Danio rerio

0 known processes

capn2a

calpain 2, (m/II) large subunit a

(Aliases: zgc:113590)

capn2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
digestive tract morphogenesisGO:00485462310.121
protein importGO:001703830.118
agingGO:000756820.101
larval developmentGO:000216420.095
positive regulation of cellular component biogenesisGO:004408930.094
central nervous system developmentGO:00074173870.080
protein localization to nucleusGO:003450430.072
regulation of cell shapeGO:000836010.071
cell part morphogenesisGO:00329902460.070
anterior posterior pattern specificationGO:00099521520.066
protein import into nucleusGO:000660630.066
digestive system developmentGO:00551232890.063
generation of neuronsGO:00486993850.062
cellular component movementGO:00069283350.062
reflexGO:006000420.061
gland developmentGO:00487321430.057
embryo development ending in birth or egg hatchingGO:00097922710.056
axonogenesisGO:00074091520.055
positive regulation of catabolic processGO:000989640.054
response to external stimulusGO:00096052640.052
cell morphogenesis involved in differentiationGO:00009041950.052
response to chemicalGO:00422213200.051
regulation of synapse organizationGO:005080730.051
stem cell maintenanceGO:001982740.050
head developmentGO:00603223030.050
brain developmentGO:00074202930.050
cellular response to lipopolysaccharideGO:007122230.049
nucleocytoplasmic transportGO:000691340.049
digestive tract developmentGO:00485652650.048
regulation of synapse assemblyGO:005196330.048
cognitionGO:005089010.048
response to organic substanceGO:00100331530.047
cell projection organizationGO:00300302840.047
nuclear transportGO:005116940.046
tube morphogenesisGO:00352393490.045
regulation of autophagyGO:001050630.045
cell matrix adhesionGO:000716040.045
regulation of cellular amine metabolic processGO:003323800.044
positive regulation of cellular catabolic processGO:003133130.043
cell morphogenesisGO:00009022890.042
cell substrate adhesionGO:003158940.042
regulation of purine nucleotide catabolic processGO:003312120.041
cellular response to molecule of bacterial originGO:007121930.041
somatic muscle developmentGO:000752540.041
single organism nuclear importGO:190259330.041
chordate embryonic developmentGO:00430092710.041
positive regulation of epithelial cell proliferationGO:005067910.039
sensory organ developmentGO:00074233930.038
response to monosaccharideGO:003428430.038
cell cycleGO:0007049930.038
maintenance of locationGO:005123540.037
cellular response to chemical stimulusGO:00708871570.037
multicellular organism growthGO:003526440.036
establishment of protein localization to organelleGO:007259440.036
regulation of establishment of protein localizationGO:007020140.036
somite developmentGO:0061053960.035
regulation of cytoplasmic transportGO:190364940.035
regulation of synaptic growth at neuromuscular junctionGO:000858210.035
nuclear importGO:005117030.035
stem cell divisionGO:001714510.034
cell morphogenesis involved in neuron differentiationGO:00486671630.034
protein targeting to nucleusGO:004474430.033
gastrulationGO:00073692080.033
macroautophagyGO:001623610.033
localization of cellGO:00516742440.033
regulation of nucleocytoplasmic transportGO:004682220.032
response to endogenous stimulusGO:0009719830.032
amine metabolic processGO:000930820.032
positive regulation of purine nucleotide catabolic processGO:003312310.032
carboxylic acid metabolic processGO:0019752220.032
central nervous system neuron axonogenesisGO:0021955180.031
central nervous system projection neuron axonogenesisGO:0021952150.031
zymogen activationGO:003163830.030
regulation of protein transportGO:005122330.030
dorsal ventral pattern formationGO:00099531250.030
morphogenesis of an epitheliumGO:00020093330.029
cellular response to external stimulusGO:007149620.029
cellular component morphogenesisGO:00329893360.029
chemotaxisGO:00069351040.029
cellular response to starvationGO:000926710.028
regulation of nucleotide catabolic processGO:003081120.028
cellular amine metabolic processGO:004410620.028
regulation of protein targetingGO:190353320.028
synaptic growth at neuromuscular junctionGO:005112420.028
chemosensory behaviorGO:000763510.028
positive regulation of map kinase activityGO:004340630.027
single organism metabolic processGO:00447102170.027
blood vessel developmentGO:00015682460.027
gtp metabolic processGO:004603940.027
guanosine containing compound metabolic processGO:190106840.027
neuron projection developmentGO:00311751800.027
locomotor rhythmGO:004547530.027
regulation of multicellular organism growthGO:004001440.027
response to glucoseGO:000974930.026
autophagyGO:000691440.026
neuroblast proliferationGO:000740520.026
cell migration involved in gastrulationGO:0042074790.026
lipid storageGO:001991510.026
b cell activationGO:004211320.026
stem cell proliferationGO:007208940.025
ras protein signal transductionGO:000726570.025
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.025
adult behaviorGO:003053420.025
segmentationGO:0035282970.025
negative regulation of small gtpase mediated signal transductionGO:005105810.024
cellular respirationGO:004533330.024
negative regulation of synapse assemblyGO:005196420.024
modification dependent protein catabolic processGO:001994130.024
positive regulation of striated muscle cell differentiationGO:005115510.024
neuron differentiationGO:00301823530.024
eye developmentGO:00016542770.024
gtp catabolic processGO:000618420.024
cellular response to extracellular stimulusGO:003166820.024
carbohydrate homeostasisGO:003350010.024
proteolysis involved in cellular protein catabolic processGO:005160330.024
regulation of cellular amino acid metabolic processGO:000652100.024
phagocytosisGO:000690930.023
regulation of dendrite developmentGO:005077330.023
regulation of protein localization to nucleusGO:190018020.023
multi organism processGO:00517041340.023
positive regulation of cell cycleGO:004578730.023
growthGO:00400071740.023
positive regulation of transportGO:005105020.023
regulation of cell matrix adhesionGO:000195210.023
protein dephosphorylationGO:000647030.023
organic acid metabolic processGO:0006082310.023
protein acylationGO:004354330.023
guanosine containing compound catabolic processGO:190106920.023
single organism organelle organizationGO:19025891990.022
response to nutrientGO:000758430.022
lamellipodium organizationGO:009758110.022
positive regulation of nucleoside metabolic processGO:004597910.022
purine ribonucleoside monophosphate catabolic processGO:000916940.022
lipid homeostasisGO:005508830.022
secondary metabolic processGO:001974830.022
gene expressionGO:00104672520.022
regulation of cell projection assemblyGO:006049140.022
regulation of dendrite morphogenesisGO:004881430.021
positive regulation of neuron deathGO:190121610.021
heart developmentGO:00075073130.021
organonitrogen compound metabolic processGO:1901564740.021
ameboidal type cell migrationGO:00016671430.021
neuron projection morphogenesisGO:00488121610.021
cell fate specificationGO:0001708680.021
regulation of photoreceptor cell differentiationGO:004653220.021
small molecule metabolic processGO:0044281770.021
protein acetylationGO:000647320.021
regulation of cellular ketone metabolic processGO:001056570.021
cellular response to biotic stimulusGO:007121630.021
regulation of cardiac muscle tissue developmentGO:005502410.021
negative regulation of kinase activityGO:003367340.021
cell substrate junction assemblyGO:000704420.021
rna localizationGO:000640340.020
modification dependent macromolecule catabolic processGO:004363230.020
negative regulation of protein phosphorylationGO:000193340.020
positive regulation of nucleotide catabolic processGO:003081310.020
cell cycle g1 s phase transitionGO:004484310.020
angiogenesisGO:00015251580.020
proteasomal protein catabolic processGO:001049820.020
signal transductionGO:00071654550.020
peptidyl lysine acetylationGO:001839420.020
positive regulation of muscle cell differentiationGO:005114910.020
negative regulation of protein serine threonine kinase activityGO:007190120.020
locomotionGO:00400113130.020
negative regulation of protein kinase activityGO:000646940.019
regulation of response to nutrient levelsGO:003210710.019
mitochondrion organizationGO:000700540.019
central nervous system neuron developmentGO:0021954290.019
regulation of cell activationGO:005086510.019
positive regulation of protein complex assemblyGO:003133420.019
regulation of protein complex assemblyGO:004325430.019
muscle tissue developmentGO:00605371100.019
cell surface receptor signaling pathwayGO:00071663250.019
regulation of developmental processGO:00507932470.019
regulation of intracellular protein transportGO:003315730.019
glucose homeostasisGO:004259310.019
response to stressGO:00069502630.019
oocyte maturationGO:000155640.018
regulation of protein catabolic processGO:004217610.018
deathGO:00162651210.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.018
positive regulation of biological processGO:00485182530.018
positive regulation of small gtpase mediated signal transductionGO:005105710.018
regulation of bindingGO:005109830.018
p38mapk cascadeGO:003806610.018
cellular component disassemblyGO:002241110.018
positive regulation of neuron apoptotic processGO:004352510.018
cellular nitrogen compound metabolic processGO:00346412900.018
cellular aromatic compound metabolic processGO:00067252950.018
cellular ketone metabolic processGO:0042180110.018
regulation of cell substrate adhesionGO:001081010.018
centrosome organizationGO:005129710.017
lamellipodium assemblyGO:003003210.017
regulation of nucleoside metabolic processGO:000911820.017
negative regulation of cell differentiationGO:0045596460.017
phosphate containing compound metabolic processGO:00067961080.017
regulation of reactive oxygen species metabolic processGO:200037720.017
cellular macromolecule metabolic processGO:00442603910.017
axon developmentGO:00615641660.017
neuron neuron synaptic transmissionGO:000727010.017
positive regulation of wound healingGO:009030310.017
cellular response to growth factor stimulusGO:0071363390.017
regulation of gtp catabolic processGO:003312420.017
cellular response to endogenous stimulusGO:0071495680.017
nucleic acid templated transcriptionGO:00976591810.016
neuron developmentGO:00486662620.016
response to external biotic stimulusGO:0043207970.016
embryonic organ developmentGO:00485683810.016
regulation of epithelial cell proliferationGO:005067830.016
axon guidanceGO:0007411860.016
negative regulation of nucleocytoplasmic transportGO:004682320.016
b cell differentiationGO:003018310.016
purine nucleoside monophosphate catabolic processGO:000912840.016
response to hexoseGO:000974630.016
nitrogen compound metabolic processGO:00068073190.016
negative chemotaxisGO:005091910.016
axon extensionGO:0048675450.016
cellular amino acid metabolic processGO:000652070.016
protein secretionGO:000930610.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016
cellular response to nutrient levelsGO:003166920.016
tissue remodelingGO:004877140.016
regulation of gtpase activityGO:004308720.016
cell projection morphogenesisGO:00488582440.016
response to abiotic stimulusGO:00096281220.016
protein polymerizationGO:005125840.016
regulation of protein import into nucleusGO:004230620.016
glial cell migrationGO:000834730.015
regulation of synaptic plasticityGO:004816710.015
response to other organismGO:0051707970.015
negative regulation of cytoplasmic transportGO:190365020.015
endothelial cell fate commitmentGO:006083930.015
intracellular mrna localizationGO:000829810.015
regulation of cell differentiationGO:00455951420.015
cellular protein catabolic processGO:004425740.015
cell migrationGO:00164772370.015
oxoacid metabolic processGO:0043436310.015
lateral inhibitionGO:004633110.015
negative regulation of epithelial cell proliferationGO:005068010.015
actin polymerization or depolymerizationGO:000815420.015
protein phosphorylationGO:0006468470.015
developmental growthGO:00485891660.015
small gtpase mediated signal transductionGO:000726480.015
cilium morphogenesisGO:0060271850.015
vasculature developmentGO:00019442780.015
regulation of cellular protein catabolic processGO:190336210.015
positive regulation of cell adhesionGO:004578510.015
signal transduction in absence of ligandGO:003803410.015
cellular carbohydrate metabolic processGO:004426240.015
antimicrobial humoral responseGO:001973020.015
adherens junction organizationGO:003433240.015
nuclear exportGO:005116810.015
embryonic organ morphogenesisGO:00485622740.015
regulation of inflammatory responseGO:005072720.014
negative regulation of response to stimulusGO:00485851040.014
protein homooligomerizationGO:005126030.014
cell agingGO:000756920.014
urogenital system developmentGO:0001655970.014
negative regulation of biological processGO:00485193040.014
negative regulation of intracellular transportGO:003238730.014
cilium assemblyGO:0042384580.014
neuronal action potentialGO:0019228180.014
system processGO:00030081850.014
internal peptidyl lysine acetylationGO:001839320.014
actin filament polymerizationGO:003004120.014
internal protein amino acid acetylationGO:000647520.014
ubiquitin dependent protein catabolic processGO:000651130.014
determination of bilateral symmetryGO:00098552040.014
programmed cell deathGO:00125011190.014
multicellular organismal signalingGO:0035637220.014
multi organism cellular processGO:004476420.014
neurotransmitter transportGO:000683620.014
regulation of organelle assemblyGO:190211540.014
protein metabolic processGO:00195381830.014
phosphorus metabolic processGO:00067931090.014
regulation of filopodium assemblyGO:005148920.014
chromosome organization involved in meiosisGO:007019210.014
hair cell differentiationGO:0035315320.014
neuron projection guidanceGO:0097485860.014
g1 s transition of mitotic cell cycleGO:000008210.013
phototransductionGO:000760220.013
meiotic cell cycle processGO:190304630.013
neural crest cell migrationGO:0001755420.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
neurotransmitter secretionGO:000726920.013
nucleoside monophosphate catabolic processGO:000912540.013
cell deathGO:00082191210.013
positive regulation of translationGO:004572710.013
regulation of erk1 and erk2 cascadeGO:007037240.013
regulation of rho protein signal transductionGO:003502320.013
cellular response to organic substanceGO:00713101050.013
photoreceptor cell differentiationGO:0046530550.013
axon ensheathment in central nervous systemGO:003229120.013
regulation of transcription dna templatedGO:00063552130.013
meiotic nuclear divisionGO:000712640.013
atp catabolic processGO:000620040.013
pronephros developmentGO:0048793690.013
regulation of metabolic processGO:00192223590.013
cellular protein metabolic processGO:00442671290.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
cellular response to hypoxiaGO:007145610.013
biosynthetic processGO:00090582940.013
protein complex localizationGO:003150310.013
defense response to bacteriumGO:0042742220.013
organelle organizationGO:00069962270.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
meiotic chromosome segregationGO:004513230.012
muscle cell differentiationGO:00426921390.012
regulation of primary metabolic processGO:00800903110.012
actin cytoskeleton organizationGO:0030036630.012
negative regulation of defense responseGO:003134820.012
bmp signaling pathwayGO:0030509520.012
regulation of production of molecular mediator of immune responseGO:000270010.012
regulation of molecular functionGO:0065009700.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
ribonucleoside monophosphate catabolic processGO:000915840.012
convergent extensionGO:00600261180.012
response to biotic stimulusGO:0009607970.012
regulation of cellular metabolic processGO:00313233200.012
regulation of response to biotic stimulusGO:000283120.012
nucleic acid metabolic processGO:00903042440.012
regulation of anatomical structure morphogenesisGO:00226031300.012
positive regulation of muscle tissue developmentGO:190186310.012
immune system developmentGO:00025201910.012
synaptic vesicle localizationGO:009747910.012
response to transition metal nanoparticleGO:1990267280.012
positive regulation of i kappab kinase nf kappab signalingGO:004312330.012
ear developmentGO:00435831270.012
positive regulation of camp metabolic processGO:003081620.012
extrinsic apoptotic signaling pathwayGO:009719130.012
actin mediated cell contractionGO:007025210.012
negative regulation of map kinase activityGO:004340720.012
positive regulation of canonical wnt signaling pathwayGO:009026340.012
regulation of neural precursor cell proliferationGO:200017730.012
taxisGO:00423301090.012
positive regulation of gtp catabolic processGO:003312610.012
epidermal cell fate specificationGO:000995740.012
peptidyl serine phosphorylationGO:001810510.012
gastrulation with mouth forming secondGO:0001702440.012
germ line stem cell divisionGO:004207810.012
negative regulation of intracellular protein transportGO:009031730.012
retina development in camera type eyeGO:00600411460.012
positive regulation of cellular amino acid metabolic processGO:004576400.011
osteoclast differentiationGO:003031610.011
central nervous system neuron differentiationGO:0021953740.011
i kappab kinase nf kappab signalingGO:000724940.011
regulation of signalingGO:00230512350.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.011
regulation of signal transductionGO:00099662250.011
protein localization to plasma membraneGO:007265910.011
viral processGO:001603210.011
cell motilityGO:00488702440.011
cortical cytoskeleton organizationGO:003086510.011
regulation of multicellular organismal processGO:00512392770.011
regulation of response to extracellular stimulusGO:003210410.011
cell projection assemblyGO:0030031640.011
negative regulation of ras protein signal transductionGO:004658010.011
production of molecular mediator of immune responseGO:000244020.011
camera type eye developmentGO:00430102220.011
negative regulation of mapk cascadeGO:004340940.011
somitogenesisGO:0001756870.011
negative regulation of protein import into nucleusGO:004230820.011
regulation of nervous system developmentGO:0051960900.011
cellular response to fibroblast growth factor stimulusGO:0044344220.011
regulation of neurotransmitter secretionGO:004692810.011
peptide transportGO:001583310.011
negative regulation of secretion by cellGO:190353120.011
positive regulation of protein polymerizationGO:003227320.011
inositol lipid mediated signalingGO:004801720.011
specification of symmetryGO:00097992040.011
heterocycle metabolic processGO:00464832900.011
cytoplasm organizationGO:000702840.011
cellular protein modification processGO:00064641000.011
transmembrane transportGO:00550851200.011
sensory perception of chemical stimulusGO:000760630.011
regulation of biosynthetic processGO:00098892500.011
regulation of cell motilityGO:2000145460.011
startle responseGO:000196440.011
erk1 and erk2 cascadeGO:007037140.011
positive regulation of myeloid cell differentiationGO:004563920.011
regulation of multicellular organismal developmentGO:20000262230.011
positive regulation of cytoskeleton organizationGO:005149530.011
regulation of endothelial cell proliferationGO:000193610.011
positive regulation of nucleobase containing compound metabolic processGO:0045935690.011
regulation of fibroblast growth factor receptor signaling pathwayGO:0040036200.011
regulation of transmembrane transporter activityGO:002289820.011
protein modification processGO:00362111000.011
endosomal transportGO:001619720.011
regulation of cell morphogenesisGO:0022604420.011
regulation of cellular component organizationGO:0051128860.011
protein modification by small protein removalGO:007064610.011
positive regulation of multi organism processGO:004390230.011
blood vessel endothelial cell differentiationGO:006083720.011
interspecies interaction between organismsGO:004441940.011
microtubule based processGO:0007017600.011
wound healingGO:0042060900.011
response to bacteriumGO:0009617580.011
nephric duct developmentGO:0072176130.011
negative regulation of autophagyGO:001050710.011
hepaticobiliary system developmentGO:0061008980.011
nucleoside phosphate metabolic processGO:0006753280.010
negative regulation of multi organism processGO:004390130.010
response to woundingGO:00096111160.010
regulation of stem cell differentiationGO:200073640.010
rho protein signal transductionGO:000726650.010
camera type eye morphogenesisGO:00485931080.010
sensory perception of smellGO:000760820.010
ventricular cardiac muscle tissue developmentGO:000322930.010
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.010
positive regulation of erk1 and erk2 cascadeGO:007037420.010
macromolecule modificationGO:00434121110.010
b cell mediated immunityGO:001972430.010
aromatic compound biosynthetic processGO:00194382170.010
regulation of cellular macromolecule biosynthetic processGO:20001122220.010
regulation of glial cell differentiationGO:004568540.010
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.010
cellular response to decreased oxygen levelsGO:003629410.010
transcription dna templatedGO:00063511810.010
regulation of transporter activityGO:003240920.010
establishment of protein localization to plasma membraneGO:009000210.010
aorta morphogenesisGO:003590930.010
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.010
skeletal system developmentGO:00015011810.010
pericardium developmentGO:006003910.010
liver developmentGO:0001889960.010

capn2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
bone marrow diseaseDOID:496100.031
anemiaDOID:235500.031
immune system diseaseDOID:291400.031
aplastic anemiaDOID:1244900.031
hematopoietic system diseaseDOID:7400.031
disease of anatomical entityDOID:700.031
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
nervous system diseaseDOID:86300.016
organ system cancerDOID:005068600.012