Danio rerio

35 known processes

rem2

RAS (RAD and GEM)-like GTP binding 2

(Aliases: wu:fb02c07,si:ch211-119o8.5)

rem2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryonic organ developmentGO:00485683810.106
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.093
signal transductionGO:00071654550.078
maintenance of locationGO:005123540.077
establishment of localizationGO:00512342440.076
response to stressGO:00069502630.071
regulation of response to stimulusGO:00485832690.070
neuron differentiationGO:00301823530.065
agingGO:000756820.059
cation transmembrane transportGO:0098655650.055
heart developmentGO:00075073130.054
organelle organizationGO:00069962270.053
transportGO:00068102200.051
ion transmembrane transportGO:0034220910.049
determination of bilateral symmetryGO:00098552040.048
specification of symmetryGO:00097992040.048
cognitionGO:005089010.048
membrane fusionGO:006102520.048
larval developmentGO:000216420.047
adult behaviorGO:003053420.047
response to external stimulusGO:00096052640.047
cell projection organizationGO:00300302840.047
organelle fusionGO:004828430.046
cell projection morphogenesisGO:00488582440.046
single organism organelle organizationGO:19025891990.045
determination of left right symmetryGO:00073681790.045
cellular component morphogenesisGO:00329893360.043
single organism metabolic processGO:00447102170.041
regulation of cell communicationGO:00106462320.041
sensory organ developmentGO:00074233930.040
regulation of cell shapeGO:000836010.039
negative regulation of sequestering of calcium ionGO:005128340.039
inorganic ion transmembrane transportGO:0098660570.038
embryonic organ morphogenesisGO:00485622740.037
inorganic cation transmembrane transportGO:0098662500.036
multicellular organism growthGO:003526440.036
regulation of synaptic plasticityGO:004816710.036
cytoskeleton organizationGO:0007010960.036
sensory perception of chemical stimulusGO:000760630.035
organelle assemblyGO:00709251100.035
cellular component assembly involved in morphogenesisGO:00109271070.035
morphogenesis of an epitheliumGO:00020093330.035
cell surface receptor signaling pathwayGO:00071663250.035
sequestering of metal ionGO:005123830.034
regulation of circadian rhythmGO:004275240.034
proteasomal protein catabolic processGO:001049820.034
central nervous system developmentGO:00074173870.034
cellular component movementGO:00069283350.034
cellular component assemblyGO:00226071700.034
muscle cell differentiationGO:00426921390.033
single organism membrane fusionGO:004480120.033
regulation of multicellular organism growthGO:004001440.033
system processGO:00030081850.033
cellular protein catabolic processGO:004425740.032
regulation of metabolic processGO:00192223590.031
head developmentGO:00603223030.031
regulation of sequestering of calcium ionGO:005128240.031
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.031
negative regulation of biological processGO:00485193040.031
cellular biosynthetic processGO:00442492860.030
nitrogen compound metabolic processGO:00068073190.030
cellular component biogenesisGO:00440851780.030
regulation of signal transductionGO:00099662250.030
regulation of rna biosynthetic processGO:20011412130.030
striated muscle cell differentiationGO:00511461290.030
cell morphogenesisGO:00009022890.030
cellular response to nutrient levelsGO:003166920.029
ear developmentGO:00435831270.029
guanosine containing compound catabolic processGO:190106920.029
lipid storageGO:001991510.028
muscle structure developmentGO:00610611960.028
autophagyGO:000691440.028
regulation of signalingGO:00230512350.028
tube morphogenesisGO:00352393490.028
transmembrane transportGO:00550851200.028
cilium assemblyGO:0042384580.028
gtp metabolic processGO:004603940.028
organic substance biosynthetic processGO:19015762890.028
behaviorGO:0007610740.027
locomotionGO:00400113130.026
lateral inhibitionGO:004633110.026
regulation of biological qualityGO:00650082630.026
guanosine containing compound metabolic processGO:190106840.026
proteolysis involved in cellular protein catabolic processGO:005160330.026
immune system developmentGO:00025201910.026
regulation of developmental processGO:00507932470.026
neuron developmentGO:00486662620.026
single organism transportGO:00447652060.025
single organism localizationGO:19025782250.025
negative regulation of cellular processGO:00485232830.025
neurological system processGO:0050877620.025
establishment of organelle localizationGO:0051656450.025
digestive system developmentGO:00551232890.025
regulation of cellular metabolic processGO:00313233200.025
sequestering of calcium ionGO:005120830.025
digestive tract developmentGO:00485652650.024
regulation of nucleotide catabolic processGO:003081120.024
cell part morphogenesisGO:00329902460.024
response to chemicalGO:00422213200.024
positive regulation of biological processGO:00485182530.023
modification dependent macromolecule catabolic processGO:004363230.023
embryonic skeletal system morphogenesisGO:0048704930.023
cellular response to external stimulusGO:007149620.023
regulation of reproductive processGO:200024140.023
receptor recyclingGO:000188140.023
programmed cell deathGO:00125011190.022
cell projection assemblyGO:0030031640.022
regulation of dendrite morphogenesisGO:004881430.021
cell migrationGO:00164772370.021
microtubule based movementGO:0007018330.021
regulation of macromolecule metabolic processGO:00602553170.021
inner ear developmentGO:00488391260.021
regulation of membrane potentialGO:0042391230.021
brain developmentGO:00074202930.021
meiotic nuclear divisionGO:000712640.021
small molecule metabolic processGO:0044281770.021
negative regulation of protein phosphorylationGO:000193340.020
vasculature developmentGO:00019442780.020
embryonic skeletal system developmentGO:0048706970.020
gtp catabolic processGO:000618420.020
negative regulation of signal transductionGO:0009968940.020
regulation of purine nucleotide catabolic processGO:003312120.020
protein metabolic processGO:00195381830.020
nucleobase containing compound metabolic processGO:00061392740.020
digestive tract morphogenesisGO:00485462310.020
actin filament based movementGO:003004810.019
cellular response to starvationGO:000926710.019
sensory organ morphogenesisGO:00905962000.019
nucleobase containing compound biosynthetic processGO:00346542050.019
negative regulation of reproductive processGO:200024230.019
muscle cell developmentGO:00550011150.019
neuron projection developmentGO:00311751800.019
cellular response to extracellular stimulusGO:003166820.019
regulation of blood pressureGO:000821710.019
cilium organizationGO:0044782710.019
purine nucleoside monophosphate catabolic processGO:000912840.019
ubiquitin dependent protein catabolic processGO:000651130.018
oxoacid metabolic processGO:0043436310.018
sensory perceptionGO:0007600390.018
synaptic vesicle localizationGO:009747910.018
gastrulationGO:00073692080.018
blood circulationGO:0008015870.018
phototransductionGO:000760220.018
modification dependent protein catabolic processGO:001994130.018
cation transportGO:0006812810.018
axon developmentGO:00615641660.018
actin filament based processGO:0030029640.018
exocytosisGO:000688710.018
heart loopingGO:0001947940.018
regulation of organelle assemblyGO:190211540.018
response to organic substanceGO:00100331530.018
i kappab kinase nf kappab signalingGO:000724940.018
positive regulation of cell cycleGO:004578730.017
negative regulation of protein kinase activityGO:000646940.017
positive regulation of cytosolic calcium ion concentrationGO:000720440.017
regulation of primary metabolic processGO:00800903110.017
heterocycle biosynthetic processGO:00181302150.017
regulation of multicellular organismal processGO:00512392770.017
cellular localizationGO:0051641970.017
positive regulation of cellular catabolic processGO:003133130.017
growthGO:00400071740.017
actin filament polymerizationGO:003004120.017
regulation of nervous system developmentGO:0051960900.017
cellular response to radiationGO:007147840.017
chordate embryonic developmentGO:00430092710.016
cellular response to light stimulusGO:007148240.016
phagocytosisGO:000690930.016
cellular macromolecule metabolic processGO:00442603910.016
heterocycle metabolic processGO:00464832900.016
cellular nitrogen compound metabolic processGO:00346412900.016
positive regulation of transportGO:005105020.016
regulation of dendrite developmentGO:005077330.016
antimicrobial humoral responseGO:001973020.016
intracellular signal transductionGO:0035556850.016
immune system processGO:00023762410.016
organism emergence from protective structureGO:007168440.016
regulation of cytoplasmic transportGO:190364940.016
striated muscle cell developmentGO:00550021080.016
gene expressionGO:00104672520.016
action potentialGO:0001508190.016
embryonic heart tube morphogenesisGO:00031431080.016
embryonic cranial skeleton morphogenesisGO:0048701900.016
regulation of neuronal synaptic plasticityGO:004816810.016
regulation of synapse assemblyGO:005196330.016
locomotory behaviorGO:0007626340.016
transcription dna templatedGO:00063511810.015
apoptotic processGO:00069151160.015
centrosome organizationGO:005129710.015
appendage developmentGO:0048736800.015
heart morphogenesisGO:00030071560.015
embryo development ending in birth or egg hatchingGO:00097922710.015
establishment of synaptic vesicle localizationGO:009748010.015
regulation of muscle contractionGO:000693730.015
retina development in camera type eyeGO:00600411460.015
multi organism processGO:00517041340.015
aromatic compound biosynthetic processGO:00194382170.015
organelle localizationGO:0051640490.015
regulation of multicellular organismal developmentGO:20000262230.015
ribonucleoside monophosphate catabolic processGO:000915840.015
regulation of protein transportGO:005122330.015
meiotic cell cycle processGO:190304630.015
phototransduction visible lightGO:000760320.015
positive regulation of catabolic processGO:000989640.015
actin cytoskeleton organizationGO:0030036630.015
regulation of protein modification by small protein conjugation or removalGO:190332030.015
regulation of cellular component organizationGO:0051128860.015
g protein coupled receptor signaling pathwayGO:0007186740.015
rna biosynthetic processGO:00327741810.015
carboxylic acid metabolic processGO:0019752220.015
nucleic acid metabolic processGO:00903042440.015
peptide metabolic processGO:000651810.014
protein polymerizationGO:005125840.014
ion transportGO:00068111140.014
neurotransmitter transportGO:000683620.014
regulation of gtp catabolic processGO:003312420.014
mitochondrion organizationGO:000700540.014
cellular component disassemblyGO:002241110.014
regulation of gtpase activityGO:004308720.014
establishment of protein localization to organelleGO:007259440.014
nucleoside monophosphate catabolic processGO:000912540.014
protein homooligomerizationGO:005126030.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
eye developmentGO:00016542770.014
microtubule organizing center organizationGO:003102310.014
endosomal transportGO:001619720.014
positive regulation of purine nucleotide catabolic processGO:003312310.014
organonitrogen compound metabolic processGO:1901564740.014
regulation of establishment of protein localizationGO:007020140.014
liver developmentGO:0001889960.014
golgi organizationGO:000703010.014
actin mediated cell contractionGO:007025210.014
embryonic viscerocranium morphogenesisGO:0048703520.014
regulation of i kappab kinase nf kappab signalingGO:004312240.014
rna localizationGO:000640340.014
positive regulation of stress activated mapk cascadeGO:003287430.014
cellular response to stressGO:0033554620.014
positive regulation of protein complex assemblyGO:003133420.014
regulation of cellular biosynthetic processGO:00313262450.013
adherens junction organizationGO:003433240.013
cellular modified amino acid metabolic processGO:000657530.013
cellular amine metabolic processGO:004410620.013
generation of neuronsGO:00486993850.013
calcium ion transmembrane transportGO:0070588130.013
regulation of nitrogen compound metabolic processGO:00511712510.013
phosphorus metabolic processGO:00067931090.013
convergent extensionGO:00600261180.013
cell morphogenesis involved in differentiationGO:00009041950.013
gland developmentGO:00487321430.013
protein localization to nucleusGO:003450430.013
regulation of tube sizeGO:003515020.013
locomotor rhythmGO:004547530.013
regulation of organ growthGO:004662030.013
alcohol biosynthetic processGO:004616520.013
response to topologically incorrect proteinGO:003596620.013
cellular response to chemical stimulusGO:00708871570.013
stem cell maintenanceGO:001982740.013
hemopoiesisGO:00300971830.013
nucleic acid templated transcriptionGO:00976591810.013
skeletal system morphogenesisGO:00487051020.013
positive regulation of cellular processGO:00485222010.013
cell motilityGO:00488702440.013
regulation of synapse organizationGO:005080730.013
regulation of biosynthetic processGO:00098892500.013
cellular amide metabolic processGO:004360340.013
cellular protein metabolic processGO:00442671290.013
regulation of macromolecule biosynthetic processGO:00105562250.013
eye morphogenesisGO:00485921440.012
regulation of rna metabolic processGO:00512522240.012
positive regulation of i kappab kinase nf kappab signalingGO:004312330.012
protein complex disassemblyGO:004324110.012
detection of stimulusGO:0051606290.012
cell cycleGO:0007049930.012
regulation of epithelial cell proliferationGO:005067830.012
positive regulation of jnk cascadeGO:004633030.012
regulation of nucleocytoplasmic transportGO:004682220.012
organic acid metabolic processGO:0006082310.012
negative regulation of intracellular protein transportGO:009031730.012
regulation of nucleic acid templated transcriptionGO:19035062130.012
peptide transportGO:001583310.012
fin developmentGO:0033333770.012
phosphate containing compound metabolic processGO:00067961080.012
actin polymerization or depolymerizationGO:000815420.012
cellular aromatic compound metabolic processGO:00067252950.012
developmental growthGO:00485891660.012
regulation of cytokine productionGO:000181730.012
neurotransmitter secretionGO:000726920.012
positive regulation of translationGO:004572710.012
regulation of bindingGO:005109830.012
skeletal system developmentGO:00015011810.012
macromolecule biosynthetic processGO:00090592270.012
synaptic vesicle transportGO:004848910.012
macroautophagyGO:001623610.012
regulation of cell activationGO:005086510.012
multicellular organismal signalingGO:0035637220.012
negative regulation of epithelial cell proliferationGO:005068010.012
blood vessel morphogenesisGO:00485142160.012
organic cyclic compound metabolic processGO:19013603010.012
hatchingGO:003518840.012
developmental programmed cell deathGO:001062340.012
regulation of nucleoside metabolic processGO:000911820.012
dicarboxylic acid metabolic processGO:004364810.012
regionalizationGO:00030022740.012
cellular nitrogen compound biosynthetic processGO:00442712180.012
regulation of apoptotic processGO:0042981980.012
nuclear transportGO:005116940.012
purine ribonucleoside monophosphate catabolic processGO:000916940.012
vacuolar transportGO:000703420.012
response to monosaccharideGO:003428430.011
regulation of gene expressionGO:00104682650.011
negative regulation of response to stimulusGO:00485851040.011
determination of heart left right asymmetryGO:00613711170.011
positive regulation of nucleoside metabolic processGO:004597910.011
adherens junction assemblyGO:003433310.011
regulation of heart growthGO:006042020.011
camera type eye developmentGO:00430102220.011
circulatory system processGO:0003013870.011
regulation of protein ubiquitinationGO:003139630.011
triglyceride homeostasisGO:007032820.011
rna metabolic processGO:00160702190.011
positive regulation of cell divisionGO:005178120.011
regulation of protein complex assemblyGO:004325430.011
regulation of localizationGO:00328791040.011
hepaticobiliary system developmentGO:0061008980.011
localization of cellGO:00516742440.011
negative regulation of ras protein signal transductionGO:004658010.011
amine metabolic processGO:000930820.011
biosynthetic processGO:00090582940.011
negative regulation of protein import into nucleusGO:004230820.011
protein stabilizationGO:005082120.011
regulation of response to oxidative stressGO:190288220.011
embryonic heart tube developmentGO:00350501330.011
mesenchyme developmentGO:00604851270.011
tissue remodelingGO:004877140.011
macromolecule modificationGO:00434121110.011
positive regulation of secretion by cellGO:190353210.011
synaptic growth at neuromuscular junctionGO:005112420.011
organic cyclic compound biosynthetic processGO:19013622230.011
regulation of metal ion transportGO:001095940.011
response to uvGO:000941130.011
protein localization to plasma membraneGO:007265910.011
striated muscle tissue developmentGO:00147061100.011
negative regulation of apoptotic processGO:0043066550.011
protein complex subunit organizationGO:0071822460.011
secondary metabolic processGO:001974830.011
negative regulation of kinase activityGO:003367340.011
establishment of localization in cellGO:0051649770.011
single organism biosynthetic processGO:0044711710.011
negative regulation of cell communicationGO:0010648960.011
cellular amino acid metabolic processGO:000652070.011
regulation of striated muscle contractionGO:000694220.011
neuronal action potentialGO:0019228180.011
regulation of cellular amine metabolic processGO:003323800.010
neuromast developmentGO:0048884460.010
deathGO:00162651210.010
detection of external stimulusGO:0009581240.010
positive regulation of nucleotide catabolic processGO:003081310.010
regulation of catalytic activityGO:0050790550.010
cell deathGO:00082191210.010
lipid homeostasisGO:005508830.010
protein modification processGO:00362111000.010
protein targeting to nucleusGO:004474430.010
membrane repolarizationGO:008600920.010
negative regulation of multi organism processGO:004390130.010
cellular protein modification processGO:00064641000.010
regulation of blood vessel sizeGO:005088020.010
positive regulation of metabolic processGO:00098931080.010
convergent extension involved in gastrulationGO:0060027710.010
atp catabolic processGO:000620040.010
alpha amino acid metabolic processGO:190160530.010
macromolecular complex disassemblyGO:003298410.010
regulation of protein catabolic processGO:004217610.010
regulation of transcription dna templatedGO:00063552130.010
cellular macromolecule biosynthetic processGO:00346452240.010
regulation of synaptic growth at neuromuscular junctionGO:000858210.010
membrane invaginationGO:001032410.010
homeostatic processGO:00425921420.010

rem2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
muscular diseaseDOID:008000000.016
muscle tissue diseaseDOID:6600.016
myopathyDOID:42300.016
musculoskeletal system diseaseDOID:1700.016
cardiovascular system diseaseDOID:128700.015
cardiomyopathyDOID:005070000.015
heart diseaseDOID:11400.015
intrinsic cardiomyopathyDOID:006003600.015
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.015
disease of metabolismDOID:001466700.014
inherited metabolic disorderDOID:65500.014
nervous system diseaseDOID:86300.013