Danio rerio

0 known processes

gpn3

GPN-loop GTPase 3

(Aliases: si:dkey-83d9.3,MGC14560,MGC101903,zgc:101903,MGC173756,atpbd1c)

gpn3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.084
agingGO:000756820.074
establishment of protein localization to organelleGO:007259440.046
nitrogen compound metabolic processGO:00068073190.043
cellular nitrogen compound metabolic processGO:00346412900.041
multicellular organism growthGO:003526440.039
cellular macromolecule metabolic processGO:00442603910.039
regulation of multicellular organism growthGO:004001440.039
cellular aromatic compound metabolic processGO:00067252950.038
positive regulation of transportGO:005105020.037
modification dependent protein catabolic processGO:001994130.036
nucleobase containing compound metabolic processGO:00061392740.036
autophagyGO:000691440.035
heterocycle biosynthetic processGO:00181302150.035
amine metabolic processGO:000930820.034
cellular nitrogen compound biosynthetic processGO:00442712180.034
protein import into nucleusGO:000660630.034
aromatic compound biosynthetic processGO:00194382170.034
cellular protein catabolic processGO:004425740.034
nucleobase containing compound biosynthetic processGO:00346542050.033
regulation of cellular amine metabolic processGO:003323800.033
ubiquitin dependent protein catabolic processGO:000651130.033
rna metabolic processGO:00160702190.033
organic cyclic compound biosynthetic processGO:19013622230.032
phagocytosisGO:000690930.032
biosynthetic processGO:00090582940.032
organic substance biosynthetic processGO:19015762890.032
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.032
organic cyclic compound metabolic processGO:19013603010.032
cellular amine metabolic processGO:004410620.032
nuclear transportGO:005116940.032
heterocycle metabolic processGO:00464832900.031
proteolysis involved in cellular protein catabolic processGO:005160330.031
regulation of protein transportGO:005122330.031
regulation of cellular amino acid metabolic processGO:000652100.031
negative regulation of protein phosphorylationGO:000193340.031
proteasomal protein catabolic processGO:001049820.030
single organism nuclear importGO:190259330.030
protein localization to nucleusGO:003450430.030
maintenance of locationGO:005123540.029
transcription dna templatedGO:00063511810.029
modification dependent macromolecule catabolic processGO:004363230.029
regulation of nitrogen compound metabolic processGO:00511712510.029
nucleocytoplasmic transportGO:000691340.028
protein importGO:001703830.028
stem cell maintenanceGO:001982740.028
cellular biosynthetic processGO:00442492860.028
nucleic acid metabolic processGO:00903042440.028
protein targeting to nucleusGO:004474430.027
positive regulation of cell cycleGO:004578730.027
rna localizationGO:000640340.027
regulation of metal ion transportGO:001095940.027
gene expressionGO:00104672520.027
single organism metabolic processGO:00447102170.027
protein acetylationGO:000647320.027
regulation of rna metabolic processGO:00512522240.026
regulation of metabolic processGO:00192223590.026
regulation of biosynthetic processGO:00098892500.026
regulation of gene expressionGO:00104682650.026
regulation of establishment of protein localizationGO:007020140.026
regulation of cytokine productionGO:000181730.026
mitochondrion organizationGO:000700540.026
nuclear importGO:005117030.026
negative regulation of biological processGO:00485193040.026
central nervous system developmentGO:00074173870.026
regulation of macromolecule biosynthetic processGO:00105562250.025
internal protein amino acid acetylationGO:000647520.025
meiotic nuclear divisionGO:000712640.025
nucleic acid templated transcriptionGO:00976591810.025
regulation of transcription dna templatedGO:00063552130.025
positive regulation of cellular component biogenesisGO:004408930.025
cognitionGO:005089010.025
signal transductionGO:00071654550.025
regulation of protein localization to nucleusGO:190018020.025
regulation of macromolecule metabolic processGO:00602553170.025
peptidyl lysine acetylationGO:001839420.024
cellular ketone metabolic processGO:0042180110.024
cellular macromolecule biosynthetic processGO:00346452240.024
organonitrogen compound metabolic processGO:1901564740.024
regulation of protein complex assemblyGO:004325430.024
regulation of intracellular protein transportGO:003315730.024
lipid storageGO:001991510.023
cellular response to external stimulusGO:007149620.023
regulation of autophagyGO:001050630.023
regulation of mrna splicing via spliceosomeGO:004802430.023
regulation of cellular ketone metabolic processGO:001056570.023
response to stressGO:00069502630.023
regulation of protein catabolic processGO:004217610.023
regulation of rna biosynthetic processGO:20011412130.023
internal peptidyl lysine acetylationGO:001839320.022
regulation of protein targetingGO:190353320.022
guanosine containing compound metabolic processGO:190106840.022
positive regulation of catabolic processGO:000989640.022
cellular response to nutrient levelsGO:003166920.022
macromolecule biosynthetic processGO:00090592270.022
cellular amino acid metabolic processGO:000652070.022
protein metabolic processGO:00195381830.022
regulation of nucleobase containing compound metabolic processGO:00192192500.022
organic acid metabolic processGO:0006082310.022
regulation of protein import into nucleusGO:004230620.022
negative regulation of protein kinase activityGO:000646940.022
endosomal transportGO:001619720.022
regulation of cellular metabolic processGO:00313233200.021
cellular response to extracellular stimulusGO:003166820.021
cellular component movementGO:00069283350.021
organelle fusionGO:004828430.021
regulation of cytoplasmic transportGO:190364940.021
regulation of developmental processGO:00507932470.021
regulation of neural precursor cell proliferationGO:200017730.021
rna biosynthetic processGO:00327741810.021
regulation of nucleic acid templated transcriptionGO:19035062130.021
regulation of cell activationGO:005086510.021
regulation of cellular biosynthetic processGO:00313262450.021
membrane fusionGO:006102520.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.021
regulation of nucleocytoplasmic transportGO:004682220.021
cell surface receptor signaling pathwayGO:00071663250.021
regulation of primary metabolic processGO:00800903110.021
regulation of meiotic cell cycleGO:005144510.021
ribonucleoside monophosphate catabolic processGO:000915840.020
positive regulation of cellular catabolic processGO:003133130.020
atp catabolic processGO:000620040.020
centrosome organizationGO:005129710.020
stem cell proliferationGO:007208940.020
leukocyte proliferationGO:007066110.020
cell cycle g1 s phase transitionGO:004484310.020
positive regulation of dna metabolic processGO:005105410.020
i kappab kinase nf kappab signalingGO:000724940.020
regulation of cellular macromolecule biosynthetic processGO:20001122220.020
negative regulation of kinase activityGO:003367340.019
guanosine containing compound catabolic processGO:190106920.019
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.019
negative regulation of cellular processGO:00485232830.019
gtp catabolic processGO:000618420.019
positive regulation of biological processGO:00485182530.019
response to chemicalGO:00422213200.019
meiotic cell cycle processGO:190304630.019
cytokinesisGO:000091030.019
gtp metabolic processGO:004603940.019
oxoacid metabolic processGO:0043436310.019
morphogenesis of an epitheliumGO:00020093330.019
regulation of reproductive processGO:200024140.019
positive regulation of cellular amine metabolic processGO:003324000.019
positive regulation of cytokine productionGO:000181920.018
cellular response to starvationGO:000926710.018
regulation of stem cell proliferationGO:007209120.018
negative regulation of protein transportGO:005122430.018
single organism membrane fusionGO:004480120.018
regulation of mrna processingGO:005068430.018
small molecule metabolic processGO:0044281770.018
regulation of synaptic plasticityGO:004816710.018
mononuclear cell proliferationGO:003294310.018
cell part morphogenesisGO:00329902460.018
microtubule organizing center organizationGO:003102310.018
nucleoside monophosphate catabolic processGO:000912540.017
cellular response to lipopolysaccharideGO:007122230.017
purine ribonucleoside monophosphate catabolic processGO:000916940.017
protein localization to plasma membraneGO:007265910.017
carboxylic acid metabolic processGO:0019752220.017
negative regulation of cytoplasmic transportGO:190365020.017
translational initiationGO:000641330.017
adherens junction organizationGO:003433240.017
secondary metabolic processGO:001974830.017
extrinsic apoptotic signaling pathwayGO:009719130.017
regulation of bindingGO:005109830.017
neurotransmitter transportGO:000683620.017
positive regulation of immune effector processGO:000269930.017
locomotionGO:00400113130.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
regulation of chromosome segregationGO:005198310.017
regulation of protein modification by small protein conjugation or removalGO:190332030.016
macroautophagyGO:001623610.016
response to uvGO:000941130.016
transportGO:00068102200.016
regulation of cell shapeGO:000836010.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
positive regulation of protein complex assemblyGO:003133420.016
cellular component biogenesisGO:00440851780.016
cellular protein metabolic processGO:00442671290.016
cellular response to biotic stimulusGO:007121630.016
positive regulation of secretionGO:005104710.016
cellular response to molecule of bacterial originGO:007121930.016
neuron differentiationGO:00301823530.016
cell substrate adhesionGO:003158940.016
positive regulation of chromosome organizationGO:200125210.016
neuron developmentGO:00486662620.016
b cell activationGO:004211320.016
purine nucleoside monophosphate catabolic processGO:000912840.016
positive regulation of lymphocyte mediated immunityGO:000270810.016
transcription from rna polymerase ii promoterGO:0006366800.016
g1 s transition of mitotic cell cycleGO:000008210.016
synaptic growth at neuromuscular junctionGO:005112420.016
regulation of purine nucleotide catabolic processGO:003312120.016
generation of neuronsGO:00486993850.016
protein acylationGO:004354330.016
cell morphogenesisGO:00009022890.016
cellular carbohydrate metabolic processGO:004426240.015
single organism transportGO:00447652060.015
cellular component disassemblyGO:002241110.015
compound eye developmentGO:004874920.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
nuclear exportGO:005116810.015
positive regulation of stress activated mapk cascadeGO:003287430.015
lymphocyte proliferationGO:004665110.015
tube morphogenesisGO:00352393490.015
production of molecular mediator of immune responseGO:000244020.015
negative regulation of nucleocytoplasmic transportGO:004682320.015
response to drugGO:004249330.015
blood vessel developmentGO:00015682460.015
vacuolar transportGO:000703420.015
sensory organ developmentGO:00074233930.015
double strand break repairGO:000630230.015
cell projection morphogenesisGO:00488582440.015
phagocytosis engulfmentGO:000691110.015
protein dephosphorylationGO:000647030.015
erk1 and erk2 cascadeGO:007037140.015
establishment of localizationGO:00512342440.015
activation of mapk activityGO:000018730.015
positive regulation of jnk cascadeGO:004633030.015
negative regulation of protein localization to nucleusGO:190018120.015
embryonic organ developmentGO:00485683810.015
symbiosis encompassing mutualism through parasitismGO:004440340.015
vasculature developmentGO:00019442780.015
negative regulation of catabolic processGO:000989530.015
peptide transportGO:001583310.015
positive regulation of i kappab kinase nf kappab signalingGO:004312330.015
embryo development ending in birth or egg hatchingGO:00097922710.015
regulation of synapse assemblyGO:005196330.015
positive regulation of cytoskeleton organizationGO:005149530.015
negative regulation of intracellular transportGO:003238730.015
chemosensory behaviorGO:000763510.015
digestive system developmentGO:00551232890.015
lateral inhibitionGO:004633110.015
cell migrationGO:00164772370.015
rna modificationGO:000945120.015
regulation of synapse organizationGO:005080730.015
locomotor rhythmGO:004547530.015
regionalizationGO:00030022740.015
synaptic vesicle transportGO:004848910.015
regulation of nucleoside metabolic processGO:000911820.015
regulation of nucleotide catabolic processGO:003081120.014
heart developmentGO:00075073130.014
cellular response to oxygen levelsGO:007145310.014
regulation of erk1 and erk2 cascadeGO:007037240.014
regulation of sodium ion transportGO:000202820.014
protein modification processGO:00362111000.014
regulation of cell communicationGO:00106462320.014
peptide metabolic processGO:000651810.014
regulation of signalingGO:00230512350.014
negative regulation of mapk cascadeGO:004340940.014
protein polyubiquitinationGO:000020940.014
regulation of response to stimulusGO:00485832690.014
organelle organizationGO:00069962270.014
regulation of cellular protein catabolic processGO:190336210.014
synaptic vesicle localizationGO:009747910.014
regulation of multicellular organismal processGO:00512392770.014
meiotic chromosome segregationGO:004513230.014
regulation of protein ubiquitinationGO:003139630.014
spermatid developmentGO:000728620.014
establishment of synaptic vesicle localizationGO:009748010.014
immune system processGO:00023762410.014
single organism organelle organizationGO:19025891990.014
positive regulation of chromatin modificationGO:190331010.014
response to external stimulusGO:00096052640.014
multi organism cellular processGO:004476420.014
regulation of alternative mrna splicing via spliceosomeGO:000038110.014
macromolecule modificationGO:00434121110.014
negative regulation of intracellular protein transportGO:009031730.014
protein secretionGO:000930610.014
germ line stem cell maintenanceGO:003071820.014
regulation of neurotransmitter transportGO:005158810.014
mitochondrial transportGO:000683920.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
cellular response to chemical stimulusGO:00708871570.013
peptidyl serine modificationGO:001820920.013
neurotransmitter secretionGO:000726920.013
cell substrate junction assemblyGO:000704420.013
blood vessel morphogenesisGO:00485142160.013
regulation of transporter activityGO:003240920.013
positive regulation of cell activationGO:005086710.013
interspecies interaction between organismsGO:004441940.013
cellular component morphogenesisGO:00329893360.013
exocytosisGO:000688710.013
positive regulation of secretion by cellGO:190353210.013
head developmentGO:00603223030.013
nucleic acid transportGO:005065720.013
brain developmentGO:00074202930.013
mitotic dna integrity checkpointGO:004477440.013
system processGO:00030081850.013
regulation of calcium ion transportGO:005192420.013
regulation of dendrite developmentGO:005077330.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
gastrulationGO:00073692080.013
regulation of response to biotic stimulusGO:000283120.013
lipid catabolic processGO:001604240.013
intracellular mrna localizationGO:000829810.013
neuroblast proliferationGO:000740520.013
regulation of gtpase activityGO:004308720.013
neuron projection developmentGO:00311751800.013
single fertilizationGO:000733830.013
localization of cellGO:00516742440.013
female sex differentiationGO:004666040.013
alternative mrna splicing via spliceosomeGO:000038010.013
chordate embryonic developmentGO:00430092710.013
cell motilityGO:00488702440.013
negative regulation of metabolic processGO:0009892860.013
mitotic dna damage checkpointGO:004477340.013
neuron neuron synaptic transmissionGO:000727010.013
small molecule catabolic processGO:004428230.013
cellular amide metabolic processGO:004360340.013
cell matrix adhesionGO:000716040.013
negative regulation of cytokine productionGO:000181810.013
macromolecular complex disassemblyGO:003298410.013
mitotic g2 m transition checkpointGO:004481830.013
growthGO:00400071740.013
regulation of dna replicationGO:000627530.012
viral processGO:001603210.012
immune system developmentGO:00025201910.012
negative regulation of protein import into nucleusGO:004230820.012
protein complex disassemblyGO:004324110.012
regulation of biological qualityGO:00650082630.012
negative regulation of cellular catabolic processGO:003133030.012
regulation of organ growthGO:004662030.012
response to carbohydrateGO:000974330.012
cellular component assemblyGO:00226071700.012
antimicrobial humoral responseGO:001973020.012
single organism localizationGO:19025782250.012
hemopoiesisGO:00300971830.012
regulation of circadian rhythmGO:004275240.012
regulation of gtp catabolic processGO:003312420.012
regulation of multicellular organismal developmentGO:20000262230.012
cellular response to decreased oxygen levelsGO:003629410.012
dorsal ventral pattern formationGO:00099531250.012
carbohydrate homeostasisGO:003350010.012
double strand break repair via homologous recombinationGO:000072410.012
peptidyl serine phosphorylationGO:001810510.012
spermatid differentiationGO:004851520.012
regulation of anatomical structure morphogenesisGO:00226031300.012
dna templated transcription elongationGO:000635430.012
tissue remodelingGO:004877140.012
phosphate containing compound metabolic processGO:00067961080.012
membrane invaginationGO:001032410.012
golgi vesicle transportGO:004819330.012
digestive tract developmentGO:00485652650.012
cytoskeleton dependent cytokinesisGO:006164030.012
positive regulation of nucleotide catabolic processGO:003081310.012
adult behaviorGO:003053420.012
rna transportGO:005065820.012
fertilizationGO:000956630.012
primary neural tube formationGO:001402010.012
regulation of production of molecular mediator of immune responseGO:000270010.012
female gonad developmentGO:000858540.012
cell cycle arrestGO:000705010.012
angiogenesisGO:00015251580.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
centrosome cycleGO:000709810.012
developmental growthGO:00485891660.012
deathGO:00162651210.012
positive regulation of cellular processGO:00485222010.012
negative regulation of map kinase activityGO:004340720.012
development of primary female sexual characteristicsGO:004654540.011
positive regulation of erk1 and erk2 cascadeGO:007037420.011
cellular protein modification processGO:00064641000.011
lipid homeostasisGO:005508830.011
regulation of ion transmembrane transporter activityGO:003241220.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
startle responseGO:000196440.011
carboxylic acid catabolic processGO:004639530.011
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.011
positive regulation of map kinase activityGO:004340630.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
negative regulation of nuclear divisionGO:005178430.011
neuromuscular synaptic transmissionGO:000727420.011
cell deathGO:00082191210.011
regulation of cell differentiationGO:00455951420.011
post embryonic organ developmentGO:004856940.011
tube closureGO:006060610.011
positive regulation of histone modificationGO:003105810.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
digestive tract morphogenesisGO:00485462310.011
positive regulation of translationGO:004572710.011
regulation of neurotransmitter secretionGO:004692810.011
cell projection organizationGO:00300302840.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
nucleobase containing compound transportGO:001593120.011
cell morphogenesis involved in differentiationGO:00009041950.011
regulation of organelle assemblyGO:190211540.011
rna 3 end processingGO:003112320.011
cellular response to hypoxiaGO:007145610.011
positive regulation of nucleoside metabolic processGO:004597910.011
positive regulation of leukocyte mediated immunityGO:000270510.011
somatic muscle developmentGO:000752540.011
toll like receptor signaling pathwayGO:000222440.011
meiosis iGO:000712710.011
sequestering of calcium ionGO:005120830.011
cellular response to stressGO:0033554620.011
negative regulation of epithelial cell proliferationGO:005068010.011
maternal determination of anterior posterior axis embryoGO:000835840.011
regulation of jak stat cascadeGO:004642530.011
response to monosaccharideGO:003428430.011
positive regulation of multi organism processGO:004390230.011
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.011
regulation of response to extracellular stimulusGO:003210410.011
regulation of epithelial cell proliferationGO:005067830.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
neuron projection morphogenesisGO:00488121610.010
positive regulation of apoptotic signaling pathwayGO:200123510.010
signal transduction in absence of ligandGO:003803410.010
establishment of rna localizationGO:005123630.010
regulation of signal transductionGO:00099662250.010
regulation of dna templated transcription elongationGO:003278430.010
rna export from nucleusGO:000640510.010
transcription elongation from rna polymerase ii promoterGO:000636830.010
glucose homeostasisGO:004259310.010
negative regulation of defense responseGO:003134820.010
response to nutrientGO:000758430.010
positive regulation of leukocyte differentiationGO:190210710.010
intracellular signal transductionGO:0035556850.010
calcium ion transport into cytosolGO:006040230.010
positive regulation of gtpase activityGO:004354710.010
recombinational repairGO:000072510.010

gpn3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.038
disease of metabolismDOID:001466700.022
nervous system diseaseDOID:86300.021
musculoskeletal system diseaseDOID:1700.018
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
inherited metabolic disorderDOID:65500.015
organ system cancerDOID:005068600.014
muscle tissue diseaseDOID:6600.013
muscular diseaseDOID:008000000.013
immune system diseaseDOID:291400.012
myopathyDOID:42300.010