Danio rerio

102 known processes

piwil2

piwi-like 2 (Drosophila)

(Aliases: zili,si:dkey-88f5.1)

piwil2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pole plasm assemblyGO:000731540.975
Fly
oocyte anterior posterior axis specificationGO:000731440.842
Fly
gamete generationGO:0007276330.772
regulation of primary metabolic processGO:00800903110.743
Mouse Fly
oocyte differentiationGO:0009994140.628
Fly
cellular aromatic compound metabolic processGO:00067252950.591
meiotic cell cycle processGO:190304630.589
Mouse
meiosis iiGO:000713510.579
oogenesisGO:0048477140.562
Mouse Fly
meiotic nuclear divisionGO:000712640.551
negative regulation of feeding behaviorGO:200025220.549
oocyte maturationGO:000155640.536
Fly
meiosis iGO:000712710.533
Mouse
regulation of multicellular organismal developmentGO:20000262230.525
Fly
multicellular organism reproductionGO:0032504350.506
transcription dna templatedGO:00063511810.492
Fly
organic cyclic compound metabolic processGO:19013603010.489
regulation of cellular metabolic processGO:00313233200.471
Mouse Fly
regulation of programmed cell deathGO:00430671010.467
meiotic chromosome segregationGO:004513230.462
oocyte developmentGO:0048599140.461
Fly
rna biosynthetic processGO:00327741810.434
Fly
cellular process involved in reproduction in multicellular organismGO:0022412280.411
Zebrafish Mouse Fly
rna metabolic processGO:00160702190.374
germ cell developmentGO:0007281220.374
Zebrafish Mouse Fly
chromosome organization involved in meiosisGO:007019210.372
regulation of biosynthetic processGO:00098892500.361
Mouse Fly
multi organism reproductive processGO:0044703360.339
regulation of cellular protein metabolic processGO:0032268520.334
Mouse
cellular macromolecule metabolic processGO:00442603910.334
cellular component movementGO:00069283350.322
aromatic compound biosynthetic processGO:00194382170.314
Fly
nucleobase containing compound metabolic processGO:00061392740.308
spermatid developmentGO:000728620.305
regulation of apoptotic processGO:0042981980.300
regulation of cell deathGO:00109411030.295
regulation of transcription dna templatedGO:00063552130.293
Fly
single organism reproductive processGO:0044702400.282
cellular biosynthetic processGO:00442492860.264
Mouse Fly
regulation of nucleic acid templated transcriptionGO:19035062130.258
Fly
regulation of signalingGO:00230512350.257
sexual reproductionGO:0019953360.246
macromolecule biosynthetic processGO:00090592270.245
Mouse Fly
dorsal ventral pattern formationGO:00099531250.242
regulation of rna biosynthetic processGO:20011412130.241
Fly
regulation of metabolic processGO:00192223590.236
multicellular organism growthGO:003526440.236
cellular nitrogen compound metabolic processGO:00346412900.226
programmed cell deathGO:00125011190.218
negative regulation of biological processGO:00485193040.208
chemical homeostasisGO:0048878490.191
cell surface receptor signaling pathwayGO:00071663250.190
anion transportGO:0006820380.188
deathGO:00162651210.184
regulation of biological qualityGO:00650082630.180
organic substance biosynthetic processGO:19015762890.176
Mouse Fly
regulation of gene expressionGO:00104682650.175
regionalizationGO:00030022740.174
Fly
organelle fissionGO:0048285230.173
growthGO:00400071740.172
multi organism processGO:00517041340.170
homeostatic processGO:00425921420.169
immune system processGO:00023762410.168
Fly
reproductive processGO:0022414400.166
neuron differentiationGO:00301823530.164
negative regulation of cellular processGO:00485232830.160
regulation of cellular biosynthetic processGO:00313262450.157
Mouse Fly
regulation of response to stimulusGO:00485832690.152
nucleic acid metabolic processGO:00903042440.151
ear developmentGO:00435831270.147
nitrogen compound metabolic processGO:00068073190.146
positive regulation of cellular processGO:00485222010.140
Mouse Fly
developmental maturationGO:0021700340.137
Fly
positive regulation of metabolic processGO:00098931080.134
female gamete generationGO:0007292140.132
Mouse Fly
central nervous system developmentGO:00074173870.130
cytoplasm organizationGO:000702840.127
Fly
male meiosisGO:000714020.125
response to abiotic stimulusGO:00096281220.123
oocyte axis specificationGO:000730950.122
Fly
immune system developmentGO:00025201910.117
single organism transportGO:00447652060.116
regulation of macromolecule metabolic processGO:00602553170.115
spermatogenesisGO:000728370.113
Mouse Fly
regulation of macromolecule biosynthetic processGO:00105562250.112
Mouse Fly
head developmentGO:00603223030.111
regulation of oocyte developmentGO:006028130.109
Fly
convergent extensionGO:00600261180.109
reproductionGO:0000003400.107
regulation of nitrogen compound metabolic processGO:00511712510.102
Fly
cellular response to organic substanceGO:00713101050.101
cellular nitrogen compound biosynthetic processGO:00442712180.101
Fly
endodermal cell fate determinationGO:000749320.101
negative regulation of apoptotic processGO:0043066550.099
negative regulation of cell deathGO:0060548600.099
regulation of embryonic developmentGO:0045995470.096
Fly
embryonic organ morphogenesisGO:00485622740.093
neuron projection developmentGO:00311751800.093
digestive tract developmentGO:00485652650.092
response to chemicalGO:00422213200.091
rna localizationGO:000640340.089
Fly
anterior posterior axis specificationGO:0009948200.088
Fly
digestive system developmentGO:00551232890.088
apoptotic processGO:00069151160.087
oocyte constructionGO:000730850.086
Fly
establishment of localizationGO:00512342440.086
negative regulation of programmed cell deathGO:0043069580.085
regulation of response to oxidative stressGO:190288220.085
chromosome organizationGO:0051276310.084
Fly
sensory organ developmentGO:00074233930.084
ameboidal type cell migrationGO:00016671430.084
spermatid differentiationGO:004851520.083
embryonic pattern specificationGO:0009880440.083
Fly
development of primary female sexual characteristicsGO:004654540.083
heterocycle metabolic processGO:00464832900.081
hematopoietic or lymphoid organ developmentGO:00485341910.080
negative regulation of cell cycleGO:0045786140.080
cellular component assemblyGO:00226071700.079
cell motilityGO:00488702440.078
cell cycleGO:0007049930.074
rhythmic processGO:0048511210.073
organic cyclic compound biosynthetic processGO:19013622230.071
Fly
regulation of reproductive processGO:200024140.070
Fly
spemann organizer formationGO:0060061100.069
mitotic cell cycleGO:0000278640.068
Fly
multicellular organismal reproductive processGO:0048609350.067
tissue remodelingGO:004877140.067
regulation of protein metabolic processGO:0051246560.066
Mouse
regulation of multicellular organismal processGO:00512392770.066
Fly
maternal determination of anterior posterior axis embryoGO:000835840.065
Fly
regulation of cell communicationGO:00106462320.065
nucleic acid templated transcriptionGO:00976591810.064
Fly
developmental growthGO:00485891660.064
regulation of response to extracellular stimulusGO:003210410.063
larval developmentGO:000216420.063
negative regulation of mesodermal cell fate specificationGO:004266230.063
cell projection organizationGO:00300302840.062
female sex differentiationGO:004666040.061
cellular macromolecule biosynthetic processGO:00346452240.061
Mouse Fly
cellular response to chemical stimulusGO:00708871570.059
developmental growth involved in morphogenesisGO:0060560860.057
cell growthGO:0016049570.057
cell maturationGO:0048469230.056
Fly
segmentationGO:0035282970.055
Fly
nucleobase containing compound biosynthetic processGO:00346542050.053
Fly
positive regulation of cellular biosynthetic processGO:0031328680.052
Mouse
response to stressGO:00069502630.049
Fly
inner ear developmentGO:00488391260.049
sister chromatid cohesionGO:000706220.048
response to endogenous stimulusGO:0009719830.048
cellular response to drugGO:003569010.047
regulation of chromosome segregationGO:005198310.046
single organism organelle organizationGO:19025891990.046
Mouse Fly
positive regulation of cell divisionGO:005178120.046
Mouse
nuclear divisionGO:0000280230.046
anterior posterior pattern specificationGO:00099521520.046
Fly
macromolecular complex subunit organizationGO:0043933740.046
cell type specific apoptotic processGO:0097285220.045
smad protein complex assemblyGO:000718310.045
response to organic substanceGO:00100331530.044
negative regulation of gene expressionGO:0010629650.044
Zebrafish Mouse Fly
transportGO:00068102200.043
generation of neuronsGO:00486993850.043
heterocycle biosynthetic processGO:00181302150.043
Fly
bmp signaling pathway involved in heart joggingGO:0003303140.043
regulation of cell maturationGO:190342910.043
Fly
negative regulation of signal transductionGO:0009968940.041
anterior posterior axis specification embryoGO:000859550.040
Fly
cell cycle processGO:0022402530.040
Mouse Fly
dna metabolic processGO:0006259270.040
Mouse Fly
response to nitrogen compoundGO:1901698190.040
regulation of dna replicationGO:000627530.039
posttranscriptional gene silencingGO:001644130.039
Fly
cell deathGO:00082191210.039
negative regulation of mesoderm developmentGO:200038150.039
female meiotic divisionGO:000714320.038
germ line stem cell divisionGO:004207810.038
Fly
convergent extension involved in gastrulationGO:0060027710.038
locomotionGO:00400113130.038
tube morphogenesisGO:00352393490.038
cell morphogenesis involved in differentiationGO:00009041950.037
single organism cellular localizationGO:1902580460.037
Fly
mitotic cell cycle processGO:1903047480.037
Fly
negative regulation of cellular metabolic processGO:0031324770.037
Fly
female gonad developmentGO:000858540.036
cellular response to hormone stimulusGO:0032870390.036
cellular response to hypoxiaGO:007145610.036
regulation of autophagyGO:001050630.035
cellular localizationGO:0051641970.035
Fly
intracellular mrna localizationGO:000829810.035
Fly
positive regulation of cell communicationGO:0010647560.034
regulation of cell differentiationGO:00455951420.034
regulation of cell growthGO:0001558290.034
negative regulation of protein complex assemblyGO:003133310.033
regulation of cellular macromolecule biosynthetic processGO:20001122220.033
Mouse Fly
regulation of anatomical structure sizeGO:0090066330.032
positive regulation of map kinase activityGO:004340630.031
response to drugGO:004249330.031
synaptic transmissionGO:0007268350.031
positive regulation of mrna metabolic processGO:190331320.030
Fly
enzyme linked receptor protein signaling pathwayGO:00071671060.030
embryonic cranial skeleton morphogenesisGO:0048701900.030
urogenital system developmentGO:0001655970.029
neuron remodelingGO:001632210.029
agingGO:000756820.029
regulation of bmp signaling pathway involved in heart joggingGO:2000223120.029
cell migrationGO:00164772370.028
regulation of transcription from rna polymerase ii promoterGO:00063571140.028
embryonic axis specificationGO:0000578120.027
Fly
cell cycle g1 s phase transitionGO:004484310.027
activation of mapk activityGO:000018730.027
maintenance of locationGO:005123540.027
negative regulation of reproductive processGO:200024230.026
regulation of neuron differentiationGO:0045664560.026
axon extensionGO:0048675450.026
ion homeostasisGO:0050801410.026
regulation of membrane potentialGO:0042391230.026
neuron developmentGO:00486662620.025
organelle organizationGO:00069962270.025
negative regulation of metabolic processGO:0009892860.025
Zebrafish Mouse Fly
otic placode formationGO:0043049230.025
response to organic cyclic compoundGO:0014070510.025
regulation of developmental processGO:00507932470.025
gastrulationGO:00073692080.025
response to hormoneGO:0009725480.025
determination of heart left right asymmetryGO:00613711170.025
positive regulation of cell cycleGO:004578730.024
Mouse
sensory organ morphogenesisGO:00905962000.024
regulation of multicellular organism growthGO:004001440.024
embryonic organ developmentGO:00485683810.024
camera type eye developmentGO:00430102220.024
posttranscriptional regulation of gene expressionGO:0010608140.024
Mouse Fly
axial mesoderm formationGO:004832040.023
cellular component biogenesisGO:00440851780.023
regulation of mesoderm developmentGO:2000380110.023
female meiosis chromosome segregationGO:001632110.023
regulation of rna metabolic processGO:00512522240.023
Fly
meiotic spindle organizationGO:000021210.023
cellular response to decreased oxygen levelsGO:003629410.023
angiogenesisGO:00015251580.023
positive regulation of cellular catabolic processGO:003133130.023
Fly
tripartite regional subdivisionGO:000735150.023
Fly
fin regenerationGO:0031101510.023
eye morphogenesisGO:00485921440.022
cell morphogenesisGO:00009022890.022
biosynthetic processGO:00090582940.022
Mouse Fly
positive regulation of catabolic processGO:000989640.022
Fly
connective tissue developmentGO:0061448990.022
bmp signaling pathway involved in heart developmentGO:0061312150.022
developmental process involved in reproductionGO:0003006270.021
Zebrafish Mouse Fly
retina homeostasisGO:0001895120.021
cell projection morphogenesisGO:00488582440.021
positive regulation of transportGO:005105020.021
bone remodelingGO:004684920.021
localization of cellGO:00516742440.021
oligodendrocyte differentiationGO:0048709230.020
dna templated transcription initiationGO:000635210.020
positive regulation of cellular protein metabolic processGO:0032270220.020
Mouse
convergent extension involved in organogenesisGO:0060029100.020
gliogenesisGO:0042063450.020
regulation of neuron deathGO:1901214180.020
synapsisGO:000712910.020
regulation of developmental growthGO:0048638380.020
mesenchyme developmentGO:00604851270.019
regulation of nodal signaling pathwayGO:190010740.019
specification of organ identityGO:001009220.019
regulation of mrna catabolic processGO:006101330.019
Fly
axon developmentGO:00615641660.019
negative regulation of nucleocytoplasmic transportGO:004682320.019
cellular component morphogenesisGO:00329893360.018
Fly
negative regulation of signalingGO:0023057960.018
ion transportGO:00068111140.018
morphogenesis of an epitheliumGO:00020093330.018
cell cell signalingGO:0007267520.018
developmental cell growthGO:0048588520.018
bmp signaling pathwayGO:0030509520.018
skeletal system developmentGO:00015011810.018
determination of bilateral symmetryGO:00098552040.018
protein complex subunit organizationGO:0071822460.018
positive regulation of nitrogen compound metabolic processGO:0051173690.018
Fly
regulation of developmental pigmentationGO:004807060.018
negative regulation of developmental processGO:0051093650.018
stem cell maintenanceGO:001982740.017
macromolecule modificationGO:00434121110.017
Mouse
mesoderm developmentGO:0007498880.017
regulation of cellular component organizationGO:0051128860.017
regulation of molecular functionGO:0065009700.017
protein complex assemblyGO:0006461300.017
determination of left right symmetryGO:00073681790.017
camera type eye morphogenesisGO:00485931080.017
cell proliferationGO:0008283800.017
pancreas developmentGO:0031016840.017
blastoderm segmentationGO:000735060.017
Fly
cellular protein modification processGO:00064641000.017
adult behaviorGO:003053420.017
heterocycle catabolic processGO:0046700150.017
Fly
regulation of tube sizeGO:003515020.017
organ growthGO:0035265120.017
response to temperature stimulusGO:0009266150.016
regulation of protein phosphorylationGO:0001932180.016
regulation of circadian rhythmGO:004275240.016
regulation of cell cycleGO:0051726520.016
Mouse
cellular response to stressGO:0033554620.016
regulation of meiotic cell cycleGO:005144510.016
Mouse
astrocyte differentiationGO:004870810.016
negative regulation of oocyte developmentGO:006028320.016
positive regulation of cell deathGO:0010942290.016
regulation of gene expression epigeneticGO:0040029110.015
Mouse Fly
g1 s transition of mitotic cell cycleGO:000008210.015
cell cycle phase transitionGO:004477090.015
neuron deathGO:0070997210.015
negative regulation of response to stimulusGO:00485851040.015
positive regulation of macromolecule metabolic processGO:0010604930.015
glucose homeostasisGO:004259310.014
catabolic processGO:0009056320.014
Fly
gene expressionGO:00104672520.014
organonitrogen compound metabolic processGO:1901564740.014
regulation of endodermal cell fate specificationGO:0042663150.014
brain developmentGO:00074202930.014
transcription from rna polymerase ii promoterGO:0006366800.014
negative regulation of cellular biosynthetic processGO:0031327550.014
Fly
positive regulation of rna metabolic processGO:0051254590.014
Fly
regulation of metal ion transportGO:001095940.014
regulation of signal transductionGO:00099662250.014
chordate embryonic developmentGO:00430092710.014
regulation of dna metabolic processGO:0051052110.014
Fly
negative regulation of cellular protein metabolic processGO:0032269160.014
regulation of mitotic cell cycleGO:0007346250.014
positive regulation of biosynthetic processGO:0009891680.014
Mouse
regulation of catalytic activityGO:0050790550.014
positive regulation of lipid metabolic processGO:004583410.014
positive regulation of biological processGO:00485182530.013
ion transmembrane transportGO:0034220910.013
cellular carbohydrate metabolic processGO:004426240.013
regulation of nucleobase containing compound metabolic processGO:00192192500.013
Fly
hemopoiesisGO:00300971830.013
single organism localizationGO:19025782250.013
Fly
regulation of microtubule based movementGO:006063230.013
reciprocal dna recombinationGO:003582510.013
regulation of protein complex assemblyGO:004325430.012
protein modification processGO:00362111000.012
neuron apoptotic processGO:0051402200.012
peptidyl lysine methylationGO:001802230.012
determination of left right asymmetry in diencephalonGO:003546240.012
transmembrane transportGO:00550851200.012
regulation of intracellular protein transportGO:003315730.012
epithelial cilium movement involved in determination of left right asymmetryGO:006028780.012
kupffer s vesicle developmentGO:0070121500.012
regulation of synapse organizationGO:005080730.012
response to hypoxiaGO:0001666250.012
cell migration involved in heart developmentGO:0060973220.012
positive regulation of protein kinase b signalingGO:005189710.011
cell part morphogenesisGO:00329902460.011
small molecule metabolic processGO:0044281770.011
ectodermal placode morphogenesisGO:0071697320.011
positive regulation of programmed cell deathGO:0043068290.011
specification of organ positionGO:001015930.011
organelle localizationGO:0051640490.011
g2 m transition of mitotic cell cycleGO:000008640.011
axis specificationGO:0009798430.011
Fly
negative regulation of macromolecule biosynthetic processGO:0010558480.011
Fly
regulation of anatomical structure morphogenesisGO:00226031300.011
inner ear morphogenesisGO:0042472630.011
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:1900094170.011
alternative mrna splicing via spliceosomeGO:000038010.011
cytokinesisGO:000091030.011
synaptic vesicle transportGO:004848910.011
cognitionGO:005089010.011
renal system developmentGO:0072001940.011
positive regulation of gene expressionGO:0010628710.011
regenerationGO:0031099910.010
digestive tract morphogenesisGO:00485462310.010
regulation of cellular component movementGO:0051270550.010
protein metabolic processGO:00195381830.010
Mouse
nucleoside monophosphate catabolic processGO:000912540.010
determination of left right asymmetry in nervous systemGO:003554540.010
determination of dorsal ventral asymmetryGO:0048262340.010
pronephros developmentGO:0048793690.010
negative regulation of nitrogen compound metabolic processGO:0051172590.010
Fly
organic cyclic compound catabolic processGO:1901361150.010
Fly
hard palate developmentGO:006002240.010
male gamete generationGO:004823270.010
Mouse Fly
glial cell differentiationGO:0010001420.010
specification of symmetryGO:00097992040.010

piwil2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.045
nervous system diseaseDOID:86300.027
disease of cellular proliferationDOID:1456600.022
osteochondrodysplasiaDOID:225600.015
bone development diseaseDOID:008000600.015
bone diseaseDOID:008000100.015
connective tissue diseaseDOID:6500.015
musculoskeletal system diseaseDOID:1700.015