Danio rerio

0 known processes

igfbp6b

insulin-like growth factor binding protein 6b

igfbp6b biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular extravasationGO:004512310.697
pericardium developmentGO:006003910.319
signal transductionGO:00071654550.233
sensory perception of chemical stimulusGO:000760630.232
cell surface receptor signaling pathwayGO:00071663250.220
pericardium morphogenesisGO:000334410.219
negative regulation of small gtpase mediated signal transductionGO:005105810.218
heart developmentGO:00075073130.192
tube morphogenesisGO:00352393490.179
multicellular organismal metabolic processGO:004423620.172
nitrogen compound metabolic processGO:00068073190.164
regulation of dna replicationGO:000627530.150
multicellular organism growthGO:003526440.142
g protein coupled receptor signaling pathwayGO:0007186740.132
positive regulation of camp biosynthetic processGO:003081920.132
larval developmentGO:000216420.130
sensory organ developmentGO:00074233930.130
agingGO:000756820.127
larval heart developmentGO:000750820.123
regulation of nucleobase containing compound metabolic processGO:00192192500.119
mitochondrion morphogenesisGO:007058420.118
cellular biosynthetic processGO:00442492860.118
regulation of establishment of protein localizationGO:007020140.116
regulation of signalingGO:00230512350.113
organic cyclic compound biosynthetic processGO:19013622230.113
cellular response to external stimulusGO:007149620.112
regulation of signal transductionGO:00099662250.112
cellular macromolecule metabolic processGO:00442603910.112
negative regulation of biological processGO:00485193040.110
response to bacteriumGO:0009617580.110
collagen metabolic processGO:003296320.108
establishment of protein localization to plasma membraneGO:009000210.107
central nervous system developmentGO:00074173870.106
vasculature developmentGO:00019442780.106
response to nutrientGO:000758430.104
negative regulation of ras protein signal transductionGO:004658010.103
organic cyclic compound metabolic processGO:19013603010.102
chordate embryonic developmentGO:00430092710.101
regulation of response to stimulusGO:00485832690.101
blood vessel morphogenesisGO:00485142160.098
germ line stem cell maintenanceGO:003071820.098
single organism localizationGO:19025782250.096
regulation of establishment of protein localization to plasma membraneGO:009000310.096
embryonic organ morphogenesisGO:00485622740.096
energy reserve metabolic processGO:000611220.096
regulation of multicellular organismal processGO:00512392770.092
negative regulation of response to stimulusGO:00485851040.089
cognitionGO:005089010.088
gastrulationGO:00073692080.085
sensory organ morphogenesisGO:00905962000.085
cellular nitrogen compound metabolic processGO:00346412900.085
angiogenesisGO:00015251580.083
regulation of biological qualityGO:00650082630.082
determination of bilateral symmetryGO:00098552040.082
regulation of cell communicationGO:00106462320.081
heterocycle metabolic processGO:00464832900.081
regulation of cellular metabolic processGO:00313233200.079
organic substance biosynthetic processGO:19015762890.079
response to vitaminGO:003327330.078
response to abiotic stimulusGO:00096281220.078
multicellular organismal macromolecule metabolic processGO:004425920.078
hindbrain developmentGO:0030902910.077
regulation of macromolecule metabolic processGO:00602553170.077
regulation of multicellular organismal metabolic processGO:004424620.077
cell cycle g1 s phase transitionGO:004484310.076
nucleobase containing compound biosynthetic processGO:00346542050.076
embryonic organ developmentGO:00485683810.075
regulation of metabolic processGO:00192223590.074
heterocycle biosynthetic processGO:00181302150.074
multi organism processGO:00517041340.072
regulation of cellular amino acid metabolic processGO:000652100.071
specification of symmetryGO:00097992040.071
cellular amine metabolic processGO:004410620.071
regulation of multicellular organism growthGO:004001440.071
digestive tract morphogenesisGO:00485462310.070
kupffer s vesicle developmentGO:0070121500.070
stem cell maintenanceGO:001982740.067
developmental growthGO:00485891660.065
g1 s transition of mitotic cell cycleGO:000008210.065
muscle structure developmentGO:00610611960.065
single organism biosynthetic processGO:0044711710.064
cellular response to extracellular stimulusGO:003166820.064
cellular nitrogen compound biosynthetic processGO:00442712180.064
cellular component movementGO:00069283350.063
regulation of nitrogen compound metabolic processGO:00511712510.063
response to other organismGO:0051707970.063
positive regulation of transportGO:005105020.062
response to ketoneGO:190165410.062
growthGO:00400071740.061
morphogenesis of an epithelial sheetGO:0002011490.061
positive regulation of biological processGO:00485182530.061
small molecule metabolic processGO:0044281770.060
locomotionGO:00400113130.060
negative regulation of cellular processGO:00485232830.060
regulation of collagen metabolic processGO:001071220.059
regulation of mitochondrion organizationGO:001082110.059
digestive system developmentGO:00551232890.059
positive regulation of secretion by cellGO:190353210.059
response to chemicalGO:00422213200.058
head developmentGO:00603223030.058
morphogenesis of an epitheliumGO:00020093330.057
digestive tract developmentGO:00485652650.057
energy homeostasisGO:009700930.057
dicarboxylic acid transportGO:000683510.057
cell matrix adhesionGO:000716040.056
ameboidal type cell migrationGO:00016671430.056
regulation of nucleic acid templated transcriptionGO:19035062130.055
skeletal system developmentGO:00015011810.054
muscle cell differentiationGO:00426921390.054
response to external stimulusGO:00096052640.053
transcription from rna polymerase ii promoterGO:0006366800.053
regulation of cellular amine metabolic processGO:003323800.053
response to stressGO:00069502630.053
cell substrate adhesionGO:003158940.052
single organism metabolic processGO:00447102170.051
regulation of bmp signaling pathwayGO:0030510390.051
brain developmentGO:00074202930.051
cardiac muscle tissue developmentGO:0048738480.050
regulation of developmental processGO:00507932470.049
regulation of biosynthetic processGO:00098892500.049
regulation of cellular biosynthetic processGO:00313262450.048
regulation of cellular macromolecule biosynthetic processGO:20001122220.048
muscle cell developmentGO:00550011150.048
mitochondrion organizationGO:000700540.047
rna biosynthetic processGO:00327741810.046
determination of left right symmetryGO:00073681790.046
aromatic compound biosynthetic processGO:00194382170.046
response to glucocorticoidGO:005138410.045
positive regulation of cellular amine metabolic processGO:003324000.045
regulation of protein complex assemblyGO:004325430.045
cell migration involved in gastrulationGO:0042074790.045
embryo development ending in birth or egg hatchingGO:00097922710.045
regulation of primary metabolic processGO:00800903110.045
single organism membrane fusionGO:004480120.043
cellular aromatic compound metabolic processGO:00067252950.043
alcohol biosynthetic processGO:004616520.043
single organism transportGO:00447652060.042
cellular ketone metabolic processGO:0042180110.042
regulation of cell shapeGO:000836010.042
localization of cellGO:00516742440.041
establishment of localizationGO:00512342440.041
cell proliferationGO:0008283800.041
cardiac muscle cell differentiationGO:0055007300.041
myofibril assemblyGO:0030239480.041
regulation of cellular extravasationGO:000269110.041
otic vesicle morphogenesisGO:0071600340.040
cell motilityGO:00488702440.040
ear developmentGO:00435831270.040
positive regulation of cell substrate adhesionGO:001081110.040
pyruvate metabolic processGO:000609010.040
nucleobase containing compound metabolic processGO:00061392740.039
biosynthetic processGO:00090582940.039
carboxylic acid metabolic processGO:0019752220.039
neuron developmentGO:00486662620.038
neuron differentiationGO:00301823530.038
eye developmentGO:00016542770.038
negative regulation of feeding behaviorGO:200025220.037
immune system processGO:00023762410.037
regulation of transcription dna templatedGO:00063552130.037
insulin like growth factor receptor signaling pathwayGO:004800940.037
negative regulation of signal transductionGO:0009968940.036
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.036
cellular macromolecule biosynthetic processGO:00346452240.036
cellular response to nutrient levelsGO:003166920.036
membrane fusionGO:006102520.036
camp biosynthetic processGO:0006171110.036
cellular aldehyde metabolic processGO:000608140.036
organelle assemblyGO:00709251100.036
positive regulation of cytokine productionGO:000181920.036
nucleic acid templated transcriptionGO:00976591810.035
response to decreased oxygen levelsGO:0036293250.035
adult behaviorGO:003053420.035
gtp catabolic processGO:000618420.035
cell migrationGO:00164772370.035
transportGO:00068102200.035
response to biotic stimulusGO:0009607970.034
androgen metabolic processGO:000820920.034
regulation of gene expressionGO:00104682650.034
response to organic substanceGO:00100331530.034
protein secretionGO:000930610.034
rna metabolic processGO:00160702190.034
amine metabolic processGO:000930820.033
positive regulation of cellular processGO:00485222010.033
negative regulation of rho protein signal transductionGO:003502410.033
homeostatic processGO:00425921420.032
blood vessel developmentGO:00015682460.032
skeletal muscle organ developmentGO:0060538780.032
transcription dna templatedGO:00063511810.032
negative regulation of multicellular organismal processGO:0051241690.032
regulation of rho protein signal transductionGO:003502320.032
cellular component biogenesisGO:00440851780.032
developmental growth involved in morphogenesisGO:0060560860.032
regulation of protein transportGO:005122330.031
regulation of cellular ketone metabolic processGO:001056570.031
programmed cell deathGO:00125011190.031
positive regulation of cell adhesionGO:004578510.031
post embryonic organ developmentGO:004856940.031
response to drugGO:004249330.031
sprouting angiogenesisGO:0002040530.031
positive regulation of nitrogen compound metabolic processGO:0051173690.031
regulation of camp biosynthetic processGO:003081790.031
striated muscle tissue developmentGO:00147061100.030
cellular response to chemical stimulusGO:00708871570.030
stem cell differentiationGO:00488631170.030
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.030
negative regulation of kinase activityGO:003367340.029
negative regulation of dna metabolic processGO:005105340.029
organic acid metabolic processGO:0006082310.029
actomyosin structure organizationGO:0031032530.029
striated muscle cell differentiationGO:00511461290.029
neuron projection extensionGO:1990138450.029
fat soluble vitamin metabolic processGO:000677540.029
oxoacid metabolic processGO:0043436310.029
axon developmentGO:00615641660.029
negative regulation of programmed cell deathGO:0043069580.029
cellular amino acid metabolic processGO:000652070.028
neurological system processGO:0050877620.028
striated muscle cell developmentGO:00550021080.028
negative regulation of protein phosphorylationGO:000193340.028
response to lipidGO:0033993600.028
gtp metabolic processGO:004603940.028
cellular component assembly involved in morphogenesisGO:00109271070.028
organic substance transportGO:0071702580.027
regulation of synaptic plasticityGO:004816710.027
cellular response to organic substanceGO:00713101050.027
negative regulation of developmental processGO:0051093650.027
response to hormoneGO:0009725480.027
cellular response to lipidGO:0071396390.027
neuron projection developmentGO:00311751800.026
cellular component morphogenesisGO:00329893360.026
organelle fusionGO:004828430.026
actin cytoskeleton organizationGO:0030036630.026
fin developmentGO:0033333770.026
organelle organizationGO:00069962270.026
negative regulation of bmp signaling pathwayGO:0030514130.026
regulation of systemic arterial blood pressureGO:000307310.026
negative regulation of cell communicationGO:0010648960.025
cell part morphogenesisGO:00329902460.025
germ cell migrationGO:000835480.025
protein localization to plasma membraneGO:007265910.025
regulation of blood pressureGO:000821710.025
stem cell proliferationGO:007208940.025
regulation of protein localization to plasma membraneGO:190307610.025
endocrine processGO:005088620.025
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.025
cell morphogenesisGO:00009022890.025
regulation of neuron differentiationGO:0045664560.025
endothelial cell migrationGO:0043542190.025
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.024
axonogenesisGO:00074091520.024
regulation of phGO:000688530.024
epithelial cell differentiationGO:00308551160.024
inner ear developmentGO:00488391260.024
single organism organelle organizationGO:19025891990.024
response to oxygen containing compoundGO:1901700550.024
positive regulation of cellular amino acid metabolic processGO:004576400.024
cardiocyte differentiationGO:0035051440.023
regulation of bindingGO:005109830.023
otic vesicle developmentGO:0071599420.023
cell deathGO:00082191210.023
organonitrogen compound metabolic processGO:1901564740.023
guanosine containing compound catabolic processGO:190106920.023
macromolecule biosynthetic processGO:00090592270.023
stem cell divisionGO:001714510.023
ubiquitin dependent protein catabolic processGO:000651130.023
regulation of intracellular signal transductionGO:1902531570.023
epithelial tube morphogenesisGO:00605621480.023
positive regulation of purine nucleotide biosynthetic processGO:190037380.023
negative regulation of secretion by cellGO:190353120.023
gene expressionGO:00104672520.023
maintenance of locationGO:005123540.023
ras protein signal transductionGO:000726570.022
regulation of cell substrate adhesionGO:001081010.022
system processGO:00030081850.022
circadian sleep wake cycleGO:004274520.022
stem cell developmentGO:0048864820.022
regulation of protein modification by small protein conjugation or removalGO:190332030.022
ion homeostasisGO:0050801410.022
regulation of cytokine productionGO:000181730.022
appendage developmentGO:0048736800.022
protein metabolic processGO:00195381830.022
generation of neuronsGO:00486993850.022
tissue migrationGO:0090130370.022
negative regulation of protein complex assemblyGO:003133310.022
organophosphate biosynthetic processGO:0090407230.021
cell growthGO:0016049570.021
positive regulation of apoptotic signaling pathwayGO:200123510.021
cellular component assemblyGO:00226071700.021
actin filament based processGO:0030029640.021
enzyme linked receptor protein signaling pathwayGO:00071671060.021
cell projection morphogenesisGO:00488582440.021
regulation of apoptotic processGO:0042981980.020
cell fate commitmentGO:0045165990.020
i kappab kinase nf kappab signalingGO:000724940.020
positive regulation of cell cycleGO:004578730.020
regulation of cell deathGO:00109411030.020
heart loopingGO:0001947940.020
negative regulation of signalingGO:0023057960.020
carbohydrate derivative biosynthetic processGO:1901137430.020
regulation of rna biosynthetic processGO:20011412130.020
cell adhesion mediated by integrinGO:003362710.020
negative regulation of macromolecule metabolic processGO:0010605760.020
oxidation reduction processGO:0055114410.019
regulation of transcription from rna polymerase ii promoterGO:00063571140.019
response to corticosteroidGO:003196010.019
bmp signaling pathwayGO:0030509520.019
gland developmentGO:00487321430.019
regulation of macromolecule biosynthetic processGO:00105562250.019
positive regulation of macromolecule metabolic processGO:0010604930.019
regulation of tube sizeGO:003515020.019
response to hypoxiaGO:0001666250.019
negative regulation of secretionGO:005104820.019
positive regulation of inflammatory responseGO:005072910.019
lipid storageGO:001991510.019
nucleocytoplasmic transportGO:000691340.019
regulation of developmental growthGO:0048638380.019
positive regulation of secretionGO:005104710.019
retina development in camera type eyeGO:00600411460.019
regulation of rna metabolic processGO:00512522240.019
camera type eye developmentGO:00430102220.019
inner ear morphogenesisGO:0042472630.018
lipid catabolic processGO:001604240.018
pharyngeal system developmentGO:0060037180.018
response to endogenous stimulusGO:0009719830.018
protein targeting to nucleusGO:004474430.018
symbiosis encompassing mutualism through parasitismGO:004440340.018
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.018
response to external biotic stimulusGO:0043207970.018
chemical homeostasisGO:0048878490.018
striated muscle contractionGO:0006941120.018
muscle organ developmentGO:00075171010.018
deathGO:00162651210.018
negative regulation of nitrogen compound metabolic processGO:0051172590.018
regulation of protein ubiquitinationGO:003139630.018
cyclic purine nucleotide metabolic processGO:0052652180.018
regulation of insulin like growth factor receptor signaling pathwayGO:004356710.018
mesoderm developmentGO:0007498880.018
positive regulation of programmed cell deathGO:0043068290.018
regulation of phosphorus metabolic processGO:0051174430.018
macromolecule modificationGO:00434121110.018
guanosine containing compound metabolic processGO:190106840.018
carbohydrate derivative metabolic processGO:1901135610.018
cell migration involved in sprouting angiogenesisGO:000204280.018
positive regulation of camp metabolic processGO:003081620.018
regulation of localizationGO:00328791040.017
cellular localizationGO:0051641970.017
cellular response to starvationGO:000926710.017
cellular amide metabolic processGO:004360340.017
cellular response to molecule of bacterial originGO:007121930.017
sensory perception of smellGO:000760820.017
epithelium migrationGO:0090132250.017
response to molecule of bacterial originGO:0002237140.017
long chain fatty acid metabolic processGO:000167610.017
regulation of locomotionGO:0040012550.017
protein localizationGO:0008104400.017
negative regulation of cytokine productionGO:000181810.017
chloride transmembrane transportGO:190247640.017
positive regulation of cell activationGO:005086710.017
nitric oxide biosynthetic processGO:000680920.017
regulation of organ growthGO:004662030.017
regulation of inflammatory responseGO:005072720.017
developmental cell growthGO:0048588520.017
phosphorus metabolic processGO:00067931090.017
single organism membrane organizationGO:0044802200.017
rho protein signal transductionGO:000726650.017
cellular protein modification processGO:00064641000.017
positive regulation of apoptotic processGO:0043065290.016
purine nucleotide biosynthetic processGO:0006164200.016
chemotaxisGO:00069351040.016
epithelial cell migrationGO:0010631250.016
small gtpase mediated signal transductionGO:000726480.016
axon extensionGO:0048675450.016
negative regulation of cellular biosynthetic processGO:0031327550.016
multicellular organismal response to stressGO:003355520.016
cell morphogenesis involved in differentiationGO:00009041950.016
response to carbohydrateGO:000974330.016
response to monosaccharideGO:003428430.016
positive regulation of protein polymerizationGO:003227320.016
membrane organizationGO:0061024210.016
nuclear transportGO:005116940.016
otic vesicle formationGO:0030916270.016
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:000718850.016
apoptotic processGO:00069151160.016
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:000718750.016
negative regulation of cell motilityGO:2000146170.016
regulation of intracellular protein transportGO:003315730.016
blood circulationGO:0008015870.016
negative regulation of nucleobase containing compound metabolic processGO:0045934590.016
heart morphogenesisGO:00030071560.016
blood vessel endothelial cell migrationGO:0043534180.015
toll like receptor signaling pathwayGO:000222440.015
tyrosine phosphorylation of stat proteinGO:000726010.015
exocrine system developmentGO:0035272280.015
protein modification processGO:00362111000.015
cellular carbohydrate metabolic processGO:004426240.015
regulation of cellular component movementGO:0051270550.015
behaviorGO:0007610740.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.015
muscle attachmentGO:001620390.015
sleepGO:003043110.015
regulation of cytoplasmic transportGO:190364940.015
macromolecular complex subunit organizationGO:0043933740.015
regulation of cellular component organizationGO:0051128860.015
neuron neuron synaptic transmissionGO:000727010.015
positive regulation of cell divisionGO:005178120.015
female sex differentiationGO:004666040.015
regulation of synapse assemblyGO:005196330.015
regulation of protein import into nucleusGO:004230620.015
regulation of dendrite developmentGO:005077330.015
multicellular organismal homeostasisGO:0048871290.015
camp metabolic processGO:0046058110.014
negative regulation of biosynthetic processGO:0009890550.014
regulation of programmed cell deathGO:00430671010.014
hormone secretionGO:004687920.014
multicellular organism reproductionGO:0032504350.014
positive regulation of cellular catabolic processGO:003133130.014
establishment of protein localization to organelleGO:007259440.014
hormone biosynthetic processGO:004244630.014
establishment of endothelial barrierGO:006102830.014
response to vitamin b3GO:003355220.014
phosphate containing compound metabolic processGO:00067961080.014
negative regulation of cell migrationGO:0030336170.014
regionalizationGO:00030022740.014
intracellular signal transductionGO:0035556850.014
positive regulation of catabolic processGO:000989640.014
phagocytosisGO:000690930.014
cell migration in hindbrainGO:002153570.014
purine containing compound biosynthetic processGO:0072522200.014
cell projection organizationGO:00300302840.014
embryonic heart tube morphogenesisGO:00031431080.014
positive regulation of cell killingGO:003134320.014
defense responseGO:0006952470.014
female gonad developmentGO:000858540.014
organonitrogen compound biosynthetic processGO:1901566470.014
positive regulation of response to stimulusGO:0048584800.014
negative regulation of intracellular transportGO:003238730.014
negative regulation of defense responseGO:003134820.014
regulation of heart growthGO:006042020.014
regulation of metal ion transportGO:001095940.014
regulation of cell motilityGO:2000145460.014
regulation of response to nutrient levelsGO:003210710.014
cyclic nucleotide metabolic processGO:0009187180.014
organism emergence from protective structureGO:007168440.013
cell morphogenesis involved in neuron differentiationGO:00486671630.013
negative regulation of cell deathGO:0060548600.013
regulation of protein catabolic processGO:004217610.013
actin filament bundle assemblyGO:005101760.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
golgi vesicle transportGO:004819330.013
meiotic cell cycle processGO:190304630.013
response to superoxideGO:000030320.013
cellular response to fatty acidGO:007139830.013
regulation of multicellular organismal developmentGO:20000262230.013
negative regulation of cell differentiationGO:0045596460.013
mesodermal cell differentiationGO:0048333210.013
peptide transportGO:001583310.013
positive regulation of cell deathGO:0010942290.013
positive regulation of endothelial cell proliferationGO:000193810.013
regulation of gtpase activityGO:004308720.013
circadian sleep wake cycle sleepGO:005080210.013
protein importGO:001703830.013
neurotransmitter secretionGO:000726920.013
protein stabilizationGO:005082120.013
muscle tissue developmentGO:00605371100.013
regulation of cell proliferationGO:0042127370.013
regulation of response to cytokine stimulusGO:006075930.013
primary neural tube formationGO:001402010.013
regulation of cell migrationGO:0030334400.013
determination of heart left right asymmetryGO:00613711170.013
glucocorticoid metabolic processGO:000821120.013
macromolecule localizationGO:0033036540.013
regulation of protein bindingGO:004339330.013
cellular hormone metabolic processGO:0034754190.013
regulation of purine nucleotide catabolic processGO:003312120.013
regulation of neurogenesisGO:0050767870.013
cell fate specificationGO:0001708680.013
regulation of phospholipase activityGO:001051720.013
regulation of carbohydrate metabolic processGO:000610940.013
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.012
cytoskeleton organizationGO:0007010960.012
negative regulation of catabolic processGO:000989530.012
dicarboxylic acid metabolic processGO:004364810.012
negative regulation of dna replicationGO:000815620.012
positive regulation of neuron deathGO:190121610.012
response to lipopolysaccharideGO:0032496130.012
carbohydrate homeostasisGO:003350010.012
nuclear importGO:005117030.012
synaptic vesicle localizationGO:009747910.012
intracellular receptor signaling pathwayGO:0030522300.012
negative regulation of metabolic processGO:0009892860.012
epibolyGO:0090504410.012
protein homooligomerizationGO:005126030.012

igfbp6b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.054
disease of metabolismDOID:001466700.018
musculoskeletal system diseaseDOID:1700.018
inherited metabolic disorderDOID:65500.016