Danio rerio

0 known processes

ucp2

uncoupling protein 2

(Aliases: MGC76853,cb74,MGC65762)

ucp2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
system processGO:00030081850.296
cellular response to nutrient levelsGO:003166920.195
Rat
response to organic substanceGO:00100331530.188
Zebrafish Rat
organic acid metabolic processGO:0006082310.140
organonitrogen compound metabolic processGO:1901564740.138
carboxylic acid metabolic processGO:0019752220.135
regulation of response to oxidative stressGO:190288220.130
multicellular organismal macromolecule metabolic processGO:004425920.117
response to glucocorticoidGO:005138410.108
cellular response to external stimulusGO:007149620.106
Rat
collagen metabolic processGO:003296320.104
small molecule metabolic processGO:0044281770.101
immune system processGO:00023762410.094
multicellular organismal metabolic processGO:004423620.084
sphingolipid biosynthetic processGO:003014820.083
cellular response to starvationGO:000926710.080
Rat
oxoacid metabolic processGO:0043436310.078
nuclear importGO:005117030.077
response to corticosteroidGO:003196010.077
agingGO:000756820.077
Rat
response to endogenous stimulusGO:0009719830.077
Zebrafish Rat
larval developmentGO:000216420.075
response to carbohydrateGO:000974330.071
Rat
blood vessel developmentGO:00015682460.069
cell surface receptor signaling pathwayGO:00071663250.066
adult behaviorGO:003053420.066
establishment of protein localization to organelleGO:007259440.065
protein targeting to nucleusGO:004474430.064
cellular response to extracellular stimulusGO:003166820.064
Rat
regulation of cellular response to oxidative stressGO:190040720.064
positive regulation of transportGO:005105020.060
response to drugGO:004249330.060
single organism organelle organizationGO:19025891990.059
single organism localizationGO:19025782250.058
Rat
mitochondrion organizationGO:000700540.058
cellular response to chemical stimulusGO:00708871570.055
Zebrafish Rat
cell death in response to oxidative stressGO:003647320.055
single organism metabolic processGO:00447102170.053
response to organic cyclic compoundGO:0014070510.051
Zebrafish
regulation of epithelial cell proliferationGO:005067830.051
response to monosaccharideGO:003428430.050
Rat
protein import into nucleusGO:000660630.049
negative regulation of biological processGO:00485193040.048
Rat
regulation of cellular ketone metabolic processGO:001056570.047
nuclear transportGO:005116940.046
nucleocytoplasmic transportGO:000691340.044
autophagyGO:000691440.044
regulation of multicellular organism growthGO:004001440.044
response to steroid hormoneGO:0048545350.044
Zebrafish
cognitionGO:005089010.044
catabolic processGO:0009056320.042
response to hexoseGO:000974630.041
Rat
membrane lipid biosynthetic processGO:004646720.040
regulation of nucleotide catabolic processGO:003081120.040
single organism biosynthetic processGO:0044711710.039
single organism nuclear importGO:190259330.039
cofactor metabolic processGO:0051186150.039
regulation of cellular amino acid metabolic processGO:000652100.038
response to stressGO:00069502630.038
Rat
regulation of protein transportGO:005122330.038
response to hormoneGO:0009725480.037
Zebrafish Rat
cellular amino acid metabolic processGO:000652070.037
regulation of cytokine productionGO:000181730.037
regulation of carbohydrate metabolic processGO:000610940.036
cell migrationGO:00164772370.036
response to transition metal nanoparticleGO:1990267280.035
cellular component movementGO:00069283350.035
response to alkaloidGO:004327920.035
cell substrate adhesionGO:003158940.034
regulation of heart growthGO:006042020.032
cellular carbohydrate metabolic processGO:004426240.032
cellular response to organic substanceGO:00713101050.032
Zebrafish Rat
response to biotic stimulusGO:0009607970.031
regulation of establishment of protein localizationGO:007020140.031
nucleoside monophosphate catabolic processGO:000912540.031
biosynthetic processGO:00090582940.031
hydrogen peroxide metabolic processGO:004274320.029
response to ketoneGO:190165410.029
blood vessel morphogenesisGO:00485142160.029
response to nutrientGO:000758430.028
locomotionGO:00400113130.028
protein importGO:001703830.028
multi organism processGO:00517041340.028
Rat
positive regulation of catabolic processGO:000989640.028
regulation of system processGO:0044057400.027
carbohydrate derivative metabolic processGO:1901135610.027
protein localization to nucleusGO:003450430.027
regulation of muscle contractionGO:000693730.027
regulation of metal ion transportGO:001095940.026
multicellular organism growthGO:003526440.026
response to lipidGO:0033993600.026
Zebrafish Rat
cellular macromolecule metabolic processGO:00442603910.026
regulation of production of molecular mediator of immune responseGO:000270010.026
gtp metabolic processGO:004603940.025
heart contractionGO:0060047710.025
regulation of bone mineralizationGO:003050020.025
guanosine containing compound metabolic processGO:190106840.025
cellular response to oxygen levelsGO:007145310.025
response to external stimulusGO:00096052640.024
Rat
negative regulation of heart contractionGO:004582220.024
nitric oxide biosynthetic processGO:000680920.024
regulation of tube sizeGO:003515020.024
regulation of protein complex assemblyGO:004325430.023
cell deathGO:00082191210.022
Rat
ameboidal type cell migrationGO:00016671430.022
carboxylic acid catabolic processGO:004639530.022
alpha amino acid metabolic processGO:190160530.022
deathGO:00162651210.022
Rat
positive regulation of cellular catabolic processGO:003133130.022
organelle organizationGO:00069962270.022
extrinsic apoptotic signaling pathwayGO:009719130.022
cell morphogenesis involved in differentiationGO:00009041950.022
actin filament based processGO:0030029640.022
regulation of protein import into nucleusGO:004230620.022
regulation of cellular carbohydrate metabolic processGO:001067540.022
cellular amine metabolic processGO:004410620.022
protein polymerizationGO:005125840.022
response to mechanical stimulusGO:0009612240.022
microtubule polymerizationGO:004678520.022
cellular biosynthetic processGO:00442492860.021
cellular catabolic processGO:0044248270.021
establishment of localizationGO:00512342440.021
Rat
regionalizationGO:00030022740.021
regulation of gtp catabolic processGO:003312420.021
regulation of blood vessel sizeGO:005088020.021
regulation of cellular component organizationGO:0051128860.021
developmental growthGO:00485891660.020
monovalent inorganic cation transportGO:0015672420.020
centrosome organizationGO:005129710.020
rna localizationGO:000640340.020
regulation of cell shapeGO:000836010.020
apical junction assemblyGO:004329710.020
negative regulation of striated muscle tissue developmentGO:004584320.020
positive regulation of cellular amino acid metabolic processGO:004576400.019
cell migration involved in gastrulationGO:0042074790.019
single organism cellular localizationGO:1902580460.019
positive regulation of i kappab kinase nf kappab signalingGO:004312330.019
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.019
transportGO:00068102200.019
Rat
modulation by virus of host morphology or physiologyGO:001904810.019
protein heterooligomerizationGO:005129110.019
cellular component disassemblyGO:002241110.019
fat soluble vitamin metabolic processGO:000677540.019
nucleobase containing compound biosynthetic processGO:00346542050.018
regulation of purine nucleotide catabolic processGO:003312120.018
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217520.018
regulation of protein localization to nucleusGO:190018020.018
signal transductionGO:00071654550.018
regulation of transporter activityGO:003240920.018
response to chemicalGO:00422213200.018
Zebrafish Rat
amine metabolic processGO:000930820.018
microtubule organizing center organizationGO:003102310.018
s adenosylmethionine metabolic processGO:004650010.018
regulation of membrane potentialGO:0042391230.018
Mouse
regulation of oxidative stress induced cell deathGO:190320120.018
response to bacteriumGO:0009617580.017
regulation of gtpase activityGO:004308720.017
cellular lipid metabolic processGO:0044255360.017
vasculature developmentGO:00019442780.017
cellular component biogenesisGO:00440851780.017
regulation of response to nutrient levelsGO:003210710.017
positive regulation of purine nucleotide catabolic processGO:003312310.017
regulation of protein polymerizationGO:003227120.017
negative regulation of feeding behaviorGO:200025220.017
negative regulation of signal transduction in absence of ligandGO:190109910.017
cellular ketone metabolic processGO:0042180110.017
regulation of glucose importGO:004632410.017
regulation of transmembrane transporter activityGO:002289820.016
circadian sleep wake cycle sleepGO:005080210.016
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.016
negative regulation of small gtpase mediated signal transductionGO:005105810.016
phosphorylationGO:0016310690.016
regulation of cytokine biosynthetic processGO:004203510.016
regulation of actin filament based processGO:003297090.016
cellular component morphogenesisGO:00329893360.016
protein complex disassemblyGO:004324110.016
inorganic anion transportGO:0015698250.016
regulation of nucleocytoplasmic transportGO:004682220.016
positive regulation of epithelial cell proliferationGO:005067910.016
response to other organismGO:0051707970.016
positive regulation of developmental processGO:0051094500.015
regulation of cellular metabolic processGO:00313233200.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015
negative regulation of muscle tissue developmentGO:190186220.015
response to nitrogen compoundGO:1901698190.015
Rat
regulation of protein bindingGO:004339330.015
posterior lateral line system developmentGO:0048915460.015
response to dexamethasoneGO:007154810.015
regulation of dendrite developmentGO:005077330.015
gastrulationGO:00073692080.015
maintenance of locationGO:005123540.015
establishment of rna localizationGO:005123630.015
response to oxygen containing compoundGO:1901700550.015
Rat
cellular response to hormone stimulusGO:0032870390.015
Zebrafish Rat
positive regulation of cellular component biogenesisGO:004408930.015
chloride transmembrane transportGO:190247640.015
positive regulation of cytokine productionGO:000181920.015
establishment of protein localization to plasma membraneGO:009000210.015
cellular response to endogenous stimulusGO:0071495680.015
Zebrafish Rat
positive regulation of secretion by cellGO:190353210.015
protein activation cascadeGO:007237660.015
superoxide metabolic processGO:000680120.015
b cell mediated immunityGO:001972430.014
gtp catabolic processGO:000618420.014
angiogenesisGO:00015251580.014
cellular response to hypoxiaGO:007145610.014
cellular response to steroid hormone stimulusGO:0071383310.014
Zebrafish
immunoglobulin mediated immune responseGO:001606430.014
negative regulation of epithelial cell proliferationGO:005068010.014
response to amino acidGO:004320020.014
positive regulation of cellular amine metabolic processGO:003324000.014
xenobiotic metabolic processGO:000680540.014
b cell activationGO:004211320.014
positive regulation of cytoskeleton organizationGO:005149530.014
organic substance biosynthetic processGO:19015762890.014
cellular component assembly involved in morphogenesisGO:00109271070.014
ion transmembrane transportGO:0034220910.014
cellular response to decreased oxygen levelsGO:003629410.014
cellular response to organic cyclic compoundGO:0071407380.014
Zebrafish
macromolecular complex subunit organizationGO:0043933740.014
response to fluid shear stressGO:003440520.013
response to glucoseGO:000974930.013
Rat
regulation of macromolecule metabolic processGO:00602553170.013
response to cadmium ionGO:0046686140.013
ribonucleoside monophosphate catabolic processGO:000915840.013
oxidation reduction processGO:0055114410.013
actin polymerization or depolymerizationGO:000815420.013
regulation of intracellular protein transportGO:003315730.013
actin filament based movementGO:003004810.013
cell motilityGO:00488702440.013
production of molecular mediator of immune responseGO:000244020.013
protein metabolic processGO:00195381830.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
sensory perception of smellGO:000760820.013
growthGO:00400071740.013
regulation of circadian sleep wake cycleGO:004274910.013
toxin transportGO:190199820.013
negative regulation of protein phosphorylationGO:000193340.013
mitochondrial transportGO:000683920.013
Rat
positive regulation of gtp catabolic processGO:003312610.013
negative regulation of response to stimulusGO:00485851040.013
Rat
membrane hyperpolarizationGO:006008110.013
gene expressionGO:00104672520.013
positive regulation of cell adhesionGO:004578510.012
regulation of ion transmembrane transporter activityGO:003241220.012
response to estrogenGO:0043627270.012
Zebrafish
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.012
regulation of circadian sleep wake cycle sleepGO:004518710.012
cellular extravasationGO:004512310.012
regulation of cytoskeleton organizationGO:0051493110.012
stem cell differentiationGO:00488631170.012
response to methylmercuryGO:0051597110.012
positive regulation of nucleoside metabolic processGO:004597910.012
long chain fatty acid transportGO:001590910.012
cellular response to lipidGO:0071396390.012
Zebrafish
cellular aldehyde metabolic processGO:000608140.012
regulation of cellular component movementGO:0051270550.012
cellular protein metabolic processGO:00442671290.012
tissue homeostasisGO:0001894250.011
muscle cell migrationGO:001481240.011
regulation of rho protein signal transductionGO:003502320.011
response to external biotic stimulusGO:0043207970.011
regulation of cellular amine metabolic processGO:003323800.011
heart developmentGO:00075073130.011
cell adhesionGO:0007155400.011
positive regulation of nucleotide catabolic processGO:003081310.011
protein modification processGO:00362111000.011
circadian sleep wake cycleGO:004274520.011
metal ion transportGO:0030001580.011
striated muscle contractionGO:0006941120.011
regulation of cytoplasmic transportGO:190364940.011
lymphocyte proliferationGO:004665110.011
negative regulation of signalingGO:0023057960.011
Rat
negative regulation of dna replicationGO:000815620.011
negative regulation of ras protein signal transductionGO:004658010.011
regulation of developmental processGO:00507932470.011
cellular nitrogen compound biosynthetic processGO:00442712180.011
regulation of striated muscle contractionGO:000694220.011
response to oxygen levelsGO:0070482250.010
Rat
glycerol transportGO:001579370.010
regulation of phGO:000688530.010
pyruvate metabolic processGO:000609010.010
regulation of reactive oxygen species metabolic processGO:200037720.010
chloride transportGO:000682180.010
positive regulation of gtpase activityGO:004354710.010
negative regulation of multi organism processGO:004390130.010
aromatic compound biosynthetic processGO:00194382170.010
cellular component assemblyGO:00226071700.010
dicarboxylic acid metabolic processGO:004364810.010

ucp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.029
disease of metabolismDOID:001466700.029
lysosomal storage diseaseDOID:321100.016
hyperinsulinemic hypoglycemiaDOID:1331700.012
carbohydrate metabolic disorderDOID:297800.012