Danio rerio

19 known processes

dkk2

dickkopf homolog 2 (Xenopus laevis)

(Aliases: zgc:171574)

dkk2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of biological processGO:00485193040.343
posterior lateral line system developmentGO:0048915460.281
larval developmentGO:000216420.262
mechanosensory lateral line system developmentGO:0048881490.188
signal transductionGO:00071654550.184
regulation of metabolic processGO:00192223590.184
sensory organ developmentGO:00074233930.168
nitrogen compound metabolic processGO:00068073190.154
cellular macromolecule metabolic processGO:00442603910.141
organic cyclic compound biosynthetic processGO:19013622230.130
regulation of primary metabolic processGO:00800903110.127
regulation of epithelial cell proliferationGO:005067830.126
regulation of nitrogen compound metabolic processGO:00511712510.122
negative regulation of cellular processGO:00485232830.116
sensory system developmentGO:0048880760.114
organic cyclic compound metabolic processGO:19013603010.112
regulation of gene expressionGO:00104682650.111
regulation of macromolecule metabolic processGO:00602553170.107
heterocycle metabolic processGO:00464832900.103
cellular macromolecule biosynthetic processGO:00346452240.089
cellular nitrogen compound metabolic processGO:00346412900.086
rna metabolic processGO:00160702190.086
nucleic acid metabolic processGO:00903042440.086
regulation of cell communicationGO:00106462320.084
immune system developmentGO:00025201910.082
lateral line system developmentGO:0048925760.081
cellular aromatic compound metabolic processGO:00067252950.081
lateral line developmentGO:0048882660.081
gene expressionGO:00104672520.077
posterior lateral line developmentGO:0048916380.072
rna biosynthetic processGO:00327741810.072
cellular nitrogen compound biosynthetic processGO:00442712180.071
single organism metabolic processGO:00447102170.068
generation of neuronsGO:00486993850.066
central nervous system developmentGO:00074173870.065
positive regulation of endothelial cell proliferationGO:000193810.063
response to chemicalGO:00422213200.063
immune system processGO:00023762410.060
transcription dna templatedGO:00063511810.060
regulation of nucleobase containing compound metabolic processGO:00192192500.060
regulation of biological qualityGO:00650082630.058
response to external stimulusGO:00096052640.058
regulation of cellular macromolecule biosynthetic processGO:20001122220.057
macromolecule biosynthetic processGO:00090592270.057
positive regulation of epithelial cell proliferationGO:005067910.057
regulation of response to stimulusGO:00485832690.057
skeletal system developmentGO:00015011810.057
heart developmentGO:00075073130.057
muscle structure developmentGO:00610611960.056
positive regulation of canonical wnt signaling pathwayGO:009026340.055
regulation of biosynthetic processGO:00098892500.053
blood vessel morphogenesisGO:00485142160.053
cartilage developmentGO:0051216960.053
head developmentGO:00603223030.052
organonitrogen compound metabolic processGO:1901564740.052
neuromast developmentGO:0048884460.052
positive regulation of metabolic processGO:00098931080.052
outflow tract morphogenesisGO:000315110.051
extrinsic apoptotic signaling pathwayGO:009719130.050
nucleobase containing compound biosynthetic processGO:00346542050.049
neurotransmitter transportGO:000683620.049
hemopoiesisGO:00300971830.049
cellular component assemblyGO:00226071700.049
vasculature developmentGO:00019442780.048
nucleic acid templated transcriptionGO:00976591810.048
agingGO:000756820.048
regulation of cell differentiationGO:00455951420.047
organic substance biosynthetic processGO:19015762890.047
regulation of macromolecule biosynthetic processGO:00105562250.047
sprouting angiogenesisGO:0002040530.047
negative regulation of multicellular organismal processGO:0051241690.046
negative regulation of cell communicationGO:0010648960.046
biosynthetic processGO:00090582940.045
response to stressGO:00069502630.045
aromatic compound biosynthetic processGO:00194382170.045
phagocytosisGO:000690930.044
regulation of rna metabolic processGO:00512522240.044
regulation of transcription dna templatedGO:00063552130.043
single organism organelle organizationGO:19025891990.043
renal tubule morphogenesisGO:006133310.043
regulation of developmental processGO:00507932470.042
regulation of multicellular organismal developmentGO:20000262230.042
skeletal system morphogenesisGO:00487051020.042
regulation of endothelial cell proliferationGO:000193610.041
nucleobase containing compound metabolic processGO:00061392740.041
nephron epithelium morphogenesisGO:007208810.041
positive regulation of cellular metabolic processGO:0031325940.041
regulation of cellular metabolic processGO:00313233200.040
regulation of stem cell differentiationGO:200073640.040
embryonic skeletal system developmentGO:0048706970.040
camera type eye developmentGO:00430102220.040
stem cell maintenanceGO:001982740.040
neuromast primordium migrationGO:0048883120.040
regulation of cell deathGO:00109411030.039
positive regulation of map kinase activityGO:004340630.039
tube morphogenesisGO:00352393490.039
regulation of reproductive processGO:200024140.038
regulation of synapse organizationGO:005080730.038
positive regulation of nucleic acid templated transcriptionGO:1903508570.038
astrocyte differentiationGO:004870810.038
cell morphogenesis involved in neuron differentiationGO:00486671630.038
blood vessel developmentGO:00015682460.038
synaptic growth at neuromuscular junctionGO:005112420.038
chordate embryonic developmentGO:00430092710.038
specification of symmetryGO:00097992040.037
nephron tubule morphogenesisGO:007207810.037
cellular response to external stimulusGO:007149620.037
regulation of jak stat cascadeGO:004642530.037
female gonad developmentGO:000858540.037
negative regulation of gene expressionGO:0010629650.037
somitogenesisGO:0001756870.037
regulation of signal transductionGO:00099662250.037
stem cell proliferationGO:007208940.037
regulation of cellular biosynthetic processGO:00313262450.036
apoptotic process involved in developmentGO:190274220.036
muscle cell developmentGO:00550011150.036
morphogenesis of an epitheliumGO:00020093330.035
cell motilityGO:00488702440.035
mesenchyme developmentGO:00604851270.035
apoptotic processGO:00069151160.035
embryonic skeletal system morphogenesisGO:0048704930.035
positive regulation of signalingGO:0023056560.035
striated muscle cell developmentGO:00550021080.035
cellular ketone metabolic processGO:0042180110.035
cell surface receptor signaling pathwayGO:00071663250.035
multi organism processGO:00517041340.035
gland developmentGO:00487321430.034
nephron morphogenesisGO:007202820.034
locomotionGO:00400113130.034
cellular component movementGO:00069283350.034
embryonic organ morphogenesisGO:00485622740.034
embryo development ending in birth or egg hatchingGO:00097922710.034
regulation of circadian rhythmGO:004275240.034
olfactory bulb developmentGO:002177240.033
heterocycle biosynthetic processGO:00181302150.033
inner ear developmentGO:00488391260.033
organic acid metabolic processGO:0006082310.033
protein localization to nucleusGO:003450430.033
chemotaxisGO:00069351040.032
localization of cellGO:00516742440.032
regulation of blood pressureGO:000821710.032
positive regulation of jak stat cascadeGO:004642720.032
regulation of signalingGO:00230512350.032
guanosine containing compound catabolic processGO:190106920.032
small molecule metabolic processGO:0044281770.032
regulation of stem cell proliferationGO:007209120.032
neuromuscular process controlling balanceGO:005088530.031
glial cell migrationGO:000834730.031
negative regulation of signalingGO:0023057960.031
cellular component morphogenesisGO:00329893360.031
embryonic organ developmentGO:00485683810.031
negative regulation of myeloid cell differentiationGO:004563810.031
regionalizationGO:00030022740.031
negative regulation of reproductive processGO:200024230.031
cellular biosynthetic processGO:00442492860.030
sensory organ morphogenesisGO:00905962000.030
regulation of cellular ketone metabolic processGO:001056570.030
anterior posterior pattern specificationGO:00099521520.029
phosphorus metabolic processGO:00067931090.029
lipid storageGO:001991510.029
embryonic cranial skeleton morphogenesisGO:0048701900.029
regulation of synapse assemblyGO:005196330.029
hepaticobiliary system developmentGO:0061008980.029
regulation of metal ion transportGO:001095940.029
regulation of multicellular organismal processGO:00512392770.029
epithelial cell differentiationGO:00308551160.029
cellular response to lipopolysaccharideGO:007122230.029
positive regulation of macromolecule metabolic processGO:0010604930.028
positive regulation of biological processGO:00485182530.028
positive regulation of gene expressionGO:0010628710.028
regulation of nucleic acid templated transcriptionGO:19035062130.028
system processGO:00030081850.028
positive regulation of nitrogen compound metabolic processGO:0051173690.028
heart morphogenesisGO:00030071560.028
cellular response to molecule of bacterial originGO:007121930.027
membrane repolarizationGO:008600920.027
positive regulation of transportGO:005105020.027
cell migrationGO:00164772370.027
erk1 and erk2 cascadeGO:007037140.027
dorsal ventral pattern formationGO:00099531250.027
regulation of cellular amino acid metabolic processGO:000652100.027
nucleocytoplasmic transportGO:000691340.027
negative regulation of response to stimulusGO:00485851040.027
establishment of localizationGO:00512342440.027
gtp metabolic processGO:004603940.027
specification of axis polarityGO:006500140.026
positive regulation of cell cycleGO:004578730.026
negative regulation of developmental processGO:0051093650.026
negative regulation of macromolecule metabolic processGO:0010605760.025
cell projection morphogenesisGO:00488582440.025
positive regulation of mesenchymal cell proliferationGO:000205310.025
taxisGO:00423301090.025
regulation of cell shapeGO:000836010.025
apoptotic process involved in morphogenesisGO:006056120.025
regulation of mesenchymal cell proliferationGO:001046410.025
cellular amine metabolic processGO:004410620.024
amine metabolic processGO:000930820.024
developmental programmed cell deathGO:001062340.024
antimicrobial humoral responseGO:001973020.024
positive regulation of cellular amino acid metabolic processGO:004576400.024
cellular response to chemical stimulusGO:00708871570.024
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.024
negative regulation of protein phosphorylationGO:000193340.024
negative regulation of biosynthetic processGO:0009890550.024
guanosine containing compound metabolic processGO:190106840.024
carboxylic acid metabolic processGO:0019752220.024
positive regulation of macromolecule biosynthetic processGO:0010557590.024
negative regulation of wnt signaling pathwayGO:0030178300.023
hematopoietic or lymphoid organ developmentGO:00485341910.023
neuronal stem cell maintenanceGO:009715020.023
cell fate commitmentGO:0045165990.023
brain developmentGO:00074202930.023
positive regulation of biosynthetic processGO:0009891680.023
hypothalamus cell differentiationGO:002197940.023
posterior lateral line neuromast primordium migrationGO:0048920120.023
multicellular organism growthGO:003526440.022
posterior lateral line neuromast developmentGO:0048919200.022
transcription from rna polymerase ii promoterGO:0006366800.022
tissue regenerationGO:0042246740.022
somatic stem cell maintenanceGO:003501910.022
single organism localizationGO:19025782250.022
cell deathGO:00082191210.022
gtp catabolic processGO:000618420.022
olfactory lobe developmentGO:002198840.022
regulation of organ growthGO:004662030.022
cell morphogenesisGO:00009022890.022
transportGO:00068102200.022
myeloid cell differentiationGO:0030099860.022
positive regulation of rna biosynthetic processGO:1902680570.021
eye developmentGO:00016542770.021
mesenchymal cell differentiationGO:0048762870.021
regulation of bindingGO:005109830.021
protein import into nucleusGO:000660630.021
neurotransmitter secretionGO:000726920.021
retina development in camera type eyeGO:00600411460.021
regulation of blood vessel sizeGO:005088020.021
regulation of rna biosynthetic processGO:20011412130.021
striated muscle cell differentiationGO:00511461290.021
heart loopingGO:0001947940.020
positive regulation of cellular amine metabolic processGO:003324000.020
epithelial tube morphogenesisGO:00605621480.020
negative regulation of cellular metabolic processGO:0031324770.020
regulation of peptidyl tyrosine phosphorylationGO:005073010.020
nerve developmentGO:0021675450.020
cell projection organizationGO:00300302840.020
positive regulation of nucleobase containing compound metabolic processGO:0045935690.020
deathGO:00162651210.020
regulation of retina development in camera type eyeGO:190286620.020
positive regulation of stem cell proliferationGO:200064810.020
mesenchymal cell developmentGO:0014031780.020
cellular response to biotic stimulusGO:007121630.020
regulation of intracellular protein transportGO:003315730.020
single organism nuclear importGO:190259330.020
oxoacid metabolic processGO:0043436310.020
regulation of protein transportGO:005122330.020
peripheral nervous system developmentGO:0007422550.020
regulation of synaptic growth at neuromuscular junctionGO:000858210.020
cognitionGO:005089010.019
odontogenesis of dentin containing toothGO:004247510.019
pharyngeal muscle developmentGO:004328240.019
cellular component assembly involved in morphogenesisGO:00109271070.019
female sex differentiationGO:004666040.019
somite developmentGO:0061053960.019
cell part morphogenesisGO:00329902460.019
negative regulation of stem cell differentiationGO:200073720.019
intracellular signal transductionGO:0035556850.019
proximal distal pattern formationGO:000995410.019
protein metabolic processGO:00195381830.019
specification of organ identityGO:001009220.019
regulation of ion transmembrane transporter activityGO:003241220.019
regulation of canonical wnt signaling pathwayGO:0060828340.018
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.018
wound healingGO:0042060900.018
neuron projection developmentGO:00311751800.018
positive regulation of rna metabolic processGO:0051254590.018
regulation of establishment of protein localizationGO:007020140.018
muscle cell differentiationGO:00426921390.018
protein targeting to nucleusGO:004474430.018
cell proliferationGO:0008283800.018
regulation of cell morphogenesisGO:0022604420.018
response to bacteriumGO:0009617580.018
neuron differentiationGO:00301823530.018
eye morphogenesisGO:00485921440.018
regulation of nucleoside metabolic processGO:000911820.018
cellular amide metabolic processGO:004360340.018
positive regulation of signal transductionGO:0009967560.018
regulation of anatomical structure morphogenesisGO:00226031300.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.018
diencephalon developmentGO:0021536580.018
maintenance of locationGO:005123540.018
regulation of molecular functionGO:0065009700.018
regulation of multicellular organism growthGO:004001440.018
regulation of extrinsic apoptotic signaling pathwayGO:200123630.018
positive regulation of transcription dna templatedGO:0045893570.017
positive regulation of striated muscle tissue developmentGO:004584410.017
negative regulation of nitrogen compound metabolic processGO:0051172590.017
protein importGO:001703830.017
regulation of locomotionGO:0040012550.017
epidermis developmentGO:0008544480.017
programmed cell deathGO:00125011190.017
positive regulation of cellular processGO:00485222010.017
homeostasis of number of cellsGO:0048872620.017
response to external biotic stimulusGO:0043207970.017
embryonic heart tube developmentGO:00350501330.017
sensory perception of painGO:001923310.017
lipid metabolic processGO:0006629520.017
macromolecule modificationGO:00434121110.017
blood vessel endothelial cell migrationGO:0043534180.017
ion transmembrane transportGO:0034220910.017
positive regulation of epithelial cell migrationGO:001063420.017
glial cell proliferationGO:001400940.017
negative regulation of signal transductionGO:0009968940.017
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.017
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.017
cellular response to extracellular stimulusGO:003166820.017
leukocyte proliferationGO:007066110.017
response to other organismGO:0051707970.017
neurological system processGO:0050877620.017
mesenchymal cell proliferationGO:001046310.016
fertilizationGO:000956630.016
cellular response to nutrient levelsGO:003166920.016
blood circulationGO:0008015870.016
camera type eye morphogenesisGO:00485931080.016
forebrain developmentGO:0030900960.016
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.016
regulation of membrane potentialGO:0042391230.016
morphogenesis of a branching structureGO:0001763210.016
ovulation cycle processGO:002260220.016
homeostatic processGO:00425921420.016
developmental growthGO:00485891660.016
determination of left right asymmetry in nervous systemGO:003554540.016
erythrocyte differentiationGO:0030218540.016
canonical wnt signaling pathwayGO:0060070480.016
negative regulation of cell differentiationGO:0045596460.016
cellular amino acid metabolic processGO:000652070.016
cellular protein modification processGO:00064641000.016
lymphocyte proliferationGO:004665110.016
cellular localizationGO:0051641970.016
compound eye developmentGO:004874920.016
regulation of heart growthGO:006042020.016
myeloid cell homeostasisGO:0002262560.016
muscle fiber developmentGO:0048747520.016
erythrocyte homeostasisGO:0034101550.016
regulation of transporter activityGO:003240920.016
regulation of protein bindingGO:004339330.016
otic vesicle morphogenesisGO:0071600340.016
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.016
cell morphogenesis involved in differentiationGO:00009041950.016
activation of mapk activityGO:000018730.016
regulation of tube sizeGO:003515020.016
hormone transportGO:000991420.016
regulation of purine nucleotide catabolic processGO:003312120.016
regulation of catenin import into nucleusGO:003541220.016
negative regulation of protein kinase activityGO:000646940.016
negative regulation of transcription dna templatedGO:0045892450.015
regulation of skeletal muscle tissue developmentGO:004864140.015
somatic muscle developmentGO:000752540.015
carbohydrate derivative metabolic processGO:1901135610.015
response to drugGO:004249330.015
axon developmentGO:00615641660.015
ear developmentGO:00435831270.015
zymogen activationGO:003163830.015
liver developmentGO:0001889960.015
post embryonic organ developmentGO:004856940.015
development of primary female sexual characteristicsGO:004654540.015
angiogenesisGO:00015251580.015
muscle organ developmentGO:00075171010.015
b cell differentiationGO:003018310.015
regulation of skeletal muscle fiber developmentGO:004874220.015
nuclear transportGO:005116940.015
muscle cell migrationGO:001481240.015
positive regulation of developmental processGO:0051094500.015
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.015
positive regulation of gliogenesisGO:001401520.015
positive regulation of cell communicationGO:0010647560.015
regulation of programmed cell deathGO:00430671010.015
organelle assemblyGO:00709251100.015
purine ribonucleoside monophosphate catabolic processGO:000916940.015
lymph vessel morphogenesisGO:0036303250.015
regulation of apoptotic processGO:0042981980.015
regulation of wnt signaling pathwayGO:0030111530.014
mitochondrion organizationGO:000700540.014
positive regulation of epithelial cell differentiationGO:003085820.014
stem cell divisionGO:001714510.014
establishment of protein localization to organelleGO:007259440.014
hormone secretionGO:004687920.014
negative regulation of catabolic processGO:000989530.014
peptidyl serine modificationGO:001820920.014
reflexGO:006000420.014
carbohydrate biosynthetic processGO:001605110.014
exocytosisGO:000688710.014
epidermal cell differentiationGO:0009913360.014
regulation of sodium ion transportGO:000202820.014
cardiac atrium developmentGO:000323040.014
determination of bilateral symmetryGO:00098552040.014
phosphate containing compound metabolic processGO:00067961080.014
positive regulation of cellular component biogenesisGO:004408930.014
inner ear receptor cell fate commitmentGO:006012040.014
action potentialGO:0001508190.014
regulation of response to cytokine stimulusGO:006075930.014
single organism transportGO:00447652060.014
syncytium formationGO:0006949120.014
regulation of sequestering of calcium ionGO:005128240.014
multi organism cellular processGO:004476420.014
dopaminergic neuron differentiationGO:0071542140.014
regulation of cytokine productionGO:000181730.014
mononuclear cell proliferationGO:003294310.014
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.014
regulation of localizationGO:00328791040.014
auditory receptor cell fate commitmentGO:000991240.014
embryonic limb morphogenesisGO:003032620.014
regulation of transcription from rna polymerase ii promoterGO:00063571140.014
developmental pigmentationGO:0048066480.014
regulation of neuron differentiationGO:0045664560.013
response to uvGO:000941130.013
actin filament based processGO:0030029640.013
regulation of cell activationGO:005086510.013
response to alkaloidGO:004327920.013
primitive hemopoiesisGO:0060215270.013
regulation of neuron migrationGO:200122220.013
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.013
innervationGO:006038430.013
protein dephosphorylationGO:000647030.013
determination of left right symmetryGO:00073681790.013
neuron projection extensionGO:1990138450.013
fin developmentGO:0033333770.013
positive regulation of muscle cell differentiationGO:005114910.013
tissue remodelingGO:004877140.013
smooth muscle contractionGO:000693920.013
glucose homeostasisGO:004259310.013
circulatory system processGO:0003013870.013
regulation of nucleotide catabolic processGO:003081120.013
ion transportGO:00068111140.013
positive regulation of cellular catabolic processGO:003133130.013
ovulation cycleGO:004269820.013
regulation of neurogenesisGO:0050767870.013
regulation of cell fate commitmentGO:0010453220.013
cellular carbohydrate metabolic processGO:004426240.013
negative regulation of leukocyte differentiationGO:190210610.013
positive regulation of erk1 and erk2 cascadeGO:007037420.013
cellular component biogenesisGO:00440851780.013
regulation of neurotransmitter transportGO:005158810.013
membrane hyperpolarizationGO:006008110.013
long chain fatty acid metabolic processGO:000167610.013
regulation of cellular amine metabolic processGO:003323800.013
b cell activationGO:004211320.013
pigment cell differentiationGO:0050931380.013
striated muscle tissue developmentGO:00147061100.013
positive regulation of cellular carbohydrate metabolic processGO:001067610.013
secondary metabolic processGO:001974830.013
atp catabolic processGO:000620040.013
positive regulation of cellular biosynthetic processGO:0031328680.013
digestive system developmentGO:00551232890.013
ribonucleoside monophosphate catabolic processGO:000915840.013
organelle organizationGO:00069962270.013
multicellular organismal response to stressGO:003355520.013
myeloid cell developmentGO:0061515320.013
positive regulation of muscle organ developmentGO:004863610.013
nuclear importGO:005117030.013
nuclear exportGO:005116810.013
stem cell differentiationGO:00488631170.013
neuron projection morphogenesisGO:00488121610.012
segmentationGO:0035282970.012
positive regulation of myeloid cell differentiationGO:004563920.012
positive regulation of secretionGO:005104710.012
adult behaviorGO:003053420.012
signal transduction in absence of ligandGO:003803410.012
skeletal muscle tissue developmentGO:0007519670.012
nucleoside monophosphate catabolic processGO:000912540.012
neuroblast proliferationGO:000740520.012
golgi vesicle transportGO:004819330.012
regulation of system processGO:0044057400.012
regulation of hormone secretionGO:004688320.012
positive regulation of striated muscle cell differentiationGO:005115510.012
hormone biosynthetic processGO:004244630.012
connective tissue developmentGO:0061448990.012
regulation of catalytic activityGO:0050790550.012
regulation of neurotransmitter secretionGO:004692810.012
regulation of protein metabolic processGO:0051246560.012
positive regulation of secretion by cellGO:190353210.012
germ line stem cell maintenanceGO:003071820.012
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.012
regulation of glial cell differentiationGO:004568540.012
inner ear morphogenesisGO:0042472630.012
multicellular organismal signalingGO:0035637220.012
gas transportGO:001566930.012
regulation of erythrocyte differentiationGO:004564620.012
positive regulation of carbohydrate metabolic processGO:004591310.012

dkk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.026
immune system diseaseDOID:291400.025
hematopoietic system diseaseDOID:7400.021
nervous system diseaseDOID:86300.020
disease of metabolismDOID:001466700.020
disease of cellular proliferationDOID:1456600.014
inherited metabolic disorderDOID:65500.013
organ system cancerDOID:005068600.012
cancerDOID:16200.012