Danio rerio

0 known processes

klhl8

kelch-like 8 (Drosophila)

(Aliases: zgc:158266)

klhl8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
maintenance of locationGO:005123540.049
larval developmentGO:000216420.048
agingGO:000756820.040
response to chemicalGO:00422213200.034
adult behaviorGO:003053420.034
signal transductionGO:00071654550.032
positive regulation of transportGO:005105020.032
sensory organ developmentGO:00074233930.030
multicellular organism growthGO:003526440.030
lipid storageGO:001991510.030
regulation of multicellular organism growthGO:004001440.029
eye developmentGO:00016542770.029
tube morphogenesisGO:00352393490.029
positive regulation of cell cycleGO:004578730.029
regulation of cellular amine metabolic processGO:003323800.028
regulation of biological qualityGO:00650082630.027
amine metabolic processGO:000930820.027
stem cell maintenanceGO:001982740.027
cellular amine metabolic processGO:004410620.026
nitrogen compound metabolic processGO:00068073190.026
positive regulation of catabolic processGO:000989640.026
cellular nitrogen compound metabolic processGO:00346412900.026
regulation of synaptic plasticityGO:004816710.025
cell surface receptor signaling pathwayGO:00071663250.025
positive regulation of cellular catabolic processGO:003133130.025
heterocycle metabolic processGO:00464832900.024
neuron differentiationGO:00301823530.024
regulation of reproductive processGO:200024140.024
cellular response to external stimulusGO:007149620.024
cellular biosynthetic processGO:00442492860.023
system processGO:00030081850.023
meiotic cell cycle processGO:190304630.023
gtp catabolic processGO:000618420.023
guanosine containing compound metabolic processGO:190106840.023
cellular macromolecule metabolic processGO:00442603910.023
Human
guanosine containing compound catabolic processGO:190106920.023
phagocytosisGO:000690930.022
embryonic organ morphogenesisGO:00485622740.022
autophagyGO:000691440.022
regionalizationGO:00030022740.022
negative regulation of biological processGO:00485193040.022
regulation of nitrogen compound metabolic processGO:00511712510.022
regulation of cellular metabolic processGO:00313233200.021
regulation of gene expressionGO:00104682650.021
establishment of protein localization to organelleGO:007259440.021
carboxylic acid metabolic processGO:0019752220.021
gene expressionGO:00104672520.021
nucleobase containing compound metabolic processGO:00061392740.021
regulation of cellular amino acid metabolic processGO:000652100.021
negative regulation of protein phosphorylationGO:000193340.021
organic cyclic compound metabolic processGO:19013603010.021
synaptic growth at neuromuscular junctionGO:005112420.021
regulation of metabolic processGO:00192223590.021
sensory perception of chemical stimulusGO:000760630.021
cytokinesisGO:000091030.020
morphogenesis of an epitheliumGO:00020093330.020
response to drugGO:004249330.020
cellular response to extracellular stimulusGO:003166820.020
camera type eye developmentGO:00430102220.020
protein localization to nucleusGO:003450430.020
heterocycle biosynthetic processGO:00181302150.020
response to hexoseGO:000974630.020
generation of neuronsGO:00486993850.020
cellular ketone metabolic processGO:0042180110.020
g protein coupled receptor signaling pathwayGO:0007186740.020
chemosensory behaviorGO:000763510.020
hormone secretionGO:004687920.020
stem cell proliferationGO:007208940.020
embryonic organ developmentGO:00485683810.020
response to monosaccharideGO:003428430.020
response to carbohydrateGO:000974330.020
gtp metabolic processGO:004603940.020
cellular aromatic compound metabolic processGO:00067252950.020
nucleocytoplasmic transportGO:000691340.020
compound eye developmentGO:004874920.020
hormone transportGO:000991420.020
proteolysis involved in cellular protein catabolic processGO:005160330.019
Human
heart developmentGO:00075073130.019
regulation of sequestering of calcium ionGO:005128240.019
golgi vesicle transportGO:004819330.019
cognitionGO:005089010.019
cellular component movementGO:00069283350.019
regulation of cellular ketone metabolic processGO:001056570.019
modification dependent macromolecule catabolic processGO:004363230.019
Human
small molecule metabolic processGO:0044281770.019
rna metabolic processGO:00160702190.019
cellular component morphogenesisGO:00329893360.019
regulation of signalingGO:00230512350.019
response to stressGO:00069502630.019
chordate embryonic developmentGO:00430092710.019
biosynthetic processGO:00090582940.019
organic substance biosynthetic processGO:19015762890.019
regulation of protein catabolic processGO:004217610.019
rna biosynthetic processGO:00327741810.019
organic acid metabolic processGO:0006082310.019
mitochondrion organizationGO:000700540.018
digestive system developmentGO:00551232890.018
regulation of macromolecule metabolic processGO:00602553170.018
cellular nitrogen compound biosynthetic processGO:00442712180.018
regulation of blood pressureGO:000821710.018
sequestering of calcium ionGO:005120830.018
transportGO:00068102200.018
single organism metabolic processGO:00447102170.018
specification of symmetryGO:00097992040.018
single organism transportGO:00447652060.018
digestive tract morphogenesisGO:00485462310.018
regulation of primary metabolic processGO:00800903110.018
cellular response to nutrient levelsGO:003166920.018
regulation of protein complex assemblyGO:004325430.018
cellular protein catabolic processGO:004425740.018
Human
neurotransmitter transportGO:000683620.018
regulation of metal ion transportGO:001095940.018
nucleic acid metabolic processGO:00903042440.018
establishment of localizationGO:00512342440.018
aromatic compound biosynthetic processGO:00194382170.018
protein targeting to nucleusGO:004474430.018
sequestering of metal ionGO:005123830.018
regulation of synapse assemblyGO:005196330.017
regulation of establishment of protein localizationGO:007020140.017
response to glucoseGO:000974930.017
nuclear importGO:005117030.017
homeostatic processGO:00425921420.017
regulation of endocrine processGO:004406020.017
endocrine processGO:005088620.017
nuclear transportGO:005116940.017
peptide transportGO:001583310.017
regulation of cytoplasmic transportGO:190364940.017
regulation of purine nucleotide catabolic processGO:003312120.017
negative regulation of sequestering of calcium ionGO:005128340.017
modification dependent protein catabolic processGO:001994130.017
Human
heart loopingGO:0001947940.017
single organism localizationGO:19025782250.016
neuron neuron synaptic transmissionGO:000727010.016
macromolecule biosynthetic processGO:00090592270.016
determination of left right symmetryGO:00073681790.016
organic cyclic compound biosynthetic processGO:19013622230.016
regulation of tube sizeGO:003515020.016
response to organic substanceGO:00100331530.016
oxoacid metabolic processGO:0043436310.016
regulation of nucleoside metabolic processGO:000911820.016
cellular component disassemblyGO:002241110.016
cellular amino acid metabolic processGO:000652070.016
organonitrogen compound metabolic processGO:1901564740.016
cellular response to starvationGO:000926710.016
regulation of synaptic growth at neuromuscular junctionGO:000858210.016
regulation of dendrite developmentGO:005077330.016
negative regulation of cellular processGO:00485232830.016
ion transmembrane transportGO:0034220910.016
meiotic nuclear divisionGO:000712640.016
regulation of bindingGO:005109830.016
neurotransmitter secretionGO:000726920.016
nucleobase containing compound biosynthetic processGO:00346542050.016
female sex differentiationGO:004666040.016
regulation of cell activationGO:005086510.016
digestive tract developmentGO:00485652650.016
rna localizationGO:000640340.016
gastrulationGO:00073692080.016
response to corticosteroidGO:003196010.016
regulation of synapse organizationGO:005080730.016
ribonucleoside monophosphate catabolic processGO:000915840.016
epithelial tube morphogenesisGO:00605621480.015
regulation of neural precursor cell proliferationGO:200017730.015
negative regulation of catabolic processGO:000989530.015
head developmentGO:00603223030.015
locomotionGO:00400113130.015
regulation of cellular biosynthetic processGO:00313262450.015
nucleic acid templated transcriptionGO:00976591810.015
smooth muscle contractionGO:000693920.015
regulation of cytokine productionGO:000181730.015
organelle fusionGO:004828430.015
development of primary female sexual characteristicsGO:004654540.015
central nervous system developmentGO:00074173870.015
regulation of protein transportGO:005122330.015
negative regulation of protein kinase activityGO:000646940.015
response to external stimulusGO:00096052640.015
synaptic vesicle localizationGO:009747910.015
female gonad developmentGO:000858540.015
amino acid transportGO:000686520.015
regulation of developmental processGO:00507932470.015
carbohydrate homeostasisGO:003350010.015
regulation of biosynthetic processGO:00098892500.015
single organism nuclear importGO:190259330.015
cellular response to radiationGO:007147840.015
regulation of sodium ion transportGO:000202820.015
determination of bilateral symmetryGO:00098552040.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
glucose homeostasisGO:004259310.015
regulation of multicellular organismal developmentGO:20000262230.015
lipid catabolic processGO:001604240.015
cellular carbohydrate metabolic processGO:004426240.015
cellular response to molecule of bacterial originGO:007121930.015
regulation of blood vessel sizeGO:005088020.015
brain developmentGO:00074202930.015
positive regulation of secretion by cellGO:190353210.014
membrane fusionGO:006102520.014
regulation of hormone secretionGO:004688320.014
protein import into nucleusGO:000660630.014
cell part morphogenesisGO:00329902460.014
positive regulation of nucleotide catabolic processGO:003081310.014
cell projection organizationGO:00300302840.014
regulation of macromolecule biosynthetic processGO:00105562250.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
proteasomal protein catabolic processGO:001049820.014
regulation of nucleotide catabolic processGO:003081120.014
protein importGO:001703830.014
response to amino acidGO:004320020.014
neuroblast proliferationGO:000740520.014
regulation of circadian rhythmGO:004275240.014
calcium ion transport into cytosolGO:006040230.014
negative regulation of kinase activityGO:003367340.014
cellular response to light stimulusGO:007148240.014
embryonic heart tube developmentGO:00350501330.014
transmembrane transportGO:00550851200.014
cellular response to chemical stimulusGO:00708871570.014
transcription from rna polymerase ii promoterGO:0006366800.014
ion transportGO:00068111140.014
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
endosomal transportGO:001619720.014
exocytosisGO:000688710.014
retina development in camera type eyeGO:00600411460.014
cell projection morphogenesisGO:00488582440.014
regulation of gtp catabolic processGO:003312420.014
lipid homeostasisGO:005508830.014
phagocytosis engulfmentGO:000691110.014
tissue remodelingGO:004877140.014
positive regulation of cellular component biogenesisGO:004408930.014
protein acetylationGO:000647320.014
atp catabolic processGO:000620040.013
regulation of inflammatory responseGO:005072720.013
protein localization to plasma membraneGO:007265910.013
positive regulation of nucleoside metabolic processGO:004597910.013
regulation of signal transductionGO:00099662250.013
extrinsic apoptotic signaling pathwayGO:009719130.013
anterior posterior pattern specificationGO:00099521520.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
positive regulation of cellular amine metabolic processGO:003324000.013
positive regulation of biological processGO:00485182530.013
response to nutrientGO:000758430.013
response to vitaminGO:003327330.013
regulation of protein ubiquitinationGO:003139630.013
positive regulation of gtpase activityGO:004354710.013
positive regulation of reproductive processGO:200024320.013
germ line stem cell maintenanceGO:003071820.013
positive regulation of gtp catabolic processGO:003312610.013
actin polymerization or depolymerizationGO:000815420.013
b cell activationGO:004211320.013
cellular response to lipopolysaccharideGO:007122230.013
cellular macromolecule biosynthetic processGO:00346452240.013
cellular response to biotic stimulusGO:007121630.013
regulation of gtpase activityGO:004308720.013
positive regulation of cell divisionGO:005178120.013
purine nucleoside monophosphate catabolic processGO:000912840.013
transcription dna templatedGO:00063511810.013
cytosolic calcium ion transportGO:006040130.013
cellular response to organic substanceGO:00713101050.013
protein complex disassemblyGO:004324110.013
cell morphogenesisGO:00009022890.013
stem cell divisionGO:001714510.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
meiotic chromosome segregationGO:004513230.013
cell morphogenesis involved in differentiationGO:00009041950.013
internal protein amino acid acetylationGO:000647520.012
establishment of synaptic vesicle localizationGO:009748010.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
regulation of cellular protein catabolic processGO:190336210.012
epithelial cell differentiationGO:00308551160.012
heart morphogenesisGO:00030071560.012
membrane invaginationGO:001032410.012
peptidyl lysine acetylationGO:001839420.012
protein polymerizationGO:005125840.012
regulation of mrna processingGO:005068430.012
positive regulation of secretionGO:005104710.012
internal peptidyl lysine acetylationGO:001839320.012
maternal determination of anterior posterior axis embryoGO:000835840.012
regulation of nucleic acid templated transcriptionGO:19035062130.012
macromolecular complex disassemblyGO:003298410.012
cytoskeleton dependent cytokinesisGO:006164030.012
leukocyte mediated cytotoxicityGO:000190910.012
nucleoside monophosphate catabolic processGO:000912540.012
protein homooligomerizationGO:005126030.012
small molecule catabolic processGO:004428230.012
regulation of intracellular protein transportGO:003315730.012
segmentationGO:0035282970.012
alcohol biosynthetic processGO:004616520.012
somatic muscle developmentGO:000752540.012
carbohydrate biosynthetic processGO:001605110.012
regulation of cell communicationGO:00106462320.012
positive regulation of dna metabolic processGO:005105410.012
secondary metabolic processGO:001974830.012
macroautophagyGO:001623610.012
regulation of ion transmembrane transporter activityGO:003241220.012
positive regulation of cytoskeleton organizationGO:005149530.012
water homeostasisGO:003010440.012
response to uvGO:000941130.012
regulation of transmembrane transporter activityGO:002289820.012
intracellular mrna localizationGO:000829810.012
organelle organizationGO:00069962270.012
regulation of phGO:000688530.012
cell motilityGO:00488702440.012
muscle structure developmentGO:00610611960.012
somite developmentGO:0061053960.012
cell migrationGO:00164772370.012
monovalent inorganic cation transportGO:0015672420.012
regulation of meiotic cell cycleGO:005144510.012
negative regulation of chromosome organizationGO:200125110.012
single organism membrane fusionGO:004480120.012
positive regulation of blood circulationGO:190352420.012
hemopoiesisGO:00300971830.012
regulation of neuronal synaptic plasticityGO:004816810.012
regulation of systemic arterial blood pressureGO:000307310.012
embryonic heart tube morphogenesisGO:00031431080.012
cellular aldehyde metabolic processGO:000608140.012
cellular lipid catabolic processGO:004424230.012
positive regulation of nitrogen compound metabolic processGO:0051173690.011
ubiquitin dependent protein catabolic processGO:000651130.011
Human
regulation of cellular macromolecule biosynthetic processGO:20001122220.011
catechol containing compound metabolic processGO:000971220.011
eye morphogenesisGO:00485921440.011
regulation of dendrite morphogenesisGO:004881430.011
endocrine hormone secretionGO:006098620.011
skeletal system developmentGO:00015011810.011
regulation of transporter activityGO:003240920.011
mesenchyme developmentGO:00604851270.011
response to alkaloidGO:004327920.011
spermatid developmentGO:000728620.011
regulation of autophagyGO:001050630.011
gland developmentGO:00487321430.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
protein acylationGO:004354330.011
synaptic vesicle transportGO:004848910.011
response to glucocorticoidGO:005138410.011
positive regulation of protein complex assemblyGO:003133420.011
developmental growthGO:00485891660.011
phototransductionGO:000760220.011
regulation of neurotransmitter transportGO:005158810.011
regulation of nucleocytoplasmic transportGO:004682220.011
regulation of wound healingGO:006104120.011
water transportGO:0006833150.011
growthGO:00400071740.011
regulation of multicellular organismal processGO:00512392770.011
negative regulation of synapse assemblyGO:005196420.011
negative regulation of secretionGO:005104820.011
actin filament polymerizationGO:003004120.011
interspecies interaction between organismsGO:004441940.011
i kappab kinase nf kappab signalingGO:000724940.011
regulation of epithelial cell proliferationGO:005067830.011
sensory organ morphogenesisGO:00905962000.011
glial cell migrationGO:000834730.011
positive regulation of myeloid cell differentiationGO:004563920.011
immune system developmentGO:00025201910.011
positive regulation of immune effector processGO:000269930.011
lateral inhibitionGO:004633110.011
sensory perception of painGO:001923310.011
cellular amide metabolic processGO:004360340.011
mechanosensory behaviorGO:000763820.011
organism emergence from protective structureGO:007168440.011
ovulation cycle processGO:002260220.011
cortical cytoskeleton organizationGO:003086510.011
regulation of cell differentiationGO:00455951420.011
blood circulationGO:0008015870.011
leukocyte proliferationGO:007066110.011
actin filament based movementGO:003004810.011
stem cell differentiationGO:00488631170.011
protein stabilizationGO:005082120.010
cell cycle g1 s phase transitionGO:004484310.010
neuron developmentGO:00486662620.010
circulatory system processGO:0003013870.010
positive regulation of cell killingGO:003134320.010
negative regulation of defense responseGO:003134820.010
regulation of anatomical structure morphogenesisGO:00226031300.010
positive regulation of apoptotic signaling pathwayGO:200123510.010
lens fiber cell morphogenesisGO:007030930.010
regulation of oocyte developmentGO:006028130.010
embryo development ending in birth or egg hatchingGO:00097922710.010
regulation of peptidyl tyrosine phosphorylationGO:005073010.010
single fertilizationGO:000733830.010
somitogenesisGO:0001756870.010
establishment of protein localization to plasma membraneGO:009000210.010
response to endogenous stimulusGO:0009719830.010
tube closureGO:006060610.010
cell killingGO:000190620.010
adherens junction organizationGO:003433240.010
regulation of lipid transportGO:003236840.010
rna 3 end processingGO:003112320.010
fat soluble vitamin metabolic processGO:000677540.010
muscle cell differentiationGO:00426921390.010
mononuclear cell proliferationGO:003294310.010
vacuolar transportGO:000703420.010
inositol lipid mediated signalingGO:004801720.010
negative regulation of secretion by cellGO:190353120.010
multicellular organismal response to stressGO:003355520.010
positive regulation of epithelial cell differentiationGO:003085820.010

klhl8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
nervous system diseaseDOID:86300.015
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
musculoskeletal system diseaseDOID:1700.014
disease of metabolismDOID:001466700.014
organ system cancerDOID:005068600.014
eye diseaseDOID:561400.010
eye and adnexa diseaseDOID:149200.010
sensory system diseaseDOID:005015500.010