Danio rerio

0 known processes

plg

plasminogen

(Aliases: wu:fb70e09)

plg biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
blood coagulationGO:0007596120.395
Human
cellular response to estrogen stimulusGO:0071391240.387
blood coagulation fibrin clot formationGO:007237830.358
cell matrix adhesionGO:000716040.272
cellular macromolecule metabolic processGO:00442603910.166
Rat
extrinsic apoptotic signaling pathwayGO:009719130.155
response to hormoneGO:0009725480.149
hemostasisGO:0007599130.137
Human
mycotoxin metabolic processGO:004338510.123
regulation of extrinsic apoptotic signaling pathwayGO:200123630.119
cell substrate adhesionGO:003158940.088
Human
regulation of response to stimulusGO:00485832690.083
Human
response to estrogenGO:0043627270.076
regulation of protein transportGO:005122330.076
protein activation cascadeGO:007237660.072
nephron tubule morphogenesisGO:007207810.068
response to chemicalGO:00422213200.067
protein secretionGO:000930610.067
response to steroid hormoneGO:0048545350.067
cell motilityGO:00488702440.066
Zebrafish Mouse
response to organic substanceGO:00100331530.063
regulation of peptidase activityGO:0052547230.062
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.060
wound healingGO:0042060900.059
Human Mouse
agingGO:000756820.059
positive regulation of erk1 and erk2 cascadeGO:007037420.057
regulation of cytokine productionGO:000181730.056
digestive system developmentGO:00551232890.055
regulation of peptidyl tyrosine phosphorylationGO:005073010.054
larval developmentGO:000216420.053
carboxylic acid metabolic processGO:0019752220.051
protein metabolic processGO:00195381830.050
Human Rat
response to lipidGO:0033993600.048
negative regulation of protein processingGO:0010955100.048
negative regulation of cellular processGO:00485232830.047
Human
immune system processGO:00023762410.045
Mouse
regulation of hemostasisGO:190004610.045
Human
cellular response to chemical stimulusGO:00708871570.045
positive regulation of apoptotic signaling pathwayGO:200123510.045
cellular amino acid metabolic processGO:000652070.042
cellular response to lipidGO:0071396390.042
cellular component movementGO:00069283350.042
Zebrafish Mouse
regulation of establishment of protein localizationGO:007020140.041
small molecule metabolic processGO:0044281770.041
blood circulationGO:0008015870.041
regulation of inflammatory responseGO:005072720.040
positive regulation of cellular amine metabolic processGO:003324000.040
signal transductionGO:00071654550.040
cell surface receptor signaling pathwayGO:00071663250.039
regulation of blood vessel sizeGO:005088020.038
system processGO:00030081850.037
positive regulation of cellular amino acid metabolic processGO:004576400.037
positive regulation of transportGO:005105020.037
protein modification processGO:00362111000.036
regulation of cellular metabolic processGO:00313233200.036
cell adhesionGO:0007155400.036
Human
female sex differentiationGO:004666040.036
positive regulation of secretion by cellGO:190353210.035
phosphorus metabolic processGO:00067931090.034
cellular response to hormone stimulusGO:0032870390.034
cellular amine metabolic processGO:004410620.034
regulation of cellular amino acid metabolic processGO:000652100.034
circulatory system processGO:0003013870.033
regulation of signal transductionGO:00099662250.033
regulation of cellular amine metabolic processGO:003323800.032
oxoacid metabolic processGO:0043436310.032
positive regulation of cytosolic calcium ion concentrationGO:000720440.032
regulation of defense responseGO:0031347140.031
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.031
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.031
peptidyl serine phosphorylationGO:001810510.031
regulation of cell substrate adhesionGO:001081010.030
Human
negative regulation of endopeptidase activityGO:0010951100.030
regulation of protein metabolic processGO:0051246560.030
programmed cell deathGO:00125011190.030
response to organic cyclic compoundGO:0014070510.030
regulation of cell adhesionGO:0030155150.030
Human
protein polymerizationGO:005125840.030
fertilizationGO:000956630.030
development of primary female sexual characteristicsGO:004654540.029
morphogenesis of an epitheliumGO:00020093330.029
regulation of multicellular organismal developmentGO:20000262230.029
positive regulation of cell adhesionGO:004578510.029
response to woundingGO:00096111160.029
Human Mouse
positive regulation of blood circulationGO:190352420.028
cellular response to endogenous stimulusGO:0071495680.028
regulation of multicellular organismal processGO:00512392770.028
Human
fatty acid biosynthetic processGO:000663340.028
digestive tract developmentGO:00485652650.027
meiotic nuclear divisionGO:000712640.027
organic acid metabolic processGO:0006082310.027
stem cell divisionGO:001714510.027
developmental growthGO:00485891660.027
Mouse
positive regulation of exocytosisGO:004592110.027
tissue regenerationGO:0042246740.027
Mouse
spermatid differentiationGO:004851520.027
apoptotic process involved in developmentGO:190274220.026
cellular component biogenesisGO:00440851780.026
multi organism processGO:00517041340.026
cellular response to external stimulusGO:007149620.026
single organism organelle organizationGO:19025891990.026
lipoprotein catabolic processGO:004215910.025
positive regulation of cytokine productionGO:000181920.025
negative regulation of defense responseGO:003134820.025
cellular response to organic cyclic compoundGO:0071407380.025
regulation of blood coagulationGO:003019310.025
Human
regulation of organ growthGO:004662030.025
regulation of protein processingGO:0070613100.025
protein processingGO:0016485120.024
cellular ketone metabolic processGO:0042180110.024
response to biotic stimulusGO:0009607970.024
amine metabolic processGO:000930820.024
monocarboxylic acid catabolic processGO:007232930.024
meiotic chromosome segregationGO:004513230.023
astrocyte differentiationGO:004870810.023
response to glucoseGO:000974930.023
nuclear divisionGO:0000280230.023
response to endogenous stimulusGO:0009719830.023
positive regulation of secretionGO:005104710.023
response to external stimulusGO:00096052640.023
Human
regulation of immune system processGO:0002682340.023
regulation of multicellular organism growthGO:004001440.022
vasculature developmentGO:00019442780.022
Mouse
epithelial tube morphogenesisGO:00605621480.022
cellular component assemblyGO:00226071700.022
cellular response to organic substanceGO:00713101050.022
regulation of biological qualityGO:00650082630.022
Human Mouse
renal tubule morphogenesisGO:006133310.022
single organism localizationGO:19025782250.022
organic cyclic compound metabolic processGO:19013603010.021
single organism metabolic processGO:00447102170.021
regulation of cellular ketone metabolic processGO:001056570.021
phasic smooth muscle contractionGO:001482110.021
cellular response to nutrient levelsGO:003166920.020
cellular protein metabolic processGO:00442671290.020
Rat
deathGO:00162651210.020
regulation of wound healingGO:006104120.020
Human
regulation of endopeptidase activityGO:0052548230.020
regulation of macromolecule metabolic processGO:00602553170.020
heterocycle metabolic processGO:00464832900.019
regulation of cell migrationGO:0030334400.019
central nervous system developmentGO:00074173870.019
Zebrafish
nik nf kappab signalingGO:003806110.019
erk1 and erk2 cascadeGO:007037140.019
response to stressGO:00069502630.019
Human Mouse
lipid catabolic processGO:001604240.019
nephron epithelium morphogenesisGO:007208810.019
cellular response to extracellular stimulusGO:003166820.018
regulation of programmed cell deathGO:00430671010.018
negative regulation of protein maturationGO:1903318100.018
blood vessel developmentGO:00015682460.017
Mouse
regulation of tube sizeGO:003515020.017
heart morphogenesisGO:00030071560.017
meiotic cell cycle processGO:190304630.017
female gonad developmentGO:000858540.017
rna metabolic processGO:00160702190.017
cell morphogenesisGO:00009022890.017
cellular lipid catabolic processGO:004424230.017
response to other organismGO:0051707970.017
phagocytosisGO:000690930.016
response to coldGO:000940940.016
biological adhesionGO:0022610400.016
Human
regulation of proteolysisGO:0030162240.016
response to bacteriumGO:0009617580.016
regulation of hormone secretionGO:004688320.016
nephron morphogenesisGO:007202820.016
cellular macromolecular complex assemblyGO:0034622240.016
transportGO:00068102200.016
positive regulation of response to stimulusGO:0048584800.016
Human
regulation of fatty acid metabolic processGO:001921710.016
locomotionGO:00400113130.015
Zebrafish Mouse
gland developmentGO:00487321430.015
positive regulation of biological processGO:00485182530.015
Human
lens fiber cell developmentGO:007030730.015
regulation of cell shapeGO:000836010.015
phosphatidylinositol 3 kinase signalingGO:001406520.015
b cell mediated immunityGO:001972430.015
regulation of metabolic processGO:00192223590.015
muscle cell differentiationGO:00426921390.015
Mouse
positive regulation of immune system processGO:0002684170.015
inositol lipid mediated signalingGO:004801720.015
cell migrationGO:00164772370.015
Zebrafish Mouse
growthGO:00400071740.015
Mouse
negative regulation of peptidase activityGO:0010466100.014
positive regulation of striated muscle tissue developmentGO:004584410.014
intracellular signal transductionGO:0035556850.014
response to nutrientGO:000758430.014
regulation of cell activationGO:005086510.014
regulation of protein maturationGO:1903317100.014
multicellular organism growthGO:003526440.014
renal system developmentGO:0072001940.014
epithelial cell differentiationGO:00308551160.014
endothelial cell differentiationGO:0045446200.014
immune effector processGO:0002252230.014
phosphatidylinositol mediated signalingGO:004801520.014
response to external biotic stimulusGO:0043207970.013
transcription dna templatedGO:00063511810.013
negative regulation of response to stimulusGO:00485851040.013
Human
regulation of muscle hypertrophyGO:001474320.013
synaptic growth at neuromuscular junctionGO:005112420.013
hormone secretionGO:004687920.013
digestive tract morphogenesisGO:00485462310.013
localization of cellGO:00516742440.013
Zebrafish Mouse
cell deathGO:00082191210.013
regulation of protein catabolic processGO:004217610.013
organic acid biosynthetic processGO:0016053120.013
regulation of cell communicationGO:00106462320.013
maintenance of locationGO:005123540.013
i kappab kinase nf kappab signalingGO:000724940.013
organonitrogen compound metabolic processGO:1901564740.013
negative regulation of signal transductionGO:0009968940.013
negative regulation of cell communicationGO:0010648960.013
peristalsisGO:003043210.013
cellular response to starvationGO:000926710.013
positive regulation of response to external stimulusGO:003210390.013
g protein coupled receptor signaling pathwayGO:0007186740.013
smooth muscle contractionGO:000693920.013
regulation of systemic arterial blood pressureGO:000307310.013
endothelium developmentGO:0003158250.013
regulation of catalytic activityGO:0050790550.012
peripheral nervous system developmentGO:0007422550.012
macromolecule modificationGO:00434121110.012
muscle structure developmentGO:00610611960.012
Mouse
sexual reproductionGO:0019953360.012
regulation of body fluid levelsGO:0050878160.012
Human
response to carbohydrateGO:000974330.012
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.012
regulation of anatomical structure morphogenesisGO:00226031300.012
autophagyGO:000691440.012
gastrulationGO:00073692080.012
regulation of signalingGO:00230512350.012
gamete generationGO:0007276330.012
regulation of stem cell proliferationGO:007209120.012
organic cyclic compound biosynthetic processGO:19013622230.012
regulation of biosynthetic processGO:00098892500.012
cellular protein modification processGO:00064641000.012
response to abiotic stimulusGO:00096281220.012
apoptotic processGO:00069151160.012
cellular nitrogen compound metabolic processGO:00346412900.012
cerebellar granular layer morphogenesisGO:002168330.012
Zebrafish
regulation of response to stressGO:0080134360.012
Human
cellular response to molecule of bacterial originGO:007121930.012
antimicrobial humoral responseGO:001973020.012
neuroblast proliferationGO:000740520.012
ovulation cycle processGO:002260220.011
embryonic heart tube morphogenesisGO:00031431080.011
rhythmic processGO:0048511210.011
negative regulation of hydrolase activityGO:0051346100.011
g1 s transition of mitotic cell cycleGO:000008210.011
regulation of erk1 and erk2 cascadeGO:007037240.011
lipid storageGO:001991510.011
generation of neuronsGO:00486993850.011
Zebrafish
humoral immune response mediated by circulating immunoglobulinGO:000245530.011
hepaticobiliary system developmentGO:0061008980.011
negative regulation of proteolysisGO:0045861100.011
tube morphogenesisGO:00352393490.011
peptide transportGO:001583310.011
gene expressionGO:00104672520.011
glucocorticoid metabolic processGO:000821120.011
organic acid catabolic processGO:001605430.011
negative regulation of metabolic processGO:0009892860.011
response to monosaccharideGO:003428430.011
positive regulation of cellular processGO:00485222010.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
interspecies interaction between organismsGO:004441940.011
negative regulation of apoptotic processGO:0043066550.010
cellular lipid metabolic processGO:0044255360.010
phototransductionGO:000760220.010
extracellular structure organizationGO:0043062270.010
Human
muscle organ developmentGO:00075171010.010
blood vessel morphogenesisGO:00485142160.010
cell chemotaxisGO:0060326170.010
regulation of translational initiationGO:000644610.010
defense response to fungusGO:005083220.010
peptidyl serine modificationGO:001820920.010
cellular protein complex assemblyGO:0043623190.010
multicellular organismal reproductive processGO:0048609350.010
negative regulation of gene expressionGO:0010629650.010
positive regulation of jak stat cascadeGO:004642720.010
regulation of intracellular signal transductionGO:1902531570.010
defense responseGO:0006952470.010
neural crest cell developmentGO:0014032620.010
regulation of apoptotic processGO:0042981980.010
rna biosynthetic processGO:00327741810.010
proteolysis involved in cellular protein catabolic processGO:005160330.010
Rat
response to ketoneGO:190165410.010

plg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.083
amyloidosisDOID:912000.076
disease of metabolismDOID:001466700.076
acquired metabolic diseaseDOID:006015800.076
hematopoietic system diseaseDOID:7400.055
immune system diseaseDOID:291400.055
congenital hypoplastic anemiaDOID:134200.021
aplastic anemiaDOID:1244900.021
bone marrow diseaseDOID:496100.021
anemiaDOID:235500.021