Danio rerio

0 known processes

hic1l

hypermethylated in cancer 1 like

(Aliases: hic1,zgc:153128,hzp1,wu:fa03g10,zfHIC1a,MGC153128)

hic1l biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.157
modification dependent protein catabolic processGO:001994130.082
modification dependent macromolecule catabolic processGO:004363230.077
establishment of protein localization to organelleGO:007259440.076
agingGO:000756820.073
cellular protein catabolic processGO:004425740.073
ubiquitin dependent protein catabolic processGO:000651130.071
lipid storageGO:001991510.068
maintenance of locationGO:005123540.064
meiotic nuclear divisionGO:000712640.060
proteolysis involved in cellular protein catabolic processGO:005160330.060
signal transductionGO:00071654550.054
single organism metabolic processGO:00447102170.053
regulation of protein catabolic processGO:004217610.051
central nervous system developmentGO:00074173870.050
nuclear transportGO:005116940.049
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.048
multicellular organism growthGO:003526440.048
response to topologically incorrect proteinGO:003596620.047
proteasomal protein catabolic processGO:001049820.046
regulation of primary metabolic processGO:00800903110.043
protein localization to nucleusGO:003450430.042
neuron developmentGO:00486662620.042
protein targeting to nucleusGO:004474430.042
meiotic chromosome segregationGO:004513230.042
positive regulation of transportGO:005105020.041
positive regulation of protein complex assemblyGO:003133420.041
endosomal transportGO:001619720.040
regulation of protein modification by small protein conjugation or removalGO:190332030.040
cellular macromolecule metabolic processGO:00442603910.039
nucleocytoplasmic transportGO:000691340.038
spindle assemblyGO:005122520.036
golgi vesicle transportGO:004819330.036
negative regulation of protein phosphorylationGO:000193340.036
cognitionGO:005089010.036
protein import into nucleusGO:000660630.035
single organism nuclear importGO:190259330.034
establishment of localizationGO:00512342440.034
positive regulation of catabolic processGO:000989640.033
nucleobase containing compound metabolic processGO:00061392740.033
autophagyGO:000691440.033
regulation of metabolic processGO:00192223590.032
regulation of hormone secretionGO:004688320.032
nuclear importGO:005117030.031
cellular component movementGO:00069283350.031
transportGO:00068102200.031
regulation of signal transductionGO:00099662250.031
embryo development ending in birth or egg hatchingGO:00097922710.031
sensory organ developmentGO:00074233930.031
regulation of multicellular organism growthGO:004001440.030
amine metabolic processGO:000930820.030
regulation of protein ubiquitinationGO:003139630.030
regulation of circadian rhythmGO:004275240.030
meiotic cell cycle processGO:190304630.030
system processGO:00030081850.030
response to stressGO:00069502630.029
cell surface receptor signaling pathwayGO:00071663250.029
positive regulation of canonical wnt signaling pathwayGO:009026340.029
regulation of cellular metabolic processGO:00313233200.029
intracellular signal transductionGO:0035556850.029
regulation of rna metabolic processGO:00512522240.028
fertilizationGO:000956630.027
protein importGO:001703830.027
chemosensory behaviorGO:000763510.027
cellular amine metabolic processGO:004410620.027
actin polymerization or depolymerizationGO:000815420.027
camera type eye developmentGO:00430102220.027
tube morphogenesisGO:00352393490.027
digestive system developmentGO:00551232890.027
regulation of multicellular organismal processGO:00512392770.026
regulation of cell communicationGO:00106462320.026
positive regulation of cellular component biogenesisGO:004408930.026
neuron differentiationGO:00301823530.026
regulation of protein complex assemblyGO:004325430.025
regulation of peptidyl tyrosine phosphorylationGO:005073010.025
negative regulation of tor signalingGO:003200720.025
locomotionGO:00400113130.025
translational initiationGO:000641330.025
cellular response to extracellular stimulusGO:003166820.025
organic cyclic compound biosynthetic processGO:19013622230.025
positive regulation of cytokine productionGO:000181920.025
single organism organelle organizationGO:19025891990.024
positive regulation of cellular catabolic processGO:003133130.024
adult behaviorGO:003053420.024
head developmentGO:00603223030.024
regulation of biological qualityGO:00650082630.024
regulation of biosynthetic processGO:00098892500.024
generation of neuronsGO:00486993850.024
nitrogen compound metabolic processGO:00068073190.024
cellular response to external stimulusGO:007149620.024
positive regulation of immune effector processGO:000269930.024
nucleic acid templated transcriptionGO:00976591810.024
organelle organizationGO:00069962270.023
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.023
negative regulation of map kinase activityGO:004340720.023
cellular component disassemblyGO:002241110.023
regulation of signalingGO:00230512350.023
i kappab kinase nf kappab signalingGO:000724940.023
regulation of bindingGO:005109830.023
regulation of macromolecule biosynthetic processGO:00105562250.023
regulation of cellular amino acid metabolic processGO:000652100.023
protein metabolic processGO:00195381830.023
positive regulation of biological processGO:00485182530.022
vacuolar transportGO:000703420.022
circadian sleep wake cycleGO:004274520.022
regulation of cytokine productionGO:000181730.022
digestive tract developmentGO:00485652650.022
female sex differentiationGO:004666040.022
response to drugGO:004249330.022
muscle structure developmentGO:00610611960.022
apoptotic processGO:00069151160.022
immune system processGO:00023762410.021
negative regulation of protein kinase activityGO:000646940.021
rna localizationGO:000640340.021
rna metabolic processGO:00160702190.021
cell projection organizationGO:00300302840.021
cell deathGO:00082191210.021
protein dephosphorylationGO:000647030.021
cell migrationGO:00164772370.021
protein polyubiquitinationGO:000020940.021
organic substance biosynthetic processGO:19015762890.020
response to chemicalGO:00422213200.020
eye developmentGO:00016542770.020
regulation of jak stat cascadeGO:004642530.020
stem cell proliferationGO:007208940.020
positive regulation of cell cycleGO:004578730.020
regulation of cell activationGO:005086510.020
negative regulation of kinase activityGO:003367340.020
protein modification processGO:00362111000.020
cellular response to lipopolysaccharideGO:007122230.020
regionalizationGO:00030022740.020
internal protein amino acid acetylationGO:000647520.020
positive regulation of secretionGO:005104710.020
extrinsic apoptotic signaling pathwayGO:009719130.019
regulation of extrinsic apoptotic signaling pathwayGO:200123630.019
regulation of cellular protein catabolic processGO:190336210.019
female gonad developmentGO:000858540.019
protein polymerizationGO:005125840.019
regulation of establishment of protein localizationGO:007020140.019
regulation of dendrite morphogenesisGO:004881430.019
positive regulation of secretion by cellGO:190353210.019
regulation of i kappab kinase nf kappab signalingGO:004312240.019
regulation of cellular amine metabolic processGO:003323800.019
deathGO:00162651210.019
aromatic compound biosynthetic processGO:00194382170.019
negative regulation of signal transductionGO:0009968940.019
cellular macromolecule biosynthetic processGO:00346452240.019
biosynthetic processGO:00090582940.019
regulation of exocytosisGO:001715710.019
cell part morphogenesisGO:00329902460.019
cell projection morphogenesisGO:00488582440.018
single fertilizationGO:000733830.018
positive regulation of protein polymerizationGO:003227320.018
cellular ketone metabolic processGO:0042180110.018
negative regulation of cellular processGO:00485232830.018
cellular response to starvationGO:000926710.018
organic cyclic compound metabolic processGO:19013603010.018
cellular response to nutrient levelsGO:003166920.018
gastrulationGO:00073692080.018
nucleobase containing compound biosynthetic processGO:00346542050.018
regulation of cellular ketone metabolic processGO:001056570.018
single organism transportGO:00447652060.018
cellular component morphogenesisGO:00329893360.018
regulation of protein localization to nucleusGO:190018020.018
regulation of reproductive processGO:200024140.018
cellular protein modification processGO:00064641000.018
organonitrogen compound metabolic processGO:1901564740.018
negative regulation of response to stimulusGO:00485851040.018
macroautophagyGO:001623610.017
skeletal muscle organ developmentGO:0060538780.017
positive regulation of cellular processGO:00485222010.017
hematopoietic or lymphoid organ developmentGO:00485341910.017
heterocycle metabolic processGO:00464832900.017
regulation of skeletal muscle tissue developmentGO:004864140.017
cellular response to biotic stimulusGO:007121630.017
locomotor rhythmGO:004547530.017
enzyme linked receptor protein signaling pathwayGO:00071671060.017
negative regulation of signalingGO:0023057960.017
developmental growthGO:00485891660.017
negative regulation of cytoplasmic transportGO:190365020.017
exocytosisGO:000688710.017
cellular carbohydrate metabolic processGO:004426240.017
regulation of cytoplasmic transportGO:190364940.017
negative regulation of protein serine threonine kinase activityGO:007190120.017
regulation of protein targetingGO:190353320.017
positive regulation of cellular amine metabolic processGO:003324000.017
sleepGO:003043110.017
response to external stimulusGO:00096052640.016
positive regulation of map kinase activityGO:004340630.016
single organism localizationGO:19025782250.016
mitochondrion organizationGO:000700540.016
lateral inhibitionGO:004633110.016
programmed cell deathGO:00125011190.016
gene expressionGO:00104672520.016
tissue remodelingGO:004877140.016
growthGO:00400071740.016
regulation of reactive oxygen species metabolic processGO:200037720.016
rna biosynthetic processGO:00327741810.016
muscle organ developmentGO:00075171010.015
long chain fatty acid metabolic processGO:000167610.015
sensory organ morphogenesisGO:00905962000.015
nuclear exportGO:005116810.015
compound eye developmentGO:004874920.015
peptidyl lysine acetylationGO:001839420.015
response to corticosteroidGO:003196010.015
cellular protein metabolic processGO:00442671290.015
phagocytosisGO:000690930.015
actin filament polymerizationGO:003004120.015
regulation of response to stimulusGO:00485832690.015
cellular aromatic compound metabolic processGO:00067252950.015
regulation of cellular macromolecule biosynthetic processGO:20001122220.015
cellular response to chemical stimulusGO:00708871570.015
cell motilityGO:00488702440.015
cellular response to molecule of bacterial originGO:007121930.015
regulation of programmed cell deathGO:00430671010.015
circadian sleep wake cycle sleepGO:005080210.015
positive regulation of striated muscle tissue developmentGO:004584410.015
brain developmentGO:00074202930.015
spermatid developmentGO:000728620.015
regulation of steroid hormone secretionGO:200083110.015
immune system developmentGO:00025201910.015
regulation of synaptic plasticityGO:004816710.015
peptidyl serine phosphorylationGO:001810510.015
neuroblast proliferationGO:000740520.015
cellular nitrogen compound metabolic processGO:00346412900.015
internal peptidyl lysine acetylationGO:001839320.015
macromolecule localizationGO:0033036540.015
protein complex disassemblyGO:004324110.015
regulation of macromolecule metabolic processGO:00602553170.015
negative regulation of catabolic processGO:000989530.015
muscle tissue developmentGO:00605371100.015
protein secretionGO:000930610.015
regulation of stem cell proliferationGO:007209120.015
transcription dna templatedGO:00063511810.015
oxoacid metabolic processGO:0043436310.014
regulation of apoptotic processGO:0042981980.014
cell morphogenesisGO:00009022890.014
negative regulation of cellular catabolic processGO:003133030.014
regulation of meiotic cell cycleGO:005144510.014
hormone secretionGO:004687920.014
gtp catabolic processGO:000618420.014
spermatid differentiationGO:004851520.014
response to hydrogen peroxideGO:004254230.014
regulation of cell shapeGO:000836010.014
g1 s transition of mitotic cell cycleGO:000008210.014
multi organism processGO:00517041340.014
hemopoiesisGO:00300971830.014
negative regulation of biological processGO:00485193040.014
regulation of nucleocytoplasmic transportGO:004682220.014
positive regulation of exocytosisGO:004592110.014
regulation of protein import into nucleusGO:004230620.014
endocrine hormone secretionGO:006098620.014
entrainment of circadian clockGO:000964920.014
regulation of developmental processGO:00507932470.014
protein acylationGO:004354330.014
response to organic substanceGO:00100331530.014
morphogenesis of an epitheliumGO:00020093330.014
female meiotic divisionGO:000714320.014
heart developmentGO:00075073130.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
carboxylic acid metabolic processGO:0019752220.014
membrane fusionGO:006102520.014
macromolecule modificationGO:00434121110.014
centrosome cycleGO:000709810.014
regulation of transcription dna templatedGO:00063552130.014
positive regulation of lymphocyte mediated immunityGO:000270810.014
steroid hormone secretionGO:003592910.014
macromolecular complex disassemblyGO:003298410.014
vasculature developmentGO:00019442780.013
regulation of gene expressionGO:00104682650.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.013
regulation of erk1 and erk2 cascadeGO:007037240.013
lamellipodium assemblyGO:003003210.013
somatic muscle developmentGO:000752540.013
leukocyte proliferationGO:007066110.013
regulation of nitrogen compound metabolic processGO:00511712510.013
regulation of localizationGO:00328791040.013
catechol containing compound metabolic processGO:000971220.013
regulation of dendrite developmentGO:005077330.013
interspecies interaction between organismsGO:004441940.013
synaptic growth at neuromuscular junctionGO:005112420.013
development of primary female sexual characteristicsGO:004654540.013
signal transduction in absence of ligandGO:003803410.013
response to oxygen containing compoundGO:1901700550.013
meiosis iGO:000712710.013
blood vessel developmentGO:00015682460.013
regulation of alternative mrna splicing via spliceosomeGO:000038110.013
regulation of blood pressureGO:000821710.013
regulation of protein polymerizationGO:003227120.013
er to golgi vesicle mediated transportGO:000688810.013
cell agingGO:000756920.013
establishment of localization in cellGO:0051649770.013
regulation of protein complex disassemblyGO:004324410.013
organic acid metabolic processGO:0006082310.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
regulation of intracellular protein transportGO:003315730.013
positive regulation of muscle organ developmentGO:004863610.012
circadian sleep wake cycle processGO:002241020.012
positive regulation of i kappab kinase nf kappab signalingGO:004312330.012
odontogenesis of dentin containing toothGO:004247510.012
mitotic dna integrity checkpointGO:004477440.012
stem cell maintenanceGO:001982740.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
nucleic acid metabolic processGO:00903042440.012
negative regulation of mapk cascadeGO:004340940.012
antimicrobial humoral responseGO:001973020.012
hormone biosynthetic processGO:004244630.012
regulation of multicellular organismal developmentGO:20000262230.012
rna transportGO:005065820.012
gland developmentGO:00487321430.012
positive regulation of jnk cascadeGO:004633030.012
cell morphogenesis involved in differentiationGO:00009041950.012
positive regulation of leukocyte mediated immunityGO:000270510.012
neurotransmitter secretionGO:000726920.012
cell cycle g1 s phase transitionGO:004484310.012
regulation of metal ion transportGO:001095940.012
gastrulation with mouth forming secondGO:0001702440.012
adherens junction organizationGO:003433240.012
dorsal ventral pattern formationGO:00099531250.012
regulation of blood vessel sizeGO:005088020.012
ear developmentGO:00435831270.012
stem cell divisionGO:001714510.012
response to nutrientGO:000758430.012
positive regulation of cell activationGO:005086710.012
heterocycle biosynthetic processGO:00181302150.012
skeletal muscle tissue developmentGO:0007519670.012
lamellipodium organizationGO:009758110.012
digestive tract morphogenesisGO:00485462310.012
regulation of protein bindingGO:004339330.012
regulation of translational initiationGO:000644610.012
negative regulation of nucleocytoplasmic transportGO:004682320.012
regulation of mrna splicing via spliceosomeGO:004802430.012
peptidyl serine modificationGO:001820920.012
positive regulation of cytoskeleton organizationGO:005149530.012
dna templated transcription elongationGO:000635430.012
regulation of response to extracellular stimulusGO:003210410.012
lymphocyte proliferationGO:004665110.012
negative regulation of stem cell differentiationGO:200073720.012
neurotransmitter transportGO:000683620.012
negative regulation of cell communicationGO:0010648960.012
positive regulation of stem cell proliferationGO:200064810.011
cellular component assemblyGO:00226071700.011
centrosome organizationGO:005129710.011
regulation of protein transportGO:005122330.011
response to ketoneGO:190165410.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
regulation of cell deathGO:00109411030.011
single organism membrane fusionGO:004480120.011
regulation of organ growthGO:004662030.011
double strand break repair via homologous recombinationGO:000072410.011
positive regulation of cell adhesionGO:004578510.011
cell matrix adhesionGO:000716040.011
negative regulation of secretion by cellGO:190353120.011
macromolecule biosynthetic processGO:00090592270.011
primary neural tube formationGO:001402010.011
cellular respirationGO:004533330.011
protein homooligomerizationGO:005126030.011
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.011
heart morphogenesisGO:00030071560.011
insulin like growth factor receptor signaling pathwayGO:004800940.011
regulation of anatomical structure morphogenesisGO:00226031300.011
regulation of endocrine processGO:004406020.011
positive regulation of epithelial cell proliferationGO:005067910.011
cellular amino acid metabolic processGO:000652070.011
protein targeting to vacuoleGO:000662310.011
post golgi vesicle mediated transportGO:000689210.011
regulation of autophagyGO:001050630.011
regulation of intracellular signal transductionGO:1902531570.011
energy reserve metabolic processGO:000611220.011
response to glucocorticoidGO:005138410.011
response to endogenous stimulusGO:0009719830.011
establishment of rna localizationGO:005123630.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
olfactory bulb developmentGO:002177240.011
regulation of leukocyte mediated immunityGO:000270310.011
regulation of carbohydrate metabolic processGO:000610940.011
response to lipidGO:0033993600.011
dna templated transcription initiationGO:000635210.011
cellular response to stressGO:0033554620.011
response to other organismGO:0051707970.011
gtp metabolic processGO:004603940.011
single organism cellular localizationGO:1902580460.011
eye morphogenesisGO:00485921440.011
regulation of synapse assemblyGO:005196330.011
endocrine processGO:005088620.011
cell cycleGO:0007049930.011
proteolysisGO:0006508380.011
embryonic organ developmentGO:00485683810.011
myeloid cell differentiationGO:0030099860.010
response to alkaloidGO:004327920.010
intracellular mrna localizationGO:000829810.010
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.010
establishment of synaptic vesicle localizationGO:009748010.010
organelle fusionGO:004828430.010
striated muscle tissue developmentGO:00147061100.010
mononuclear cell proliferationGO:003294310.010
cellular response to radiationGO:007147840.010
activation of mapk activityGO:000018730.010
negative regulation of intracellular signal transductionGO:1902532220.010
positive regulation of chromatin modificationGO:190331010.010
negative regulation of synapse assemblyGO:005196420.010
nucleic acid transportGO:005065720.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.010
positive regulation of myeloid cell differentiationGO:004563920.010
positive regulation of cell killingGO:003134320.010
negative regulation of myeloid cell differentiationGO:004563810.010
nephron epithelium morphogenesisGO:007208810.010
positive regulation of protein kinase b signalingGO:005189710.010
positive regulation of chromosome organizationGO:200125210.010
symbiosis encompassing mutualism through parasitismGO:004440340.010
positive regulation of nucleotide catabolic processGO:003081310.010
regulation of lipid transportGO:003236840.010
outflow tract morphogenesisGO:000315110.010
regulation of receptor activityGO:001046920.010
positive regulation of response to stimulusGO:0048584800.010
membrane invaginationGO:001032410.010
negative regulation of intracellular transportGO:003238730.010
muscle cell migrationGO:001481240.010
pectoral fin developmentGO:0033339500.010
regulation of microtubule cytoskeleton organizationGO:007050730.010
ribosomal small subunit biogenesisGO:004227420.010
negative regulation of cytokine productionGO:000181810.010

hic1l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.064
disease of metabolismDOID:001466700.016
cancerDOID:16200.016
disease of cellular proliferationDOID:1456600.016
musculoskeletal system diseaseDOID:1700.015
organ system cancerDOID:005068600.015
inherited metabolic disorderDOID:65500.014
nervous system diseaseDOID:86300.013
muscular diseaseDOID:008000000.012