Danio rerio

47 known processes

il8

interleukin 8

(Aliases: si:dkey-151b16.2)

il8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to lipopolysaccharideGO:007122230.736
cellular response to molecule of bacterial originGO:007121930.548
positive regulation of i kappab kinase nf kappab signalingGO:004312330.340
toll like receptor signaling pathwayGO:000222440.303
positive regulation of defense responseGO:003134990.285
positive regulation of inflammatory responseGO:005072910.279
maintenance of locationGO:005123540.277
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.269
response to ketoneGO:190165410.230
response to amino acidGO:004320020.223
cellular response to biotic stimulusGO:007121630.217
positive regulation of lipid metabolic processGO:004583410.211
regulation of multicellular organism growthGO:004001440.210
response to drugGO:004249330.179
regulation of proteolysisGO:0030162240.174
regulation of intracellular protein transportGO:003315730.173
regulation of nucleocytoplasmic transportGO:004682220.170
reactive oxygen species metabolic processGO:007259360.170
regulation of protein import into nucleusGO:004230620.168
negative regulation of secretionGO:005104820.168
positive regulation of response to external stimulusGO:003210390.167
regulation of protein localization to nucleusGO:190018020.165
nucleocytoplasmic transportGO:000691340.164
lipid storageGO:001991510.162
multicellular organism growthGO:003526440.159
protein targeting to nucleusGO:004474430.159
regulation of inflammatory responseGO:005072720.157
cell motilityGO:00488702440.157
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.155
cellular response to external stimulusGO:007149620.146
larval developmentGO:000216420.139
regulation of reactive oxygen species metabolic processGO:200037720.132
negative regulation of protein phosphorylationGO:000193340.130
regulation of cytokine productionGO:000181730.126
response to bacteriumGO:0009617580.126
response to corticosteroidGO:003196010.124
protein import into nucleusGO:000660630.122
protein importGO:001703830.120
single organism nuclear importGO:190259330.120
carboxylic acid metabolic processGO:0019752220.120
nuclear importGO:005117030.118
i kappab kinase nf kappab signalingGO:000724940.116
regulation of endopeptidase activityGO:0052548230.113
regulation of i kappab kinase nf kappab signalingGO:004312240.113
positive regulation of cytokine productionGO:000181920.112
response to other organismGO:0051707970.111
dicarboxylic acid transportGO:000683510.111
regulation of multicellular organismal processGO:00512392770.110
protein complex localizationGO:003150310.110
immune system processGO:00023762410.108
regulation of establishment of protein localizationGO:007020140.108
regulation of response to stimulusGO:00485832690.105
regulation of protein targetingGO:190353320.104
response to external stimulusGO:00096052640.101
regulation of protein transportGO:005122330.099
apoptotic processGO:00069151160.097
protein localization to nucleusGO:003450430.097
positive regulation of transportGO:005105020.096
cellular ketone metabolic processGO:0042180110.095
reactive nitrogen species metabolic processGO:200105700.093
nuclear transportGO:005116940.090
establishment of protein localization to organelleGO:007259440.090
response to glucocorticoidGO:005138410.089
regulation of cytoplasmic transportGO:190364940.087
vasculature developmentGO:00019442780.086
cell migrationGO:00164772370.086
positive regulation of cell adhesionGO:004578510.086
response to alkaloidGO:004327920.085
negative regulation of secretion by cellGO:190353120.084
zymogen activationGO:003163830.084
regulation of muscle contractionGO:000693730.084
cell surface receptor signaling pathwayGO:00071663250.083
protein secretionGO:000930610.083
cell substrate adhesionGO:003158940.082
cellular response to lipidGO:0071396390.080
response to nutrientGO:000758430.080
positive regulation of immune effector processGO:000269930.079
transmembrane transportGO:00550851200.079
regulation of cysteine type endopeptidase activityGO:2000116210.078
regulation of transcription dna templatedGO:00063552130.077
amino acid transportGO:000686520.077
calcium ion importGO:007050940.076
cytokine mediated signaling pathwayGO:001922170.073
anion transportGO:0006820380.071
regulation of cell activationGO:005086510.071
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.071
response to steroid hormoneGO:0048545350.070
cellular carbohydrate metabolic processGO:004426240.069
response to vitaminGO:003327330.069
regulation of cell deathGO:00109411030.069
ion transmembrane transportGO:0034220910.068
regulation of defense responseGO:0031347140.068
single organism transportGO:00447652060.068
angiogenesisGO:00015251580.066
positive regulation of jnk cascadeGO:004633030.066
programmed cell deathGO:00125011190.065
regulation of glucose transportGO:001082710.064
neuron neuron synaptic transmissionGO:000727010.064
collagen metabolic processGO:003296320.063
regulation of cellular ketone metabolic processGO:001056570.063
regulation of extrinsic apoptotic signaling pathwayGO:200123630.063
digestive tract morphogenesisGO:00485462310.063
locomotionGO:00400113130.063
cation transportGO:0006812810.062
nitric oxide metabolic processGO:004620920.062
positive regulation of cellular amino acid metabolic processGO:004576400.061
actin mediated cell contractionGO:007025210.061
positive regulation of response to woundingGO:190303650.060
muscle cell developmentGO:00550011150.060
blood vessel developmentGO:00015682460.059
nitric oxide biosynthetic processGO:000680920.058
positive regulation of stress activated mapk cascadeGO:003287430.058
response to molecule of bacterial originGO:0002237140.058
cellular response to hypoxiaGO:007145610.057
positive regulation of programmed cell deathGO:0043068290.057
multicellular organismal metabolic processGO:004423620.057
negative regulation of protein kinase activityGO:000646940.056
enzyme linked receptor protein signaling pathwayGO:00071671060.056
agingGO:000756820.056
lipid catabolic processGO:001604240.054
negative regulation of kinase activityGO:003367340.054
positive regulation of secretion by cellGO:190353210.054
regulation of glucose importGO:004632410.054
muscle organ developmentGO:00075171010.053
fatty acid biosynthetic processGO:000663340.053
positive regulation of catabolic processGO:000989640.053
single organism metabolic processGO:00447102170.053
cation transmembrane transportGO:0098655650.053
proteolysisGO:0006508380.052
cell matrix adhesionGO:000716040.052
blood vessel morphogenesisGO:00485142160.052
regulation of cellular macromolecule biosynthetic processGO:20001122220.052
lipid homeostasisGO:005508830.051
peptide transportGO:001583310.051
regulation of carbohydrate metabolic processGO:000610940.051
ion transportGO:00068111140.051
hemopoiesisGO:00300971830.050
tube morphogenesisGO:00352393490.050
multicellular organismal macromolecule metabolic processGO:004425920.050
specification of symmetryGO:00097992040.050
positive regulation of innate immune responseGO:004508980.050
regulation of nitrogen compound metabolic processGO:00511712510.049
production of molecular mediator of immune responseGO:000244020.049
regulation of cell substrate adhesionGO:001081010.049
cellular response to organic cyclic compoundGO:0071407380.049
regulation of metal ion transportGO:001095940.049
cellular response to extracellular stimulusGO:003166820.049
negative regulation of cell deathGO:0060548600.049
negative regulation of cellular processGO:00485232830.049
negative regulation of catabolic processGO:000989530.049
glucose importGO:004632320.049
sensory perception of painGO:001923310.049
wound healingGO:0042060900.048
amine metabolic processGO:000930820.048
positive regulation of cellular catabolic processGO:003133130.048
organonitrogen compound metabolic processGO:1901564740.048
autophagyGO:000691440.048
androgen metabolic processGO:000820920.047
regulation of cell communicationGO:00106462320.047
response to biotic stimulusGO:0009607970.047
developmental growthGO:00485891660.046
female sex differentiationGO:004666040.046
regulation of rna metabolic processGO:00512522240.045
regulation of cellular amino acid metabolic processGO:000652100.045
regulation of cell shapeGO:000836010.045
gastrulationGO:00073692080.045
alcohol biosynthetic processGO:004616520.045
regulation of cellular amine metabolic processGO:003323800.045
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.045
regulation of hormone secretionGO:004688320.045
response to lipidGO:0033993600.045
cellular amine metabolic processGO:004410620.044
embryonic organ developmentGO:00485683810.044
regulation of developmental processGO:00507932470.044
cellular response to hormone stimulusGO:0032870390.044
digestive system developmentGO:00551232890.044
response to external biotic stimulusGO:0043207970.043
system processGO:00030081850.043
cellular nitrogen compound metabolic processGO:00346412900.043
regulation of signal transductionGO:00099662250.043
cellular response to nutrient levelsGO:003166920.043
organic acid metabolic processGO:0006082310.043
deathGO:00162651210.042
oxoacid metabolic processGO:0043436310.042
embryonic heart tube developmentGO:00350501330.042
regulation of protein catabolic processGO:004217610.042
rna biosynthetic processGO:00327741810.042
neuron developmentGO:00486662620.042
chemical homeostasisGO:0048878490.042
regulation of programmed cell deathGO:00430671010.041
gtp metabolic processGO:004603940.041
neutrophil migrationGO:1990266100.040
determination of bilateral symmetryGO:00098552040.040
regulation of production of molecular mediator of immune responseGO:000270010.040
cellular protein metabolic processGO:00442671290.040
fatty acid transportGO:001590810.040
positive regulation of cellular component biogenesisGO:004408930.039
regulation of biological qualityGO:00650082630.039
positive regulation of secretionGO:005104710.039
regulation of rna biosynthetic processGO:20011412130.039
positive regulation of cell activationGO:005086710.039
negative regulation of multicellular organismal processGO:0051241690.039
positive regulation of cell cycleGO:004578730.038
nitrogen compound metabolic processGO:00068073190.038
multi organism processGO:00517041340.038
regulation of lipase activityGO:006019120.038
phagocytosisGO:000690930.038
reactive oxygen species biosynthetic processGO:190340910.038
response to abiotic stimulusGO:00096281220.037
regulation of catalytic activityGO:0050790550.037
positive regulation of cellular amine metabolic processGO:003324000.037
positive regulation of neuron apoptotic processGO:004352510.037
positive regulation of nitrogen compound metabolic processGO:0051173690.037
development of primary female sexual characteristicsGO:004654540.036
response to carbohydrateGO:000974330.036
hydrogen peroxide metabolic processGO:004274320.035
regulation of bindingGO:005109830.035
cellular response to oxygen levelsGO:007145310.035
calcium ion transport into cytosolGO:006040230.035
cell deathGO:00082191210.035
innate immune response activating signal transductionGO:000275850.034
cytosolic calcium ion transportGO:006040130.034
small molecule biosynthetic processGO:0044283160.034
inflammatory responseGO:000695480.034
positive regulation of lymphocyte mediated immunityGO:000270810.034
positive regulation of map kinase activityGO:004340630.034
gtp catabolic processGO:000618420.034
regulation of wound healingGO:006104120.034
regulation of primary metabolic processGO:00800903110.034
response to stressGO:00069502630.034
regulation of peptidyl tyrosine phosphorylationGO:005073010.034
positive regulation of cytosolic calcium ion concentrationGO:000720440.034
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.034
cellular response to chemical stimulusGO:00708871570.034
positive regulation of hydrolase activityGO:0051345130.034
response to vitamin b3GO:003355220.033
peptidyl serine phosphorylationGO:001810510.033
endocrine processGO:005088620.033
morphogenesis of an epitheliumGO:00020093330.033
positive regulation of lipase activityGO:006019310.033
positive regulation of response to stimulusGO:0048584800.032
response to lipopolysaccharideGO:0032496130.032
negative regulation of programmed cell deathGO:0043069580.032
regulation of actin filament based movementGO:190311510.032
growthGO:00400071740.032
lymphocyte proliferationGO:004665110.031
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.031
inositol lipid mediated signalingGO:004801720.031
inorganic ion transmembrane transportGO:0098660570.031
tyrosine phosphorylation of stat proteinGO:000726010.031
hematopoietic or lymphoid organ developmentGO:00485341910.030
regulation of molecular functionGO:0065009700.030
developmental programmed cell deathGO:001062340.030
regulation of chronic inflammatory responseGO:000267610.030
organic substance biosynthetic processGO:19015762890.030
epithelial cell morphogenesisGO:000338220.030
calcium ion homeostasisGO:0055074190.030
regulation of response to nutrient levelsGO:003210710.030
immunoglobulin mediated immune responseGO:001606430.030
small molecule metabolic processGO:0044281770.030
negative regulation of biological processGO:00485193040.029
estrogen metabolic processGO:000821020.029
cellular response to endogenous stimulusGO:0071495680.029
regulation of lipid transportGO:003236840.029
leukocyte proliferationGO:007066110.029
localization of cellGO:00516742440.029
positive regulation of catalytic activityGO:0043085250.029
epithelial cell differentiationGO:00308551160.029
regulation of localizationGO:00328791040.029
female gonad developmentGO:000858540.029
regulation of hydrolase activityGO:0051336280.029
nik nf kappab signalingGO:003806110.028
negative regulation of protein processingGO:0010955100.028
cellular response to starvationGO:000926710.028
cellular macromolecule metabolic processGO:00442603910.028
lipid metabolic processGO:0006629520.028
positive regulation of neuron deathGO:190121610.028
hindbrain developmentGO:0030902910.028
signal transductionGO:00071654550.028
regulation of ion transmembrane transportGO:0034765180.028
response to organic cyclic compoundGO:0014070510.028
cellular biosynthetic processGO:00442492860.027
epithelial tube morphogenesisGO:00605621480.027
regulation of cardiac muscle cell contractionGO:008600410.027
aromatic compound biosynthetic processGO:00194382170.027
response to oxygen containing compoundGO:1901700550.027
nuclear migrationGO:000709730.027
gland developmentGO:00487321430.027
intracellular signal transductionGO:0035556850.027
transportGO:00068102200.027
protein localization to plasma membraneGO:007265910.026
immune system developmentGO:00025201910.026
hormone secretionGO:004687920.026
myotube cell developmentGO:0014904350.026
stem cell proliferationGO:007208940.026
defense responseGO:0006952470.026
negative regulation of cytokine productionGO:000181810.026
actin filament based processGO:0030029640.026
organic cyclic compound metabolic processGO:19013603010.026
cognitionGO:005089010.026
cellular response to xenobiotic stimulusGO:0071466350.026
regulation of nucleic acid templated transcriptionGO:19035062130.026
glycerolipid biosynthetic processGO:004501710.026
adult behaviorGO:003053420.025
hormone transportGO:000991420.025
organic cyclic compound biosynthetic processGO:19013622230.025
digestive tract developmentGO:00485652650.025
positive regulation of leukocyte mediated immunityGO:000270510.025
response to chemicalGO:00422213200.025
positive regulation of cellular metabolic processGO:0031325940.025
generation of neuronsGO:00486993850.025
regulation of apoptotic processGO:0042981980.025
eye developmentGO:00016542770.025
cellular lipid metabolic processGO:0044255360.025
guanosine containing compound catabolic processGO:190106920.025
glial cell proliferationGO:001400940.025
inorganic cation transmembrane transportGO:0098662500.025
cell proliferationGO:0008283800.025
regulation of response to cytokine stimulusGO:006075930.025
regulation of cardiac muscle contractionGO:005511720.024
axon developmentGO:00615641660.024
negative regulation of protein transportGO:005122430.024
mononuclear cell proliferationGO:003294310.024
nucleic acid metabolic processGO:00903042440.024
cellular response to drugGO:003569010.024
sodium ion importGO:009736930.024
positive regulation of protein kinase b signalingGO:005189710.024
biosynthetic processGO:00090582940.024
ameboidal type cell migrationGO:00016671430.024
cellular response to oxygen containing compoundGO:1901701200.024
b cell mediated immunityGO:001972430.024
regulation of nucleobase containing compound metabolic processGO:00192192500.024
single organism localizationGO:19025782250.023
response to endogenous stimulusGO:0009719830.023
peptidyl serine modificationGO:001820920.023
regulation of blood circulationGO:1903522320.023
regulation of jun kinase activityGO:004350630.023
regulation of gtpase activityGO:004308720.023
regulation of protein bindingGO:004339330.023
regulation of anatomical structure morphogenesisGO:00226031300.023
tissue remodelingGO:004877140.023
striated muscle cell developmentGO:00550021080.023
negative regulation of locomotionGO:0040013180.023
nucleobase containing compound biosynthetic processGO:00346542050.023
cellular response to organic substanceGO:00713101050.023
regulation of collagen metabolic processGO:001071220.023
protein kinase b signalingGO:004349190.022
protein metabolic processGO:00195381830.022
regulation of striated muscle contractionGO:000694220.022
negative regulation of hormone secretionGO:004688820.022
cellular response to organonitrogen compoundGO:007141750.022
extrinsic apoptotic signaling pathwayGO:009719130.022
muscle structure developmentGO:00610611960.022
apoptotic signaling pathwayGO:0097190230.022
muscle contractionGO:0006936180.022
establishment of localizationGO:00512342440.022
myotube differentiationGO:0014902450.022
regulation of peptidase activityGO:0052547230.022
regulation of macromolecule metabolic processGO:00602553170.022
negative regulation of mapk cascadeGO:004340940.022
ras protein signal transductionGO:000726570.022
leukocyte chemotaxisGO:0030595120.022
cellular amino acid metabolic processGO:000652070.021
regulation of multicellular organismal developmentGO:20000262230.021
cell migration involved in gastrulationGO:0042074790.021
positive regulation of cell substrate adhesionGO:001081110.021
negative regulation of protein serine threonine kinase activityGO:007190120.021
cellular response to decreased oxygen levelsGO:003629410.021
sarcomere organizationGO:0045214260.021
guanosine containing compound metabolic processGO:190106840.021
macromolecule modificationGO:00434121110.021
regulation of dna replicationGO:000627530.021
developmental growth involved in morphogenesisGO:0060560860.021
regulation of cellular carbohydrate metabolic processGO:001067540.021
positive regulation of apoptotic signaling pathwayGO:200123510.021
regulation of metabolic processGO:00192223590.021
stem cell differentiationGO:00488631170.021
regulation of signalingGO:00230512350.021
response to arsenic containing substanceGO:004668550.021
long chain fatty acid biosynthetic processGO:004275910.021
regulation of nucleotide catabolic processGO:003081120.020
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.020
positive regulation of multicellular organismal processGO:0051240520.020
positive regulation of nucleotide catabolic processGO:003081310.020
muscle tissue developmentGO:00605371100.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
positive regulation of biosynthetic processGO:0009891680.020
positive regulation of macromolecule metabolic processGO:0010604930.020
response to organic substanceGO:00100331530.020
insulin like growth factor receptor signaling pathwayGO:004800940.020
regulation of response to oxidative stressGO:190288220.020
positive regulation of wound healingGO:009030310.020
cellular response to prostaglandin stimulusGO:007137930.020
multicellular organismal response to stressGO:003355520.020
peripheral nervous system developmentGO:0007422550.020
cellular hormone metabolic processGO:0034754190.020
positive regulation of chronic inflammatory responseGO:000267810.020
embryo development ending in birth or egg hatchingGO:00097922710.020
regulation of response to stressGO:0080134360.020
negative regulation of map kinase activityGO:004340720.020
cellular response to stressGO:0033554620.020
regulation of response to extracellular stimulusGO:003210410.020
exocrine system developmentGO:0035272280.019
pyruvate metabolic processGO:000609010.019
striated muscle contractionGO:0006941120.019
positive regulation of gtp catabolic processGO:003312610.019
gene expressionGO:00104672520.019
tissue migrationGO:0090130370.019
transcription dna templatedGO:00063511810.019
regulation of intracellular signal transductionGO:1902531570.019
kupffer s vesicle developmentGO:0070121500.019
response to glucoseGO:000974930.019
g1 s transition of mitotic cell cycleGO:000008210.019
fat soluble vitamin biosynthetic processGO:004236220.019
phosphatidylinositol mediated signalingGO:004801520.019
regulation of growthGO:0040008420.019
negative regulation of apoptotic processGO:0043066550.019
neurological system processGO:0050877620.019
cellular nitrogen compound biosynthetic processGO:00442712180.019
multicellular organismal homeostasisGO:0048871290.019
defense response to bacteriumGO:0042742220.019
adherens junction organizationGO:003433240.019
cytokine metabolic processGO:004210710.018
nucleobase containing compound metabolic processGO:00061392740.018
regulation of fatty acid metabolic processGO:001921710.018
glucose homeostasisGO:004259310.018
lipid biosynthetic processGO:0008610220.018
establishment of localization in cellGO:0051649770.018
positive regulation of signal transductionGO:0009967560.018
neuroblast proliferationGO:000740520.018
heterocycle biosynthetic processGO:00181302150.018
maintenance of gastrointestinal epitheliumGO:003027770.018
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.018
determination of left right symmetryGO:00073681790.018
cytokinesisGO:000091030.018
positive regulation of cellular processGO:00485222010.018
single organism biosynthetic processGO:0044711710.018
skeletal muscle organ developmentGO:0060538780.018
regulation of gene expressionGO:00104682650.018
sensory perceptionGO:0007600390.018
regulation of sequestering of calcium ionGO:005128240.018
regulation of autophagyGO:001050630.018
regulation of cellular response to oxidative stressGO:190040720.018
signal transduction in absence of ligandGO:003803410.018
response to nitrogen compoundGO:1901698190.018
long chain fatty acid metabolic processGO:000167610.017
cardiac muscle cell contractionGO:008600310.017
response to inorganic substanceGO:0010035380.017
positive regulation of biological processGO:00485182530.017
negative regulation of response to cytokine stimulusGO:006076120.017
multi organism cellular processGO:004476420.017
innate immune responseGO:0045087130.017
vasculogenesisGO:0001570410.017
actin filament based movementGO:003004810.017
immune responseGO:0006955280.017
immunoglobulin productionGO:000237710.017
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.017
regulation of cellular metabolic processGO:00313233200.017
ovulation cycle processGO:002260220.017
neuron differentiationGO:00301823530.017
b cell activationGO:004211320.017
regulation of photoreceptor cell differentiationGO:004653220.017
negative regulation of proteolysisGO:0045861100.017
regulation of tyrosine phosphorylation of stat proteinGO:004250910.017
sprouting angiogenesisGO:0002040530.017
organic anion transportGO:0015711150.017
negative regulation of protein complex assemblyGO:003133310.016
body morphogenesisGO:0010171160.016
positive regulation of immune responseGO:0050778110.016
regulation of behaviorGO:0050795240.016
regulation of innate immune responseGO:0045088110.016
response to woundingGO:00096111160.016
cellular response to nitrogen compoundGO:190169960.016
sensory perception of smellGO:000760820.016
regulation of cellular protein metabolic processGO:0032268520.016
regulation of calcium ion transportGO:005192420.016
positive regulation of gliogenesisGO:001401520.016
regulation of system processGO:0044057400.016
type i interferon productionGO:003260620.016
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.016
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.016
regulation of erk1 and erk2 cascadeGO:007037240.016
phagocytosis engulfmentGO:000691110.016
metal ion transportGO:0030001580.016
negative regulation of cellular protein metabolic processGO:0032269160.016
acylglycerol homeostasisGO:005509020.016
macromolecule biosynthetic processGO:00090592270.016

il8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.032
cancerDOID:16200.032
organ system cancerDOID:005068600.032
disease of anatomical entityDOID:700.026
nervous system diseaseDOID:86300.023
eye diseaseDOID:561400.019
eye and adnexa diseaseDOID:149200.019
sensory system diseaseDOID:005015500.019
disease of metabolismDOID:001466700.017