Danio rerio

31 known processes

il4

interleukin 4

(Aliases: il-4,il4/13b)

il4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.079
signal transductionGO:00071654550.046
regulation of multicellular organism growthGO:004001440.041
agingGO:000756820.039
positive regulation of cell cycleGO:004578730.036
response to external stimulusGO:00096052640.035
cellular amine metabolic processGO:004410620.034
cellular ketone metabolic processGO:0042180110.033
regulation of cellular amine metabolic processGO:003323800.033
positive regulation of transportGO:005105020.033
cell surface receptor signaling pathwayGO:00071663250.032
regulation of cytokine productionGO:000181730.032
amine metabolic processGO:000930820.032
multicellular organism growthGO:003526440.031
positive regulation of stress activated mapk cascadeGO:003287430.031
maintenance of locationGO:005123540.031
regulation of cellular amino acid metabolic processGO:000652100.031
stem cell proliferationGO:007208940.030
biosynthetic processGO:00090582940.029
response to chemicalGO:00422213200.029
synaptic growth at neuromuscular junctionGO:005112420.028
positive regulation of cellular component biogenesisGO:004408930.028
cognitionGO:005089010.028
regulation of peptidyl tyrosine phosphorylationGO:005073010.027
regulation of synaptic plasticityGO:004816710.026
phagocytosisGO:000690930.026
regulation of cellular ketone metabolic processGO:001056570.026
generation of neuronsGO:00486993850.026
exocytosisGO:000688710.025
stem cell maintenanceGO:001982740.025
positive regulation of catabolic processGO:000989640.025
leukocyte proliferationGO:007066110.025
lipid storageGO:001991510.024
gtp catabolic processGO:000618420.024
small molecule metabolic processGO:0044281770.024
cellular response to external stimulusGO:007149620.024
regulation of synapse organizationGO:005080730.024
regulation of protein complex assemblyGO:004325430.024
guanosine containing compound catabolic processGO:190106920.024
guanosine containing compound metabolic processGO:190106840.023
regulation of cell communicationGO:00106462320.023
organic acid metabolic processGO:0006082310.023
organic substance biosynthetic processGO:19015762890.023
establishment of protein localization to organelleGO:007259440.023
negative regulation of protein phosphorylationGO:000193340.023
cellular response to starvationGO:000926710.023
regulation of metabolic processGO:00192223590.023
regulation of bindingGO:005109830.023
cellular nitrogen compound metabolic processGO:00346412900.023
single fertilizationGO:000733830.022
autophagyGO:000691440.022
nitrogen compound metabolic processGO:00068073190.022
positive regulation of cellular amine metabolic processGO:003324000.022
cytokinesisGO:000091030.022
regulation of autophagyGO:001050630.022
organonitrogen compound metabolic processGO:1901564740.022
positive regulation of cellular catabolic processGO:003133130.022
carboxylic acid metabolic processGO:0019752220.022
response to drugGO:004249330.022
cellular component disassemblyGO:002241110.021
negative regulation of protein kinase activityGO:000646940.021
cellular macromolecule metabolic processGO:00442603910.021
protein importGO:001703830.021
regulation of reproductive processGO:200024140.021
synaptic vesicle transportGO:004848910.021
heterocycle metabolic processGO:00464832900.021
cellular component morphogenesisGO:00329893360.021
neuron differentiationGO:00301823530.021
regulation of muscle contractionGO:000693730.021
adult behaviorGO:003053420.021
morphogenesis of an epitheliumGO:00020093330.021
positive regulation of cellular amino acid metabolic processGO:004576400.020
regulation of cellular metabolic processGO:00313233200.020
tissue remodelingGO:004877140.020
response to stressGO:00069502630.020
regulation of signal transductionGO:00099662250.020
oxoacid metabolic processGO:0043436310.020
protein localization to nucleusGO:003450430.020
cellular response to extracellular stimulusGO:003166820.020
membrane fusionGO:006102520.020
protein import into nucleusGO:000660630.020
regulation of protein transportGO:005122330.020
positive regulation of protein complex assemblyGO:003133420.020
cellular biosynthetic processGO:00442492860.020
cell projection organizationGO:00300302840.020
organic cyclic compound metabolic processGO:19013603010.020
modification dependent protein catabolic processGO:001994130.020
cellular response to nutrient levelsGO:003166920.020
cortical cytoskeleton organizationGO:003086510.020
cortical actin cytoskeleton organizationGO:003086610.020
regulation of multicellular organismal developmentGO:20000262230.019
nucleobase containing compound metabolic processGO:00061392740.019
carbohydrate biosynthetic processGO:001605110.019
i kappab kinase nf kappab signalingGO:000724940.019
cytoskeleton dependent cytokinesisGO:006164030.019
ubiquitin dependent protein catabolic processGO:000651130.019
immune system processGO:00023762410.019
regulation of macromolecule metabolic processGO:00602553170.019
protein targeting to nucleusGO:004474430.019
regulation of establishment of protein localizationGO:007020140.019
regionalizationGO:00030022740.019
regulation of gene expressionGO:00104682650.019
regulation of response to stimulusGO:00485832690.019
single organism membrane fusionGO:004480120.019
gtp metabolic processGO:004603940.019
macromolecular complex disassemblyGO:003298410.018
positive regulation of biological processGO:00485182530.018
gene expressionGO:00104672520.018
organelle fusionGO:004828430.018
regulation of nucleoside metabolic processGO:000911820.018
response to carbohydrateGO:000974330.018
cellular component movementGO:00069283350.018
regulation of synapse assemblyGO:005196330.018
regulation of biological qualityGO:00650082630.018
regulation of stem cell differentiationGO:200073640.018
nuclear transportGO:005116940.018
cellular carbohydrate metabolic processGO:004426240.018
regulation of purine nucleotide catabolic processGO:003312120.018
negative regulation of cytokine productionGO:000181810.018
cell part morphogenesisGO:00329902460.018
nucleocytoplasmic transportGO:000691340.018
somatic muscle developmentGO:000752540.017
establishment of synaptic vesicle localizationGO:009748010.017
single organism nuclear importGO:190259330.017
positive regulation of cytokine productionGO:000181920.017
regulation of cell activationGO:005086510.017
regulation of metal ion transportGO:001095940.017
neuroblast proliferationGO:000740520.017
b cell activationGO:004211320.017
macromolecule biosynthetic processGO:00090592270.017
modification dependent macromolecule catabolic processGO:004363230.017
regulation of developmental processGO:00507932470.017
positive regulation of cytoskeleton organizationGO:005149530.017
atp catabolic processGO:000620040.017
regulation of nitrogen compound metabolic processGO:00511712510.017
negative regulation of catabolic processGO:000989530.017
positive regulation of myeloid cell differentiationGO:004563920.017
regulation of reactive oxygen species metabolic processGO:200037720.017
regulation of i kappab kinase nf kappab signalingGO:004312240.017
embryonic organ developmentGO:00485683810.017
neuron neuron synaptic transmissionGO:000727010.017
regulation of multicellular organismal processGO:00512392770.017
negative regulation of cellular processGO:00485232830.017
sensory organ developmentGO:00074233930.017
positive regulation of translationGO:004572710.017
neurotransmitter transportGO:000683620.017
nuclear importGO:005117030.017
synaptic vesicle localizationGO:009747910.017
proteolysis involved in cellular protein catabolic processGO:005160330.017
system processGO:00030081850.017
cellular amino acid metabolic processGO:000652070.017
negative regulation of biological processGO:00485193040.017
regulation of protein catabolic processGO:004217610.017
negative regulation of cellular catabolic processGO:003133030.017
cellular protein catabolic processGO:004425740.017
chemosensory behaviorGO:000763510.016
rna localizationGO:000640340.016
regulation of circadian rhythmGO:004275240.016
amino acid transportGO:000686520.016
regulation of phGO:000688530.016
cell projection morphogenesisGO:00488582440.016
positive regulation of i kappab kinase nf kappab signalingGO:004312330.016
positive regulation of cellular processGO:00485222010.016
regulation of macromolecule biosynthetic processGO:00105562250.016
regulation of cell shapeGO:000836010.016
protein secretionGO:000930610.016
single organism metabolic processGO:00447102170.016
cellular aromatic compound metabolic processGO:00067252950.016
protein polymerizationGO:005125840.016
muscle structure developmentGO:00610611960.016
heart developmentGO:00075073130.016
response to external biotic stimulusGO:0043207970.016
neuron developmentGO:00486662620.016
establishment of localizationGO:00512342440.016
positive regulation of secretion by cellGO:190353210.016
positive regulation of secretionGO:005104710.016
ribonucleoside monophosphate catabolic processGO:000915840.016
organic cyclic compound biosynthetic processGO:19013622230.016
regulation of nucleotide catabolic processGO:003081120.016
regulation of cytoplasmic transportGO:190364940.016
response to biotic stimulusGO:0009607970.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
cell morphogenesisGO:00009022890.016
protein complex disassemblyGO:004324110.016
purine nucleoside monophosphate catabolic processGO:000912840.015
regulation of dendrite developmentGO:005077330.015
negative regulation of kinase activityGO:003367340.015
synaptic transmission cholinergicGO:000727140.015
regulation of protein ubiquitinationGO:003139630.015
regulation of neural precursor cell proliferationGO:200017730.015
regulation of signalingGO:00230512350.015
regulation of primary metabolic processGO:00800903110.015
neurotransmitter secretionGO:000726920.015
regulation of biosynthetic processGO:00098892500.015
tube morphogenesisGO:00352393490.015
central nervous system developmentGO:00074173870.015
multi organism processGO:00517041340.015
regulation of organ growthGO:004662030.015
inositol lipid mediated signalingGO:004801720.015
sequestering of metal ionGO:005123830.014
response to glucocorticoidGO:005138410.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.014
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.014
growthGO:00400071740.014
stem cell divisionGO:001714510.014
regulation of jak stat cascadeGO:004642530.014
macroautophagyGO:001623610.014
regulation of protein polymerizationGO:003227120.014
cellular response to molecule of bacterial originGO:007121930.014
meiotic cell cycle processGO:190304630.014
cell morphogenesis involved in differentiationGO:00009041950.014
meiotic nuclear divisionGO:000712640.014
cellular response to biotic stimulusGO:007121630.014
cellular nitrogen compound biosynthetic processGO:00442712180.014
heterocycle biosynthetic processGO:00181302150.014
positive regulation of cytosolic calcium ion concentrationGO:000720440.014
superoxide metabolic processGO:000680120.014
regulation of gtp catabolic processGO:003312420.014
intracellular signal transductionGO:0035556850.014
regulation of cell differentiationGO:00455951420.014
proteasomal protein catabolic processGO:001049820.014
regulation of gtpase activityGO:004308720.014
secondary metabolic processGO:001974830.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
positive regulation of blood circulationGO:190352420.013
vasculature developmentGO:00019442780.013
actin polymerization or depolymerizationGO:000815420.013
regulation of intracellular protein transportGO:003315730.013
positive regulation of dna metabolic processGO:005105410.013
membrane invaginationGO:001032410.013
compound eye developmentGO:004874920.013
protein acetylationGO:000647320.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
spermatid developmentGO:000728620.013
dicarboxylic acid transportGO:000683510.013
cellular response to lipopolysaccharideGO:007122230.013
cell morphogenesis involved in neuron differentiationGO:00486671630.013
regulation of response to extracellular stimulusGO:003210410.013
positive regulation of immune effector processGO:000269930.013
phagocytosis engulfmentGO:000691110.013
regulation of mrna processingGO:005068430.013
protein localization to plasma membraneGO:007265910.013
endosomal transportGO:001619720.013
somatic stem cell maintenanceGO:003501910.013
regulation of tube sizeGO:003515020.013
eye developmentGO:00016542770.013
cellular response to chemical stimulusGO:00708871570.013
positive regulation of map kinase activityGO:004340630.013
neuron projection developmentGO:00311751800.013
regulation of meiotic cell cycleGO:005144510.013
peptidyl lysine acetylationGO:001839420.013
positive regulation of jnk cascadeGO:004633030.013
regulation of oocyte developmentGO:006028130.013
intracellular mrna localizationGO:000829810.013
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.013
regulation of neurotransmitter transportGO:005158810.013
positive regulation of nucleotide catabolic processGO:003081310.013
regulation of carbohydrate metabolic processGO:000610940.013
rna metabolic processGO:00160702190.013
phosphatidylinositol 3 kinase signalingGO:001406520.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
blood vessel developmentGO:00015682460.013
actin filament based movementGO:003004810.012
positive regulation of nucleoside metabolic processGO:004597910.012
regulation of protein complex disassemblyGO:004324410.012
actin filament polymerizationGO:003004120.012
hormone transportGO:000991420.012
cell cycle arrestGO:000705010.012
response to other organismGO:0051707970.012
aromatic compound biosynthetic processGO:00194382170.012
internal peptidyl lysine acetylationGO:001839320.012
regulation of inflammatory responseGO:005072720.012
anterior posterior pattern specificationGO:00099521520.012
mononuclear cell proliferationGO:003294310.012
regulation of cellular biosynthetic processGO:00313262450.012
positive regulation of cell adhesionGO:004578510.012
cellular response to radiationGO:007147840.012
regulation of neurotransmitter secretionGO:004692810.012
female sex differentiationGO:004666040.012
protein dephosphorylationGO:000647030.012
protein heterooligomerizationGO:005129110.012
smooth muscle contractionGO:000693920.012
enzyme linked receptor protein signaling pathwayGO:00071671060.012
positive regulation of lymphocyte mediated immunityGO:000270810.012
response to monosaccharideGO:003428430.012
golgi vesicle transportGO:004819330.012
protein metabolic processGO:00195381830.012
regulation of protein depolymerizationGO:190187910.012
regulation of cellular protein catabolic processGO:190336210.012
positive regulation of cell divisionGO:005178120.012
hormone secretionGO:004687920.012
digestive tract morphogenesisGO:00485462310.012
regulation of blood pressureGO:000821710.012
neuromuscular synaptic transmissionGO:000727420.012
alcohol biosynthetic processGO:004616520.012
development of primary female sexual characteristicsGO:004654540.012
brain developmentGO:00074202930.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
regulation of response to nutrient levelsGO:003210710.012
fatty acid transportGO:001590810.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
regulation of neuronal synaptic plasticityGO:004816810.012
sensory perception of chemical stimulusGO:000760630.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
positive regulation of cell activationGO:005086710.012
sleepGO:003043110.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
olfactory lobe developmentGO:002198840.011
inner ear developmentGO:00488391260.011
negative regulation of synapse assemblyGO:005196420.011
regulation of sequestering of calcium ionGO:005128240.011
single organism biosynthetic processGO:0044711710.011
organism emergence from protective structureGO:007168440.011
ion transportGO:00068111140.011
regulation of transporter activityGO:003240920.011
carbohydrate homeostasisGO:003350010.011
activation of mapk activityGO:000018730.011
extrinsic apoptotic signaling pathwayGO:009719130.011
actin mediated cell contractionGO:007025210.011
head developmentGO:00603223030.011
response to uvGO:000941130.011
axon developmentGO:00615641660.011
calcium ion transport into cytosolGO:006040230.011
response to amino acidGO:004320020.011
phosphatidylinositol mediated signalingGO:004801520.011
axonogenesisGO:00074091520.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
locomotionGO:00400113130.011
response to corticosteroidGO:003196010.011
transportGO:00068102200.011
protein acylationGO:004354330.011
mitochondrion organizationGO:000700540.011
developmental programmed cell deathGO:001062340.011
phototransductionGO:000760220.011
embryonic organ morphogenesisGO:00485622740.011
negative regulation of mapk cascadeGO:004340940.011
cell cycle g1 s phase transitionGO:004484310.011
camera type eye developmentGO:00430102220.011
developmental growthGO:00485891660.011
protein depolymerizationGO:005126110.011
regulation of transmembrane transporter activityGO:002289820.011
striated muscle tissue developmentGO:00147061100.011
rna biosynthetic processGO:00327741810.011
astrocyte differentiationGO:004870810.011
positive regulation of gtp catabolic processGO:003312610.011
negative regulation of autophagyGO:001050710.011
regulation of nucleic acid templated transcriptionGO:19035062130.011
regulation of sodium ion transportGO:000202820.011
transcription dna templatedGO:00063511810.011
angiogenesisGO:00015251580.011
sequestering of calcium ionGO:005120830.011
regulation of protein bindingGO:004339330.011
single organism transportGO:00447652060.011
inorganic cation transmembrane transportGO:0098662500.011
maternal determination of anterior posterior axis embryoGO:000835840.011
phosphate containing compound metabolic processGO:00067961080.011
negative regulation of sequestering of calcium ionGO:005128340.011
cellular protein metabolic processGO:00442671290.011
internal protein amino acid acetylationGO:000647520.011
regulation of blood vessel sizeGO:005088020.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
cellular response to light stimulusGO:007148240.011
regulation of wound healingGO:006104120.011
sensory perception of painGO:001923310.011
response to bacteriumGO:0009617580.011
cytoplasm organizationGO:000702840.011
centrosome organizationGO:005129710.011
wound healingGO:0042060900.011
negative regulation of metabolic processGO:0009892860.011
female gonad developmentGO:000858540.011
neuron remodelingGO:001632210.010
double strand break repairGO:000630230.010
regulation of nucleobase containing compound metabolic processGO:00192192500.010
fertilizationGO:000956630.010
peptidyl serine modificationGO:001820920.010
cardiac atrium morphogenesisGO:000320920.010
protein homooligomerizationGO:005126030.010
cell migrationGO:00164772370.010
blood vessel morphogenesisGO:00485142160.010
nucleobase containing compound biosynthetic processGO:00346542050.010
germ line stem cell maintenanceGO:003071820.010
protein stabilizationGO:005082120.010
regulation of nucleocytoplasmic transportGO:004682220.010
regulation of cell developmentGO:00602841000.010
response to hexoseGO:000974630.010
cell killingGO:000190620.010
mechanosensory behaviorGO:000763820.010
response to nutrientGO:000758430.010
regulation of dendrite morphogenesisGO:004881430.010
somite developmentGO:0061053960.010
cellular monovalent inorganic cation homeostasisGO:003000420.010
response to topologically incorrect proteinGO:003596620.010
blood circulationGO:0008015870.010
sensory organ morphogenesisGO:00905962000.010
mitotic cytokinesisGO:000028130.010
establishment of protein localization to plasma membraneGO:009000210.010
cellular protein complex disassemblyGO:004362410.010
regulation of exocytosisGO:001715710.010
interspecies interaction between organismsGO:004441940.010
nucleoside monophosphate catabolic processGO:000912540.010
regulation of ion transmembrane transporter activityGO:003241220.010
ion transmembrane transportGO:0034220910.010
g1 s transition of mitotic cell cycleGO:000008210.010
negative regulation of leukocyte differentiationGO:190210610.010
gastrulationGO:00073692080.010
ear developmentGO:00435831270.010
nucleic acid templated transcriptionGO:00976591810.010
single organism localizationGO:19025782250.010
positive regulation of stem cell proliferationGO:200064810.010

il4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.049
nervous system diseaseDOID:86300.016
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
sensory system diseaseDOID:005015500.013
eye diseaseDOID:561400.013
eye and adnexa diseaseDOID:149200.013
musculoskeletal system diseaseDOID:1700.013
disease of metabolismDOID:001466700.012
organ system cancerDOID:005068600.012