoptotic processGO:00069151160.012
germ line stem cell maintenanceGO:003071820.012
positive regulation of multi organism processGO:004390230.012
negative regulation of nucleic acid templated transcriptionGO:1903507450.012
hormone transportGO:000991420.012
multi organism cellular processGO:004476420.012
regulation of intracellular protein transportGO:003315730.012
negative regulation of macromolecule biosynthetic processGO:0010558480.012
regulation of melanocyte differentiationGO:004563420.012
immune responseGO:0006955280.012
tube morphogenesisGO:00352393490.012
phosphorus metabolic processGO:00067931090.012
cellular component assembly involved in morphogenesisGO:00109271070.012
positive regulation of signal transductionGO:0009967560.012
neuron remodelingGO:001632210.012
cell proliferationGO:0008283800.012
epithelial cell differentiationGO:00308551160.012
renal system developmentGO:0072001940.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
neural crest formationGO:0014029140.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
regulation of transmembrane transporter activityGO:002289820.011
negative chemotaxisGO:005091910.011
peptidyl threonine modificationGO:001821010.011
cellular response to extracellular stimulusGO:003166820.011
negative regulation of apoptotic processGO:0043066550.011
notch signaling pathwayGO:0007219350.011
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.011
regulation of cell projection assemblyGO:006049140.011
regulation of developmental growthGO:0048638380.011
nuclear migrationGO:000709730.011
regulation of postsynaptic membrane potentialGO:006007810.011
dna templated transcription elongationGO:000635430.011
organelle localizationGO:0051640490.011
tissue remodelingGO:004877140.011
embryonic heart tube morphogenesisGO:00031431080.011
cell cycleGO:0007049930.011
cytokinesisGO:000091030.011
columnar cuboidal epithelial cell differentiationGO:0002065380.011
lipid catabolic processGO:001604240.011
cellular localizationGO:0051641970.011
positive regulation of leukocyte differentiationGO:190210710.011
response to external biotic stimulusGO:0043207970.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
interspecies interaction between organismsGO:004441940.011
regulation of protein polymerizationGO:003227120.011
negative regulation of protein localization to nucleusGO:190018120.011
central nervous system neuron differentiationGO:0021953740.011
positive regulation of nucleic acid templated transcriptionGO:1903508570.011
negative regulation of cellular protein metabolic processGO:0032269160.011
locomotory behaviorGO:0007626340.011
negative regulation of rna biosynthetic processGO:1902679450.011
pigmentationGO:0043473850.011
regulation of extrinsic apoptotic signaling pathwayGO:200123630.011
spermatid differentiationGO:004851520.011
cell cycle g1 s phase transitionGO:004484310.011
inner ear morphogenesisGO:0042472630.011
response to growth factorGO:0070848390.011
nucleobase containing compound transportGO:001593120.011
endosomal transportGO:001619720.011
rna processingGO:0006396250.011
ovulation cycleGO:004269820.011
regulation of protein bindingGO:004339330.010
negative regulation of protein serine threonine kinase activityGO:007190120.010
response to biotic stimulusGO:0009607970.010
response to woundingGO:00096111160.010
meiotic chromosome segregationGO:004513230.010
behaviorGO:0007610740.010
production of molecular mediator of immune responseGO:000244020.010
positive regulation of canonical wnt signaling pathwayGO:009026340.010
signal transduction by phosphorylationGO:0023014180.010
negative regulation of nervous system developmentGO:0051961220.010
negative regulation of defense responseGO:003134820.010
striated muscle tissue developmentGO:00147061100.010
viral processGO:001603210.010
positive regulation of gliogenesisGO:001401520.010
positive regulation of mrna metabolic processGO:190331320.010
protein localization to plasma membraneGO:007265910.010
melanin metabolic processGO:000658220.010
g1 s transition of mitotic cell cycleGO:000008210.010
skeletal system morphogenesisGO:00487051020.010
negative regulation of cytokine productionGO:000181810.010
lipid localizationGO:0010876110.010
negative regulation of protein metabolic processGO:0051248160.010

trim8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.041
nervous system diseaseDOID:86300.039
disease of cellular proliferationDOID:1456600.016
disease of metabolismDOID:001466700.015
cancerDOID:16200.014